Read by QxMD icon Read


Aldo Bruno, Marisanta Napolitano, Luigi Califano, Giuseppe Attanasio, Vincenzo Giugliano, Pier Paolo Cavazzuti, Marika Viccaro, Eleonora Masci, Diego Mastrangelo, Francesca Salafia, Salvatore Mazzone, Benedetto Bernardo, Laura Cagnoni, Roberto Filipo, Marco De Vincentis, Antonio Greco
PURPOSE: To evaluate relationship between Meniere disease (MD) and chronic cerebrospinal venous insufficiency (CCSVI) using ultrasound, magnetic resonance (MR) imaging, and venography and to evaluate the effectiveness of angioplasty of the internal jugular vein (IJV) and azygos vein (AV) in reducing symptoms of MD. MATERIALS AND METHODS: Patients with a confirmed diagnosis of MD unresponsive to standard treatment underwent duplex ultrasound and MR imaging to diagnose CCSVI...
December 26, 2016: Journal of Vascular and Interventional Radiology: JVIR
Giuseppe Attanasio, Laura Cagnoni, Eleonora Masci, Francesco Ciciarello, Francesco Diaferia, Aldo Bruno, Antonio Greco, Marco De Vincentiis
CONCLUSION: The present study confirms a correlation between chronic cerebrospinal venous insufficiency (CCSVI) diagnosis and Ménière's disease (MD). CCSVI could be considered a new ultrasound vascular pattern of the cerebrospinal venous system in patients affected by definite MD. Conversely, the present results showed that CCSVI cannot be considered a pathogenic mechanism for idiopathic sudden sensorineural hearing loss (ISSNHL). OBJECTIVES: The aim of this study is to investigate the correlation between CCSVI and MD and to evaluate if CCSVI can be considered a risk factor also for ISSNHL...
November 16, 2016: Acta Oto-laryngologica
Aldo Bruno, Gennaro Quarto, Luigi Califano, Diego Mastrangelo, Marcella De Vizia, Francesca Salafia, Benedetto Bernardo
PURPOSE: The authors have evaluated by ultrasound the CCSVI in Meniere's Disease. MATERIALS AND METHODS: 140 patients with diagnosis of Meniere's Disease, who have had not improvement to usual therapy, underwent echo color Doppler sonografy by Zamboni's protocol for the diagnosis of CCSVI . 128 were positive. RESULTS: Ultrasound diagnosis of CCSVI was performed in patients with Meniere's Disease with a positivity in 128 patients on 140 examinated (90% of cases)...
2016: Annali Italiani di Chirurgia
Gabriela Cardaioli, Massimiliano Di Filippo, Alessia Bianchi, Paolo Eusebi, Maria Di Gregorio, Lorenzo Gaetani, Antongiulio Gallina, Paolo Calabresi, Paola Sarchielli
The etiology of multiple sclerosis (MS) is still largely unknown and it has been proposed that an impaired venous drainage from the central nervous system, defined as chronic cerebrospinal venous insufficiency (CCSVI), may play a role in this. We investigated the prevalence of extracranial venous drainage pattern alterations in a cohort of MS patients based on the 2011 revised diagnostic criteria for CCSVI. Thirty-nine MS patients and 18 healthy subjects underwent blinded extra-cranial venous echo-color Doppler sonography to reveal the presence of CCSVI...
2016: European Neurology
M Paoletti, G Germani, R De Icco, C Asteggiano, P Zamboni, S Bastianello
Scientific debate over chronic cerebrospinal venous insufficiency (CCSVI) has drawn attention to venous system involvement in a series of pathologic brain conditions. In the last few decades, the MRI venography (MRV) field has developed a number of valuable sequences to better investigate structural anatomy, vessel patency, and flow characteristics of venous drainage in the intra- and extracranial systems. A brief two-tier protocol is proposed to encompass the study of intra- and extracranial venous drainage with and without contrast administration, respectively...
2016: Behavioural Neurology
Sandro Mandolesi, Alessandro d'Alessandro, Tarcisio Niglio, Aldo Bruno, Benedetto Bernardo, Dimitri Mandolesi, Antonella Caroli, Aldo d'Alessandro, Francesco Fedele
OBJECTIVES: Aims of this study were to investigate the prevalence of reflux on internal jugular veins(IJV) by Valsalva maneuver and to define the association between reflux of IJV in subjects with both CCSVI and MS. METHODS: We recruited 393 patients with MS and CCSVI. Study participants underwent EchoColor Doppler exam in order to define IJV diameter at confluence in subclavian (JSd). Subjects were divided in three groups: group "1<JSd<6 mm" (subjects with jugular diameter less than 6mm); group "6≤JSd<10 mm" (subjects with jugular diameter equal or more than 6 but less than 10); and group "JSd≥10 mm" (subjects with jugular diameter equal or more than 10 mm)...
