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Hypertrophic pyloric stenosis

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https://www.readbyqxmd.com/read/28901937/advances-in-paediatric-gastroenterology
#1
REVIEW
Paul K H Tam, Patrick H Y Chung, Shawn D St Peter, Christopher P Gayer, Henri R Ford, Greta C H Tam, Kenneth K Y Wong, Mikko P Pakarinen, Mark Davenport
Recent developments in paediatric gastrointestinal surgery have focused on minimally invasive surgery, the accumulation of high-quality clinical evidence, and scientific research. The benefits of minimally invasive surgery for common disorders like appendicitis and hypertrophic pyloric stenosis are all supported by good clinical evidence. Although minimally invasive surgery has been extended to neonatal surgery, it is difficult to establish its role for neonatal disorders such as oesophageal atresia and biliary atresia through clinical trials because of the rarity of these disorders...
September 9, 2017: Lancet
https://www.readbyqxmd.com/read/28842652/application-of-color-doppler-ultrasound-combined-with-doppler-imaging-artifacts-in-the-diagnosis-and-estimate-of-congenital-hypertrophic-pyloric-stenosis
#2
Suihong Ma, Jianhua Liu, Youxiang Zhang, Yuwen Yang, Hai Jin, Xiaomei Ma, Hongqin Wei
Congenital Hypertrophic Pyloric Stenosis (CHPS) is a disease condition that is caused as a result of pylorus wall hypertrophy and hyperplasia. In this study, we used color Doppler flow imaging (CDFI) and Doppler artifacts technique to observe the blood flow of hypertrophic pylorus tissue and the dynamic imaging of liquid passing through the pyloric canal in CHPS infants. 65 cases of CHPS infants and 50 infants without CHPS served as control group. We found that there were statistically significant differences between the blood flow grade of muscular layer and mucosal layer between CHPS and control infants, but no significant differences were observed in the same group...
August 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28770145/a-difficult-recurrent-hypertrophic-pyloric-stenosis
#3
Hamdi Louati, Hayet Zitouni, Manel Belhajmansour, Mahdi Ben Dhaou, Mohamed Jalouli, Riadh Mhiri, Rim Kallel, Tahya Boudawara
No abstract text is available yet for this article.
April 2017: Journal of Neonatal Surgery
https://www.readbyqxmd.com/read/28701060/epidemiological-and-clinical-characteristics-of-304-patients-with-infantile-hypertrophic-pyloric-stenosis-in-anhui%C3%A2-province-of-east-china-2012-2015
#4
Jing Li, Wei Gao, Ji-Min Zhu, Wei Zuo, Xiang Liu
OBJECTIVE: To analyze the clinical and epidemiological features of patients with infantile hypertrophic pyloric stenosis (IHPS) so as to provide scientific evidences for diagnosis and prevention of IHPS. METHODS: We performed a retrospective study of IHPS patients diagnosed from 2012 to 2015 at Anhui Provincial Children's Hospital. Demographic characteristic and clinical data were collected. RESULTS: Three hundred four patients (264 males and 40 females) were studied...
July 12, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28701002/atropine-treatment-for-hypertrophic-pyloric-stenosis-a-systematic-review-and-meta-analysis
#5
Giuseppe Lauriti, Valentina Cascini, Pierluigi Lelli Chiesa, Agostino Pierro, Augusto Zani
No abstract text is available yet for this article.
July 12, 2017: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28648281/50-years-ago-in-the-journal-of-pediatrics-the-radiographic-diagnosis-of-congenital-hypertrophic-pyloric-stenosis
#6
Carlos A Cuello-Garcia
No abstract text is available yet for this article.
July 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28576429/population-level-surgical-outcomes-for-infantile-hypertrophic-pyloric-stenosis
#7
Nick Lansdale, Nadeem Al-Khafaji, Patrick Green, Simon E Kenny
OBJECTIVES: Determine national outcomes for pyloromyotomy; how these are affected by: (i) surgical approach (open/laparoscopic), or (ii) centre type/volume and establish potential benchmarks of quality. METHODS: Hospital Episode Statistics data were analysed for admissions 2002-2011. Data presented as median (IQR). RESULTS: 9686 infants underwent pyloromyotomy (83% male). Surgery was performed in 22 specialist (SpCen) and 39 nonspecialist centres (NonSpCen)...
May 21, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28550912/does-metabolic-alkalosis-influence-cerebral-oxygenation-in-infantile-hypertrophic-pyloric-stenosis
#8
Matthias Nissen, Grigore Cernaianu, Rene Thränhardt, Mohammad R Vahdad, Karin Barenberg, Ralf-Bodo Tröbs
BACKGROUND: This pilot study focuses on regional tissue oxygenation (rSO2) in patients with infantile hypertrophic pyloric stenosis in a perioperative setting. To investigate the influence of enhanced metabolic alkalosis (MA) on cerebral (c-rSO2) and renal (r-rSO2) tissue oxygenation, two-site near-infrared spectroscopy (NIRS) technology was applied. MATERIALS AND METHODS: Perioperative c-rSO2, r-rSO2, capillary blood gases, and electrolytes from 12 infants were retrospectively compared before and after correction of MA at admission (T1), before surgery (T2), and after surgery (T3)...
