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https://www.readbyqxmd.com/read/28236798/adherence-and-safety-study-in-patients-on-treatment-with-capecitabine
#1
Francisca Fernández-Ribeiro, Rosario Olivera-Fernández, Carlos Crespo-Diz
BACKGROUND: The introduction of oral antineoplastic agents in therapeutics has caused a change in the treatment strategy against cancer. The objective of this study was to analyze the adherence in patients to treatment with capecitabine, their adverse events, and the overall health status of patients, as well as the relationship of these factors with adherence. METHOD: An observational, prospective study at 7 months, in a cohort of patients on capecitabine treatment, including treatment initiations and continuations, regardless of diagnosis or indication...
March 1, 2017: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/28216833/silicone-breast-implants-and-echocardiographic-interactions-a-brand-new-study
#2
Roberto Cuomo, Giuseppe Nisi, Luca Grimaldi, Cesare Brandi, Carlo D'Aniello
No abstract text is available yet for this article.
September 2016: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/28186859/multimodality-imaging-based-evaluation-of-single-lumen-silicone-breast-implants-for-rupture
#3
Stephen J Seiler, Pooja B Sharma, Jody C Hayes, Ramapriya Ganti, Ann R Mootz, Emily D Eads, Sumeet S Teotia, W Phil Evans
Breast implants are frequently encountered on breast imaging studies, and it is essential for any radiologist interpreting these studies to be able to correctly assess implant integrity. Ruptures of silicone gel-filled implants often occur without becoming clinically obvious and are incidentally detected at imaging. Early diagnosis of implant rupture is important because surgical removal of extracapsular silicone in the breast parenchyma and lymphatics is difficult. Conversely, misdiagnosis of rupture may prompt a patient to undergo unnecessary additional surgery to remove the implant...
February 10, 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28175968/augmentation-of-the-nipples-reconstructed-with-modified-top-hat-flap-using-dermal-grafts-in-implant-based-breast-reconstruction-a-comparative-study
#4
Hoon Kim, Sang Il Kim, Won Ha, Chi Sun Yoon, Taik Jong Lee, Kyu Nam Kim
BACKGROUND: Nipple reconstruction in implant-based breast reconstruction remains challenging, as the remaining thin skin envelope results in a less projected neo-nipple with a reduced volume. This study presents a modified top-hat flap technique with rolled dermal grafts from the dog-ears of lateral wings for augmenting reconstructed nipples during implant-based breast reconstruction. METHODS: Between April 2011 and December 2014, among 34 patients who underwent immediate post-mastectomy reconstruction with a direct silicone implant, nipple reconstruction was performed using the modified top-hat flap technique in only 21 patients (group A), whereas 13 patients underwent the modified top-hat flap technique with rolled dermal grafts from the dog-ears of lateral wings (group B)...
February 7, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28160072/systemic-sclerosis-with-anti-rna-polymerase-iii-positivity-following-silicone-breast-implant-rupture-possible-role-of-b-cell-depletion-and-implant-removal-in-the-treatment
#5
REVIEW
Francesca Dall'Ara, Maria-Grazia Lazzaroni, Chiara M Antonioli, Paolo Airò
Despite some case reports and small series of women with silicone breast implants (SBI) developing Systemic Sclerosis (SSc), no clear evidence of an association of SBI with SSc is available. However, SSc is characterized by clinical and immunological heterogeneity and autoantibodies are currently the best markers to stratify this heterogeneity of patients. Therefore, we have reviewed the literature for details of autoantibody characterization in reports of SSc associated with SBI. Moreover, the case of an anti-RNA polymerase III-positive SSc with rapid onset and progression, in which SBI rupture was found is described...
February 3, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28134037/destiny-rides-again-the-reappearance-of-silicone-gel-filled-breast-implant-toxicity
#6
A E Brawer
Background Twenty-five years ago attorneys representing ailing women in class action litigation against silicone breast implant manufacturers made the procedural error of defining silicone-induced toxicity in the courtroom before it was properly studied in the exam room. This aberrant methodology perverted the proper research process, rendered verification of any real disease elusive, and cemented the groundwork for a repeat public health crisis potentially affecting two million women in the USA who possess new silicone gel devices inserted over the past 10 years...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28096110/bra-sizing-and-the-plastic-surgery-herd-effect-are-breast-augmentation-patients-getting-accurate-information
#7
Christopher R Costa, Kevin H Small, William P Adams
BACKGROUND: Bra sizing is a common method to preoperatively select implants for breast augmentation; however, no series has analyzed the accuracy of this modality postoperatively. Alternatively, previous investigations have validated the accuracy and utility of three-dimensional (3D) imaging for preoperative simulation in breast augmentation. OBJECTIVES: This investigation utilizes 3D analysis to determine if preoperative bra sizing provides equivocal information compared to surgical 3D simulation for patient education and planning prior to a breast augmentation...
