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Traynor M (1999)

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https://www.readbyqxmd.com/read/20400449/level-of-renal-function-in-patients-starting-dialysis-an-era-edta-registry-study
#1
Vianda S Stel, Charles Tomson, David Ansell, Francesco G Casino, Frederic Collart, Patrik Finne, George A Ioannidis, Johan De Meester, Mario Salomone, Jamie P Traynor, Oscar Zurriaga, Kitty J Jager
BACKGROUND: The aims of this European study were (i) to compare the level of renal function at the start of dialysis between age groups, gender, primary renal disease, comorbid conditions, treatment modality, time periods and countries, and (ii) to determine which baseline characteristics are associated with the level of renal function at the start of dialysis. METHODS: Renal registries participating in the European Renal Association-European Dialysis and Transplant Association Registry provided data on serum creatinine 0-4 weeks before the start of dialysis in incident dialysis patients in 1999 and 2003...
October 2010: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/19515803/residual-renal-function-at-the-start-of-dialysis-and-clinical-outcomes
#2
Vianda S Stel, Friedo W Dekker, David Ansell, Hans Augustijn, Francesco G Casino, Frederic Collart, Patrik Finne, George A Ioannidis, Mario Salomone, Jamie P Traynor, Oscar Zurriaga, Enrico Verrina, Kitty J Jager
BACKGROUND: This study evaluates the association between estimated GFR (eGFR) at the start of dialysis and mortality within Europe. METHODS: Renal registries participating in the ERA-EDTA Registry were asked to provide data on serum creatinine recorded 0-4 weeks before the start of dialysis in incident dialysis patients in 1999 and 2003. Within this cohort study, data were available in 11 472 patients from nine national or regional European renal registries. Cox regression analyses were performed to examine the association between GFR estimated by the four-variable MDRD equation (eGFR) and all-cause mortality, using a follow-up through 31 December 2005...
October 2009: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/11181406/genetic-deletion-of-cox-2-prevents-increased-renin-expression-in-response-to-ace-inhibition
#3
H F Cheng, J L Wang, M Z Zhang, S W Wang, J A McKanna, R C Harris
Cyclooxygenase-2 (COX-2) is expressed in macula densa (MD) and surrounding cortical thick ascending limb of the loop of Henle (cTALH) and is involved in regulation of renin production. We and others have previously found that selective COX-2 inhibitors can inhibit renal renin production (Cheng HF, Wang JL, Zhang MZ, Miyazaki Y, Ichikawa I, McKanna JA, and Harris RC. J Clin Invest 103: 953-961, 1999; Harding P, Sigmon DH, Alfie ME, Huang PL, Fishman MC, Beierwaltes WH, and Carretero OA. Hypertension 29: 297-302, 1997; Traynor TR, Smart A, Briggs JP, and Schnermann J...
March 2001: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/10982805/low-chloride-stimulation-of-prostaglandin-e2-release-and-cyclooxygenase-2-expression-in-a-mouse-macula-densa-cell-line
#4
T Yang, J M Park, L Arend, Y Huang, R Topaloglu, A Pasumarthy, H Praetorius, K Spring, J P Briggs, J Schnermann
Reducing luminal NaCl concentration in the macula densa region of the nephron stimulates renin secretion, and this response is blocked by a specific inhibitor of cyclooxygenase-2 (COX-2) (Traynor, T. R., Smart, A., Briggs, J. P., and Schnermann, J. (1999) Am. J. Physiol. Renal Physiol. 277, F706-710). To study whether low NaCl activates COX-2 activity or expression we clonally derived a macula densa cell line (MMDD1 cells) from SV-40 transgenic mice using fluorescence-activated cell sorting of renal tubular cells labeled with segment-specific fluorescent lectins...
December 1, 2000: Journal of Biological Chemistry
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