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https://www.readbyqxmd.com/read/28534729/self-selection-of-frequency-tables-with-bilateral-mismatches-in-an-acoustic-simulation-of-a-cochlear-implant
#1
Matthew B Fitzgerald, Ksenia Prosolovich, Chin-Tuan Tan, E Katelyn Glassman, Mario A Svirsky
BACKGROUND: Many recipients of bilateral cochlear implants (CIs) may have differences in electrode insertion depth. Previous reports indicate that when a bilateral mismatch is imposed, performance on tests of speech understanding or sound localization becomes worse. If recipients of bilateral CIs cannot adjust to a difference in insertion depth, adjustments to the frequency table may be necessary to maximize bilateral performance. PURPOSE: The purpose of this study was to examine the feasibility of using real-time manipulations of the frequency table to offset any decrements in performance resulting from a bilateral mismatch...
May 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28532056/stiff-porous-scaffolds-from-magnetized-alumina-particles-aligned-by-magnetic-freeze-casting
#2
Michael B Frank, Steven E Naleway, Tsuk Haroush, Chin-Hung Liu, Sze Hei Siu, Jerry Ng, Ivan Torres, Ali Ismail, Keyur Karandikar, Michael M Porter, Olivia A Graeve, Joanna McKittrick
Bone consists of a hard mineral phase and a compliant biopolymer phase resulting in a composite material that is both lightweight and strong. Osteoporosis that degrades spongy bone preferentially over time leads to bone brittleness in the elderly. A porous ceramic material that can mimic spongy bone for a one-time implant provides a potential solution for the future needs of an aging population. Scaffolds made by magnetic freeze casting resemble the aligned porosity of spongy bone. A magnetic field applied throughout freezing induces particle chaining and alignment of lamellae structures between growing ice crystals...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28520540/virtual-surgery-for-conduit-reconstruction-of-the-right-ventricular-outflow-tract
#3
Chin Siang Ong, Yue-Hin Loke, Justin Opfermann, Laura Olivieri, Luca Vricella, Axel Krieger, Narutoshi Hibino
PURPOSE: Virtual surgery involves the planning and simulation of surgical reconstruction using three-dimensional (3D) modeling based upon individual patient data, augmented by simulation of planned surgical alterations including implantation of devices or grafts. Here we describe a case in which virtual cardiac surgery aided us in determining the optimal conduit size to use for the reconstruction of the right ventricular outflow tract. DESCRIPTION: The patient is a young adolescent male with a history of tetralogy of Fallot with pulmonary atresia, requiring right ventricle-to-pulmonary artery (RV-PA) conduit replacement...
May 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28500496/patient-specific-instrumentation-improves-alignment-of-lateral-unicompartmental-knee-replacements-by-novice-surgeons
#4
Chin Ting Justin Ng, Simon Newman, Simon Harris, Susannah Clarke, Justin Cobb
PURPOSE: Patient-specific instrumentation (PSI) has the potential to offer numerous benefits-not least of all, improved resection accuracy; but its potential has not been realised in clinical studies. An explanation may be the focus of such studies on the total knee replacement (TKR-a common procedure, with which surgeons are generally very familiar. Consequently, we sought to investigate the potential role of PSI in guiding novice surgeons to perform the more technically demanding and less familiar lateral unicondylar knee replacement (LUKR)...
May 13, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28486019/role-of-bone-marrow-mononuclear-cell-seeding-for-nanofiber-vascular-grafts
#5
Takuma Fukunishi, Cameron A Best, Chin Siang Ong, Tyler Groehl, James Reinhardt, Tai Yi, Hideki Miyachi, Huaitao Zhang, Toshiharu Shinoka, Christopher K Breuer, Jed Johnson, Narutoshi Hibino
OBJECTIVE: Electrospinning is a promising technology that provides biodegradable nanofiber scaffolds for cardiovascular tissue engineering. However, success with these materials has been limited, and the optimal combination of scaffold parameters for a tissue-engineered vascular graft (TEVG) remains elusive. The purpose of the present study is to evaluate the effect of bone marrow mononuclear cell (BM-MNC) seeding in electrospun scaffolds to support the rational design of optimized TEVGs...
