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Acute edema pulmonary

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https://www.readbyqxmd.com/read/29784497/cystic-fibrosis-and-lower-extremity-edema-a-case-of-intraoperative-diagnosis-of-acute-deep-venous-thrombosis-and-pulmonary-embolism-in-a-double-lung-transplant-recipient-using-point-of-care-ultrasound
#1
Vladyslav Melnyk, Dennis Phillips, Travis Schisler, Kathirvel Subramaniam
No abstract text is available yet for this article.
April 21, 2018: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29783158/pirfenidone-ameliorates-lipopolysaccharide-induced-pulmonary-inflammation-and-fibrosis-by-blocking-nlrp3-inflammasome-activation
#2
Yi Li, Haitao Li, Shuai Liu, Pinhua Pan, Xiaoli Su, Hongyi Tan, Dongdong Wu, Lemeng Zhang, Chao Song, Minhui Dai, Qian Li, Zhi Mao, Yuan Long, Yongbin Hu, Chengping Hu
Acute respiratory distress syndrome(ARDS)is a severe clinical disorder characterized by its acute onset, diffuse alveolar damage, intractable hypoxemia, and non-cardiogenic pulmonary edema. Acute lung injury(ALI) can trigger persistent lung inflammation and fibrosis through activation of the NLRP3 inflammasome and subsequent secretion of mature IL-1β, suggesting that the NLRP3 inflammasome is a potential therapeutic target for ALI, for which new therapeutic approaches are needed. Our present study aims to assess whether pirfenidone,with anti-fibrotic and anti-inflammatory properties, can improve LPS-induced inflammation and fibrosis by inhibiting NLRP3 inflammasome activation...
May 18, 2018: Molecular Immunology
https://www.readbyqxmd.com/read/29782290/-the-notion-of-chf-course-stability-is-it-acceptable-for-russian-practice
#3
I V Fomin, N Kraiem, D S Polyakov, N G Vinogradova, F Y Valikulova, A R Vaysberg, E V Shechrbinina
AIM: To evaluate preparedness of physicians in real clinical practice to strive for stabilizing the course of CHF by control of clinical and hemodynamic indexes both in prevention of admission for decompensated CHF and following discharge from the hospital. MATERIALS AND METHODS: The study included 750 CHF patients with any NYHA FC who were admitted in emergency for decompensated CHF. All patients with CHF were followed up for a year after discharge from the hospital...
2018: Kardiologiia
https://www.readbyqxmd.com/read/29776826/recognition-of-sympathetic-crashing-acute-pulmonary-edema-scape-and-use-of-high-dose-nitroglycerin-infusion
#4
Samantha Paone, Leigha Clarkson, Billy Sin, Sheena Punnapuzha
Sympathetic Crashing Acute Pulmonary Edema (SCAPE), or flash pulmonary edema, is the extreme end of the acute pulmonary edema spectrum. A sympathetic surge occurs as a result of decreased systemic perfusion resulting in further increases in afterload, causing the patient to decompensate. Patients can decompensate quickly, therefore patients require rapid interventions. The use of high-dose nitroglycerin (HDN) has been a topic of interest as it is believed to achieve preload and afterload reduction. However, its use continues to be controversial due to concerns of drug induced hypotension, syncope or paresthesia...
May 10, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29775917/difficulties-in-interpretation-when-assessing-prolonged-and-subacute-exposure-to-the-toxic-effects-of-chlorine
#5
Marek Wiergowski, Ireneusz Sołtyszewski, Jacek Sein Anand, Michał Kaliszan, Jolanta Anita Wilmanowska, Zbigniew Jankowski, Marcin Łukasik
The purpose of this study was a toxicological interpretation of exposure to chlorine with unusual course. Medical, clinical and court records, as well as reviews of the literature, served as the basis for this interpretation. The first case of poisoning concerns a 52-year-old man who for a short time (probably several hours), during the industrial cleaning of facilities with sodium hypochlorite, was exposed to chlorine in a presumed high concentration. The man was obese and suffered from hypertension and moderate atherosclerosis, and therefore could be more susceptible to the toxic effects of chlorine...
