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the effect of sleep deprivation

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https://www.readbyqxmd.com/read/28810965/the-benefits-and-risks-of-energy-drinks-in-young-adults-and-military-service-members
#1
Julianne Manchester, Inbal Eshel, Donald W Marion
INTRODUCTION: Energy drinks (EDs) have become an integral part of the young adult, athletic, and military culture. Many athletes are convinced that EDs enhance performance, and service members as well as college students frequently use EDs as stimulants to counter sleep deprivation, or to improve academic performance. However, concerns have been raised by some military leaders about potential adverse effects of EDs. MATERIALS AND METHODS: A needs assessment survey of a convenience sample of military health care providers was conducted and identified EDs as a top knowledge need for those providers working in the area of traumatic brain injury (TBI)...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28809932/rem-sleep-deprivation-induces-endothelial-dysfunction-and-hypertension-in-middle-aged-rats-roles-of-the-enos-no-cgmp-pathway-and-supplementation-with-l-arginine
#2
Jiaye Jiang, Zhongyuan Gan, Yuan Li, Wenqi Zhao, Hanqing Li, Jian-Pu Zheng, Yan Ke
Sleep loss can induce or aggravate the development of cardiovascular and cerebrovascular diseases. However, the molecular mechanism underlying this phenomenon is poorly understood. The present study was designed to investigate the effects of REM sleep deprivation on blood pressure in rats and the underlying mechanisms of these effects. After Sprague-Dawley rats were subjected to REM sleep deprivation for 5 days, their blood pressures and endothelial function were measured. In addition, one group of rats was given continuous access to L-arginine supplementation (2% in distilled water) for the 5 days before and the 5 days of REM sleep deprivation to reverse sleep deprivation-induced pathological changes...
2017: PloS One
https://www.readbyqxmd.com/read/28803119/the-effects-of-low-intensity-cycling-on-cognitive-performance-following-sleep-deprivation
#3
Alexis B Slutsky, Jed A Diekfuss, James A Janssen, Nate T Berry, Chia-Hao Shih, Louisa D Raisbeck, Laurie Wideman, Jennifer L Etnier
This study examined the effect of 24h of sleep deprivation on cognitive performance and assessed the effect of acute exercise on cognitive performance following sleep deprivation. Young, active, healthy adults (n=24, 14 males) were randomized to control (age=24.7±3.7years, BMI=27.2±7.0) or exercise (age=25.3±3.3years, BMI=25.6±5.1) groups. Cognitive testing included a 5-min psychomotor vigilance task (PVT), three memory tasks with increasing cognitive load, and performance of the PVT a second time. On morning one, cognitive testing followed a typical night's sleep...
August 9, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28782143/dynamics-of-cerebral-responses-to-sustained-attention-performance-during-one-night-of-sleep-deprivation
#4
Yuanqiang Zhu, Yibin Xi, Ningbo Fei, Yuchen Liu, Xinxin Zhang, Lin Liu, Ziliang Xu, Jinbo Sun, Xuejuan Yang, Hong Yin, Jie Tian, Wei Qin
Total sleep deprivation (TSD) is increasingly common in modern society bringing various neurobehavioural effects. Dynamic changes of behaviour performances during TSD have been reported extensively, while the cerebral activation underlying such changes have not been elucidated clearly. This study aimed to investigate dynamic changes in cerebral responses to the fastest and slowest psychomotor vigilance task (PVT) trials during TSD. Thirty-six healthy subjects with intermediate chronotype performed the PVT while undergoing functional magnetic resonance imaging every 2 h from 22:00 hours on the first day to 06:00 hours on the second day (i...
August 6, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28774856/modafinil-improves-attentional-performance-in-healthy-non-sleep-deprived-humans-at-doses-not-inducing-hyperarousal-across-species
#5
Zackary A Cope, Arpi Minassian, Dustin Kreitner, David A MacQueen, Morgane Milienne-Petiot, Mark A Geyer, William Perry, Jared W Young
The wake-promoting drug modafinil is frequently used off-label to improve cognition in psychiatric and academic populations alike. The domain-specific attentional benefits of modafinil have yet to be quantified objectively in healthy human volunteers using tasks validated for comparison across species. Further, given that modafinil is a low-affinity inhibitor for the dopamine and norepinephrine transporters (DAT/NET respectively) it is unclear if any effects are attributable to a non-specific increase in arousal, a feature of many catecholamine reuptake inhibitors (e...
