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https://www.readbyqxmd.com/read/28329273/is-surgical-resection-superior-to-bronchoscopic-resection-in-patients-with-symptomatic-endobronchial-hamartoma
#1
Sarah M Abdel Hady, Salma E Elbastawisy, Aly S Hassaballa, Hany H Elsayed
A best evidence topic was written according to a structured protocol. The question addressed was: in surgically fit patients with biopsy proven symptomatic endobronchial hamartoma (EH), is surgical resection superior to bronchoscopic resection in terms of outcome. A total of 756 articles were identified using the reported search, of which 8 represented the best evidence to answer the clinical question. The authors, date, journal, country, study type, population, outcomes and key results are tabulated. Three studies included patients who had either bronchoscopic or surgical treatment of EH in the same study...
February 17, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28286654/it-s-better-to-be-lucky%C3%A2-%C3%A2-%C3%A2-successful-management-of-an-acute-endobronchial-tumour-embolism-in-the-icu-a-case-report-and-review-of-the-literature
#2
Christopher J Walsh, Ron Olivenstein, Eric Forget, Anne V Gonzalez
Endobronchial tumour embolism is a rare cause of acute central airway obstruction. It is primarily reported during pneumonectomy, and the outcome is frequently fatal. Successful management requires the urgent removal of tumour with rigid or flexible bronchoscopy. We present the case of a 62-year-old woman with poorly differentiated non-small cell lung cancer (NSCLC), referred to our institution for Nd:YAG laser photoresection of endobronchial tumour completely obstructing the right mainstem bronchus (RMSB)...
May 2017: Respirology Case Reports
https://www.readbyqxmd.com/read/28212154/optical-coherence-tomography-and-confocal-laser-endomicroscopy-in-pulmonary-diseases
#3
Lizzy Wijmans, Julia N S d'Hooghe, Peter I Bonta, Jouke T Annema
PURPOSE OF REVIEW: Current imaging techniques (X-ray, computed tomography scan, ultrasound) have limitations in the identification and quantification of pulmonary diseases, in particular, on highly detailed level. The purpose of this review is to provide an overview of the current knowledge of innovative light- and laser-based imaging techniques that might fill this gap. RECENT FINDINGS: Optical coherence tomography (OCT) and confocal laser endomicroscopy (CLE) are high-resolution imaging techniques, which, combined with bronchoscopy, provide 'near histology' detailed imaging of the airway wall, lung parenchyma, mediastinal lymph nodes, and pulmonary vasculature...
February 16, 2017: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/28197412/bronchoscopic-diagnosis-and-treatment-of-primary-tracheobronchial-amyloidosis-a-retrospective-analysis-from-china
#4
Xiaoxiao Lu, Bixiu He, Ge Wang, Baimei He, Lijing Wang, Qiong Chen
Objective. To assess the value of bronchoscopy in the diagnosis and treatment of primary tracheobronchial amyloidosis (TBA), in order to reduce misdiagnosis rates and improve prognosis. Methods. Clinical data of 107 patients with TBA reported from 1981 to 2015 in China were retrospectively analyzed for clinical features, bronchoscopic manifestations, pathologies, treatments, and outcomes. Results. 105 of 107 TBA patients were pathologically confirmed by bronchoscopy. Main bronchoscopic manifestations of TBA were single or multiple nodules and masses within tracheobronchial lumens; local or diffuse luminal stenosis and obstruction; luminal wall thickening and rigidity; rough or uneven inner luminal walls; congestion and edema of mucosa, which was friable and prone to bleeding upon touch; and so forth...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28123486/comparison-of-the-efficacy-of-four-endobronchial-ablation-techniques-in-dogs
#5
Linrong Tong, Koudong Zhang, Haidong Huang, Wei Zhang, Xingxing Zhang, Qin Wang, Qiang Li, Chong Bai
The present study aimed to evaluate the safety and efficacy of four commonly used ablation techniques, namely neodymium-doped yttrium aluminium garnet (Nd:YAG) laser therapy, argon plasma coagulation (APC), high-frequency electrocautery and CO2 cryotherapy. The techniques were performed at various powers or impedance settings, and for various durations, on the trachea of beagle dogs. Pathological changes of the tracheal wall were assessed by bronchoscopy. The endoscopic gross appearance of lesions induced by ablation treatments was consistent with the histopathological changes...
