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the effect of sleep deprivation

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https://www.readbyqxmd.com/read/29790961/increased-vulnerability-to-attentional-failure-during-acute-sleep-deprivation-in-women-depends-on-menstrual-phase
#1
Parisa Vidafar, Joshua J Gooley, Angus C Burns, Shantha M W Rajaratnam, Melanie Rueger, Eliza Van Reen, Charles A Czeisler, Steven W Lockley, Sean W Cain
Study Objectives: Investigate sex differences in the effect of sleep deprivation on performance, accounting for menstrual phase in women. Methods: We examined alertness data from 124 healthy women and men (40 women, 84 men; aged 18 - 30 years) who maintained wakefulness for at least 30 hours in a laboratory setting using a constant routine protocol. Objective alertness was assessed every two hours using a 10-minute Psychomotor Vigilance Task. Subjective alertness was assessed every hour via the Karolinska Sleepiness Scale...
May 22, 2018: Sleep
https://www.readbyqxmd.com/read/29775085/usage-of-therapeutic-sleep-deprivation-a-survey-in-psychiatric-hospitals-in-austria-germany-and-switzerland
#2
Dietmar Winkler, Marie Spies, Yasmin Al-Resheg, Joseph C Wu, William E Bunney, Blynn G Bunney, Siegfried Kasper, Edda Pjrek
OBJECTIVE: Therapeutic sleep deprivation (SD) is a nonpharmacological treatment that is used most often for depression. The aim of this study was to examine the pattern of use of SD in psychiatric hospitals in Austria, Germany, and Switzerland. METHODS: A questionnaire about perceived usage of SD was sent by mail to all 511 psychiatric hospitals in the three countries. Nonresponders were asked to answer the questionnaire by phone. We achieved a response rate of 75...
May 18, 2018: Behavioral Sleep Medicine
https://www.readbyqxmd.com/read/29748772/decreased-cortical-and-subcortical-response-to-inhibition-control-after-sleep-deprivation
#3
Rui Zhao, Xinxin Zhang, Ningbo Fei, Yuanqiang Zhu, Jinbo Sun, Peng Liu, Xuejuan Yang, Wei Qin
The effects of sleep deprivation (SD) on the neural substrates of inhibition control are poorly understood. Here we used functional magnetic resonance imaging to examine the effects of 24 h of SD on cerebral activation during a stop-signal task in 20 normal young subjects. Behaviorally, subjects showed significantly delayed stop-signal reaction time (SSRT) following SD. In addition, reduced cerebral activation was found in the "stopping network" (including the inferior frontal gyrus [IFG], supplementary motor area, subthalamic nucleus [STN] and insula) and vision-related regions (occipital cortex, lingual gyrus and fusiform gyrus) after SD...
May 10, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29746721/melatonin-for-the-promotion-of-sleep-in-adults-in-the-intensive-care-unit
#4
REVIEW
Sharon R Lewis, Michael W Pritchard, Oliver J Schofield-Robinson, Phil Alderson, Andrew F Smith
BACKGROUND: Patients in the intensive care unit (ICU) experience sleep deprivation caused by environmental disruption, such as high noise levels and 24-hour lighting, as well as increased patient care activities and invasive monitoring as part of their care. Sleep deprivation affects physical and psychological health, and patients perceive the quality of their sleep to be poor whilst in the ICU. Artificial lighting during night-time hours in the ICU may contribute to reduced production of melatonin in critically ill patients...
May 10, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29741724/myelin-modifications-after-chronic-sleep-loss-in-adolescent-mice
#5
Michele Bellesi, John Douglas Haswell, Luisa de Vivo, William Marshall, Patrick H Roseboom, Giulio Tononi, Chiara Cirelli
Study Objectives: Previous studies found that sleep loss can suppress the expression of genes implicated in myelination and can have adverse effects on oligodendrocyte precursor cells. On the other hand, sleep may favor myelination by promoting the expression of genes involved in its formation and maintenance. Albeit limited, these results suggest that sleep loss can have detrimental effects on the formation and maintenance of myelin. Methods: Here, we tested this hypothesis by evaluating ultrastructural modifications of myelin in two brain regions (corpus callosum and lateral olfactory tract) of mice exposed to different periods of sleep loss, from a few hours of sleep deprivation to ~5 days of chronic sleep restriction...
