keyword
MENU ▼
Read by QxMD icon Read
search

safire

keyword
https://www.readbyqxmd.com/read/29135034/implementation-and-performance-of-the-artificial-force-induced-reaction-method-in-the-grrm17-program
#1
Satoshi Maeda, Yu Harabuchi, Makito Takagi, Kenichiro Saita, Kimichi Suzuki, Tomoya Ichino, Yosuke Sumiya, Kanami Sugiyama, Yuriko Ono
This article reports implementation and performance of the artificial force induced reaction (AFIR) method in the upcoming 2017 version of GRRM program (GRRM17). The AFIR method, which is one of automated reaction path search methods, induces geometrical deformations in a system by pushing or pulling fragments defined in the system by an artificial force. In GRRM17, three different algorithms, that is, multicomponent algorithm (MC-AFIR), single-component algorithm (SC-AFIR), and double-sphere algorithm (DS-AFIR), are available, where the MC-AFIR was the only algorithm which has been available in the previous 2014 version...
November 14, 2017: Journal of Computational Chemistry
https://www.readbyqxmd.com/read/29114620/reducing-radiation-dose-and-enhancing-imaging-quality-of-4dct-for-radiation-therapy-using-iterative-reconstruction-algorithms
#2
George Noid, An Tai, Guang-Pei Chen, Jared Robbins, X Allen Li
Purpose: Four-dimensional computed tomography (CT) images are typically used to quantify the necessary internal target volumes for thoracic and abdominal tumors. However, 4-dimensional CT is typically associated with excessive imaging dose to patients and the situation is exacerbated when using repeat 4-dimensional CT imaging on a weekly or daily basis throughout fractionated therapy. The aim of this work is to evaluate an iterative reconstruction (IR) algorithm that helps reduce the imaging dose to the patient while maintaining imaging quality as quantified by point spread function and contrast-to-noise ratios (CNRs)...
July 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/29066126/diagnostic-performance-of-a-low-dose-triple-rule-out-ct-angiography-using-safire-in-emergency-department
#3
S Si-Mohamed, J Greffier, X Bobbia, A Larbi, J Delicque, E Khasanova, J-P Beregi, F Macri
OBJECTIVES: To compare the diagnostic performance of "triple rule out" CT angiography (TRO-CTA) at 100kVp using sinogram affirmed iterative reconstruction (SAFIRE) with TRO-CTA at 120kVp using filtered back projection (FBP) in patients with acute chest pain. METHODS: Consecutive non-prepared patients from a single radiological emergency department, referred for acute chest pain evaluation with TRO-CTA, were randomly assigned to two different TRO-CTA protocols. Fifty patients (66% men; mean age, 66...
October 20, 2017: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/29042698/evaluating-low-kv-dual-source-ct-angiography-by-high-pitch-spiral-acquisition-and-iterative-reconstruction-in-pediatric-congenital-heart-disease-patients
#4
Yohei Marukawa, Shuhei Sato, Takashi Tanaka, Akihiro Tada, Yuichiro Kanie, Susumu Kanazawa
We retrospectively evaluated the qualities of pediatric cardiovascular dual-source computed tomography (DSCT) images reconstructed by sinogram-affirmed iterative reconstruction (SAFIRE) and filtered back projection (FBP). We analyzed the cases of 287 congenital heart disease (CHD) patients < 5 years old, referred to our department in August 2013-March 2015. We divided them into two groups according to tube voltage (70 kVp, n=147; 80 kVp, n=140). All images were acquired by a CARE kV system and reconstructed by FBP and SAFIRE...
October 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/29029768/value-of-100-kvp-scan-with-sinogram-affirmed-iterative-reconstruction-algorithm-on-a-single-source-ct-system-during-whole-body-ct-for-radiation-and-contrast-medium-dose-reduction-an-intra-individual-feasibility-study
#5
Y Nagayama, T Nakaura, S Oda, A Tsuji, J Urata, M Furusawa, S Tanoue, D Utsunomiya, Y Yamashita
AIM: To perform an intra-individual investigation of the usefulness of a contrast medium (CM) and radiation dose-reduction protocol using single-source computed tomography (CT) combined with 100 kVp and sinogram-affirmed iterative reconstruction (SAFIRE) for whole-body CT (WBCT; chest-abdomen-pelvis CT) in oncology patients. MATERIALS AND METHODS: Forty-three oncology patients who had undergone WBCT under both 120 and 100 kVp protocols at different time points (mean interscan intervals: 98 days) were included retrospectively...
