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https://www.readbyqxmd.com/read/27867576/resection-with-preserved-histologic-morphology-of-a-rare-tumour-via-bronchoscopic-cryosurgery
#1
Jessica Han Ying Tan, Angela Maria Takano, Anne Ann Ling Hsu
Tracheobronchial leiomyoma is a rare pulmonary neoplasm accounting for <2% of benign tumours of the lower airway. Published case series reported bronchoscopic resectability with laser ablation for lesions located in the large airway. Surgery was performed for tumours with wide-based and tumours located in segmental bronchus or lung parenchyma. This is the first reported case of complete bronchoscopic cryoresection of leiomyoma arising from the subsegmental bronchi and illustrating the cryopreservation of its histologic morphology...
October 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27792269/impaired-immunosuppressive-effect-of-bronchoalveolar-mesenchymal-stem-cells-in-hypersensitivity-pneumonitis-preliminary-findings
#2
Enikő Balogh, Béla Nagy, Ágnes Gyetvai, Zsolt Bene, Zoltán Hendrik, Viktória Jeney, Péter Nagy, Ágnes Papp, József Balla, György Balla, János Kappelmayer, Béla Nagy
BACKGROUND: Bronchoalveolar mesenchymal stem cells (MSCs) play an important role in the maintenance of lung integrity. Therapeutic application of bone marrow-derived MSCs reduced chronic bronchial inflammation in idiopathic pulmonary fibrosis, and improved the ratio of survivors in sepsis with pneumonia. This study investigated the effect of MSCs from bronchoalveolar lavage fluid (BALF) of hypersensitivity pneumonitis (HP) on T-cell function under in vitro conditions. METHODS: Bronchoalveolar MSCs were obtained via bronchoscopy with BAL from children with severe subacute HP...
October 28, 2016: Cytometry. Part B, Clinical Cytometry
https://www.readbyqxmd.com/read/27594885/tracheobronchial-amyloidosis-mimicking-tracheal-tumor
#3
Elif Tanrıverdi, Mehmet Akif Özgül, Oğuz Uzun, Şule Gül, Mustafa Çörtük, Zehra Yaşar, Murat Acat, Naciye Arda, Erdoğan Çetinkaya
Tracheobronchial amyloidosis is a rare presentation and accounts for about 1% of benign tumors in this area. The diagnosis of disease is delayed due to nonspecific pulmonary symptoms. Therapeutic approaches are required to control progressive pulmonary symptoms for most of the patients. Herein, we report a case of a 68-year-old man admitted with progressive dyspnea to our institution for further evaluation and management. He was initially diagnosed with and underwent management for bronchial asthma for two years but had persistent symptoms despite optimal medical therapy...
2016: Case Reports in Medicine
https://www.readbyqxmd.com/read/27493804/high-dose-rate-brachytherapy-as-a-treatment-option-in-endobronchial-tumors
#4
Ali Hosni, Andrea Bezjak, Alexandra Rink, Kasia Czarnecka, Andrew McPartlin, Susan Patterson, Elantholiparameswaran Saibishkumar
Purpose. To report our experience with high dose rate endobronchial brachytherapy (HDR-EBBT) and to assess its efficacy and tolerability with possibility of its use in selected cases with curative intent. Method. Retrospective review of patients with endobronchial tumors treated at our institution in 2007-2013 with HDR-EBBT. Subjective response and treatment related toxicity were extracted from patients' records. Clinical response was evaluated by chest CT +/- bronchoscopy 2-3 months after treatment. Local control (LC) and overall survival (OS) were analyzed...
2016: Lung Cancer International
https://www.readbyqxmd.com/read/27487178/the-molecular-bronchoscope-a-tool-for-measurement-of-spatially-dependent-co2-concentrations-in-the-lungs
#5
Luca Ciaffoni, John H Couper, Graham Richmond, Gus Hancock, Grant A D Ritchie
Respiratory physicians use bronchoscopy for visual assessment of the lungs' topography and collecting tissue samples for external analysis. We propose a novel bronchoscope tool that would enable spatially dependent measurements of the functioning of the lungs by determining local concentrations of carbon dioxide, which will be produced by healthy parts of the lung at rates that are higher than from portions where gas exchange is impaired. The gas analyzer is based on a compact laser absorption spectrometer making use of fiber optics for delivery and return of low intensity diode laser radiation to and from the measurement chamber at the distal end of a flexible conduit...
