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https://www.readbyqxmd.com/read/28046601/su-f-t-232-monthly-quality-assurance-in-external-beam-radiation-therapy-using-a-single-system
#1
K Ding, T Ji, I Iordachita, E Velarde, J Hyatt, J Wong
PURPOSE: Monthly quality assurance (QA) is time consuming for external beam radiation therapy, taking as long as 6-8 hours for each machine. It is due to the use and setup of multiple devices for different QA procedures. We have developed a single system with rotational capability for the measurement of both optical light and radiation which significantly reduces the time spent on Monthly QA. METHODS: A single system using mirrors, a phosphor screen and a CCD camera is housed on a cylindrical motor so that it can rotate 360 degrees...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28025558/empirical-analysis-and-modeling-of-stop-line-crossing-time-and-speed-at-signalized-intersections
#2
Keshuang Tang, Fen Wang, Jiarong Yao, Jian Sun
In China, a flashing green (FG) indication of 3 s followed by a yellow (Y) indication of 3 s is commonly applied to end the green phase at signalized intersections. Stop-line crossing behavior of drivers during such a phase transition period significantly influences safety performance of signalized intersections. The objective of this study is thus to empirically analyze and model drivers' stop-line crossing time and speed in response to the specific phase transition period of FG and Y. High-resolution trajectories for 1465 vehicles were collected at three rural high-speed intersections with a speed limit of 80 km/h and two urban intersections with a speed limit of 50 km/h in Shanghai...
December 23, 2016: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28007336/the-combined-frequency-of-igf-and-myostatin-polymorphism-among-track-field-athletes-and-swimmers
#3
Sigal Ben-Zaken, Yoav Meckel, Dan Nemet, Alon Eliakim
OBJECTIVE: The IGF C-1245T (rs35767) and the myostatin (MSTN) Lys(K)-153Arg(R) genetic polymorphism may influence skeletal muscle phenotypes and athletic performance. Carrying the minor IGF T allele and the myostatin rare R allele was associated with higher circulating IGF-I levels, greater muscle mass and improved performance. The aim of the present study was to assess the combined frequency of the IGF 1245T (rs35767) and MSTN 153Arg(R) polymorphism among Israeli track and field athletes (n=111) and swimmers (n=80)...
December 15, 2016: Growth Hormone & IGF Research
https://www.readbyqxmd.com/read/27918655/activity-profiles-and-positional-differences-of-handball-players-during-the-world-championships-in-qatar-2015
#4
Marco Cardinale, Rodney Whiteley, Ahmed Abdelrahman Hosny, Nebojsa Popovic
PURPOSE: Handball is an Olympic sport played indoor by 6 court players and one goalkeeper with rolling substitutions. Limited data exist on elite players competing in a World Championship and virtually no information exits on the evolution of time-motion performance over the course of a long tournament. Therefore, the aim of this study was to analyze time motion characteristics of elite male handball players of the last World Championships played in Qatar in 2015. METHODS: 384 Players from 24 national teams were analyzed during 88 matches using a tracking camera system and a bespoke software (Prozone Handball V...
December 5, 2016: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/27917706/the-changes-of-positive-selection-within-env-gene-of-hiv-1-b-crf07_bc-and-crf08_bc-from-china-over-time
#5
Tingting Li, Binlian Sun, Yanyan Jiang, Haiyan Zeng, Yanpeng Li, Yan Wang, Rongge Yang
: It is not clear about the possible evolutionary changes of the three predominant strains of HIV-1 in China over the course of the epidemic. Envelope (env) gene of HIV-1 is a good target for this evolutionary pressure for its enriched epitopes. METHODS: We collected 159 full or part of env sequences sampled between 1997 and 2010 from database of China, we calculated the genetic distance, detected the positively selected sites by PAML suite and then compared the number using Fisher's exact test between the early period 1997 to 2003and the late period2004 to 2010...
December 5, 2016: Current HIV Research
https://www.readbyqxmd.com/read/27909228/divergent-outcomes-of-fructose-consumption-on-exercise-capacity-of-rats-friend-or-foe
#6
Angela Sun, An Huang, Elizabeth Kertowidjojo, Su Song, Thomas H Hintze, Dong Sun
To test the hypothesis that high fructose (HF) consumption divergently affects exercise capability, as a function of feeding duration, rats were fed a normal (as control) or a normal caloric diet with HF for 3, 6, 10 and 30 days respectively, and run on a treadmill. Results show that running distance and work were significantly increased, associated with greater exercise oxygen consumption in rats fed HF for 3 (HF-3D) and 6 days, but were decreased in rats fed HF for 30 days (HF-30D) compared to their respective control rats...
December 1, 2016: Journal of Applied Physiology
https://www.readbyqxmd.com/read/27905293/long-term-exercise-in-mice-has-sex-dependent-benefits-on-body-composition-and-metabolism-during-aging
#7
Rachel C McMullan, Scott A Kelly, Kunjie Hua, Brian K Buckley, James E Faber, Fernando Pardo-Manuel de Villena, Daniel Pomp
Aging is associated with declining exercise and unhealthy changes in body composition. Exercise ameliorates certain adverse age-related physiological changes and protects against many chronic diseases. Despite these benefits, willingness to exercise and physiological responses to exercise vary widely, and long-term exercise and its benefits are difficult and costly to measure in humans. Furthermore, physiological effects of aging in humans are confounded with changes in lifestyle and environment. We used C57BL/6J mice to examine long-term patterns of exercise during aging and its physiological effects in a well-controlled environment...
