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General anxiety disorder

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https://www.readbyqxmd.com/read/29334641/do-clinically-anxious-children-cluster-according-to-their-expression-of-factors-that-maintain-child-anxiety
#1
Samantha Pearcey, Anna Alkozei, Bhismadev Chakrabarti, Helen Dodd, Kou Murayama, Suzannah Stuijfzand, Cathy Creswell
BACKGROUND: Cognitive Behaviour Therapy (CBT) is an effective treatment for childhood anxiety disorders, yet a significant proportion of children do not benefit from it. CBT for child anxiety disorders typically includes a range of strategies that may not all be applicable for all affected children. This study explored whether there are distinct subgroups of children with anxiety disorders who are characterized by their responses to measures of the key mechanisms that are targeted in CBT (i...
January 3, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29333493/a-quality-improvement-project-aimed-at-adapting-primary-care-to-ensure-the-delivery-of-evidence-based-psychotherapy-for-adult-anxiety
#2
Mark D Williams, Craig N Sawchuk, Nathan D Shippee, Kristin J Somers, Summer L Berg, Jay D Mitchell, Angela B Mattson, David J Katzelnick
Primary care patients frequently present with anxiety with prevalence ratios up to 30%. Brief cognitive-behavioural therapy (CBT) has been shown in meta-analytic studies to have a strong effect size in the treatment of anxiety. However, in surveys of anxious primary care patients, nearly 80% indicated that they had not received CBT. In 2010, a model of CBT (Coordinated Anxiety Learning and Management (CALM)) adapted to primary care for adult anxiety was published based on results of a randomised controlled trial...
2018: BMJ Open Quality
https://www.readbyqxmd.com/read/29332635/fear-of-hypoglycemia-in-patients-with-type-2-diabetes-the-role-of-interoceptive-accuracy-and-prior-episodes-of-hypoglycemia
#3
Jennifer Grammes, Manuela Schäfer, Andrea Benecke, Ulrike Löw, Alena-Lynn Klostermann, Thomas Kubiak, Michael Witthöft
OBJECTIVE: Fear of hypoglycemia (FoH) is a limiting factor for diabetes self-management and can have detrimental effects on quality of life. However, relatively little is known about its underlying mechanisms. In line with findings on patients with anxiety disorders, we hypothesized that interoceptive accuracy (IA) might be positively linked to FoH in patients with type 2 diabetes (T2DM). METHODS: 133 patients with T2DM were screened according to the extreme quartiles of the Hypoglycemia Fear Survey worry subscale (HFS-W)...
February 2018: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29332099/association-between-the-intron-8-vntr-polymorphism-of-the-dat1-gene-and-crack-cocaine-addiction
#4
Anderson R Stolf, Diana Müller, Jaqueline B Schuch, Gláucia C Akutagava-Martins, Luciano S P Guimaraes, Claudia M Szobot, Ricardo Halpern, Felix H P Kessler, Flavio Pechansky, Tatiana Roman
BACKGROUND: This study aims to compare allele and genotype frequencies of a 30-bp variable number of tandem repeats (VNTR) polymorphism of the DAT1 gene, located at intron 8, between adult crack cocaine users and nonaddicted individuals. Due to its involvement in drug addiction, this gene is a good candidate for molecular studies. METHODS: A cross-sectional sample of 239 current adult crack abusers or dependents from in- and outpatient clinics and 211 control individuals was collected in Brazil...
January 12, 2018: Neuropsychobiology
https://www.readbyqxmd.com/read/29331354/specificity-in-etiology-of-subtypes-of-bipolar-disorder-evidence-from-a-swedish-population-based-family-study
#5
Jie Song, Ralf Kuja-Halkola, Arvid Sjölander, Sarah E Bergen, Henrik Larsson, Mikael Landén, Paul Lichtenstein
BACKGROUND: Uncertainty remains whether bipolar I disorder (BDI) and bipolar II disorder (BDII) differ etiologically. We used a population-based family sample to examine the etiological boundaries between BDI and BDII by assessing their familial aggregation/coaggregation and by assessing the coaggregation between them and schizophrenia, depression, attention-deficit/hyperactivity disorder, eating disorders, autism spectrum disorder, substance use disorders, anxiety disorders, and personality disorders...