September 6, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/27446391/endobronchial-fibroma-in-a-pneumoconiosis-patient-with-a-history-of-tuberculosis-a-case-report-and-literature-review
#6
Meifang Wang, Yuquan Liu, Dan Li, Chang Xiong, Xin Qian, Yijun Tang
Bronchial fibroma is uncommon, with only 18 cases reported since 1948. The current study presents a rare case of endobronchial fibroma, along with a relevant literature review. A 54-year-old male patient with pneumoconiosis and a history of tuberculosis was admitted to the Taihe Hospital Affiliated With Hubei University of Medicine, Shiyan, China, due to refractory dry cough. Computed tomography of the chest showed multiple nodular and confluent opacities in the lung and one cavitation in the right upper lobe region...
August 2016: Oncology Letters
https://www.readbyqxmd.com/read/27440036/-photodynamic-therapy-for-lung-cancer
#7
Keishi Ohtani, Norihiko Ikeda
In Japan, Photodynamic therapy (PDT) is recommended as a treatment option for centrally located early-stage lung cancers (CLELCs). It is a minimally invasive treatment with excellent anti-tumor effects. The 2nd generation photosensitizer, talaporfin sodium has strong anti-tumor effects with much less photosensitivity than porfimer sodium. Moreover, the laser equipment is compact and portable, and talaporfin sodium is now the current mainstay of PDT for lung cancer. For successful PDT, accurate evaluation of tumor extent and bronchial invasion is crucial...
July 2016: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/27362271/usefulness-of-bronchoscopic-probe-based-confocal-laser-endomicroscopy-in-the-diagnosis-of-pneumocystis-jirovecii-pneumonia
#8
Hanaa Shafiek, Federico Fiorentino, Borja G Cosio, Ana Kersul, Luc Thiberville, Cristina Gómez, Melchor Riera, Maria L Martín, Rocio Martínez, Maria A Noguera, Alvar Agustí, Jaume Sauleda
BACKGROUND: Probe-based confocal laser endomicroscopy (pCLE) is a novel technique that provides in vivo microscopic imaging of the distal lung. We hypothesized that the intra-alveolar exudates characterizing Pneumocystis jirovecii pneumonia (PJP) can be identified by pCLE in vivo and help in its diagnosis. OBJECTIVES: We aimed to assess the usefulness of pCLE for the in vivo diagnosis of PJP. METHODS: Thirty-two human immunodeficiency virus (HIV)-positive patients with new pulmonary infiltrates and fever were studied using pCLE...
2016: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/27290957/air-q-laryngeal-airway-for-rescue-and-tracheal-intubation
#9
Ayman Ads, Frederic Auerbach, Kelly Ryan, Abdel R El-Ganzouri
We report the successful use of the Air-Q laryngeal airway (Air-Q LA) as a ventilatory device and a conduit for tracheal intubation to rescue the airway in a patient with difficult airway and tracheal stenosis. This is the first case report of the device to secure the airway after two episodes of hypoxemia in the operating room and intensive care unit. Consent for submission of this case report was obtained from our institution's human studies institutional review board given that the patient died a few months after his discharge from the hospital before his personal consent could be obtained and before preparation of this report...
August 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27022925/respiratory-conditions-associated-with-tracheobronchomegaly-mounier-kuhn-syndrome-a-study-of-seventeen-cases
#10
Pierre Schmitt, Levent Dalar, Stéphane Jouneau, Bénédicte Toublanc, Juliette Camuset, Gérard Chatte, Laurent Cellerin, Hervé Dutau, Stéphane Sanchez, Maxime Sauvage, Jean-Michel Vergnon, Sandra Dury, Gaetan Deslée, François Lebargy
BACKGROUND: Mounier-Kuhn syndrome (MKS) is a rare disorder characterized by enlargement of the trachea and main bronchi and associated with recurrent respiratory tract infections. OBJECTIVE: This multicenter, retrospective study was carried out to describe respiratory conditions associated with tracheobronchomegaly. METHODS: Nine institutions involved in the 'Groupe d'Endoscopie de Langue Française' (GELF) participated in this study. A standard form was used to record patient characteristics, treatments and follow-up from medical charts...