November 2016: Physiological Reports
https://www.readbyqxmd.com/read/27863044/exercise-for-healthy-flow
#8
EDITORIAL
P Hillmeister, E Buschmann, P B Persson, A Bondke Persson
No abstract text is available yet for this article.
January 2017: Acta Physiologica
https://www.readbyqxmd.com/read/27855981/the-thigh-and-leg-of-homo-naledi
#9
Damiano Marchi, Christopher S Walker, Pianpian Wei, Trenton W Holliday, Steven E Churchill, Lee R Berger, Jeremy M DeSilva
This paper describes the 108 femoral, patellar, tibial, and fibular elements of a new species of Homo (Homo naledi) discovered in the Dinaledi chamber of the Rising Star cave system in South Africa. Homo naledi possesses a mosaic of primitive, derived, and unique traits functionally indicative of a bipedal hominin adapted for long distance walking and possibly running. Traits shared with australopiths include an anteroposteriorly compressed femoral neck, a mediolaterally compressed tibia, and a relatively circular fibular neck...
November 15, 2016: Journal of Human Evolution
https://www.readbyqxmd.com/read/27822290/dietary-selenium-augments-sarcoplasmic-calcium-release-and-mechanical-performance-in-mice
#10
Dóra Bodnár, Olga Ruzsnavszky, Tamás Oláh, Beatrix Dienes, Ildikó Balatoni, Éva Ungvári, Ilona Benkő, Beáta Babka, József Prokisch, László Csernoch, Péter Szentesi
BACKGROUND: As an essential trace element selenium plays a significant role in many physiological functions of the organs. It is found within muscles as selenocystein in selenoprotein N, which is involved in redox-modulated calcium homeostasis and in protection against oxidative stress. METHODS: The effects of two different selenium compounds (selenate and NanoSe in 0.5 and 5 ppm concentration for two weeks) on muscle properties of mice were examined by measuring in vivo muscle performance, in vitro force in soleus (SOL) and extensor digitorum longus (EDL) muscles and changes in intracellular Ca(2+) concentration in single fibers from flexor digitorum brevis (FDB) muscle...
2016: Nutrition & Metabolism
https://www.readbyqxmd.com/read/27815238/strategies-and-factors-associated-with-preparing-for-competing-in-the-heat-a-cohort-study-at-the-2015-iaaf-world-athletics-championships
#11
Julien D Périard, Sébastien Racinais, Toomas Timpka, Örjan Dahlström, Armin Spreco, Jenny Jacobsson, Victor Bargoria, Karin Halje, Juan-Manuel Alonso
PURPOSE: Assess exertional heat illness (EHI) history and preparedness in athletes competing in a World Athletics Championships under hot/humid conditions and identify the factors associated with preparedness strategies. METHODS: Of the 207 registered national teams invited to participate in the study, 50 (24%) accepted. The 957 athletes (49% of all 1965 registered) in these teams were invited to complete a precompetition questionnaire evaluating EHI history, heat stress prevention (heat acclimatisation, precooling and hydration) and recovery...
November 4, 2016: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/27812406/pacing-during-an-ultramarathon-running-event-in-hilly-terrain
#12
Hugo A Kerhervé, Tom Cole-Hunter, Aaron N Wiegand, Colin Solomon
PURPOSE: The dynamics of speed selection as a function of distance, or pacing, are used in recreational, competitive, and scientific research situations as an indirect measure of the psycho-physiological status of an individual. The purpose of this study was to determine pacing on level, uphill and downhill sections of participants in a long (>80 km) ultramarathon performed on trails in hilly terrain. METHODS: Fifteen ultramarathon runners competed in a  173 km event (five finished at  103 km) carrying a Global-Positioning System (GPS) device...
2016: PeerJ
https://www.readbyqxmd.com/read/27812098/interrogating-emergent-transport-properties-for-molecular-motor-ensembles-a-semi-analytical-approach
#13
Shreyas Bhaban, Donatello Materassi, Mingang Li, Thomas Hays, Murti Salapaka
Intracellular transport is an essential function in eucaryotic cells, facilitated by motor proteins-proteins converting chemical energy into kinetic energy. It is understood that motor proteins work in teams enabling unidirectional and bidirectional transport of intracellular cargo over long distances. Disruptions of the underlying transport mechanisms, often caused by mutations that alter single motor characteristics, are known to cause neurodegenerative diseases. For example, phosphorylation of kinesin motor domain at the serine residue is implicated in Huntington's disease, with a recent study of phosphorylated and phosphomimetic serine residues indicating lowered single motor stalling forces...
