keyword
https://read.qxmd.com/read/38510669/fibrosis-signature-of-anastomotic-margins-for-predicting-anastomotic-stenosis-in-rectal-cancer-with-neoadjuvant-chemoradiotherapy-and-sphincter-preserving-surgery
#1
JOURNAL ARTICLE
Zhun Liu, Meifang Xu, Qian Yu, Jianyuan Song, Qili Lin, Shenghui Huang, Zhifen Chen, Ying Huang, Pan Chi
BACKGROUND: Radiation-induced colorectal fibrosis (RICF) is a common pathological alteration among patients with rectal cancer undergoing neoadjuvant chemoradiotherapy (nCRT). Anastomotic stenosis (AS) causes symptoms and negatively impacts patients' quality of life and long-term survival. In this study, we aimed to evaluate the fibrosis signature of RICF and develop a nomogram to predict the risk of AS in patients with rectal cancer undergoing nCRT. METHODS: Overall, 335 pairs of proximal and distal margins were collected and randomly assigned at a 7:3 ratio to the training and testing cohorts...
2024: Gastroenterology Report
https://read.qxmd.com/read/38476306/endoscopic-submucosal-dissection-for-resections-larger-than-10-cm-outcomes-from-a-portuguese-center
#2
JOURNAL ARTICLE
Raquel R Mendes, Pedro Barreiro, André Mascarenhas, Ana Rita Franco, Liliana Carvalho, Cristina Chagas
BACKGROUND: Endoscopic submucosal dissection (ESD) is a minimally invasive technique for en bloc resection of superficial neoplastic lesions, independent of their size. However, for giant gastrointestinal superficial neoplasia, the risk of invasive cancer is higher, and ESD is typically challenging. Despite the increasing literature on giant resections, data on their efficacy and safety are still lacking. OBJECTIVE: The aim of this study was to describe ESD outcomes from a Portuguese center, compare them with other international studies, and analyze the possible risk factors influencing outcomes...
February 2024: GE Portuguese Journal of Gastroenterology
https://read.qxmd.com/read/38476304/endoscopic-submucosal-dissection-is-safe-and-effective-for-lesions-located-at-the-anorectal-junction-analysis-from-two-referral-european-centers
#3
JOURNAL ARTICLE
Mariana Figueiredo Ferreira, Margarida Marques, Rui Morais, Arnaud Lemmers, Guilherme Macedo, João Santos-Antunes
INTRODUCTION: Endoscopic submucosal dissection (ESD) is a well-established resection technique for colorectal superficial tumors, but its role in the treatment of anorectal junction (ARJ) lesions still remains to be determined. With this study, we aimed to evaluate the feasibility, safety, and efficacy of ESD for the resection of ARJ lesions, in comparison to more proximal rectal lesions. METHODS: We performed a retrospective analysis of prospectively collected data concerning all consecutive rectal ESD procedures performed in two European centers, from 2015 to 2021...
February 2024: GE Portuguese Journal of Gastroenterology
https://read.qxmd.com/read/38464915/adult-sigmoid-intussusception-resembling-rectal-prolapse-a-case-report
#4
Tsung-Jung Tsai, Yu Shih Liu
BACKGROUND: Rectal prolapse arises from benign etiology. When symptoms of internal intussusception mirror those of rectal prolapse, a misdiagnosis is possible, especially under limited clinical presentation. It is crucial to recognize and differentiate rectal prolapse from internal intussusception because the two diagnoses have different prognoses. Here, we describe a case of adult sigmoid intussusception presenting as rectal prolapse. CASE SUMMARY: A 64-year-old woman with no known medical history visited a gastrointestinal outpatient department due to hard bloody stool defecation for 1 wk followed by constipation for 3 d...
February 26, 2024: World Journal of Clinical Cases
https://read.qxmd.com/read/38463020/y-z-deformable-magnetic-ring-for-the-treatment-of-rectal-stricture-a-case-report-and-review-of-literature
#5
Miao-Miao Zhang, Huan-Chen Sha, Yuan-Fa Qin, Yi Lyu, Xiao-Peng Yan
BACKGROUND: Treatment of postoperative anastomotic stenosis for colorectal cancer is often challenging, especially for patients who do not respond well to endoscopy. In cases where patients have undergone an enterostomy, the stenosis can be easily resolved through magnetic compression. However, common magnetic compression techniques cannot be performed on those without enterostomy. We designed a novel Y-Z deformable magnetic ring (Y-Z DMR) and successfully applied it to a patient with a stenosis rectal anastomosis and without enterostomy after rectal cancer surgery...
