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https://www.readbyqxmd.com/read/29781852/the-effect-of-postmastectomy-radiation-therapy-on-breast-implants-material-analysis-on-silicone-and-polyurethane-prosthesis
#1
Federico Lo Torto, Michela Relucenti, Giuseppe Familiari, Nicola Vaia, Donato Casella, Roberto Matassa, Selenia Miglietta, Franco Marinozzi, Fabiano Bini, Ilaria Fratoddi, Fabio Sciubba, Raffaele Cassese, Vincenzo Tombolini, Diego Ribuffo
INTRODUCTION: The pathogenic mechanism underlying capsular contracture is still unknown. It is certainly a multifactorial process, resulting from human body reaction, biofilm activation, bacteremic seeding, or silicone exposure. The scope of the present article is to investigate the effect of hypofractionated radiotherapy protocol (2.66 Gy × 16 sessions) both on silicone and polyurethane breast implants. METHODS: Silicone implants and polyurethane underwent irradiation according to a hypofractionated radiotherapy protocol for the treatment of breast cancer...
May 17, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29780909/disseminated-silicone-granulomatosis-in-the-face-and-orbit
#2
Tiffany A Chen, Carmel L Mercado, Katie L Topping, Benjamin P Erickson, Kimberly P Cockerham, Andrea L Kossler
Purpose: To report a case of disseminated silicone granulomatosis presenting with ptosis, proptosis and vision loss. Observations: A 56-year-old female presented with ptosis, proptosis, and vision loss and was noted to have palpable, erythematous masses involving the orbit, face, trunk, and body. She had a history of bilateral silicone breast implants and cosmetic facial filler injections. Orbital biopsy demonstrated non-caseating granulomas with foreign-body giant cells and vacuoles containing material consistent with silicone...
June 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29780717/robotic-internal-mammary-lymphadenectomy-another-possible-minimally-invasive-approach-to-sampling-lymph-nodes-in-breast-cancer-patients
#3
Alessandro Pardolesi, Luca Bertolaccini, Jury Brandolini, Piergiorgio Solli
Internal mammary lymphadenopathy may develop in breast cancer patients with silicone implants. Differential diagnosis includes malignant recurrence, infections, inflammations and granulomatous deposit. We report a case of internal mammary lymphadenopathy, in a patient with the previous history of breast cancer, requiring a tissue diagnosis. We performed a Robotic lymph nodes dissection of the left internal mammary. Final pathology diagnosis was positive for silicone granulomatous lymphadenitis secondary to silicone breast implants inserted after mastectomy for breast cancer...
2018: Journal of Visualized Surgery
https://www.readbyqxmd.com/read/29750759/immediate-two-stage-prosthetic-breast-reconstruction-failure-radiation-is-not-the-only-culprit
#4
Thomas C Lam, Robert Borotkanics, Frank Hsieh, James Salinas, John Boyages
BACKGROUND: Immediate prosthetic breast reconstruction produces a satisfactory aesthetic result with high levels of patient satisfaction. However, with the broader indication for post-mastectomy adjuvant radiation, many patients are advised against immediate breast reconstruction because of concerns of implant loss and infection particularly as most patients also require chemotherapy. This retrospective cohort study examines outcomes for patients who underwent immediate two-stage prosthetic breast reconstruction after mastectomy with or without adjuvant chemotherapy or radiotherapy (RT)...
March 15, 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29741418/the-effect-of-sio-2-au-core-shell-nanoparticles-on-breast-cancer-cell-s-radiotherapy
#5
Ghazal Darfarin, Roya Salehi, Effat Alizadeh, Behnam Nasiri Motlagh, Abolfazl Akbarzadeh, Alireza Farajollahi
INTRODUCTION: Recently it has been shown that radiation dose enhancement could be achievable in radiotherapy using nanoparticles (NPs). In this study, evaluation was made to determine efficiency of gold-silica shell-core NP in megavoltage irradiation of MCF7 breath cancer cells. MATERIALS AND METHODS: Gold-silicon oxide shell-core NPs were obtained by conjugation of gold NP with amine or thiol functionalized silica NPs (AuN@SiO2 and AuS@SiO2 ). Cellular uptake and cytotoxicity of NPs were examined by fluorescent microscopy and MTT assay, respectively...
May 9, 2018: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/29736283/chronic-pulmonary-silicone-embolism-from-breast-augmentation-is-not-a-common-finding-in-explanted-lungs
#6
Jarmanjeet Singh, Hanine Inaty, Sanjay Mukhopadhyay, Atul C Mehta
Objective: Acute pulmonary silicone embolism (APSE) related to subcutaneous silicone injections is a well-known entity. Recently, a few cases of pathologically confirmed chronic pulmonary silicone embolism (CPSE) from breast implants have been reported. The prevalence of CPSE in women with breast augmentation is unknown. This study was done to determine the prevalence of CPSE in female lung transplant recipients with a history of breast augmentation and to determine whether breast augmentation plays a role in chronic lung diseases requiring lung transplantation...