May 9, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28437352/effect-and-strategy-of-1-stage-interrupted-2-level-transpedicular-wedge-osteotomy-for-correcting-severe-kyphotic-deformities-in-ankylosing-spondylitis
#6
Yongfei Zhao, Yan Wang, Zheng Wang, Xuesong Zhang, Keya Mao, Yonggang Zhang
STUDY DESIGN: Prospective study. OBJECTIVE: To investigate the safety, outcome, and strategy of the 1-stage interrupted 2-level transpedicular wedge osteotomy for correcting the severe kyphotic deformity in ankylosing spondylitis (AS). SUMMARY OF BACKGROUND DATA: There has been a large series in the literature reporting on results of osteotomy for the correction of kyphotic deformity secondary to AS. However, few articles have reported, in detail, the plan, design, strategy, and effect of 1-stage interrupted 2-level transpedicular wedge osteotomy for the correction of severe kyphotic deformity in AS...
May 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28412801/-preliminary-report-on-the-application-of-femtosecond-laser-assisted-anterior-capsulotomy-in-intumescent-white-cataract-surgery
#7
T T Peng, Y Wang, X Y Bao
Objective: To assess the effect of femtosecond laser-assisted anterior capsulotomy in intumescent white cataract surgery. Methods: Retrospective case series study. One hundred and fifty cataract patients (150 eyes) from June 2014 to June 2015 in Wuhan Aier ophthalmology hospital were enrolled in this study. They were divided into three groups: 50 intumescent white cataract patients (50 eyes) in the study group were performed femtosecond laser-assisted capsulotomy (LenSx system) operation selectively. Fifty intumescent white cataract patients (50 eyes) underwent normal manual continuous circular capsulorhexis as the control group 1...
April 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28412800/-visual-quality-comparison-after-multifocal-toric-intraocular-lens-or-monofocal-toric-intraocular-lens-implantation
#8
K Feng, H K Guo, Y L Zhang, Z Wu
Objective: To compare visual quality and satisfaction after multifocal toric intraocular lens (Acrysof IQ Restor toric, ART) and monofocal toric intraocular lens implantation in patients. Methods: It was a prospective nonrandomized Phase Ⅲ clinical trial. Patients with age-related cataract and corneal astigmatism were enrolled and accepted phacoemulsification combined with implantation of intraocular lens (IOL) in Henan Provincial Eye Hospital during March 2013 to December 2014. Fifty-six cases were divided into two groups according to which IOL they chose...
April 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28412799/-long-term-outcomes-after-cataract-surgery-in-infants-with-congenital-cataract
#9
J Y Qi, W Xiao, M Y Wang, D X Zhao, W Pu
Objective: To observe the long-term outcomes after congenital cataract surgery performed prior to 36 months of age. Methods: A retrospective case study was conducted. Thirty-two cases (57 eyes) of congenital cataract were included from January 2004 to January 2012. All patients received intraocular lens (IOL) implantation with posterior continuous curvilinear capsulorhexies and anterior vitrectomy after cataract extraction and were followed up. At the last visit, the best corrected visual acuity (BCVA) was determined and postoperative complications were evaluated during follow-up with a longest time of 13 years...
April 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28412798/-intraocular-lens-power-calculation-for-high-myopic-eyes-with-cataract-comparison-of-three-formulas
#10
X J Zhu, W W He, Y Du, D J Qian, J H Dai, Y Lu
Objective: To compare the accuracy of three different formulas for intraocular lens power calculation in high myopic eyes with cataract and analyze their influencial factors. Methods: One hundred and three high myopic patients of cataract (103 eyes), with average age of 60.2±8.8 years old (39.0-77.0), including 45 male and 54 female and with axial length ≥ 26 mm were enrolled in this retrospective case-series study. All of them underwent routine ocular examination and IOLMastermeasurement preoperatively and then underwent phacoemulsification through temporal clear-corneal incision with implantation of HumanOptic posterior chamber Intraocular lens (IOL)...
