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https://www.readbyqxmd.com/read/27886180/microrna-regulation-of-endothelial-trex1-reprograms-the-tumour-microenvironment
#1
RaeAnna Wilson, Cristina Espinosa-Diez, Nathan Kanner, Namita Chatterjee, Rebecca Ruhl, Christina Hipfinger, Sunil J Advani, Jie Li, Omar F Khan, Aleksandra Franovic, Sara M Weis, Sushil Kumar, Lisa M Coussens, Daniel G Anderson, Clark C Chen, David A Cheresh, Sudarshan Anand
Rather than targeting tumour cells directly, elements of the tumour microenvironment can be modulated to sensitize tumours to the effects of therapy. Here we report a unique mechanism by which ectopic microRNA-103 can manipulate tumour-associated endothelial cells to enhance tumour cell death. Using gain-and-loss of function approaches, we show that miR-103 exacerbates DNA damage and inhibits angiogenesis in vitro and in vivo. Local, systemic or vascular-targeted delivery of miR-103 in tumour-bearing mice decreased angiogenesis and tumour growth...
November 25, 2016: Nature Communications
https://www.readbyqxmd.com/read/27884642/psychiatric-comorbidities-in-epilepsy-should-they-be-considered-in-the-classification-of-epileptic-disorders
#2
Andres M Kanner
The prevalence of psychiatric comorbidities is relatively high in people with epilepsy (PWE), as one in three patients will have experienced a psychiatric disorder in the course of their life. The new definition of epilepsy recognizes these comorbidities as part of the seizure disorder, which need to be recognized and treated together with the actual epileptic seizures. Psychiatric comorbidities have a complex relation with epilepsy, being associated with a negative course of the seizure disorder, worse tolerance of pharmacotherapy with AEDs, development of iatrogenic psychiatric complications from pharmacologic and surgical treatments, and increased mortality risks...
November 21, 2016: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/27669633/aging-with-autism-spectrum-disorder-an-emerging-public-health-problem
#3
Ana Hategan, James A Bourgeois, Jeremy Goldberg
From 1943, when Leo Kanner originally described autism, and to the first objective criteria for "infantile autism" in DSM-III and the inclusion of Asperger's disorder in DSM-IV, the subsequent classification scheme for autistic disorders has led to a substantial change with the 2013 issuance of the DSM-5 by including subcategories into one umbrella diagnosis of autism spectrum disorder (ASD) (Baker, 2013). ASD is a lifelong neurodevelopmental disorder, characterized by social and communication impairments and restricted, stereotypical patterns of behavior (Baker, 2013)...
September 27, 2016: International Psychogeriatrics
https://www.readbyqxmd.com/read/27651455/phosphorylation-specific-status-of-rnai-triggers-in-pharmacokinetic-and-biodistribution-analyses
#4
Vladimir S Trubetskoy, Jacob B Griffin, Anthony L Nicholas, Eric M Nord, Zhao Xu, Ryan M Peterson, Christine I Wooddell, David B Rozema, Darren H Wakefield, David L Lewis, Steven B Kanner
The RNA interference (RNAi)-based therapeutic ARC-520 for chronic hepatitis B virus (HBV) infection consists of a melittin-derived peptide conjugated to N-acetylgalactosamine for hepatocyte targeting and endosomal escape, and cholesterol-conjugated RNAi triggers, which together result in HBV gene silencing. To characterize the kinetics of RNAi trigger delivery and 5'-phosphorylation of guide strands correlating with gene knockdown, we employed a peptide-nucleic acid (PNA) hybridization assay. A fluorescent sense strand PNA probe binding to RNAi duplex guide strands was coupled with anion exchange high performance liquid chromatography to quantitate guide strands and metabolites...
September 19, 2016: Nucleic Acids Research
https://www.readbyqxmd.com/read/27624646/kanner-asperger-and-frankl-a-third-man-at-the-genesis-of-the-autism-diagnosis
#5
John E Robison
Scholars have long speculated about how Kanner and Asperger's descriptions of autistic behavior appeared just 1 year apart in America and Austria even as World War II had severed communication between the two countries. Both conspiracy and serendipity have been alleged, but a simpler explanation has now emerged. Autistic knowledge crossed the Atlantic with Georg Frankl-a previously unrecognized "man in the middle" who followed his fiancé to America. The evidence presented here fills in many blanks and suggests both Kanner and Asperger benefited from Frankl's insight...
September 13, 2016: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/27579823/biomarkers-predictive-of-exacerbations-in-the-spiromics-and-copdgene-cohorts
#6
Jason D Keene, Sean Jacobson, Katerina Kechris, Gregory L Kinney, Marilyn G Foreman, Claire M Doerschuk, Barry J Make, Jeffrey L Curtis, Stephen I Rennard, R Graham Barr, Eugene R Bleecker, Richard E Kanner, Eric C Kleerup, Nadia N Hansel, Prescott G Woodruff, MeiLan K Han, Robert Paine Iii, Fernando J Martinez, Russell P Bowler, Wanda K O'Neal
RATIONALE: COPD exacerbations are associated with disease progression, higher healthcare cost, and increased mortality. Published predictors of future exacerbations include previous exacerbation, airflow obstruction, poor overall health, home oxygen use, and gastroesophageal reflux. The value of adding blood biomarkers to clinical variables to predict exacerbations remains unproven. METHODS: Subjects from SPIROMICS (n=1544) and COPDGene (n=602) cohorts had 90 plasma or serum candidate proteins measured on study entry using Myriad-RBM multiplex panels...
August 31, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27564413/age-and-small-airway-imaging-abnormalities-in-subjects-with-and-without-airflow-obstruction-in-spiromics
#7
Carlos H Martinez, Alejandro A Diaz, Catherine Meldrum, Jeffrey L Curtis, Christopher B Cooper, Cheryl Pirozzi, Richard E Kanner, Robert Paine Iii, Prescott G Woodruff, Eugene R Bleecker, Nadia N Hansel, R Graham Barr, Nathaniel Marchetti, Gerard J Criner, Ella A Kazerooni, Eric A Hoffman, Brian D Ross, Craig J Galban, Christine T Cigolle, Fernando J Martinez, MeiLan K Han
RATIONALE: Aging is associated with reduced forced expiratory volume in the first second (FEV1) to forced vital capacity (FVC) ratio (FEV1/FVC), hyperinflation and alveolar enlargement, but little is known about how age affects small airways. We hypothesized that chest computed tomography(CT)-assessed functional small airway would increase with age, even among asymptomatic individuals. METHODS: We used parametric response mapping analysis of paired inspiratory/expiratory CTs to identify functional small airway abnormality (PRMFSA) and emphysema (PRMEMPH) in the SPIROMICS cohort...
August 26, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27544484/astrocytes-from-old-alzheimer-s-disease-mice-are-impaired-in-a%C3%AE-uptake-and-in-neuroprotection
#8
Tal Iram, Dorit Trudler, David Kain, Sivan Kanner, Ronit Galron, Robert Vassar, Ari Barzilai, Pablo Blinder, Zvi Fishelson, Dan Frenkel
In Alzheimer's disease (AD), astrocytes undergo morphological changes ranging from atrophy to hypertrophy, but the effect of such changes at the functional level is still largely unknown. Here, we aimed to investigate whether alterations in astrocyte activity in AD are transient and depend on their microenvironment, or whether they are irreversible. We established and characterized a new protocol for the isolation of adult astrocytes and discovered that astrocytes isolated from old 5xFAD mice have higher GFAP expression than astrocytes derived from WT mice, as observed in vivo...
