keyword
https://read.qxmd.com/read/38529773/increased-risk-of-complications-in-lower-versus-upper-limb-peripheral-intravenous-cannulation-in-children-with-severe-neurological-impairment
#1
JOURNAL ARTICLE
Eliza Kluckow, Sajini Perera, Isaac Clifford, Daniel Wilks, Monica S Cooper
BACKGROUND: Obtaining peripheral intravenous catheter (PIVC) access in children with severe neurological impairment (SNI) is often challenging and commonly associated with complications, including dislodgement, phlebitis and extravasation. In severe cases, extravasation injury may lead to tissue necrosis, ulceration and long-term morbidity. The aim of this study was to determine the relative incidence of PIVC complications secondary to lower limb cannulation, compared to upper limb, in children with SNI...
March 2024: Child: Care, Health and Development
https://read.qxmd.com/read/38513798/obese-patients-with-ceap-c2-and-c3-disease-show-enhanced-symptom-improvement-after-endovenous-thermal-ablation
#2
JOURNAL ARTICLE
Zachary R Zottola, Joshua T Geiger, Geena E Choo, Baqir J Kedwai, Mark D Balceniuk, Jennifer L Ellis, Adam J Doyle, Karina A Newhall
OBJECTIVE: Endovenous thermal ablation (EVTA) is a prevalent treatment option in patients with severe venous disease. However, the decision to intervene on patients with less severe disease (CEAP C2 & C3) is less clear and becomes further complicated in patients suffering from obesity, a pathology known to increase venous disease symptom severity. Therefore, the objective of this study was to use the Society for Vascular Surgery Vascular Quality Initiative (SVS-VQI) database to evaluate outcomes following EVTA in obese patients with CEAP C2 and C3 venous insufficiency...
March 19, 2024: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://read.qxmd.com/read/38512390/trends-in-the-prevalence-and-risk-factors-for-peripherally-inserted-central-catheter-related-complications-in-cancer-patients-from-2016-to-2022-a-multicenter-study
#3
JOURNAL ARTICLE
Shengxiao Nie, Lei Wang, Shengmiao Ma, Hong Sun
PURPOSE: To identify the trends in the prevalence of peripherally inserted central catheter (PICC) related complications in cancer patients and explore the risk factors for complications and occurrence speed. METHODS: A total of 3573 cancer patients with PICC were recruited at 17 hospitals from 2016 to 2022. Logistic and COX regression were performed to identify influencing factors of PICC-related complications and incidence speed, respectively. RESULTS: The proportion of symptomatic PICC-related thrombosis, phlebitis, and infections reported had decreased from 59...
March 21, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38510884/a-multicentric-prospective-observational-single-arm-registry-study-to-assess-the-clinical-safety-and-effectiveness-of-thrombophob-ointment-heparin-sodium-benzyl-nicotinate-in-indian-patients-with-thrombophlebitis
#4
JOURNAL ARTICLE
Harsha Somavarapu, Kumar Kamala Kant Rakesh, Gyan Roy, Vinod Kumar Navkar, Nimitha Pinto, Sameer Muchhala, Pavankumar M Daultani, Ravindra Mittal
Purpose Thrombophlebitis is a frequent intravenous (IV) therapy consequence. Topical heparin for seven days is used as a treatment for thrombophlebitis. This study was performed to evaluate the clinical safety and effectiveness of the combination of heparin sodium & benzyl nicotinate (Thrombophob Ointment, manufactured by Zydus Healthcare Ltd., Ahmedabad, India) in thrombophlebitis patients in India. Methods A study carried out by 118 Indian doctors examined 2002 thrombophlebitis patients from 2016-2023, prescribing ointment containing heparin sodium and benzyl nicotinate...
February 2024: Curēus
https://read.qxmd.com/read/38490927/port-a-randomized-cross-over-phase-2-study-of-melflufen-peripheral-versus-central-intravenous-administration-in-patients-with-relapsed-refractory-multiple-myeloma
#5
JOURNAL ARTICLE
Ludek Pour, Ilina Micheva, Ganna Usenko, Gabor Mikala, Tamas Masszi, Kameliya Simeonova, Marcus Thuresson, Gunilla Huledal, Stefan Norin, Nicolaas A Bakker, Jiri Minarik
BACKGROUND: Melflufen, a first-in-class alkylating peptide-drug conjugate, rapidly enters tumor cells and metabolizes to melphalan. In previous studies, melflufen was administered via central venous catheter (CVC). However, administration by peripheral venous catheter (PVC) may be preferable. PATIENTS AND METHODS: PORT was a two-period, phase 2 crossover study of CVC versus PVC melflufen administration in patients with relapsed/refractory multiple myeloma. Adults with ≥ 2 prior therapies refractory to/intolerant of an immunomodulatory drug and a proteasome inhibitor were randomized 1:1 to weekly oral dexamethasone plus melflufen (40 mg) via CVC or PVC infusion on day 1 of 28-day cycle 1...
