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https://www.readbyqxmd.com/read/29699576/ethnobotanical-investigation-on-medicinal-plants-in-algoz-area-south-kordofan-sudan
#1
Tahani Osman Issa, Yahya Sulieman Mohamed, Sakina Yagi, Reem Hassan Ahmed, Telal Mohammed Najeeb, Abdelrafie Mohamed Makhawi, Tarig Osman Khider
BACKGROUND: The inhabitants of western Sudan use traditional medicine for the treatment of various ailments due to lack of medical doctors and unaffordable prices of pharmaceutical products. The present study is the first documentation of the traditional plant knowledge on medicinal uses of plants by healers in Algoz (South Kordofan), Sudan. METHOD: Ethnobotanical data were collected over a period from March to November 2015 using semi-structured interviews with 30 healers (24 male and 6 female) living in the investigated area...
April 27, 2018: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/29628976/anti-coccidial-activity-of-the-ethanol-extract-of-tribulus-terrestris-fruits-on-eimeria-tenella
#2
Sunhwa Hong, Mi-Na Moon, Eun-Kyung Im, Jum-Soon Won, Ji-Hyun Yoo, Okjin Kim
Anti-coccidial effects of the fruits of Tribulus terrestris (Tribuli fructus) ethanol extract (TTE) were studied with animal experiment following per oral administration with Eimeria ( E .) tenella . This experiment was performed on the 3-day-old chicks (n=30). The animals were divided with 3 groups; TFE 15mg per animal+infected (n=10), TTE untreated+infected (n=10) and non-infected control (n=10). Animals were administrated with or without TTE during 1 week, and then inoculated with E. tenella . The anti-coccidial activity were evaluated with oocysts shedding numbers in stools, body weights changes and food intake changes...
March 2018: Laboratory Animal Research
https://www.readbyqxmd.com/read/29568244/herbal-medicine-for-sports-a-review
#3
REVIEW
Maha Sellami, Olfa Slimeni, Andrzej Pokrywka, Goran Kuvačić, Lawrence D Hayes, Mirjana Milic, Johnny Padulo
The use of herbal medicinal products and supplements has increased during last decades. At present, some herbs are used to enhance muscle strength and body mass. Emergent evidence suggests that the health benefits from plants are attributed to their bioactive compounds such as Polyphenols, Terpenoids, and Alkaloids which have several physiological effects on the human body. At times, manufacturers launch numerous products with banned ingredient inside with inappropriate amounts or fake supplement inducing harmful side effect...
2018: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/29505934/design-and-synthesis-of-furyl-thineyl-pyrroloquinolones-based-on-natural-alkaloid-perlolyrine-lead-to-the-discovery-of-potent-and-selective-pde5-inhibitors
#4
Hongbo Zheng, Lin Li, Bin Sun, Yun Gao, Wei Song, Xiaoyu Zhao, Yanhui Gao, Zhiyu Xie, Nianzhao Zhang, Jianbo Ji, Huiqing Yuan, Hongxiang Lou
Based on perlolyrine (1), a natural alkaloid with weak PDE5 potency from the traditional Chinese aphrodisiac plant Tribulus terrestris L., a series α-substituted tetrahydro-β-carboline (THβC) derivatives were synthesized via T+ BF4- -mediated oxidative C-H functionalization of N-aryl THβCs with diverse potassium trifluoroborates. Following Winterfeldt oxidation afforded the corresponding furyl/thienyl pyrroloquinolones, of which 5-ethylthiophene/ethylfuran derivatives 20a-b were identified as the most potent and selective PDE5 inhibitors...
April 25, 2018: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29261340/role-of-tribulus-terrestris-in-male-infertility-is-it-real-or-fiction
#5
Sameh Fayek GamalEl Din
Tribulus terrestris is an annual herb of the Zygophyllaceae family and is commonly known as Gokshur, Gokharu, or puncturevine. Flavonoids, alkaloids, saponins, lignin, amides, and glycosides are the main active phytoconstituents of this plant. Infertility is defined by the failure to conceive a child after one year or more of regular unprotected sexual intercourse. Infertility affects society at large and has a negative impact on the social and emotional aspects of the patient. This in-depth review presents several studies that evaluate the role of Tribulus terrestris in a chronological order to help us better understand the exact mechanism by which this herbal medicine acts in male infertility...