May 1, 2018: Sleep
https://www.readbyqxmd.com/read/29737605/chronic-high-caloric-diet-modifies-sleep-homeostasis-in-mice
#6
Maria Panagiotou, Johanna H Meijer, Tom Deboer
Obesity prevalence and sleep habit changes are commonplace nowadays, due to modern lifestyle. A bidirectional relationship likely exists between sleep quality and metabolic disruptions, that could impact quality of life. In our study, we investigated the effects of a chronic high-caloric diet on sleep architecture and sleep regulation in mice. We studied the effect of three months high-caloric diet (HCD, 45% fat) on sleep and the sleep electroencephalogram (EEG) in C57BL/6J mice during 24-h baseline (BL) recordings, and after 6-h sleep deprivation (SD)...
May 8, 2018: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29734983/the-effects-of-experimental-sleep-fragmentation-and-sleep-deprivation-on-the-response-of-the-genioglossus-muscle-to-inspiratory-resistive-loads
#7
Jennifer M Cori, Christian L Nicholas, Joanne Avraam, V Vien Lee, Rachel Schembri, Melinda L Jackson, Amy S Jordan
STUDY OBJECTIVES: Poor upper airway dilator muscle function may contribute to obstructive sleep apnea (OSA). Sleep deprivation reduces dilator muscle responsiveness, but sleep fragmentation, which is most characteristic of OSA, has not been assessed. This study compared the effects of sleep deprivation and fragmentation on dilator muscle responsiveness during wakefulness. METHOD: Twenty-four healthy individuals (10 female) participated in two consecutive overnight polysomnography (PSG) sessions...
April 30, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29727778/differences-in-sensory-reweighting-due-to-loss-of-visual-and-proprioceptive-cues-in-postural-stability-support-among-sleep-deprived-cadet-pilots
#8
Shan Cheng, Jin Ma, Jicheng Sun, Jian Wang, Xiao Xiao, Yihan Wang, Wendong Hu
BACKGROUND: Sleep deprivation is known to diminish postural control. RESEARCH QUESTION: We investigated whether sleep deprivation affects sensory reweighting for postural control due to loss of visual and proprioceptive cues. METHODS: Two cohorts of cadet pilots were deprived of sleep for 40 h. Variabilty in force-platform center of pressure was analyzed based on the whole path length (WPL); circumference area (CA); mean of displacement along x and y axes and corresponding standard deviations (SDx, SDy); and frequency of body-sway intensity, all of which were recorded while the cadets stood with eyes open (NEO), eyes closed (NEC), and eyes closed on a foam platform base (FEC) A sleepiness index (SUBI) based on principal component analysis of selected Cohort 1 data (n = 37) was used to compare Cohort 2 data (n = 29) with scores for the Stanford Sleepiness Scale (SSS) and Pittsburg Sleep Quality Index (PSQI)...
April 26, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29726694/the-role-of-the-nervous-system-in-neuromuscular-fatigue-induced-by-ultra-endurance-exercise
#9
Guillaume Y Millet, Vincent Martin, John Temesi
Ultra-endurance events are not a recent development but they have only become very popular in the last two decades, particularly ultra-marathons run on trails. The present paper reviews the role of the central nervous system (CNS) in neuromuscular fatigue induced by ultra-endurance exercise. Large decreases in voluntary activation are systematically found in ultra-endurance running but are attenuated in ultra-endurance cycling for comparable intensity and duration. This indirectly suggests that afferent feedback, rather than neurobiological changes within the CNS, is determinant in the amount of central fatigue produced...
May 4, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29722893/response-to-chronic-sleep-restriction-extension-and-total-sleep-deprivation-in-humans-adaptation-or-preserved-sleep-homeostasis
#10
Jelena Skorucak, Emma Arbon, Derk-Jan Dijk, Peter Achermann
Sleep is regulated by a homeostatic process which in the two-process model of human sleep regulation is represented by EEG slow-wave activity (SWA). Many studies of acute manipulation of wake duration have confirmed the precise homeostatic regulation of SWA in rodents and humans. However, some chronic sleep restriction studies in rodents show that the sleep homeostatic response, as indexed by SWA, is absent or diminishes suggesting adaptation occurs. Here, we investigate the response to 7 days of sleep restriction (6 h time in bed) and extension (10 h time in bed) as well as the response to subsequent total sleep deprivation in 35 healthy participants in a cross-over design...
