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https://www.readbyqxmd.com/read/28627837/natural-antioxidant-vitamins-status-in-pregnancies-complicated-with-intrauterine-growth-restriction
#1
Amita K Gadhok, Tarun K Sharma, Maheep Sinha, Rakesh Khunteta, Satish K Vardey, Poonam Sahni, Manisha Sankhla
BACKGROUND: The weight of the infant at birth is a powerful predictor of infant growth and survival and is dependent on maternal health and nutrition during pregnancy. Pregnant women have a defense mechanism against increased oxidative stress composed of antioxidant enzymes and natural antioxidant vitamins like vitamin C and E. Therefore, we evaluated whether differences exist in serum levels of vitamin C and E in pregnant women complicated with intrauterine growth restriction (IUGR)...
May 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/28606217/nutritional-support-for-low-birth-weight-infants-insights-from-animal-studies
#2
Na Li, Wei Wang, Guoyao Wu, Junjun Wang
Infants born with low birth weights (<2500 g, LBW), accounting for about 15 % of newborns, have a high risk for postnatal growth failure and developing the metabolic syndromes such as type 2 diabetes, CVD and obesity later in life. Improper nutrition provision during critical stages, such as undernutrition during the fetal period or overnutrition during the neonatal period, has been an important mediator of these metabolic diseases. Considering the specific physiological status of LBW infants, nutritional intervention and optimisation during early life merit further attention...
June 13, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28599393/hepar-uterinum-a-history-of-ideas-on-fetal-nutrition
#3
Michael Obladen
The means of fetal nutrition has been debated for over two millennia, with the controversy of oral versus parenteral nutrition already in the Corpus Hippocraticum. In 1587 Aranzio rejected connections between maternal and fetal blood vessels, and coined the term "hepar uterinum" for the placenta. From the 16th to the 18th century, a fervent debate focused on the type and extent of connection between maternal and fetal vessels, which was finally settled by Hunter's injection experiment in 1774. But up to the middle of the 19th century, an important nutritive function was attributed to amniotic fluid...
May 24, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28594446/sow-housing-associated-with-reproductive-performance-in-breeding-herds
#4
REVIEW
Yuzo Koketsu, Ryosuke Iida
Female pigs in breeding herds can be managed through four phases-gilt development, breeding, gestation, and lactation-during which they may be housed in group or individual pens, stalls, or on pasture. In this review, we focus on housing environments that optimize outcomes during gestation and lactation. Appropriate housing is important during early gestation, to protect embryos and to confirm pregnancy, and from mid-to-late gestation, to ensure sufficient nutrition to increase placental and fetal growth. No difference in the number of pigs born alive were reported between group housing and individual stall housing, although more risk factors for reproductive performance are associated with group housing than stall housing including genetics, bedding, floor space allowance, group size, social ranking, and parity...
May 2, 2017: Molecular Reproduction and Development
https://www.readbyqxmd.com/read/28592512/higher-maternal-protein-intake-during-pregnancy-is-associated-with-lower-cord-blood-concentrations-of-insulin-like-growth-factor-igf-ii-igf-binding-protein-3-and-insulin-but-not-igf-i-in-a-cohort-of-women-with-high-protein-intake
#5
Karen M Switkowski, Paul F Jacques, Aviva Must, Marie-France Hivert, Abby Fleisch, Matthew W Gillman, Sheryl Rifas-Shiman, Emily Oken
Background: Prenatal exposure to dietary protein may program growth-regulating hormones, consequently influencing early-life growth patterns and later risk of associated chronic diseases. The insulin-like growth factor (IGF) axis is of particular interest in this context given its influence on pre- and postnatal growth and its sensitivity to the early nutritional environment.Objective: Our objective was to examine associations of maternal protein intake during pregnancy with cord blood concentrations of IGF-I, IGF-II, IGF binding protein-3 (IGFBP-3), and insulin...
June 7, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28585842/-inflammatory-bowel-disease-during-pregnancy-and-childbirth
#6
K Závorová
OBJECTIVE: The aim is to give basic information about inflammatory bowel disease (IBD) during pregnancy, to highlight the importance of treatment in pregnancy and also show our own experience with the issue. DESIGN: Original work - a retrospective study. SETTING: Department of Obstetrics and Gynecology, Hospital Hořovice. RESULTS: We provide basic overview information about inheritance, fertility, mutual influence of IBD and pregnancy therapy in pregnancy and childbirth options for patients with IBD...
2017: Ceská Gynekologie
https://www.readbyqxmd.com/read/28580286/role-of-nutrients-and-mtor-signaling-in-the-regulation-of-pancreatic-progenitors-development
#7
Lynda Elghazi, Manuel Blandino-Rosano, Emilyn Alejandro, Corentin Cras-Méneur, Ernesto Bernal-Mizrachi
OBJECTIVE: Poor fetal nutrition increases the risk of type 2 diabetes in the offspring at least in part by reduced embryonic β-cell growth and impaired function. However, it is not entirely clear how fetal nutrients and growth factors impact β-cells during development to alter glucose homeostasis and metabolism later in life. The current experiments aimed to test the impact of fetal nutrients and growth factors on endocrine development and how these signals acting on mTOR signaling regulate β-cell mass and glucose homeostasis...
