keyword
https://read.qxmd.com/read/38461165/exploring-the-complexities-of-megacystis-microcolon-intestinal-hypoperistalsis-syndrome-insights-from-genetic-studies
#21
REVIEW
Prasad K V Devavarapu, Kalyan Ram Uppaluri, Vrushabh Anil Nikhade, Kalyani Palasamudram, Kavutharapu Sri Manjari
Megacystis microcolon intestinal hypoperistalsis syndrome (MMIHS) is an uncommon genetic disorder inherited in an autosomal recessive pattern that affects the muscles that line the bladder and intestines. The most common genes associated with MMIHS mutations are ACTG2, LMOD1, MYH11, MYL9, MYLK, and PDCL3. However, the complete genetic landscape of MMIHS still needs to be fully understood. The diagnosis of MMIHS can be challenging. However, advances in prenatal and diagnostic techniques, such as ultrasound and fetal urine analysis, have improved the ability to detect the syndrome early...
March 9, 2024: Clinical Journal of Gastroenterology
https://read.qxmd.com/read/38452000/influence-of-nutritional-supplements-on-antibody-levels-in-pregnant-women-vaccinated-with-inactivated-sars-cov-2-vaccines
#22
JOURNAL ARTICLE
Xi Zhang, Xue Han, Baolan Chen, Xi Fu, Yajie Gong, Wenhan Yang, Qingsong Chen
BACKGROUND: Because of the significantly higher demand for nutrients during pregnancy, pregnant women are more likely to have nutrient deficiencies, which may adversely affect maternal and fetal health. The influence of nutritional supplements on the immune effects of inactivated SARS-CoV-2 vaccines during pregnancy is not clear. METHODS: In a multicenter cross-sectional study, we enrolled 873 pregnant women aged 18-45 y in Guangdong, China. The general demographic characteristics of pregnant women and their use of nutritional supplements were investigated, and the serum antibody levels induced by inactivated SARS-CoV-2 vaccines were measured...
2024: PloS One
https://read.qxmd.com/read/38451577/is-postpartum-depression-related-to-total-weight-gain-during-pregnancy-and-maternal-anemia
#23
JOURNAL ARTICLE
Serap Topkara Sucu, Elif Karaman, Caner Kose, Sadun Sucu, Hüseyin Levent Keskin
OBJECTIVE: This study aimed to investigate the effects of weight gain and maternal anemia on postpartum depression. METHODS: This is a prospective, single-center, case-control study. We recorded the demographic characteristics, blood ferritin level, and weight gain during the pregnancy. This study was planned between April 2023 and June 2023 in the Obstetrics and Gynecology Clinic of Ankara Etlik City Hospital. A total of 109 patients were enrolled in the study...
2024: Revista da Associação Médica Brasileira
https://read.qxmd.com/read/38446774/impact-of-prenatal-maternal-dietary-exclusion-on-childhood-obesity-and-overweight-risk
#24
JOURNAL ARTICLE
Brenton Horne, Enamul Kabir, Khorshed Alam
BACKGROUND: Child birthweight is a measure of fetal nutrition that is primarily determined by prenatal maternal (PM) diet. Child birthweight and child obesity/overweight risk are well established to be linked. Nevertheless, no studies have investigated the impact of PM dietary exclusion on child obesity/overweight risk or body mass index z-score (BMIz). OBJECTIVES: The study aimed to determine whether PM dietary exclusion affected the child's BMIz, obesity/overweight risk, whether child birthweight serves as a mediator of this, and whether PM use of dietary supplements can protect against this...
2024: PloS One
https://read.qxmd.com/read/38442954/outcomes-following-the-adoption-of-standard-parenteral-nutrition-in-preterm-infants-a-whole-population-non-concurrent-control-study
#25
JOURNAL ARTICLE
Jessica Burgess-Shannon, Mohammad Chehrazi, Julia Lanoue, Neena Modi, Sabita N Uthaya
OBJECTIVE: To evaluate the impact of a quality improvement project of the adoption of standard parenteral nutrition (SPN) in preterm infants. DESIGN: Retrospective, multicentre, whole-population, non-concurrent control study using data from the UK National Neonatal Research Database between 1 January 2014 and 31 December 2020. SETTING: Neonatal units in London UK organised by geographical network. PATIENTS: Preterm infants <31 weeks' gestation...