February 23, 2024: Clinical Lymphoma, Myeloma & Leukemia
https://read.qxmd.com/read/38490874/exploring-clinicians-insertion-experience-with-a-new-peripheral-intravenous-catheter-in-the-emergency-department
#6
JOURNAL ARTICLE
Hui Grace Xu, Areum Hyun, Evelyn Kang, Nicole Marsh, Amanda Corley
BACKGROUND: Hospitals frequently introduce new medical devices. However, the process of clinicians adapting to these new vascular access devices has not been well explored. The study aims to explore clinicians' experience with the insertion of a new guidewire peripheral intravenous catheter (PIVC) introduced in the emergency department (ED) setting. METHODS: The study was conducted at two EDs in Queensland, Australia, utilising a qualitative explorative approach...
March 14, 2024: Australasian emergency care
https://read.qxmd.com/read/38471637/retrospective-analysis-of-factors-associated-with-umbilical-diseases-in-foals
#7
JOURNAL ARTICLE
F Perina, J Mariella, N Ellero, F Freccero, C Castagnetti, A Lanci
In neonatal foals, umbilical remnants can be affected by infectious and non-infectious diseases. This study aimed to retrospectively evaluate historical, management and clinical factors that may be related to the occurrence of umbilical remnant diseases. Clinical reports of foals born or hospitalized within 24h of life during the 2017-2021 foaling seasons were reviewed. Forty/183 foals (21.9%) developed umbilical remnant diseases (URD group), while 143/183 foals (78.1%) had normal umbilical remnants (NUR group)...
March 10, 2024: Journal of Equine Veterinary Science
https://read.qxmd.com/read/38457231/mannitol-versus-furosemide-in-patients-with-thoracic-malignancies-who-received-cisplatin-based-chemotherapy-using-short-hydration-a-randomized-phase-ii-trial
#8
JOURNAL ARTICLE
Eriko Murakami, Hiroaki Akamatsu, Shunsuke Teraoka, Toshiaki Takakura, Eri Takase, Masanori Tanaka, Takahiro Kaki, Yuhei Harutani, Katsuyuki Furuta, Takeya Sugimoto, Ryota Shibaki, Daichi Fujimoto, Atsushi Hayata, Yuichi Ozawa, Masanori Nakanishi, Yasuhiro Koh, Toshio Shimokawa, Nobuyuki Yamamoto
BACKGROUND: Mannitol is exclusively recommended in the National Comprehensive Cancer Network guidelines for diuresis in cisplatin (CDDP)-based chemotherapy. The utility of furosemide, a widely used and convenient diuretic, thus requires clarification. METHODS: This is a prospective, single-centered, open-label, noninferiority phase II study. Patients with thoracic malignancies who planned to receive CDDP-based chemotherapy were randomly assigned to receive either mannitol (arm A) or furosemide (arm B)...
February 2024: Cancer Medicine
https://read.qxmd.com/read/38437947/-women-s-experience-following-prophylactic-low-molecular-weight-heparin-treatment-post-cesarean-section
#9
JOURNAL ARTICLE
Philippe Deruelle, Camille Debalme, Karine Garcia-Lebailly, Carole Di Giusto, Loïc Sentilhes
OBJECTIVE: To assess women's experiences with skin-related side effects following subcutaneous Low Molecular Weight Heparin (LMWH) injections after a cesarean section, and to analyze their impact on treatment adherence. METHOD: A questionnaire was developed in collaboration with Cesarine, a patients' association, to explore various aspects of LMWH administration, including prevention methods, cutaneous side effects, treatment compliance, perceived constraints, apprehension, and understanding of treatment benefits...
March 2, 2024: Gynecologie, Obstetrique, Fertilite & Senologie
https://read.qxmd.com/read/38428500/risk-factors-for-recanalization-of-truncal-veins-following-endoluminal-ablation
#10
JOURNAL ARTICLE
Matthew Vuoncino, Joel Harding, Nasim Hedayati, Mimmie Kwong
BACKGROUND: Recanalization of target veins following treatment of superficial venous incompetence has clinical implications and may be dependent on the type of intervention. The aim of this study was to evaluate patient and procedural factors associated with truncal vein recanalization in a large study cohort using the Vascular Quality Initiative (VQI) Varicose Vein Registry. METHODS: We performed a retrospective review using the VQI Varicose Vein Registry from 2014 to 2018...
