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https://www.readbyqxmd.com/read/29803894/impact-of-selective-serotonin-reuptake-inhibitors-ssris-during-pregnancy-and-lactation-a-focus-on-short-and-long-term-vascular-effects
#1
REVIEW
S Zullino, T Simoncini
SSRIs are the first choice for the treatment of mood disorders during pregnancy and lactation. Despite the known side effects, the benefits/risks balance suggests their use. Hypertensive disorders of pregnancy (HDP) and Intrauterine growth restriction (IUGR) are the main vascular effects of these drugs, with mechanisms that involves endothelial dysfunction in feto-placental system. These data are supported by animal models, even if preliminary findings are not yet adequately supported by molecular and clinical data...
May 24, 2018: Vascular Pharmacology
https://www.readbyqxmd.com/read/29769471/-ministry-of-health-2015-penultimate-year-children-and-survey-and-research-project-promoting-the-parenting-support-actual-conditions-report-on-the-results-of-the-investigation-on-allergy-control-in-day-care-centers-admissions-children-of-allergic-diseases-situation
#2
Noriyuki Yanagida, Motohiro Ebisawa, Toshio Katsunuma, Jyoji Yoshizawa
BACKGROUND: There are no reports on the prevalence and social acceptance of food allergies (FAs) and FAinduced symptoms in nursery schools in Japan. PURPOSE: The purpose of this study is to clarify the current status of FA among children in nurseries. METHODS: Investigations were conducted in childcare facilities nationwide through survey request forms found on the Web page or sent via post. RESULT: We received responses from 15722 out of the 32210 institutions (48...
2018: Arerugī, [Allergy]
https://www.readbyqxmd.com/read/29722178/external-validation-of-the-rapid-assessment-prioritisation-and-referral-tool-for-multidisciplinary-teams-in-medical-assessment-and-planning-units
#3
Stacey Sharp, Michelle Palmer, Simone L Dullaway, Kristy Fortnum, Michelle-Renee Jane, Inger Kwiecien, Angela Vivanti, Steven M McPhail
OBJECTIVE: The Rapid Assessment Prioritisation and Referral Tool (RAPaRT) was developed for identifying appropriate referrals to allied members of the multidisciplinary team in hospital medical assessment and planning units (MAPUs). This study examined the performance of the RAPaRT for identifying appropriate referrals as well as predicting requirement for admission to hospital and length of stay. METHODS: A prospective cohort study was conducted. The RAPaRT, inclusive of seven mandatory items, was completed by nurses for 195 patients presenting to a hospital ED and assessed in a MAPU external to the instrument development site...
May 2, 2018: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/29673337/communities-in-charge-of-alcohol-cica-a-protocol-for-a-stepped-wedge-randomised-control-trial-of-an-alcohol-health-champions-programme
#4
Penny A Cook, Suzy C Hargreaves, Elizabeth J Burns, Frank de Vocht, Steve Parrott, Margaret Coffey, Suzanne Audrey, Cathy Ure, Paul Duffy, David Ottiwell, Kiran Kenth, Susan Hare, Kate Ardern
BACKGROUND: Communities In Charge of Alcohol (CICA) takes an Asset Based Community Development (ABCD) approach to reducing alcohol harm. Through a cascade training model, supported by a designated local co-ordinator, local volunteers are trained to become accredited 'Alcohol Health Champions' to provide brief opportunistic advice at an individual level and mobilise action on alcohol availability at a community level. The CICA programme is the first time that a devolved UK region has attempted to coordinate an approach to building health champion capacity, presenting an opportunity to investigate its implementation and impact at scale...
April 19, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29618962/development-of-hospital-based-data-sets-as-a-vehicle-for-implementation-of-a-national-electronic-health-record
#5
Leila Keikha, Seyede Sedigheh Seied Farajollah, Reza Safdari, Marjan Ghazisaeedi, Niloofar Mohammadzadeh
Background: In developing countries such as Iran, international standards offer good sources to survey and use for appropriate planning in the domain of electronic health records (EHRs). Therefore, in this study, HL7 and ASTM standards were considered as the main sources from which to extract EHR data. Objective: The objective of this study was to propose a hospital data set for a national EHR consisting of data classes and data elements by adjusting data sets extracted from the standards and paper-based records...