May 8, 2018: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29773297/the-clinical-practice-of-high-flow-nasal-cannula-oxygen-therapy-in-adults-a-japanese-cross-sectional-multicenter-survey
#6
Jiro Ito, Kazuma Nagata, Susumu Sato, Akira Shiraki, Naoki Nishimura, Shinyu Izumi, Ryo Tachikawa, Takeshi Morimoto, Keisuke Tomii
BACKGROUND: High-flow nasal cannula oxygen therapy (HFNC) is widely used mainly in the acute care setting, but limited data are available on real-world practice in adults. The objective of this study was to describe HFNC practices in Japanese adults. METHODS: A retrospective cross-sectional multicenter survey of adult patients receiving HFNC from January through March 2015 was conducted in 33 participating hospitals in Japan. RESULTS: We obtained information on 321 patients (median age, 76; 218 men, 103 women; median estimated PaO2 /FI O2, 178 mm Hg) from 22 hospitals...
May 2018: Respiratory Investigation
https://www.readbyqxmd.com/read/29764547/-comparison-of-lung-protection-for-hydrochloric-acid-or-oleic-acid-induced-rat-acute-respiratory-distress-syndrome-models-pretreated-with-penehyclidine
#7
Yumei Cheng, Zhou Yang, Feng Shen, Bo Liu, Yahui Wang, Yanqi Wu, Ling Yao, Yuqing Liu
OBJECTIVE: To compare the lung protection roles of intraperitoneal pre-injection with penehyclidine for two kinds of rat models with pulmonary and extrapulmonary acute respiratory distress syndrome (ARDSp and ARDSexp). METHODS: Forty healthy adult Sprague-Dawley (SD) rats were randomly divided into five groups (each n = 8): the rats in sham group received only tracheotomy; the ARDS rat models were reproduced by intratracheal inhalation of 0.1 mol/L hydrochloric acid (HCl) 2 mL/kg to simulate ARDSexp (HCl group) and 0...
May 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29763853/text-mining-and-network-analysis-to-find-functional-associations-of-genes-in-high-altitude-diseases
#8
Balu Bhasuran, Devika Subramanian, Jeyakumar Natarajan
BACKGROUND AND OBJECTIVES: Travel to elevations above 2500 m is associated with the risk of developing one or more forms of acute altitude illness such as acute mountain sickness (AMS), high altitude cerebral edema (HACE) or high altitude pulmonary edema (HAPE). Our work aims to identify the functional association of genes involved in high altitude diseases. METHOD: In this work we identified the gene networks responsible for high altitude diseases by using the principle of gene co-occurrence statistics from literature and network analysis...
May 2, 2018: Computational Biology and Chemistry
https://www.readbyqxmd.com/read/29753564/left-atrium-and-pulmonary-artery-compression-due-to-aortic-aneurysm-causing-heart-failure-symptoms
#9
Antonio José Lagoeiro Jorge, Wolney de Andrade Martins, Victor M Moutinho, Juliano M Rezende, Patricia Y Alves, Humberto Villacorta, Pedro F Silveira, Antonio A Couto
Patients with thoracic aortic aneurysm (TAA) are mostly asymptomatic and TAA is rarely related to heart failure (HF). We report the case of an 80-year-old female patient, with type A TAA without dissection, with right pulmonary artery and left atrium compression, who presented with HF, preserved ejection fraction and acute pulmonary edema.
May 9, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29750051/angiotensin-ii-type-2-receptor-agonist-compound-21-attenuates-pulmonary-inflammation-in-a-model-of-acute-lung-injury
#10
Mario Menk, Jan Adriaan Graw, Clarissa von Haefen, Hendrik Steinkraus, Burkhard Lachmann, Claudia D Spies, David Schwaiberger
Purpose: Although the role of the angiotensin II type 2 (AT2) receptor in acute lung injury is not yet completely understood, a protective role of this receptor subtype has been suggested. We hypothesized that, in a rodent model of acute lung injury, stimulation of the AT2 receptor with the direct agonist Compound 21 (C21) might have a beneficial effect on pulmonary inflammation and might improve pulmonary gas exchange. Materials and methods: Male adult rats were divided into a treatment group that received pulmonary lavage followed by mechanical ventilation (LAV, n=9), a group receiving pulmonary lavage, mechanical ventilation, and direct stimulation of the AT2 receptor with C21 (LAV+C21, n=9), and a control group that received mechanical ventilation only (control, n=9)...
