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Cardiac parasympathetic function

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https://www.readbyqxmd.com/read/28321682/recent-advances-and-clinical-applications-of-pet-cardiac-autonomic-nervous-system-imaging
#1
REVIEW
Nabil E Boutagy, Albert J Sinusas
PURPOSE OF REVIEW: The purpose of this review was to summarize current advances in positron emission tomography (PET) cardiac autonomic nervous system (ANS) imaging, with a specific focus on clinical applications of novel and established tracers. RECENT FINDINGS: [(11)C]-Meta-hydroxyephedrine (HED) has provided useful information in evaluation of normal and pathological cardiovascular function. Recently, [(11)C]-HED PET imaging was able to predict lethal arrhythmias, sudden cardiac death (SCD), and all-cause mortality in heart failure patients with reduced ejection fraction (HFrEF)...
April 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28296184/long-term-administration-of-pyridostigmine-attenuates-pressure-overload-induced-cardiac-hypertrophy-by-inhibiting-calcineurin-signalling
#2
Yi Lu, Ming Zhao, Jin-Jun Liu, Xi He, Xiao-Jiang Yu, Long-Zhu Liu, Lei Sun, Li-Na Chen, Wei-Jin Zang
Cardiac hypertrophy is associated with autonomic imbalance, characterized by enhanced sympathetic activity and withdrawal of parasympathetic control. Increased parasympathetic function improves ventricular performance. However, whether pyridostigmine, a reversible acetylcholinesterase inhibitor, can offset cardiac hypertrophy induced by pressure overload remains unclear. Hence, this study aimed to determine whether pyridostigmine can ameliorate pressure overload-induced cardiac hypertrophy and identify the underlying mechanisms...
March 10, 2017: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/28285240/sudarshan-kriya-yoga-improves-cardiac-autonomic-control-in-patients-with-anxiety-depression-disorders
#3
Edgar Toschi-Dias, Eleonora Tobaldini, Monica Solbiati, Giorgio Costantino, Roberto Sanlorenzo, Stefania Doria, Floriana Irtelli, Claudio Mencacci, Nicola Montano
BACKGROUND: Several studies have demonstrated that adjuvant therapies as exercise and breathing training are effective in improving cardiac autonomic control (CAC) in patients with affective spectrum disorders. However, the effects of Sudarshan Kriya Yoga (SKY) on autonomic function in this population is unknown. Our objective was to test the hypothesis that SKY training improves CAC and cardiorespiratory coupling in patients with anxiety and/or depression disorders. METHODS: Forty-six patients with a diagnosis of anxiety and/or depression disorders (DSM-IV) were consecutively enrolled and divided in two groups: 1) conventional therapy (Control) and 2) conventional therapy associated with SKY (Treatment) for 15 days...
March 7, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28279620/asystole-during-direct-laryngoscopy-for-vocal-fold-injection-in-a-healthy-patient
#4
Zahrah Taufique, Gregory R Dion, Milan R Amin
OBJECTIVES: This study aims (1) to present a case of asystole during direct laryngoscopy in an otherwise healthy patient at an outpatient surgery center and (2) to review literature on cardiac complications, specifically asystole and bradycardia, during direct laryngoscopy. METHODS: A 67-year-old woman with no prior cardiac history underwent induction with succinylcholine and remifentanil for direct laryngoscopy and vocal fold augmentation. During suspension laryngoscopy, the patient became asystolic, and advanced care life support measures were started...