2018: Pulmonary Medicine
https://www.readbyqxmd.com/read/29724416/acr-appropriateness-criteria-%C3%A2-breast-implant-evaluation
#7
Ana P Lourenco, Linda Moy, Paul Baron, Aarati D Didwania, Roberta M diFlorio, Samantha L Heller, Anna I Holbrook, Alana A Lewin, Tejas S Mehta, Bethany L Niell, Priscilla J Slanetz, Ashley R Stuckey, Daymen S Tuscano, Nina S Vincoff, Susan P Weinstein, Mary S Newell
Breast implant imaging varies depending on patient age, implant type, and symptoms. For asymptomatic patients (any age, any implant), imaging is not recommended. Rupture of saline implants is often clinically evident, as the saline is resorbed and there is a change in breast contour. With saline implants and equivocal clinical findings, ultrasound (US) is the examination of choice for patients less than 30 years of age, either mammography/digital breast tomosynthesis or US may be used for those 30 to 39 years of age, and mammography/digital breast tomosynthesis is used for those 40 years and older...
May 2018: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29718087/physical-properties-of-silicone-gel-breast-implants
#8
Mark L Jewell, Bradley P Bengtson, Kate Smither, Gina Nuti, TracyAnn Perry
Background: Surgical applications using breast implants are individualized operations to fill and shape the breast. Physical properties beyond shape, size, and surface texture are important considerations during implant selection. Objective: Compare form stability, gel material properties, and shell thickness of textured shaped, textured round, and smooth round breast implants from 4 manufacturers: Allergan, Mentor, Sientra, and Establishment Labs through bench testing...
April 28, 2018: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29714655/localized-morphea-after-breast-implant-for-breast-cancer-a-case-report
#9
A Moretti, F Bianchi, I V Abbate, G Gherardi, M Bonavita, E Passoni, G Nazzaro, A Bramati, M C Dazzani, S Piva, E Paternò, N Frungillo, G Farina, N La Verde
PURPOSE: Early breast cancer follow-up guidelines for patients who underwent surgery suggest a regular and accurate clinical examination of the breast area, for an early identification of cutaneous or subcutaneous breast cancer relapse. Nonetheless, breast skin lesions arising in patients treated with mastectomy for breast cancer can be caused by several diseases. A series of diagnostic hypotheses should be considered, not only focusing on cutaneous metastasis, but also on dermatologic and systemic diseases...
March 1, 2018: Tumori
https://www.readbyqxmd.com/read/29707469/creation-of-a-central-under-flap-pocket-allows-secondary-implant-augmentation-of-perforator-flap-breast-reconstruction
#10
Craig A Blum, Frank J DellaCroce, Scott K Sullivan, Chris Trahan, M Whitten Wise
Background: When a single perforator flap does not provide adequate volume or projection for satisfactory breast reconstruction, the addition of an implant may be considered at the time of second-stage revisions. Dissection of an implant pocket beneath the flap may lead to the inadvertent injury of the flap pedicle as the tissue planes have been obscured by tissue ingrowth. The authors present a technique in which the boundaries of the implant pocket are predetermined at the time of flap reconstruction allowing an implant to be inserted at the second stage in ideal position with greater ease of dissection and minimal risk to the flap pedicle...
March 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29697611/discussion-consequences-of-the-u-s-food-and-drug-administration-directed-moratorium-on-silicone-gel-breast-implants-1992-to-2006
#11
Jack C Fisher
No abstract text is available yet for this article.
May 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29697610/consequences-of-the-u-s-food-and-drug-administration-directed-moratorium-on-silicone-gel-breast-implants-1992-to-2006
#12
Norman M Cole
The U.S. Food and Drug Administration silicone gel breast implant moratorium occurred 25 years ago. The immediate and long-term consequences of the moratorium are reviewed and assessed.
May 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29692660/the-satisfaction-of-patients-with-breast-cancer-undergone-immediate-reconstruction-with-implant-and-the-effect-of-radiotherapy
#13
Ayse Y Altinok, Nuran Bese, Halil Kara, Sukru Yazar, Cihan Unal
Aim of the study: Postmastectomy reconstructive surgery for cosmetic satisfaction of patients is rapidly increasing. Postoperative complications such as infection, capsular contracture, implant loss are more common in patients who receive adjuvant radiotherapy (RT) than those who do not. Satisfaction levels in patients is still a controversial issue. Therefore, we wanted to investigate our patient population for the effects of RT and planned a study evaluating the satisfaction rates of our patients who received implants...
2018: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/29684623/decoration-of-rgd-mimetic-porous-scaffolds-with-engineered-and-devitalized-extracellular-matrix-for-adipose-tissue-regeneration
#14
Eleonora Rossi, Julien Guerrero, Paola Aprile, Alessandro Tocchio, Elisabeth A Kappos, Cristina Lenardi, Ivan Martin, Arnaud Scherberich
Fat grafting is emerging as a promising alternative to silicon implants in breast reconstruction surgery. Unfortunately, this approach does not provide a proper mechanical support and is affected by drawbacks such as tissue resorption and donor site morbidity. Synthetic scaffolds can offer a valuable alternative to address these challenges, but poorly recapitulate the biochemical stimuli needed for tissue regeneration. Here, we aim at combining the positive features of a structural, synthetic polymer to an engineered, devitalized extracellular matrix (ECM) to generate a hybrid construct that can provide a mix of structural and biological stimuli needed for adipose tissue regeneration...