August 1, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28760549/cognitive-deficits-in-obstructive-sleep-apnea-insights-from-a-meta-review-and-comparison-with-deficits-observed-in-copd-insomnia-and-sleep-deprivation
#6
REVIEW
Michelle Olaithe, Romola S Bucks, David R Hillman, Peter R Eastwood
Obstructive sleep apnea (OSA) is a nocturnal breathing disorder that is associated with cognitive impairment. The primary determinants of cognitive deficits in OSA are thought to be sleep disruption and blood gas abnormalities. Cognitive impairment is also seen in other disorders that are characterised primarily by sleep disturbance (e.g., sleep restriction/deprivation, insomnia) or hypoxia/hypercarbia (e.g., chronic obstructive pulmonary disease (COPD)). Assessment of the cognitive deficits observed in these other disorders could help better define the mechanisms underlying cognitive deficits in OSA...
March 30, 2017: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/28741085/the-effect-of-sleep-deprivation-on-retrieval-of-emotional-memory-a-behavioural-study-using-film-stimuli
#7
Daniela Tempesta, Valentina Socci, Giada Dello Ioio, Luigi De Gennaro, Michele Ferrara
Although the deleterious effects of sleep deprivation on memory consolidation are well documented, it is still unclear how the facilitating effect of emotions on memory consolidation processes could be modulated by the lack of sleep. In this study, we investigated the effects of sleep deprivation on episodic memory using emotional and non-emotional film stimuli. Forty-eight healthy subjects, divided into a sleep group (SG) and a sleep-deprived (SD) group, completed an Encoding and a Recall phase. Participants in the SD group were sleep deprived the night immediately following the Encoding phase, whereas the control group slept at home...
July 24, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28732645/sleep-deprivation-predisposes-allergic-mice-to-develop-neutrophilic-lung-inflammation
#8
Jethe Nunes de Oliveira Filho, Juliana de Souza Apostolico, David Anibal Garrido Andrade, Francieli Ruiz da Silva, Edgar Ruz Fernandes, Monica Levy Andersen, Alexandre Castro Keller, Daniela Santoro Rosa
BACKGROUND: Although different studies associated sleep deprivation with systemic inflammatory changes, the effect of sleep duration on the pathology of allergic chronic diseases is poorly understood. OBJECTIVE: To evaluate the influence of sleep deprivation on allergen-induced pulmonary inflammation. METHODS: Ovalbumin (OVA)-sensitized C57BL/6 mice were exposed to a first set of intranasal OVA challenge under sleep deprivation (SD) or healthy sleep (HS) conditions followed by a second OVA challenge, one week apart...
July 18, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28726307/naturally-occurring-circadian-rhythm-and-sleep-duration-are-related-to-executive-functions-in-early-adulthood
#9
Liisa Kuula, Anu-Katriina Pesonen, Kati Heinonen, Eero Kajantie, Johan Gunnar Eriksson, Sture Andersson, Aulikki Lano, Jari Lahti, Dieter Wolke, Katri Räikkönen
Experimental sleep deprivation studies suggest that insufficient sleep and circadian misalignment associates with poorer executive function. It is not known whether this association translates to naturally occurring sleep patterns. A total of 512 of full-term-born members of the Arvo Ylppö Longitudinal Study [mean age = 25.3, standard deviation (SD) = 0.65] (44.3% men) wore actigraphs to define sleep duration, its irregularity and circadian rhythm (sleep mid-point) during a 1-week period (mean 6.9 nights, SD = 1...
July 20, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28714081/combining-two-model-systems-of-psychosis-the-effects-of-schizotypy-and-sleep-deprivation-on-oculomotor-control-and-psychotomimetic-states
#10
Inga Meyhöfer, Maria Steffens, Eliana Faiola, Anna-Maria Kasparbauer, Veena Kumari, Ulrich Ettinger
Model systems of psychosis, such as schizotypy or sleep deprivation, are valuable in informing our understanding of the etiology of the disorder and aiding the development of new treatments. Schizophrenia patients, high schizotypes, and sleep-deprived subjects are known to share deficits in oculomotor biomarkers. Here, we aimed to further validate the schizotypy and sleep deprivation models and investigated, for the first time, their interactive effects on smooth pursuit eye movements (SPEM), prosaccades, antisaccades, predictive saccades, and measures of psychotomimetic states, anxiety, depression, and stress...