March 6, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28270794/antagonistic-and-synergistic-activation-of-cardiovascular-vagal-and-sympathetic-motor-outflows-in-trigeminal-reflexes
#5
REVIEW
Bruno Buchholz, Jazmín Kelly, Eduardo A Bernatene, Nahuel Méndez Diodati, Ricardo J Gelpi
The trigeminal nerve and heart are strongly related through somato-autonomic nervous reflexes that induce rapid changes in cardiovascular function. Several trigeminal reflexes have been described, but the diving and trigeminocardiac reflexes are the most studied. The heart is a target organ dually innervated by the sympathetic and parasympathetic systems. Thus, how cardiac function is regulated during the trigeminal reflexes is the result of the combination of an increased parasympathetic response and increased, decreased, or unaltered sympathetic activity...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28268476/heart-rate-independent-qt-variability-component-can-detect-subclinical-cardiac-autonomic-neuropathy-in-diabetes
#6
Mohammad H Imam, Chandan K Karmakar, Ahsan H Khandoker, Herbert F Jelinek, M Palaniswami
Cardiac autonomic neuropathy (CAN) may lead to life threatening arrhythmia due to denervation of both the parasympathetic and sympathetic branches of autonomic nervous system innervating the heart. CAN is a frequently under diagnosed complication of diabetes, because a patient can have asymptomatic CAN for several years before it is clinically apparent. However, detection of CAN at the early or subclinical stage leads to more effective treatment outcomes. Cardiac autonomic reflex tests (CART) (i.e. Ewing test battery) are normally used for the detection and staging of CAN...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28265216/right-thoracoabdominal-approach-for-retrocardiac-paraganglioma-resection
#7
Carlos A Hinojosa, Hugo Laparra-Escareno, Javier E Anaya-Ayala, Rene Lizola, Adriana Torres-Machorro, Armando Gamboa-Domínguez
Paragangliomas are rare extra-adrenal tumors of sympathetic or parasympathetic paraganglia origin; of these, mediastinal paragangliomas are 2% of all cases. We present the case of a 21-year-old woman with uncontrolled arterial hypertension who had a functioning 6.5 × 6.2-cm retrocardiac paraganglioma firmly attached to the pericardium. The patient underwent tumor resection via a right thoracoabdominal incision; this surgical approach enabled adequate exposure for complete resection without institution of cardiopulmonary bypass or need for cardiac reconstruction or autotransplantation...
February 2017: Texas Heart Institute Journal
https://www.readbyqxmd.com/read/28261792/parasympathetic-reactivity-and-disruptive-behavior-problems-in-young-children-during-interactions-with-their-mothers-and-other-adults-a-preliminary-investigation
#8
Christine E Cooper-Vince, Mariah DeSerisy, Danielle Cornacchio, Amanda Sanchez, Katie A McLaughlin, Jonathan S Comer
Parasympathetic nervous system influences on cardiac functions-commonly indexed via respiratory sinus arrhythmia (RSA)-are central to self-regulation. RSA suppression during challenging emotional and cognitive tasks is often associated with better emotional and behavioral functioning in preschoolers. However, the links between RSA suppression and child behavior across various challenging interpersonal contexts remains unclear. The present study experimentally evaluated the relationship between child RSA reactivity to adult (mother vs...
March 6, 2017: Developmental Psychobiology
https://www.readbyqxmd.com/read/28255249/association-between-obesity-and-heart-rate-variability-indices-an-intuition-toward-cardiac-autonomic-alteration-a-risk-of-cvd
#9
Ram Lochan Yadav, Prakash Kumar Yadav, Laxmi Kumari Yadav, Kopila Agrawal, Santosh Kumar Sah, Md Nazrul Islam
BACKGROUND: Obese people have a higher prevalence of cardiovascular disease, which is supposed to be due to autonomic dysfunction and/or metabolic disorder. The alterations in cardiac autonomic functions bring out the changes in the heart rate variability (HRV) indicators, an assessing tool for cardiac autonomic conditions. OBJECTIVE: To compare the cardiac autonomic activity between obese and normal weight adults and find out the highest association between the indices of HRV and obesity...
2017: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
https://www.readbyqxmd.com/read/28253544/stroke-in-right-dorsal-anterior-insular-cortex-is-related-to-myocardial-injury
#10
Thomas Krause, Kathrin Werner, Jochen B Fiebach, Kersten Villringer, Sophie K Piper, Karl Georg Haeusler, Matthias Endres, Jan F Scheitz, Christian H Nolte
OBJECTIVE: Elevated levels of cardiac troponin and especially their relative changes over time indicate acute myocardial injury. They are also frequently observed after acute ischemic stroke (AIS), indicating poor functional outcome and increased mortality. However, recent evidence showed that in most AIS patients myocardial injury is not caused by coronary ischemia. Instead, stroke lesion location has been suggested to precipitate myocardial injury. METHODS: Voxel-based lesion-symptom mapping (VLSM) was employed in 299 patients who had an MRI-confirmed acute ischemic stroke within the anterior circulation and a high-sensitivity cardiac Troponin T (hs-cTnT) acquired on the day of admission...