February 14, 2024: World Journal of Gastroenterology: WJG
https://read.qxmd.com/read/38402391/does-transanal-drainage-tubes-placement-have-an-impact-on-the-incidence-of-anastomotic-leakage-after-rectal-cancer-surgery-a-systematic-review-and-meta-analysis
#6
JOURNAL ARTICLE
Yating Liu, Xuhua Hu, Yu Huang, Xu Yin, Pengfei Zhang, Yaoguang Hao, Hongyan Li, Guiying Wang
BACKGROUND: Whether Transanal drainage tubes (TDTs) placement reduces the occurrence of anastomotic leakage (AL) after rectal cancer (RC) surgery remains controversial. Most existing meta-analyses rely on retrospective studies, while the prospective studies present an inadequate level of evidence. METHODS: A systematic review and meta-analysis of prospective studies on TDTs placement in RC patients after surgery was conducted. The main analysis index was the incidence of AL, Grade B AL, and Grade C AL, while secondary analysis index was the incidence of anastomotic bleeding, incision infection, and anastomotic stenosis...
February 24, 2024: BMC Cancer
https://read.qxmd.com/read/38369963/a-new-surgical-technique-robotic-intracorporeal-kono-s-anastomosis-in-crohn-s-a-safety-and-feasibility-case-series-on-short-term-outcomes
#7
JOURNAL ARTICLE
Bo P Smalbroek, Floris B Poelmann, Anke B Smits
AIM: The Kono-S anastomosis was introduced as a possible solution to the high surgical recurrence rates in Crohn's disease. However, this technique is known to be challenging, which is why it was originally performed in an extracorporeal setting. The aim of this case series was to assess safety, in terms of intra-/postoperative complications, and feasibility, in terms of successful performance of anastomosis, of a robot-assisted intracorporeal Kono-S anastomosis. METHOD: This is a prospective single-centre consecutive case series...
February 19, 2024: Colorectal Disease
https://read.qxmd.com/read/38350378/robotic-high-anterior-resection-for-rectal-cancer-with-hand-sewn-gambee-anastomosis-after-metal-stent-placement-in-a-colorectal-malignant-stricture-a-case-report
#8
Toshiyuki Suzuki, Akiyo Matsumoto, Takahiko Akao, Hiroshi Matsumoto
INTRODUCTION: Robot-assisted surgery is increasingly deployed in colorectal surgery, and decompression surgery using a stent is considered a standard treatment for malignant stenosis of the large intestine. Surgery after stent placement is also frequently performed. However, the anastomosis method remains controversial. PRESENTATION OF CASE: A 75-year-old woman visited our hospital's internal medicine department with chief complaints of bloody stool and constipation for the past year and colonoscopy was scheduled...
February 10, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38345513/lymphogranuloma-venereum-an-unusual-cause-of-rectal-stenosis
#9
JOURNAL ARTICLE
Alejandro Hueso Mor, Ana Soto Sánchez, María de Armas-Conde, Ricardo Hernández-Alonso, Eduardo Pérez Sánchez, Moisés Hernández Barroso, Julio César Jordán-Balanzá
Lymphogranuloma Venereum (LGV) is a notifiable disease linked to high-risk sexual practices such as cruising, chemsex, or orgies. The anorectal manifestation is associated with receptive anal sex and presents with characteristic symptoms such as proctitis, tenesmus, suppuration, and in advanced cases, anorectal fistulas or stenosis. The case of a 57-year-old man engaging in high-risk sexual practices is presented, showing symptoms such as discharge, fistulizations, rectal stenosis, and a weight loss of 15 kg...
February 12, 2024: Revista Española de Enfermedades Digestivas
https://read.qxmd.com/read/38303194/-a-case-of-rectal-cancer-that-could-be-safely-resected-by-laparoscopic-surgery-after-capecitabine-plus-l-ohp-plus-cetuximab-as-pre-operative-chemotherapy
#10
JOURNAL ARTICLE
Yoshiyuki Fukuda, Izuru Otsubo, Hayato Miyazaki, Takuya Kikuchi, Shunsuke Kusano, Noritoshi Mizuta, Hiroshi Ashitani, Kozo Tsunemi, Akihiro Toyokawa
A 56-year-old woman. She was underwent a lower gastrointestinal endoscopy for bloody stool, and type 2 advanced rectal cancer was found. In CT scan, although distant metastasis is not found, the tumor has been expanded to the dorsal side. So, infiltration into the sacrum was suspected. For the risk of bleeding and residual tumor in circumferential resection surface, it was decided to perform pre-operative adjuvant chemotherapy. Because RAS gene has no mutation, the regimen chose CAPOX plus cetuximab. Although skin damage and cytopenia were observed, there was no appearance of adverse events that were intolerant, and 4 courses were performed...
