Jelena Zivković, Kammala Ananth Kumar, Rapuru Rushendran, Kaliappan Ilango, Nouran M Fahmy, Heba A S El-Nashar, Mohamed El-Shazly, Shahira M Ezzat, Guiomar Melgar-Lalanne, Alejandra Romero-Montero, Sheila I Peña-Corona, Gerardo Leyva-Gomez, Javad Sharifi-Rad, Daniela Calina
This review aims to provide an in-depth analysis of the pharmacological properties of mangiferin, focusing primarily on its bioavailability and mechanisms of action, and its potential therapeutic applications, especially in the context of chronic diseases. We conducted a comprehensive examination of in vitro and in vivo studies, as well as clinical trials involving mangiferin or plant extracts containing mangiferin. The primary source of mangiferin is Mangifera indica, but it's also found in other plant species from the families Anacardiaceae, Gentianaceae, and Iridaceae...
September 1, 2023: Naunyn-Schmiedeberg's Archives of Pharmacology