2018: Perspectives in Health Information Management
https://www.readbyqxmd.com/read/29596347/health-impacts-and-economic-costs-of-air-pollution-in-the-metropolitan-area-of-skopje
#6
Gerardo Sanchez Martinez, Joseph V Spadaro, Dimitris Chapizanis, Vladimir Kendrovski, Mihail Kochubovski, Pierpaolo Mudu
BACKGROUND: Urban outdoor air pollution, especially particulate matter, remains a major environmental health problem in Skopje, the capital of the former Yugoslav Republic of Macedonia. Despite the documented high levels of pollution in the city, the published evidence on its health impacts is as yet scarce. METHODS: we obtained, cleaned, and validated Particulate Matter (PM) concentration data from five air quality monitoring stations in the Skopje metropolitan area, applied relevant concentration-response functions, and evaluated health impacts against two theoretical policy scenarios...
March 29, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29458361/health-services-in-trinidad-throughput-throughput-challenges-and-the-impact-of-a-throughput-intervention-on-overcrowding-in-a-public-health-institution
#7
Mandreker Bahall
BACKGROUND: Throughput might be partially responsible for sub-optimum organisational and medical outcomes. The present study examined throughput and the challenges to ensuring optimum throughput in hospitals, and determined the effectiveness of a throughput intervention in reducing overcrowding in a public healthcare institution in Trinidad and Tobago. METHODS: First, a literature review of throughput and its processes in relation to improving hospital care was conducted...
February 20, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29420102/family-appraisal-of-paediatric-acquired-brain-injury-a-social-work-clinical-intervention-trial
#8
Lyndal Hickey, Vicki Anderson, Stephen Hearps, Brigid Jordan
OBJECTIVE: To compare the efficacy of a new intervention 'Family Forward' with 'Usual Care' social work practice in optimising family appraisal of a child's acquired brain injury to ensure better adaptation during the inpatient rehabilitation phase of care and early transition home. RESEARCH DESIGN: Single site, prospective, sequential comparison group design. METHODS AND PROCEDURES: Families were recruited on admission to an inpatient rehabilitation service based at a tertiary paediatric hospital...
February 8, 2018: Developmental Neurorehabilitation
https://www.readbyqxmd.com/read/29323989/rapid-response-a-multiprofessional-approach-to-hospital-at-home
#9
Sara Dowell, George Moss, Katy Odedra
The provision of 'hospital at home' is not new to the 21st century but pressure from the reduction in the number of hospital beds, population growth, an ageing population and subsequent extended time living with long-term conditions means such services are increasingly necessary. However, research by the authors found services that already exist do not operate 24 hours a day or provide a single multiprofessional approach. Gloucestershire's rapid response (RR) service provides specialist, coordinated, comprehensive and supportive assessment and treatment 24 hours a day in the patient's own home...
January 11, 2018: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/29310641/health-services-research-in-patients-with-breast-cancer-camiss-prospective-study-protocol-for-an-observational-prospective-study
#10
Susana García-Gutierrez, Miren Orive, Cristina Sarasqueta, Maria Jose Legarreta, Nerea Gonzalez, Maximino Redondo, Amado Rivero, Pedro Serrano-Aguilar, Xavier Castells, Jose Maria Quintana, Maria Sala
BACKGROUND: Though breast cancer remains a major health problem, there is a lack of information on health care provided to patients with this disease and associated costs. In addition, there is a need to update and validate risk stratification tools in Spain. Our purpose is to evaluate the health services provided for breast cancer in Spain, from screening and diagnosis to treatment and prognosis. METHODS: Prospective cohort study involving 13 hospitals in Spain with a follow-up period of up to 5 years after diagnostic biopsy...