2018: Journal of Inflammation Research
https://www.readbyqxmd.com/read/29749582/naloxone-induced-non-cardiogenic-pulmonary-edema-a-case-report
#11
Nasheena Jiwa, Himesh Sheth, Richard Silverman
A 22-year-old man was admitted for an elective right-shoulder open subacromial decompression and distal clavicle excision. He received a single intravenous dose of fentanyl 50 μg for anesthesia. His procedure was completed without intra-operative complications; however, he developed post-operative respiratory depression in the setting of narcotic administration. He was given naloxone 0.2 mg intravenously once to reverse this effect, which subsequently led to acute hypoxic respiratory failure secondary to pulmonary edema shortly after administration of naloxone...
May 10, 2018: Drug Safety—Case Reports
https://www.readbyqxmd.com/read/29743416/hemodilution-after-initial-treatment-in-patients-with-acute-decompensated-heart-failure
#12
Teppei Fujita, Takayuki Inomata, Mayu Yazaki, Yuichiro Iida, Toyoji Kaida, Yuki Ikeda, Takeru Nabeta, Shunsuke Ishii, Emi Maekawa, Tomoyoshi Yanagisawa, Toshimi Koitabashi, Ichiro Takeuchi, Junya Ako
Decongestion is an important goal of heart failure (HF) management. Blood cell concentration is a recognized indicator for guiding decongestive treatment for HF. We aimed to assess the clinical impact of hemodilution and hemoconcentration after initial treatment in acute decompensated HF (ADHF) patients. We retrospectively evaluated hemoglobin levels and body weight obtained before admission, on admission, 3 days after admission, and at discharge in 102 consecutive patients admitted with ADHF. Patients were then stratified into hemodilution (n = 55) and hemoconcentration (n = 47) groups based on whether their hemoglobin levels decreased or increased, respectively, during the first 3 days after admission...
May 9, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29743098/impact-of-flow-and-temperature-on-patient-comfort-during-respiratory-support-by-high-flow-nasal-cannula
#13
Tommaso Mauri, Alessandro Galazzi, Filippo Binda, Laura Masciopinto, Nadia Corcione, Eleonora Carlesso, Marta Lazzeri, Elena Spinelli, Daniela Tubiolo, Carlo Alberto Volta, Ileana Adamini, Antonio Pesenti, Giacomo Grasselli
BACKGROUND: The high-flow nasal cannula (HFNC) delivers up to 60 l/min of humidified air/oxygen blend at a temperature close to that of the human body. In this study, we tested whether higher temperature and flow decrease patient comfort. In more severe patients, instead, we hypothesized that higher flow might be associated with improved comfort. METHODS: A prospective, randomized, cross-over study was performed on 40 acute hypoxemic respiratory failure (AHRF) patients (PaO2 /FiO2  ≤ 300 + pulmonary infiltrates + exclusion of cardiogenic edema) supported by HFNC...
May 9, 2018: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29742212/accidental-strangulation-in-children-by-the-automatic-closing-of-a-car-window
#14
Kailene Serena, Jefferson Pedro Piva, Cinara Andreolio, Paulo Roberto Antonacci Carvalho, Tais Sica da Rocha
Among the main causes of death in our country are car accidents, drowning and accidental burns. Strangulation is a potentially fatal injury and an important cause of homicide and suicide among adults and adolescents. In children, its occurrence is usually accidental. However, in recent years, several cases of accidental strangulation in children around the world have been reported. A 2-year-old male patient was strangled in a car window. The patient was admitted to the pediatric intensive care unit with a Glasgow Coma Scale score of 8 and presented with progressive worsening of respiratory dysfunction and torpor...
March 2018: Revista Brasileira de Terapia Intensiva
https://www.readbyqxmd.com/read/29737632/mesenchymal-stem-cell-microvesicles-restore-protein-permeability-across-primary-cultures-of-injured-human-lung-microvascular-endothelial-cells
#15
Shuling Hu, Jeonghyun Park, Airan Liu, JaeHoon Lee, Xiwen Zhang, Qi Hao, Jae-Woo Lee
Our previous study demonstrated that mesenchymal stem cell (MSC) microvesicles (MV) reduced lung inflammation, protein permeability, and pulmonary edema in endotoxin-induced acute lung injury in mice. However, the underlying mechanisms for restoring lung protein permeability were not fully understood. In this current study, we hypothesized that MSC MV would restore protein permeability across injured human lung microvascular endothelial cells (HLMVEC) in part through the transfer of angiopoietin-1 (Ang1) mRNA to the injured endothelium...