August 17, 2016: Neurobiology of Disease
https://www.readbyqxmd.com/read/27532455/common-genetic-polymorphisms-influence-blood-biomarker-measurements-in-copd
#9
Wei Sun, Katerina Kechris, Sean Jacobson, M Bradley Drummond, Gregory A Hawkins, Jenny Yang, Ting-Huei Chen, Pedro Miguel Quibrera, Wayne Anderson, R Graham Barr, Patricia V Basta, Eugene R Bleecker, Terri Beaty, Richard Casaburi, Peter Castaldi, Michael H Cho, Alejandro Comellas, James D Crapo, Gerard Criner, Dawn Demeo, Stephanie A Christenson, David J Couper, Jeffrey L Curtis, Claire M Doerschuk, Christine M Freeman, Natalia A Gouskova, MeiLan K Han, Nicola A Hanania, Nadia N Hansel, Craig P Hersh, Eric A Hoffman, Robert J Kaner, Richard E Kanner, Eric C Kleerup, Sharon Lutz, Fernando J Martinez, Deborah A Meyers, Stephen P Peters, Elizabeth A Regan, Stephen I Rennard, Mary Beth Scholand, Edwin K Silverman, Prescott G Woodruff, Wanda K O'Neal, Russell P Bowler
Implementing precision medicine for complex diseases such as chronic obstructive lung disease (COPD) will require extensive use of biomarkers and an in-depth understanding of how genetic, epigenetic, and environmental variations contribute to phenotypic diversity and disease progression. A meta-analysis from two large cohorts of current and former smokers with and without COPD [SPIROMICS (N = 750); COPDGene (N = 590)] was used to identify single nucleotide polymorphisms (SNPs) associated with measurement of 88 blood proteins (protein quantitative trait loci; pQTLs)...
August 2016: PLoS Genetics
https://www.readbyqxmd.com/read/27492391/klippel-tr%C3%A3-naunay-syndrome-need-for-careful-clinical-classification
#10
Kevin R Volz, Christopher D Kanner, Julie Evans, Kevin D Evans
Klippel-Trénaunay syndrome (KTS) is a rare congenital malformation characterized by a triad of clinical presentations: (1) capillary malformations manifesting as a "port wine stain"; (2) limb hypertrophy; and (3) venous varicosities. It is distinguished from Parkes-Weber syndrome by the absence of substantial arteriovenous shunting. Due to the clinical implications of an arteriovenous fistula, differentiation between the two syndromes is important, as the prognosis and treatment greatly differ. We present a series of 5 cases of suspected KTS, while emphasizing the difficulties in distinguishing KTS from Parkes-Weber syndrome without diagnostic imaging and underscoring the importance of accurately classifying patients with the appropriate syndrome...
September 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/27464262/long-term-evolution-of-multiple-sclerosis-disability-in-the-treatment-era
#11
Bruce A C Cree, Pierre-Antoine Gourraud, Jorge R Oksenberg, Carolyn Bevan, Elizabeth Crabtree-Hartman, Jeffrey M Gelfand, Douglas S Goodin, Jennifer Graves, Ari J Green, Ellen Mowry, Darin T Okuda, Daniel Pelletier, H-Christian von Büdingen, Scott S Zamvil, Alisha Agrawal, Stacy Caillier, Caroline Ciocca, Refujia Gomez, Rachel Kanner, Robin Lincoln, Antoine Lizee, Pamela Qualley, Adam Santaniello, Leena Suleiman, Monica Bucci, Valentina Panara, Nico Papinutto, William A Stern, Alyssa H Zhu, Gary R Cutter, Sergio Baranzini, Roland G Henry, Stephen L Hauser
OBJECTIVE: To characterize the accrual of long-term disability in a cohort of actively treated multiple sclerosis (MS) patients and to assess whether clinical and magnetic resonance imaging (MRI) data used in clinical trials have long-term prognostic value. METHODS: This is a prospective study of 517 actively managed MS patients enrolled at a single center. RESULTS: More than 91% of patients were retained, with data ascertained up to 10 years after the baseline visit...
October 2016: Annals of Neurology
https://www.readbyqxmd.com/read/27390321/early-biomarkers-from-conventional-and-delayed-contrast-mri-to-predict-the-response-to-bevacizumab-in-recurrent-high-grade-gliomas
#12
D Daniels, D Guez, D Last, C Hoffmann, D Nass, A Talianski, G Tsarfaty, S Salomon, A A Kanner, D T Blumenthal, F Bokstein, S Harnof, D Yekutieli, S Zamir, Z R Cohen, L Zach, Y Mardor
BACKGROUND AND PURPOSE: The interpretation of the radiologic response of bevacizumab-treated patients with recurrent high-grade gliomas represents a unique challenge. Delayed-contrast MR imaging was recently introduced for calculating treatment-response-assessment maps in patients with brain tumors, providing clear separation between active tumor and treatment effects. We studied the application of standard and delayed-contrast MR imaging for assessing and predicting the response to bevacizumab...
July 7, 2016: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/27373129/coexistent-trichilemmoma-and-trichoblastoma-without-associated-nevus-sebaceus
#13
A M Stowman, M M Griffin, W A Kanner, G Tchernev, A A Chokoeva, U Wollina, T Lotti, M Fioranelli, M G Roccia, G K Maximov, J W Patterson
Trichilemmoma and trichoblastoma are benign adnexal neoplasms derived from the hair follicle unit. While trichilemmomas are closely associated with the epidermis, trichoblastomas are found within the dermis and subcutaneous tissue. Both tumors have been reported to arise within nevus sebaceus of Jadassohn (NSJ). We present a 42-year-old white male with a 5 mm crusted, erythematous papule on the right occipital scalp that had been present for years. A shave biopsy was performed and read as trichilemmoma involving the biopsy base...
April 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/27367379/gw151226-observation-of-gravitational-waves-from-a-22-solar-mass-binary-black-hole-coalescence
#14
