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https://www.readbyqxmd.com/read/28538748/quality-of-life-considerations-and-pain-management-in-hidradenitis-suppurativa
#1
Gregor Be Jemec
All skin diseases involve some element of stigmatization and psychosocial consequence for the individual patient, but few, if any, skin diseases can match the impact of hidradenitis suppurativa (HS) on the patient. The inflamed lesions progressing to noninflamed nodules and abscesses are not only perceived as unclean and stigmatizing by the patients, but also cause pain and scarring making this inflammatory skin disorder unique. It is obvious that the disease has a significant negative impact on the patients' quality of life (QOL)...
June 2017: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28538024/effects-of-vilazodone-on-suicidal-ideation-and-behavior-in-adults-with-major-depressive-disorder-or-generalized-anxiety-disorder-post-hoc-analysis-of-randomized-double-blind-placebo-controlled-trials
#2
Michael E Thase, John Edwards, Suresh Durgam, Changzheng Chen, Cheng-Tao Chang, Maju Mathews, Carl P Gommoll
Treatment-emergent suicidal ideation and behavior are ongoing concerns with antidepressants. Vilazodone, currently approved for the treatment of major depressive disorder (MDD) in adults, has also been evaluated in generalized anxiety disorder (GAD). Post-hoc analyses of vilazodone trials were carried out to examine its effects on suicidal ideation and behavior in adults with MDD or GAD. Data were pooled from vilazodone trials in MDD (four studies) and GAD (three studies). The incidence of suicide-related events was analyzed on the basis of treatment-emergent adverse event reporting and Columbia-Suicide Severity Rating Scale (C-SSRS) monitoring...
May 19, 2017: International Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28533685/factor-structure-reliability-and-validity-of-the-japanese-version-of-the-hoarding-rating-scale-self-report-hrs-sr-j
#3
Aki Tsuchiyagaito, Satoshi Horiuchi, Toko Igarashi, Yoshiya Kawanori, Yoshiyuki Hirano, Hirooki Yabe, Akiko Nakagawa
BACKGROUND: The Hoarding Rating Scale-Self-Report (HRS-SR) is a five-item scale that assesses the symptoms of hoarding. These symptoms include excessive acquisition, difficulty in discarding, and excessive clutter that causes distress. We conducted three studies to examine the factor structure, reliability, and validity of the Japanese version of the HRS-SR (HRS-SR-J). METHODS: Study 1 examined its reliability; 193 college students and 320 adolescents and adults completed the HRS-SR-J and, of the college students, 32 took it again 2 weeks later...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28533148/repetitive-transcranial-magnetic-stimulation-of-the-right-dorsal-lateral-prefrontal-cortex-in-the-treatment-of-generalized-anxiety-disorder-a-randomized-double-blind-sham-controlled-clinical-trial
#4
Dancho Dilkov, Emily R Hawken, Emil Kaludiev, Roumen Milev
BACKGROUND: Up to 50% of people with GAD fail to respond to first-line pharmacotherapies for generalized anxiety disorder (GAD), partly due to poor treatment compliance rates and partly due to the complex physiology underlying GAD. Thus, new non-invasive techniques, like repetitive transcranial magnetic stimulation (rTMS) are being investigated. METHODS: Participants were recruited from two different mood disorder sites: Kingston, Ontario, Canada and Sofia, Bulgaria...
May 19, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28532510/gender-differences-in-psychiatric-diagnoses-in-older-people-with-intellectual-disability-a-register-study
#5
Anna Axmon, Magnus Sandberg, Gerd Ahlström
BACKGROUND: Gender differences regarding psychiatric ill-health are well known in the general population. However, not much research is done on people with intellectual disability, and especially not among older people with intellectual disability. METHODS: People with intellectual disability aged 55+ years in 2012 in Sweden were identified through a register containing information on those receiving support and service for this type of disability. The cohort comprised 3609 women and 4327 men with mean age 65 and 64 years, respectively...
