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General anxiety disorder

R Parisi, R T Webb, C E Kleyn, M J Carr, N Kapur, C E M Griffiths, D M Ashcroft
BACKGROUND: Psychological distress among people with psoriasis may lead to elevated risks of suicide and non-fatal self-harm. OBJECTIVES: To investigate psychiatric comorbidity, psychotropic medication prescribing and risk of suicidality in people with psoriasis. METHODS: A cohort of patients with psoriasis (1998-2014) was delineated using the Clinical Practice Research Datalink, with linkage to Hospital Episode Statistics and Office for National Statistics mortality records...
July 14, 2018: British Journal of Dermatology
Jake Linardon, Ellen E Fitzsimmons-Craft, Leah Brennan, Mary Barillaro, Denise E Wilfley
OBJECTIVE: Dropout is one factor that might limit the effectiveness of interpersonal psychotherapy (IPT). Improved understanding of IPT dropout is an important research priority. This meta-analysis examined dropout rates from IPT in randomized controlled trials. METHOD: Seventy-two trials met inclusion criteria. RESULTS: The weighted mean dropout rate from IPT was 20.6% (95% CI = 17.4-24.2). Dropout rates were similar for depressive (20...
July 13, 2018: Psychotherapy Research: Journal of the Society for Psychotherapy Research
Theresa Katharina Haidl, Marlene Rosen, Stephan Ruhrmann, Joachim Klosterkötter
In recent years an increased comorbidity of schizophrenic disorders with anxiety disorders has been reported. Thus, among patients with a disorder from the schizophrenia spectrum, a general anxiety disorder was found in 38.3 % of patients, with 14.9 % of these with social phobia (SP). Especially social anxiety (SA) is of particular importance because it is often associated with depression and can contribute to psychosocial disabilities in patients with psychosis.Anxiety disorders already seem to occur prior to the first psychotic manifestation in the clinical high-risk state (CHR)...
July 13, 2018: Fortschritte der Neurologie-Psychiatrie
Samuel E Cooper, Christian Grillon, Shmuel Lissek
BACKGROUND: Fear conditioning is implicated as a central psychopathological mechanism of anxiety disorders. People with anxiety disorders typically demonstrate reduced affective discrimination between conditioned danger and safety cues. Here, affective discrimination refers to the ability to selectively display fear to dangerous but not safe situations. Though both generalized anxiety disorder (GAD) and panic disorder (PD) are linked to impaired affective discrimination, the clinical phenomenology of these disorders suggests that people with GAD versus PD might be less able to overcome such deficits...
July 4, 2018: Comprehensive Psychiatry
Evyn M Peters, Rudy Bowen, Lloyd Balbuena
OBJECTIVES: The purpose of this study was to determine whether mood instability in people with anxiety disorders contributes to trait impulsivity, non-suicidal self-injury, and binge eating/purging. METHODS: Data were analysed from a general population sample of 7,221 adults (Mage  = 51.0 years; 56.9% female). Logistic regression analyses with effect decompositions were used to establish the associations of five anxiety disorders (generalized anxiety disorder, social phobia, panic disorder, agoraphobia, and obsessive-compulsive disorder) with impulsivity, non-suicidal self-injury, and binge eating/purging, and then to determine the extent that adding mood instability to each model reduced these relationships...
July 12, 2018: Psychology and Psychotherapy
Erin C Berenz, Timothy P York, Hanaan Bing-Canar, Ananda B Amstadter, Briana Mezuk, Charles O Gardner, Roxann Roberson-Nay
PURPOSE: Posttraumatic stress disorder (PTSD) often co-occurs with panic disorder (PD), with some etiological models positing a causal role of panic reactivity in PTSD onset; however, data addressing the temporal ordering of these conditions are lacking. The aim of this study was to examine the bi-directional associations between PD and PTSD in a nationally representative, epidemiologic sample of trauma-exposed adults. METHODS: Participants were community-dwelling adults (62...
July 12, 2018: Social Psychiatry and Psychiatric Epidemiology
Sherifa Ahmed Hamed
OBJECTIVES: Pregabalin (PGB) is a gabapentinoid (ie, GABA analog), which has been Food and Drug Administration-approved for treatment of partial epilepsy in adults and neuropathic pain. It also has off-label uses for the treatment of generalized anxiety disorders, fibromyalgia, and tension headache and prevention of migraine. Few cases were reported with sexual dysfunctions (SDs) as adverse effects of PGB and gabapentin, and the majority were dose related (≥900 mg/d for gabapentin)...