December 20, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/29177586/phenolic-amides-from-tribulus-terrestris-and-their-inhibitory-effects-on-nitric-oxide-production-in-raw-264-7-cells
#6
Hyung Sik Kim, Jin Woo Lee, Hari Jang, Thi Phuong Linh Le, Jun Gu Kim, Moon Soon Lee, Jin Tae Hong, Mi Kyeong Lee, Bang Yeon Hwang
A new phenolic amide, named cis-terrestriamide (7), together with ten known compounds (1-6, 8-11), were isolated from the methanolic extract of the fruits of Tribulus terrestris. The structure of 7 was elucidated on the basis of extensive analyses of 1D and 2D nuclear magnetic resonance spectroscopic and high resolution mass spectrometry data. Compounds 1, 2, 5, 6, 8, 9, and 11 exhibited inhibitory effects on the lipopolysaccharide-stimulated nitric oxide production in RAW 264.7 cells, with IC50 values of 18...
February 2018: Archives of Pharmacal Research
https://www.readbyqxmd.com/read/29172782/efficacy-of-tribulus-terrestris-for-the-treatment-of-premenopausal-women-with-hypoactive-sexual-desire-disorder-a-randomized-double-blinded-placebo-controlled-trial
#7
Fabiene Bernardes Castro Vale, Karla Zanolla Dias de Souza, Camilla Russi Rezende, Selmo Geber
Although hypoactive sexual desire disorder (HSDD) is the most common sexual complaint, there is no consensus for the ideal treatment. Our study aimed to evaluate the efficacy of treating premenopausal women with HSDD with Tribulus terrestris and its effect on the serum levels of testosterone. We performed a prospective, randomized, double-blind, placebo-controlled trial, with 40 premenopausal women reporting diminished libido, receiving T. terrestris or placebo. The questionnaires FSFI and the QS-F were used to evaluate sexual dysfunction before and after treatment...
November 27, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29052328/increased-sperm-cell-production-in-ageing-roosters-by-an-oral-treatment-with-an-aromatase-inhibitor-and-a-natural-herbal-extract-designed-for-improving-fertility
#8
H Adeldust, A Farzinpour, A Farshad, J Rostamzadeh, M Lopez-Bejar
Rooster fertility peaks between 30 and 40 weeks of age and declines rapidly from 50 weeks of age. This is linked to a reduction in the number of spermatozoa in the ejaculate due to high density of spermatids in the seminiferous tubules of low-fertility roosters. In this study, we assessed the effects over spermatogenesis of both letrozole, an aromatase inhibitor, and a commercial herbal extract designed for improving fertility composed by Tribulus, Cinnamomum, Zingiber and Sativus. Forty-two-week-old Ross 308 roosters (n = 24) were distributed into four groups: control, letrozole (0...
October 2017: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/28939023/vascular-protective-effects-of-aqueous-extracts-of-tribulus-terrestris-on-hypertensive-endothelial-injury
#9
Yue-Hua Jiang, Jin-Hao Guo, Sai Wu, Chuan-Hua Yang
Angiotensin II (Ang II) is involved in endothelium injury during the development of hypertension. Tribulus terrestris (TT) is used to treat hypertension, arteriosclerosis, and post-stroke syndrome in China. The present study aimed to determine the effects of aqueous TT extracts on endothelial injury in spontaneously hypertensive rats (SHRs) and its protective effects against Ang II-induced injury in human umbilical vein endothelial cells (HUVECs). SHRs were administered intragastrically with TT (17.2 or 8.6 g·kg-1·d-1) for 6 weeks, using valsartan (13...
August 2017: Chinese Journal of Natural Medicines
https://www.readbyqxmd.com/read/28846699/response-surface-methodology-based-extraction-of-tribulus-terrestris-leads-to-an-upsurge-of-antilithiatic-potential-by-inhibition-of-calcium-oxalate-crystallization-processes
#10
Jyoti Kaushik, Simran Tandon, Varun Gupta, Jasamrit Nayyar, Surinder Kumar Singla, Chanderdeep Tandon
Tribulus terrestris has significant antilithiatic efficacy established via both in vitro as well as in vivo studies and is used in numerous anti-urolithiatic herbal formulations viz. Cystone, Uriflow, Uritone and Neeri. However, to fully utilize its antilithiatic potential, the influence of different extraction parameters on antilithiatic ability of T. terrestris aqueous extract needs elucidation. Thus, the current study was undertaken using statistically optimized extraction conditions for aqueous extract preparation...
