Zeke Zamora, Li-Yung Lui, Lauren M Sparks, Jamie Justice, Mary Lyles, Landon Gentle, Heather Gregory, Reichelle X Yeo, Erin E Kershaw, Maja Stefanovic-Racic, Anne B Newman, Stephen Kritchevsky, Frederico G S Toledo
Biopsies of muscle and adipose tissue (AT) are useful tools to gain insights into the aging processes in these tissues. However, they are invasive procedures and their risk/benefit profile in older adults can be altered by sarcopenia, frailty, poor healing, and multimorbidity. Their success rates, safety, and tolerability in a geriatric population have not been reported in detail. Investigators in the Study of Muscle, Mobility, and Aging (SOMMA) performed biopsies of muscle and AT in older adults and prospectively collected data on biopsy success rates, safety, and tolerability...
February 5, 2024: GeroScience