March 4, 2024: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://read.qxmd.com/read/38434697/preliminary-study-on-comparison-of-egg-extraction-methods-for-development-of-fetal-bovine-serum-substitutes-in-cultured-meat
#26
JOURNAL ARTICLE
Da Young Lee, Dahee Han, Seung Yun Lee, Seung Hyeon Yun, Juhyun Lee, Ermie Mariano, Yeongwoo Choi, Jin Soo Kim, Jinmo Park, Sun Jin Hur
Fetal bovine serum (FBS) substitution remains one of the challenges to the realization of cultured meat production in the marketplace. In this study, three methods were developed to extract a substitute for FBS using egg white extract (EWE): using 25 mM CaCl2 /2.5 % ammonium sulfate/citric acid (A); ethyl alcohol (B); and 5 % ammonium sulfate/citric acid (C). B EWE can effectively replace up to 50 % of FBS in growth media (10 % of the total). Ovalbumin in the extracts can promote cell proliferation, and components along the 12 kDa protein band have the potential to inhibit cell proliferation...
March 30, 2024: Food chemistry: X
https://read.qxmd.com/read/38434579/the-fascinating-theory-of-fetal-programming-of-adult-diseases-a-review-of-the-fundamentals-of-the-barker-hypothesis
#27
JOURNAL ARTICLE
Gavino Faa, Vassilios Fanos, Mirko Manchia, Peter Van Eyken, Jasjit S Suri, Luca Saba
The theory of fetal programming of adult diseases was first proposed by David J.P. Barker in the eighties of the previous century, to explain the higher susceptibility of some people toward the development of ischemic heart disease. According to his hypothesis, poor maternal living conditions during gestation represent an important risk factor for the onset of atherosclerotic heart disease later in life. The analysis of the early phases of fetal development is a fundamental tool for the risk stratification of children and adults, allowing the identification of susceptible or resistant subjects to multiple diseases later in life...
January 2024: Journal of Public Health Research
https://read.qxmd.com/read/38432888/clinical-characteristics-of-bronchopulmonary-dysplasia-in-very-preterm-infants
#28
JOURNAL ARTICLE
Yonghui Yang, Xiaori He, Xuefei Zhang, Pingyang Chen
OBJECTIVES: With the development of perinatal and neonatal intensive care medicine, the survival rate of very premature infants increases year by year. However, the incidence of bronchopulmonary dysplasia (BPD) increases year by year, which seriously affects the survival prognosis of very premature infants. How to prevent and treat BPD effectively has become the focus of neonatologists. This study aims to provide ideas for the prevention and treatment of BPD in very preterm infants via analyzing the clinical characteristics of BPD...
October 28, 2023: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://read.qxmd.com/read/38432717/creatine-and-pregnancy-outcomes-a-prospective-cohort-study-of-creatine-metabolism-in-low-risk-pregnant-females
#29
JOURNAL ARTICLE
Deborah L de Guingand, Kirsten R Palmer, Damien L Callahan, Rod J Snow, Miranda L Davies-Tuck, Stacey J Ellery
BACKGROUND: Physiological adaptations during pregnancy alter nutrient and energy metabolism. Creatine may be important for maintaining cellular energy homeostasis throughout pregnancy. However, the impact of pregnancy on endogenous and exogenous creatine availability has never been comprehensively explored. OBJECTIVES: To undertake a prospective cohort study and determine the physiological ranges of creatine and associated metabolites throughout human pregnancy...