B P Abbott, R Abbott, T D Abbott, M R Abernathy, F Acernese, K Ackley, C Adams, T Adams, P Addesso, R X Adhikari, V B Adya, C Affeldt, M Agathos, K Agatsuma, N Aggarwal, O D Aguiar, L Aiello, A Ain, P Ajith, B Allen, A Allocca, P A Altin, S B Anderson, W G Anderson, K Arai, M C Araya, C C Arceneaux, J S Areeda, N Arnaud, K G Arun, S Ascenzi, G Ashton, M Ast, S M Aston, P Astone, P Aufmuth, C Aulbert, S Babak, P Bacon, M K M Bader, P T Baker, F Baldaccini, G Ballardin, S W Ballmer, J C Barayoga, S E Barclay, B C Barish, D Barker, F Barone, B Barr, L Barsotti, M Barsuglia, D Barta, J Bartlett, I Bartos, R Bassiri, A Basti, J C Batch, C Baune, V Bavigadda, M Bazzan, M Bejger, A S Bell, B K Berger, G Bergmann, C P L Berry, D Bersanetti, A Bertolini, J Betzwieser, S Bhagwat, R Bhandare, I A Bilenko, G Billingsley, J Birch, R Birney, O Birnholtz, S Biscans, A Bisht, M Bitossi, C Biwer, M A Bizouard, J K Blackburn, C D Blair, D G Blair, R M Blair, S Bloemen, O Bock, M Boer, G Bogaert, C Bogan, A Bohe, C Bond, F Bondu, R Bonnand, B A Boom, R Bork, V Boschi, S Bose, Y Bouffanais, A Bozzi, C Bradaschia, P R Brady, V B Braginsky, M Branchesi, J E Brau, T Briant, A Brillet, M Brinkmann, V Brisson, P Brockill, J E Broida, A F Brooks, D A Brown, D D Brown, N M Brown, S Brunett, C C Buchanan, A Buikema, T Bulik, H J Bulten, A Buonanno, D Buskulic, C Buy, R L Byer, M Cabero, L Cadonati, G Cagnoli, C Cahillane, J Calderón Bustillo, T Callister, E Calloni, J B Camp, K C Cannon, J Cao, C D Capano, E Capocasa, F Carbognani, S Caride, J Casanueva Diaz, C Casentini, S Caudill, M Cavaglià, F Cavalier, R Cavalieri, G Cella, C B Cepeda, L Cerboni Baiardi, G Cerretani, E Cesarini, S J Chamberlin, M Chan, S Chao, P Charlton, E Chassande-Mottin, B D Cheeseboro, H Y Chen, Y Chen, C Cheng, A Chincarini, A Chiummo, H S Cho, M Cho, J H Chow, N Christensen, Q Chu, S Chua, S Chung, G Ciani, F Clara, J A Clark, F Cleva, E Coccia, P-F Cohadon, A Colla, C G Collette, L Cominsky, M Constancio, A Conte, L Conti, D Cook, T R Corbitt, N Cornish, A Corsi, S Cortese, C A Costa, M W Coughlin, S B Coughlin, J-P Coulon, S T Countryman, P Couvares, E E Cowan, D M Coward, M J Cowart, D C Coyne, R Coyne, K Craig, J D E Creighton, J Cripe, S G Crowder, A Cumming, L Cunningham, E Cuoco, T Dal Canton, S L Danilishin, S D'Antonio, K Danzmann, N S Darman, A Dasgupta, C F Da Silva Costa, V Dattilo, I Dave, M Davier, G S Davies, E J Daw, R Day, S De, D DeBra, G Debreczeni, J Degallaix, M De Laurentis, S Deléglise, W Del Pozzo, T Denker, T Dent, V Dergachev, R De Rosa, R T DeRosa, R DeSalvo, R C Devine, S Dhurandhar, M C Díaz, L Di Fiore, M Di Giovanni, T Di Girolamo, A Di Lieto, S Di Pace, I Di Palma, A Di Virgilio, V Dolique, F Donovan, K L Dooley, S Doravari, R Douglas, T P Downes, M Drago, R W P Drever, J C Driggers, M Ducrot, S E Dwyer, T B Edo, M C Edwards, A Effler, H-B Eggenstein, P Ehrens, J Eichholz, S S Eikenberry, W Engels, R C Essick, T Etzel, M Evans, T M Evans, R Everett, M Factourovich, V Fafone, H Fair, S Fairhurst, X Fan, Q Fang, S Farinon, B Farr, W M Farr, M Favata, M Fays, H Fehrmann, M M Fejer, E Fenyvesi, I Ferrante, E C Ferreira, F Ferrini, F Fidecaro, I Fiori, D Fiorucci, R P Fisher, R Flaminio, M Fletcher, H Fong, J-D Fournier, S Frasca, F Frasconi, Z Frei, A Freise, R Frey, V Frey, P Fritschel, V V Frolov, P Fulda, M Fyffe, H A G Gabbard, J R Gair, L Gammaitoni, S G Gaonkar, F Garufi, G Gaur, N Gehrels, G Gemme, P Geng, E Genin, A Gennai, J George, L Gergely, V Germain, Abhirup Ghosh, Archisman Ghosh, S Ghosh, J A Giaime, K D Giardina, A Giazotto, K Gill, A Glaefke, E Goetz, R Goetz, L Gondan, G González, J M Gonzalez Castro, A Gopakumar, N A Gordon, M L Gorodetsky, S E Gossan, M Gosselin, R Gouaty, A Grado, C Graef, P B Graff, M Granata, A Grant, S Gras, C Gray, G Greco, A C Green, P Groot, H Grote, S Grunewald, G M Guidi, X Guo, A Gupta, M K Gupta, K E Gushwa, E K Gustafson, R Gustafson, J J Hacker, B R Hall, E D Hall, H Hamilton, G Hammond, M Haney, M M Hanke, J Hanks, C Hanna, M D Hannam, J Hanson, T Hardwick, J Harms, G M Harry, I W Harry, M J Hart, M T Hartman, C-J Haster, K Haughian, J Healy, A Heidmann, M C Heintze, H Heitmann, P Hello, G Hemming, M Hendry, I S Heng, J Hennig, J Henry, A W Heptonstall, M Heurs, S Hild, D Hoak, D Hofman, K Holt, D E Holz, P Hopkins, J Hough, E A Houston, E J Howell, Y M Hu, S Huang, E A Huerta, D Huet, B Hughey, S Husa, S H Huttner, T Huynh-Dinh, N Indik, D R Ingram, R Inta, H N Isa, J-M Isac, M Isi, T Isogai, B R Iyer, K Izumi, T Jacqmin, H Jang, K Jani, P Jaranowski, S Jawahar, L Jian, F Jiménez-Forteza, W W Johnson, N K Johnson-McDaniel, D I Jones, R Jones, R J G Jonker, L Ju, Haris K, C V Kalaghatgi, V Kalogera, S Kandhasamy, G Kang, J B Kanner, S J Kapadia, S Karki, K S Karvinen, M Kasprzack, E Katsavounidis, W Katzman, S Kaufer, T Kaur, K Kawabe, F Kéfélian, M S Kehl, D Keitel, D B Kelley, W Kells, R Kennedy, J S Key, F Y Khalili, I Khan, S Khan, Z Khan, E A Khazanov, N Kijbunchoo, Chi-Woong Kim, Chunglee Kim, J Kim, K Kim, N Kim, W Kim, Y-M Kim, S J Kimbrell, E J King, P J King, J S Kissel, B Klein, L Kleybolte, S Klimenko, S M Koehlenbeck, S Koley, V Kondrashov, A Kontos, M Korobko, W Z Korth, I Kowalska, D B Kozak, V Kringel, B Krishnan, A Królak, C Krueger, G Kuehn, P Kumar, R Kumar, L Kuo, A Kutynia, B D Lackey, M Landry, J Lange, B Lantz, P D Lasky, M Laxen, A Lazzarini, C Lazzaro, P Leaci, S Leavey, E O Lebigot, C H Lee, H K Lee, H M Lee, K Lee, A Lenon, M Leonardi, J R Leong, N Leroy, N Letendre, Y Levin, J B Lewis, T G F Li, A Libson, T B Littenberg, N A Lockerbie, A L Lombardi, L T London, J E Lord, M Lorenzini, V Loriette, M Lormand, G Losurdo, J D Lough, C O Lousto, H Lück, A P Lundgren, R Lynch, Y Ma, B Machenschalk, M MacInnis, D M Macleod, F Magaña-Sandoval, L Magaña Zertuche, R M Magee, E Majorana, I