July 17, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28707310/sleep-deprivation-in-interventional-cardiology-implications-for-patient-care-and-physician-health
#11
Yader Sandoval, Angie S Lobo, Virend K Somers, Kenneth Rosenfield, Steven M Bradley, Paul Sorajja, Peter Tajti, Emmanouil S Brilakis
The burden and impact of sleep deprivation on both patient care and on the health of interventional cardiologists is not well understood. Due to the nature of emergent procedures occurring in the cardiac catheterization laboratory, interventionalists are prone to suffer from acute and/or chronic sleep deprivation. Sleep deprivation has been associated with numerous adverse effects, such as impaired performance, cognitive deficits, reduced psychomotor vigilance, and workplace errors and injuries, among many others...
July 14, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28694754/using-curcumin-to-prevent-structural-and-behavioral-changes-of-medial-prefrontal-cortex-induced-by-sleep-deprivation-in-rats
#12
Ali Noorafshan, Fatemeh Karimi, Saied Karbalay-Doust, Ali Mohammad Kamali
Sleep Deprivation (SD) is known to result in a range of neurological consequences in chronically-afflicted subjects. Curcumin, a natural substance, has neuroprotective properties. This study aimed to evaluate the effects of curcumin on the medial Prefrontal Cortex (mPFC) of SD rats. Male rats were arbitrarily assigned to nine groups, including control, curcumin (100 mg/kg/day), olive oil, SD, SD+curcumin, SD+olive oil, grid, grid+curcumin, and grid+olive oil groups. SD was induced by a multiplatform box containing water...
2017: EXCLI journal
https://www.readbyqxmd.com/read/28694098/sleep-promoting-potential-of-low-dose-%C3%AE-asarone-in-rat-model
#13
Arathi Radhakrishnan, N Jayakumari, Velayudhan Mohan Kumar, Kamalesh K Gulia
Commonly used hypnotics have undesirable side-effects, especially during continuous usage. On the other hand, some herbal products, which are used for prolonged periods, are suggested to have a sleep inducing property, though the claims have not been validated scientifically. The hypnotic potential of α-Asarone, an active principle of Acorus species, was tested in the present study by first identifying the optimal dose of α-Asarone for improving sleep, followed by studies that evaluated the effect of repeated administration of this optimal dose for five days on sleep deprived rats...
July 8, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28680341/effects-of-sleep-deprivation-on-cognitive-and-physical-performance-in-university-students
#14
Yusuf Patrick, Alice Lee, Oishik Raha, Kavya Pillai, Shubham Gupta, Sonika Sethi, Felicite Mukeshimana, Lothaire Gerard, Mohammad U Moghal, Sohag N Saleh, Susan F Smith, Mary J Morrell, James Moss
Sleep deprivation is common among university students, and has been associated with poor academic performance and physical dysfunction. However, current literature has a narrow focus in regard to domains tested, this study aimed to investigate the effects of a night of sleep deprivation on cognitive and physical performance in students. A randomized controlled crossover study was carried out with 64 participants [58% male (n = 37); 22 ± 4 years old (mean ± SD)]. Participants were randomized into two conditions: normal sleep or one night sleep deprivation...
2017: Sleep and Biological Rhythms
https://www.readbyqxmd.com/read/28677325/memory-encoding-is-impaired-after-multiple-nights-of-partial-sleep-restriction
#15
James N Cousins, Karen Sasmita, Michael W L Chee
Sleep is important for normative cognitive functioning. A single night of total sleep deprivation can reduce the capacity to encode new memories. However, it is unclear how sleep restriction during several consecutive nights affects memory encoding. To explore this, we employed a parallel-group design with 59 adolescents randomized into sleep-restricted (SR) and control groups. Both groups were afforded 9 h time in bed (TIB) for 2 baseline nights, followed by 5 consecutive nights of 5 h TIB for the SR group (n = 29) and 9 h TIB for the control group (n = 30)...