January 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28100359/-holmium-yttrium-aluminum-garnet-ho-yag-laser-lithotripsy-in-the-treatment-of-broncholithiasis
#6
Y Cheng, W Zhang, H Zhang, Y Liu, N Li, J Cao, G F Wang
Objective: To assess the effectiveness of Ho: YAG Laser in the treatment of broncholithiasis. Methods: We retrospectively reviewed the clinical data of 6 patients who underwent Ho: YAG Laser lithotripsy in Peking University First Hospital during May 2012 to October 2015. 4 females and 2 males, with a median age of 60 years, were enrolled. Among 6 patients, persistent cough(n=2), hemoptysis(n=2), recurrent pneumonia(n=2) were the main clinical symptoms. Broncholiths were found in the left side in 1 patient and right side in 5 patients...
January 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28066614/the-role-of-bronchoscopy-in-the-diagnosis-of-early-lung-cancer-a-review
#7
REVIEW
Marco Andolfi, Rossella Potenza, Rosanna Capozzi, Valeria Liparulo, Francesco Puma, Kazuhiro Yasufuku
Lung cancer is the leading cause of cancer-related deaths worldwide with an overall 5-year survival rate of 17% after diagnoses. Indeed many patients tend to have a very poor prognosis, due to being diagnosed at an advanced stage. Conversely patients who are diagnosed at an early stage have a 5-year survival >70%, indicating that early detection of lung cancer is crucial to improve survival. Although flexible bronchoscopy is a relatively non-invasive procedure for patients suspected of having lung cancer, only 29% of carcinoma in situ (CIS) and 69% of microinvasive tumors were detectable using white light bronchoscopy (WLB) alone...
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27867576/resection-with-preserved-histologic-morphology-of-a-rare-tumour-via-bronchoscopic-cryosurgery
#8
Jessica Han Ying Tan, Angela Maria Takano, Anne Ann Ling Hsu
Tracheobronchial leiomyoma is a rare pulmonary neoplasm accounting for <2% of benign tumours of the lower airway. Published case series reported bronchoscopic resectability with laser ablation for lesions located in the large airway. Surgery was performed for tumours with wide-based and tumours located in segmental bronchus or lung parenchyma. This is the first reported case of complete bronchoscopic cryoresection of leiomyoma arising from the subsegmental bronchi and illustrating the cryopreservation of its histologic morphology...
October 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27792269/impaired-immunosuppressive-effect-of-bronchoalveolar-mesenchymal-stem-cells-in-hypersensitivity-pneumonitis-preliminary-findings
#9
Enikő Balogh, Béla Nagy, Ágnes Gyetvai, Zsolt Bene, Zoltán Hendrik, Viktória Jeney, Péter Nagy, Ágnes Papp, József Balla, György Balla, János Kappelmayer, Béla Nagy
BACKGROUND: Bronchoalveolar mesenchymal stem cells (MSCs) play an important role in the maintenance of lung integrity. Therapeutic application of bone marrow-derived MSCs reduced chronic bronchial inflammation in idiopathic pulmonary fibrosis, and improved the ratio of survivors in sepsis with pneumonia. This study investigated the effect of MSCs from bronchoalveolar lavage fluid (BALF) of hypersensitivity pneumonitis (HP) on T-cell function under in vitro conditions. METHODS: Bronchoalveolar MSCs were obtained via bronchoscopy with BAL from children with severe subacute HP...
October 28, 2016: Cytometry. Part B, Clinical Cytometry
https://www.readbyqxmd.com/read/27594885/tracheobronchial-amyloidosis-mimicking-tracheal-tumor
#10
Elif Tanrıverdi, Mehmet Akif Özgül, Oğuz Uzun, Şule Gül, Mustafa Çörtük, Zehra Yaşar, Murat Acat, Naciye Arda, Erdoğan Çetinkaya
Tracheobronchial amyloidosis is a rare presentation and accounts for about 1% of benign tumors in this area. The diagnosis of disease is delayed due to nonspecific pulmonary symptoms. Therapeutic approaches are required to control progressive pulmonary symptoms for most of the patients. Herein, we report a case of a 68-year-old man admitted with progressive dyspnea to our institution for further evaluation and management. He was initially diagnosed with and underwent management for bronchial asthma for two years but had persistent symptoms despite optimal medical therapy...
