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https://www.readbyqxmd.com/read/29775450/-congenital-megacalycosis-in-a-girl-with-unilateral-renal-agenesis
#1
Agnieszka Szmigielska, Grażyna Krzemień, Anna Zacharzewska, Teresa Dudek-Warchoł, Stanisław Warchoł
Renal agenesis occurs in pediatric population with the incidence 1:500- 2000 children. It is more often diagnosed in boys and on the left side of the body. Renal agenesis may be isolated or it may be a part of complex malformation syndrome. Megacalycosis is a very rare anomaly of urinary tract associated with abnormal structure of the kidney pyramids. AIM: The aim of the study was to present for the first time in the medical literature the case of a girl with unilateral renal agenesis and megacalycosis...
April 23, 2018: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29774942/-progress-and-controversy-on-diagnosis-and-treatment-of-gastric-stump-cancer
#2
Zhidong Gao, Yongbai Li, Kewei Jiang, Yingjiang Ye, Shan Wang
Gastric stump cancer (GSC) is a carcinoma arising from the remnant stomach following gastric surgery for benign or malignant disease, and is more common in men. The risk of morbidity has an obvious time dependence. GSC incidence is likely to rise with lengthening of the initial operation interval. The GSC time interval after malignant disease is significantly shorter than that of benign disease. GSC etiologies mainly include duodenogastric reflux and denervation of the gastric mucosa resulting in the change of the gastric environment after gastrectomy and the Helicobacter pylori infection...
May 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29774929/-epidemiological-characteristics-and-inducing-factors-of-gastric-stump-cancer
#3
Lin Chen
Gastric stump cancer was initially defined as a carcinoma of the stomach occurring more than 5 years after surgery for gastric or duodenal benign disease. In recent years, as the number of total gastrectomy for benign disease has gradually decreased and the gastric cancer detection and operation rate have annually increased, residual recurrence of primary gastric cancer more than 10 years after gastric cancer surgery has also been considered as gastric stump cancer. The incidence of gastric stump cancer is increasing annually...
May 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29774563/alternative-therapies-for-gerd-a-way-to-personalized-antireflux-surgery
#4
Erwin Rieder, Martin Riegler, Aleksandar P Simić, Ognjan M Skrobić, Luigi Bonavina, Richard Gurski, Matthias Paireder, Donald O Castell, Sebastian F Schoppmann
Gastroesophageal reflux disease (GERD) is a common disorder, known to affect about 20% of the Western population. Although conventional medical or surgical treatment has proven effective, there is certainly room for improvements. As only 10% of GERD patients are finally treated by antireflux surgery, a large therapeutic window exists. This treatment gap consists of patients who are not effectively treated with proton pump inhibitor but do not want to run the potential risks of conventional surgery. During the last two decades, several novel and intriguing options for the surgical treatment of GERD have been introduced and found their way into clinical use...
May 17, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29774149/the-rome-iv-versus-rome-iii-criteria-for-heartburn-diagnosis-a-comparative-study
#5
Mengyu Zhang, Minhu Chen, Sui Peng, Yinglian Xiao
Background: The phenotypes of heartburn patients are heterogeneous. Objective: The objective of this study was to investigate the proportion of heartburn phenotypes in a Chinese population and to compare the Rome IV and III criteria for heartburn diagnosis. Methods: A retrospective study was performed among heartburn patients referred for upper endoscopy and esophageal function tests in a tertiary hospital. Their symptoms fulfilled Rome IV and III criteria...
