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National Institute of Health Consensus Conference

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https://www.readbyqxmd.com/read/28639551/facet-joint-injections-for-people-with-persistent-non-specific-low-back-pain-facet-injection-study-a-feasibility-study-for-a-randomised-controlled-trial
#1
David R Ellard, Martin Underwood, Felix Achana, James Hl Antrobus, Shyam Balasubramanian, Sally Brown, Melinda Cairns, James Griffin, Frances Griffiths, Kirstie Haywood, Charles Hutchinson, Ranjit Lall, Stavros Petrou, Nigel Stallard, Colin Tysall, David A Walsh, Harbinder Sandhu
BACKGROUND: The National Institute for Health and Care Excellence (NICE) 2009 guidelines for persistent low back pain (LBP) do not recommend the injection of therapeutic substances into the back as a treatment for LBP because of the absence of evidence for their effectiveness. This feasibility study aimed to provide a stable platform that could be used to evaluate a randomised controlled trial (RCT) on the clinical effectiveness and cost-effectiveness of intra-articular facet joint injections (FJIs) when added to normal care...
May 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28625273/development-of-a-core-outcome-set-for-disease-modification-trials-in-mild-to-moderate-dementia-a-systematic-review-patient-and-public-consultation-and-consensus-recommendations
#2
Lucy Webster, Derek Groskreutz, Anna Grinbergs-Saull, Rob Howard, John T O'Brien, Gail Mountain, Sube Banerjee, Bob Woods, Robert Perneczky, Louise Lafortune, Charlotte Roberts, Jenny McCleery, James Pickett, Frances Bunn, David Challis, Georgina Charlesworth, Katie Featherstone, Chris Fox, Claire Goodman, Roy Jones, Sallie Lamb, Esme Moniz-Cook, Justine Schneider, Sasha Shepperd, Claire Surr, Jo Thompson-Coon, Clive Ballard, Carol Brayne, Orlaith Burke, Alistair Burns, Linda Clare, Peter Garrard, Patrick Kehoe, Peter Passmore, Clive Holmes, Ian Maidment, Fliss Murtagh, Louise Robinson, Gill Livingston
BACKGROUND: There is currently no disease-modifying treatment available to halt or delay the progression of the disease pathology in dementia. An agreed core set of the best-available and most appropriate outcomes for disease modification would facilitate the design of trials and ensure consistency across disease modification trials, as well as making results comparable and meta-analysable in future trials. OBJECTIVES: To agree a set of core outcomes for disease modification trials for mild to moderate dementia with the UK dementia research community and patient and public involvement (PPI)...
May 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28431198/serum-amylase-and-lipase-and-urinary-trypsinogen-and-amylase-for-diagnosis-of-acute-pancreatitis
#3
REVIEW
Gianluca Rompianesi, Angus Hann, Oluyemi Komolafe, Stephen P Pereira, Brian R Davidson, Kurinchi Selvan Gurusamy
BACKGROUND: The treatment of people with acute abdominal pain differs if they have acute pancreatitis. It is important to know the diagnostic accuracy of serum amylase, serum lipase, urinary trypsinogen-2, and urinary amylase for the diagnosis of acute pancreatitis, so that an informed decision can be made as to whether the person with abdominal pain has acute pancreatitis. There is currently no Cochrane review of the diagnostic test accuracy of serum amylase, serum lipase, urinary trypsinogen-2, and urinary amylase for the diagnosis of acute pancreatitis...
April 21, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28404612/systematic-approach-to-evaluating-and-confirming-the-utility-of-a-suite-of-national-health-system-performance-hsp-indicators-in-canada-a-modified-delphi-study
#4
Omid Fekri, Kira Leeb, Yana Gurevich
OBJECTIVES: Evaluating an existing suite of health system performance (HSP) indicators for continued reporting using a systematic criteria-based assessment and national consensus conference. DESIGN: Modified Delphi approach with technical and leadership groups, an online survey of stakeholders and convening a national consensus conference. SETTING: A national health information steward, the Canadian Institute for Health Information (CIHI)...
