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Degenerative scoliosis

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https://www.readbyqxmd.com/read/28443174/clinical-and-radiological-outcomes-after-microscopic-bilateral-decompression-via-a-unilateral-approach-for-degenerative-lumbar-disease-minimum-5-year-follow-up
#1
Sho Dohzono, Hiromitsu Toyoda, Akira Matsumura, Hidetomi Terai, Akinobu Suzuki, Hiroaki Nakamura
STUDY DESIGN: A retrospective study. PURPOSE: To assess postoperative bone regrowth at surgical sites after lumbar decompression with >5 years of follow-up. Postoperative preservation of facet joints and segmental spinal instability following surgery were also evaluated. OVERVIEW OF LITERATURE: Previous reports have documented bone regrowth after conventional laminectomy or laminotomy and several factors associated with new bone formation...
April 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/28437356/scoliosis-is-a-risk-factor-for-gastroesophageal-reflux-disease-in-adult-spinal-deformity
#2
Naobumi Hosogane, Kota Watanabe, Mitsuru Yagi, Shinjiro Kaneko, Yoshiaki Toyama, Morio Matsumoto
STUDY DESIGN: A prospective observational study. OBJECTIVE: To evaluate whether scoliosis is a risk factor for gastroesophageal reflux disease (GERD) in elderly patients. SUMMARY OF BACKGROUND DATA: Sagittal spinal deformities are reported to cause GERD, but its association with spinal deformity in the coronal plane is not well studied. METHODS: We examined 190 patients with spinal disorders (mean age 70.6±8.6 y) who underwent standing whole-spine x-rays in the coronal and sagittal planes...
May 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28435925/distal-junctional-failure-secondary-to-l5-vertebral-fracture-a-report-of-two-rare-cases
#3
Jiong Hao Tan, Kimberly-Anne Tan, Hwee Weng Dennis Hey, Hee-Kit Wong
Distal junctional failure (DJF) with fracture at the last instrumented vertebra is a rare occurrence. In this case report, we present two patients with L5 vertebral fracture post-instrumented fusion of the lumbar spine. The first patient is a 78-year-old female who had multi-level degenerative disc disease, spinal stenosis and degenerative scoliosis involving levels T12 to L5. She underwent instrumented posterolateral fusion (PLF) from T12 to L5, and transforaminal lumbar interbody fusion (TLIF) at L2/3 and L4/5...
March 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/28422833/correction-of-sagittal-imbalance-in-treatment-for-adult-degenerative-scoliosis-with-thoracic-lordosis-and-lumbar-kyphosis-a-case-report
#4
Tao Wang, Hui Wang, Lei Ma, Di Zhang, Wen-Yuan Ding
RATIONALE: Lumbar degenerative scoliosis (LDS) is a common spinal disease for senior citizens. However, LDS accompanied with thoracic lordosis and lumbar kyphosis (LK) is rare in clinic. No reports have reported LDS with thoracic lordosis and LK. PATIENT CONCERNS: A 54-year-old woman just complained about sever back pain without any radiculopathy and neurodeficit of low limb for 2 years, Visual Analogue Scale (VAS) for back pain was 9 points and x-ray showed adult LDS with lordosis angle of 10° from 5th thoracic to 12th thoracic (T5-T12) and LK angle of 20°...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28420247/clinical-and-radiological-outcomes-after-decompression-and-posterior-fusion-in-patients-with-degenerative-scoliosis
#5
Majid Reza Farrokhi, Mohammad Jamali, Mehrnaz Gholami, Farnaz Farrokhi, Khadijeh Hosseini
OBJECTIVE: The prevalence of degenerative scoliosis (DS) increases with age and an overall increase is seen due to the aging population. This study aims to evaluate the clinical and radiological outcomes after decompression and posterior fusion in patients with DS. METHODS: In this is prospective study, 43 patients with DS, aged 37 to 70 years, were eligible to undergo decompression and posterior fusion. Primary outcomes were low back pain (LBP) with or without radicular pain, which was evaluated preoperatively and at 12 and 24 months after surgery with the use of a visual analog scale (VAS), and the quality of life (QOL), which was assessed at the same time periods by the Oswestry Disability Index (ODI) questionnaire...
