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https://www.readbyqxmd.com/read/27890337/a-double-button-adjustable-loop-device-is-biomechanically-equivalent-to-tension-band-wire-in-the-fixation-of-transverse-patellar-fractures-a-cadaveric-study
#1
Fucai Han, Christopher Jon Pearce, David Q K Ng, Amit K Ramruttun, Desmond Y R Chong, Diarmuid Murphy, Chin Tat Lim, Bernard C S Lee
INTRODUCTION: Tension-band wire fixation of patellar fractures is associated with significant hardware-related complications and infection. Braided polyester suture fixation is an alternative option. However, these suture fixations have higher failure rates due to the difficulty in achieving rigid suture knot fixation. The Arthrex syndesmotic TightRope, which is a double-button adjustable loop fixation device utilizing a 4-point locking system using FibreWire, may not only offer stiff rigid fixation using a knotless system, but may also obviate the need for implant removal due to hardware related problems...
November 17, 2016: Injury
https://www.readbyqxmd.com/read/27882130/the-use-of-expanded-polytetrafluoroethylene-in-depressed-deformities-of-the-face
#2
Xiaowei Liu, Yiming Zhang, Shaoliang Wang, Zeyuan Lei, Xiang Li, Dongli Fan
Expanded polytetrafluoroethylene (ePTFE) has been extensively used for facial soft tissue augmentation procedures, and is regarded as safe and reliable and suitable as a permanent implant. This implant is generally used in the lower third of the face for lips filling, nasal augmentation, nasolabial folds and chin augmentation, and rarely for congenital or acquired depressed deformities of the face. The aim of the present study was to assess the effects of ePTFE in congenital or acquired depressed deformities of the face...
November 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27875549/the-synthetic-%C3%AE-nitrostyrene-derivative-cyt-rx20-inhibits-esophageal-tumor-growth-and-metastasis-via-pi3k-akt-and-stat3-pathways
#3
Wen-Chin Chiu, Yi-Chen Lee, Yu-Han Su, Yen-Yun Wang, Chun-Hao Tsai, Yi-An Hou, Chie-Hong Wang, Ying-Fong Huang, Chih-Jen Huang, Shah-Hwa Chou, Pei-Wen Hsieh, Shyng-Shiou F Yuan
The β-nitrostyrene family have been implicated for anti-cancer property. However, the pharmacological role of β-nitrostyrene in esophageal cancer remain unclear. Here, a β-nitrostyrene derivative, CYT-Rx20, was synthesized and assessed for its anti-cancer activities and underlying mechanism in esophageal cancer. CYT-Rx20 induced cytotoxicity in esophageal cancer cells by promoting apoptosis through activation of caspase cascade and poly(ADP-ribose) polymerase (PARP) cleavage. Besides, CYT-Rx20 inhibited esophageal cancer cell migration and invasion by regulating the expression of epithelial to mesenchymal transition (EMT) markers...
2016: PloS One
https://www.readbyqxmd.com/read/27865201/increased-risk-of-ventricular-tachycardia-in-patients-with-sarcoidosis-during-the-very-long-term-follow-up
#4
Abigail Louise D Te, Yenn-Jiang Lin, Yun-Yu Chen, Fa-Po Chung, Shih-Lin Chang, Li-Wei Lo, Yu-Feng Hu, Ta-Chuan Tuan, Tze-Fan Chao, Jo-Nan Liao, Chin-Yu Lin, Yao-Ting Chang, Kuo-Liong Chien, Shih-Ann Chen
BACKGROUND: Sarcoidosis is an important diagnostic consideration in patients with ventricular tachycardia (VT) of unknown origin. The clinical course of VT as the primary presentation in patients with sarcoidosis is mostly unknown. This study aimed to investigate the incidence of life-threatening VT and mortality during long term follow-up in patients with sarcoidosis. METHODS: We analyzed the epidemiological features of sarcoidosis in Taiwan using the National Health Insurance Research Database from 2000 to 2004...