January 8, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29229044/the-commercialization-of-patient-related-decision-making-in-hospitals
#11
Karl-Heinz Wehkamp, Heinz Naegler
BACKGROUND: Hospitals must make a profit to ensure their continued existence. The observed rises in case numbers and case-mix indices lead us to suspect that the admission, treatment, and discharge of patients are now being influenced not just by purely medical factors, but also by economic considerations with a view toward making a profit-i.e., that decision-making has become partially commercialized. In this study, we investigated whether doctors and hospital chief executive officers (CEOs) share this perception of their professional environment...
November 24, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29227898/responsiveness-of-the-personal-and-social-performance-scale-in-patients-with-schizophrenia
#12
En-Chi Chiu, Tsui-Mei Hung, Chiu-Min Huang, Shu-Chun Lee, Ching-Lin Hsieh
The responsiveness (ability to detect change) of the Personal and Social Performance scale (PSP) is largely unknown, limiting its use as an outcome measure. The purpose of this study was to examine both internal and external responsiveness of the PSP in patients with schizophrenia in the acute phase. Eighty patients were administered the PSP and the Clinical Global Impression-Severity scale (CGI-S) at admission and at discharge. We used the standardized effect size, the standardized response mean, and paired t-test for examining internal responsiveness...
November 27, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29223042/experiences-of-early-labour-management-from-perspectives-of-women-labour-companions-and-health-professionals-a-systematic-review-of-qualitative-evidence
#13
REVIEW
Sarah Beake Rm Ma Research Associate, Yan-Shing Chang Ba MPhil PhD Lecturer, Helen Cheyne Rm Rgn MSc PhD Professor Of Midwifery, Helen Spiby MPhil Rn Rm Professor Of Midwifery, Jane Sandall Rm MSc PhD Professor Of Social Science And Women's Health, Debra Bick
OBJECTIVES: to examine evidence of women's, labour companions' and health professionals' experiences of management of early labour to consider how this could be enhanced to better reflect women's needs. DESIGN: a systematic review of qualitative evidence. SETTING AND PARTICIPANTS: women in early labour with term, low risk singleton pregnancies, not booked for a planned caesarean birth or post-dates induction of labour, their labour companions, and health professionals responsible for early labour care (e...
February 2018: Midwifery
https://www.readbyqxmd.com/read/29184413/near-fatal-asthma-responsive-to-mepolizumab-after-failure-of-omalizumab-and-bronchial-thermoplasty
#14
Francesco Menzella, Carla Galeone, Mirco Lusuardi, Anna Simonazzi, Claudia Castagnetti, Patrizia Ruggiero, Nicola Facciolongo
Severe asthma affects between 5% and 10% of patients with asthma worldwide and requires best standard therapies at maximal doses, but there is a subgroup of patients refractory to all treatments. We share a case report of a 53-year-old woman with a history of severe allergic asthma that progressively worsened over the years despite the best therapy. She had been hospitalized 35 times, including nine admissions to the respiratory intensive care unit due to severe exacerbations. To rule out other possible diagnoses, several investigations were performed, such as computed tomography scan of the chest and neck, fiberoptic laryngoscopy, antineutrophil cytoplasmic antibodies, and complete blood cell count...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29182618/impact-of-scale-of-aggregation-on-associations-of-cardiovascular-hospitalization-and-socio-economic-disadvantage
#15
Ivan C Hanigan, Thomas Cochrane, Rachel Davey
BACKGROUND: There are numerous studies that show an increased incidence of cardiovascular disease with increasing levels of socio-economic disadvantage. Exposures that might influence the relationship include elements of the built environment and social systems that shape lifestyle risk behaviors. In Canberra (the Australian capital city) there has been a particular housing policy to create 'mixed-tenure' neighborhoods so that small pockets of disadvantage are surrounded by more affluent residences (known as a 'salt-and-pepper' pattern)...
