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REVIEW
Sabrina E Racine-Brzostek, Melissa M Cushing, Michelle Gareis, Andrea Heger, Trupti Mehta Shah, Marie Scully
No abstract text is available yet for this article.
April 21, 2024: Transfusion
#22
REVIEW
Thomas Vetsch, Sabrina Eggmann, François Jardot, Marc von Gernler, Dominique Engel, Christian M Beilstein, Patrick Y Wuethrich, Prisca Eser, Matthias Wilhelm
BACKGROUND: Major surgery is associated with high complication rates. Several risk scores exist to assess individual patient risk before surgery but have limited precision. Novel prognostic factors can be included as additional building blocks in existing prediction models. A candidate prognostic factor, measured by cardiopulmonary exercise testing, is ventilatory efficiency (VE/VCO2 ). The aim of this systematic review was to summarise evidence regarding VE/VCO2 as a prognostic factor for postoperative complications in patients undergoing major surgery...
April 20, 2024: British Journal of Anaesthesia
#23
JOURNAL ARTICLE
Sabrina Ignacio, Jonatan Schlotthauer, Mirna Sigrist, Alejandra V Volpedo, Gustavo A Thompson
Micropogonias furnieri and Urophycis brasiliensis are two coastal demersal fish species distributed in the southwestern Atlantic Ocean. Considering that many coastal areas in the southwestern Atlantic Ocean suffer from anthropogenic pressure, the aim of this study was to assess the level of potentially toxic trace elements (Ag, Al, As, Cd, Co, Cr, Cu, Fe, Hg, Mn, Mo, Ni, Pb, Se, Sr, V and Zn) in the muscle of coastal species, and evaluated the human health risk related to the consumption of muscle. Mercury, inorganic As (Asi ), V, and Se showed a higher contribution to the total THQ...
April 20, 2024: Marine Pollution Bulletin
#24
JOURNAL ARTICLE
Vladimira Hinić, Helena M B Seth-Smith, Sabrina Stammler, Adrian Egli
Current methods for plasmid-mediated AmpC β-lactamase (pAmpC) detection in routine microbiological laboratories are based on various phenotypic tests. Eazyplex®SuperBug AmpC assay is a molecular assay based on isothermal amplification for rapid detection of the most common pAmpC types from bacterial culture: CMY-2 group, DHA, ACC and MOX. Our aim was to evaluate the diagnostic performance of this assay. The assay was evaluated on 64 clinical isolates of Enterobacterales without chromosomal inducible AmpC, and with phenotypically confirmed AmpC production...
April 18, 2024: Journal of Microbiological Methods
#25
JOURNAL ARTICLE
Warda Sidhoum, Soulef Dib, Yousra Alim, Sarra Anseur, Sabrina Benlatreche, Zoulikha Mouna Belaidouni, Fatiha El Zahra Chamouma
Cucurbits are subject to a variety of stresses that limit their sustainable production, despite their important role in ensuring food security and nutrition. Plant stress tolerance can be enhanced through fungal endophytes. In this study, two endophytes isolated from wild plant roots, were tested to determine their effect on the growth promotion of cucumber (Cucumis sativus L.) plants. The phylogenetic analysis revealed that the designated isolates were Aspergillus elegans and Periconia macrospinosa. The results of the Plant Growth Promoting Fungal (PGPF) tests showed that both Aspergillus elegans and Periconia macrospinosa have a zinc solubilizing capacity, especially A...
April 20, 2024: Archives of Microbiology
#26
JOURNAL ARTICLE
C-N Alexandrina Guran, Magdalena Boch, Ronald Sladky, Lucrezia Lonardo, Sabrina Karl, Ludwig Huber, Claus Lamm
Dogs are increasingly used as a model for neuroscience due to their ability to undergo functional MRI fully awake and unrestrained, after extensive behavioral training. Still, we know rather little about dogs' basic functional neuroanatomy, including how basic perceptual and motor functions are localized in their brains. This is a major shortcoming in interpreting activations obtained in dog fMRI. The aim of this preregistered study was to localize areas associated with somatosensory processing. To this end, we touched N = 22 dogs undergoing fMRI scanning on their left and right flanks using a wooden rod...