May 22, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28530171/the-implications-of-psychological-symptoms-for-length-of-sick-leave
#6
Antonius Schneider, Sven Hilbert, Johannes Hamann, Svenja Skadsem, Jürgen Glaser, Bernd Löwe, Markus Bühner
BACKGROUND: In this cross-sectional study, we aimed to determine the relation between sick leave duration, burnout symptoms, depression, anxiety, and somatization in a primary care setting. METHODS: Patients receiving a sickness certificate in one of 14 participating primary care practices were consecutively asked by their primary care physician to fill in a questionnaire comprising the Maslach Burnout Inventory-General Survey (MBI-GS) and the Patient Health Questionnaire (PHQ) containing the depression (PHQ-9), somatization (PHQ-15), and anxiety (GAD-7) scales...
April 28, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/28529479/in-patients-undergoing-cochlear-implantation-psychological-burden-affects-tinnitus-and-the-overall-outcome-of-auditory-rehabilitation
#7
Petra Brüggemann, Agnieszka J Szczepek, Katharina Klee, Stefan Gräbel, Birgit Mazurek, Heidi Olze
Cochlear implantation (CI) is increasingly being used in the auditory rehabilitation of deaf patients. Here, we investigated whether the auditory rehabilitation can be influenced by the psychological burden caused by mental conditions. Our sample included 47 patients who underwent implantation. All patients were monitored before and 6 months after CI. Auditory performance was assessed using the Oldenburg Inventory (OI) and Freiburg monosyllable (FB MS) speech discrimination test. The health-related quality of life was measured with Nijmegen Cochlear implantation Questionnaire (NCIQ) whereas tinnitus-related distress was measured with the German version of Tinnitus Questionnaire (TQ)...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28529365/long-noncoding-rnas-new-evidence-for-overlapped-pathogenesis-between-major-depressive-disorder-and-generalized-anxiety-disorder
#8
Xuelian Cui, Wei Niu, Lingming Kong, Mingjun He, Kunhong Jiang, Shengdong Chen, Aifang Zhong, Wanshuai Li, Jim Lu, Liyi Zhang
BACKGROUND: About half of patients with major depressive disorder (MDD) have clinically meaningful levels of anxiety. Greater severity of depressive illness and functional impairment has been reported in patients with high levels of anxiety accompanying depression. The pathogenesis for the comorbidity was still unsure. AIM: This study aimed to determine whether there would be molecular link for overlapped pathogenesis between MDD and anxiety disorder. MATERIALS AND METHODS: Using long noncoding RNA (lncRNA) microarray profiling and reverse transcription polymerase chain reaction, six downregulated lncRNAs and three upregulated lncRNAs had been identified to be the potential biomarkers for MDD and generalized anxiety disorder (GAD), respectively...
January 2017: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28529139/psychopharmacology-of-combined-activation-of-the-serotonin1a-and-%C3%AF-1-receptors
#9
REVIEW
Yukio Ago, Shigeru Hasebe, Naoki Hiramatsu, Hitoshi Hashimoto, Kazuhiro Takuma, Toshio Matsuda
The selective serotonin (5-HT) reuptake inhibitors (SSRIs) are generally used for the treatment of major depressive disorders, and the 5-HT1A and σ1 receptors are considered to be targets for treatment of psychiatric disorders. Some SSRIs such as fluvoxamine have agonistic activity towards for the σ1 receptor, but it is not known whether the effect on the receptor plays a key role in the pharmacological effects. We have recently demonstrated that fluvoxamine shows an anti-anhedonic effect in picrotoxin-induced model of anxiety/depression, while the SSRI paroxetine, which have little affinity for the σ1 receptor, does not...