March 2, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/28247979/effects-of-exercise-training-intensity-on-cardiac-autonomic-regulation-in-habitual-smokers
#11
Choun-Sub Kim, Maeng-Kyu Kim, Hye-Young Jung, Mi-Ji Kim
BACKGROUND: The sympathoexcitatory effects of cigarette smoking cause an autonomic imbalance that may lead to cardiovascular disease. Aerobic training improves autonomic function by developing cardiorespiratory fitness; however, it is still uncertain whether aerobic training ameliorates the compromised autonomic modulation in smokers. This study aimed to investigate the effects of 8 weeks' aerobic training at different exercise intensities on autonomic regulation in habitual smokers...
March 1, 2017: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/28246702/-interaction-between-heart-and-brain-in-sudden-cardiac-death
#12
M Fatar, I Akin, M Borggrefe, M Platten, A Alonso
The heart and brain are constantly interacting under normal physiological conditions. This interaction is under the control of the autonomic nervous system with parasympathetic and sympathetic nerve fibers including the participating brain structures. Pathological conditions, such as epilepsy and ischemic cerebral stroke influence heart function, especially the frequency and may result in severe arrhythmia. An asymmetric influence of the left and right brain hemispheres on the heart rate is still under debate...
February 28, 2017: Herz
https://www.readbyqxmd.com/read/28228335/alterations-in-cardiac-autonomic-control-in-spinal-cord-injury
#13
Fin Biering-Sørensen, Tor Biering-Sørensen, Nan Liu, Lasse Malmqvist, Jill Maria Wecht, Andrei Krassioukov
A spinal cord injury (SCI) interferes with the autonomic nervous system (ANS). The effect on the cardiovascular system will depend on the extent of damage to the spinal/central component of ANS. The cardiac changes are caused by loss of supraspinal sympathetic control and relatively increased parasympathetic cardiac control. Decreases in sympathetic activity result in heart rate and the arterial blood pressure changes, and may cause arrhythmias, in particular bradycardia, with the risk of cardiac arrest in those with cervical or high thoracic injuries...
February 15, 2017: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/28226649/heart-rate-independent-qt-variability-component-can-detect-subclinical-cardiac-autonomic-neuropathy-in-diabetes
#14
Mohammad H Imam, Chandan K Karmakar, Ahsan H Khandoker, Herbert F Jelinek, M Palaniswami, Mohammad H Imam, Chandan K Karmakar, Ahsan H Khandoker, Herbert F Jelinek, M Palaniswami, Ahsan H Khandoker, Herbert F Jelinek, Chandan K Karmakar, Mohammad H Imam, M Palaniswami
Cardiac autonomic neuropathy (CAN) may lead to life threatening arrhythmia due to denervation of both the parasympathetic and sympathetic branches of autonomic nervous system innervating the heart. CAN is a frequently under diagnosed complication of diabetes, because a patient can have asymptomatic CAN for several years before it is clinically apparent. However, detection of CAN at the early or subclinical stage leads to more effective treatment outcomes. Cardiac autonomic reflex tests (CART) (i.e. Ewing test battery) are normally used for the detection and staging of CAN...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28208852/alteration-of-heart-rate-variability-in-patients-of-depression
#15
Deepti Jangpangi, Sunita Mondal, Rajiv Bandhu, Dinesh Kataria, Asha Gandhi
INTRODUCTION: Altered cardiac autonomic functions in form of reduced Heart Rate Variability (HRV) have been found to be associated with increased cardiovascular morbidity and mortality in depressive patients. AIM: To investigate the relationship between HRV measures, which is a non-invasive marker of autonomic nervous system and depression. MATERIALS AND METHODS: The study included a convenient sample size of drug naive depressive patients (n=30) diagnosed on basis of ICD-10 and compared with age and gender matched healthy volunteers (n=30)...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28169914/cardiac-autonomic-function-and-hot-flashes-among-perimenopausal-and-postmenopausal-women
#16
Carolyn J Gibson, Wendy Berry Mendes, Michael Schembri, Deborah Grady, Alison J Huang
OBJECTIVE: Abnormalities in autonomic function are posited to play a pathophysiologic role in menopausal hot flashes. We examined relationships between resting cardiac autonomic activity and hot flashes in perimenopausal and postmenopausal women. METHODS: Autonomic function was assessed at baseline and 12 weeks among perimenopausal and postmenopausal women (n = 121, mean age 53 years) in a randomized trial of slow-paced respiration for hot flashes. Pre-ejection period (PEP), a marker of sympathetic activation, was measured with impedance cardiography...