2016: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/27006182/a-new-endoscopic-hand-drill-for-management-of-tracheal-stenosis
#11
Sandro Batzella, Gabriele Lucantoni, Alfonso Fiorelli, Raffaele Dello Iacono, Paolo Battistoni, Umberto Caterino, Mario Santini, Giovanni Galluccio
Tracheal resection and primary anastomosis is the treatment of choice for the management of benign tracheal stenoses. Rigid endoscopy with laser-assisted mechanical dilatation is an alternative to surgery and helps to improve symptoms and quality of life in patients unfit for surgery. Here, we describe the treatment of a simple web-like stenosis, using a new endoscopic hand drill that was assembled by sharpening the blunt tip of a standard endoscopic cotton applicator. The bronchoscopy was positioned proximally to the stenotic lesion and radial holes were made at 12, 3 and 9 o'clock...
July 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/26286177/the-tools-of-the-trade-uses-of-flexible-bronchoscopy
#12
Varinder Singh, Kamal Kumar Singhal
Bronchoscopes have markedly improved the diagnosis as well as therapy in pediatric pulmonary disorders. Two types of bronchoscopes are available; flexible and rigid, with their own advantages and disadvantages. Depending on the clinical need and availability of skills, choice is made between the two. Typically, rigid scopes are largely used by the surgeons (pediatric or otolayngologists) while flexible bronchoscope stays in the domain of the pediatric pulmonologist and intensivists. Rigid scopes may be more versatile than flexible bronchoscopes in removing the foreign bodies from the airway...
October 2015: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/26216723/a-novel-method-for-in-vivo-imaging-of-solitary-lung-nodules-using-navigational-bronchoscopy-and-confocal-laser-microendoscopy
#13
T Hassan, N Piton, S Lachkar, M Salaün, L Thiberville
Solitary pulmonary nodules (SPN) have become increasingly prevalent and diagnostic management remains challenging. We demonstrate a novel technique in which probe-based confocal endomicroscopy (pCLE) could be performed to microimage SPN in vivo and in real-time. Two confocal wavelengths (488 and 660 nm with methylene blue (MB)) were used for elastin network and cellular imaging, respectively using pCLE in conjunction with r-EBUS and virtual navigation. In the first case, the 1-mm Alveoflex was used to image a metastatic melanoma in a subcentimetric nodule in the right middle lobe...
October 2015: Lung
https://www.readbyqxmd.com/read/26094505/comparison-of-in-vivo-probe-based-confocal-laser-endomicroscopy-with-histopathology-in-lung-cancer-a-move-toward-optical-biopsy
#14
COMPARATIVE STUDY
Adam S Wellikoff, Robert C Holladay, Gordon H Downie, Catherine S Chaudoir, Luis Brandi, Elba A Turbat-Herrera
BACKGROUND AND OBJECTIVE: The development of novel technologies has increased the yield from transbronchial biopsies while preserving patient safety by guiding biopsies to the area of interest. Other technologies have helped identify pre-cancerous or sessile lesions in the endobronchial space by utilizing interactions between tissue and light at varying wavelengths. Probe-based confocal laser endomicroscopy (pCLE) is a new technology that encompasses the benefits of both guided biopsies and novel optical imaging in one device...
August 2015: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/25965540/historical-perspectives-of-bronchoscopy-connecting-the-dots
#15
Tanmay S Panchabhai, Atul C Mehta
The era of bronchoscopy began with Gustav Killian in 1876 when he removed a pork bone from a farmer's airway, using an esophagoscope. Prompted by this accomplishment, Chevalier Jackson, an American otolaryngologist, laid the platform for the modern-day rigid bronchoscope in the early twentieth century. In 1967 Shigeto Ikeda revolutionized the field of bronchoscopy by his innovation of the fiberoptic bronchoscope. Today, bronchoscopy and interventional pulmonology have become an integral part of pulmonary medicine and an established subspecialty...