January 17, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28072394/three-dimensional-cascaded-system-analysis-of-a-50-%C3%A2%C2%B5m-pixel-pitch-wafer-scale-cmos-active-pixel-sensor-x-ray-detector-for-digital-breast-tomosynthesis
#8
C Zhao, N Vassiljev, A C Konstantinidis, R D Speller, J Kanicki
High-resolution, low-noise x-ray detectors based on the complementary metal-oxide-semiconductor (CMOS) active pixel sensor (APS) technology have been developed and proposed for digital breast tomosynthesis (DBT). In this study, we evaluated the three-dimensional (3D) imaging performance of a 50 µm pixel pitch CMOS APS x-ray detector named DynAMITe (Dynamic Range Adjustable for Medical Imaging Technology). The two-dimensional (2D) angle-dependent modulation transfer function (MTF), normalized noise power spectrum (NNPS), and detective quantum efficiency (DQE) were experimentally characterized and modeled using the cascaded system analysis at oblique incident angles up to 30°...
March 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28068732/-concept-for-a-national-implant-registry-to-improve-patient-safety
#9
L Prantl, U von Fritschen, J Liebau, J von Hassel, E M Baur, P M Vogt, R E Giunta, R E Horch
Since the introduction of silicone implants, several events have led to considerable uncertainty among the patients, public, and users. So far, however, the necessary steps to significantly improving patient safety have not been taken in any of these cases. Requiring stricter approvals for medical devices, improving monitoring by the regulatory authorities and the revision of the Medical Devices Directive are all initial steps in the right direction towards a change in policy, but are insufficient as an early warning system...
December 2016: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/28032163/transition-from-round-to-shaped-implants-in-immediate-breast-reconstruction-our-preferred-approach-and-clinical-outcomes
#10
Thomas A Imahiyerobo, Kevin H Small, Robyn Sackeyfio, Hannah Hoffman, Mia Talmor
BACKGROUND: Smooth, round, silicone implants predominate device-based breast reconstruction in the USA; despite their prevalence, complications can include bottoming out, superior contour deformity, rippling, and/or lateral malposition. This complication profile increases the need for revision surgery and subsequent patient dissatisfaction. With the resurgence of shaped, textured, silicone implants in the USA, we report the senior author's success with these devices and outline a strategy to optimize outcomes in breast reconstruction surgery...
December 28, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28027218/discussion-risk-factor-analysis-for-capsular-contracture-malposition-and-late-seroma-in-subjects-receiving-natrelle-410-form-stable-silicone-breast-implants
#11
Joseph J Disa
No abstract text is available yet for this article.
January 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27943644/quercetin-based-modified-porous-silicon-nanoparticles-for-enhanced-inhibition-of-doxorubicin-resistant-cancer-cells
#12
Zehua Liu, Vimalkumar Balasubramanian, Chinmay Bhat, Mikko Vahermo, Ermei Mäkilä, Marianna Kemell, Flavia Fontana, Agne Janoniene, Vilma Petrikaite, Jarno Salonen, Jari Yli-Kauhaluoma, Jouni Hirvonen, Hongbo Zhang, Hélder A Santos
One of the most challenging obstacles in nanoparticle's surface modification is to achieve the concept that one ligand can accomplish multiple purposes. Upon such consideration, 3-aminopropoxy-linked quercetin (AmQu), a derivative of a natural flavonoid inspired by the structure of dopamine, is designed and subsequently used to modify the surface of thermally hydrocarbonized porous silicon (PSi) nanoparticles. This nanosystem inherits several advanced properties in a single carrier, including promoted anticancer efficiency, multiple drug resistance (MDR) reversing, stimuli-responsive drug release, drug release monitoring, and enhanced particle-cell interactions...
December 12, 2016: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/27940906/unraveling-factors-influencing-early-seroma-formation-in-breast-augmentation-surgery
#13
Marcos Sforza, Rodwan Husein, Connor Atkinson, Renato Zaccheddu
BACKGROUND: It is often assumed that seroma formation trails closely behind with incidence rates reported at 1 to 2%. Seroma is highly problematic for both the surgeon and patient and results in both patient anxiety and discomfort, succeeded by frequent outpatient visits, follow-up treatment, increased costs, and potentially hampered aesthetic outcomes. Consequently, it is now more important than ever to study seroma and to assess its pathophysiology and mechanisms of prevention. OBJECTIVES: The aim of this study was to isolate and identify risk factors that may be associated with early seroma formation...