Maksimovic, V Malvezzi, N Man, I Mandel, V Mandic, V Mangano, G L Mansell, M Manske, M Mantovani, F Marchesoni, F Marion, S Márka, Z Márka, A S Markosyan, E Maros, F Martelli, L Martellini, I W Martin, D V Martynov, J N Marx, K Mason, A Masserot, T J Massinger, M Masso-Reid, S Mastrogiovanni, F Matichard, L Matone, N Mavalvala, N Mazumder, R McCarthy, D E McClelland, S McCormick, S C McGuire, G McIntyre, J McIver, D J McManus, T McRae, S T McWilliams, D Meacher, G D Meadors, J Meidam, A Melatos, G Mendell, R A Mercer, E L Merilh, M Merzougui, S Meshkov, C Messenger, C Messick, R Metzdorff, P M Meyers, F Mezzani, H Miao, C Michel, H Middleton, E E Mikhailov, L Milano, A L Miller, A Miller, B B Miller, J Miller, M Millhouse, Y Minenkov, J Ming, S Mirshekari, C Mishra, S Mitra, V P Mitrofanov, G Mitselmakher, R Mittleman, A Moggi, M Mohan, S R P Mohapatra, M Montani, B C Moore, C J Moore, D Moraru, G Moreno, S R Morriss, K Mossavi, B Mours, C M Mow-Lowry, G Mueller, A W Muir, Arunava Mukherjee, D Mukherjee, S Mukherjee, N Mukund, A Mullavey, J Munch, D J Murphy, P G Murray, A Mytidis, I Nardecchia, L Naticchioni, R K Nayak, K Nedkova, G Nelemans, T J N Nelson, M Neri, A Neunzert, G Newton, T T Nguyen, A B Nielsen, S Nissanke, A Nitz, F Nocera, D Nolting, M E N Normandin, L K Nuttall, J Oberling, E Ochsner, J O'Dell, E Oelker, G H Ogin, J J Oh, S H Oh, F Ohme, M Oliver, P Oppermann, Richard J Oram, B O'Reilly, R O'Shaughnessy, D J Ottaway, H Overmier, B J Owen, A Pai, S A Pai, J R Palamos, O Palashov, C Palomba, A Pal-Singh, H Pan, C Pankow, F Pannarale, B C Pant, F Paoletti, A Paoli, M A Papa, H R Paris, W Parker, D Pascucci, A Pasqualetti, R Passaquieti, D Passuello, B Patricelli, Z Patrick, B L Pearlstone, M Pedraza, R Pedurand, L Pekowsky, A Pele, S Penn, A Perreca, L M Perri, H P Pfeiffer, M Phelps, O J Piccinni, M Pichot, F Piergiovanni, V Pierro, G Pillant, L Pinard, I M Pinto, M Pitkin, M Poe, R Poggiani, P Popolizio, A Post, J Powell, J Prasad, V Predoi, T Prestegard, L R Price, M Prijatelj, M Principe, S Privitera, R Prix, G A Prodi, L Prokhorov, O Puncken, M Punturo, P Puppo, M Pürrer, H Qi, J Qin, S Qiu, V Quetschke, E A Quintero, R Quitzow-James, F J Raab, D S Rabeling, H Radkins, P Raffai, S Raja, C Rajan, M Rakhmanov, P Rapagnani, V Raymond, M Razzano, V Re, J Read, C M Reed, T Regimbau, L Rei, S Reid, D H Reitze, H Rew, S D Reyes, F Ricci, K Riles, M Rizzo, N A Robertson, R Robie, F Robinet, A Rocchi, L Rolland, J G Rollins, V J Roma, J D Romano, R Romano, G Romanov, J H Romie, D Rosińska, S Rowan, A Rüdiger, P Ruggi, K Ryan, S Sachdev, T Sadecki, L Sadeghian, M Sakellariadou, L Salconi, M Saleem, F Salemi, A Samajdar, L Sammut, E J Sanchez, V Sandberg, B Sandeen, J R Sanders, B Sassolas, B S Sathyaprakash, P R Saulson, O E S Sauter, R L Savage, A Sawadsky, P Schale, R Schilling, J Schmidt, P Schmidt, R Schnabel, R M S Schofield, A Schönbeck, E Schreiber, D Schuette, B F Schutz, J Scott, S M Scott, D Sellers, A S Sengupta, D Sentenac, V Sequino, A Sergeev, Y Setyawati, D A Shaddock, T Shaffer, M S Shahriar, M Shaltev, B Shapiro, P Shawhan, A Sheperd, D H Shoemaker, D M Shoemaker, K Siellez, X Siemens, M Sieniawska, D Sigg, A D Silva, A Singer, L P Singer, A Singh, R Singh, A Singhal, A M Sintes, B J J Slagmolen, J R Smith, N D Smith, R J E Smith, E J Son, B Sorazu, F Sorrentino, T Souradeep, A K Srivastava, A Staley, M Steinke, J Steinlechner, S Steinlechner, D Steinmeyer, B C Stephens, S P Stevenson, R Stone, K A Strain, N Straniero, G Stratta, N A Strauss, S Strigin, R Sturani, A L Stuver, T Z Summerscales, L Sun, S Sunil, P J Sutton, B L Swinkels, M J Szczepańczyk, M Tacca, D Talukder, D B Tanner, M Tápai, S P Tarabrin, A Taracchini, R Taylor, T Theeg, M P Thirugnanasambandam, E G Thomas, M Thomas, P Thomas, K A Thorne, E Thrane, S Tiwari, V Tiwari, K V Tokmakov, K Toland, C Tomlinson, M Tonelli, Z Tornasi, C V Torres, C I Torrie, D Töyrä, F Travasso, G Traylor, D Trifirò, M C Tringali, L Trozzo, M Tse, M Turconi, D Tuyenbayev, D Ugolini, C S Unnikrishnan, A L Urban, S A Usman, H Vahlbruch, G Vajente, G Valdes, M Vallisneri, N van Bakel, M van Beuzekom, J F J van den Brand, C Van Den Broeck, D C Vander-Hyde, L van der Schaaf, J V van Heijningen, A A van Veggel, M Vardaro, S Vass, M Vasúth, R Vaulin, A Vecchio, G Vedovato, J Veitch, P J Veitch, K Venkateswara, D Verkindt, F Vetrano, A Viceré, S Vinciguerra, D J Vine, J-Y Vinet, S Vitale, T Vo, H Vocca, C Vorvick, D V Voss, W D Vousden, S P Vyatchanin, A R Wade, L E Wade, M Wade, M Walker, L Wallace, S Walsh, G Wang, H Wang, M Wang, X Wang, Y Wang, R L Ward, J Warner, M Was, B Weaver, L-W Wei, M Weinert, A J Weinstein, R Weiss, L Wen, P Weßels, T Westphal, K Wette, J T Whelan, B F Whiting, R D Williams, A R Williamson, J L Willis, B Willke, M H Wimmer, W Winkler, C C Wipf, H Wittel, G Woan, J Woehler, J Worden, J L Wright, D S Wu, G Wu, J Yablon, W Yam, H Yamamoto, C C Yancey, H Yu, M Yvert, A Zadrożny, L Zangrando, M Zanolin, J-P Zendri, M Zevin, L Zhang, M Zhang, Y Zhang, C Zhao, M Zhou, Z Zhou, X J Zhu, M E Zucker, S E Zuraw, J Zweizig, M Boyle, D Hemberger, L E Kidder, G Lovelace, S Ossokine, M Scheel, B Szilagyi, S Teukolsky
We report the observation of a gravitational-wave signal produced by the coalescence of two stellar-mass black holes. The signal, GW151226, was observed by the twin detectors of the Laser Interferometer Gravitational-Wave Observatory (LIGO) on December 26, 2015 at 03:38:53 UTC. The signal was initially identified within 70 s by an online matched-filter search targeting binary coalescences. Subsequent off-line analyses recovered GW151226 with a network signal-to-noise ratio of 13 and a significance greater than 5σ...