May 8, 2018: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/29722341/halogen-inhalation-induced-lung-injury-and-acute-respiratory-distress-syndrome
#16
REVIEW
Ting Zhou, Wei-Feng Song, You Shang, Shang-Long Yao, Sadis Matalon
Objective: Exposure to halogens, such as chlorine or bromine, results in environmental and occupational hazard to the lung and other organs. Chlorine is highly toxic by inhalation, leading to dyspnea, hypoxemia, airway obstruction, pneumonitis, pulmonary edema, and acute respiratory distress syndrome (ARDS). Although bromine is less reactive and oxidative than chlorine, inhalation also results in bronchospasm, airway hyperresponsiveness, ARDS, and even death. Both halogens have been shown to damage the systemic circulation and result in cardiac injury as well...
May 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29721920/acquired-peripheral-pulmonary-artery-aneurysms-morphological-spectrum-of-disease-and-multidetector-computed-tomography-angiography-findings-cases-series-and-literature-review
#17
REVIEW
Tullio Valente, Ahmad Abu-Omar, Giacomo Sica, Alfredo Clemente, Massimo Muto, Giorgio Bocchini, Salvatore Cappabianca, Gaetano Rea
BACKGROUND: Acquired peripheral or intraparenchymal pulmonary artery aneurysms (PPAA) are rare entities but are important to recognize because of the associated morbidity. Hemoptysis is their principal complication and is a potentially fatal condition. PURPOSE: To illustrate the causes, multidetector CT angiography (MDCTA) findings and differential diagnosis of acquired PPAA. MATERIALS AND METHODS: The institutional review boards approved this study...
May 2, 2018: La Radiologia Medica
https://www.readbyqxmd.com/read/29719782/beneficial-effects-of-houttuynia-cordata-polysaccharides-on-two-hit-acute-lung-injury-and-endotoxic-fever-in-rats-associated-with-anti-complementary-activities
#18
Yan Lu, Yun Jiang, Lijun Ling, Yunyi Zhang, Hong Li, Daofeng Chen
Houttuynia cordata Thunb. is a traditional herb used for clearing heat and eliminating toxins, and has also been used for the treatment of severe acute respiratory syndrome (SARS). In vitro, the crude H. cordata polysaccharides (CHCP) exhibited potent anti-complementary activity through both the classical and alternative pathways by acting on components C3 and C4 of the complement system without interfering with the coagulation system. This study was to investigate the preventive effects of CHCP on acute lung injury (ALI) induced by hemorrhagic shock plus lipopolysaccharide (LPS) instillation (two-hit) and LPS-induced fever in rats...
March 2018: Acta Pharmaceutica Sinica. B
https://www.readbyqxmd.com/read/29717986/aortic-dissecting-aneurysm-associated-with-systemic-arterial-hypertension-in-a-cat
#19
V Gouni, S Papageorgiou, J Debeaupuits, C Damoiseaux, J Pouchelon, V Chetboul
Aortic dissection is characterized by a tear in the aortic wall resulting in blood from the aortic lumen penetrating into the media, which causes dissection. When aortic dissection does not cause rupture, it provokes localized dilation of the aorta or aneurism, also called dissecting aortic aneurism (DAA). This case report describes a DAA in a cat associated with systemic arterial hypertension (SAHT). A 10-year-old male Domestic shorthair cat was presented for cardiac evaluation. Anamnestic clinical complaints were a syncope associated with paraparesis and weak femoral pules...
May 2018: Schweizer Archiv Für Tierheilkunde
https://www.readbyqxmd.com/read/29715123/takotsubo-cardiomyopathy-developed-after-two-stage-surgery-for-double-primary-lung-cancer
#20
Fumihiko Kinoshita, Gouji Toyokawa, Tetsuzo Tagawa, Taichi Matsubara, Yuka Kozuma, Naoki Haratake, Shinkichi Takamori, Takaki Akamine, Fumihiko Hirai, Yoshihiko Maehara
Takotsubo cardiomyopathy (TC) is a syndrome characterized by transient local systolic dysfunction of the left ventricle with no evidence of coronary artery disease or acute plaque rupture. We present the case of 71-year-old woman who developed TC after two-stage surgery for double primary lung cancer. On computed tomography, lung nodules were identified in the left upper and right middle lobes. Based on the diagnosis of double primary lung cancer, we performed two-stage surgery (left upper lobectomy followed by right middle lobectomy)...
May 2018: Anticancer Research
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