April 19, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/28416835/-polymethylmethacrylate-augmentation-of-bone-cement-injectable-cannulated-pedicle-screws-was-used-to-treat-degenerative-lumbar-scoliosis-with-osteoporosis
#6
H L Sun, C D Li, X W Li, X D Yi, H Liu, H L Lu, H Li, Z R Yu, Y Wang
OBJECTIVE: To describe the application of polymethylmethacrylate (PMMA) augmentation of cement-injectable cannulated pedicle screws for the treatment of degenerative lumbar scoliosis with osteoporosis. METHODS: Retrospective cohort study was used to compare cement injectable cannulated pedicle screws (CICPs) group with PMMA augmentation and control group with traditional method in the correction surgery for Lenke-silva level III and level IV degenerative scoliosis cases with osteoporosis...
April 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28399547/early-ambulation-decreases-length-of-hospital-stay-peri-operative-complications-and-improves-functional-outcomes-in-elderly-patients-undergoing-surgery-for-correction-of-adult-degenerative-scoliosis
#7
Owoicho Adogwa, Aladine A Elsamadicy, Jared Fialkoff, Joseph Cheng, Isaac O Karikari, Carlos Bagley
STUDY DESIGN: Ambispective cohort review. OBJECTIVE: To examine the effects of early mobilization on patient outcomes, complications profile and 30-day readmission rates. SUMMARY OF BACKGROUND DATA: Prolonged immobilization after surgery can result in functional decline and an increased risk of hospital-associated complications. METHODS: We conducted an ambispective study of 125 elderly patients (> 65 years old) undergoing elective spinal surgery for correction of adult degenerative scoliosis...
April 10, 2017: Spine
https://www.readbyqxmd.com/read/28392347/predictors-of-improvement-in-low-back-pain-after-lumbar-decompression-surgery-prospective-study-of-140-patients
#8
Hiroki Oba, Jun Takahashi, Takahiro Tsutsumimoto, Shota Ikegami, Hiroshi Ohta, Mutsuki Yui, Hidemi Kosaku, Takayuki Kamanaka, Hiromichi Misawa, Hiroyuki Kato
BACKGROUND: Lumbar decompression surgery is often used to treat neurological symptoms of the lower extremity as a result of lumbar disease. However, this method also leads to the improvement of the accompanying low back pain (LBP). We studied the extent of LBP improvement after lumbar decompression surgery without fusion and the associated preoperative factors. METHODS: Patients (n = 140) with lumbar spinal stenosis (n = 90) or lumbar disc herniation (n = 50) were included...
April 6, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28378072/interleukin-6-gene-polymorphism-in-patients-with-degenerative-lumbar-scoliosis-a-cohort-study
#9
Jung Sub Lee, Jong Ki Shin, Tae Sik Goh
PURPOSE: Low bone mass and a female gender increase susceptibility to the development of degenerative lumbar scoliosis (DLS), which suggests the potential involvement of an osteoporosis-related gene in the pathogenesis of DLS. In the present study, the authors studied the relations between polymorphisms of interleukin 6 (IL-6) gene and DLS in a patient cohort. METHODS: In 184 patients with a diagnosis of DLS, the authors determined the presence of the -597 G/A, -572 G/C, and -174 G/C polymorphisms, measured bone mineral densities at the lumbar spine (LSBMD) and femoral neck (FNBMD), assessed radiological findings including lumbar scoliosis and lateral listhesis, investigated biochemical markers of bone turnover, and compared these results obtained with those of 220 healthy normal controls...
April 4, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28365496/optimum-pelvic-incidence-minus-lumbar-lordosis-value-after-operation-for-patients-with-adult-degenerative-scoliosis
#10
Xiang-Yao Sun, Xi-Nuo Zhang, Yong Hai
BACKGROUND CONTEXT: Schwab classification for adult degenerative scoliosis (ADS) concluded that health-related quality of life (HRQOL) was closely related to curve type and three sagittal modifiers. It was suggested that pelvic incidence minus lumbar lordosis value (PI-LL) should be corrected within -10°~+10°. However, recent studies also indicated that ideal clinical outcomes could also be achieved in patients without ideal PI-LL mentioned above. PURPOSE: This study evaluated the relation between the clinical outcomes and the pelvic incidence minus lumbar lordosis value (PI-LL) of Chinese patients with ADS who received long posterior internal fixation and fusion...