June 17, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27367378/properties-of-the-binary-black-hole-merger-gw150914
#15
B P Abbott, R Abbott, T D Abbott, M R Abernathy, F Acernese, K Ackley, C Adams, T Adams, P Addesso, R X Adhikari, V B Adya, C Affeldt, M Agathos, K Agatsuma, N Aggarwal, O D Aguiar, L Aiello, A Ain, P Ajith, B Allen, A Allocca, P A Altin, S B Anderson, W G Anderson, K Arai, M C Araya, C C Arceneaux, J S Areeda, N Arnaud, K G Arun, S Ascenzi, G Ashton, M Ast, S M Aston, P Astone, P Aufmuth, C Aulbert, S Babak, P Bacon, M K M Bader, P T Baker, F Baldaccini, G Ballardin, S W Ballmer, J C Barayoga, S E Barclay, B C Barish, D Barker, F Barone, B Barr, L Barsotti, M Barsuglia, D Barta, J Bartlett, I Bartos, R Bassiri, A Basti, J C Batch, C Baune, V Bavigadda, M Bazzan, B Behnke, M Bejger, A S Bell, C J Bell, B K Berger, J Bergman, G Bergmann, C P L Berry, D Bersanetti, A Bertolini, J Betzwieser, S Bhagwat, R Bhandare, I A Bilenko, G Billingsley, J Birch, R Birney, O Birnholtz, S Biscans, A Bisht, M Bitossi, C Biwer, M A Bizouard, J K Blackburn, C D Blair, D G Blair, R M Blair, S Bloemen, O Bock, T P Bodiya, M Boer, G Bogaert, C Bogan, A Bohe, P Bojtos, C Bond, F Bondu, R Bonnand, B A Boom, R Bork, V Boschi, S Bose, Y Bouffanais, A Bozzi, C Bradaschia, P R Brady, V B Braginsky, M Branchesi, J E Brau, T Briant, A Brillet, M Brinkmann, V Brisson, P Brockill, A F Brooks, D A Brown, D D Brown, N M Brown, C C Buchanan, A Buikema, T Bulik, H J Bulten, A Buonanno, D Buskulic, C Buy, R L Byer, L Cadonati, G Cagnoli, C Cahillane, J Calderón Bustillo, T Callister, E Calloni, J B Camp, K C Cannon, J Cao, C D Capano, E Capocasa, F Carbognani, S Caride, J Casanueva Diaz, C Casentini, S Caudill, M Cavaglià, F Cavalier, R Cavalieri, G Cella, C B Cepeda, L Cerboni Baiardi, G Cerretani, E Cesarini, R Chakraborty, T Chalermsongsak, S J Chamberlin, M Chan, S Chao, P Charlton, E Chassande-Mottin, H Y Chen, Y Chen, C Cheng, A Chincarini, A Chiummo, H S Cho, M Cho, J H Chow, N Christensen, Q Chu, S Chua, S Chung, G Ciani, F Clara, J A Clark, F Cleva, E Coccia, P-F Cohadon, A Colla, C G Collette, L Cominsky, M Constancio, A Conte, L Conti, D Cook, T R Corbitt, N Cornish, A Corsi, S Cortese, C A Costa, M W Coughlin, S B Coughlin, J-P Coulon, S T Countryman, P Couvares, E E Cowan, D M Coward, M J Cowart, D C Coyne, R Coyne, K Craig, J D E Creighton, J Cripe, S G Crowder, A Cumming, L Cunningham, E Cuoco, T Dal Canton, S L Danilishin, S D'Antonio, K Danzmann, N S Darman, V Dattilo, I Dave, H P Daveloza, M Davier, G S Davies, E J Daw, R Day, D DeBra, G Debreczeni, J Degallaix, M De Laurentis, S Deléglise, W Del Pozzo, T Denker, T Dent, H Dereli, V Dergachev, R De Rosa, R T DeRosa, R DeSalvo, C Devine, S Dhurandhar, M C Díaz, L Di Fiore, M Di Giovanni, A Di Lieto, S Di Pace, I Di Palma, A Di Virgilio, G Dojcinoski, V Dolique, F Donovan, K L Dooley, S Doravari, R Douglas, T P Downes, M Drago, R W P Drever, J C Driggers, Z Du, M Ducrot, S E Dwyer, T B Edo, M C Edwards, A Effler, H-B Eggenstein, P Ehrens, J Eichholz, S S Eikenberry, W Engels, R C Essick, Z Etienne, T Etzel, M Evans, T M Evans, R Everett, M Factourovich, V Fafone, H Fair, S Fairhurst, X Fan, Q Fang, S Farinon, B Farr, W M Farr, E Fauchon-Jones, M Favata, M Fays, H Fehrmann, M M Fejer, I Ferrante, E C Ferreira, F Ferrini, F Fidecaro, I Fiori, D Fiorucci, R P Fisher, R Flaminio, M Fletcher, J-D Fournier, S Franco, S Frasca, F Frasconi, Z Frei, A Freise, R Frey, V Frey, T T Fricke, P Fritschel, V V Frolov, P Fulda, M Fyffe, H A G Gabbard, S M Gaebel, J R Gair, L Gammaitoni, S G Gaonkar, F Garufi, A Gatto, G Gaur, N Gehrels, G Gemme, B Gendre, E Genin, A Gennai, J George, L Gergely, V Germain, Archisman Ghosh, S Ghosh, J A Giaime, K D Giardina, A Giazotto, K Gill, A Glaefke, E Goetz, R Goetz, L Gondan, G González, J M Gonzalez Castro, A Gopakumar, N A Gordon, M L Gorodetsky, S E Gossan, M Gosselin, R Gouaty, C Graef, P B Graff, M Granata, A Grant, S Gras, C Gray, G Greco, A C Green, P Groot, H Grote, S Grunewald, G M Guidi, X Guo, A Gupta, M K Gupta, K E Gushwa, E K Gustafson, R Gustafson, J J Hacker, B R Hall, E D Hall, G Hammond, M Haney, M M Hanke, J Hanks, C Hanna, M D Hannam, J Hanson, T Hardwick, J Harms, G M Harry, I W Harry, M J Hart, M T Hartman, C-J Haster, K Haughian, J Healy, A Heidmann, M C Heintze, H Heitmann, P Hello, G Hemming, M Hendry, I S Heng, J Hennig, A W Heptonstall, M Heurs, S Hild, D Hoak, K A Hodge, D Hofman, S E Hollitt, K Holt, D E Holz, P Hopkins, D J Hosken, J Hough, E A Houston, E J Howell, Y M Hu, S Huang, E A Huerta, D Huet, B Hughey, S Husa, S H Huttner, T Huynh-Dinh, A Idrisy, N Indik, D R Ingram, R Inta, H N Isa, J-M Isac, M Isi, G Islas, T Isogai, B R Iyer, K Izumi, T Jacqmin, H Jang, K Jani, P Jaranowski, S Jawahar, F Jiménez-Forteza, W W Johnson, N K Johnson-McDaniel, D I Jones, R Jones, R J G Jonker, L Ju, Haris K, C V Kalaghatgi, V Kalogera, S Kandhasamy, G Kang, J B Kanner, S Karki, M Kasprzack, E Katsavounidis, W Katzman, S Kaufer, T Kaur, K Kawabe, F Kawazoe, F Kéfélian, M S Kehl, D Keitel, D B Kelley, W Kells, R Kennedy, J S Key, A Khalaidovski, F Y Khalili, I Khan, S Khan, Z Khan, E A Khazanov, N Kijbunchoo, C Kim, J Kim, K Kim, Nam-Gyu Kim, Namjun Kim, Y-M Kim, E J King, P J King, D L Kinzel, J S Kissel, L Kleybolte, S Klimenko, S M Koehlenbeck, K Kokeyama, S Koley, V Kondrashov, A Kontos, M Korobko, W Z Korth, I Kowalska, D B Kozak, V Kringel, B Krishnan, A Królak, C Krueger, G Kuehn, P Kumar, L Kuo, A Kutynia, B D Lackey, M Landry, J Lange, B Lantz, P D Lasky, A Lazzarini, C Lazzaro, P Leaci, S Leavey, E O Lebigot, C H Lee, H K Lee, H M Lee, K Lee, A Lenon, M Leonardi, J R Leong, N Leroy, N Letendre, Y Levin, B M Levine, T G F Li, A Libson, T B Littenberg, N A Lockerbie, J Logue, A L Lombardi, L T London, J E Lord, M Lorenzini, V Loriette, M Lormand, G Losurdo, J D Lough, C O Lousto, G Lovelace, H Lück, A P Lundgren, J Luo, R Lynch, Y Ma, T MacDonald, B Machenschalk, M MacInnis, D M Macleod, F Magaña-Sandoval, R M Magee, M Mageswaran, E Majorana, I Maksimovic, V Malvezzi, N Man, I Mandel, V Mandic, V Mangano, G L Mansell, M Manske, M Mantovani, F Marchesoni, F Marion, S Márka, Z Márka, A S Markosyan, E Maros, F Martelli, L Martellini, I W Martin, R M Martin, D V Martynov, J N Marx, K Mason, A Masserot, T J Massinger, M Masso-Reid, F Matichard, L Matone, N Mavalvala, N Mazumder, G Mazzolo, R McCarthy, D E McClelland, S McCormick, S C McGuire, G McIntyre, J McIver, D J McManus, S T McWilliams, D Meacher, G D Meadors, J Meidam, A Melatos, G Mendell, D Mendoza-Gandara, R A Mercer, E Merilh, M Merzougui, S Meshkov, C Messenger, C Messick, P