October 10, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28842662/low-tube-voltage-liver-mdct-with-sinogram-affirmed-iterative-reconstructions-for-the-detection-of-hepatocellular-carcinoma
#6
B Pregler, L P Beyer, A Teufel, C Niessen, C Stroszczynski, H Brodoefel, P Wiggermann
Aim of this study was to compare low tube voltage computed tomography (80 kV) of the liver using iterative image reconstruction (SAFIRE) with standard computed tomography (120 kV) using filtered back-projection (FBP) for the detection of hepatocellular carcinoma (HCC). 46 patients (43 men) with 93 HCC confirmed by 3 T MRI with Gd-EOB-DPTA, in inconclusive cases combined with contrast-enhanced ultrasound, underwent dual-energy CT. The raw data of the 80 kV tube was reconstructed using the iterative reconstruction algorithm SAFIRE with two strengths (I3 and I5)...
August 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28807365/-the-breakthrough-of-personalized-medicine-new-hopes-and-new-challenges
#7
REVIEW
Ronan Flippot, Christophe Massard, Edouard Auclin, David Azria, Héloïse Bourien, Philippe Rochigneux, Antoine Schernberg, Loïc Verlingue, Lara Zafrani, Stéphane Vignot
The development of personalized medicine in oncology is based on biomarkers that help select populations for more efficient and less toxic therapies. The onset of molecular biology led to new paradigms in drug development, with efficacy data reported in early clinical trials and accelerated approvals. Multiple clinical trials, including SHIVA, SAFIR-01 and MOSCATO-01, have been developed to evaluate the interest of treatment decision-making based on tumor molecular profiling, with the ambition to replace historical clinical and pathological classifications...
September 2017: Bulletin du Cancer
https://www.readbyqxmd.com/read/28780298/comparative-cost-analysis-teleurology-versus-conventional-face-to-face-clinics
#8
Vitaly Zholudev, Ilan J Safir, Isabella M Issa, Mark N Painter, John A Petros, Christopher P Filson, Muta M Issa
OBJECTIVES: To compare costs associated with teleurology versus face-to-face clinic visits for initial outpatient hematuria evaluation. METHODS: The analysis included three cost domains: transportation, clinic operations, and patient time. Transportation cost was based on standard government travel reimbursement. Clinic staff cost was based on hourly salary plus fringe benefits. For a face-to face clinic encounter, patient time included time spent for travel, parking, walking to and from clinic, check-in and check-out times, nursing evaluation, urological evaluation, laboratory time, and waiting time...
August 2, 2017: Urology
https://www.readbyqxmd.com/read/28764856/image-quality-of-ct-angiography-in-young-children-with-congenital-heart-disease-a%C3%A2-comparison-between-the-sinogram-affirmed-iterative-reconstruction-safire-and-advanced-modelled-iterative-reconstruction-admire-algorithms
#9
S B Nam, D W Jeong, K S Choo, K J Nam, J-Y Hwang, J W Lee, J Y Kim, S J Lim
AIM: To compare the image quality of computed tomography angiography (CTA) reconstructed by sinogram-affirmed iterative reconstruction (SAFIRE) with that of advanced modelled iterative reconstruction (ADMIRE) in children with congenital heart disease (CHD). MATERIAL AND METHODS: Thirty-one children (8.23±13.92 months) with CHD who underwent CTA were enrolled. Images were reconstructed using SAFIRE (strength 5) and ADMIRE (strength 5). Objective image qualities (attenuation, noise) were measured in the great vessels and heart chambers...
July 29, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28761180/iterative-reconstruction-improves-detection-of-in-stent-restenosis-by-high-pitch-dual-source-coronary-ct-angiography
#10
Junjie Yang, Xiaobo Yang, Carlo N De Cecco, Taylor M Duguay, Zhiye Chen, Christian Tesche, U Joseph Schoepf, Yundai Chen
Recent studies demonstrated that sinogram affirmed iterative reconstructions (SAFIRE) can produce higher-resolution images with greater robustness for the reduction of various imaging artefacts. Eighty-five patients were prospectively evaluated and underwent a high-pitch spiral acquisition CT scan. In-stent noise, signal-to-noise ratio(SNR), stent-lumen attenuation increase ratio (SAIR), and subjective image quality score were measured and compared between the SAFIRE and Filter back projection (FBP) reconstructions...