May 2015: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/25940429/bronchoscopic-procedures-and-lung-biopsies-in-pediatric-lung-transplant-recipients
#16
REVIEW
Jackson Y Wong, Glen P Westall, Gregory I Snell
Bronchoscopy remains a pivotal diagnostic and therapeutic intervention in pediatric patients undergoing lung transplantation (LTx). Whether performed as part of a surveillance protocol or if clinically indicated, fibre-optic bronchoscopy allows direct visualization of the transplanted allograft, and in particular, an assessment of the patency of the bronchial anastomosis (or tracheal anastomosis following heart-lung transplantation). Additionally, bronchoscopy facilitates differentiation of infective processes from rejection episodes through collection and subsequent assessment of bronchoalveolar lavage (BAL) and transbronchial biopsy (TBBx) samples...
December 2015: Pediatric Pulmonology
https://www.readbyqxmd.com/read/25831178/chest-radiography-does-not-alter-the-treatment-course-for-children-after-rigid-bronchoscopy
#17
Matthew L Stone, John D Tillou, Christopher A Guidry, Sara K Rasmussen, Bartholomew J Kane, Eugene D McGahren, Bradley M Rodgers
The purpose of this study was to evaluate the usefulness of chest radiography in the direction of postbronchoscopy clinical therapy. From 2001 to 2011, 368 rigid bronchoscopies were performed at a single institution in 221 children. Indications for bronchoscopy, concomitant bronchoscopic procedures, and results of postoperative chest radiography were evaluated. Rigid bronchoscopy was performed in children at a median age of 2.21 years (range, two days to 20 years). Chest radiography was performed at the discretion of the primary surgeon after 275 (74...
April 2015: American Surgeon
https://www.readbyqxmd.com/read/25763237/iatrogenic-aspiration-of-custom-made-keel-a-case-report
#18
Hadi Sharouny, Rahmat Bin Omar
INTRODUCTION: Laryngeal stenosis has various causes and treatment options. Endoscopic resection of the stenotic part with CO2 laser is one of the treatment options of laryngotracheal stenosis. Keels are useful for preventing adhesion formation, restenosis and web formation, which may happen during the later stage. They can be put in place either via the endoscopic approach or through a micro thyroidotomy and are held in place with a heavy suture through cricothyroid and thyrohyoid membranes...
December 2014: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/25590487/endobronchial-glomus-tumor
#19
Muhammad R S Rashid Ali, Kunji K S Kannan
We report a case of a 52-year-old patient who had undergone a bladder resection and an ileal conduit for a transitional cell carcinoma. He then presented with a short history of hemoptysis 3 months later. Rigid bronchoscopy was performed revealing an endobronchial lesion, which was removed via laser and debulking method without complications. Histopathologic examination confirmed it to be a benign endobronchial glomus tumor. On the basis of our literature search, this is the 34th reported case of glomus tumor arising from the respiratory tract, seventh reported case of an endobronchial glomus tumor treated bronchoscopically, and the first possibly coincidental finding in relation to a patient with primary transitional bladder cell carcinoma...
January 2015: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/25590482/critical-airway-obstruction-challenges-in-airway-management-and-ventilation-during-therapeutic-bronchoscopy
#20
Andreas Espinoza, Kirill Neumann, Per Steinar Halvorsen, Arve Sundset, Johny Kongerud, Erik Fosse
BACKGROUND: Endobronchial interventions are used to alleviate symptoms of airway stenosis. The ventilatory management may be challenging during these procedures, and may influence the choice of airway device. We report our experiences from 902 procedures. METHODS: Patients undergoing interventional bronchoscopy procedures were consecutively registered from 1999 to 2012. Critical airway obstruction (CAO) was defined as stridor, tracheal diameter <5 mm, stenosis of both the main bronchi, or clots/tumor fragments occluding the trachea or both main bronchi...
January 2015: Journal of Bronchology & Interventional Pulmonology
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