February 28, 2024: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://read.qxmd.com/read/38422406/phlebitis-in-medical-surgical-units-a-case-control-study-in-a-brazilian-hospital
#11
JOURNAL ARTICLE
Isabela Granado Antequera, Amanda Saba, Maryana da Silva Furlan
The most commonly used vascular access is the peripheral intravenous catheter (PIVC). However, it can trigger complications and the occurrence of adverse events, such as phlebitis. This study evaluated the variables that are associated with the occurrence of phlebitis in medical and surgical inpatient units. This is an observational, retrospective, case-control study in medical and surgical hospitalization units of a private general hospital in the city of São Paulo. Participants were an average age of 66...
March 2024: Journal of Infusion Nursing: the Official Publication of the Infusion Nurses Society
https://read.qxmd.com/read/38422405/the-prevalence-and-associated-factors-of-peripheral-intravenous-complications-in-a-thai-hospital
#12
JOURNAL ARTICLE
Kraiwan Kaphan, Siriporn Auypornsakul, Jenjira Somno, Watsaporn Wongwattananan, Kamonthip Jamsittikul, Wilaiporn Baicha, Saowanuch Somsri, Thanyanan Sawatrak
Complications of peripheral intravenous catheters (PIVCs) remain a major contributor to health care costs and are a patient safety problem. The objective of this cross-sectional descriptive study was to examine the prevalence of complications and factors associated with complications from peripheral intravenous fluid administration. The study was conducted at a tertiary care hospital in Thailand. The instruments were developed from the literature review. Data were analyzed using SPSS statistics, version 22...
March 2024: Journal of Infusion Nursing: the Official Publication of the Infusion Nurses Society
https://read.qxmd.com/read/38382993/comparison-of-the-physicochemical-properties-of-branded-and-generic-glucose-added-maintenance-hypotonic-infusion-fluids-to-assess-the-potential-for-phlebitis-and-incompatibility-with-other-drugs
#13
JOURNAL ARTICLE
Sawako Takei, Soh Katsuyama, Yusuke Hori
In Japan, the switch from branded to generic infusion fluids has been promoted as a national policy. Recently, as generic products have been in short supply, the switch from generic to branded infusion fluids has increased. However, certain additives for injectable infusion fluids, such as nonvolatile acids like acetic acid and hydrochloric acid, are not required to be listed in the package insert. We hypothesized that the addition of nonvolatile acids may be one of the reasons for the differences in physicochemical properties between the branded and generic infusion fluids...
February 21, 2024: Drug Discoveries & Therapeutics
https://read.qxmd.com/read/38378635/single-cell-rna-sequencing-of-submandibular-gland-reveals-collagen-type-xv-positive-fibroblasts-as-a-disease-characterizing-cell-population-of-igg4-related-disease
#14
JOURNAL ARTICLE
Shigeru Tanaka, Takuya Yamamoto, Arifumi Iwata, Masahiro Kiuchi, Kota Kokubo, Tomohisa Iinuma, Takahiro Sugiyama, Toyoyuki Hanazawa, Kiyoshi Hirahara, Kei Ikeda, Hiroshi Nakajima
OBJECTIVES: IgG4-related disease (IgG4-RD) is a systemic autoimmune disease with an unknown etiology, affecting single/multiple organ(s). Pathological findings include the infiltration of IgG4-producing plasma cells, obliterative phlebitis, and storiform fibrosis. Although immunological studies have shed light on the dysregulation of lymphocytes in IgG4-RD pathogenesis, the role of non-immune cells remains unclear. This study aimed to investigate the demographics and characteristics of non-immune cells in IgG4-RD and explore potential biomarkers derived from non-immune cells in the sera...
February 20, 2024: Arthritis Research & Therapy
https://read.qxmd.com/read/38375285/immunoglobulin-g4-related-thyroiditis-associated-with-graves-disease-a-case-report
#15
Hiroyuki Takahashi, Sabine Kajita, Hiroshi Katoh, Toshihide Matsumoto, Akemi Inoue, Takafumi Sangai, Makoto Saegusa
We report a case of immunoglobulin (ig)-g4-related thyroiditis associated with graves' disease. a 45-year-old man was diagnosed with graves' disease due to asymptomatic enlarged thyroid gland and high serum levels of thyrotropin receptor antibodies and thyroid hormones. surgical resection of the thyroid gland was performed because of further thyroid gland enlargement and severe fluctuations in the thyroid hormonal levels, despite medical therapy with a combination of an antithyroid drug and a thyroid hormone preparation...