July 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28713667/absent-congenital-cervical-pedicle-nearly-misdiagnosed-as-a-facet-dislocation-a-case-report
#11
Scott Safir, Jonathan Rasouli, Jeremy Steinberger, Branko Skovrlj, Amish Doshi, Konstantinos Margetis, Saadi Ghatan
BACKGROUND: Cervical spinal injury encompasses up to 1.5% of all pediatric injuries. Children, and more specifically infants, are a difficult subset of patients to obtain neurological exam in the setting of trauma, thus necessitating the use of cervical X-rays, CT scans, and MRI imaging. CASE DESCRIPTION: A healthy, 15-month-old boy had an unwitnessed fall down a flight of stairs and received a CT scan of the head and cervical spine in the emergency department due to cephalohematoma and mechanism of injury...
September 2017: Interdisciplinary Neurosurgery: Advanced Techniques and Case Management
https://www.readbyqxmd.com/read/28693049/hybrid-repair-techniques-for-complex-aneurysms-and-dissections-involving-the-aortic-arch-and-thoracic-aorta
#12
Rami Tadros, Scott R Safir, Peter L Faries, Daniel K Han, Sharif Ellozy, Rajiv K Chander, James F McKinsey, Michael L Marin, Allan S Stewart
Aortic aneurysms involving the ascending aorta, aortic arch, and descending thoracic aorta have been a challenging entity to surgically treat for over 60 years. Despite the mortality of the disease, early open surgical procedures also had significant morbidity and mortality. The inherent risk in treating multiple anatomic segments simultaneously led to the innovation of the staged elephant trunk (ET) approach by Borst in 1983. To avoid the thoracotomy and associated complications related to the second stage of the procedure, an endovascular completion paradigm was begun by Volodos in 1991...
July 25, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/28693048/the-use-of-branched-endografts-for-the-aortic-arch-in-the-endovascular-era
#13
Rami O Tadros, Scott R Safir, Peter L Faries, Daniel K Han, Rajiv K Chander, Cherrie Z Abraham, Michael L Marin, Allan S Stewart
The endovascular realm has steadily increased its footing in the treatment of the aorta and all of its territories since the foundational case in 1990 by Parodi. The aortic arch, however, continues to be one of the last bastions for treatment via open surgery, which remains the gold standard. Significant comorbidity and prior cardiac surgery prevent open surgery from being the only preferred option, allowing novel endovascular procedures to be considered. Since 1999, more advanced endovascular systems have been created by companies such as Cook Medical, Bolton Medical, Medtronic, Endospan, Gore Medical, and, recently, Kawasumi...
July 25, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/28678818/image-quality-diagnostic-accuracy-and-potential-for-radiation-dose-reduction-in-thoracoabdominal-ct-using-sinogram-affirmed-iterative-reconstruction-safire-technique-in-a-longitudinal-study
#14
Michael Scharf, Stephanie Brendel, Katja Melzer, Christian Hentschke, Matthias May, Michael Uder, Michael M Lell
OBJECTIVE: To step-wise evaluate image quality of sinogram-affirmed iterative reconstruction (SAFIRE) in reduced-dose (RD) thoracoabdominal computed tomography (CT) compared to full-dose (FD) and RD filtered back projection (FBP) in a longitudinal study. MATERIALS AND METHODS: 122 patients were included in this prospective study. 49 patients (14 men: mean age ± SD, 56±0.4 years; 35 women: 58±1.3 years) completed FD, RD1 (80%-dose) and RD2 (60%-dose) thoracoabdominal CT...
2017: PloS One
https://www.readbyqxmd.com/read/28608697/perspectives-of-cannabinoid-type-2-receptor-cb2r-ligands-in-neurodegenerative-disorders-structure-affinity-relationship-safir-and-structure-activity-relationship-sar-studies
#15
Francesco Spinelli, Elena Capparelli, Carmen Abate, Nicola A Colabufo, Marialessandra Contino
Up-regulation of CB2R on activated microglial cells, the first step in neurodegeneration, has been widely demonstrated, and this finding makes the receptor a promising target in the early diagnosis and treatment of several neurodegenerative disorders such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and multiple sclerosis (MS). The development of CB2R PET ligands could help demonstrate the neurodegenerative pathogenesis, thus providing useful tools for characterizing the role of neuroinflammation in the progression of these disorders...