May 2, 2018: Sleep
https://www.readbyqxmd.com/read/29721652/a-preliminary-evaluation-of-a-school-based-media-education-and-reduction-intervention
#11
David S Bickham, Yulin Hswen, Ronald G Slaby, Michael Rich
While media education and reduction programs have been proposed to prevent adverse health and academic outcomes related to heavy electronic media use among school-aged children, few have been formally piloted and evaluated. We used a quasi-experimental design to evaluate the effectiveness of Take the Challenge (TtC), a school-based media education/reduction program for the primary prevention of sleep deprivation, dysfunctional social-emotional behaviors, and poor academic performance. Sixth- to eighth-grade students at a rural Midwestern U...
May 2, 2018: Journal of Primary Prevention
https://www.readbyqxmd.com/read/29709569/the-effect-of-sleep-deprivation-on-emotional-memory-consolidation-in-participants-reporting-depressive-symptoms
#12
Marcus O Harrington, Karen M Nedberge, Simon J Durrant
Sleep has been shown to play a crucial role in the consolidation of emotionally salient memories. However, the influence of sleep, and Sleep Deprivation (SD), on emotional memory consolidation in depressive individuals remains elusive. For this experiment we recruited two groups of healthy students, one reporting mild-to-severe depressive symptoms, and another reporting minimal/no depressive symptoms (assessed using the Beck Depression Inventory; BDI-II). We measured recognition performance for positive, neutral and negative images before and after a 12 h overnight retention interval, during which participants either remained awake in the laboratory or returned home to sleep normally...
April 27, 2018: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/29705475/the-effects-of-reflexology-on-pain-and-sleep-deprivation-in-patients-with-rheumatoid-arthritis-a-randomized-controlled-trial
#13
Ercan Bakir, Sevgin Samancioglu Baglama, Savas Gursoy
OBJECTIVE: This study was intended to examine the effect of foot reflexology on RA patients' pain and sleep quality. METHODS: This is a randomized controlled trial and was held at the "Rheumatology Follow-up Polyclinic" in Turkey between January-July 2015. A total of 60 patients were included in the research. A sociodemographic data form, the Pittsburgh Sleep Quality Index (PSQI) and the Visual Analogue Scale (VAS) were used. Foot Reflexology was administered to the experimental group...
May 2018: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/29687266/physiological-and-psychological-determinants-of-whole-body-endurance-exercise-following-short-term-sustained-operations-with-partial-sleep-deprivation
#14
Michail E Keramidas, Magnus Gadefors, Lars-Ove Nilsson, Ola Eiken
PURPOSE: The study examined the effects of short-term field-based military training with partial sleep deprivation on whole-body endurance performance in well-trained individuals. METHODS: Before and after a 2-day sustained operations (SUSOPS), 14 cadets performed a 15-min constant-load cycling at 65% of peak power output (PPO; CLT65 ), followed by an exhaustive constant-load trial at 85% of PPO (CLT85 ). Physiological [oxygen uptake ([Formula: see text]O2 ), heart rate (HR), mean arterial pressure (MAP), cardiac output (CO), and regional oxygenation (TOI) in the frontal cerebral cortex and vastus lateralis muscle] and psychological [effort perception (RPE), affective valence (FS), and perceived activation (FAS)] variables were monitored during exercise...
April 23, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29680789/neurophysiological-differences-in-the-adolescent-brain-following-a-single-night-of-restricted-sleep-a-7t-fmri-study
#15
Jennifer L Robinson, Stephen A Erath, Rajesh K Kana, Mona El-Sheikh
Sleep deprivation in youth has garnered international attention in recent years, as correlational studies have demonstrated significant relationships between lack of sleep and detrimental behavioral and academic outcomes. However, no study to date has systematically examined the neurophysiological consequences of a single night of sleep restriction (i.e., 4 h) in adolescents using ultra-high field functional neuroimaging. Much of what we know regarding the neural consequences of sleep deprivation has come from the adult literature, and among those studies, the majority use region of interest (ROI) approaches, thus disregarding the dynamic mechanisms that may subserve the behavioral effects of sleep restriction...