April 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/28236836/reprint-of-long-term-survivorship-after-hematopoietic-cell-transplantation-roadmap-for-research-and-care
#5
REVIEW
Minoo Battiwalla, André Tichelli, Navneet S Majhail
The number of survivors after hematopoietic cell transplantation (HCT) is expected to dramatically increase over the next decade. Significant and unique challenges confront survivors for decades after their underlying indication (malignancy or marrow failure) has been cured by HCT. The National Institutes of Health (NIH) Late Effects Consensus Conference in June 2016 brought together international experts in the field to plan the next phase of survivorship efforts. Working groups laid out the roadmap for collaborative research and health care delivery...
March 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/28043595/reaching-consensus-on-drug-resistance-conferring-mutations
#6
Daniela M Cirillo, Paolo Miotto, Elisa Tagliani
OBJECTIVE/BACKGROUND: Molecular-based, rapid drug-susceptibility tests are needed to guide the appropriate use of new drugs and new therapeutic regimens at the programmatic level, and to prevent a further increase in the incidence of drug-resistant tuberculosis (TB). Experts have recognized the need for a global, curated, and standardized analysis and data-sharing platform that provides a one-stop data source for clinically relevant genotypic and phenotypic information on Mycobacterium tuberculosis...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/27818318/long-term-survivorship-after-hematopoietic-cell-transplantation-roadmap-for-research-and-care
#7
REVIEW
Minoo Battiwalla, André Tichelli, Navneet S Majhail
The number of survivors after hematopoietic cell transplantation (HCT) is expected to dramatically increase over the next decade. Significant and unique challenges confront survivors for decades after their underlying indication (malignancy or marrow failure) has been cured by HCT. The National Institutes of Health (NIH) Late Effects Consensus Conference in June 2016 brought together international experts in the field to plan the next phase of survivorship efforts. Working groups laid out the roadmap for collaborative research and health care delivery...
February 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/27757807/funding-global-emergency-medicine-research-from-seed-grants-to-nih-support
#8
Bhakti Hansoti, Adam Levine, Latha Ganti, Rockefeller Oteng, Taylor DesRosiers, Payal Modi, Jeremy Brown
BACKGROUND: Funding for global health has grown significantly over the past two decades. Numerous funding opportunities for international development and research work exist; however, they can be difficult to navigate. The 2013 Academic Emergency Medicine consensus conference on global health and emergency care identified the need to strengthen global emergency care research funding, solidify existing funding streams, and expand funding sources. RESULTS: This piece focuses on the various federal funding opportunities available to support emergency physicians conducting international research from seed funding to large institutional grants...
December 2016: International Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27730795/do-legal-issues-deserve-space-in-specialty-medical-journals
#9
Neeraj Nagpal
Physicians and Internists in India have tended to brush under the carpet legal issues affecting their profession. Of concern to all Physicians is the judgment in a recent case where the NCDRC has stated that if MD Medicine Physicians write Physician & Cardiologist on their letterhead it is Quackery. What is MD Medicine degree holder in India qualified and trained to treat ? These are issues which need debate and that can only be initiated once we recognize that there is a problem. Either an MD Medicine is a cardiologist or he is not...
February 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27623692/immunocap%C3%A2-isac-and-microtest-for-multiplex-allergen-testing-in-people-with-difficult-to-manage-allergic-disease-a-systematic-review-and-cost-analysis
#10
Marie Westwood, Bram Ramaekers, Shona Lang, Nigel Armstrong, Caro Noake, Shelley de Kock, Manuela Joore, Johan Severens, Jos Kleijnen
BACKGROUND: Allergy is a form of immune-mediated exaggerated sensitivity (hypersensitivity) to a substance that is either inhaled, swallowed, injected or comes into contact with the skin. Foreign substances that provoke allergies are called allergens. It has been claimed that multiplex allergen testing may help in diagnosing the cause of symptoms in patients with an unclear cause of allergy or who are allergic to more than one substance. OBJECTIVES: To evaluate multiplex allergen testing [devices that can measure the presence of multiple immunoglobulin E (IgE) antibodies in a patient's blood at the same time], by assessing (1) clinical effectiveness (allergy symptoms, incidence of acute exacerbations, mortality, adverse events of testing and treatment, health-care presentations or admissions, health-related quality of life); (2) effects on treatment (diet, immunotherapy medications, other potential testing); (3) any additional diagnostic information provided by multiplex allergen testing; and (4) cost-effectiveness (cost of different assessment strategies)...