June 30, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28455469/management-of-massive-acetabular-bone-defects-in-revision-arthroplasty-of-the-hip-using-a-reconstruction-cage-and-porous-metal-augment
#16
T J Mäkinen, M Abolghasemian, E Watts, S G Fichman, P Kuzyk, O A Safir, A E Gross
AIMS: It may not be possible to undertake revision total hip arthroplasty (THA) in the presence of massive loss of acetabular bone stock using standard cementless hemispherical acetabular components and metal augments, as satisfactory stability cannot always be achieved. We aimed to study the outcome using a reconstruction cage and a porous metal augment in these patients. PATIENTS AND METHODS: A total of 22 acetabular revisions in 19 patients were performed using a combination of a reconstruction cage and porous metal augments...
May 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28296730/image-quality-evaluation-for-care-kv-technique-combined-with-iterative-reconstruction-for-chest-computed-tomography-scanning
#17
RANDOMIZED CONTROLLED TRIAL
Bin Yang, Zheng-Liang Li, Yi Gao, Ya-Ying Yang, Wei Zhao
BACKGROUND: To investigate the radiation dose and image quality for iterative reconstruction combined with the CARE kV technique in chest computed tomography (CT) scanning for physical examination. METHODS: A total of 130 patients who underwent chest CT scanning were randomly chosen and the quality reference value was set as 80 mAs. The scanning scheme was set and the patients were randomly divided into groups according to the scanning scheme. Sixty patients underwent a chest scan with 100 kV using the CARE kV technique and SAFIRE reconstruction (value=3) (experimental group) and the other 70 patients underwent chest scanning with 120 kV (control group)...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28274634/assessment-of-new-triplet-forming-artificial-nucleobases-as-rna-ligands-directed-towards-hcv-ires-iiid-loop
#18
Mauro Safir Filho, Anthony R Martin, Rachid Benhida
We report the synthesis of two new artificial nucleobase scaffolds, 1 and 2, featuring adequate hydrogen bonding donors and acceptors for the molecular recognition of U:A and C:G base pairs, respectively. The tethering of these structures to various amino acids and the assessment of these artificial nucleobase-amino acid conjugates as RNA ligands against a model of HCV IRES IIId domain are also reported. Compound 1e displayed the highest affinity (Kd twice lower than neomycin - control). Moreover, it appears that this interaction is enthalpically and entropically favored...
April 15, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28170300/effect-of-radiation-dose-reduction-and-reconstruction-algorithm-on-image-noise-contrast-resolution-and-detectability-of-subtle-hypoattenuating-liver-lesions-at-multidetector-ct-filtered-back-projection-versus-a-commercial-model-based-iterative-reconstruction
#19
Justin Solomon, Daniele Marin, Kingshuk Roy Choudhury, Bhavik Patel, Ehsan Samei
Purpose To determine the effect of radiation dose and iterative reconstruction (IR) on noise, contrast, resolution, and observer-based detectability of subtle hypoattenuating liver lesions and to estimate the dose reduction potential of the IR algorithm in question. Materials and Methods This prospective, single-center, HIPAA-compliant study was approved by the institutional review board. A dual-source computed tomography (CT) system was used to reconstruct CT projection data from 21 patients into six radiation dose levels (12...
September 2017: Radiology
https://www.readbyqxmd.com/read/28125231/improved-fluorescent-protein-contrast-and-discrimination-by-optically-controlling-dark-state-lifetimes
#20
Yen-Cheng Chen, Robert M Dickson
Modulation and optical control of photoswitchable fluorescent protein (PS-FP) dark state lifetimes drastically improves sensitivity and selectivity in fluorescence imaging. The dark state population of PS-FPs generates an out-of-phase fluorescence component relative to the sinusoidally modulated 488 nm laser excitation. Because this apparent phase advanced emission results from slow recovery to the fluorescent manifold, we hasten recovery and, therefore, modulation frequency by varying coillumination intensity at 405 nm...
February 16, 2017: Journal of Physical Chemistry Letters
keyword
keyword
63757
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"