March 2024: American Journal of Clinical Nutrition
https://read.qxmd.com/read/38426290/figo-preconception-checklist-preconception-care-for-mother-and-baby
#30
JOURNAL ARTICLE
Chiara Benedetto, Fulvio Borella, Hema Divakar, Sarah L O'Riordan, Martina Mazzoli, Mark Hanson, Sharleen O'Reilly, Bo Jacobsson, Jeanne A Conry, Fionnuala M McAuliffe
The preconception period is a unique and opportunistic time in a woman's life when she is motivated to adopt healthy behaviors that will benefit her and her child, making this time period a critical "window of opportunity" to improve short- and long-term health. Improving preconception health can ultimately improve both fetal and maternal outcomes. Promoting health before conception has several beneficial effects, including an increase in seeking antenatal care and a reduction in neonatal mortality. Preconception health is a broad concept that encompasses the management of chronic diseases, including optimal nutrition, adequate consumption of folic acid, control of body weight, adoption of healthy lifestyles, and receipt of appropriate vaccinations...
March 1, 2024: International Journal of Gynaecology and Obstetrics
https://read.qxmd.com/read/38424158/age-and-sex-based-impacts-of-maternal-iron-deficiency-on-offspring-s-cognitive-function-and-anemia-a-systematic-review
#31
REVIEW
Saudatu Faruk, Kamaldeen Olalekan Sanusi, Kasimu Ghandi Ibrahim, Bilyaminu Abubakar, Ibrahim Malami, Muhammad Bashir Bello, Murtala Bello Abubakar, Abdullahi Yahya Abbas, Mustapha Umar Imam
Iron deficiency is a recognized global health concern, particularly impactful during pregnancy where the mother serves as the primary source of iron for the developing fetus. Adequate maternal iron levels are crucial for fetal growth and cognitive development. This review investigates the correlation between maternal iron deficiency and cognitive impairment and anemia in offspring, considering age and gender differentials. PubMed, ScienceDirect, and Google Scholar databases were queried using keywords "maternal," "iron," "gender/sex," and "cognition...
February 29, 2024: European Journal of Clinical Nutrition
https://read.qxmd.com/read/38417920/anthropometric-biochemical-dietary-morbidity-and-well-being-assessments-in-women-and-children-in-indonesia-india-and-senegal-a-ukri-gcrf-action-against-stunting-hub-protocol-paper
#32
JOURNAL ARTICLE
Hilary Davies-Kershaw, Umi Fahmida, Min Kyaw Htet, Bharati Kulkarni, Babacar Faye, Dwi Yanti, Dewi Shinta, Nur L Zahra, Tiffany C Angelin, Radhika Madhari, Raghu Pullakhandam, Ravindranadh Palika, Teena Dasi, Sylvia Fernandez Rao, Santosh Kumar Banjara, Kiruthika Selvaraj, Dharani Pratyusha Palepu, Dinesh Yadev, Saliou Diouf, Philomene Lopez-Sall, Babacar Diallo, Princillia Mouissi, Sally Fall, Ibrahima Diallo, Aicha Djigal, Tabitha D Van Immerzeel, Fassia Tairou, Assana Diop, Rebecca Pradeilles, Sara Strout, Benjamin Momo Kadia, Darius Tetsa Tata, Modou Lamin Jobarteh, Stephen Allen, Alan Walker, Joanne P Webster, Paul Haggarty, Claire Heffernan, Elaine Ferguson
INTRODUCTION: Child stunting has a complex aetiology, especially in the first 1000 days of life. Nutrition interventions alone have not produced expected impacts in reducing/preventing child stunting, indicating the importance of understanding the complex interplay between environmental, physiological and psychological factors influencing child nutritional status. This study will investigate maternal and child nutrition, health and well-being status and associated factors through the assessment of: (1) anthropometry, (2) biomarkers of nutrition and health status, (3) dietary intakes, (4) fetal growth and development, (5) infant morbidity, (6) infant and young child feeding (IYCF) and (7) perinatal maternal stress, depression and social support...