May 15, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28508920/chronic-low-dose-prostaglandin-and-neonatal-heart-block
#9
Safwat A Aly, Sawsan M Awad, Ra-Id Abdulla, Suhaib Kazmouz, Hoang H Nguyen
Long-term prostaglandin use is commonly associated with side effects such as cortical proliferation of the bones, hypertrophic pyloric stenosis, and soft tissue swelling of the extremities. We report a neonate with critical coarctation of the aorta, who developed second and third degree atrioventricular blocks associated with prolonged prostaglandin E1 (PGE1) infusion. Interestingly, these conduction blocks only occurred at low PGE1 dose. The rhythm disturbances resolved promptly with the discontinuation of PGE1 following surgical repair...
May 16, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28318599/perinatal-risk-factors-for-infantile-hypertrophic-pyloric-stenosis-a-meta-analysis
#10
REVIEW
Jianghu Zhu, Tingting Zhu, Zhenlang Lin, Yi Qu, Dezhi Mu
BACKGROUND: Infantile hypertrophic pyloric stenosis (IHPS) is the most common surgical cause of nonbilious vomiting in infancy. The etiology of IHPS is not completely understood. Hence, we performed a meta-analysis to investigate the association between perinatal factors and IHPS onset. METHODS: The MEDLINE, EMBASE, PubMed and Cochrane Library databases were searched for studies published in English before December 2016. The combined odd ratios (ORs) and 95% confidence intervals (CIs) were calculated using random-effects models...
March 15, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28295432/excessive-bright-echoes-sign-for-hypertrophic-pyloric-stenosis-suggest-the-diagnosis-gastric-pneumatosis-and-portal-venous-gas-in-infants-suggest-hps
#11
Harris L Cohen, P Blake Chism, Ina Radtke
We describe a new finding, the "excessive bright echoes" sign, for the diagnosis of hypertrophic pyloric stenosis (HPS). Portal venous gas and gastric wall pneumatosis were noted in 4 vomiting infants proven to have HPS. Portal venous gas can be concerning for ischemic bowel. Gastric wall pneumatosis can be seen in association with necrotizing enterocolitis and has been associated with increased gastric pressure from severe, usually proximal, bowel obstruction. Our HPS cases had prominent bright punctate echoes on sonography of the liver, portal vein lumen, and gastric wall...
May 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28238307/comparing-pyloromyotomy-outcomes-across-canada
#12
Alexander C Ednie, Ofer Amram, Nadine Schuurman, Natalie L Yanchar
BACKGROUND: Changing patterns of referral and management of hypertrophic pyloric stenosis (HPS) in North America have recently been described. Comfort with perioperative management, anesthesia, and corrective surgery have been cited as reasons for these changes. Our primary objective was to assess pyloromyotomy outcomes between different hospital types across Canada. The secondary objective was to geospatially map all pyloromyotomies to identify regions of higher HPS incidence across Canada...
May 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28038764/is-all-cause-readmission-an-appropriate-performance-measure-for-pediatric-surgeons-a-case-study-in-pyloromyotomy
#13
Isobel H Marks, David C Chang, Peter T Masiakos, Cassandra M Kelleher
INTRODUCTION: All cause readmissions are used as a surrogate metric for quality of care for both hospitals and physicians, and are considered in pay for performance initiatives. However, the integrity of using all cause readmissions as a benchmark for surgical outcomes has received little attention. Pyloromyotomy for hypertrophic pyloric stenosis is considered a safe pediatric surgical procedure with few complications or readmissions. The incidence of in hospital complications has been reported, however the rate of readmissions and specifically the proportion of readmissions related to surgical complications have not been previously reported...
September 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27942806/laparoscopic-versus-open-pyloromyotomy-in-infants-a-systematic-review-and-meta-analysis
#14
REVIEW
Chethan Sathya, Carolyn Wayne, Anna Gotsch, Jennifer Vincent, Katrina J Sullivan, Ahmed Nasr
PURPOSE: To determine whether open or laparoscopic pyloromyotomy is superior for the treatment of hypertrophic pyloric stenosis in infants. METHODS: We searched MEDLINE, EMBASE, and CENTRAL for articles comparing laparoscopic and open procedures. We conducted meta-analyses when possible and described other results narratively. RESULTS: Our meta-analyses revealed no significant difference in our primary outcome of major complications [risk difference (RD) 0...