2017: PloS One
https://www.readbyqxmd.com/read/28766114/rapid-characterization-of-constituents-in-tribulus-terrestris-from-different-habitats-by-uhplc-q-tof-ms
#11
Wei Zheng, Fangxu Wang, Yang Zhao, Xinguang Sun, Liping Kang, Ziquan Fan, Lirui Qiao, Renyi Yan, Shuchen Liu, Baiping Ma
A strategy for rapid identification of the chemical constituents from crude extracts of Tribulus terrestris was proposed using an informatics platform for the UHPLC/Q-TOF MS(E) data analyses. This strategy mainly utilizes neutral losses, characteristic fragments, and in-house library to rapidly identify the structure of the compounds. With this strategy, rapid characterization of the chemical components of T. terrestris from Beijing, China was successfully achieved. A total of 82 steroidal saponins and nine flavonoids were identified or tentatively identified from T...
November 2017: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/28755953/kidney-toxicity-related-to-herbs-and-dietary-supplements-online-table-of-case-reports-part-3-of-5-series
#12
REVIEW
Amy Christine Brown
BACKGROUND: No tabular summary of potentially life-threatening, kidney-toxic dietary supplements (DS; includes herbs) based on PubMed case reports is currently available online and continually updated to forewarn United States consumers, clinicians, and companies manufacturing DS. The purpose of this review was to create an online research summary table of kidney toxicity case reports related to DS. METHODS: Documented PubMed case reports (1966 to May 2016, and cross-referencing) of DS appearing to contribute to kidney toxicity were listed in "DS Toxic Tables...
September 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28748172/protective-effect-of-tribulus-terrestris-fruit-extract-on-cerulein-induced-acute-pancreatitis-in-mice
#13
Mina Borran, Mohsen Minaiyan, Behzad Zolfaghari, Parvin Mahzouni
OBJECTIVE: Antioxidant, anti-inflammatory, analgesic and antimicrobial activities of Tribulus terrestris (T. terrestris) could be helpful in the treatment of acute pancreatitis; thus, this study was designed to investigate the effects of T. terrestris on cerulein-induced acute pancreatitis in mice. MATERIALS AND METHODS: Three doses (100, 200 and 400 mg/kg) of T. terrestris hydro-alcoholic extract were administered both orally (60 minutes before pancreatitis induction, p...
May 2017: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/28685911/combined-lifestyle-and-herbal-medicine-in-overweight-women-with-polycystic-ovary-syndrome-pcos-a-randomized-controlled-trial
#14
Susan Arentz, Caroline A Smith, Jason Abbott, Paul Fahey, Birinder S Cheema, Alan Bensoussan
Polycystic ovary syndrome (PCOS) is a common, complex reproductive endocrinopathy characterized by menstrual irregularities, hyperandrogenism and polycystic ovaries. Lifestyle modification is a first-line intervention; however, there are barriers to success for this form of self-care, and women often seek adjunct therapies including herbal medicines. This pragmatic, randomized controlled trial, delivered in communities of Australia in overweight women with PCOS, compared the effectiveness and safety of a lifestyle intervention plus herbal medicine against lifestyle alone...
September 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28685547/in-vitro-antioxidant-potential-of-selected-aphrodisiac-medicinal-plants
#15
M Riaz, M Shahid, A Jamil, M Saqib
The present study aimed to evaluate the antioxidant activity of six selected aphrodisiac medicinal plants. Useful parts of the selected medicinal plants were collected and extracted in methanolic solvent. The antioxidant activity of selected plant extract was determined through different antioxidant assays, namely DPPH radical scavenging assay and ferric reducing antioxidant assay. Moreover, antioxidant compounds, like total phenolics and total flavonoids contents, were also determined. Results showed that Mucuna pruriens seed extract displayed high contents of phenolic compounds with total phenolic content of 683...