February 27, 2024: BMJ Paediatrics Open
https://read.qxmd.com/read/38413919/assessment-of-vitamin-status-%C3%A2-a-e-and-d-in-egyptian-neonates-with-iugr-a-cross-sectional-study
#33
JOURNAL ARTICLE
Hanaa Reyad Abdallah, Abderahman A Abdelrazek, Eman Refaat Youness, Hisham A Orban, Marwa A Mahmoud, Ahmed Helal El Sayed, Moushira Zaki
BACKGROUND: Neonates with intrauterine growth retardation (IUGR) may present with fatal complications and permanent serious consequences. Vitamin status may influence fetal development. In this study we assessed vitamin A, E and D concentrations in umbilical cord blood in newborns with IUGR. METHODS: Maternal data were obtained. Neonatal assessment included; age of gestation calculated from last menstrual period, Ultrasound (U/S), new Ballard, Apgar scores and anthropometric measurements including; Head circumference, length and weight...
February 28, 2024: BMC Pediatrics
https://read.qxmd.com/read/38408725/maternal-plasma-phospholipid-polyunsaturated-fatty-acids-in-early-pregnancy-and-thyroid-function-throughout-pregnancy-a-longitudinal-study
#34
JOURNAL ARTICLE
Ling-Jun Li, Ruijin Lu, Shristi Rawal, Anna Birukov, Natalie L Weir, Michael Y Tsai, Jing Wu, Zhen Chen, Cuilin Zhang
BACKGROUND: Evidence has indicated that polyunsaturated fatty acids (PUFAs)-enriched diet could reduce inflammation due to thyroid autoimmunity in vivo, and therefore, enhance thyroid function. OBJECTIVE: We investigated whether early pregnancy plasma phospholipid PUFAs could benefit maternal thyroid function across pregnancy, which is critical to fetal brain development and growth in pregnancy. METHODS: Within the National Institute of Child Health and Human Development (NICHD) Fetal Growth Studies-Singleton Cohort, we collected plasma samples longitudinally from 214 subjects (107 with gestational diabetes mellitus [GDM] matched with 107 controls) with a singleton pregnancy...
February 24, 2024: American Journal of Clinical Nutrition
https://read.qxmd.com/read/38407272/short-communications-one-carbon-metabolite-supplementation-to-nutrient-restricted-beef-heifers-affects-placental-vascularity-during-early-pregnancy
#35
JOURNAL ARTICLE
Chutikun Kanjanaruch, Kerri A Bochantin, Bethania J Dávila Ruiz, Jessica Syring, Yssi Entzie, Layla King, Pawel P Borowicz, Matthew S Crouse, Joel S Caton, Carl R Dahlen, Alison K Ward, Lawrence P Reynolds
We hypothesized that restricted maternal nutrition and supplementation of one-carbon metabolites (OCM; methionine, folate, choline, and vitamin B12) would affect placental vascular development during early pregnancy. A total of 43 cows were bred, and 32 heifers successfully became pregnant with female calves, leading to the formation of four treatment groups: CON - OCM (n=8), CON + OCM (n=7), RES - OCM (n=9), and RES + OCM (n=8). The experimental design was a 2 × 2 factorial, with main factors of dietary intake affecting average daily gain: control (CON; 0...
February 26, 2024: Journal of Animal Science
https://read.qxmd.com/read/38406574/folic-acid-the-key-to-a-healthy-pregnancy-a-prospective-study-on-fetomaternal-outcome
#36
JOURNAL ARTICLE
Madhusudan Dey, Pranjali Dhume, Sanjay K Sharma, Suyash Goel, Sunil Chawla, Ankur Shah, G Madhumidha, Reshu Rawal
OBJECTIVES: The objective of the study is to study the fetomaternal outcome associated with folic acid deficiency in pregnancy. MATERIALS AND METHODS: This hospital-based observational study was conducted in the Department of Obstetrics and Gynaecology at Base Hospital, Delhi Cantt, and a total of 351 participants were enrolled who were fulfilling the inclusion criteria. The plasma folic acid level of the selected patients was measured in the booking visit by automated chemiluminescence assay...