December 2023: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://read.qxmd.com/read/38296841/the-use-of-core-descriptors-from-the-enigma-code-study-in-recent-literature-a-systematic-review
#11
REVIEW
Saher-Zahra Khan, Andrea Arline, Kate M Williams, Matthew J Lee, Emily Steinhagen, Sharon L Stein
AIM: The heterogeneity in data quality presented in studies regarding Crohn's anal fistula (CAF) limit extrapolation into clinical practice. The ENiGMA collaborators established a core descriptor set to standardize reporting of CAF. The aim of this work was to quantify the use of these descriptors in recent literature. METHOD: We completed a systematic review of PubMed and the Cochrane Library, extracting publications from the past 10 years specific to the clinical interventions and outcomes of CAF, and reported in line with PRISMA guidance...
January 31, 2024: Colorectal Disease
https://read.qxmd.com/read/38277570/laparoscopic-total-mesorectal-excision-versus-transanal-total-mesorectal-excision-for-mid-and-low-rectal-cancer-a-systematic-review-and-meta-analysis
#12
JOURNAL ARTICLE
Zhang Yi Chi, Ou Gang, Feng Xiao Li, Lu Ya, Zhou Zhijun, Du Yong Gang, Ran Dan, Liu Xin, Liu Yang, Zhang Peng, Luo Yi, Lin Dong, Zhang De Chun
BACKGROUND: Laparoscopic total mesorectal excision (LaTME) and transanal total mesorectal excision (TaTME) are popular mid and low rectal cancer trends. However, there is currently no systematic comparison between LaTME and TaTME of mid and low rectal cancer. Therefore, we systematically study the perioperative and pathological outcomes of LaTME and TaTME in mid and low rectal cancer. METHODS: Articles included searching through the Embase, Cochrane Library, PubMed, Medline, and Web of science for articles on LaTME and TaTME...
January 26, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38253773/application-of-y-z-deformable-magnetic-ring-for-recanalization-of-transanal-single-access-rectal-stricture
#13
JOURNAL ARTICLE
Miaomiao Zhang, Yingying Zhuang, Jianqi Mao, Mingyan Gong, Yuhan Zhang, Aihua Shi, Yi Lyu, Xiaopeng Yan
Magnetic compression anastomosis has been reported to have remarkable clinical outcomes. Here, we tested the applicability of a Y-Z deformable magnetic ring (DMR) for non-surgical manipulation of rectal stenosis (RS) in a beagle dog model under a transanal single-access condition. RS was modeled in 8 beagle dogs using partial ligation with silk thread. Under X-ray guidance, the Y-Z DMR was positioned at the proximal and distal ends of the RS, and the magnetic ring was bent into an "O" shape, such that the two rings were magnetically attracted...
January 22, 2024: Scientific Reports
https://read.qxmd.com/read/38250676/neoadjuvant-s-1-and-oxaliplatin-plus-bevacizumab-therapy-for-high-risk-locally-advanced-rectal-cancer-a-prospective-multicenter-phase-ii-study
#14
JOURNAL ARTICLE
Takuya Miura, Hajime Morohashi, Yoshiyuki Sakamoto, Takuji Kagiya, Tatsuya Hasebe, Yoshihito Nakayama, Hiromasa Fujita, Kenichi Hakamada
AIM: We report the short/mid-term results of surgery for high-risk locally advanced rectal cancer (LARC) after neoadjuvant chemotherapy (NAC, four courses of S-1 + oxaliplatin+ bevacizumab) without radiotherapy with the primary aim of ypT0-2. METHODS: High-risk LARC was defined as cT4b, mesorectal fascia (MRF) ≤1 mm (MRF+), or lateral lymph node metastasis (cLLN+) on high-resolution MRI. The planned 32 cases from April 2018 to December 2021 were all included...
January 2024: Annals of Gastroenterological Surgery
https://read.qxmd.com/read/38245945/extrahepatic-bile-duct-metastasis-from-rectal-adenocarcinoma-case-report-and-literature-review
#15
Amine Majdoubi, Anass El Achchi, Mohamed El Hammouti, Tareq Bouhout, Badr Serji
INTRODUCTION AND IMPORTANCE: Extrahepatic metastasis is an exceptional site for rectal adenocarcinoma. Its clinical and radiological presentations are similar to those of cholangiocarcinoma, and its management requires collaboration between surgeons, endoscopists, and oncologists. CASE PRESENTATION: We present a unique case of a 58-year-old woman previously treated two and a half years ago for middle rectal adenocarcinoma with liver metastasis. In the immediate postoperative period, following restoring digestive continuity, she presented cholestatic jaundice from malignant obstruction of the extrahepatic bile duct...
