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https://www.readbyqxmd.com/read/28533580/olanzapine-induced-neuroleptic-malignant-syndrome
#1
Seyedhamze Hosseini, Forouzan Elyasi
Neuroleptic malignant syndrome (NMS) is a rare but life-threatening idiosyncratic side effect resulting from neuroleptic drugs. NMS mainly occurs in patients treated with high-potency typical antipsychotics, but rarely caused by atypical antipsychotics. Although NMS is less common with atypical antipsychotic, but it seems that its incidence is rising due to increased administration of such drugs. We present the case of a 27-year-old man with a history of paranoid schizophrenia that showed signs consistent with NMS that occurred after treatment with olanzapine...
May 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28532969/lip-reconstruction-using-a-functioning-serratus-anterior-free-flap-preliminary-study
#2
A O Gundeslioglu, E C Karadag, I Inan, L Jasharllari, M N Selimoglu, F Guney, B Yuruten, M Bekerecioglu
Reconstructive surgery to the lips requires the replacement of defective tissues with similarly functioning tissues. While non-dynamic free tissue transfers provide adequate lower lip reconstruction, improved benefits may be obtained with innervated free muscle flaps. This study reports the use of innervated serratus anterior muscle free flaps for lip reconstruction in five patients. All patients had squamous cell carcinoma of either the upper or lower lip. After resection of the tumours, the resultant defects comprised two-thirds of the lips...
May 19, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28531866/bilateral-peritonsillar-abscess-a-case-report-and-pertinent-literature-review
#3
Ibrahim AlAwadh, Turki Aldrees, Saleh AlQaryan, Sami Alharethy, Hassan AlShehri
INTRODUCTION: The peritonsillar space is defined as the area between the palatine tonsillar capsule medially and the superior pharyngeal constrictor muscle laterally. Unilateral peritonsillar abscess (PTA) is more common than the bilateral condition. To the best of our knowledge, only 13 cases of bilateral PTA have been reported worldwide; this is the first case reported from Saudi Arabia. PRESENTATION OF CASE: We present a case involving a 16-year-old boy who presented to the emergency department with a5-day history of sore throat, dysphagia, trismus, drooling, and a muffled "hot-potato" voice, but with no symptoms of airway compromise...
May 15, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28530322/-oro-dento-facial-manifestations-in-patients-with-familial-dysautonomia
#4
REVIEW
Eliyahu Mass
The oro-dento-facial features and dysfunctions of children with hereditary sensory and autonomic neuropathy type III (HSAN III), known as familial dysautonomia (FD) or Riley-Day syndrome, were first described in the scientific literature in 1949. They include: dental trauma, dental and soft tissue selfmutilation, normal dental age, normal sequence and timing of eruption and exfoliation of teeth, smaller tooth size, different and disproportional tooth components, normal alveolar bone height, small jaws, mild crowding and malocclusion...
August 2016: Harefuah
https://www.readbyqxmd.com/read/28489832/caustic-ingestion-in-children-in-south-of-iran-retrospective-study-from-shiraz-iran
#5
Naser Honar, Mahmood Haghighat, Samaneh Mahmoodi, Hazhir Javaherizadeh, Gholamreza Kalvandi, Mohammad Salimi
Caustic ingestion is a major health concern in both developed and developing countries, that may lead to serious esophageal injury. The clinical presentation of caustic ingestion in children vary from asymptomatic to serious and fatal sequelae, such as perforation and stricture formation. OBJECTIVE: Due to the lack of a comprehensive study in our area, this study has evaluated clinical and endoscopic manifestations and complications of caustic ingestion in children in south of Iran. MATERIALS AND METHODS: In this retrospective study, we reviewed 75 children with caustic ingestion who admitted in Nemazee Hospital of Shiraz University of Medical Science during 6 years (2006-2011)...
