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https://www.readbyqxmd.com/read/29771770/biliary-stenosis-and-gastric-outlet-obstruction-late-complications-after-acute-pancreatitis-with-pancreatic-duct-disruption
#1
Motokazu Sugimoto, David P Sonntag, Greggory S Flint, Cody J Boyce, John C Kirkham, Tyler J Harris, Sean M Carr, Brent D Nelson, Don A Bell, Joshua G Barton, L William Traverso
OBJECTIVES: Pancreatic duct disruption (PDD) after acute pancreatitis can cause pancreatic collections in the early phase and biliary stenosis (BS) or gastric outlet obstruction (GOO) in the late phase. We aimed to document those late complications after moderate or severe acute pancreatitis. METHODS: Between September 2010 and August 2014, 141 patients showed pancreatic collections on computed tomography. Percutaneous drainage was primarily performed for patients with signs or symptoms of uncontrolled pancreatic juice leakage...
May 15, 2018: Pancreas
https://www.readbyqxmd.com/read/29766227/noncontrast-computed-tomography-factors-predictive-of-extracorporeal-shock-wave-lithotripsy-outcomes-in-patients-with-pancreatic-duct-stones
#2
Ri Liu, Weiwei Su, Jing Gong, Yu Zhang, Jianping Lu
PURPOSE: To assess the usefulness of factors unique to NCCT for the prediction of ESWL outcomes in patients with pancreatic duct stones. MATERIALS AND METHODS: We retrospectively evaluated 148 patients with multiple PDS who had undergone ESWL therapy. All patients received an examination for NCCT both before and after ESWL. The following parameters were measured and recorded: patient characteristics including sex and age; NCCT parameters including mean stone length, mean stone volumes before and after ESWL, mean value of CT attenuation, standard deviation of CT attenuation, variation coefficient of CT attenuation, skin-to-stone distance, and pancreatic duct diameter; ESWL outcome indexes including stone clearance rate calculated using the formula [Formula: see text], and the number of ESWL sessions...
May 15, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29764449/primo-software-as-a-tool-for-monte-carlo-simulations-of-intensity-modulated-radiotherapy-a-feasibility-study
#3
Alessandro Esposito, Sofia Silva, Jorge Oliveira, Joana Lencart, João Santos
BACKGROUND: IMRT provides higher dose conformation to the target and dose sparing to surrounding tissues than 3DCRT. Monte Carlo method in Medical Physics is not a novelty to approach dosimetric problems. A new PENELOPE based code named PRIMO recently was published. The most intriguing features of PRIMO are the user-friendly approach, the stand-alone property and the built-in definition of different linear accelerators models. Nevertheless, IMRT simulations are not yet implemented. METHODS: A Varian Trilogy with a Millennium120 MLC and a Varian Novalis with 120HD MLC were studied...
May 15, 2018: Radiation Oncology
https://www.readbyqxmd.com/read/29763648/autism-spectrum-disorder-classification-diagnosis-and-therapy
#4
REVIEW
Samata R Sharma, Xenia Gonda, Frank I Tarazi
Autism Spectrum Disorder (ASD) refers to a group of neurodevelopmental disorders including autism, Asperger's syndrome (AS) and pervasive developmental disorder-not otherwise specified (PDD-NOS). The new diagnostic criteria of ASD focuses on two core domains: social communication impairment and restricted interests/repetitive behaviors. The prevalence of ASD has been steadily increasing over the past two decades, with current estimates reaching up to 1 in 36 children. Hereditary factors, parental history of psychiatric disorders, pre-term births, and fetal exposure to psychotropic drugs or insecticides have all been linked to higher risk of ASD...
May 12, 2018: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29763511/a-review-of-non-invasive-imaging-in-extramammary-paget-s-disease
#5
REVIEW
Claire-Audrey Y Bayan, Trisha Khanna, Veronica Rotemberg, Faramarz H Samie, Nathalie C Zeitouni
Extramammary Paget's Disease (EMPD) is a rare intraepithelial adenocarcinoma that classically manifests with pruritic, erythematous, scaling plaques. The clinical picture frequently mimics inflammatory or infectious conditions, and is thus commonly misdiagnosed. The assessment of tumor margins is equally challenging as tumors have a propensity to spread beyond clinically visible boundaries. Appropriate non-invasive diagnostic tools can assist in the early detection, diagnosis, and management of EMPD. This paper will review the literature on non-invasive imaging modalities used in EMPD...