M Meyers, F Mezzani, H Miao, C Michel, H Middleton, E E Mikhailov, L Milano, J Miller, M Millhouse, Y Minenkov, J Ming, S Mirshekari, C Mishra, S Mitra, V P Mitrofanov, G Mitselmakher, R Mittleman, A Moggi, M Mohan, S R P Mohapatra, M Montani, B C Moore, C J Moore, D Moraru, G Moreno, S R Morriss, K Mossavi, B Mours, C M Mow-Lowry, C L Mueller, G Mueller, A W Muir, Arunava Mukherjee, D Mukherjee, S Mukherjee, N Mukund, A Mullavey, J Munch, D J Murphy, P G Murray, A Mytidis, I Nardecchia, L Naticchioni, R K Nayak, V Necula, K Nedkova, G Nelemans, M Neri, A Neunzert, G Newton, T T Nguyen, A B Nielsen, S Nissanke, A Nitz, F Nocera, D Nolting, M E Normandin, L K Nuttall, J Oberling, E Ochsner, J O'Dell, E Oelker, G H Ogin, J J Oh, S H Oh, F Ohme, M Oliver, P Oppermann, Richard J Oram, B O'Reilly, R O'Shaughnessy, D J Ottaway, R S Ottens, H Overmier, B J Owen, A Pai, S A Pai, J R Palamos, O Palashov, C Palomba, A Pal-Singh, H Pan, Y Pan, C Pankow, F Pannarale, B C Pant, F Paoletti, A Paoli, M A Papa, H R Paris, W Parker, D Pascucci, A Pasqualetti, R Passaquieti, D Passuello, B Patricelli, Z Patrick, B L Pearlstone, M Pedraza, R Pedurand, L Pekowsky, A Pele, S Penn, A Perreca, H P Pfeiffer, M Phelps, O Piccinni, M Pichot, F Piergiovanni, V Pierro, G Pillant, L Pinard, I M Pinto, M Pitkin, R Poggiani, P Popolizio, A Post, J Powell, J Prasad, V Predoi, S S Premachandra, T Prestegard, L R Price, M Prijatelj, M Principe, S Privitera, G A Prodi, L Prokhorov, O Puncken, M Punturo, P Puppo, M Pürrer, H Qi, J Qin, V Quetschke, E A Quintero, R Quitzow-James, F J Raab, D S Rabeling, H Radkins, P Raffai, S Raja, M Rakhmanov, P Rapagnani, V Raymond, M Razzano, V Re, J Read, C M Reed, T Regimbau, L Rei, S Reid, D H Reitze, H Rew, S D Reyes, F Ricci, K Riles, N A Robertson, R Robie, F Robinet, A Rocchi, L Rolland, J G Rollins, V J Roma, R Romano, G Romanov, J H Romie, D Rosińska, C Röver, S Rowan, A Rüdiger, P Ruggi, K Ryan, S Sachdev, T Sadecki, L Sadeghian, L Salconi, M Saleem, F Salemi, A Samajdar, L Sammut, E J Sanchez, V Sandberg, B Sandeen, J R Sanders, B Sassolas, B S Sathyaprakash, P R Saulson, O Sauter, R L Savage, A Sawadsky, P Schale, R Schilling, J Schmidt, P Schmidt, R Schnabel, R M S Schofield, A Schönbeck, E Schreiber, D Schuette, B F Schutz, J Scott, S M Scott, D Sellers, A S Sengupta, D Sentenac, V Sequino, A Sergeev, G Serna, Y Setyawati, A Sevigny, D A Shaddock, S Shah, M S Shahriar, M Shaltev, Z Shao, B Shapiro, P Shawhan, A Sheperd, D H Shoemaker, D M Shoemaker, K Siellez, X Siemens, D Sigg, A D Silva, D Simakov, A Singer, L P Singer, A Singh, R Singh, A Singhal, A M Sintes, B J J Slagmolen, J R Smith, N D Smith, R J E Smith, E J Son, B Sorazu, F Sorrentino, T Souradeep, A K Srivastava, A Staley, M Steinke, J Steinlechner, S Steinlechner, D Steinmeyer, B C Stephens, S P Stevenson, R Stone, K A Strain, N Straniero, G Stratta, N A Strauss, S Strigin, R Sturani, A L Stuver, T Z Summerscales, L Sun, P J Sutton, B L Swinkels, M J Szczepańczyk, M Tacca, D Talukder, D B Tanner, M Tápai, S P Tarabrin, A Taracchini, R Taylor, T Theeg, M P Thirugnanasambandam, E G Thomas, M Thomas, P Thomas, K A Thorne, K S Thorne, E Thrane, S Tiwari, V Tiwari, K V Tokmakov, C Tomlinson, M Tonelli, C V Torres, C I Torrie, D Töyrä, F Travasso, G Traylor, D Trifirò, M C Tringali, L Trozzo, M Tse, M Turconi, D Tuyenbayev, D Ugolini, C S Unnikrishnan, A L Urban, S A Usman, H Vahlbruch, G Vajente, G Valdes, N van Bakel, M van Beuzekom, J F J van den Brand, C Van Den Broeck, D C Vander-Hyde, L van der Schaaf, M V van der Sluys, J V van Heijningen, A Vañó-Viñuales, A A van Veggel, M Vardaro, S Vass, M Vasúth, R Vaulin, A Vecchio, G Vedovato, J Veitch, P J Veitch, K Venkateswara, D Verkindt, F Vetrano, A Viceré, S Vinciguerra, D J Vine, J-Y Vinet, S Vitale, T Vo, H Vocca, C Vorvick, D Voss, W D Vousden, S P Vyatchanin, A R Wade, L E Wade, M Wade, M Walker, L Wallace, S Walsh, G Wang, H Wang, M Wang, X Wang, Y Wang, R L Ward, J Warner, M Was, B Weaver, L-W Wei, M Weinert, A J Weinstein, R Weiss, T Welborn, L Wen, P Weßels, T Westphal, K Wette, J T Whelan, D J White, B F Whiting, R D Williams, A R Williamson, J L Willis, B Willke, M H Wimmer, W Winkler, C C Wipf, H Wittel, G Woan, J Worden, J L Wright, G Wu, J Yablon, W Yam, H Yamamoto, C C Yancey, M J Yap, H Yu, M Yvert, A Zadrożny, L Zangrando, M Zanolin, J-P Zendri, M Zevin, F Zhang, L Zhang, M Zhang, Y Zhang, C Zhao, M Zhou, Z Zhou, X J Zhu, M E Zucker, S E Zuraw, J Zweizig, M Boyle, B Brügmann, M Campanelli, M Clark, D Hamberger, L E Kidder, M Kinsey, P Laguna, S Ossokine, M A Scheel, B Szilagyi, S Teukolsky, Y Zlochower
On September 14, 2015, the Laser Interferometer Gravitational-Wave Observatory (LIGO) detected a gravitational-wave transient (GW150914); we characterize the properties of the source and its parameters. The data around the time of the event were analyzed coherently across the LIGO network using a suite of accurate waveform models that describe gravitational waves from a compact binary system in general relativity. GW150914 was produced by a nearly equal mass binary black hole of masses 36_{-4}^{+5}M_{⊙} and 29_{-4}^{+4}M_{⊙}; for each parameter we report the median value and the range of the 90% credible interval...
June 17, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27330452/2014-epilepsy-benchmarks-area-iii-improve-treatment-options-for-controlling-seizures-and-epilepsy-related-conditions-without-side-effects
#16
Dennis Dlugos, Greg Worrell, Kathryn Davis, William Stacey, Jerzy Szaflarski, Andres Kanner, Sridhar Sunderam, Mike Rogawski, Patrice Jackson-Ayotunde, Tobias Loddenkemper, Beate Diehl, Brandy Fureman, Ray Dingledine
No abstract text is available yet for this article.
May 2016: Epilepsy Currents
https://www.readbyqxmd.com/read/27322691/psychosis-of-epilepsy-a-multifaceted-neuropsychiatric-disorder
#17
REVIEW
Andres M Kanner, Ana Maria Rivas-Grajales
Psychosis of epilepsy (POE) is a term applied to a group of psychotic disorders with a distinct phenomenology in which potential etiopathogenic mechanisms are believed to be closely related to a seizure disorder. POE can present as interictal psychotic episodes, which may often differ semiologically from primary schizophrenic disorder. They may present as ictal or postictal psychotic episodes and may be the expression of an iatrogenic process to pharmacologic and/or surgical interventions.Epilepsy and POE have a complex and bidirectional relation, as not only are patients with epilepsy at greater risk of developing a psychotic disorder, but patients with a primary psychotic disorder are also at greater risk of developing epilepsy...