2016: Annali Italiani di Chirurgia
Setareh Ghahari, Susan J Forwell
BACKGROUND: We conducted a rigorous review of videos related to multiple sclerosis (MS) and chronic cerebrospinal venous insufficiency (CCSVI) treatment posted by people with MS on one social media website (YouTube) that describe symptoms before and after the surgical procedure, as well as videos presented by health-care professionals (HCPs). METHODS: All relevant videos posted from December 2009 to July 2011 were downloaded, viewed, and systematically organized...
March 2016: International Journal of MS Care
Luanne M Metz, Jamie Greenfield, Ruth Ann Marrie, Nathalie Jette, Gregg Blevins, Lawrence W Svenson, Katayoun Alikhani, Winona Wall, Raveena Dhaliwal, Oksana Suchowersky
BACKGROUND: Many Canadians with multiple sclerosis (MS) have recently travelled internationally to have procedures for a putative condition called chronic cerebrospinal venous insufficiency (CCSVI). Here, we describe where and when they went and describe the baseline characteristics of persons with MS who participated in this non-evidence-based medical tourism for CCSVI procedures. METHODS: We conducted a longitudinal observational study that used online questionnaires to collect patient-reported information about the safety, experiences, and outcomes following procedures for CCSVI...
May 2016: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
Sandro Mandolesi, Giuseppe Marceca, Aldo d'Alessandro, Antonello Desogus, Matteo Marco Ciccone, Annapaola Zito, Ettore Manconi, Tarcisio Niglio, Dimitri Mandolesi, Alessandro d'Alessandro, Francesco Fedele
PURPOSE: The complete compression of the internal jugular veins, in front position, shows a prevalence of 48% and it is equally distributed in the various segments of these veins in patients with Chronic Cerebro-Spinal Venous Insufficiency (CCSVI) and Multiple Sclerosis (MS). The aim of this search is to identify radiological dislocation of C1-C2 as specific markers in patients with CCSVI and Multiple Sclerosis (MS). METHOD: We investigated 386 patients suffering from CCSVI and Multiple Sclerosis and a control group of 156 patients without MS...
July 2015: Annali Italiani di Chirurgia
Aldo d'Alessandro, Tarcisio Niglio, Antonello Desogus, Alessandro d'Alessandro, Dimitri Mandolesi
A Multiple Sclerosis patient with chronic cerebrospinal venous insufficiency (CCSVI) treated by acoustic waves, modulated in frequency and power of the Dreno-MAM® device, showed a progressive improvement in motor coordination, resistance to work, muscular power and rigidity, and distal microcirculation. Life quality, chronic fatigue, and clinical severity questionnaires EDSS show marked improvements with a follow-up of two years. We suggest that the method could be also used in the chronic fatigue syndrome and other neurological diseases such as Parkinson or Meniere syndrome...
July 2015: Annali Italiani di Chirurgia
Sandro Mandolesi, Giuseppe Marceca, Jon Moser, Tarcisio Niglio, Aldo d'Alessandro, Matteo Marco Ciccone, Annapaola Zito, Dimitri Mandolesi, Alessandro d'Alessandro, Francesco Fedele
PURPOSE: The aim of the study is to evaluate the clinical and X-ray results of the Upper Cervical Chiropractic care through the specific adjustments (corrections) of C1-C2 on patients with chronic venous cerebral-spinal insufficiency (CCSVI) and multiple sclerosis (MS). METHOD: We studied a sample of 77 patients before and after the Upper Cervical Chiropractic care, and we analyzed: A) The change of the X-ray parameters; B) The clinical results using a new set of questions...
May 2015: Annali Italiani di Chirurgia
Janka Koschack, Lara Weibezahl, Tim Friede, Wolfgang Himmel, Philip Makedonski, Jens Grabowski
BACKGROUND: The vascular hypothesis of multiple sclerosis (MS), called chronic cerebrospinal venous insufficiency (CCSVI), and its treatment (known as liberation therapy) was immediately rejected by experts but enthusiastically gripped by patients who shared their experiences with other patients worldwide by use of social media, such as patient online forums. Contradictions between scientific information and lay experiences may be a source of distress for MS patients, but we do not know how patients perceive and deal with these contradictions...
2015: Journal of Medical Internet Research
L O Müller, E F Toro, E M Haacke, D Utriainen
BACKGROUND: The presence of abnormal anatomy and flow in neck veins has been recently linked to neurological diseases. The precise impact of extra-cranial abnormalities such as stenoses remains unexplored. METHODS: Pressure and velocity fields in the full cardiovascular system are computed by means of a global mathematical model that accounts for the relationship between pulsating cerebral blood flow and intracranial pressure. RESULTS: Our model predicts that extra-cranial strictures cause increased pressure in the cerebral venous system...