November 7, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27806001/ocular-hypertension-after-intravitreal-dexamethasone-ozurdex-sustained-release-implant
#5
Eric K Chin, David R P Almeida, Gabriel Velez, Kunyong Xu, Maria Peraire, Maria Corbella, Yasser M Elshatory, Young H Kwon, Karen M Gehrs, H Culver Boldt, Elliott H Sohn, Stephen R Russell, James C Folk, Vinit B Mahajan
PURPOSE: To evaluate ocular hypertension (OHT) after Ozurdex injection to determine the incidence of OHT, therapy for OHT, and any associative factors such as diagnosis, underlying glaucoma and therapy, or sequential Ozurdex injection(s). METHODS: Retrospective consecutive case series with patients receiving one or more intravitreal Ozurdex implantations at a tertiary care academic center. Ocular hypertension was defined as a single measurement of ≥30 mmHg or an increase of ≥10 mmHg from baseline...
November 1, 2016: Retina
https://www.readbyqxmd.com/read/27766059/preimplantation-genetic-diagnosis-of-hemophilia-a
#6
Ming Chen, Shun-Ping Chang, Gwo-Chin Ma, Wen-Hsian Lin, Hsin-Fu Chen, Shee-Uan Chen, Horng-Der Tsai, Feng-Po Tsai, Ming-Ching Shen
Preimplantation genetic diagnosis (PGD) is a powerful tool to tackle the transmission of monogenic inherited disorders in families carrying the diseases from generation to generation. It currently remains a challenging task, despite PGD having been developed over 25 years ago. The major difficulty is it does not have an easy and general formula for all mutations. Different gene locus needs individualized, customized design to make the diagnosis accurate enough to be applied on PGD, in which the quantity of DNA is scanty, whereas timely laboratory diagnosis is mandatory if fresh embryo transfer is desired occasionally...
2016: Thrombosis Journal
https://www.readbyqxmd.com/read/27760646/-the-efficacy-of-large-spot-indirect-ophthalmoscopy-laser-alone-or-combined-with-systemic-chemotherapy-in-retinoblastoma-therapy
#7
J H Liang, Y Cheng, X Deng, Y Y Yu, X X Li
: Objective: To evaluate the efficacy of large spot indirect ophthalmoscopy laser alone or combined with systemic chemotherapy in the treatment of early and middle stage retinoblastoma. Methods: Retrospective series case study. Clinical data of 21 patients (22 eyes) who were diagnosed as retinoblastoma (RB) in Peking University People's Hospital from March 2009 to August 2014 were collected. Medical and family history, ocular ultrasound, orbital and cranial MRI or CT examination of RB Children were detailed recorded...
October 11, 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/27757017/intracerebroventricular-urocortin-3-counteracts-central-acyl-ghrelin-induced-hyperphagic-and-gastroprokinetic-effects-via-crf-receptor-2-in-rats
#8
Chun Yeh, Ching-Heng Ting, Ming-Luen Doong, Chin-Wen Chi, Shou-Dong Lee, Chih-Yen Chen
PURPOSE: Urocortin 3 is a key neuromodulator in the regulation of stress, anxiety, food intake, gut motility, and energy homeostasis, while ghrelin elicits feeding behavior and enhances gastric emptying, adiposity, and positive energy balance. However, the interplays between urocortin 3 and ghrelin on food intake and gastric emptying remain uninvestigated. METHODS: We examined the differential effects of central O-n-octanoylated ghrelin, des-Gln(14)-ghrelin, and urocortin 3 on food intake, as well as on charcoal nonnutrient semiliquid gastric emptying in conscious rats that were chronically implanted with intracerebroventricular (ICV) catheters...
2016: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/27755406/porous-polyethylene-implant-as-aesthetic-complement-in-orthognathic-surgery
#9
Juliana Dreyer da Silva de Menezes, Lucas Borin Moura, Renato Parsekian Martins, Eduardo Hochuli-Vieira
Porous polyethylene implants have been used as an alternative in the treatment of patients with zygomatic and paranasal projections deficiency. These implants promote a facial rejuvenating effect due to the attenuation of the nasal and chin prominences. The advantages of porous polyethylene include biocompatibility, dimensional stability, easy adaptation and fixation, low complication rate, and its availability in different sizes and shapes. A 27-year-old woman presenting vertical deficiency associated with midface hypoplasia was treated with orthognathic surgery...