June 2016: CNS Spectrums
https://www.readbyqxmd.com/read/27314708/tests-of-general-relativity-with-gw150914
#18
B P Abbott, R Abbott, T D Abbott, M R Abernathy, F Acernese, K Ackley, C Adams, T Adams, P Addesso, R X Adhikari, V B Adya, C Affeldt, M Agathos, K Agatsuma, N Aggarwal, O D Aguiar, L Aiello, A Ain, P Ajith, B Allen, A Allocca, P A Altin, S B Anderson, W G Anderson, K Arai, M C Araya, C C Arceneaux, J S Areeda, N Arnaud, K G Arun, S Ascenzi, G Ashton, M Ast, S M Aston, P Astone, P Aufmuth, C Aulbert, S Babak, P Bacon, M K M Bader, P T Baker, F Baldaccini, G Ballardin, S W Ballmer, J C Barayoga, S E Barclay, B C Barish, D Barker, F Barone, B Barr, L Barsotti, M Barsuglia, D Barta, J Bartlett, I Bartos, R Bassiri, A Basti, J C Batch, C Baune, V Bavigadda, M Bazzan, B Behnke, M Bejger, A S Bell, C J Bell, B K Berger, J Bergman, G Bergmann, C P L Berry, D Bersanetti, A Bertolini, J Betzwieser, S Bhagwat, R Bhandare, I A Bilenko, G Billingsley, J Birch, R Birney, O Birnholtz, S Biscans, A Bisht, M Bitossi, C Biwer, M A Bizouard, J K Blackburn, C D Blair, D G Blair, R M Blair, S Bloemen, O Bock, T P Bodiya, M Boer, G Bogaert, C Bogan, A Bohe, P Bojtos, C Bond, F Bondu, R Bonnand, B A Boom, R Bork, V Boschi, S Bose, Y Bouffanais, A Bozzi, C Bradaschia, P R Brady, V B Braginsky, M Branchesi, J E Brau, T Briant, A Brillet, M Brinkmann, V Brisson, P Brockill, A F Brooks, D A Brown, D D Brown, N M Brown, C C Buchanan, A Buikema, T Bulik, H J Bulten, A Buonanno, D Buskulic, C Buy, R L Byer, L Cadonati, G Cagnoli, C Cahillane, J Calderón Bustillo, T Callister, E Calloni, J B Camp, K C Cannon, J Cao, C D Capano, E Capocasa, F Carbognani, S Caride, J Casanueva Diaz, C Casentini, S Caudill, M Cavaglià, F Cavalier, R Cavalieri, G Cella, C B Cepeda, L Cerboni Baiardi, G Cerretani, E Cesarini, R Chakraborty, T Chalermsongsak, S J Chamberlin, M Chan, S Chao, P Charlton, E Chassande-Mottin, H Y Chen, Y Chen, C Cheng, A Chincarini, A Chiummo, H S Cho, M Cho, J H Chow, N Christensen, Q Chu, S Chua, S Chung, G Ciani, F Clara, J A Clark, F Cleva, E Coccia, P-F Cohadon, A Colla, C G Collette, L Cominsky, M Constancio, A Conte, L Conti, D Cook, T R Corbitt, N Cornish, A Corsi, S Cortese, C A Costa, M W Coughlin, S B Coughlin, J-P Coulon, S T Countryman, P Couvares, E E Cowan, D M Coward, M J Cowart, D C Coyne, R Coyne, K Craig, J D E Creighton, J Cripe, S G Crowder, A Cumming, L Cunningham, E Cuoco, T Dal Canton, S L Danilishin, S D'Antonio, K Danzmann, N S Darman, V Dattilo, I Dave, H P Daveloza, M Davier, G S Davies, E J Daw, R Day, D DeBra, G Debreczeni, J Degallaix, M De Laurentis, S Deléglise, W Del Pozzo, T Denker, T Dent, H Dereli, V Dergachev, R De Rosa, R T DeRosa, R DeSalvo, S Dhurandhar, M C Díaz, L Di Fiore, M Di Giovanni, A Di Lieto, S Di Pace, I Di Palma, A Di Virgilio, G Dojcinoski, V Dolique, F Donovan, K L Dooley, S Doravari, R Douglas, T P Downes, M Drago, R W P Drever, J C Driggers, Z Du, M Ducrot, S E Dwyer, T B Edo, M C Edwards, A Effler, H-B Eggenstein, P Ehrens, J Eichholz, S S Eikenberry, W Engels, R C Essick, T Etzel, M Evans, T M Evans, R Everett, M Factourovich, V Fafone, H Fair, S Fairhurst, X Fan, Q Fang, S Farinon, B Farr, W M Farr, M Favata, M Fays, H Fehrmann, M M Fejer, I Ferrante, E C Ferreira, F Ferrini, F Fidecaro, I Fiori, D Fiorucci, R P Fisher, R Flaminio, M Fletcher, J-D Fournier, S Franco, S Frasca, F Frasconi, Z Frei, A Freise, R Frey, V Frey, T T Fricke, P Fritschel, V V Frolov, P Fulda, M Fyffe, H A G Gabbard, J R Gair, L Gammaitoni, S G Gaonkar, F Garufi, A Gatto, G Gaur, N Gehrels, G Gemme, B Gendre, E Genin, A Gennai, J George, L Gergely, V Germain, Abhirup Ghosh, Archisman Ghosh, S Ghosh, J A Giaime, K D Giardina, A Giazotto, K Gill, A Glaefke, E Goetz, R Goetz, L Gondan, G González, J M Gonzalez Castro, A Gopakumar, N A Gordon, M L Gorodetsky, S E Gossan, M Gosselin, R Gouaty, C Graef, P B Graff, M Granata, A Grant, S Gras, C Gray, G Greco, A C Green, P Groot, H Grote, S Grunewald, G M Guidi, X Guo, A Gupta, M K Gupta, K E Gushwa, E K Gustafson, R Gustafson, J J Hacker, B R Hall, E D Hall, G Hammond, M Haney, M M Hanke, J Hanks, C Hanna, M D Hannam, J Hanson, T Hardwick, J Harms, G M Harry, I W Harry, M J Hart, M T Hartman, C-J Haster, K Haughian, J Healy, A Heidmann, M C Heintze, H Heitmann, P Hello, G Hemming, M Hendry, I S Heng, J Hennig, A W Heptonstall, M Heurs, S Hild, D Hoak, K A Hodge, D Hofman, S E Hollitt, K Holt, D E Holz, P Hopkins, D J Hosken, J Hough, E A Houston, E J Howell, Y M Hu, S Huang, E A Huerta, D Huet, B Hughey, S Husa, S H Huttner, T Huynh-Dinh, A Idrisy, N Indik, D R Ingram, R Inta, H N Isa, J-M Isac, M Isi, G Islas, T Isogai, B R Iyer, K Izumi, T Jacqmin, H Jang, K Jani, P Jaranowski, S Jawahar, F Jiménez-Forteza, W W Johnson, N K Johnson-McDaniel, D I Jones, R Jones, R J G Jonker, L Ju, M K Haris, C V Kalaghatgi, V Kalogera, S Kandhasamy, G Kang, J B Kanner, S Karki, M Kasprzack, E Katsavounidis, W Katzman, S Kaufer, T Kaur, K Kawabe, F Kawazoe, F Kéfélian, M S Kehl, D Keitel, D B Kelley, W Kells, R Kennedy, J S Key, A Khalaidovski, F Y Khalili, I Khan, S Khan, Z Khan, E A Khazanov, N Kijbunchoo, C Kim, J Kim, K Kim, Nam-Gyu Kim, Namjun Kim, Y-M Kim, E J King, P J King, D L Kinzel, J S Kissel, L Kleybolte, S Klimenko, S M Koehlenbeck, K Kokeyama, S Koley, V Kondrashov, A Kontos, M Korobko, W Z Korth, I Kowalska, D B Kozak, V Kringel, B Krishnan, A Królak, C Krueger, G Kuehn, P Kumar, L Kuo, A Kutynia, B D Lackey, M Landry, J Lange, B Lantz, P D Lasky, A Lazzarini, C Lazzaro, P Leaci, S Leavey, E O Lebigot, C H Lee, H K Lee, H M Lee, K Lee, A Lenon, M Leonardi, J R Leong, N Leroy, N Letendre, Y Levin, B M Levine, T G F Li, A Libson, T B Littenberg, N A Lockerbie, J Logue, A L Lombardi, L T London, J E Lord, M Lorenzini, V Loriette, M Lormand, G Losurdo, J D Lough, C O Lousto, G Lovelace, H Lück, A P Lundgren, J Luo, R Lynch, Y Ma, T MacDonald, B