April 20, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29680487/spectrum-of-chronic-complications-related-to-silicone-leakage-and-migration
#15
Alexander J Ryu, Katrina N Glazebrook, Naziya Samreen, Philippe R Bauer, Eunhee S Yi, Jay H Ryu
BACKGROUND: Medical silicone is widely used as implants and free injections but the spectrum of complications related to migration or embolization of silicone remains unclear. METHODS: We retrospectively reviewed 79 patients with silicone migration as confirmed on pathology between January 1, 2001 and December 31, 2016. The presenting clinical and imaging features, diagnostic testing, treatment, and outcome were assessed. RESULTS: Nearly all were women and 43% had a history of breast cancer...
April 19, 2018: American Journal of Medicine
https://www.readbyqxmd.com/read/29663703/cytological-features-of-breast-peri-implant-papillary-synovial-metaplasia
#16
José A Jiménez-Heffernan, Carmen Bárcena, Patricia Muñoz-Hernández
Synovial metaplasia is a peculiar form of metaplasia seen in the inner lining of the fibrous capsule that surrounds breast implants. Since the description of breast-implant associated anaplastic large cell lymphoma it is increasingly common to receive periprosthetic breast fluid collections for pathologic analysis. We describe a case of breast-implant papillary synovial metaplasia that showed remarkable cytologic findings. A review of the medical literature revealed one previous cytologic description. The patient, A 53-year-old woman underwent surgery because of capsular contracture of textured, silicone breast implants...
April 16, 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29659713/primary-squamous-cell-carcinoma-arising-from-a-breast-implant-capsule-a-case-report-and-review-of-the-literature
#17
Patrick J Buchanan, Vinod K Chopra, Kristen L Walker, Ray Rudolph, Richard J Greco
Squamous cell carcinoma (SCC) arising from the breast is an exceedingly rare disease; even more rare is SCC arising from a breast implant capsule. So far, only five cases have been reported in the literature. We present the case of a 65-year-old woman with a remote history of breast augmentation using foam covered silicone implants performed in 1979. In 2010, she presented with progressive enlargement of her left breast with associated pain. Mammographic and sonographic evaluation demonstrated fluid surrounding the implant without evidence of abnormal masses...
April 6, 2018: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29658786/imaging-findings-of-mammary-and-systemic-silicone-deposition-secondary-to-breast-implants
#18
Naziya Samreen, Katrina N Glazebrook, Asha Bhatt, Sudhakar K Venkatesh, Brendan P McMenomy, Anupam Chandra, Shuai Ieng, Kalie E Adler, Cynthia H McCollough
In patients with silicone breast implants, implant rupture can occur, which can be intracapsular or extracapsular. Following implant rupture, silicone can travel through the lymphatic system into regional and distant lymph nodes. The purpose of this pictorial essay is to present findings of silicone implant rupture with intramammary and systemic silicone deposition as seen on dual energy CT (DECT), US, mammogram, PET/CT and MRI. We include imaging findings of silicone deposition in the breast in cases of intracapsular and extracapsular rupture...
April 16, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29649133/current-approaches-including-novel-nano-microtechniques-to-reduce-silicone-implant-induced-contracture-with-adverse-immune-responses
#19
REVIEW
Shin Hyuk Kang, Chanutchamon Sutthiwanjampa, Chan Young Heo, Woo Seob Kim, Soo-Hong Lee, Hansoo Park
Capsular contracture, which is the pathologic development of fibrous capsules around implants, is a major complication of reconstructive and aesthetic breast surgeries. Capsular contracture can cause implant failure with breast hardening, deformity, and severe pain. The exact mechanisms underlying this complication remain unclear. In addition, anaplastic large cell lymphoma is now widely recognized as a very rare disease associated with breast implants. Foreign body reactions are an inevitable common denominator of capsular contracture...
April 12, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29628636/bismuth-silicon-and-bismuth-polyurethane-composite-shields-for-breast-protection-in-chest-computed-tomography-examinations
#20
Parinaz Mehnati, Mehran Arash, Parisa Akhlaghi
The article aims at constructing protective composite shields for breasts in chest computed tomography and investigating the effects of applying these new bismuth composites on dose and image quality. Polyurethane and silicon with 5% of bismuth were fabricated as a protective shield. At first, their efficiency in attenuating the X-ray beam was investigated by calculating the total attenuation coefficients at diagnostic energy range. Then, a physical chest phantom was scanned without and with these shields at tube voltage of 120 kVp, and image parameters together with dose values were studied...
January 2018: Journal of Medical Physics
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