April 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29773294/gastroesophageal-reflux-symptoms-and-nasal-symptoms-affect-the-severity-of-bronchitis-symptoms-in-patients-with-chronic-obstructive-pulmonary-disease
#6
Koichi Hasegawa, Susumu Sato, Kazuya Tanimura, Yoshinori Fuseya, Kiyoshi Uemasu, Yoko Hamakawa, Atsuyasu Sato, Michiaki Mishima, Shigeo Muro, Toyohiro Hirai
BACKGROUND: Cough and sputum production (symptoms of bronchitis) are common in chronic obstructive pulmonary disease (COPD). Extrapulmonary comorbidities, such as gastroesophageal reflux disease (GERD) and post-nasal drip, also cause bronchitis symptoms. The impact of extrapulmonary comorbidities on the severity of bronchitis symptoms in COPD is unknown. The aim of this study was to quantify bronchitis symptoms and assess the impact of GERD and nasal symptoms on the severity of bronchitis symptoms in COPD...
May 2018: Respiratory Investigation
https://www.readbyqxmd.com/read/29773017/gastroesophageal-reflux-disease-a-review-of-symptomatic-management
#7
Elsa S Tabrez, Azhar Hussain, Seetharama Rao, Ashraya Jagadeesh, Jagannadha Rao Peela, Shams S M Tabrez
Considered as a chronic illness, gastroesophageal reflux disease (GERD) has manifested itself as a widespread condition throughout the adult population. As a growing epidemic, GERD has reached a staggering prevalence of 10% to 20% in the Western world, by affecting up to 30 million people in the United States alone. Sixty percent of individuals in an adult population will experience symptoms and the impact of GERD over a period of 12 months, whereas a remarkable 20% to 30% of individuals will have weekly symptoms...
2018: Critical Reviews in Eukaryotic Gene Expression
https://www.readbyqxmd.com/read/29772321/use-of-polidocanol-endovenous-microfoam-to-improve-hemodynamics-and-symptomology-in-patients-with-challenging-clinical-presentations-a-case-series
#8
Paul E Davis, John Phillips, Raghu Kolluri
BACKGROUND: We performed a retrospective review of treatment effects with FDA-approved Polidocanol endovenous microfoam (PEM, Varithena® 1%) on venous symptomology in ten (N=10) C3-C6 patients with chronic venous insufficiency (CVI) and concomitant complex disease/pathology that limited the use of endothermal ablation (ETA). METHODS: Pathology included: risk of bruising or bleeding, severe lipodermatosclerosis (LDS), Hydradenitis Suppurativa, chronic fibrosis of the vein from prior superficial thrombosis, risk for nerve injury and failed prior ETA...
May 14, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29770925/esophageal-magnetic-sphincter-augmentation-as-a-novel-approach-to-post-bariatric-surgery-gastroesophageal-reflux-disease
#9
John P Kuckelman, Cody J Phillips, Michael J Derickson, Byron J Faler, Matthew J Martin
BACKGROUND: We sought to evaluate the safety and effectiveness of magnetic sphincter augmentation (MSA) in patients with GERD after bariatric surgery. METHODS: Pre- and post-operative GERD quality of life (G-QOL) surveys were conducted. Standard indications (SI) group or the post-bariatric group (PB) created. Outcomes were compared between groups. RESULTS: Twenty-eight patients analyzed with no losses to follow-up. All patients had preoperative testing confirming normal motility and presence of GERD...
May 16, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29770281/intestinal-spirochetosis-in-an-immunocompetent-patient
#10
Patricia Guzman Rojas, Jelena Catania, Jignesh Parikh, Tran C Phung, Glenn Speth
Intestinal spirochetosis (IS) is an infestation defined by the presence of spirochetes on the surface of the colonic mucosa. The implicated organisms can be Brachyspira aalborgi or Brachyspira pilosicoli . We present the case of a 66-year-old man with a past medical history of diabetes mellitus, hypertension, morbid obesity, and gastroesophageal reflux. The patient was sent to the gastroenterology clinic for a screening colonoscopy due to a prior history of colonic polyps. The patient was completely asymptomatic as he denies any abdominal pain, diarrhea, melena, or hematochezia...