2024: Tzu chi medical journal
https://read.qxmd.com/read/38399604/role-of-nutritional-habits-during-pregnancy-in-the-developing-of-gestational-diabetes-a-single-center-observational-clinical-study
#37
JOURNAL ARTICLE
Jelena Trifunovic-Kubat, Predrag Sazdanovic, Milos Ilic, Djordje Filipovic, Tamara Nikolic Turnic, Sladjana Mihajlovic
(1) Background and Objective : Excessive gestational weight gain is associated with serious complications such as pre-eclampsia, fetal macrosomia and a more frequent need for cesarean section. The aim of this study is to develop a simple screening model that includes maternal age, BMI and nutritive habits in the second trimester in order to predict the risk of GDM in the population of pregnant women in the territory of the Republic of Serbia. (2) Materials and Methods : This single-center, prospective and case-control study was performed in the University Clinical Center "Dr...
February 13, 2024: Medicina
https://read.qxmd.com/read/38398816/metabolomic-biomarkers-of-dietary-approaches-to-stop-hypertension-dash-dietary-patterns-in-pregnant-women
#38
JOURNAL ARTICLE
Liwei Chen, Jin Dai, Guoqi Yu, Wei Wei Pang, Mohammad L Rahman, Xinyue Liu, Oliver Fiehn, Claire Guivarch, Zhen Chen, Cuilin Zhang
Objective: the aim of this study was to identify plasma metabolomic markers of Dietary Approaches to Stop Hypertension (DASH) dietary patterns in pregnant women. Methods: This study included 186 women who had both dietary intake and metabolome measured from a nested case-control study within the NICHD Fetal Growth Studies-Singletons cohort (FGS). Dietary intakes were ascertained at 8-13 gestational weeks (GW) using the Food Frequency Questionnaire (FFQ) and DASH scores were calculated based on eight food and nutrient components...
February 8, 2024: Nutrients
https://read.qxmd.com/read/38398806/dynamics-of-the-gut-microbiota-and-faecal-and-serum-metabolomes-during-pregnancy-a-longitudinal-study
#39
JOURNAL ARTICLE
Ruili Pan, Min Guo, Ying Chen, Guopeng Lin, Peijun Tian, Linlin Wang, Jianxin Zhao, Wei Chen, Gang Wang
Normal pregnancy involves numerous physiological changes, including changes in hormone levels, immune responses, and metabolism. Although several studies have shown that the gut microbiota may have an important role in the progression of pregnancy, these findings have been inconsistent, and the relationship between the gut microbiota and metabolites that change dynamically during and after pregnancy remains to be clarified. In this longitudinal study, we comprehensively profiled the temporal dynamics of the gut microbiota, Bifidobacterium communities, and serum and faecal metabolomes of 31 women during their pregnancies and postpartum periods...
February 7, 2024: Nutrients
https://read.qxmd.com/read/38398801/antenatal-growth-gestational-age-birth-enteral-feeding-and-blood-citrulline-levels-in-very-low-birth-weight-infants
#40
JOURNAL ARTICLE
Midori Obayashi, Sachiko Iwata, Tomoya Okuda, Ichita Mori, Shigeharu Nakane, Yasuko Togawa, Mari Sugimoto, Takao Togawa, Kanji Muramatsu, Shinji Saitoh, Takahiro Sugiura, Osuke Iwata
Early enteral nutrition using reliable biomarkers of intestinal function must be established to improve neurodevelopmental outcomes in very low birth weight infants (VLBWIs). Serum citrulline levels reflect the intestinal function in adults. To elucidate the relationship among antenatal growth, postnatal enteral nutrition, and blood citrulline levels, a retrospective single-center observational study was conducted on 248 VLBWIs born between April 2014 and March 2021. A mixed effect model and post hoc simple slope analysis were used to estimate the correlations between clinical variables and citrulline levels at Early (day 5...
February 7, 2024: Nutrients
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