April 20, 2024: Brain Structure & Function
#27
JOURNAL ARTICLE
Colin R Zamecnik, Gavin M Sowa, Ahmed Abdelhak, Ravi Dandekar, Rebecca D Bair, Kristen J Wade, Christopher M Bartley, Kerry Kizer, Danillo G Augusto, Asritha Tubati, Refujia Gomez, Camille Fouassier, Chloe Gerungan, Colette M Caspar, Jessica Alexander, Anne E Wapniarski, Rita P Loudermilk, Erica L Eggers, Kelsey C Zorn, Kirtana Ananth, Nora Jabassini, Sabrina A Mann, Nicholas R Ragan, Adam Santaniello, Roland G Henry, Sergio E Baranzini, Scott S Zamvil, Joseph J Sabatino, Riley M Bove, Chu-Yueh Guo, Jeffrey M Gelfand, Richard Cuneo, H-Christian von Büdingen, Jorge R Oksenberg, Bruce A C Cree, Jill A Hollenbach, Ari J Green, Stephen L Hauser, Mitchell T Wallin, Joseph L DeRisi, Michael R Wilson
Although B cells are implicated in multiple sclerosis (MS) pathophysiology, a predictive or diagnostic autoantibody remains elusive. In this study, the Department of Defense Serum Repository (DoDSR), a cohort of over 10 million individuals, was used to generate whole-proteome autoantibody profiles of hundreds of patients with MS (PwMS) years before and subsequently after MS onset. This analysis defines a unique cluster in approximately 10% of PwMS who share an autoantibody signature against a common motif that has similarity with many human pathogens...
April 19, 2024: Nature Medicine
#28
JOURNAL ARTICLE
Sabrina Douglas, Gerarda Darlington, Kirsten Davison, John Beaton, Jess Haines
Parents have primary influence over the development of their children's eating behaviours, however less attention has been given to whether or how their coparenting plays a role in this association. The aim of this study was to investigate the cross-sectional associations between mothers' and fathers' food parenting practices and children's eating behaviour and examine whether coparenting quality moderates or confounds these associations. Parents (222 mothers and 167 fathers) with children 18 months to 5 years completed an online survey that assessed their food parenting practices and coparenting quality...
April 17, 2024: Appetite
#29
JOURNAL ARTICLE
Simona Salerno, Antonella Piscioneri, Sabrina Morelli, Alessandro Gori, Elena Provasi, Paola Gagni, Lucio Barile, Marina Cretich, Marcella Chiari, Loredana De Bartolo
Recently, membrane devices and processes have been applied for the separation and concentration of subcellular components such as extracellular vesicles (EVs), which play a diagnostic and therapeutic role in many pathological conditions. However, the separation and isolation of specific EV populations from other components found in biological fluids is still challenging. Here, we developed a peptide-functionalized hollow fiber (HF) membrane module to achieve the separation and enrichment of highly pure EVs derived from the culture media of human cardiac progenitor cells...
April 12, 2024: Journal of Colloid and Interface Science
#30
JOURNAL ARTICLE
Aaron M Etra, Najla El Jurdi, Nikolaos Katsivelos, Deukwoo Kwon, Stephanie C Gergoudis, George Morales, Nikolaos Spyrou, Steven Kowalyk, Paibel Aguayo-Hiraldo, Yu Akahoshi, Francis Ayuketang Ayuk, Janna Baez, Brian C Betts, Chantiya Chanswangphuwana, Yi-Bin Chen, Hannah K Choe, Zachariah DeFilipp, Sigrun Gleich, Elizabeth O Hexner, William J Hogan, Ernst Holler, Carrie L Kitko, Sabrina Kraus, Monzr M Al Malki, Margaret L MacMillan, Attaphol Pawarode, Francesco Quagliarella, Muna Qayed, Ran Reshef, Tal Schechter-Finkelstein, Ingrid Vasova, Daniel J Weisdorf, Matthias Wölfl, Rachel Young, Ryotaro Nakamura, James L M Ferrara, John E Levine, Shernan G Holtan
Graft-vs-host disease (GVHD) is a major cause of non-relapse mortality (NRM) following allogeneic hematopoietic cell transplant (HCT). Algorithms containing either the GI GVHD biomarker amphiregulin (AREG) or a combination of two GI GVHD biomarkers, (ST2+REG3α) when measured at GVHD diagnosis are validated predictors of NRM risk, but have never been assessed in the same patients using identical statistical methods. We measured serum concentrations of ST2, REG3, and AREG by ELISA at the time of GVHD diagnosis in 715 patients divided by date of transplant into training (2004-2015) and validation (2015-2017) cohorts...
April 19, 2024: Blood Advances
#31
JOURNAL ARTICLE
Maria Gori, Clara Fappani, Silvia Bianchi, Sabrina Senatore, Daniela Colzani, Priscilla Pasutto, Melissa Baggieri, Silvia Gioacchini, Antonella Marchi, Paola Bucci, Emilio D'Ugo, Marino Faccini, Danilo Cereda, Luigi Vezzosi, Elisabetta Tanzi, Fabio Magurano, Antonella Amendola
Since late 2023, the Metropolitan City of Milan and surrounding areas (northern Italy) have been experiencing a resurgence of measles, with most cases detected starting from January 2024. During this brief period, we observed measles in travellers from endemic areas, participants in international events, vaccinees and healthcare workers. Indigenous cases have also been identified. Even though we have not yet identified large and disruptive outbreaks, strengthening surveillance and vaccination activities is pivotal to help limit the impact of measles spread...
