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https://www.readbyqxmd.com/read/29241276/multiband-mucosectomy-for-the-treatment-of-challenging-non-pedunculated-colorectal-polyps
#1
Joaquín Rodríguez-Sánchez, Eva De la Santa Belda, Pilar Olivencia Palomar, Margarita Úbeda Muñoz, José Olmedo Camacho
Background and study aims Endoscopic mucosal resection is the gold standard treatment for non-pedunculated colorectal polyps; however, some specific situations (location behind folds, scarred or flat morphology) can make this technique challenging. We aimed to assess the efficacy and safety of multiband mucosectomy (MBM) for resection of non-pedunculated colorectal polyps. Patients and methods This was a retrospective study of patients in whom MBM was performed to resect large non-pedunculated colorectal polyps...
December 14, 2017: Endoscopy
https://www.readbyqxmd.com/read/29241156/incidence-of-cutaneous-malignant-melanoma-in-iranian-provinces-and-american-states-matched-on-ultraviolet-radiation-exposure-an-ecologic-study
#2
Roxana Moslehi, Nur Zeinomar, Francis P Boscoe
OBJECTIVES: Ultraviolet radiation (UVR), with UVB and UVA as the relevant components, is a risk factor for melanoma. Complete ascertainment and registration of melanoma in Iran was conducted in five provinces (Ardabil, Golestan, Mazandaran, Gilan and Kerman) during 1996-2000. The aim of our study was to compare population-based incidence data from these provinces with rates in the United States (US) while standardizing ambient UVR. METHODS: Population-based rates representing all incident cases of melanoma (1996-2000) across the five Iranian provinces were compared to rates of melanoma among white non-Hispanics in the US...
December 11, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29241152/thoracoamniotic-shunting-for-fetal-pleural-effusion-with-hydropic-change-using-a-double-basket-catheter-an-insight-into-the-preoperative-determinants-of-shunting-efficacy
#3
Nobuhiro Hidaka, Saki Kido, Yuka Sato, Masaharu Murata, Yasuyuki Fujita, Kiyoko Kato
OBJECTIVES: Although the efficacy of thoracoamniotic shunting (TAS) for fetal hydrothorax is well-recognized, the coexistence of hydrops fetalis is still a clinical challenge. The preoperative determinants of shunting efficacy are not fully understood. In this study, we aimed to investigate the perinatal and postnatal outcomes of hydrops fetalis with pleural effusion treated by TAS using a double-basket catheter, and to discuss the preoperative factors predictive of patients who will benefit from TAS...
December 7, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29241099/perceptual-motor-regulation-in-locomotor-pointing-while-approaching-a-curb
#4
Steven van Andel, Michael H Cole, Gert-Jan Pepping
Locomotor pointing is a task that has been the focus of research in the context of sport (e.g. long jumping and cricket) as well as normal walking. Collectively, these studies have produced a broad understanding of locomotor pointing, but generalizability has been limited to laboratory type tasks and/or tasks with high spatial demands. The current study aimed to generalize previous findings in locomotor pointing to the common daily task of approaching and stepping on to a curb. Sixteen people completed 33 repetitions of a task that required them to walk up to and step onto a curb...
December 9, 2017: Gait & Posture
https://www.readbyqxmd.com/read/29241084/neoadjuvant-radiotherapy-combined-with-capecitabine-and-sorafenib-in-patients-with-advanced-kras-mutated-rectal-cancer-a-phase-i-ii-trial-sakk-41-08
#5
Roger von Moos, Dieter Koeberle, Sabina Schacher, Stefanie Hayoz, Ralph C Winterhalder, Arnaud Roth, György Bodoky, Panagiotis Samaras, Martin D Berger, Daniel Rauch, Piercarlo Saletti, Ludwig Plasswilm, Daniel Zwahlen, Urs R Meier, Pu Yan, Paola Izzo, Dirk Klingbiel, Daniela Bärtschi, Kathrin Zaugg
BACKGROUND: KRAS mutation occurs in ∼40% of locally advanced rectal cancers (LARCs). The multitarget tyrosine kinase inhibitor sorafenib has radiosensitising effects and might improve outcomes for standard preoperative chemoradiotherapy in patients with KRAS-mutated LARC. METHODS: Adult patients with KRAS-mutated T3/4 and/or N1/2M0 LARC were included in this phase I/II study. The phase I dose-escalation study of capecitabine plus sorafenib and radiotherapy was followed by a phase II study assessing efficacy and safety...