February 29, 2024: Heliyon
https://read.qxmd.com/read/38366675/evaluation-of-the-effect-of-proximal-massage-and-palm-fisting-in-reducing-the-risk-of-peripheral-venous-catheter-related-phlebitis-randomized-control-study
#16
JOURNAL ARTICLE
Betul Tosun, Serap Gungor, Esengül Agkale, Senem Andi
AIM: Peripheral venous catheter is a clinical procedure often performed by nurses in hospitals. Phlebitis can be prevented with more nursing care by applying peripheral venous catheter by trained nurses and using preventive methods. The aim of this study was to investigate the effect of proximal massage and palm fisting on the prevention of phlebitis in patients with a peripheral venous catheter (PVC). METHODS AND RESULTS: This randomized controlled study was conducted with patients who were hospitalized in the orthopedics and traumatology service of a state hospital and had PVC...
February 16, 2024: European Journal of Cardiovascular Nursing
https://read.qxmd.com/read/38363545/safety-of-intravenous-push-valproate-compared-with-intravenous-piggyback-at-a-tertiary-academic-medical-center
#17
JOURNAL ARTICLE
Felicia Y Wang, Kevin C McLaughlin, Michael J Schontz, Jeremy R DeGrado, Robert E Dannemiller
BACKGROUND AND OBJECTIVES: Data are limited regarding the safety associated with administering valproate sodium by intravenous push (IVP) compared with intravenous piggyback (IVPB). The objective of this retrospective pre-post analysis was to compare the safety profile of valproate administration via IVPB from March to May 2022 and IVP from June to August 2022. METHODS: A total of 890 IVPB and 440 IVP administrations were included. The major endpoint of this analysis was the incidence of infusion site reactions (infiltration or phlebitis)...
February 16, 2024: Clinical Drug Investigation
https://read.qxmd.com/read/38349655/safety-and-efficacy-of-midline-vs-peripherally-inserted-central-catheters-among-adults-receiving-iv-therapy-a-randomized-clinical-trial
#18
RANDOMIZED CONTROLLED TRIAL
Simon L Thomsen, Rikke Boa, Lars Vinter-Jensen, Bodil S Rasmussen
IMPORTANCE: Midline catheters (MCs) are widely used, but safety and efficacy compared with peripherally inserted central catheters (PICCs) has not been adequately evaluated. OBJECTIVE: To compare the safety and efficacy of MCs with PICCs among adult patients with an anticipated intravenous therapy lasting from 5 to 28 days. DESIGN, SETTING, AND PARTICIPANTS: This parallel, 2-group, open-label, randomized clinical trial (RCT) was conducted in Denmark from October 2018 to February 2022 at a single academic tertiary care center...
February 5, 2024: JAMA Network Open
https://read.qxmd.com/read/38338263/assessment-treatment-and-follow-up-of-phlebitis-related-to-peripheral-venous-catheterisation-a-delphi-study-in-spain
#19
JOURNAL ARTICLE
Alba Torné-Ruiz, Mercedes Reguant, Montserrat Sanromà-Ortiz, Marta Piriz, Judith Roca, Judith García-Expósito
BACKGROUND: Phlebitis related to peripheral venous catheters (PVCs) is a common complication in patients who require these devices and can have important consequences for the patients and the healthcare system. The management and control of the PVC-associated complications is related to nursing competency. The present study aims to determine, at the national level in Spain, the consensus on the assessment, treatment, and follow-up of PVC-related phlebitis and the importance of the actions taken...
February 1, 2024: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/38336606/association-between-peripheral-intravenous-catheters-and-clinical-characteristics-in-the-development-of-phlebitis
#20
JOURNAL ARTICLE
Gonca Ertaş Akyüz, Nuray Turan
BACKGROUND: Serious complications can develop from erroneous insertion of a peripheral intravenous catheter (PIVC). Successful PIVC insertion has a great place in the continuation of IV treatment without causing complications that may require the removal of the PIVC. METHODS: The population for this prospective observational study included patients who had undergone PIVC insertion in the surgical, intensive care, and inpatient units of a large teaching and research hospital in Istanbul...
February 9, 2024: Journal of Vascular Access
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