2017: PloS One
https://www.readbyqxmd.com/read/29117024/behavioral-genetics-in-criminal-and-civil-courts
#16
Maya Sabatello, Paul S Appelbaum
Although emerging findings in psychiatric and behavioral genetics create hope for improved prevention, diagnosis, and treatment of disorders, the introduction of such data as evidence in criminal and civil proceedings raises a host of ethical, legal, and social issues. Should behavioral and psychiatric genetic data be admissible in judicial proceedings? If so, what are the various means for obtaining such evidence, and for what purposes should its admission be sought and permitted? How could-and should-such evidence affect judicial outcomes in criminal and civil proceedings? And what are the potential implications of using behavioral and psychiatric genetic evidence for individuals and communities, and for societal values of equality and justice? This article provides an overview of the historical and current developments in behavioral genetics...
November 2017: Harvard Review of Psychiatry
https://www.readbyqxmd.com/read/29102693/children-with-chronic-pain-response-trajectories-after-intensive-pain-rehabilitation-treatment
#17
Laura E Simons, Christine B Sieberg, Caitlin Conroy, Edin T Randall, Julie Shulman, David Borsook, Charles Berde, Navil F Sethna, Deirdre E Logan
Intensive pain rehabilitation programs for children with chronic pain are effective for many patients. However, characteristics associated with treatment response have not been well documented. In this article we report trajectories of pain and functional impairment in patients with chronic pain up to 1 year after intensive pain rehabilitation and examine baseline factors associated with treatment response. Patients (n = 253) with chronic pain and functional disability were assessed at 5 time points (admission, discharge, 1-month, 4-month, and 12-month follow-ups)...
February 2018: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29090032/the-psychological-abuse-of-the-elderly-a-silent-factor-of-cardiac-decompensation
#18
Adina Carmen Ilie, Anca Iuliana Pîslaru, Ioana Dana Alexa, Adriana Pancu, Ovidiu Gavrilovici, Aliona Dronic
Abuse of the elderly is a major issue debated worldwide. The most commonly identified form of abuse is the physical abuse. It is also the most frequently studied in the medical literature. However, at least six types of elder abuse are identified, and physical abuse is found in a small proportion of the cases. The consequences of abuse are frequent and, by prolonging hospitalizations, they will be associated with high costs of medical services, and patient's lack of self-confidence which, in time, may lead to social isolation, somatization, anxiety, depression, and suicide attempts...
June 2017: Mædica
https://www.readbyqxmd.com/read/29071577/obstetric-care-quality-indicators-and-outcomes-based-on-the-degree-of-acculturation-of-immigrants-results-from-a-cross-sectional-study-in-berlin
#19
Matthias David, Theda Borde, Silke Brenne, Babett Ramsauer, Larry Hinkson, Wolfgang Henrich, Oliver Razum, Jürgen Breckenkamp
HYPOTHESIS: Acculturation is a complex, multidimensional process involving the integration of the traditional norms, values, and lifestyles of a new cultural environment. It is, however, unclear what impact the degree of acculturation has on obstetric outcomes. METHODS: Data collection was performed in 2011 and 2012 at three obstetric tertiary centers in Berlin, Germany. Standardized interviews (20-30 min.) were performed with support of evaluated questionnaires...
February 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29061222/international-multicentre-randomised-controlled-trial-of-improvisational-music-therapy-for-children-with-autism-spectrum-disorder-time-a-study
#20
Mike J Crawford, Christian Gold, Helen Odell-Miller, Lavanya Thana, Sarah Faber, Jörg Assmus, Łucja Bieleninik, Monika Geretsegger, Claire Grant, Anna Maratos, Stephan Sandford, Amy Claringbold, Helen McConachie, Morag Maskey, Karin Antonia Mössler, Paul Ramchandani, Angela Hassiotis
BACKGROUND: Preliminary studies have indicated that music therapy may benefit children with autism spectrum disorders (ASD). OBJECTIVES: To examine the effects of improvisational music therapy (IMT) on social affect and responsiveness of children with ASD. DESIGN: International, multicentre, three-arm, single-masked randomised controlled trial, including a National Institute for Health Research (NIHR)-funded centre that recruited in London and the east of England...
October 2017: Health Technology Assessment: HTA
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