October 14, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27738534/hard-and-soft-tissue-management-of-a-localized-alveolar-ridge-atrophy-with-autogenous-sources-and-biomaterials-a-challenging-clinical-case
#10
C Maiorana, D Andreoni, P P Poli
Particularly in the premaxillary area, the stability of hard and soft tissues plays a pivotal role in the success of the rehabilitation from both a functional and aesthetic aspect. The present case report describes the clinical management of a localized alveolar ridge atrophy in the area of the upper right canine associated with a thin gingival biotype with a lack of keratinized tissue. An autogenous bone block harvested from the chin associated with heterologous bone particles was used to replace the missing bone, allowing for a prosthetic driven implant placement...
2016: Case Reports in Dentistry
https://www.readbyqxmd.com/read/27709870/avoiding-errors-in-the-management-of-pediatric-polytrauma-patients
#11
Kenneth Chin, Joshua M Abzug, Donald S Bae, Bernard D Horn, Martin Herman, Craig P Eberson
Management of pediatric polytrauma patients is one of the most difficult challenges for orthopaedic surgeons. Multisystem injuries frequently include complex orthopaedic surgical problems that require intervention. The physiology and anatomy of children and adolescent trauma patients differ from the physiology and anatomy of an adult trauma patient, which alters the types of injuries sustained and the ideal methods for management. Errors of pediatric polytrauma care are included in two broad categories: missed injuries and inadequate fracture treatment...
February 15, 2016: Instructional Course Lectures
https://www.readbyqxmd.com/read/27687806/do-conversion-total-hip-arthroplasty-yield-comparable-results-to-primary-total-hip-arthroplasty
#12
Ran Schwarzkopf, Garwin Chin, Kelvin Kim, Dermot Murphy, Antonia F Chen
BACKGROUND: The incidence of hip fractures is growing with the increasing elderly population. Typically, hip fractures are treated with open reduction internal fixation, hemiarthroplasty, or total hip arthroplasty (THA). Failed hip fracture fixation is often salvaged by conversion THA. The total number of conversion THA procedures is also supplemented by its use in treating different failed surgical hip treatments such as acetabular fracture fixation, Perthes disease, slipped capital femoral epiphysis, and developmental dysplasia of the hip...
September 1, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/27684483/two-year-durability-after-crossover-to-the-prostatic-urethral-lift-from-randomized-blinded-sham
#13
Daniel Rukstalis, Prem Rashid, William Bogache, Ronald Tutrone, Jack Barkin, Peter Chin, Henry Woo, Anthony Cantwell, Barrett Cowan, Damien Bolton
PURPOSE: To evaluate the 2 year effectiveness of the Prostatic Urethral Lift (PUL) procedure in men with lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) assessed through a crossover study. METHODS: Fifty-three patients underwent sham procedure as part of the blinded, randomized L.I.F.T. study at 19 centers and elected to enroll in this crossover study. The crossover procedure involved placement of permanent implants (UroLift(®) System) into the prostatic lateral lobes...
September 29, 2016: BJU International
https://www.readbyqxmd.com/read/27680524/solid-implants-in-facial-plastic-surgery-potential-complications-and-how-to-prevent-them
#14
Krishna Patel, Kathleyn Brandstetter
Allogenic implants are an effective alternative to autologous grafts in the reconstruction of facial defects. These implants are used to reconstruct a variety of bony and soft-tissue defects, including the frontal and temporal regions; internal orbit; infraorbital rim; malar, paranasal, and nasal regions; mandible; and chin. In comparison to their autologous counterparts, alloplastic materials are more readily available, lack donor-site morbidity, decrease surgical time and cost, and still have relatively good postoperative tissue tolerance...
October 2016: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/27680522/choosing-the-best-procedure-to-augment-the-chin-is-anything-better-than-an-implant
#15
Jonathan M Sykes, Rebecca Fitzgerald
The chin plays a very important role in overall facial appearance, and aesthetic procedures to augment the chin in patients with microgenia can improve overall facial balance. Many procedures exist to enhance the appearance of a small chin. Procedures include surgeries such as placement of an alloplast implant and bony osteotomy of the mentum (sliding genioplasty). The advantages and disadvantages of each surgical technique are well documented. Although surgical augmentation of the chin has been the gold standard of therapy, recent development of injectable filler products with lifting capacity has changed the way that many practitioners alter chin shape and size...