April 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28412796/-multiple-issues-in-multifocal-intraocular-lens
#11
Z H Li, Z Ye, Y Huang
The occurrence of multifocal intraocular lens (MIOL) is known as an important period in the development of cataract surgery, which can provide a simultaneous vision without the use of spectacles or contact lenses. However, in the current stage, MIOL implantation may also lead to decreased visual acuity and increased risk of photic phenomena, thus in some instance a second procedure to exchange the MIOL is necessary. Optimizing visual outcomes of MIOL implantation and controlling adverse effects has become the focus for ophthalmologists...
April 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28402354/simultaneous-ridge-augmentation-and-accelerated-molar-uprighting-for-implant-site-development-two-case-reports-with-a-split-mouth-design
#12
Chin-Wei Wang, Michelle Yuching Chou, Rebecca Chen, Todd Rowe, Mohamed Masoud, David M Kim, Giuseppe Intini
Well-coordinated interdisciplinary dental treatments provide the best esthetic, functional, and long-term results for patients. However, the length of such treatment, which may involve orthodontics, ridge augmentation, and dental implants, often deters patients from pursuing them. The two case reports presented here aim to present the advantage of simultaneous orthodontic molar uprighting and ridge augmentation procedures for future implant site development. Selective decortication of the alveolar bone, performed simultaneously with bone grafting, can accelerate the tooth uprighting process and synergistically reduce treatment duration...
May 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28398151/assessing-bone-type-of-implant-recipient-sites-by-stereomicroscopic-observation-of-bone-core-specimens-a-comparison-with-the-assessment-using-dental-radiography
#13
Min-Wen Fu, E-Chin Shen, Earl Fu, Fu-Gong Lin, Tian-You Wang, Hsien-Chung Chiu
BACKGROUND: We aimed to determine if bone quality evaluation of surgically obtained bone core specimens using a stereomicroscope is reliable for determining bone quality at implant recipient sites. METHODS: Bone quality was pre-surgically assessed in 122 edentulous ridges obtained from 62 patients using periapical radiographs and categorized according to the Lekholm and Zarb classification. During surgery, bone specimens were trephined, and bone types were immediately classified using a stereomicroscope...
March 10, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28374431/characteristics-of-intrabony-nerve-canals-in-mandibular-interforaminal-region-by-using-cone-beam-computed-tomography-and-a-recommendation-of-safe-zone-for-implant-and-bone-harvesting
#14
Xiang-Wen Yang, Fei-Fei Zhang, Yi-Han Li, Bin Wei, Yao Gong
BACKGROUND: Cone-beam computed tomography can accurately show anatomic structure of intrabony nerve canals in mandibular interforaminal region. PURPOSE: The aim was to evaluate the characteristics of intrabony nerve canals in mandibular interforaminal region by using cone-beam computed tomography (CBCT) and determine a safe zone for implant and bone harvesting. MATERIALS AND METHODS: Hemimandibles (824) CBCT images were obtained. The length of the anterior loop (AL), the length and diameter of the mandibular incisive canal (MIC) and its spatial distance in various landmarks were measured...
February 3, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28339041/tanshinone-iia-increases-protein-expression-levels-of-perk-atf6-ire1%C3%AE-chop-caspase%C3%A2-3-and-caspase%C3%A2-12-in-pancreatic-cancer-bxpc%C3%A2-3-cell%C3%A2-derived-xenograft-tumors
#15
Tsung-Lang Chiu, Chin Cheng Su
Tanshinone (Tan)-IIA is a derivative of phenanthrenequinone and the main active ingredient isolated from Salviae miltiorrhizae radix (Danshen). Previous studies have demonstrated that Tan‑IIA increased the protein expressions levels of protein kinase RNA‑like endoplasmic reticulum kinase (PERK), activating transcription factor (ATF) 6, caspase‑12 and CCAAT‑enhancer‑binding protein homologous protein (CHOP), to induce endoplasmic reticulum (ER) stress and apoptosis in human pancreatic cancer BxPC‑3 cells...