May 15, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29762379/demographic-and-clinical-correlates-of-mucosal-disaccharidase-deficiencies-in-children-with-functional-dyspepsia
#6
Bruno P Chumpitazi, Claudia C Robayo-Torres, Cynthia M Tsai, Antone R Opekun, Susan S Baker, Buford L Nichols, Mark A Gilger
BACKGROUND: A subset of children with functional gastrointestinal disorders (FGIDs), which includes functional dyspepsia, may have duodenal disaccharidase deficiencies. OBJECTIVES: To determine the frequency, demographics, and clinical characteristics associated with duodenal disaccharidase deficiencies in children with functional dyspepsia. METHODS: Children ages 4 to 18 years undergoing esophagogastroduodenoscopy (EGD) evaluation for dyspepsia were enrolled in either a retrospective (study 1) or prospective (study 2) evaluation...
June 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29757472/technical-note-predicting-dose-distribution-with-replacing-stopping-power-ratio-for-inter-fractional-motion-and-intra-fractional-motion-during-carbon-ion-radiotherapy-with-passive-irradiation-method-for-stage-i-lung-cancer
#7
Yoshiki Kubota, Makoto Sakai, Mutsumi Tashiro, Jun-Ichi Saitoh, Takanori Abe, Tatsuya Ohno, Takashi Nakano
PURPOSE: We designed and evaluated a simple method for predicting the effects of intra-fractional and/or inter-fractional motion on dose distribution during carbon ion radiotherapy (CIRT) for solitary-lesion stage I lung cancer. METHODS: The proposed method uses computed tomography (CT) images from treatment planning and intra-tumoral and/or inter-tumoral displacement. The predicted dose distribution (PDD) was calculated by replacing the current tumor region with the stopping power ratio (SPR) of the lung, and replacing the moved tumor region with the SPR of the tumor...
May 14, 2018: Medical Physics
https://www.readbyqxmd.com/read/29753322/clinical-outcomes-of-interactive-intensive-and-individual-3i-play-therapy-for-children-with-asd-a-two-year-follow-up-study
#8
Elodie Tilmont Pittala, Yann Saint-Georges-Chaumet, Claire Favrot, Antoine Tanet, David Cohen, Catherine Saint-Georges
BACKGROUND: The outcomes of psycho-educational interventions for Autism Spectrum Disorders (ASDs) comorbid with severe to moderate intellectual disability (ID) are insufficiently documented. In this prospective study, we examined a developmental individual, interactive and intensive approach, called the '3i method', which is based on play therapy. METHODS: Twenty DSM-IV-TR ASD subjects (mean chronological age 63.8 ± 37.8 months; mean developmental age 19.5 ± 6...
May 12, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29749088/ring-opening-polymerization-of-a-new-diester-cyclic-dimer-of-mandelic-and-glycolic-acid-an-efficient-synthesis-method-for-derivatives-of-amorphous-polyglycolide-with-high-t-g
#9
Hajime Nakajima, Katja Loos, Shinobu Ishizu, Yoshiharu Kimura
In this study, poly(mandelate-co-glycolate) (PMG), a modified polyglycolide (PGL), is prepared by ring-opening polymerization (ROP) of L-3-phenyl-1,4-dioxane-2,5-dione (PDD); the cyclic dimer of biobased mandelic acid and glycolic acid. The resulting polymer shows an increased glass transition temperature (Tg ) due to the incorporation of phenyl groups in the chain. High molecular weight PMG is obtained by bulk ROP at 150 °C, and it exhibits a glassy amorphous state with enhanced thermal properties such as a Tg being 35 °C higher than conventional PGL...
May 11, 2018: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/29746014/dosimetric-and-geometric-characteristics-of-a-small-animal-image-guided-irradiator-using-3d-dosimetry-optical-ct-scanner
#10
Yong Hum Na, Yi-Fang Wang, Paul J Black, Christian Velten, Xin Qian, Shih-Chi Lin, John Adamovics, Cheng-Shie Wuu
PURPOSE: The precise dosimetric and geometric characteristics of small animal irradiators are essential to achieving reproducible dose delivery, especially in cases where image-guidance is utilized. Currently, radiochromic film is the established measurement tool used to evaluate beam characteristics for these systems. However, only 2D information can be acquired with film. This study characterized both the dosimetric and geometric properties of the small animal research radiation platform (SARRP, Xstrahl) for commissioning purposes using a 3D radiochromic dosimetry system with a sub-millimeter resolution optical computed tomography (OCT) scanner...