June 2017: Molecular Metabolism
https://www.readbyqxmd.com/read/28571669/fetal-programming-and-eating-disorder-risk
#8
REVIEW
Candace Jones, Brad Pearce, Ingrid Barrera, Amanda Mummert
Fetal programming describes the process by which environmental stimuli impact fetal development to influence disease development later in life. Our analysis summarizes evidence for the role of fetal programming in eating disorder etiology through review of studies demonstrating specific obstetric complications and later eating risk of anorexia or bulimia. Using Pubmed, we found thirteen studies investigating obstetric factors and eating disorder risk published between 1999 and 2016. We then discuss modifiable maternal risk factors, including nutrition and stress, that influence anorexia or bulimia risk of their offspring...
May 29, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28562247/neurodevelopment-the-impact-of-nutrition-and-inflammation-during-preconception-and-pregnancy-in-low-resource-settings
#9
Betty R Vohr, Elysia Poggi Davis, Christine A Wanke, Nancy F Krebs
The rapid pace of fetal development by far exceeds any other stage of the life span, and thus, environmental influences can profoundly alter the developmental course. Stress during the prenatal period, including malnutrition and inflammation, impact maternal and fetal neurodevelopment with long-term consequences for physical and mental health of both the mother and her child. One primary consequence of maternal malnutrition, inflammation, and other sources of prenatal stress is a poor birth outcome, such as prematurity or growth restriction...
April 2017: Pediatrics
https://www.readbyqxmd.com/read/28562246/assessment-of-neurodevelopment-nutrition-and-inflammation-from-fetal-life-to-adolescence-in-low-resource-settings
#10
Parminder S Suchdev, Michael J Boivin, Brian W Forsyth, Michael K Georgieff, Richard L Guerrant, Charles A Nelson
Efforts to improve child neurodevelopment are critical to health, equity, and sustainable development, particularly in low-resource settings in the United States and globally. The colliding epidemics of food insecurity, infectious diseases, and noncommunicable diseases interact and impact neurodevelopment. Understanding the complex relationships between nutrition, inflammation, and neurodevelopment can inform clinical and public health interventions to improve outcomes. This article reviews key definitions, tools, and considerations for the assessment of nutrition, inflammation, and child neurodevelopment...
April 2017: Pediatrics
https://www.readbyqxmd.com/read/28562245/neurodevelopment-nutrition-and-inflammation-the-evolving-global-child-health-landscape
#11
Zulfiqar A Bhutta, Richard L Guerrant, Charles A Nelson
The last decade has witnessed major reductions in child mortality and a focus on saving lives with key interventions targeting major causes of child deaths, such as neonatal deaths and those due to childhood diarrhea and pneumonia. With the transition to Sustainable Development Goals, the global health community is expanding child health initiatives to address not only the ongoing need for reduced mortality, but also to decrease morbidity and adverse exposures toward improving health and developmental outcomes...
April 2017: Pediatrics
https://www.readbyqxmd.com/read/28561252/general-care-of-the-pregnant-patient-in-the-intensive-care-unit
#12
Timothy M E Crozier
Pregnant women represent a small subset of all intensive care unit (ICU) admissions and may require intensive care for "obstetric" or "nonobstetric" reasons. Women may be admitted to the ICU at any stage of pregnancy or in the postpartum period. Pregnancy may be discovered at the time of admission to the ICU. Pregnancy impacts on ICU care in a variety of ways and requires a multidisciplinary approach to management. Pregnancy is associated with considerable physiological changes that affect most organ systems, including an expansion in blood volume, an increase in minute ventilation, and an increased risk of thrombosis...
April 2017: Seminars in Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28559474/a-low-fat-diet-enriched-in-fish-oil-increased-lipogenesis-and-fetal-outcome-of-c57bl-6-mice
#13
Olatunji A Akerele, Sukhinder K Cheema
There is clear evidence that nutritional strategy employed during pregnancy has profound influence on the offspring health outcomes. However, the effect of the quality and the quantity of maternal fat intake on maternal metabolic profile during different stages of pregnancy and its impact on pregnancy sustainability is not known. Female C57BL/6 mice (7 weeks old) were fed diets varying in the quantity of fat (5% vs 11%) for two weeks prior to mating and throughout pregnancy. The 5% fat diet was enriched with longer chain omega (n)-3 polyunsaturated fatty acids (PUFA) from fish oil...
August 2017: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/28538089/central-hematocrit-levels-in-fetal-malnourished-term-infants
#14
Kerem Ertaş, Özgül Salihoğlu, Emrah Can, Sami Hatipoğlu, Şahin Hamilçikan
BACKROUND: Fetal malnutrition is especially important for common chronic diseases in adult life. They could potentially be prevented by achieving optimal fetal nutrition. OBJECTIVE: The aim of this study was to investigate hematocrit levels of malnourished, term, appropriate for gestational age (AGA) neonates. SUBJECTS AND METHODS: A total of 80 AGA neonates (between 10% and 90% percentiles interval according to birth week), born with spontaneous vaginal delivery between 37 and 42 weeks of gestation, detected by both last menstrual period and ultrasonography measurements, were included in the study...