March 15, 2018: Curēus
https://www.readbyqxmd.com/read/29768736/change-of-signs-symptoms-and-voice-quality-evaluations-throughout-a-3-to-6-months-empirical-treatment-for-laryngopharyngeal-reflux-disease
#11
Jérôme R Lechien, Camille Finck, Mohamad Khalife, Kathy Huet, Véronique Delvaux, Myriam Picalugga, Bernard Harmegnies, Sven Saussez
OBJECTIVE: To assess the usefulness of voice quality measurements as a treatment outcome in patients with laryngopharyngeal reflux (LPR)-related symptoms. DESIGN: Prospective uncontrolled multi-center study. MATERIAL AND METHODS: A total of 80 clinically diagnosed LPR patients with a reflux finding score (RFS)>7 and a reflux symptom index (RSI)>13 were treated with pantoprazole and diet recommendations during 3 or 6 months according to their evolution...
May 16, 2018: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29766521/current-and-future-perspectives-in-the-management-of-gastroesophageal-reflux-disease
#12
REVIEW
Junichi Akiyama, Shiko Kuribayashi, Myong Ki Baeg, Nicola de Bortoli, Elen Valitova, Edoardo V Savarino, Motoyasu Kusano, George Triadafilopoulos
Although the prevalence of gastroesophageal reflux disease (GERD) used to be lower in East Asia as compared to Western countries, it has recently been increasing, most likely due to the socioeconomic development in the East. The prevalence of both GERD and functional gastrointestinal disorders (FGIDs) ranges between 10% and 25% worldwide and there are distinct subgroups of patients with overlapping of GERD and FGIDs. However, the true prevalence of an overlap between GERD and FGIDs can be determined only when a formal pathophysiological evaluation has been performed...
May 16, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29766511/relevance-of-histology-in-the-diagnosis-of-reflux-esophagitis
#13
REVIEW
Monika Tripathi, Catherine J Streutker, E Celia Marginean
Reflux esophagitis is an important clinical diagnosis; however, the histologic findings can be nonspecific and overlap with other entities. Various benign changes can produce diagnostic difficulties for pathologists. In this review, the typical histologic findings of gastroesophageal reflux disease (GERD) of the esophagus are discussed, along with the issues relating to clinical correlation and technical aspects of endoscopic biopsies and specimen processing. The literature has been reviewed to discuss histologic definitions of GERD as well as current and developing controversies in the area of GERD...
May 16, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29766506/unique-causes-of-esophageal-inflammation-a-histopathologic-perspective
#14
REVIEW
Purva Gopal, Joanna A Gibson, Mikhail Lisvosky, ILKe Nalbantoglu
Gastroenterologists frequently perform endoscopic esophageal mucosal biopsies for pathologic diagnosis in patients experiencing symptoms of esophagitis. The more common causes of esophagitis diagnosed on esophageal mucosal biopsy include reflux esophagitis, eosinophilic esophagitis, and infectious esophagitis caused by Candida albicans, herpes simplex virus, and/or cytomegalovirus. However, there are several causes of esophagitis seen less frequently by pathologists that are very important to recognize. We discuss unique types of esophageal inflammation, including acute bacterial esophagitis, esophageal manifestations of dermatologic diseases, medication-induced esophageal injury, and sloughing esophagitis; and we review their clinical and histopathologic features...
May 16, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29763274/eosinophilic-esophagitis-a-mimic-of-gastroesophageal-reflux-disease
#15
Steven Clayton, John F Emerson
No abstract text is available yet for this article.
May 15, 2018: American Family Physician
https://www.readbyqxmd.com/read/29762301/effectiveness-of-nissen-fundoplication-versus-anterior-and-posterior-partial-fundoplications-for-treatment-of-gastro-esophageal-reflux-disease-a-systematic-review-protocol
#16
Matthew Marshall-Webb, Micah D J Peters, Tim Bright, David I Watson
The objective of this review is to determine the relative effectiveness of Nissen fundoplication compared to anterior and posterior partial fundoplication in controlling the symptoms of gastro-esophageal reflux disease and reducing their side effect profile in adults.The specific questions posed by this review are: what is the effectiveness of Nissen fundoplication in comparison to anterior partial fundoplication (90 degree, 120 degree and 180 degree) and posterior 270 degree fundoplication in terms of symptom control of gastro-esophageal reflux disease, and what are the side effects of these surgical interventions?...