May 10, 2018: Medical Physics
https://www.readbyqxmd.com/read/29744554/-current-and-established-diagnostic-modalities-for-bladder-cancer
#11
REVIEW
D Zaak, C Ohlmann, A Stenzl
INTRODUCTION: In this paper, current guidelines regarding diagnostic and staging modalities of urothelial cancer of the bladder are summarized and an overview of endoscopic, imaging, and molecular methods currently being tested are outlined. METHODS: Relevant passages from current guidelines and recent literature as well as to a certain extent our own research are examined. RESULTS: Over the last decade, imaging mainly in the form of photodynamic diagnosis (PDD) has undergone further development and found its way into several guidelines...
May 9, 2018: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/29742972/validity-and-clinical-utility-of-different-clock-drawing-test-scoring-systems-in-multiple-forms-of-dementia
#12
Diana Duro, Miguel Tábuas-Pereira, Sandra Freitas, Beatriz Santiago, Maria Amália Botelho, Isabel Santana
The Clock Drawing Test (CDT) has a known potential for the detection of cognitive impairment in populations with dementia, especially Alzheimer disease (AD). Our aim was to compare the clinical utility of 3 CDT scoring systems (Rouleau, Cahn, and Babins) in several pathologies with cognitive compromise from a tertiary center memory clinic. We selected patients with a clinical diagnosis of mild stage AD, behavioral variant frontotemporal dementia (FTD), vascular dementia (VaD), dementia with Lewy bodies (DLB), and Parkinson disease with dementia (PDD)...
January 1, 2018: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/29725946/spectrophotometric-photodynamic-diagnosis-of-prostate-cancer-cells-excreted-in-voided-urine-using-5-aminolevulinic-acid
#13
Yasushi Nakai, Makito Miyake, Satoshi Anai, Shunta Hori, Yoshihiro Tatsumi, Yosuke Morizawa, Sayuri Onisi, Nobumichi Tanaka, Kiyohide Fujimoto
To evaluate the feasibility of photodynamic diagnosis using 5-aminolevulinic acid (PDD-ALA) for detection of prostate cancer (PCa) cells in urine samples after prostate massage in patients who were suspected to have PCa. One hundred and eighty-nine patients with abnormal digital rectal examination and/or an elevated prostate-specific antigen (PSA) level who underwent initial prostate biopsy were recruited. After prostate massage, the first 60 mL of voided urine was collected. For PDD-ALA, 50 mL was used. The rest of collected urine was used for polymerase chain reaction (PCR) of PSA and glyceraldehyde 3-phosphate dehydrogenase (GAPDH)...
May 4, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29719283/performance-of-phonatory-deviation-diagrams-in-synthesized-voice-analysis
#14
Leonardo Wanderley Lopes, Karoline Evangelista da Silva, Deyverson da Silva Evangelista, Anna Alice Almeida, Priscila Oliveira Costa Silva, Jorge Lucero, Mara Behlau
OBJECTIVE: To analyze the performance of a phonatory deviation diagram (PDD) in discriminating the presence and severity of voice deviation and the predominant voice quality of synthesized voices. METHOD: A speech-language pathologist performed the auditory-perceptual analysis of the synthesized voice (n = 871). The PDD distribution of voice signals was analyzed according to area, quadrant, shape, and density. RESULTS: Differences in signal distribution regarding the PDD area and quadrant were detected when differentiating the signals with and without voice deviation and with different predominant voice quality...
May 2, 2018: Folia Phoniatrica et Logopaedica
https://www.readbyqxmd.com/read/29709507/anosognosia-for-cognitive-and-behavioral-symptoms-in-parkinson-s-disease-with-mild-dementia-and-mild-cognitive-impairment-frequency-and-neuropsychological-neuropsychiatric-correlates
#15
Maria Donata Orfei, Francesca Assogna, Clelia Pellicano, Francesco Ernesto Pontieri, Carlo Caltagirone, Mariangela Pierantozzi, Alessandro Stefani, Gianfranco Spalletta
INTRODUCTION: Anosognosia is a multidimensional phenomenon with detrimental effects on patients' illness course, therapy compliance and quality of life. We aimed at investigating anosognosia for cognitive and behavioral symptoms in Parkinson's Disease (PD) with dementia (PDD) and, for the first time, in PD with Mild Cognitive Impairment (MCI-PD). METHODS: Community dwelling subjects (47 mild PDD, 136 multidomain MCI-PD (mdMCI-PD), 5 single domain MCI-PD (sdMCI-PD), and 197 PD without cognitive impairment (noCI-PD) were enrolled in a cross-sectional design study...