April 2024: Euro Surveillance
#32
JOURNAL ARTICLE
Richard O Kopp, Sabrina L Kleynemeyer, Lucie J Groth, Moritz J Ernst, Susanne M Rupf, Manuela Weber, Laurence J Kershaw Cook, Nathan T Coles, Samuel E Neale, Christian Müller
Tetrapyridyl-functionalized phosphinines were prepared and structurally characterized. The donor-functionalized aromatic phosphorus heterocycles react highly selectively and even reversibly with water. Calculations reveal P,N-cooperativity for this process, with the flanking pyridyl groups serving to kinetically enhance the formal oxidative addition process of H2 O to the low-coordinate phosphorus atom via H-bonding. Subsequent tautomerization forms 1,2-dihydrophosphinine derivatives, which can be quantitatively converted back to the phosphinine by applying vacuum, even at room temperature...
April 17, 2024: Chemical Science
#33
JOURNAL ARTICLE
Lucia Pedace, Simone Pizzi, Luana Abballe, Maria Vinci, Celeste Antonacci, Sara Patrizi, Claudia Nardini, Francesca Del Bufalo, Sabrina Rossi, Giulia Pericoli, Francesca Gianno, Zein Mersini Besharat, Luca Tiberi, Angela Mastronuzzi, Elisabetta Ferretti, Marco Tartaglia, Franco Locatelli, Andrea Ciolfi, Evelina Miele
In vitro models of pediatric brain tumors (pBT) are instrumental for better understanding the mechanisms contributing to oncogenesis and testing new therapies; thus, ideally, they should recapitulate the original tumor. We applied DNA methylation (DNAm) and copy number variation (CNV) profiling to characterize 241 pBT samples, including 155 tumors and 86 pBT-derived cell cultures, considering serum vs serum-free conditions, late vs early passages, and dimensionality (2D vs 3D cultures). We performed a t-SNE classification and identified differentially methylated regions in tumors compared to cell models...
April 18, 2024: NPJ Precision Oncology
#34
JOURNAL ARTICLE
Cosima Jahnke, Angeliki Darma, Frank Lindemann, Sabrina Oebel, Sebastian Hilbert, Kerstin Bode, Christian Stehning, Jouke Smink, Ingo Paetsch
Fully CMR-guided electrophysiological interventions (EP-CMR) have recently been introduced but data on the optimal CMR imaging protocol are scarce. This study determined the clinical utility of 3D non-selective whole heart steady-state free precession imaging using compressed SENSE (nsWHcs) for automatic segmentation of cardiac cavities as the basis for targeted catheter navigation during EP-CMR cavo-tricuspid isthmus ablation. Fourty-two consecutive patients with isthmus-dependent right atrial flutter underwent EP-CMR radiofrequency ablations...
April 18, 2024: Scientific Reports
#35
JOURNAL ARTICLE
Silvia Guiducci, Giulia Res, Luca Bonadies, Federica Savio, Sabrina Brigadoi, Elena Priante, Daniele Trevisanuto, Eugenio Baraldi, Alfonso Galderisi
Nutritional intake could influence the blood glucose profile during early life of preterm infants. We investigated the impact of macronutrient intake on glycemic homeostasis using continuous glucose monitoring (CGM). We analyzed macronutrient intake in infants born ≤ 32 weeks gestational age (GA) and/or with birth weight ≤ 1500 g. CGM was started within 48 h of birth and maintained for 5 days. Mild and severe hypoglycemia were defined as sensor glucose (SG) < 72 mg/dL and <47 mg/dL, respectively, while mild and severe hyperglycemia were SG > 144 mg/dL and >180 mg/dL...
April 18, 2024: European Journal of Pediatrics
#36
JOURNAL ARTICLE
María V Fraga, Holly L Hedrick, Natalie E Rintoul, Yan Wang, Devon Ash, Sabrina J Flohr, Leny Mathew, Tom Reynolds, Jenny L Engelman, Catherine M Avitabile
OBJECTIVES: To describe the scope of left ventricular (LV) dysfunction and left heart hypoplasia (LHH) in infants with congenital diaphragmatic hernia (CDH), to determine associations with CDH severity, and to evaluate the odds of extracorporeal membrane oxygenation (ECMO) and death with categories of left heart disease. STUDY DESIGN: Demographic and clinical variables were collected from a single-center, retrospective cohort of CDH patients from January 2017 through May 2022...