July 2018: Clinical Neuropharmacology
Sarah Turner, Natalie Mota, James Bolton, Jitender Sareen
BACKGROUND: The comorbidity of mood and anxiety disorders (MD and AD) with substance use disorders (SUD) is common. One explanation for this comorbidity is the self-medication hypothesis, which posits that individuals with MD or AD use substances to cope with the difficult symptoms associated with the disorder. Over time, self-medication (SM) can develop into an independent SUD. This narrative review will present the prevalence and correlates of SM with alcohol and/or drugs for MD and AD and the relationship between SM and subsequent SUD using both cross-sectional and longitudinal epidemiological data...
July 12, 2018: Depression and Anxiety
Marie-Michèle Tanguay Bernard, Mireille Luc, Jean-Daniel Carrier, Louise Fournier, Arnaud Duhoux, Elodie Côté, Olivier Lessard, Catherine Gibeault, Christian Bocti, Pasquale Roberge
Background: Benzodiazepines are among the most commonly prescribed drugs for anxiety disorders. While they are indicated as adjunctive treatment for short-term use according to clinical practice guidelines, previous studies have shown patterns of long-term use of benzodiazepines, which is problematic due to side effects, dependence and potential of abuse. The aims of this study were to examine among a large sample of primary care adults suffering from anxiety disorders: 1) benzodiazepine use patterns; and 2) correlates of long-term benzodiazepine use...
July 2018: Heliyon
Hoda Doos Ali Vand, Banafsheh Gharraee, Ali-Asghar Asgharnejad Farid, Mir Farhad Ghaleh Bandi, Mojtaba Habibi
Objective: Similar cognitive and behavioral factors underlie and perpetuate insomnia and emotional disorders. This brief case report aims to evaluate the effectiveness of the Unified Protocol (UP), a transdiagnostic treatment designed to target emotional disorders in treating comorbid insomnia. Method : The patient was a 32-year-old male, who met the DSM-IV-TR criteria for chronic insomnia, major depressive disorder, and generalized anxiety disorder. After 3 baseline weeks, the patient underwent 14 sessions of UP and was retested after 1-month follow-up...
April 2018: Iranian Journal of Psychiatry
Rolands Ivanovs, Anda Kivite, Douglas Ziedonis, Iveta Mintale, Jelena Vrublevska, Elmars Rancans
Background: Depression and anxiety have been recognized as independent risk factors for both the development and prognosis of cardiovascular (CV) diseases (CVD). The Systematic Coronary Risk Evaluation (SCORE) function measures the 10-year risk of a fatal CVD and is a crucial tool for guiding CV patient management. This study is the first in Latvia to investigate the association of depression and anxiety with the 10-year CV mortality risk in a primary care population. Methods: This cross-sectional study was conducted at 24 primary care facilities...
2018: Frontiers in Psychiatry
Hale Yapici Eser, Anil S Kacar, Can M Kilciksiz, Merve Yalçinay-Inan, Dost Ongur
Objective: Bipolar disorder is highly comorbid with anxiety disorders, however current and lifetime comorbidity patterns of each anxiety disorder and their associated features are not well studied. Here, we aimed to conduct a meta-analysis and meta-regression study of current evidence. Method: We searched PubMed to access relevant articles published until September 2015, using the keywords "Bipolar disorder" or "Affective Psychosis" or "manic depressive" separately with "generalized anxiety," "panic disorder," "social phobia," "obsessive compulsive," and "anxiety...
2018: Frontiers in Psychiatry
L J Zhang, D F He, Y Yang, L H Pu, L Y Xu, Y X Zhou, M Y Liu
Objectives: Exploring the association between depression/anxiety and mental stress-induced myocardial ischemia (MSIMI) in patients with stable coronary artery disease (CAD). Methods: A total of 178 subjects was enrolled according to the inclusion and exclusion criterion with 88 men and 90 women at age of (54±12)years. The subjects were divided into four groups including CAD with depression/anxiety, CAD without depression/anxiety, depression/anxiety without CAD, and control group based on the state of coronary artery, the scores of Patient Health Questionnaire 9-item (PHQ-9) and Generalized Anxiety Disorder 7-item (GAD-7) ...
July 1, 2018: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
E Dauden, A J Blasco, C Bonanad, R Botella, J M Carrascosa, E González-Parra, E Jodar, B Joven, P Lázaro, A Olveira, J Quintero, R Rivera
BACKGROUND: The association between psoriasis and some diseases has become relevant in recent years. Providing appropriate management of psoriasis from an early stage requires prompt diagnosis and treatment of concomitant diseases and to prevent any potential comorbidity. This approach should consider the adverse events of the drugs used to treat psoriasis potentially related to the onset of comorbidities. OBJECTIVE: To provide the dermatologist with an accurate and friendly tool for systematising the diagnosis of psoriasis-associated comorbidities, which generally escapes the scope of the dermatology setting, and to facilitate decision-making about the referral and treatment of patients with comorbidities...