April 17, 2018: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29705921/comparison-of-dsm-iv-tr-and-dsm-5-criteria-in-diagnosing-autism-spectrum-disorders-in-singapore
#16
Min Sung, Tze Jui Goh, Bei Lin Joelene Tan, Jialei Stephanie Chan, Hwee Sen Alvin Liew
Our study examines the Diagnostic and Statistical Manual-Fifth Edition (DSM-5) and Diagnostic and Statistical Manual-Fourth Edition, Text Revision (DSM-IV-TR) when applied concurrently against the best estimate clinical diagnoses for 110 children (5.1-19.6 years old) referred for diagnostic assessments of Autism Spectrum Disorder (ASD) in a Singaporean outpatient speciality clinic. DSM-IV-TR performed slightly better, yielding sensitivity of 0.946 and specificity of 0.889, compared to DSM-5 (sensitivity = 0...
April 28, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29701730/prevalence-of-autism-spectrum-disorder-among-children-aged-8-years-autism-and-developmental-disabilities-monitoring-network-11-sites-united-states-2014
#17
Jon Baio, Lisa Wiggins, Deborah L Christensen, Matthew J Maenner, Julie Daniels, Zachary Warren, Margaret Kurzius-Spencer, Walter Zahorodny, Cordelia Robinson Rosenberg, Tiffany White, Maureen S Durkin, Pamela Imm, Loizos Nikolaou, Marshalyn Yeargin-Allsopp, Li-Ching Lee, Rebecca Harrington, Maya Lopez, Robert T Fitzgerald, Amy Hewitt, Sydney Pettygrove, John N Constantino, Alison Vehorn, Josephine Shenouda, Jennifer Hall-Lande, Kim Van Naarden Braun, Nicole F Dowling
PROBLEM/CONDITION: Autism spectrum disorder (ASD). PERIOD COVERED: 2014. DESCRIPTION OF SYSTEM: The Autism and Developmental Disabilities Monitoring (ADDM) Network is an active surveillance system that provides estimates of the prevalence of autism spectrum disorder (ASD) among children aged 8 years whose parents or guardians reside within 11 ADDM sites in the United States (Arizona, Arkansas, Colorado, Georgia, Maryland, Minnesota, Missouri, New Jersey, North Carolina, Tennessee, and Wisconsin)...
April 27, 2018: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/29697716/prevalence-of-posterior-disc-displacement-of-the-temporomandibular-joint-in-patients-with-temporomandibular-disorders-systematic-review-and-meta-analyses
#18
Shaista Afroz, Mio Naritani, Hidehiko Hosoki, Kenshi Takechi, Yoshihiro Okayama, Yoshizo Matsuka
AIMS: To assess the prevalence of posterior disc displacement (PDD) in patients with temporomandibular disorders (TMD) through a systematic review of the literature and meta-analysis, as well as to assess features associated with PDD such as chief complaint, signs and symptoms, morphologic condyle and disc alterations, and PDD management. METHODS: A systematic literature search was performed in the US National Library of Medicine's PubMed/MEDLINE and Cochrane Library databases to identify all peer-reviewed, English-language manuscripts related to PDD...
April 25, 2018: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/29696741/outcomes-of-single-kidney-transplantation-from-pediatric-donors-a-single-center-experience
#19
Yamei Jiang, Turun Song, Yang Qiu, Jinpeng Liu, Zhiling Wang, Xianding Wang, Zhongli Huang, Yu Fan, Li Wang, Tao Lin
Kidneys from pDDs are increasingly used to narrow the huge gap between incremental demand and static supply. However, there is still controversy on the clinical outcome of SKT from pDDs. We conducted a retrospective cohort study of 452 adult recipients in our center between March 2012 and February 2017. Outcomes of 3 groups, transplants with organs from pDDs (n=50), aDDs (n=207), and LDs (n=195), were compared. The mean age and weight of pDDs were 8.98 years (range 8 months-17 years) and 30.05 kg (range 8...
April 25, 2018: Pediatric Transplantation
https://www.readbyqxmd.com/read/29665982/oscillatory-activity-and-cortical-coherence-of-the-nucleus-basalis-of-meynert-in-parkinson-s-disease-dementia
#20
Muhammad Nazmuddin, D L Marinus Oterdoom, J Marc C van Dijk, Jonathan C van Zijl, Anne K Kampman, Gea Drost, Teus van Laar, Martijn Beudel
BACKGROUND: Deep brain stimulation (DBS) of the nucleus basalis of Meynert (NBM) is a new potential treatment for Parkinson's Disease dementia (PDD) and other types of dementia. To get a better understanding of this structure, its local neurophysiological properties and cortical connectivity patterns were studied. METHODS: We simultaneously recorded DBS local field potentials (LFPs) and electroencephalography (EEG) in two patients with PDD. Both patients had DBS electrodes in the internal globus pallidus (GPi) with one or more distal contacts close to or inside the NBM...
March 28, 2018: Parkinsonism & related Disorders
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