September 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27590105/national-institutes-of-health-hematopoietic-cell-transplantation-late-effects-initiative-the-cardiovascular-disease-and-associated-risk-factors-working-group-report
#11
Saro H Armenian, Wassim Chemaitilly, Marcus Chen, Eric J Chow, Christine N Duncan, Lee W Jones, Michael A Pulsipher, Alan T Remaley, Alicia Rovo, Nina Salooja, Minoo Battiwalla
A number of studies have shown that autologous and allogeneic hematopoietic cell transplantation (HCT) contribute to an increased incidence of cardiovascular disease (CVD) and worsening of cardiovascular risk factors that could contribute to further CVD over time. These observations, combined with a notable increase in the number of survivors after HCT in recent years, highlight the need for studies aimed at modifying risk or preventing these outcomes by changing specific approaches and/or post-HCT interventions...
February 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/27453164/consensus-report-of-the-2015-weinman-international-conference-on-mesothelioma
#12
Michele Carbone, Shreya Kanodia, Ann Chao, Aubrey Miller, Anil Wali, David Weissman, Alex Adjei, Francine Baumann, Paolo Boffetta, Brenda Buck, Marc de Perrot, A Umran Dogan, Steve Gavett, Alessandro Gualtieri, Raffit Hassan, Mary Hesdorffer, Fred R Hirsch, David Larson, Weimin Mao, Scott Masten, Harvey I Pass, Julian Peto, Enrico Pira, Ian Steele, Anne Tsao, Gavitt Alida Woodard, Haining Yang, Shakun Malik
On November 9 and 10, 2015, the International Conference on Mesothelioma in Populations Exposed to Naturally Occurring Asbestiform Fibers was held at the University of Hawaii Cancer Center in Honolulu, Hawaii. The meeting was cosponsored by the International Association for the Study of Lung Cancer, and the agenda was designed with significant input from staff at the U.S. National Cancer Institute and National Institute of Environmental Health Sciences. A multidisciplinary group of participants presented updates reflecting a range of disciplinary perspectives, including mineralogy, geology, epidemiology, toxicology, biochemistry, molecular biology, genetics, public health, and clinical oncology...
August 2016: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/27417602/expert-and-advocacy-group-consensus-findings-on-the-horizon-of-public-health-genetic-testing
#13
Stephen M Modell, Karen Greendale, Toby Citrin, Sharon L R Kardia
DESCRIPTION: Among the two leading causes of death in the United States, each responsible for one in every four deaths, heart disease costs Americans $300 billion, while cancer costs Americans $216 billion per year. They also rank among the top three causes of death in Europe and Asia. In 2012 the University of Michigan Center for Public Health and Community Genomics and Genetic Alliance, with the support of the Centers for Disease Control and Prevention Office of Public Health Genomics, hosted a conference in Atlanta, Georgia to consider related action strategies based on public health genomics...
January 27, 2016: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/27211276/updated-web-based-nutrition-management-guideline-for-pku-an-evidence-and-consensus-based-approach
#14
REVIEW
Rani H Singh, Amy C Cunningham, Shideh Mofidi, Teresa D Douglas, Dianne M Frazier, Debra Geary Hook, Laura Jeffers, Helen McCune, Kathryn D Moseley, Beth Ogata, Surekha Pendyal, Jill Skrabal, Patricia L Splett, Adrya Stembridge, Ann Wessel, Frances Rohr
BACKGROUND: In 2014, recommendations for the nutrition management of phenylalanine hydroxylase deficiency were published as a companion to the concurrently published American College of Medical Genetics and Genomics guideline for the medical treatment of phenylketonuria (PKU). These were developed primarily from a summary of findings from the PKU scientific review conference sponsored by the National Institutes of Health and Agency for Healthcare Research & Quality along with additional systematic literature review...
June 2016: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/27174556/a-psychometric-comparison-of-the-clinical-assessment-interview-for-negative-symptoms-and-the-brief-negative-symptom-scale
#15
COMPARATIVE STUDY
Gregory P Strauss, James M Gold
In 2005, the National Institute of Mental Health held a consensus development conference on negative symptoms of schizophrenia. Among the important conclusions of this meeting were that there are at least 5 commonly accepted domains of negative symptoms (blunted affect, alogia, avolition, anhedonia, asociality) and that new rating scales were needed to adequately assess these constructs. Two next-generation negative symptom scales resulted from this meeting: the Brief Negative Symptom Scale (BNSS) and Clinical Assessment Interview for Negative Symptoms (CAINS)...