March 29, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28362970/commentary-appropriate-use-criteria-for-lumbar-degenerative-scoliosis-developing-evidence-based-guidance-for-complex-treatment-decisions
#11
Steven D Glassman, Sigurd H Berven, Christopher I Shaffrey, Praveen V Mummaneni, David W Polly
Lumbar degenerative scoliosis is a relatively common problem, and is being treated more frequently due to the confluence of an aging population and an increased capacity and willingness to manage difficult problems in older patients. Lumbar degenerative scoliosis is a complex pathology as it often involves the intersection of degenerative spinal stenosis and spinal deformity. While previous studies provide an indication that these patients may benefit from surgical treatment, the substantial variability in treatment underscores the opportunity for improvement...
March 1, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28356146/do-the-disc-degeneration-and-osteophyte-contribute-to-the-curve-rigidity-of-degenerative-scoliosis
#12
Feng Zhu, Hongda Bao, Peng Yan, Shunan Liu, Mike Bao, Zezhang Zhu, Zhen Liu, Yong Qiu
BACKGROUND: The factors associated with lateral curve flexibility in degenerative scoliosis have not been well documented. Disc degeneration could result in significant change in stiffness and range of motion in lateral bending films. The osteophytes could be commonly observed in degenerative spine but the relationship between osteophyte formation and curve flexibility remains controversial. The aim of the current study is to clarify if the disc degeneration and osteophyte formation were both associated with curve flexibility of degenerative scoliosis...
March 29, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28342408/finite-element-method-based-study-for-effect-of-adult-degenerative-scoliosis-on-the-spinal-vibration-characteristics
#13
Ming Xu, James Yang, Isador Lieberman, Ram Haddas
Finite element analysis was used to investigate the responses of five healthy subjects and five adult degenerative scoliosis (ADS) subjects to cyclic vibration. The dynamic responses of the healthy and scoliotic spines to the sinusoidal cyclic vibrations have been investigated in previous studies by simulation or experimental approaches. However, no simulation or experimental results were available for the ADS subjects. The effect of the ADS on the vibrational characteristics of spines remained unknown. The objective of this study was to compare differences of the dynamic responses to the cyclic vibration input between the healthy subjects and subjects with ADS...
March 22, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28331906/associations-between-sarcopenia-and-degenerative-lumbar-scoliosis-in-older-women
#14
Yawara Eguchi, Munetaka Suzuki, Hajime Yamanaka, Hiroshi Tamai, Tatsuya Kobayashi, Sumihisa Orita, Kazuyo Yamauchi, Miyako Suzuki, Kazuhide Inage, Kazuki Fujimoto, Hirohito Kanamoto, Koki Abe, Yasuchika Aoki, Tomoaki Toyone, Tomoyuki Ozawa, Kazuhisa Takahashi, Seiji Ohtori
BACKGROUND: Age-related sarcopenia can cause various forms of physical disabilities. We investigated how sarcopenia affects degenerative lumbar scoliosis (DLS) and lumbar spinal canal stenosis (LSCS). METHODS: Subjects comprised 40 elderly women (mean age 74 years) with spinal disease whose chief complaints were low back pain and lower limb pain. They included 15 cases of DLS (mean 74.8 years) and 25 cases of LSCS (mean age 72.9 years). We performed whole-body dual-energy X-ray absorptiometry (DXA) to analyze body composition, including appendicular and trunk skeletal muscle mass index (SMI; lean mass (kg)/height (m)(2)) and bone mineral density (BMD)...
2017: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/28228325/prognostic-factors-associated-with-the-surgical-indication-for-lumbar-spinal-stenosis-patients-less-responsive-to-conservative-treatments-an-investigator-initiated-observational-cohort-study
#15
Masayoshi Fukushima, Hiroyuki Oka, Nobuhiro Hara, Yasushi Oshima, Hirotaka Chikuda, Sakae Tanaka, Katsushi Takeshita, Ko Matsudaira
BACKGROUND: A few cohort studies have determined which patients with lumbar spinal stenosis are likely to need surgery because of the deterioration of symptoms. However, there are still insufficient data regarding the management of lumbar spinal stenosis due to lack of prognostic factors associated with the need for surgery. The purpose of this study was to identify the prognostic factors associated with the need for surgical treatment in patients with lumbar spinal stenosis. METHODS: Patients with lumbar spinal stenosis from our hospital and related facilities were enrolled...