Machenschalk, M MacInnis, D M Macleod, F Magaña-Sandoval, R M Magee, M Mageswaran, E Majorana, I Maksimovic, V Malvezzi, N Man, I Mandel, V Mandic, V Mangano, G L Mansell, M Manske, M 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Nardecchia, L Naticchioni, R K Nayak, V Necula, K Nedkova, G Nelemans, M Neri, A Neunzert, G Newton, T T Nguyen, A B Nielsen, S Nissanke, A Nitz, F Nocera, D Nolting, M E Normandin, L K Nuttall, J Oberling, E Ochsner, J O'Dell, E Oelker, G H Ogin, J J Oh, S H Oh, F Ohme, M Oliver, P Oppermann, Richard J Oram, B O'Reilly, R O'Shaughnessy, D J Ottaway, R S Ottens, H Overmier, B J Owen, A Pai, S A Pai, J R Palamos, O Palashov, C Palomba, A Pal-Singh, H Pan, Y Pan, C Pankow, F Pannarale, B C Pant, F Paoletti, A Paoli, M A Papa, H R Paris, W Parker, D Pascucci, A Pasqualetti, R Passaquieti, D Passuello, B Patricelli, Z Patrick, B L Pearlstone, M Pedraza, R Pedurand, L Pekowsky, A Pele, S Penn, A Perreca, H P Pfeiffer, M Phelps, O Piccinni, M Pichot, F Piergiovanni, V Pierro, G Pillant, L Pinard, I M Pinto, M Pitkin, R Poggiani, P Popolizio, A Post, J Powell, J Prasad, V Predoi, S S Premachandra, T Prestegard, L R Price, M Prijatelj, M Principe, S Privitera, R Prix, G A Prodi, L Prokhorov, O Puncken, M Punturo, P Puppo, M Pürrer, H Qi, J Qin, V Quetschke, E A Quintero, R Quitzow-James, F J Raab, D S Rabeling, H Radkins, P Raffai, S Raja, M Rakhmanov, P Rapagnani, V Raymond, M Razzano, V Re, J Read, C M Reed, T Regimbau, L Rei, S Reid, D H Reitze, H Rew, S D Reyes, F Ricci, K Riles, N A Robertson, R Robie, F Robinet, A Rocchi, L Rolland, J G Rollins, V J Roma, R Romano, G Romanov, J H Romie, D Rosińska, S Rowan, A Rüdiger, P Ruggi, K Ryan, S Sachdev, T Sadecki, L Sadeghian, L Salconi, M Saleem, F Salemi, A Samajdar, L Sammut, E J Sanchez, V Sandberg, B Sandeen, J R Sanders, B Sassolas, B S Sathyaprakash, P R Saulson, O Sauter, R L Savage, A Sawadsky, P Schale, R Schilling, J Schmidt, P Schmidt, R Schnabel, R M S Schofield, A Schönbeck, E Schreiber, D Schuette, B F Schutz, J Scott, S M Scott, D Sellers, A S Sengupta, D Sentenac, V Sequino, A Sergeev, G Serna, Y Setyawati, A Sevigny, D A Shaddock, S Shah, M S Shahriar, M Shaltev, Z Shao, B Shapiro, P Shawhan, A Sheperd, D H Shoemaker, D M Shoemaker, K Siellez, X Siemens, D Sigg, A D Silva, D Simakov, A Singer, L P Singer, A Singh, R Singh, A Singhal, A M Sintes, B J J Slagmolen, J R Smith, N D Smith, R J E Smith, E J Son, B Sorazu, F Sorrentino, T Souradeep, A K Srivastava, A Staley, M Steinke, J Steinlechner, S Steinlechner, D Steinmeyer, B C Stephens, R Stone, K A Strain, N Straniero, G Stratta, N A Strauss, S Strigin, R Sturani, A L Stuver, T Z Summerscales, L Sun, P J Sutton, B L Swinkels, M J Szczepańczyk, M Tacca, D Talukder, D B Tanner, M Tápai, S P Tarabrin, A Taracchini, R Taylor, T Theeg, M P Thirugnanasambandam, E G Thomas, M Thomas, P Thomas, K A Thorne, K S Thorne, E Thrane, S Tiwari, V Tiwari, K V Tokmakov, C Tomlinson, M Tonelli, C V Torres, C I Torrie, D Töyrä, F Travasso, G Traylor, D Trifirò, M C Tringali, L Trozzo, M Tse, M Turconi, D Tuyenbayev, D Ugolini, C S Unnikrishnan, A L Urban, S A Usman, H Vahlbruch, G Vajente, G Valdes, M Vallisneri, N van Bakel, M van Beuzekom, J F J van den 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Hemberger, L E Kidder, S Ossokine, M A Scheel, B Szilagyi, S Teukolsky, Y Zlochower
The LIGO detection of GW150914 provides an unprecedented opportunity to study the two-body motion of a compact-object binary in the large-velocity, highly nonlinear regime, and to witness the final merger of the binary and the excitation of uniquely relativistic modes of the gravitational field. We carry out several investigations to determine whether GW150914 is consistent with a binary black-hole merger in general relativity. We find that the final remnant's mass and spin, as determined from the low-frequency (inspiral) and high-frequency (postinspiral) phases of the signal, are mutually consistent with the binary black-hole solution in general relativity...
June 3, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27251756/a-non-aggressive-highly-efficient-enzymatic-method-for-dissociation-of-human-brain-tumors-and-brain-tissues-to-viable-single-cells
#19
Ilan Volovitz, Netanel Shapira, Haim Ezer, Aviv Gafni, Merav Lustgarten, Tal Alter, Idan Ben-Horin, Ori Barzilai, Tal Shahar, Andrew Kanner, Itzhak Fried, Igor Veshchev, Rachel Grossman, Zvi Ram
BACKGROUND: Conducting research on the molecular biology, immunology, and physiology of brain tumors (BTs) and primary brain tissues requires the use of viably dissociated single cells. Inadequate methods for tissue dissociation generate considerable loss in the quantity of single cells produced and in the produced cells' viability. Improper dissociation may also demote the quality of data attained in functional and molecular assays due to the presence of large quantities cellular debris containing immune-activatory danger associated molecular patterns, and due to the increased quantities of degraded proteins and RNA...
2016: BMC Neuroscience
https://www.readbyqxmd.com/read/27245308/connecting-malfunctioning-glial-cells-and-brain-degenerative-disorders
#20
REVIEW
Natalie Kaminsky, Ofer Bihari, Sivan Kanner, Ari Barzilai
The DNA damage response (DDR) is a complex biological system activated by different types of DNA damage. Mutations in certain components of the DDR machinery can lead to genomic instability disorders that culminate in tissue degeneration, premature aging, and various types of cancers. Intriguingly, malfunctioning DDR plays a role in the etiology of late onset brain degenerative disorders such as Parkinson's, Alzheimer's, and Huntington's diseases. For many years, brain degenerative disorders were thought to result from aberrant neural death...
June 2016: Genomics, Proteomics & Bioinformatics
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