April 16, 2024: Journal of Pediatrics
#37
REVIEW
Angela T H Kwan, Kayla M Teopiz, Sabrina Wong, Joshua D Rosenblat, Rodrigo B Mansur, Taeho Greg Rhee, Roger Ho, Bing Cao, Roger S McIntyre
BACKGROUND: Ketamine has been established as efficacious in adults living with Treatment-resistant Depression (TRD). Toward providing a quantifiable estimate of the clinical meaningfulness of the therapeutic benefit of ketamine, herein, we conduct a systematic review that aims to report the Number Needed to Treat (NNT) and the Number Needed to Harm (NNH). METHODS: This systematic review searched Embase, Medline/Pubmed, PsycINFO and ClinicalTrials.gov from inception up to October 15th 2023, for placebo-controlled, Randomized Controlled Trials (RCTs) assessing racemic ketamine or esketamine therapy for unipolar TRD...
April 16, 2024: Journal of Affective Disorders
#38
JOURNAL ARTICLE
Silvia Ricci, Valentina Guarnieri, Francesca Capitanini, Caterina Pelosi, Valeria Astorino, Silvia Boscia, Elisa Calistri, Clementina Canessa, Martina Cortimiglia, Francesca Lippi, Lorenzo Lodi, Sabrina Malvagia, Maria Moriondo, Giancarlo La Marca, Chiara Azzari
BACKGROUND: Inborn errors of immunity (IEIs) include 485 inherited disorders characterized by an increased susceptibility to life threatening infectious diseases, autoimmunity and malignant diseases with a high mortality rate in the first years of life. Severe Combined Immunodeficiency is the most severe of the IEIs and its detection should be a primary goal in a newborn screening (NBS) program. The term "actionable" has recently been used for all IEIs with outcomes that can be demonstrably improved through early specialized intervention...
April 16, 2024: Journal of Allergy and Clinical Immunology in Practice
#39
JOURNAL ARTICLE
Marta Cunha, Alessandro Nardi, Maria João Botelho, Sabrina Sales, Eduarda Pereira, Amadeu M V M Soares, Francesco Regoli, Rosa Freitas
The presence in marine shellfish of toxins and pollutants like rare earth elements (REEs) poses a major threat to human well-being, coastal ecosystems, and marine life. Among the REEs, neodymium (Nd) stands out as a widely utilized element and is projected to be among the top five critical elements by 2025. Gymnodinum catenatum is a phytoplankton species commonly associated with the contamination of bivalves with paralytic shellfish toxins. This study evaluated the biological effects of Nd on the mussel species Mytilus galloprovincialis when exposed to G...
April 4, 2024: Journal of Hazardous Materials
#40
JOURNAL ARTICLE
Laura D Zambrano, Margaret M Newhams, Regina M Simeone, Amanda B Payne, Michael Wu, Amber O Orzel-Lockwood, Natasha B Halasa, Jemima M Calixte, Pia S Pannaraj, Kanokporn Mongkolrattanothai, Julie A Boom, Leila C Sahni, Satoshi Kamidani, Kathleen Chiotos, Melissa A Cameron, Aline B Maddux, Katherine Irby, Jennifer E Schuster, Elizabeth H Mack, Austin Biggs, Bria M Coates, Kelly N Michelson, Katherine E Bline, Ryan A Nofziger, Hillary Crandall, Charlotte V Hobbs, Shira J Gertz, Sabrina M Heidemann, Tamara T Bradford, Tracie C Walker, Stephanie P Schwartz, Mary Allen Staat, Samina S Bhumbra, Janet R Hume, Michele Kong, Melissa S Stockwell, Thomas J Connors, Melissa L Cullimore, Heidi R Flori, Emily R Levy, Natalie Z Cvijanovich, Matt S Zinter, Mia Maamari, Cindy Bowens, Danielle M Zerr, Judith A Guzman-Cottrill, Ivan Gonzalez, Angela P Campbell, Adrienne G Randolph
Pediatric COVID-19 vaccination is effective in preventing COVID-19-related hospitalization, but duration of protection of the original monovalent vaccine during SARS-CoV-2 Omicron predominance merits evaluation, particularly given low coverage with updated COVID-19 vaccines. During December 19, 2021-October 29, 2023, the Overcoming COVID-19 Network evaluated vaccine effectiveness (VE) of ≥2 original monovalent COVID-19 mRNA vaccine doses against COVID-19-related hospitalization and critical illness among U...
April 18, 2024: MMWR. Morbidity and Mortality Weekly Report
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