November 2016: PLoS Computational Biology
https://www.readbyqxmd.com/read/27807171/effects-of-long-term-exercise-on-age-related-hearing-loss-in-mice
#14
Chul Han, Dalian Ding, Maria-Cecilia Lopez, Senthilvelan Manohar, Yanping Zhang, Mi-Jung Kim, Hyo-Jin Park, Karessa White, Yong Hwan Kim, Paul Linser, Masaru Tanokura, Christiaan Leeuwenburgh, Henry V Baker, Richard J Salvi, Shinichi Someya
: Regular physical exercise reduces the risk for obesity, cardiovascular diseases, and disability and is associated with longer lifespan expectancy (Taylor et al., 2004; Pahor et al., 2014; Anton et al., 2015; Arem et al., 2015). In contrast, decreased physical function is associated with hearing loss among older adults (Li et al., 2013; Chen et al., 2015). Here, we investigated the effects of long-term voluntary wheel running (WR) on age-related hearing loss (AHL) in CBA/CaJ mice, a well established model of AHL (Zheng et al...
November 2, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27805723/from-lead-to-drug-utilizing-a-mannich-reaction-the-topotecan-story
#15
REVIEW
Franz Bracher, Tim Tremmel
Natural products are a rich source of bioactive compounds, and numerous natural compounds have found application in cancer chemotherapy. However, unfavorable physicochemical properties often prevent the use of the original natural product as a drug. A prominent example is camptothecin from the Chinese tree Camptotheca acuminata, which shows extraordinary cytotoxic activity based on a specific molecular mode of action (inhibition of human topoisomerase I). Due to its extremely poor solubility, the original natural product cannot be used as a drug...
November 2, 2016: Archiv der Pharmazie
https://www.readbyqxmd.com/read/27792164/the-effect-of-a-20-km-run-on-appetite-regulation-in-long-distance-runners
#16
Chihiro Kojima, Aya Ishibashi, Kumiko Ebi, Kazushige Goto
The purpose of the present study was to investigate appetite-related hormonal responses and energy intake after a 20 km run in trained long distance runners. Twenty-three male long-distance runners completed two trials: either an exercise trial consisting of a 20 km outdoor run (EX) or a control trial with an identical period of rest (CON). Blood samples were collected to determine plasma acylated ghrelin, peptide YY3-36 (PYY3-36) and other hormonal and metabolite concentrations. Energy intake during a buffet test meal was also measured 30 min after the exercise or rest periods...
October 26, 2016: Nutrients
https://www.readbyqxmd.com/read/27785775/risk-and-protective-factors-for-middle-and-long-distance-running-related-injury
#17
REVIEW
Adam Hulme, Rasmus Oestergaard Nielsen, Toomas Timpka, Evert Verhagen, Caroline Finch
BACKGROUND: Despite a rapidly growing body of research, a systematic evidence compilation of the risk and protective factors for middle- and long-distance running-related injury (RRI) was lacking. OBJECTIVES: Our objective was to compile the evidence about modifiable and non-modifiable training-related and behavioral risk and protective factors for middle- and long-distance RRI. METHODS: We searched five databases (PubMed, CINAHL, MEDLINE, SPORTDiscus, and PsycINFO) for the dates 1 January 1970 to 31 December 2015, inclusive, for original peer-reviewed articles...
October 27, 2016: Sports Medicine
https://www.readbyqxmd.com/read/27766135/sex-differences-in-time-perception-during-self-paced-running
#18
Nicholas J Hanson, Janet Buckworth
Time perception during exercise may be affected by chosen intensity, and may also affect enjoyment of exercise and subsequent long-term adherence. However, little is known about how individuals perceive the passage of time during exercise, or if factors such as sex are influential. The purpose of this study was to determine if there are sex related differences in perception of time during a bout of exercise in experienced runners. Twenty-two recreational runners (11 men, 11 women) participated in a bout of treadmill running where they were allowed to select their intensity...
2016: International Journal of Exercise Science
https://www.readbyqxmd.com/read/27757284/the-relationship-between-trunk-endurance-plank-tests-and-athletic-performance-tests-in-adolescent-soccer-players
#19
Atsushi Imai, Koji Kaneoka
BACKGROUND: Although it is believed that trunk function is important for athletic performance, few researchers have demonstrated a significant relationship between the trunk function and athletic performance. Recently, the prone plank and side plank tests have been used to assess trunk function. PURPOSE: The purpose of this study was to investigate the relationships between trunk endurance plank tests and athletic performance tests, including whether there is a relationship between long distance running and trunk endurance plank tests in adolescent male soccer players...
October 2016: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/27755733/spatial-processes-structuring-riparian-plant-communities-in-agroecosystems-implications-for-restoration
#20
Bérenger Bourgeois, Eduardo González, Anne Vanasse, Isabelle Aubin, Monique Poulin
The disruption of hydrological connectivity by human activities such as flood regulation or land-use changes strongly impacts riparian plant communities. However, landscape-scale processes have generally been neglected in riparian restoration projects as opposed to local conditions, even though such processes might largely influence community recovery. We surveyed plant composition of field edges and riverbanks in 51 riparian zones restored by tree planting (565 1-m(2) plots) within two agricultural watersheds in southeastern Québec, Canada...
October 2016: Ecological Applications: a Publication of the Ecological Society of America
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