2016: Case Reports in Medicine
https://www.readbyqxmd.com/read/27493804/high-dose-rate-brachytherapy-as-a-treatment-option-in-endobronchial-tumors
#11
Ali Hosni, Andrea Bezjak, Alexandra Rink, Kasia Czarnecka, Andrew McPartlin, Susan Patterson, Elantholiparameswaran Saibishkumar
Purpose. To report our experience with high dose rate endobronchial brachytherapy (HDR-EBBT) and to assess its efficacy and tolerability with possibility of its use in selected cases with curative intent. Method. Retrospective review of patients with endobronchial tumors treated at our institution in 2007-2013 with HDR-EBBT. Subjective response and treatment related toxicity were extracted from patients' records. Clinical response was evaluated by chest CT +/- bronchoscopy 2-3 months after treatment. Local control (LC) and overall survival (OS) were analyzed...
2016: Lung Cancer International
https://www.readbyqxmd.com/read/27487178/the-molecular-bronchoscope-a-tool-for-measurement-of-spatially-dependent-co2-concentrations-in-the-lungs
#12
Luca Ciaffoni, John H Couper, Graham Richmond, Gus Hancock, Grant A D Ritchie
Respiratory physicians use bronchoscopy for visual assessment of the lungs' topography and collecting tissue samples for external analysis. We propose a novel bronchoscope tool that would enable spatially dependent measurements of the functioning of the lungs by determining local concentrations of carbon dioxide, which will be produced by healthy parts of the lung at rates that are higher than from portions where gas exchange is impaired. The gas analyzer is based on a compact laser absorption spectrometer making use of fiber optics for delivery and return of low intensity diode laser radiation to and from the measurement chamber at the distal end of a flexible conduit...
September 6, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/27446391/endobronchial-fibroma-in-a-pneumoconiosis-patient-with-a-history-of-tuberculosis-a-case-report-and-literature-review
#13
Meifang Wang, Yuquan Liu, Dan Li, Chang Xiong, Xin Qian, Yijun Tang
Bronchial fibroma is uncommon, with only 18 cases reported since 1948. The current study presents a rare case of endobronchial fibroma, along with a relevant literature review. A 54-year-old male patient with pneumoconiosis and a history of tuberculosis was admitted to the Taihe Hospital Affiliated With Hubei University of Medicine, Shiyan, China, due to refractory dry cough. Computed tomography of the chest showed multiple nodular and confluent opacities in the lung and one cavitation in the right upper lobe region...
August 2016: Oncology Letters
https://www.readbyqxmd.com/read/27440036/-photodynamic-therapy-for-lung-cancer
#14
Keishi Ohtani, Norihiko Ikeda
In Japan, Photodynamic therapy (PDT) is recommended as a treatment option for centrally located early-stage lung cancers (CLELCs). It is a minimally invasive treatment with excellent anti-tumor effects. The 2nd generation photosensitizer, talaporfin sodium has strong anti-tumor effects with much less photosensitivity than porfimer sodium. Moreover, the laser equipment is compact and portable, and talaporfin sodium is now the current mainstay of PDT for lung cancer. For successful PDT, accurate evaluation of tumor extent and bronchial invasion is crucial...
July 2016: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/27362271/usefulness-of-bronchoscopic-probe-based-confocal-laser-endomicroscopy-in-the-diagnosis-of-pneumocystis-jirovecii-pneumonia
#15
Hanaa Shafiek, Federico Fiorentino, Borja G Cosio, Ana Kersul, Luc Thiberville, Cristina Gómez, Melchor Riera, Maria L Martín, Rocio Martínez, Maria A Noguera, Alvar Agustí, Jaume Sauleda
BACKGROUND: Probe-based confocal laser endomicroscopy (pCLE) is a novel technique that provides in vivo microscopic imaging of the distal lung. We hypothesized that the intra-alveolar exudates characterizing Pneumocystis jirovecii pneumonia (PJP) can be identified by pCLE in vivo and help in its diagnosis. OBJECTIVES: We aimed to assess the usefulness of pCLE for the in vivo diagnosis of PJP. METHODS: Thirty-two human immunodeficiency virus (HIV)-positive patients with new pulmonary infiltrates and fever were studied using pCLE...