May 18, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28528244/heart-rate-variability-of-chronic-posttraumatic-stress-disorder-in-the-korean-veterans
#10
Joo Eon Park, Ji Yeon Lee, Suk-Hoon Kang, Jin Hee Choi, Tae Yong Kim, Hyung Seok So, In-Young Yoon
Patients with post-traumatic stress disorder (PTSD) have lower heart rate variability (HRV) than the general population, but findings in this area have been inconsistent. This study was conducted to investigate the characteristics of HRV in patients with PTSD and to evaluate associations between PTSD symptoms and HRV indices. Sixty-eight patients with PTSD and 73 controls without PTSD were evaluated. HRV was measured in all subjects after they completed self-reported questionnaires. Patients with PTSD had significantly more depressed moods, anxiety, and poorer sleep quality than individuals in the non-PTSD group...
May 9, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28527083/shared-mechanisms-of-epilepsy-migraine-and-affective-disorders
#11
Davide Zarcone, Simona Corbetta
Since the nineteenth century several clinical features have been observed in common between migraine and epilepsy (such as episodic attacks, triggering factors, presence of aura, frequent familiarity), but only in recent years researchers have really engaged in finding a common pathogenic mechanism. From studies of disease incidence, we understand how either migraine among patients with epilepsy or epilepsy among migraine patients are more frequent than in the general population. This association may result from a direct causality, by the same environmental risk factors and/or by a common genetic susceptibility...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28527018/predicting-academic-impairment-and-internalizing-psychopathology-using-a-multidimensional-framework-of-sluggish-cognitive-tempo-with-parent-and-adolescent-reports
#12
Zoe R Smith, Joshua M Langberg
Adolescents with Sluggish Cognitive Tempo (SCT) exhibit symptoms of slowness, mental confusion, excessive daydreaming, low motivation, and drowsiness/sleepiness. Although many symptoms of SCT reflect internalizing states, no study has evaluated the clinical utility of self-report of SCT in an attention-deficit/hyperactivity disorder (ADHD) sample. Furthermore, it remains unclear whether SCT is best conceptualized as a unidimensional or multidimensional construct. In a sample of 262 adolescents comprehensively diagnosed with ADHD, the present study used adolescent- and parent reports of SCT to evaluate the predictive utility of a general SCT factor from a bifactor modeling approach compared the utility of three specific SCT factors (slow, sleepy, and daydreamer) for predicting academic impairment and internalizing psychopathology...
May 19, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28526049/psychological-status-and-quality-of-life-among-primary-caregivers-of-individuals-with-mental-illness-a-hospital-based-study
#13
Anitha Jeyagurunathan, Vathsala Sagayadevan, Edimansyah Abdin, YunJue Zhang, Sherilyn Chang, Saleha Shafie, Restria Fauziana Abdul Rahman, Janhavi Ajit Vaingankar, Siow Ann Chong, Mythily Subramaniam
BACKGROUND: This study aimed to explore the psychological status and quality of life among primary caregivers of individuals suffering from various mental illnesses including early psychosis, chronic schizophrenia, depressive disorders, anxiety disorders and dementia. METHODS: A total of 350 primary caregivers with relatives seeking treatment at a tertiary psychiatric hospital were recruited for this study. Socio-demographic data was obtained and the brief version of the World Health Organisation Quality of Life instrument was used to assess caregiver's quality of life (QOL)...
May 19, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28522342/acute-and-repeated-exposure-with-the-nitric-oxide-no-donor-sodium-nitroprusside-snp-differentially-modulate-responses-in-a-rat-model-of-anxiety
#14
Martha A Orfanidou, Anastasios Lafioniatis, Aikaterini Trevlopoulou, Ntilara Touzlatzi, Nikolaos Pitsikas
The nitric oxide (NO) donor sodium nitroprusside (SNP) actually is under investigation for the treatment of schizophrenia. That anxiety disorders are noted to occur commonly in schizophrenia patients is known. Contradictory results were reported however, concerning the effects of SNP in animal models of anxiety disorders. The present study investigated the effects of acute and repeated administration of SNP on anxiety-like behaviour in rats assessed in the light/dark test. The effects of SNP on motility in a locomotor activity chamber were also investigated in rats...