December 9, 2016: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/27894917/incidence-of-breast-implant-rupture-in-a-12-year-retrospective-cohort-evidence-of-quality-discrepancy-depending-on-the-range
#14
Frédéric Seigle-Murandi, François Lefebvre, Catherine Bruant-Rodier, Frédéric Bodin
BACKGROUND & OBJECTIVE: The majority of studies assessing the rupture rate of breast implants were performed by the breast implant manufacturing industry with questionable independence. After repetitive removals of ruptured implants from the same model, our team decided to assess the rupture rate and the estimated risk thereof for most of the silicone gel-filled implants we have used since they regained market approval in France in 2001. METHODS: Our study is a retrospective cohort of 809 patients operated in our University Hospital from 2001 to 2013 for cosmetic or reconstructive goals...
January 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/27884086/predictors-of-satisfaction-in-patient-with-silicone-breast-implants-and-its-association-with-drug-intake-habits
#15
Inês Correia-Sá, M Natália D S Cordeiro, José Amarante, Marisa Marques
BACKGROUND: Satisfaction is an important outcome variable in surgical success. The purpose of this study is to evaluate predictors of satisfaction in women submitted to silicone textured breast implant surgery. METHODS: A retrospective evaluation of women receiving textured silicone breast implants was performed. Patients were divided in four groups: cosmetic cohort (n = 104), reconstructive cohort (n = 120), general population control cohort (n = 120) and aesthetic control cohort (n = 54)...
November 24, 2016: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/27873527/numerical-evaluation-of-scar-after-breast-reconstruction-with-abdominal-advancement-flap
#16
M Kovář, L Čapek, L Vítová, M Molitor
BACKGROUND: The treatment of breast cancer has developed a lot during the last decade, nevertheless it still remains a considerable social and economical problem all over the world. The choice of the surgical procedure depends on a patients protocol and the surgeons preferences. The aim of this study is to evaluate the stress on the scar after breast reconstruction. METHODS: Mathematical modeling of the sutured skin flap used for breast implant placement was divided into the following two steps...
2016: Acta Chirurgiae Plasticae
https://www.readbyqxmd.com/read/27836857/role-of-macrotextured-shaped-extra-full-projection-cohesive-gel-implants-in-primary-aesthetic-breast-augmentation
#17
Paolo Montemurro, Mubashir Cheema, Per Hedén, Massimiliano Ferri, Alessandro Quattrini Li, Stefano Avvedimento
BACKGROUND: Extra full projection implants are used in a select group of aesthetic breast surgery patients. Their use is selective enough that they have not been included in long term manufacturer studies and the indications for their use have attracted much debate. Only a handful of studies have reported the outcomes from implantation of these devices. OBJECTIVES: We review our experience of using extra full projection anatomically shaped macrotextured silicone gel implants discussing our rationale, indications, and results...
November 11, 2016: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/27826488/open-capsulotomy-an-effective-but-overlooked-treatment-for-capsular-contracture-after-breast-augmentation
#18
Eric Swanson
BACKGROUND: The prevailing theory for capsular contracture after breast augmentation is a subclinical capsular infection. A capsulectomy, site change, and implant replacement are recommended. An open capsulotomy leaves the capsule in the patient. Theoretically, such a procedure would be ineffective because it does not remove the infected tissue. Recurrences occurred frequently in women treated in the 1970s when leaky silicone gel implants were in use. Open capsulotomy has not been studied in women implanted with third-generation devices...
October 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27826457/distant-migration-of-multiple-siliconomas-in-lower-extremities-following-breast-implant-rupture-case-report
#19
Joo Hyun Oh, Seung Yong Song, Dae Hyun Lew, Dong Won Lee
Siliconoma from ruptured breast implants has been reported in multiple body sites, including but not limited to the breast parenchyma, axillary lymph nodes, upper arm, and even lower leg. In this regard, we report a rare case of distant silicone migration to the lower extremities after traumatic breast implant rupture. A 55-year-old Asian woman who received bilateral augmentation mammoplasty 20 years ago presented with ruptured breast implants from a car accident 2 years earlier. Magnetic resonance imaging confirmed intracapsular and extracapsular rupture of the right breast implant, showing "linguine sign...
October 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27782705/quantification-of-breast-lesion-compositions-using-low-dose-spectral-mammography-a-feasibility-study
#20
Huanjun Ding, David Sennung, Hyo-Min Cho, Sabee Molloi
PURPOSE: The positive predictive power for malignancy can potentially be improved, if the chemical compositions of suspicious breast lesions can be reliably measured in screening mammography. The purpose of this study is to investigate the feasibility of quantifying breast lesion composition, in terms of water and lipid contents, with spectral mammography. METHODS: Phantom and tissue samples were imaged with a spectral mammography system based on silicon-strip photon-counting detectors...
October 2016: Medical Physics
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