June 2016: Phlebology
Zohara Sternberg
Accumulated evidence suggests that cardiovascular autonomic nervous system (ANS) dysfunction may be the underlying cause of many MS clinical presentations, including neurodegeneration and reduced response to immunomodulatory therapies, depression, fatigue and sleep disorders, migraine, osteoporosis, and chronic cerebrospinal venous insufficiency, the newer MS vascular etiology. We have recently described the genetic, epigenetic, and environmental factors with the potential influencing ANS activity, and the interactions among these factors...
February 2016: Autoimmunity Reviews
Christos Krogias, Ralf Gold, Andrew Chan, Nikos Triantafyllou, Konstantinos Voumvourakis, Georgios Tsivgoulis
BACKGROUND AND PURPOSE: The "venous hypothesis" of multiple sclerosis (MS) postulates that intracranial venous congestion disintegrates the blood-brain barrier, resulting in iron accumulation in brain parenchyma triggering the inflammatory process of MS. Transcranial sonography (TCS) reveals brain parenchyma hyperechogenic alterations (BPHA) that are thought to reflect iron accumulation. We sought to investigate potential association of BPHA with chronic cerebrospinal venous insufficiency (CCSVI) in MS...
January 2016: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
Michelle Ploughman, Olivia J Manning, Serge Beaulieu, Chelsea Harris, Stephen H Hogan, Nancy Mayo, John D Fisk, A Dessa Sadovnick, Paul O'Connor, Sarah A Morrow, Luanne M Metz, Penelope Smyth, Penelope W Allderdice, Susan Scott, Ruth Ann Marrie, Mark Stefanelli, Marshall Godwin
BACKGROUND: Following the initial reports of Chronic Cerebrospinal Venous Insufficiency (CCSVI) and the purported curative potential of venoplasty, (coined the 'liberation' procedure) Canadians living with multiple sclerosis (MS) began to travel abroad to receive the unregulated procedure, often placing them at odds with their health providers. The purpose of this study was to determine the factors influencing older MS patients' decision to undergo the procedure in order to develop more specific and targeted health information...
2015: BMC Health Services Research
Arie R Gafson, Gavin Giovannoni
In 2008, Paulo Zamboni pioneered the 'liberation procedure' for treating multiple sclerosis (MS), claiming that MS is caused by an abnormality of venous drainage which he called chronic cerebrospinal venous insufficiency (CCSVI). CCSVI has been very controversial, both socio-politically and scientifically after going 'viral' via social media. In late 2012, only 56 original scientific research papers had been published on the 'CCSVI syndrome'; however, over 1,150,000 hits on Google existed when searching for the term 'chronic cerebrospinal venous insufficiency' or CCSVI...
March 2014: Multiple Sclerosis and related Disorders
M Arata, Z Sternberg
Balloon angioplasty (BA) is a treatment modality to correct vascular lesions in multiple sclerosis (MS) patients, who present with chronic cerebrospinal venous insufficiency (CCSVI). We hypothesized that BA clinical benefits stems in part from improvement in cardiovascular autonomic nervous system (ANS) function. We adopted the Transvascular Autonomic Modulation (TVAM), as a modified BA technique, with the objective of further enhancing ANS functional activities. TVAM involved dilation of multiple vascular beds, including IJVs, azygos and renal veins, and application of manual compression...
February 2016: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
Georgios Tsivgoulis, Simon Faissner, Konstantinos Voumvourakis, Aristeidis H Katsanos, Nikos Triantafyllou, Nikolaos Grigoriadis, Ralf Gold, Christos Krogias
BACKGROUND: Chronic cerebrospinal venous insufficiency (CCSVI) has recently been introduced as a chronic state of impaired cerebral or cervical venous drainage that may be causally implicated in multiple sclerosis (MS) pathogenesis. Moreover, percutaneous transluminal angioplasty of extracranial veins termed "Liberation treatment" has been proposed (based on nonrandomized data) as an alternative therapy for MS. METHODS: A comprehensive literature search was conducted to identify available published, peer-reviewed, clinical studies evaluating (1) the association of CCSVI with MS, (2) the reproducibility of proposed ultrasound criteria for CCSVI detection (3) the safety and efficacy of "Liberation treatment" in open-label and randomized-controlled trial (RCT) settings...
January 2015: Brain and Behavior
A V Peresedova, A O Chechetkin, M A Lebedeva, L Sh Askarova, I A Zavalishin
Objective. To evaluate the jugular veins (IJV) using duplex sonography in patients with multiple sclerosis (MS). Material and methods. The study included 21 MS patients with different disease course, degree of disability and disease duration. A control group consisted of 8 healthy volunteers. Results. IJV changes that meet the CCSVI criteria have not been found. These findings are consistent with the results of recently published large studies. Possible reasons of non-confirmation of this hypothesis are discussed...
2014: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"