March 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/27915443/successful-combination-of-endoscopic-pyloromyotomy-and-balloon-dilatation-for-hypertrophic-pyloric-stenosis-in-an-older-child-a-novel-procedure
#15
Satoshi Yokoyama, Shiro Uyama, Hiroyoshi Iwagami, Yukitaka Yamashita
BACKGROUND: Hypertrophic pyloric stenosis (HPS) is a rare cause of gastric outlet obstruction beyond infancy. Ramstedt pyloromyotomy remains the gold standard treatment for HPS. This type of HPS can be managed successfully with pyloromyotomy under laparoscopic or open procedures. Endoscopic pyloric balloon dilation (EPBD) has not been recommended in the treatment of HPS, and there are only a small number of reported cases who had had successful endoscopic pyloromyotomy (EP) for HPS only in infants...
December 2016: Surgical Case Reports
https://www.readbyqxmd.com/read/27855150/a-novel-missense-mutation-in-the-transcription-factor-foxf1-cosegregating-with-infantile-hypertrophic-pyloric-stenosis-in-the-extended-pedigree-linked-to-ihps5-on-chromosome-16q24
#16
Kate V Everett, Paris Ataliotis, Barry A Chioza, Charles Shaw-Smith, Eddie M K Chung
BACKGROUND: The aim was to identify susceptibility alleles for infantile hypertrophic pyloric stenosis (IHPS) in a pedigree previously linked to IHPS5 on chromosome 16q24. METHODS: We screened the positional and functional candidate gene FOXF1 by Sanger sequencing in a single affected individual. All family members for whom DNA was available were genotyped to determine cosegregation status of the putative causal variant. Immunofluorescence studies were performed to compare the cellular localization of wildtype and mutant form of the protein...
April 2017: Pediatric Research
https://www.readbyqxmd.com/read/27829521/a-randomized-trial-to-assess-advancement-of-enteral-feedings-following-surgery-for-hypertrophic-pyloric-stenosis
#17
RANDOMIZED CONTROLLED TRIAL
Troy A Markel, Melissa R Scott, Samantha M Stokes, Alan P Ladd
PURPOSE: The rate of feeding advancement following surgery for hypertrophic pyloric stenosis (HPS) affects length of stay. We hypothesized that: 1) a relaxed feeding regimen following pyloromyotomy would allow infants to achieve feeding goals more quickly without affecting postoperative emesis, and 2) preoperative metabolic derangements would impair the ability to advance feedings following pyloromyotomy. METHODS: A prospective, randomized trial compared two postoperative feeding methods...
April 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27803770/update-on-endoscopic-management-of-gastric-outlet-obstruction-in-children
#18
REVIEW
Hsun-Chin Chao
Endoscopic balloon dilatation (EBD) and surgical intervention are two most common and effective treatments for gastric outlet obstruction. Correction of gastric outlet obstruction without the need for surgery is an issue that has been tried to be resolved in these decades; this management has developed with EBD, advanced treatments like local steroid injection, electrocauterization, and stent have been added recently. The most common causes of pediatric gastric outlet obstruction are idiopathic hypertrophic pyloric stenosis, peptic ulcer disease followed by the ingestion of caustic substances, stenosis secondary to surgical anastomosis; antral web, duplication cyst, ectopic pancreas, and other rare conditions...
October 16, 2016: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27775311/-infantile-hypertrofic-pyloric-stenosis-or-gastric-adenomyoma-differential-diagnosis-of-gastric-outlet-obstruction-in-children
#19
M Oviedo Gutiérrez, S Amat Valero, A Gómez Farpón, C Montalvo Ávalos, L Fernández García, D C Lara Cárdenas, S Barnes Marañón, C Granell Suárez, N Vega Mata, A J López López, M González Guerrero, V Álvarez Muñoz
PURPOSE: Gastrointestinal adenomyoma is a rare benign tumor most frequently located in the stomach. The differential diagnosis is wide because of its large clinical spectrum and unspecific radiological findings. Surgical excision is both diagnostic and therapeutic. CASE REPORT: A 49-days old girl presented with nonbilious vomiting of 48 hours of evolution. Infantile hypertrofic pyloric stenosis was suspected. Ultrasound showed a nonobstructive nodular lesion in the anterior pyloric wall...
July 20, 2015: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/27757585/vomiting-in-an-infant-with-congenital-nephrotic-syndrome-questions
#20
Toshiyuki Takahashi, Yasuyuki Sato, Takeshi Yamazaki, Asako Hayashi, Takayuki Okamoto
BACKGROUND: Most patients with congenital nephrotic syndrome (CNS) exhibit a failure to thrive. A previous study reported that five of 41 (12 %) infants with CNS had hypertrophic pyloric stenosis (HPS) requiring surgery. The reason for this is undetermined, and there are few reports regarding the relationship between these conditions or their clinical course. CASE DIAGNOSIS/TREATMENT: We present the case of a 4-month-old girl with CNS. She did not show typical manifestations of HPS, but thickened mucosal and submucosal layers and hypertrophy of the pyloric muscle were detected by repeated ultrasound examinations prior to the diagnosis of HPS...
October 18, 2016: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
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