January 2017: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/28458496/chronic-recurrent-non-specific-parotitis-a-case-report-and-review
#6
Saibaba Mahalakshmi, Srinivas Kandula, Patil Shilpa, Ganganna Kokila
BACKGROUND: Chronic recurrent non-specific parotitis is characterized by recurrent episodes of swelling and pain of unknown etiology in the parotid gland. Sialography is a hallmark in the diagnosis of salivary gland disorders; newer imaging modalities like CT-Sialography, sialoendoscopy and MRI can be used. Various treatment modalities have been tried, from conservative approach to surgical excision depending on the recurrence rate and severity of the condition. Although symptomatic treatment with antibiotics and analgesic, injection of intraductal medicament, aggressive treatment like duct ligation or excision of gland are some of the treatment modalities, there is no established algorithm as to which treatment method should be opted in such clinical situation...
January 2017: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/28446482/secondary-parkinsonism-in-a-patient-of-psychogenic-polydipsia
#7
Rimesh Pal, Liza Das, Pinaki Dutta, Anil Bhansali
A 44-year-old man presented with history of slurring of speech, slowness in activities, abnormal posturing of the upper limbs and drooling of saliva from the mouth. He had a 5-yearlong history of compulsive water drinking, consuming 12-15 L of water every day. He was earlier evaluated for the same and found to have low serum sodium (126 mEq/L). Presently, he was admitted at a primary care facility with fever and altered sensorium. He was found to have serum sodium of 94 mEq/L. His sensorium improved with hypertonic saline infusion; however, after a lucid interval of 48 hours, he developed florid extrapyramidal symptoms...
April 26, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28437012/leptin-and-ngf-in-saliva-of-patients-with-diabetes-mellitus-type-2-a-pilot-study
#8
Tvarijonaviciute Asta, Candela Castillo, Jose J Ceron, Silvia Martinez-Subiela, Fernando Tecles, Pia López-Jornet
AIMS: This study aimed to measure salivary levels of leptin and NGF in patients with type 2 diabetes (T2D) and to compare with healthy subjects. In addition, markers previously evaluated in diabetes, including insulin, HGF and MCP-1, and markers of inflammation (IL-1b, IL-6, IL-8, TNF-α), were also measured in saliva in order to evaluate possible relationship of these markers with the new analytes evaluated in the study. METHODS: Unstimulated whole saliva was collected by passive drooling from a total of 65 individuals (34 controls and 31 with T2D) and used for leptin, NGF, HGF, MCP-1, insulin, IL-1b, IL-6, IL-8, and TNF-α determination...
April 24, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/28414689/radiology-case-of-the-month-mental-disturbance-for-4-days
#9
Matthew Brunner, Enrique Palacios, Harold Neitzschman, Jeremy Mguyen
A 56 year old African-American man presented to the emergency department with dyspnea and dysphagia with drooling. On his initial evaluation, disproportionate obesity of the face, neck and shoulders were noted. The patient's history was significant for obstructive sleep apnea, end-stage renal disease, alcoholic liver disease, pulmonary hypertension and alcoholic cardiomyopathy. He had multi-decade history of heavy alcohol abuse, but quit drinking two years previously.
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28396971/what-sleep-behaviors-are-associated-with-bruxism-in-children-a-systematic-review-and-meta-analysis
#10
REVIEW
Huaqi Guo, Tongxia Wang, Xuechao Li, Qiong Ma, Xiaohong Niu, Jie Qiu
PURPOSE: The aim of this article was to assess the sleep behaviors that serve as risk factors related to bruxism in children ages 0 to 12 years by performing a systematic review and meta-analysis of published studies. METHODS: Seven databases were searched to identify all peer-reviewed articles potentially relevant to the review. Data were pooled for random-effects modeling. Sleep risk factors related to bruxism in this age group are summarized using pooled odds ratios (ORs), 95% confidence intervals (CIs), and P values...