April 7, 2018: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/29680249/24-hour-sleep-deprivation-impairs-early-attentional-modulation-of-neural-processing-an-event-related-brain-potential-study
#16
Eve Wiggins, Malayka Mottarella, Kendra Good, Seth Eggleston, Courtney Stevens
Prior research indicates sleep deprivation negatively impacts selective attention, although less is known about the neural bases of these effects. The present study used event-related brain potentials (ERPs) to examine whether the effects of total sleep deprivation could be traced to the earliest stages of sensory processing influenced by selective attention. Participants were randomly assigned either to a regular sleep or 24-hour total sleep deprivation condition. Following either sleep deprivation or regular sleep, participants completed a dichotic listening selective attention task while ERPs were acquired...
April 19, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29679703/pc-pvt-2-0-an-updated-platform-for-psychomotor-vigilance-task-testing-analysis-prediction-and-visualization
#17
Jaques Reifman, Kamal Kumar, Maxim Y Khitrov, Jianbo Liu, Sridhar Ramakrishnan
BACKGROUND: The psychomotor vigilance task (PVT) has been widely used to assess the effects of sleep deprivation on human neurobehavioral performance. To facilitate research in this field, we previously developed the PC-PVT, a freely available software system analogous to the "gold-standard" PVT-192 that, in addition to allowing for simple visual reaction time (RT) tests, also allows for near real-time PVT analysis, predictions, and visualization in a personal computer (PC)...
April 18, 2018: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/29671707/prediction-of-cognitive-performance-and-subjective-sleepiness-using-a-model-of-arousal-dynamics
#18
Svetlana Postnova, Steven W Lockley, Peter A Robinson
A model of arousal dynamics is applied to predict objective performance and subjective sleepiness measures, including lapses and reaction time on a visual Performance Vigilance Test (vPVT), performance on a mathematical addition task (ADD), and the Karolinska Sleepiness Scale (KSS). The arousal dynamics model is comprised of a physiologically based flip-flop switch between the wake- and sleep-active neuronal populations and a dynamic circadian oscillator, thus allowing prediction of sleep propensity. Published group-level experimental constant routine (CR) and forced desynchrony (FD) data are used to calibrate the model to predict performance and sleepiness...
April 2018: Journal of Biological Rhythms
https://www.readbyqxmd.com/read/29661836/fear-memory-consolidation-in-sleep-requires-protein-kinase-a
#19
Jiyeon Cho, Krzysztof A Sypniewski, Shoko Arai, Kazuo Yamada, Sonoko Ogawa, Constantine Pavlides
It is well established that protein kinase A (PKA) is involved in hippocampal dependent memory consolidation. Sleep is also known to play an important role in this process. However, whether sleep-dependent memory consolidation involves PKA activation has not been clearly determined. Using behavioral observation, animals were categorized into sleep and awake groups. We show that intrahippocampal injections of the PKA inhibitor Rp-cAMPs in post-contextual fear conditioning sleep produced a suppression of long-term fear memory, while injections of Rp-cAMPs during an awake state, at a similar time point, had no effect...
May 2018: Learning & Memory
https://www.readbyqxmd.com/read/29656092/sleep-deprivation-impairs-cognitive-performance-in-zebrafish-a-matter-of-fact
#20
Jaquelinne Pinheiro-da-Silva, Steven Tran, Ana Carolina Luchiari
The zebrafish (Danio rerio) has become a valuable model organism for behavioral studies examining learning and memory. Its diurnal circadian rhythm and characterized sleep-like state make it comparable to mammals, features that have contributed to establishing this small vertebrate as a translational model for sleep research. Despite sleep being an evolutionarily conserved behavior, its mechanisms and functions are still debated. Sleep deprivation is commonly associated with decreased attention, reduced responsiveness to external stimuli, altered locomotor activity and impaired performance on cognitive tasks...
April 12, 2018: Behavioural Processes
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