November 20, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/29330031/mental-health-disorders-mediate-association-of-sexual-minority-identity-with-cardiovascular-disease
#6
Lezhou Wu, Randy L Sell, Alexis M Roth, Seth L Welles
BACKGROUND: Little is known about cardiovascular health disparities for lesbian, gay, or bisexual (LGB) persons and whether these disparities are mediated by mental health disorders due to sexual minority stress. We hypothesize LGB identity is associated with an increased risk of cardiovascular disease (CVD) and that major depressive disorder (MDD) and generalized anxiety disorders (GAD) may mediate this association. METHODS: The National Epidemiologic Survey on Alcohol and Related Conditions is a longitudinal, nationally-representative study of non-institutionalized U...
January 9, 2018: Preventive Medicine
https://www.readbyqxmd.com/read/29329979/how-acute-stress-may-enhance-subsequent-memory-for-threat-stimuli-outside-the-focus-of-attention-dlpfc-amygdala-decoupling
#7
Yu Luo, Guillén Fernández, Erno Hermans, Susanne Vogel, Yu Zhang, Hong Li, Floris Klumpers
Stress-related disorders, e.g., anxiety and depression, are characterized by decreased top-down control for distracting information, as well as a memory bias for threatening information. However, it is unclear how acute stress biases mnemonic encoding and leads to prioritized storage of threat-related information even if outside the focus of attention. In the current study, healthy adults (N = 53, all male) were randomly assigned to stress induction using the socially evaluated cold-pressor test (SECPT) or a control condition...
January 9, 2018: NeuroImage
https://www.readbyqxmd.com/read/29327316/-diagnosis-differential-diagnosis-and-therapy-of-substance-use-disorders-in-general-hospital-general-section
#8
REVIEW
Anton Schmick, Josef Jenewein, Sönke Böttger
Substance use disorders are becoming an increasingly significant problem in general hospitals and hence play a key role in consultation- and liaison psychiatry. Diverse psychotropic effects of various substances mimic psychiatric disorders. An alcohol intoxication can present depressive or manic symptoms, a cannabis delirium can present as a psychosis while stimulants use can suggest the diagnosis of an anxiety disorder. Obtaining dual diagnoses by identifying substance-induced and non-substance-induced psychopathologies is clinically challenging...
January 11, 2018: Neuropsychiatrie: Klinik, Diagnostik, Therapie und Rehabilitation
https://www.readbyqxmd.com/read/29325731/pharmacogenomic-testing-in-child-and-adolescent-psychiatry-an-evidence-based-review
#9
Anna M Wehry, Laura Ramsey, Shane E Dulemba, Sarah A Mossman, Jeffrey R Strawn
Significant advances have been made in the application of pharmacogenomic testing for the treatment of patients with psychiatric disorders. Over the past decade, a number of studies have evaluated the utility of pharmacogenomic testing in pediatric patients with psychiatric disorders. The evidence base for pharmacogenomic testing in youth with depressive and anxiety disorders as well as attention/deficit hyperactivity disorder (ADHD) is reviewed in this article. General pharmacogenomic principles are summarized and functional polymorphisms in P450 enzymes (and associated metabolizer phenotypes), the serotonin transporter promoter polymorphisms, serotonin 2 A receptor genes (e...
January 8, 2018: Current Problems in Pediatric and Adolescent Health Care
https://www.readbyqxmd.com/read/29323198/paroxysmal-nocturnal-hemoglobinuria-pnh-brain-mri-ischemic-lesions-in-neurologically-asymtomatic-patients
#10
Wilma Barcellini, Elisa Scola, Silvia Lanfranconi, Marika Grottaroli, Francesca Binda, Bruno Fattizzo, Anna Zaninoni, Gloria Valcamonica, Claudia Maria Cinnante, Carla Boschetti, Massimiliano Buoli, Carlo Alfredo Altamura, Nereo Bresolin, Fabio Triulzi, Alberto Zanella, Agostino Cortelezzi
This study investigated for the first time brain ischemic involvement in 19 consecutive neurologically asymptomatic PNH patients by non-enhanced cerebral MRI, and by intracranial arterial and venous angio-MRI. Eleven cases (58%, 7 aged <65) showed pathological findings: 9 white matter (WM) abnormalities related to chronic ischemic small vessel disease, 2 a focal abnormality >5 mm, and 5 cases a score >4 by the age-related white matter changes (ARWMC) scale. Compared with age and sex-matched controls (1:2 ratio), patients showed an increased frequency of periventricular WM vascular degeneration (32% versus 5...