April 10, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28393503/-bilateral-submandibulectomy-for-the-treatment-of-drooling-in-pediatric-age-10-years-of-experience
#11
A S Marinho, C Sousa, A Coelho, J Barbosa-Sequeira, M Recamán, F Carvalho
INTRODUCTION: Sialorrhea is a medical problem and can become a social issue, common in children with neurological disabilities. The bilateral submandibulectomy is one of the available treatment options for managing this pathology. AIM OF THE STUDY: The aim of this study is to evaluate the effectiveness of bilateral submandibulectomy in the management of sialorrhea in children with neurological disabilities through the parents' satisfaction grade. PATIENTS AND METHODS: We retrospectively analyzed 91 bilateral submandibulectomies for a period of time of 10 years (2004-2015)...
July 10, 2016: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/28380387/metabolite-quantification-by-nmr-and-lc-ms-ms-reveals-differences-between-unstimulated-stimulated-and-pure-parotid-saliva
#12
João Figueira, Sandra Gouveia-Figueira, Carina Öhman, Pernilla Lif Holgerson, Malin L Nording, Anders Öhman
Saliva is a readily available biofluid that is sensitive to metabolic changes and can be collected through rapid and non-invasive collection procedures, and it shows great promise for clinical metabolomic studies. This work studied the metabolite composition of, and the differences between, saliva samples collected by unstimulated spitting/drooling, paraffin chewing-stimulated spitting, and parotid gland suction using targeted nuclear magnetic resonance (NMR) spectroscopy and liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) for metabolite quantification...
June 5, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28359354/supplementation-with-concentrated-milk-protein-in-patients-undergoing-hematopoietic-stem-cell-transplantation
#13
Ana Carolina Amaral de São José Perrone, Thaís Rodrigues Barbosa, Fernanda Lopes da Silva, Ítalo Tuler Perrone, Antônio Fernandes de Carvalho, Rodrigo Stephani, Kelli Borges Dos Santos, Ângelo Atalla, Abrahão Elias Hallack Neto
OBJECTIVE: The aim of this study was to analyze the influence of dietary supplementation with whey protein concentrate (WPC) in the incidence of oral mucositis (OM) in patients undergoing hematopoietic stem cell transplantation (HSCT). METHODS: Patients were supplemented with a daily intake of WPC delivering 50% of the daily protein requirements (DPR) according to the Dietary Reference Intakes and classified later based on the amount of ingested supplement until OM median onset...
May 2017: Nutrition
https://www.readbyqxmd.com/read/28342306/rotigotine-may-control-drooling-in-patients-with-parkinson-s-disease-preliminary-findings
#14
Tommaso Schirinzi, Paola Imbriani, Alessio D'Elia, Giulia Di Lazzaro, Nicola Biagio Mercuri, Antonio Pisani
OBJECTIVE: To evaluate the efficacy of rotigotine in controlling the drooling of Parkinson's Disease (PD) patients. PATIENTS AND METHODS: We assessed 7 PD patients (Hoehn and Yahr scale >2.5) with three different clinical scores (Drooling Severity and Frequency Scale - DSFS, Drooling Rating Scale - DRS and Sialorrhea Clinical Scale for PD - SCS) before and after 4 weeks of therapy. Statistical differences were analyzed with Wilcoxon signed-rank test. RESULTS: We observed that rotigotine significantly improves drooling as measured by the lowering of the three scores (p<0...
May 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28330576/-interests-of-the-ultrasound-guidance-in-the-treatment-of-drooling-through-botulinum-toxin-injections-our-experience-over-10%C3%A2-years
#15
M Mailly, C Rebours, P Koskas, P Klap, D Ayache, M Cohen
OBJECTIVES: To report about our 10 years' experience about the treatment of drooling by ultrasound guided botulinum toxin injections. MATERIAL AND METHODS: Retrospective monocentric study including all the patients suffering from drooling and treated by ultrasound-guided botulinum toxin injections into the salivary glands between 2004 and 2015. The etiology of r drooling, the doses of toxin, the injected glands, the size of the glands measured by ultrasonography, the effectiveness of the treatment and the side effects were assessed...