May 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28338421/harnessing-the-osteogenicity-of-in-vitro-stem-cell-derived-mineralized-extracellular-matrix-as-3d-biotemplate-to-guide-bone-regeneration
#16
Yoke Chin Chai, Johanna Bolander, Ioannis Papantoniou, Jennifer Patterson, Jef Vleugels, Jan Schrooten, Frank P Luyten
Advanced biomaterials that are capable of guiding robust bone regeneration are highly demanded for translational therapy of bone defects or bone augmentation in clinics. One of the strategic approaches is to produce tissue engineering (TE) constructs that mediate bone regeneration by recapitulating the natural bone formation or healing process. In this study, we aimed at producing devitalized mineralized carriers with augmented bone forming capacity via a modified culture protocol (i.e., culture conditions with high calcium and/or phosphate concentrations) that first promotes cell growth and, subsequently, mineralized extracellular matrix (ECM) deposition by human periosteum-derived osteoprogenitor cells (hPDCs) on additive manufactured three-dimensional (3D) porous titanium (Ti)-based scaffolds...
March 24, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28335666/control-of-dental-derived-induced-pluripotent-stem-cells-through-modified-surfaces-for-dental-application
#17
Hyunmin Choi, Kyu-Hyung Park, Ah-Reum Lee, Chin Hee Mun, Yong Dae Shin, Yong-Beom Park, Young-Bum Park
OBJECTIVE: The aim of this study is to investigate the behaviour of iPSc derived from dental stem cells in terms of initial adhesion, differentiation potential on differently surface-treated titanium disc. MATERIALS AND METHODS: iPSc derived from human gingival fibroblasts (hGFs) were established using 4-reprogramming factors transduction with Sendai virus. The hGF-iPSc established in this study exhibited the morphology and growth properties similar to human embryonic stem (ES) cells and expressed pluripotency makers...
March 23, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28320686/characteristics-of-early-versus-late-in-stent-restenosis-in-second-generation-drug-eluting-stents-an-optical-coherence-tomography-study
#18
Lei Song, Gary S Mintz, Dong Yin, Myong Hwa Yamamoto, Chee Yang Chin, Mitsuaki Matsumura, Ajay J Kirtane, Manish A Parikh, Jeffrey W Moses, Ziad A Ali, Richard A Shlofmitz, Akiko Maehara
AIMS: In-stent restenosis (ISR) is an important cause of DES failure and target vessel revascularization. We evaluated differences between early and late-presenting restenosis in second-generation drug-eluting stents (DES) using optical coherence tomography (OCT). METHODS AND RESULTS: Overall, 171 cases of second-generation DES ISR with a follow-up OCT minimum lumen area <3.0mm2 were included; 33.3% of patients (n=57) had early ISR; and 67.7% (n=114) had late ISR (duration from stent implantation >1 year)...
March 21, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28286279/management-of-esophageal-and-pharyngeal-perforation-as-complications-of-anterior-cervical-spine-surgery
#19
Moo Sung Kang, Kyung Hyun Kim, Jeong Yoon Park, Sung Uk Kuh, Dong Kyu Chin, Byung Ho Jin, Keun Su Kim, Yong Eun Cho
OBJECTIVE: To describe our experience in treating esophageal and pharyngeal perforation after anterior cervical spine surgery. METHODS: Six patients with esophageal injury and one patient with pharyngeal injury after anterior cervical spinal surgery, managed at our department between 2000 and 2015, were retrospectively analyzed. RESULTS: During the study period, seven patients (six male and one female; mean age, 45 years) presented with esophageal perforation...
March 9, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28281026/neoatherosclerosis-assessed-with-optical-coherence-tomography-in-restenotic-bare-metal-and-first-and-second-generation-drug-eluting-stents
#20
Lei Song, Gary S Mintz, Dong Yin, Myong Hwa Yamamoto, Chee Yang Chin, Mitsuaki Matsumura, Khady Fall, Ajay J Kirtane, Manish A Parikh, Jeffrey W Moses, Ziad A Ali, Richard A Shlofmitz, Akiko Maehara
Although reported in bare metal stents (BMS) and first-generation drug-eluting stents (DES), little is known about neoatherosclerosis in second-generation DES. We used optical coherence tomography to evaluate neoatherosclerosis among different stent generations. Overall, 274 in-stent restenosis (ISR) lesions (duration from implantation 56.9 ± 47.2 months) in 274 patients were assessed for the presence of neoatherosclerosis. Neoatherosclerosis was identified in 38.7% of lesions (106/274): 23.0% second-generation DES (38/165), 65...
March 9, 2017: International Journal of Cardiovascular Imaging
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