October 2016: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/27642816/clinical-outcomes-with-midline-cortical-bone-trajectory-pedicle-screws-versus-traditional-pedicle-screws-in-moving-lumbar-fusions-from-hospitals-to-outpatient-surgery-centers
#16
Kingsley R Chin, Fabio J R Pencle, André V Coombs, Mohamed Elsharkawy, Corrine F Packer, Elijah A Hothem, Jason A Seale
STUDY DESIGN: Level III. OBJECTIVE: To report on the outcomes of midline cortical bone trajectory (CBT) pedicle screw surgical technique for posterior lumbar fixation in the outpatient surgery center (OSC) compared with traditional pedicle screws in the hospital. SUMMARY OF BACKGROUND DATA: Traditional pedicle screws have been the gold standard for posterior lumbar fusion. Advances in spine surgery, including less invasive procedures have propelled the design of instruments and implants to achieve greater posterior spinal fixation, with decreased tissue destruction and higher safety margins...
September 16, 2016: Clinical Spine Surgery
https://www.readbyqxmd.com/read/27623429/incidence-of-modern-alumina-ceramic-and-alumina-matrix-composite-femoral-head-failures-in-nearly-6-million-hip-implants
#17
Gwo-Chin Lee, Raymond H Kim
BACKGROUND: Because of improvements in ceramic materials and manufacturing, the incidence of ceramic failures has decreased over time. Recent concerns with corrosion have contributed to an increase in ceramic ball head utilization. The purpose of this study is to report the incidence of modern alumina bearing failures from a single major ceramic manufacturer in nearly 6 million hip implants and to identify trends in the modes of failure of these implants. METHODS: Beginning in the year 2000, CeramTec AG (Plochingen, Germany) began a comprehensive program for reporting and gathering failure data on its products...
August 20, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/27605343/high-estradiol-concentrations-induce-heat-shock-protein-70-expression-and-suppress-nuclear-factor-kappa-b-activation-in-human-endometrial-epithelial-cells
#18
Chin-Der Chen, Shee-Uan Chen, Chia-Hung Chou, Mei-Jou Chen, Wen-Fen Wen, Szu-Yuan Wu, Yu-Shih Yang, Jehn-Hsiahn Yang
The high serum estradiol (E2) concentrations induced during in vitro fertilization are detrimental to endometrial receptivity and may result in lower embryo implantation rates. We have previously found that high E2 concentrations inhibit the activation of nuclear factor kappa B (NF-kappa B), which led to endometrial epithelial cells (EECs) apoptosis. The objective of this study is to investigate the signaling pathways through which high E2 results in NF-kappa B downregulation in EECs. Isolated human EECs were cultured in different concentrations of E2 (10(-10), 10(-9), 10(-8), 10(-7) M)...
September 7, 2016: Biology of Reproduction
https://www.readbyqxmd.com/read/27554366/assessment-of-pain-perception-following-periodontal-and-implant-surgeries
#19
Chih-Chun Mei, Fu-Ying Lee, Hwey-Chin Yeh
OBJECTIVE: To evaluate patients' pain perception following periodontal or implant surgery and to explore risk factors associated with post-surgical pain. MATERIALS AND METHODS: Patients undergoing periodontal or implant surgery were recruited. Post-surgical pain perception was evaluated by a numeric rating scale (NRS, 1-10) after 1 week. Self-reported durations of pain (DOP) and of swelling (DOS), and consumption of prescriptions were also recorded. Demographic and surgical variables were compared between the groups of mild (MP) and moderate-to-severe post-surgical pain (SP)...
August 24, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27537226/do-prolonged-prophylactic-antibiotics-reduce-the-incidence-of-surgical-site-infections-in-immediate-prosthetic-breast-reconstruction
#20
Frederick Wang, Robin Chin, Merisa Piper, Laura Esserman, Hani Sbitany
BACKGROUND: Approximately 50,000 women per year in the United States undergo mastectomy and immediate prosthetic breast reconstruction, and most will receive prolonged prophylactic antibiotics. The effect of this practice on the risk of surgical site infections (SSIs) remains unclear. METHODS: We searched the Medline, Embase, and Cochrane Library databases for studies that compared <24 hours and >24 hours of antibiotics in cases of immediate prosthetic breast reconstruction...
August 15, 2016: Plastic and Reconstructive Surgery
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