May 23, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28537579/developmental-origins-of-diabetes-an-indian-perspective
#15
REVIEW
G V Krishnaveni, C S Yajnik
The developmental origins of health disease (DOHaD) hypothesis proposes that altered environmental influences (nutrition, metabolism, pollutants, stress and so on) during critical stages of fetal growth predisposes individuals to diabetes and other non-communicable disease in later life. This phenomenon is thought to reflect permanent effects ('programming') of unbalanced fetal development on physiological systems. Intrauterine programming may underlie the characteristic Indian 'thin-fat' phenotype and the current unprecedented epidemic of diabetes on the backdrop of multigenerational maternal undernutrition in the country...
May 24, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28527301/exploration-of-dietary-patterns-and-alcohol-consumption-in-pregnant-women-in-the-uk-a-mixed-methods-study
#16
Victoria Coathup, Lesley Smith, Mary Boulton
BACKGROUND: fetal Alcohol Spectrum Disorders is a term used to describe a range of physical, cognitive and behavioural deficits in the offspring of women who drank alcohol during pregnancy. A growing body of evidence suggests alcohol consumption in the presence of poor maternal nutrition may increase the risk of harm to the developing fetus. OBJECTIVE: to investigate relationships between maternal dietary patterns and alcohol consumption, and explore which factors influence women's decisions about what to eat and drink during pregnancy...
April 27, 2017: Midwifery
https://www.readbyqxmd.com/read/28523877/mother-nature-in-eczema-maternal-factors-influencing-atopic-dermatitis
#17
REVIEW
Alexandra R Vaughn, Paige Tannhauser, Raja K Sivamani, Vivian Y Shi
Atopic dermatitis (AD) is a highly prevalent chronic inflammatory skin disease. Current knowledge about the etiology of AD suggests that it is multifactorial and involves the interaction of several factors, including environmental triggers, genetics, immunologic factors, and skin barrier dysfunction. The prenatal environment has a significant influence on fetal development, including the maturation of skin barrier function. This review summarizes maternal factors that have been reported to influence the development of AD in offspring, including maternal genetics, nutrition, breastfeeding, environment, and behaviors...
May 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28515164/mrna-levels-of-placental-iron-and-zinc-transporter-genes-are-upregulated-in-gambian-women-with-low-iron-and-zinc-status
#18
Modou Lamin Jobarteh, Harry J McArdle, Grietje Holtrop, Ebrima A Sise, Andrew M Prentice, Sophie E Moore
Background: The role of the placenta in regulating micronutrient transport in response to maternal status is poorly understood.Objective: We investigated the effect of prenatal nutritional supplementation on the regulation of placental iron and zinc transport.Methods: In a randomized trial in rural Gambia [ENID (Early Nutrition and Immune Development)], pregnant women were allocated to 1 of 4 nutritional intervention arms: 1) iron and folic acid (FeFol) tablets (FeFol group); 2) multiple micronutrient (MMN) tablets (MMN group); 3) protein energy (PE) as a lipid-based nutrient supplement (LNS; PE group); and 4) PE and MMN (PE+MMN group) as LNS...
May 17, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28510096/birth-weight-and-its-relation-with-medical-nutrition-therapy-in-gestational-diabetes
#19
Marianne Vestgaard, Allan Stubbe Christensen, Lone Viggers, Finn Friis Lauszus
PURPOSE: The cornerstone in treatment of gestational diabetes mellitus (GDM) is medical nutrition therapy (MNT), but the effect on birth weight is disputed. The birth weight was evaluated with respect to length of MNT and adherence to diet. METHODS: We performed a cohort study on 436 women with GDM and 254 non-diabetic women. Women with a normal oral glucose tolerance test were included as controls as they had similar background predisposition as the women with GDM...
May 16, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28503776/differences-in-dietary-and-lifestyle-habits-between-pregnant-women-with-small-fetuses-and-appropriate-for-gestational-age-fetuses
#20
Maria Dolores Gómez Roig, Edurne Mazarico, Silvia Ferrero, Rocío Montejo, Lourdes Ibáñez, Francisco Grima, Antonio Vela
AIM: The purpose of this study was to determine differences in lifestyle and dietary habits between pregnant women with small for gestational age (SGA) fetuses and those appropriate for gestational age (AGA). METHODS: This cross-sectional, prospective study was conducted over 14 months and included 46 mothers with SGA and 81 with AGA fetuses. Fetal growth was assessed by a routine third trimester scan. Participants completed questionnaires regarding dietary habits, lifestyle behavior and sociodemographic characteristics during the third trimester...
May 15, 2017: Journal of Obstetrics and Gynaecology Research
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