Vitan Blagotinsek, Meike Schwan, Wieland Steinchen, Devid Mrusek, John C Hook, Florian Rossmann, Sven A Freibert, Hanna Kratzat, Guillaume Murat, Dieter Kressler, Roland Beckmann, Morgan Beeby, Kai M Thormann, Gert Bange
Bacterial flagella differ in their number and spatial arrangement. In many species, the MinD-type ATPase FlhG (also YlxH/FleN) is central to the numerical control of bacterial flagella, and its deletion in polarly flagellated bacteria typically leads to hyperflagellation. The molecular mechanism underlying this numerical control, however, remains enigmatic. Using the model species Shewanella putrefaciens , we show that FlhG links assembly of the flagellar C ring with the action of the master transcriptional regulator FlrA (named FleQ in other species)...
August 11, 2020: Proceedings of the National Academy of Sciences of the United States of America