February 19, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28224704/advanced-glycation-end-products-regulate-anabolic-and-catabolic-activities-via-nlrp3-inflammasome-activation-in-human-nucleus-pulposus-cells
#16
Yu Song, Yan Wang, Yukun Zhang, Wen Geng, Wei Liu, Yong Gao, Shuai Li, Kun Wang, Xinghuo Wu, Liang Kang, Cao Yang
Intervertebral disc degeneration is widely recognized as a cause of lower back pain, neurological dysfunction and other musculoskeletal disorders. The major inflammatory cytokine IL-1β is associated with intervertebral disc degeneration; however, the molecular mechanisms that drive IL-1β production in the intervertebral disc, especially in nucleus pulposus (NP) cells, are unknown. In some tissues, advanced glycation end products (AGEs), which accumulate in NP tissues and promote its degeneration, increase oxidative stress and IL-1β secretion, resulting in disorders, such as obesity, diabetes mellitus and ageing...
February 22, 2017: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/28207622/curve-characteristics-and-foraminal-dimensions-in-patients-with-adult-scoliosis-and-radiculopathy
#17
Andrew J Pugely, Zachary Ries, Gnanapradeep Gnanapragasam, Yubo Gao, Rachel Nash, Sergio A Mendoza-Lattes
STUDY DESIGN: Retrospective cohort study. OBJECTIVE: To demonstrate a correlation between radiculopathy symptoms, foraminal morphology, and curve types. SUMMARY OF BACKGROUND DATA: Patients with degenerative scoliosis frequently present with foraminal stenosis and radiculopathy, the origin of which is not well understood. METHODS: A total of 48 patients (384 foraminas) were included: 14 with low back pain (B); 16 with femoral nerve pain (F); and 18 with sciatic nerve pain (S)...
March 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28193137/risk-factors-for-adjacent-segment-degeneration-after-iliac-screw-fixation-in-lumbar-degenerative-kyphoscoliosis
#18
Sang-Il Kim, Kee-Yong Ha, Dong-Whan Suh, In-Soo Oh
PURPOSE: To analyze pre- and postoperative spinopelvic parameters and sagittal profiles in lumbar degenerative kyphoscoliosis (LDK) patients who underwent surgery using iliac screw (IS) and the incidence and risk factor of radiological adjacent segment degeneration (ASD). METHODS: A total of 32 patients, who had undergone surgical correction and lumbar/thoracolumbar fusion with pedicle screws and IS instrumentation for LDK with a minimum 2-year follow-up, were included...
January 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28180982/surgical-treatment-of-thoraco-lumbar-kyphosis-tlk-associated-with-low-pelvic-incidence
#19
C Scemama, F Laouissat, K Abelin-Genevois, P Roussouly
PURPOSE: Thoraco-lumbar kyphosis (TLK) is poorly described in the literature and its surgical treatment remains equivocal for patients with low pelvic incidence. The aim of the study was to identify which surgical correction would yield the best functional results as measured by the Oswestry score. MATERIALS AND METHODS: This is a retrospective study including patients described as a type 1 of Roussouly's classification with a thoraco-lumbar kyphosis. Fifty-six patients with degenerative spinal disease were included, 42 (75%) with scoliosis and 14 (25%) without...
February 8, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28161236/minimally-invasive-decompression-surgery-for-lumbar-spinal-stenosis-with-degenerative-scoliosis-predictive-factors-of-radiographic-and-clinical-outcomes
#20
Akihito Minamide, Munehito Yoshida, Hiroki Iwahashi, Andrew K Simpson, Hiroshi Yamada, Hiroshi Hashizume, Yukihiro Nakagawa, Hiroshi Iwasaki, Shunji Tsutsui, Ryohei Kagotani, Mayumi Sonekatsu, Takahide Sasaki, Kazunori Shinto, Tsuyoshi Deguchi
There is ongoing controversy regarding the most appropriate surgical treatment for lumbar spinal stenosis (LSS) with concurrent degenerative lumbar scoliosis (DLS): decompression alone, decompression with limited spinal fusion, or long spinal fusion for deformity correction. The coexistence of degenerative stenosis and deformity is a common scenario; Nonetheless, selecting the appropriate surgical intervention requires thorough understanding of the patients clinical symptomatology as well as radiographic parameters...
February 1, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
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