January 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29321671/preconception-carrier-screening-for-multiple-disorders-evaluation-of-a-screening-offer-in-a-dutch-founder-population
#11
Inge B Mathijssen, Kim C A Holtkamp, Cecile P E Ottenheim, Janneke M C van Eeten-Nijman, Phillis Lakeman, Hanne Meijers-Heijboer, Merel C van Maarle, Lidewij Henneman
Technological developments have enabled carrier screening for multiple disorders. This study evaluated experiences with a preconception carrier screening offer for four recessive disorders in a Dutch founder population. Questionnaires were completed by 182 attendees pretesting and posttesting and by 137 non-attendees. Semistructured interviews were conducted with seven of the eight carrier couples. Attendees were mainly informed about the existence of screening by friends/colleagues (49%) and family members (44%)...
January 10, 2018: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/29313758/introduction-to-the-special-section-integrative-approaches-for-treating-violent-loss-survivors
#12
Joah L Williams, Alyssa A Rheingold
Survivors of sudden, traumatic death are at risk for a variety of bereavement-related mental health problems, including posttraumatic stress disorder, depression, and prolonged grief disorder. Because these conditions often cooccur, traumatic grief interventions are generally designed to be transdiagnostic, integrative treatments that combine techniques designed to treat a wide range of mood and anxiety symptoms. In this special section, expert clinicians and researchers present a series of papers describing new, integrative treatment models for violently bereaved children and adults and also describe ways that integrative treatments can be enhanced using peer support...
January 9, 2018: Death Studies
https://www.readbyqxmd.com/read/29310620/does-presence-of-metabolic-syndrome-impact-anxiety-and-depressive-disorder-screening-results-in-middle-aged-and-elderly-individuals-a-population-based-study
#13
Jurate Butnoriene, Vesta Steibliene, Ausra Saudargiene, Adomas Bunevicius
BACKGROUND: Depressive and anxiety disorders are common in primary care setting but often remain undiagnosed. Metabolic syndrome (MetS) is also prevalent in the general population and can impair recognition of common mental disorders due to significant co-morbidity and overlap with psychiatric symptoms included in self-reported depression/anxiety screening tools. We investigated if MetS has an impact on the accuracy of current major depressive disorder (MDD) and generalized anxiety disorder (GAD) screening results using the Hospital Anxiety and Depression scale (HADS)...
January 8, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29310485/enhanced-innate-fear-and-altered-stress-axis-regulation-in-vglut3-knockout-mice
#14
Diána Balázsfi, Anna Fodor, Bibiána Török, Szilamér Ferenczi, Krisztina J Kovács, József Haller, Dóra Zelena
Glutamatergic neurons, characterized by vesicular glutamate transporters (VGluT1-3) provide the main excitation in the brain. Their disturbances have been linked to various brain disorders, which could be also modeled by the contextual fear test in rodents. We aimed to characterize the participation of VGluT3 in the development of contextual fear through its contribution to hypothalamic-pituitary-adrenocortical axis (HPA) regulation using knockout (KO) mice. Contextual fear conditioning was induced by foot shock and mice were examined 1 and 7 d later in the same environment comparing wild type with KO...