January 20, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38206727/analysis-of-postoperative-complications-in-children-treated-for-moderate-to-severe-anal-atresia-with-laparoscopic-versus-open-surgery-a-retrospective-study
#16
JOURNAL ARTICLE
Ying-Song Liu, Hai-Wei Zhu, Yi Wang, Da Ma
This study aimed to compare and analyze the postoperative complications and anal function after 3-stage laparoscopic-assisted anorectoplasty (LAARP) and conventional posterior sagittal anorectoplasty (PSARP) in the treatment of moderate to severe anal atresia in children. A total of 27 children with moderate to severe anal atresia who underwent conventional PSARP at the Dongguan Children Hospital between 2007 and 2011 were included in the control group, and 34 children with moderate to severe anal atresia who underwent 3-stage LAARP between 2012 and 2016 were included in the observation group...
December 29, 2023: Medicine (Baltimore)
https://read.qxmd.com/read/38205462/efficacy-of-pelvic-floor-muscle-training-for-postoperative-patients-with-rectal-cancer-a-systematic-review-and-meta-analysis
#17
REVIEW
Yuki Nakashima, Kenichi Fudeyasu, Yuki Kataoka, Shunsuke Taito, Takashi Ariie, Yukio Mikami
This study aimed to assess the effectiveness of pelvic floor muscle training (PFMT) for fecal incontinence (FI) and health-related quality of life (HR-QOL) after colorectal cancer surgery. This systematic review (SR) and meta-analysis included randomized controlled trials (RCTs) that examined the effects of PFMT after colorectal cancer surgery, which were extracted from several databases in January 2023. The primary outcomes were FI (Wexner scores), HR-QOL, and adverse events. We used the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach to assess the certainty of evidence (CoE)...
December 2023: Curēus
https://read.qxmd.com/read/38189960/gastrointestinal-involvement-in-stec-associated-hemolytic-uremic-syndrome-10%C3%A2-years-in-a-pediatric-center
#18
JOURNAL ARTICLE
Mario Giordano, Onofrio Iacoviello, Luisa Santangelo, Marida Martino, Diletta Torres, Vincenza Carbone, Gaia Scavia, Daniela Loconsole, Maria Chironna, Fernanda Cristofori, Ruggiero Francavilla
BACKGROUND: The gastrointestinal (GI) tract represents one of the main targets of typical hemolytic uremic syndrome (HUS) in children. In this observational study, we tried to establish (1) the main features of GI complications during STEC-HUS and (2) the relationship between Escherichia coli serotypes and Shiga toxin (Stx) variants with hepatopancreatic involvement. METHODS: A total of 79 STEC-HUS patients were admitted to our pediatric nephrology department between January 2012 and June 2021...
January 8, 2024: Pediatric Nephrology
https://read.qxmd.com/read/38160763/health-related-quality-of-life-in-patients-with-urethral-stenosis-after-radiation-treatment-for-prostate-cancer
#19
JOURNAL ARTICLE
Kennedy Dirk, Keith Rourke
OBJECTIVE: To evaluate patient-reported quality of life (PRQoL) in patients presenting with membranous urethral stenosis after prostate radiotherapy. Urethral stenosis is an under-reported complication after prostate radiotherapy with a particular deficiency in PRQoL. METHODS: Patients presenting with urethral stenosis after radiotherapy were retrospectively reviewed from 2004-2022. PRQoL was assessed via patient survey using the Expanded Prostate Cancer Index Composite for Clinical Practice (EPIC-CP)...
December 29, 2023: Urology
https://read.qxmd.com/read/38130982/-modified-penile-inversion-vaginoplasty-first-case-series-of-a-turkish-single-center
#20
JOURNAL ARTICLE
Ersan Arda, Mehmet Gürkan Arıkan, Hüsamettin Top
PURPOSE: The aim of this study was to share our outcomes, including complications and their management, of a "modified" penile inversion vaginoplasty (PIV) technique applied to transgender individuals, which we presume to be the first reported case series of a single center from Turkey. METHODS: A cross-sectional study, including adult transgender cases who underwent male to female gender-affirming surgery in our institution, between January 2015 and December 2019, was planned...
December 2023: Transgender Health
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