July 5, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28676829/changes-in-body-water-caused-by-sleep-deprivation-in-taeeum-and-soyang-types-in-sasang-medicine-prospective-intervention-study
#16
Seung Min Hong, Byung Joo Kim, Seungwon Shin, Minwoo Hwang
BACKGROUND: There is a negative relationship between sleep deprivation and health. However, no study has investigated the effect of sleep deprivation on individuals with different body composition. The aim of this study was to determine the differential effect of sleep deprivation in individuals with different body compositions (fluid) according to Soyang type (SY) and Taeeum type (TE). METHODS: Sixty-two cognitively normal, middle-aged people with normal sleep patterns were recruited from the local population...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28676763/sleep-deprivation-in-young-and-healthy-subjects-is-more-sensitively-identified-by-higher-frequencies-of-electrodermal-activity-than-by-skin-conductance-level-evaluated-in-the-time-domain
#17
Hugo F Posada-Quintero, Jeffrey B Bolkhovsky, Natasa Reljin, Ki H Chon
We analyzed multiple measures of the autonomic nervous system (ANS) based on electrodermal activity (EDA) and heart rate variability (HRV) for young healthy subjects undergoing 24-h sleep deprivation. In this study, we have utilized the error awareness test (EAT) every 2 h (13 runs total), to evaluate the deterioration of performance. EAT consists of trials where the subject is presented words representing colors. Subjects are instructed to press a button ("Go" trials) or withhold the response if the word presented and the color of the word mismatch ("Stroop No-Go" trial), or the screen is repeated ("Repeat No-Go" trials)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28670970/the-effect-of-monocular-deprivation-on-unihemispheric-sleep-in-light-and-dark-incubated-reared-domestic-chicks
#18
Angelica Quercia, Daniela Bobbo, Gian Gastone Mascetti
Unihemispheric sleep is an aspect of the cerebral lateralization of certain species of birds. During sleep, domestic chicks (Gallus gallus) show brief periods of monocular-unihemispheric sleep (Mo-Un sleep): one eye is open and the connected hemisphere is awaken while the other eye remains shut and the connected hemisphere sleeps. The time spent in Mo-Un sleep was investigated following a brief monocular deprivation (MD) in chicks hatched from eggs incubated in darkness and reared in light (D-L), incubated in light and reared in light (L-L) and incubated in darkness and reared in darkness (D-D)...
July 2, 2017: Laterality
https://www.readbyqxmd.com/read/28670711/later-school-start-times-for-supporting-the-education-health-and-well-being-of-high-school-students
#19
REVIEW
Robert Marx, Emily E Tanner-Smith, Colleen M Davison, Lee-Anne Ufholz, John Freeman, Ravi Shankar, Lisa Newton, Robert S Brown, Alyssa S Parpia, Ioana Cozma, Shawn Hendrikx
BACKGROUND: A number of school systems worldwide have proposed and implemented later school start times as a means of avoiding the potentially negative impacts that early morning schedules can have on adolescent students. Even mild sleep deprivation has been associated with significant health and educational concerns: increased risk for accidents and injuries, impaired learning, aggression, memory loss, poor self-esteem, and changes in metabolism. Although researchers have begun to explore the effects of delayed school start time, no one has conducted a rigorous review of evidence to determine whether later school start times support adolescent health, education, and well-being...
July 3, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28668380/sleep-deprivation-induces-changes-in-5-ht-actions-and-5-ht1a-receptor-expression-in-the-rat-hippocampus
#20
H Azizi, J Hwang, V Suen, N Z Kang, R Somvanshi, R Tadavarty, U Kumar, B R Sastry
A 12h sleep deprivation enhances the expression of 5-hydroxytryptamine (5-HT) 1A receptors in rat hippocampus that recedes with 48h sleep recovery. The depressant effect of applied 5-HT on the field excitatory postsynaptic potentials recorded in the CA1 area, is also enhanced in hippocampi of SD rats. Following a 24 or 48h sleep recovery, the increase in the 5-HT effect subsided. These results have implications for therapeutics treating clinical depression.
August 10, 2017: Neuroscience Letters
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