January 8, 2018: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29310453/the-relationship-between-sleep-quality-and-fibromyalgia-symptoms
#15
Alexandro Andrade, Guilherme Torres Vilarino, Sofia Mendes Sieczkowska, Danilo Reis Coimbra, Guilherme Guimarães Bevilacqua, Ricardo de Azevedo Klumb Steffens
This study investigated the relationship between sleep quality and fibromyalgia symptoms in 326 patients. The Pittsburgh Sleep Quality Index was used to assess the presence of sleep disorders. Multivariate analysis of variance was performed to determine the influence of fibromyalgia symptoms on sleep quality. The prevalence of sleep disorders was 92.9 percent. Patients reported generalized pain (88.3%), memory failure (78.5%), moodiness (59%), excessive anxiety (77.5%), and concentration difficulties (69...
January 1, 2018: Journal of Health Psychology
https://www.readbyqxmd.com/read/29309956/public-stigma-of-prolonged-grief-disorder-an-experimental-study
#16
Maarten C Eisma
Prolonged grief disorder (PGD), characterized by severe, persistent and disabling grief, is being considered for inclusion in the International Classification of Diseases' 11 (ICD-11) and a related disorder, Persistent Complex Bereavement Disorder (PCBD), is included for further investigation in the Diagnostic and Statistical Manual of Mental Disorders 5 (DSM-5). Establishing diagnoses for pathological grief may lead to stigmatization. Additionally, it has been argued that people experiencing severe grief responses after loss of non-family members (i...
January 2, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29307325/anxiety-and-depression-in-adult-first-seizure-presentations
#17
Ciaran Lane, Candice Crocker, Karen Legg, Mallory Borden, Bernd Pohlmann-Eden
OBJECTIVE: To define the prevalence of psychiatric symptoms of anxiety and depression in patients at the time of their first seizure presentation to a neurologist. METHODS: Our pilot study uses a cohort approach with multimodal data (clinical, social, structural [3T magnetic resonance imaging], and functional [electroencephalogram]). We screened 105 patients referred to the Halifax First Seizure Clinic between 2014 and 2016 and 51 controls. All participants completed two screening questionnaires: Neurological Disorders Depression Inventory for Epilepsy and Generalized Anxiety Disorder 7-Item...
January 8, 2018: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29306905/-the-importance-of-anxiety-and-depression-in-family-practice
#18
Peter Torzsa, Csenge Hargittay, Laszlo Kalabay
Representative studies indicate that prevalence of anxiety disorders among adults is between 12.6-17.2%, while in Hungary it is 17.7%. According to both international and national studies the point prevalence of diagnosed major depression requiring treatment is 6-10 % in general practice. As untreated depression is the most important risk factor for suicide, early detection and effective management of depression are critical in prevention. According to international and national studies the recognition of major depression in primary care significantly contributes to the decline of suicide mortality...
September 2017: Neuropsychopharmacologia Hungarica
https://www.readbyqxmd.com/read/29306870/gender-differences-in-the-well-being-of-patients-diagnosed-with-chlamydia-trachomatis-a-cross-sectional-study
#19
Nirina Andersson, Helena Carré, Urban Janlert, Jens Boman, Elisabet Nylander
OBJECTIVES: We aimed to investigate how an infection with Chlamydia trachomatis (CT) influenced patients' well-being and whether there were differences due to gender, age or relationship status, in an effort to strengthen preventive measures and provide better healthcare for patients with CT. METHODS: Patients diagnosed with CT in the county of Västerbotten, Sweden, were asked to fill out a questionnaire about their feelings, thoughts and actions after CT diagnosis...
January 6, 2018: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/29306117/difficulties-in-emotion-regulation-in-treatment-seeking-alcoholics-with-and-without-co-occurring-mood-and-anxiety-disorders
#20
Clara M Bradizza, Whitney C Brown, Melanie U Ruszczyk, Kurt H Dermen, Joseph F Lucke, Paul R Stasiewicz
Emotion regulation difficulties (ERD) are known to underlie mental health conditions including anxiety and depressive disorders and alcohol use disorder (AUD). Although AUD, mood, and anxiety disorders commonly co-occur, no study has examined the association between these disorders and ERD among AUD outpatients. In the current study, emotion regulation (ER) scores of AUD individuals with no co-occurring mental health condition were compared to the ER scores of individuals who met diagnostic criteria for co-occurring mood and/or anxiety disorders...
December 29, 2017: Addictive Behaviors
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