May 15, 2017: Nitric Oxide: Biology and Chemistry
https://www.readbyqxmd.com/read/28522289/epidemiology-of-pain-and-relation-to-psychiatric-disorders
#15
REVIEW
Ana Miriam Velly, Shrisha Mohit
Chronic pain is a common pain condition. Some psychiatric disorders, such as anxiety and depression, are also common in the general population. Epidemiological studies found that some psychiatric disorders are more commonly found among persons with chronic pain (e.g., headache, back pain) than those without chronic pain. Why those psychiatric disorders co-occur with chronic pain, however, is not well understood. Further, studies demonstrated that some psychiatric disorders, such as depression, increase the risk of chronic pain as well as its persistence...
May 15, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28517947/intolerance-of-uncertainty-predicts-increased-striatal-volume
#16
M Justin Kim, Jin Shin, James M Taylor, Alison M Mattek, Samantha J Chavez, Paul J Whalen
Oversensitivity to uncertain future threat is usefully conceptualized as intolerance of uncertainty (IU). Neuroimaging studies of IU to date have largely focused on its relationship with brain function, but few studies have documented the association between IU and the quantitative properties of brain structure. Here, we examined potential gray and white-matter brain structural correlates of IU from 61 healthy participants. Voxel-based morphometric analysis highlighted a robust positive correlation between IU and striatal volume, particularly the putamen...
May 18, 2017: Emotion
https://www.readbyqxmd.com/read/28515551/combining-metacognitive-strategies-with-traditional-cognitive-behavior-therapy-in-generalized-anxiety-disorder-a-case-illustration
#17
Paulomi M Sudhir, Systla Rukmini, Mahendra Prakash Sharma
CONTEXT: Generalized anxiety disorder (GAD) is a challenging clinical condition to manage. Recent psychological models of GAD emphasis on the need to focus on metacognitive processes in addition to symptom reduction. AIMS: We examined the application of metacognitive strategies in addition to conventional cognitive behaviour therapy (CBT) techniques in an adult patient with GAD. SETTINGS AND DESIGNS: Asingle case design with pre- and post-assessments on clinician-rated scales was adopted...
March 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28515545/traumatic-brain-injury-and-neuropsychiatric-complications
#18
REVIEW
Saeed Ahmed, Hema Venigalla, Hema Madhuri Mekala, Sara Dar, Mudasar Hassan, Shahana Ayub
Traumatic brain injury (TBI) occurs when a blow or jolt to the head or a penetrating injury results in damage to the brain. It is the most frequent cause of hospitalization in young people with a higher prevalence in men. TBI is the leading cause of disability and mortality between the ages 1 and 45. TBI can be caused either by the direct result of trauma or due to a complication of the primary injury. The most common etiological factors for TBI are falls, road traffic accidents, violent physical assaults, and injuries associated with athletic activities...
March 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28514334/-anxiety-and-depressive-disorders-in-parkinson-s-disease
#19
G N Akhmadeeva, R V Magzhanov, G N Tayupova, A R Bajtimerov, I M Hidijatova
This review presents the most recent data of worldwide research on anxiety and depressive disorders in patients with Parkinson's disease. Their characteristics and epidemiology, pathogenetic and clinical features, methods of diagnosis and treatment are presented. Depression occurs in 40-50% of patients with PD, anxiety in 17-43% of patients. Pramipexole, a dopamine agonist, is only one drug recommended for depression treatment. Nortriptyline and desipramine, belonging to the group of tricyclic antidepressants (TCAs), are considered to be possibly effective...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28513195/binge-drinking-health-impact-prevalence-correlates-and-interventions
#20
Emmanuel Kuntsche, Sandra Kuntsche, Johannes Thrul, Gerhard Gmel
OBJECTIVE: Binge drinking (also called heavy episodic drinking, risky single-occasion drinking etc.) is a major public health problem. This paper provides an overview of recently published evidence concerning the definition and measurement, prevalence rates, health impact, demographic and psychosocial correlates of, and interventions for, binge drinking. DESIGN: Narrative review. RESULTS: Mostly occurring among young people at weekends, binge drinking increases the risk of both acute (e...
May 17, 2017: Psychology & Health
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