November 2016: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/26983608/nutrient-reference-value-non-communicable-disease-endpoints-a-conference-report
#16
J R Lupton, J B Blumberg, M L'Abbe, M LeDoux, H B Rice, C von Schacky, A Yaktine, J C Griffiths
Nutrition is complex-and seemingly getting more complicated. Most consumers are familiar with "essential nutrients," e.g., vitamins and minerals, and more recently protein and important amino acids. These essential nutrients have nutrient reference values, referred to as dietary reference intakes (DRIs) developed by consensus committees of scientific experts convened by the Institute of Medicine of the National Academy of Sciences, Engineering, and Medicine and carried out by the Food and Nutrition Board. The DRIs comprise a set of four nutrient-based reverence values, the estimated average requirements, the recommended dietary allowances (RDAs), the adequate intakes and the tolerable upper intake levels for micronutrient intakes and an acceptable macronutrient distribution range for macronutrient intakes...
March 2016: European Journal of Nutrition
https://www.readbyqxmd.com/read/26878229/the-american-academy-of-clinical-neuropsychology-national-academy-of-neuropsychology-and-society-for-clinical-neuropsychology-apa-division-40-2015-tcn-professional-practice-and-salary-survey-professional-practices-beliefs-and-incomes-of-u-s-neuropsychologists
#17
Jerry J Sweet, Laura M Benson, Nathaniel W Nelson, Paul J Moberg
OBJECTIVE: The current survey updated professional practice and income information pertaining to clinical neuropsychology. METHODS: Doctoral-level members of the American Academy of Clinical Neuropsychology, Division 40 (Clinical Neuropsychology) of the American Psychological Association, and the National Academy of Neuropsychology and other neuropsychologists, as well as postdoctoral trainees in the Association of Postdoctoral Programs in Clinical Neuropsychology and at other training sites were invited to participate in a web-based survey in early 2015...
2015: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/26598829/osteoporosis-and-lifestyle
#18
Yoshiko Ishimi
Skeletal tissue is formed during the first two decades of life; then a constant bone mass is maintained until 40 y of age. In the case of women, the bone mass is rapidly reduced at menopause at around 50 y of age. After that, bone mass slowly decreases in both men and women who have passed the 70-y-old mark. The National Institute of Health Consensus Conference adopted the definition of osteoporosis as a skeletal disorder that is characterized by compromised bone strength leading to a predisposition for and an increased risk of fracture...
2015: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/26596705/undiagnosed-diseases-network-international-udni-white-paper-for-global-actions-to-meet-patient-needs
#19
Domenica Taruscio, Stephen C Groft, Helene Cederroth, Béla Melegh, Paul Lasko, Kenjiro Kosaki, Gareth Baynam, Alexa McCray, William A Gahl
In 2008, the National Institutes of Health's (NIH) Undiagnosed Disease Program (UDP) was initiated to provide diagnoses for individuals who had long sought one without success. As a result of two international conferences (Rome 2014 and Budapest 2015), the Undiagnosed Diseases Network International (UDNI) was established, modeled in part after the NIH UDP. Undiagnosed diseases are a global health issue, calling for an international scientific and healthcare effort. To meet this demand, the UDNI has built a consensus framework of principles, best practices and governance; the Board of Directors reflects its international character, as it includes experts from Australia, Canada, Hungary, Italy, Japan and the USA...
December 2015: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/26567519/funding-research-in-emergency-diagnostic-imaging-summary-of-a-panel%C3%A2-discussion-at-the-2015-academic-emergency-medicine-consensus-conference
#20
Alan R Cherney, Jennifer R Marin, Jeremy Brown, Ayodola Anise, Steven Krosnick, Kerm Henriksen, Roger J Lewis, Angela M Mills
As part of the 2015 Academic Emergency Medicine consensus conference "Diagnostic Imaging in the Emergency Department: A Research Agenda to Optimize Utilization," a panel of representatives from the National Institute of Health's Office of Emergency Care Research, the National Institute of Biomedical Imaging and Bioengineering, the Agency for Healthcare Research and Quality, and the Patient-Centered Outcomes Research Institute was assembled to discuss future opportunities for funding research in this particular area of interest...
December 2015: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
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