February 6, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28167918/quantifying-effects-of-pharmacological-blockers-of-cardiac-autonomous-control-using-variability-parameters
#17
Renata Miyabara, Karsten Berg, Jan F Kraemer, Ovidiu C Baltatu, Niels Wessel, Luciana A Campos
Objective: The aim of this study was to identify the most sensitive heart rate and blood pressure variability (HRV and BPV) parameters from a given set of well-known methods for the quantification of cardiovascular autonomic function after several autonomic blockades. Methods: Cardiovascular sympathetic and parasympathetic functions were studied in freely moving rats following peripheral muscarinic (methylatropine), β1-adrenergic (metoprolol), muscarinic + β1-adrenergic, α1-adrenergic (prazosin), and ganglionic (hexamethonium) blockades...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28154104/heart-brain-axis-effects-of-neurologic-injury-on-cardiovascular-function
#18
Pouya Tahsili-Fahadan, Romergryko G Geocadin
A complex interaction exists between the nervous and cardiovascular systems. A large network of cortical and subcortical brain regions control cardiovascular function via the sympathetic and parasympathetic outflow. A dysfunction in one system may lead to changes in the function of the other. The effects of cardiovascular disease on the nervous system have been widely studied; however, our understanding of the effects of neurological disorders on the cardiovascular system has only expanded in the past 2 decades...
February 3, 2017: Circulation Research
https://www.readbyqxmd.com/read/28152451/can-natural-ways-to-stimulate-the-vagus-nerve-improve-seizure-control
#19
REVIEW
Alan W C Yuen, Josemir W Sander
The vagus nerve (VN) is the longest cranial nerve, innervating the neck, thorax and abdomen, with afferent fibers transmitting a range of interoceptive stimuli and efferent fibres to somatic structures and autonomic preganglions. Over the last few decades, electrical stimulation of the VN using implanted devices (VNS) has been developed leading to its approval for the treatment of epilepsy and depression. More recently, non-invasive devices to stimulation the VN have been developed. The VN has many functions and the activity that is most amenable to assessment is its effect in controlling the cardiac rhythm...
February 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28151944/diurnal-variation-and-twenty-four-hour-sleep-deprivation-do-not-alter-supine-heart-rate-variability-in-healthy-male-young-adults
#20
Daniel S Quintana, Torbjørn Elvsåshagen, Nathalia Zak, Linn B Norbom, Per Ø Pedersen, Sophia H Quraishi, Atle Bjørnerud, Ulrik F Malt, Inge R Groote, Tobias Kaufmann, Ole A Andreassen, Lars T Westlye
Heart rate variability (HRV) has become an increasingly popular index of cardiac autonomic control in the biobehavioral sciences due to its relationship with mental illness and cognitive traits. However, the intraindividual stability of HRV in response to sleep and diurnal disturbances, which are commonly reported in mental illness, and its relationship with executive function are not well understood. Here, in 40 healthy adult males we calculated high frequency HRV-an index of parasympathetic nervous system (PNS) activity-using pulse oximetry during brain imaging, and assessed attentional and executive function performance in a subsequent behavioral test session at three time points: morning, evening, and the following morning...
2017: PloS One
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