July 10, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
Carlijn Wiersema, Willeke Van Zelst, Richard Oude Voshaar
A 67-year-old man was referred to an outpatient clinic of geriatric psychiatry because of persistent symptoms of depression and anxiety, accompanied by sleepiness. The latter had been evaluated multiple times in the general practice over several years; each time it was considered to be a symptom of depression. After referral, the patient was diagnosed with severe obstructive sleep apnoea (OSA), comorbid to a depressive and anxiety disorder. Retrospectively, we conclude that affective symptoms accompanying OSA and sleepiness were wrongfully interpreted as depression, but after having led to problems at work, they have triggered psychiatric comorbidity...
July 10, 2018: BMJ Case Reports
Anke M Klein, Rian Bakens, Rianne E van Niekerk, Machteld A Ouwens, Ronald M Rapee, Susan M Bögels, Eni S Becker, Mike Rinck
BACKGROUND AND OBJECTIVES: Cognitive theories of fear suggest that biases in interpretation are content-specific: Fearful children should only interpret materials negatively if they are specifically related to the content of their fear. So far, there are only a few studies available that report on this postulated content-specificity of interpretation processes in childhood fear. The goal of this study was to examine interpretation bias and its content-specificity in children with varying levels of Generalized Anxiety Disorder (GAD) symptoms...
June 30, 2018: Journal of Behavior Therapy and Experimental Psychiatry
Sudha Kallakuri, Siddhardha Devarapalli, Anadya Prakash Tripathi, Anushka Patel, Pallab K Maulik
Background: About 10% Indians suffer from stress, depression or substance use disorders. Few receive care for these problems, especially in rural areas. Aims: As part of a broader initiative to deliver technology-enabled mental health services for rural communities (adults ≥18 years), information was collected about the prevalence of depression, anxiety and suicide risk. Method: The study was conducted in 12 villages in the West Godavari district of Andhra Pradesh...
July 2018: BJPsych Open
Silke Bachmann
Suicide is a worldwide phenomenon. This review is based on a literature search of the World Health Organization (WHO) databases and PubMed. According to the WHO, in 2015, about 800,000 suicides were documented worldwide, and globally 78% of all completed suicides occur in low- and middle-income countries. Overall, suicides account for 1.4% of premature deaths worldwide. Differences arise between regions and countries with respect to the age, gender, and socioeconomic status of the individual and the respective country, method of suicide, and access to health care...
July 6, 2018: International Journal of Environmental Research and Public Health
Adriana Bezerra de Carvalho, Taiane de Azevedo Cardoso, Thaíse Campos Mondin, Ricardo Azevedo da Silva, Luciano Dias de Mattos Souza, Pedro Vieira da Silva Magalhães, Karen Jansen
Premenstrual Dysphoric Disorder (PMDD) was recently included in DSM-5 as a full diagnostic category. Few studies have investigated PMDD in a community sample of young adults, especially in Brazil. Thus, the objective of this study was to evaluate the prevalence and the factors associated with PMDD in a community sample of 727 young adult women between the 18 and 24 years of age in southern Brazil. This was a cross-sectional population-based study. The data were collected from 2012 to 2014. PMDD was assessed using the Mini International Neuropsychiatry Interview (M...
June 26, 2018: Psychiatry Research
Anna M Baker, Janet T Holbrook, Abebaw M Yohannes, Michelle N Eakin, Elizabeth A Sugar, Robert J Henderson, Anne S Casper, David A Kaminsky, Alexis L Rea, Anne M Mathews, Loretta G Que, Joe W Ramsdell, Lynn B Gerald, Robert A Wise, Nicola A Hanania
RATIONALE: Anxiety is a common co-morbidity of Chronic Obstructive Pulmonary Disease (COPD) that is associated with higher morbidity and mortality. We evaluated three anxiety screening questionnaires, the Generalized Anxiety Disorder (GAD-7) questionnaire, the Hospital Anxiety and Depression Scale (HADS-A), and the Anxiety Inventory for Respiratory Disease (AIR). OBJECTIVES: Evaluate and compare thet test performance characteristics of 3 anxiety screening questionnaires using the Mini International Neuropsychiatric Interview (MINI) version 7...
July 9, 2018: Annals of the American Thoracic Society
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