2016: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/27290957/air-q-laryngeal-airway-for-rescue-and-tracheal-intubation
#16
Ayman Ads, Frederic Auerbach, Kelly Ryan, Abdel R El-Ganzouri
We report the successful use of the Air-Q laryngeal airway (Air-Q LA) as a ventilatory device and a conduit for tracheal intubation to rescue the airway in a patient with difficult airway and tracheal stenosis. This is the first case report of the device to secure the airway after two episodes of hypoxemia in the operating room and intensive care unit. Consent for submission of this case report was obtained from our institution's human studies institutional review board given that the patient died a few months after his discharge from the hospital before his personal consent could be obtained and before preparation of this report...
August 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27022925/respiratory-conditions-associated-with-tracheobronchomegaly-mounier-kuhn-syndrome-a-study-of-seventeen-cases
#17
Pierre Schmitt, Levent Dalar, Stéphane Jouneau, Bénédicte Toublanc, Juliette Camuset, Gérard Chatte, Laurent Cellerin, Hervé Dutau, Stéphane Sanchez, Maxime Sauvage, Jean-Michel Vergnon, Sandra Dury, Gaetan Deslée, François Lebargy
BACKGROUND: Mounier-Kuhn syndrome (MKS) is a rare disorder characterized by enlargement of the trachea and main bronchi and associated with recurrent respiratory tract infections. OBJECTIVE: This multicenter, retrospective study was carried out to describe respiratory conditions associated with tracheobronchomegaly. METHODS: Nine institutions involved in the 'Groupe d'Endoscopie de Langue Française' (GELF) participated in this study. A standard form was used to record patient characteristics, treatments and follow-up from medical charts...
2016: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/27006182/a-new-endoscopic-hand-drill-for-management-of-tracheal-stenosis
#18
Sandro Batzella, Gabriele Lucantoni, Alfonso Fiorelli, Raffaele Dello Iacono, Paolo Battistoni, Umberto Caterino, Mario Santini, Giovanni Galluccio
Tracheal resection and primary anastomosis is the treatment of choice for the management of benign tracheal stenoses. Rigid endoscopy with laser-assisted mechanical dilatation is an alternative to surgery and helps to improve symptoms and quality of life in patients unfit for surgery. Here, we describe the treatment of a simple web-like stenosis, using a new endoscopic hand drill that was assembled by sharpening the blunt tip of a standard endoscopic cotton applicator. The bronchoscopy was positioned proximally to the stenotic lesion and radial holes were made at 12, 3 and 9 o'clock...
July 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/26286177/the-tools-of-the-trade-uses-of-flexible-bronchoscopy
#19
REVIEW
Varinder Singh, Kamal Kumar Singhal
Bronchoscopes have markedly improved the diagnosis as well as therapy in pediatric pulmonary disorders. Two types of bronchoscopes are available; flexible and rigid, with their own advantages and disadvantages. Depending on the clinical need and availability of skills, choice is made between the two. Typically, rigid scopes are largely used by the surgeons (pediatric or otolayngologists) while flexible bronchoscope stays in the domain of the pediatric pulmonologist and intensivists. Rigid scopes may be more versatile than flexible bronchoscopes in removing the foreign bodies from the airway...
October 2015: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/26216723/a-novel-method-for-in-vivo-imaging-of-solitary-lung-nodules-using-navigational-bronchoscopy-and-confocal-laser-microendoscopy
#20
T Hassan, N Piton, S Lachkar, M Salaün, L Thiberville
Solitary pulmonary nodules (SPN) have become increasingly prevalent and diagnostic management remains challenging. We demonstrate a novel technique in which probe-based confocal endomicroscopy (pCLE) could be performed to microimage SPN in vivo and in real-time. Two confocal wavelengths (488 and 660 nm with methylene blue (MB)) were used for elastin network and cellular imaging, respectively using pCLE in conjunction with r-EBUS and virtual navigation. In the first case, the 1-mm Alveoflex was used to image a metastatic melanoma in a subcentimetric nodule in the right middle lobe...
October 2015: Lung
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