April 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28677770/the-function-of-androgen-androgen-receptor-and-insulin-growth-factor%C3%A2-1-insulin-growth-factor%C3%A2-1-receptor-on-the-effects-of-tribulus%C3%A2-terrestris-extracts-in-rats-undergoing-high-intensity-exercise
#16
Yin Wu, Hongfang Yang, Xiaohui Wang
Our previous study demonstrated that treatment with Tribulus terrestris (TT) extracts (120 mg/kg) promoted the muscle weight gain and performance of rats undergoing high intensity exercise. The present study was designed to explore the mechanisms underlying the effect of treatment with TT extracts and the involvement of androgens, the androgen receptor (AR), insulin growth factor‑1 (IGF‑1) and the IGF‑1 receptor (IGF‑1R). A total of 32 Sprague‑Dawley rats were randomly divided into groups as follows: Control; TT, treated with TT extracts, E, high intensity exercise; E+TT, high intensity exercise plus TT treatment...
September 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28595608/antimicrobial-activity-toxicity-and-anti-inflammatory-potential-of-methanolic-extracts-of-four-ethnomedicinal-plant-species-from-punjab-pakistan
#17
Rabia Naz, Hafsa Ayub, Sajid Nawaz, Zia Ul Islam, Tayyaba Yasmin, Asghari Bano, Abdul Wakeel, Saqib Zia, Thomas H Roberts
BACKGROUND: The plant species Aristolochia indica (AI), Melilotus indicus (MI), Tribulus terrestris (TT) and Cuscuta pedicellata (CP) are widely used in folk medicine in the villages around Chowk Azam, South Punjab, Pakistan. The aim of this study was to evaluate the antioxidant activity, phytochemical composition, and the antibacterial, antifungal, cytotoxic and anti-inflammatory potential of the four medicinal plants listed above. For CP stem, this study represents (to the best of our knowledge) the first time phytochemicals have been identified and the antioxidant and anti-inflammatory potential determined...
June 8, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28546803/effect-of-tribulus-terrestris-ginger-saffron-and-cinnamomum-on-menopausal-symptoms-a-randomised-placebo-controlled-clinical-trial
#18
Simin Taavoni, Neda Nazem Ekbatani, Hamid Haghani
Menopausal symptoms experienced by women vary widely, and while many women transition through menopause with manageable symptoms, others experience severe symptoms, which may impair their quality of life. The purpose of this study was to determine the effect of Tribulus terrestris, ginger, saffron, and Cinnamomum on menopausal symptoms. A randomised, triple-blind, controlled trial design was used for this study. The participants were 80 postmenopausal women aged 50-60 years. A demographic data form and the Menopause Rating Scale were used to collect data...
March 2017: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/28462131/effect-of-combination-of-withania-somnifera-dunal-and-tribulus-terrestris-linn-on-letrozole-induced-polycystic-ovarian-syndrome-in-rats
#19
Amrin Saiyed, Nasreen Jahan, Shaikh Ajij Ahmed Makbul, Mushir Ansari, Humaira Bano, Syeda Hajera Habib
BACKGROUND: To investigate the effect of the combination of hydroalcoholic extract of Withania somnifera (WS) and Tribulus terrestris (TT) on letrozole induced polycystic ovarian syndrome (PCOS) in rat. METHODS: Twenty four female Wistar rats of regular estrus cycle were divided into four groups of six animals each. The negative control group received 1 mL of 0.5% carboxy methyl cellulose. The animals of the other groups were treated with letrozole (1 mg/kg) for 21 days for induction of PCOS...
December 2016: Integrative Medicine Research
https://www.readbyqxmd.com/read/28364864/evaluation-of-the-efficacy-and-safety-of-tribulus-terrestris-in-male-sexual-dysfunction-a-prospective-randomized-double-blind-placebo-controlled-clinical-trial
#20
RANDOMIZED CONTROLLED TRIAL
Zdravko Kamenov, Svetlana Fileva, Krassimir Kalinov, Emmanuele A Jannini
OBJECTIVE: The primary objectives were to compare the efficacy of extracts of the plant Tribulus terrestris (TT; marketed as Tribestan), in comparison with placebo, for the treatment of men with erectile dysfunction (ED) and with or without hypoactive sexual desire disorder (HSDD), as well as to monitor the safety profile of the drug. The secondary objective was to evaluate the level of lipids in blood during treatment. PARTICIPANTS AND DESIGN: Phase IV, prospective, randomized, double-blind, placebo-controlled clinical trial in parallel groups...
May 2017: Maturitas
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