February 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28318199/-foreign-body-in-the-esophagus-as-a-cause-of-respiratory-symptoms-in-children-clinical-cases
#16
Giselle Cuestas, Verónica Rodríguez, Flavia Doormann, Patricio Bellia Munzón, Gastón Bellia Munzón
Foreign bodies in esophagus are avoidable accidents that occur most often in children younger than 3 years. The most common presenting symptoms are dysphagia, drooling and vomiting. Occasionally a foreign body in the esophagus may present with respiratory symptoms such as cough, stridor and respiratory distress. This is more common in young children and when the object remains lodged in the esophagus for a prolonged period. Clinical suspicion is essential for early diagnosis, which allows to avoid potential complications...
April 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28315649/comparison-of-saliva-collection-methods-for-the-determination-of-salivary-cortisol-levels-in-rhesus-macaques-macaca-mulatta-cynomolgus-macaques-macaca-fascicularis-and-african-green-monkeys-chlorocebus-aethiops
#17
Kamala J Rapp-Santos, Louis A Altamura, Sarah L Norris, Luis A Lugo-Roman, Pedro J Rico, Christian C Hofer
The ability to quickly and accurately determine cortisol as a biomarker for stress is a valuable tool in assessing the wellbeing of NHP. In this study, 2 methods of collecting saliva (a commercial collection device and passive drool) and the resulting free salivary cortisol levels were compared with total serum cortisol concentration in rhesus macaques (Macaca mulatta), cynomolgus macaques (Macaca fascicularis) and African green monkeys (Chlorocebus aethiops) at 2 collection time points. Serum and salivary cortisol levels were determined using a competitive quantitative ELISA...
March 1, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/28304087/feasibility-of-endoscopic-submandibular-ganglion-neurectomy-for-drooling
#18
Kayhan Ozturk, Omer Erdur, Osman Gul, Ayse Olmez
We performed endoscopic transoral neurectomy of the submandibular and sublingual glands to treat drooling. We bilaterally operated two adult cases with treatment-resistant drooling. In these patients, conventional treatment had failed. Repeated botilinum toxin type A (BOTOX®, Abdi Ibrahim Pharmaceutical Company, Istanbul, Turkey) injections had been effective but were becoming less so. The patients benefited from surgery in that their saliva scores decreased. No issue emerged over 6 months of follow-up. Endoscopic transoral neurectomy of the submandibular and sublingual glands reduces saliva production and allows management of drooling in treatment-resistant patients...
March 17, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28289635/accuracy-of-ultrasound-guided-and-non-ultrasound-guided-botulinum-toxin-injection-into-cadaver-salivary-glands
#19
Jae In So, Dae Heon Song, Joo Hyun Park, Eunseok Choi, Jung Yoon Yoon, Yeonji Yoo, Myung Eun Chung
OBJECTIVE: To compare the accuracy of ultrasound (US)-guided and non-US-guided botulinum toxin (BTX) injection into the salivary glands (parotid and submandibular glands) of cadavers. METHODS: Two rehabilitation physician injected dye into three sites in the salivary glands (two sites in the parotid gland and one site in the submandibular gland) on one side of each cadaver (one was injected on the right side, while the other was injected on the left side), using either a non-US-guided injection procedure based on superficial landmarks or a US-guided procedure...
February 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28277296/botox-a-injection-of-salivary-glands-for-drooling
#20
Ana Alvarenga, Miguel Campos, Mariana Dias, Lina Melão, José Estevão-Costa
BACKGROUND AND PURPOSE: Drooling is a challenging entity to manage. Botulinum toxin A (BOTOX-A) infiltration of salivary glands is a promising alternative to surgical treatment. This study aims to assess the outcome of BOTOX-A salivary glands infiltration in children with drooling. METHODS: Patients treated between January 2012 and March 2015 were enrolled. BOTOX-A was injected in the parotid and submandibular glands under ultrasound control and general inhalational anesthesia...
October 14, 2016: Journal of Pediatric Surgery
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