May 2018: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29761528/nonerosive-reflux-disease-clinical-concepts
#17
REVIEW
C Prakash Gyawali, Dan E Azagury, Walter W Chan, Servarayan M Chandramohan, John O Clarke, Nicola de Bortoli, Edgar Figueredo, Mark Fox, Daniela Jodorkovsky, Adriana Lazarescu, Peter Malfertheiner, Jan Martinek, Kenric M Murayama, Roberto Penagini, Edoardo Savarino, Katerina P Shetler, Ellen Stein, Roger P Tatum, Justin Wu
Esophageal symptoms can arise from gastroesophageal reflux disease (GERD) as well as other mucosal and motor processes, structural disease, and functional esophageal syndromes. GERD is the most common esophageal disorder, but diagnosis may not be straightforward when symptoms persist despite empiric acid suppressive therapy and when mucosal erosions are not seen on endoscopy (as for nonerosive reflux disease, NERD). Esophageal physiological tests (ambulatory pH or pH-impedance monitoring and manometry) can be of value in defining abnormal reflux burden and reflux-symptom association...
May 15, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29760351/leptin-aggravates-reflux-esophagitis-by-increasing-tissue-levels-of-macrophage-migration-inhibitory-factor-in-rats
#18
Tsugihiro Murata, Kiyotaka Asanuma, Nobuyuki Ara, Katsunori Iijima, Waku Hatta, Shin Hamada, Naoki Asano, Tomoyuki Koike, Akira Imatani, Atsushi Masamune, Tooru Shimosegawa
Leptin, produced primarily by the adipose tissue, acts as a pro-inflammatory modulator, thereby contributing to the development of obesity-related disease. Although high levels of leptin in the obese are closely related to gastroesophageal reflux disease, the mechanism by which leptin influences esophageal inflammation remains unknown. Macrophage migration inhibitory factor (MIF) is produced by immune cells, such as T lymphocytes and macrophages, and MIF is known to induce the production of tumor necrosis factor α (TNF-α), interleukin 1β (IL-1β) and interleukin 6 (IL-6)...
2018: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/29757356/developing-a-diagnostic-understanding-of-gerd-phenotypes-through-the-analysis-of-levels-of-mucosal-injury-immune-activation-and-psychological-comorbidity
#19
C Zhong, K Liu, K Wang, H Liu, H Su, J Wu, L Duan
Patients with gastroesophageal reflux disease (GERD) can present with typical or atypical symptoms. The aim of this study is to explore the underlying physiological and psychological mechanisms that lead to different symptomatic manifestations of GERD. A total of 238 patients diagnosed with GERD underwent gastroscopy, 24 h multichannel intraluminal impedance-pH (MII-pH) monitoring, and psychological assessment with questionnaires. Patient symptoms were used to classify GERD into phenotypes of typical reflux syndrome (TRS, n = 87), reflux chest pain syndrome (RCS, n = 98), and extraesophageal syndromes (EES, n = 53)...
May 10, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29756656/pathophysiology-and-treatment-of-achalasia-in-a-muscle-mechanical-perspective
#20
REVIEW
Hans Gregersen, Kar Man Lo
This review provides a biomechanical perspective on the pathophysiology and treatment of achalasia. The esophagus is efficient in transporting ingested material to the stomach in healthy subjects. A fine balance exists between the peristaltic forces generated in the esophageal body (which herein is defined as the preload) and the resistance in the outlet, the esophago-gastric junction (which is defined as the afterload). Achalasia is a rare esophageal disease that progressively over many years challenges esophageal efficacy...
May 14, 2018: Annals of the New York Academy of Sciences
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