December 11, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/29241077/pectoral-nerve-blocks-to-improve-analgesia-after-breast-cancer-surgery-a-prospective-randomized-and-controlled-trial
#6
Neethu M, Ravinder Kumar Pandey, Ankur Sharma, Vanlalnghaka Darlong, Jyotsna Punj, Renu Sinha, Preet Mohinder Singh, Nandini Hamshi, Rakesh Garg, Chandralekha Chandralekha, Anurag Srivastava
STUDY OBJECTIVE: To evaluate the analgesic efficacy of ultrasound guided combined pectoral nerve blocks I and II in patients scheduled for surgery for breast cancer. DESIGN: Prospective, randomized, control trial. SETTING: Operating rooms in a tertiary care hospital of Northern India. PATIENTS: Sixty American Society of Anesthesiologists status I to II adult women, aged 18-70years were enrolled in this study. INTERVENTIONS: Patients were randomized into two groups (30 patients in each group), PECS (P) group and control (C) group...
December 11, 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/29241047/knee-misalignment-and-exercise-amount-predictive-value-for-chronic-low-back-pain-in-young-competitive-athletes
#7
Andreas Rosenhagen, Daniel Niederer, Lutz Vogt, Winfried Banzer
Sports medical examinations of juvenile athletes provide an opportunity for preventive measures against sports-related diseases. Determining the leg axis deviation as a risk factor for future constraints may offer approaches for such measures. Data were obtained from 789 youth athletes: 166 with coronal plane knee misalignment and 623 without. After a seven-year period, 64 participants (m: 33, f: 31) from both groups were reassessed for the incidence of nonspecific chronic low back pain (CLBP). To distinguish participants with increased risk for CLBP, contingency tables for comparison of expected and joint frequency distribution testing and receivers operating characteristic (ROC) analyses for the weekly training time were conducted...
December 11, 2017: Human Movement Science
https://www.readbyqxmd.com/read/29240992/heart-rate-recovery-and-diastolic-blood-pressure-ratio-on-the-treadmill-test-predict-an-induction-and-recurrence-of-vasovagal-syncope
#8
Yu Jeong Choi, Ki-Woon Kang, Sang Hyun Jang, Jae Guk Kim, Soo Joo Lee, Kyung Tea Jung
Background/Aims: The induction and recurrence of syncope is a concerning situation that could be unpredicted in the vasovagal syncope (VVS). We investigated a simple predictor for the induced and recurrent VVS during Head-Up table-tilt Test (HUT) and clinically follow-up. Methods: The 143 consecutive patients with VVS (age 31 ± 19 years, 33 male) who referred by a cardiologist or neurologist and had undergone an echocardiogram, HUT, and a treadmill exercise test (TMT) were recruited and clinically follow-up...
December 18, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29240976/clopidogrel-plus-aspirin-versus-aspirin-alone-for-preventing-cardiovascular-events
#9
REVIEW
Alessandro Squizzato, Marta Bellesini, Andrea Takeda, Saskia Middeldorp, Marco Paolo Donadini
BACKGROUND: Aspirin is the prophylactic antiplatelet drug of choice for people with cardiovascular disease. Adding a second antiplatelet drug to aspirin may produce additional benefit for people at high risk and people with established cardiovascular disease. This is an update to a previously published review from 2011. OBJECTIVES: To review the benefit and harm of adding clopidogrel to aspirin therapy for preventing cardiovascular events in people who have coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease, or were at high risk of atherothrombotic disease, but did not have a coronary stent...
December 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29240900/evaluation-of-differential-pulmonary-perfusion-using-99mtc-macroaggregated-albumin-after-the-fontan-procedure
#10
Sachin Talwar, Lakshmi Sankhyan, Chetan Patel, Vishnubhatla Sreenivas, Shiv Kumar Choudhary, Balram Airan
OBJECTIVES: The Fontan procedure [total cavopulmonary connection (TCPC)] is the final palliation for patients with univentricular physiology. We studied differential perfusion ratio and percentage uptake of a radiotracer in different zones of each lung following TCPC. METHODS: Between July 2015 and June 2017, 45 patients underwent 99mTc macroaggregated albumin lung perfusion scan at a mean follow-up period of 49.3 ± SD 26.1 days following TCPC. Differential perfusion ratio and percentage uptake of the radiotracer in the upper, middle and lower zones of each lung were calculated...
December 11, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29240803/bone-edema-on-magnetic-resonance-imaging-is-highly-associated-with-low-bone-mineral-density-in-patients-with-ankylosing-spondylitis
#11
Danmin Wang, Zhiduo Hou, Yao Gong, Subiao Chen, Ling Lin, Zhengyu Xiao
OBJECTIVE: This study aimed to assess the relationship between bone marrow edema (BME) on magnetic resonance imaging (MRI) and bone mineral density (BMD) in patients with ankylosing spondylitis (AS). METHODS: The study included 333 patients with AS who underwent BMD measurements and axial MRI. Additionally, 106 normal controls were included. The modified New York criteria were used as the classification criteria of AS. Clinical, laboratory, and imaging data were collected and analyzed...
2017: PloS One
https://www.readbyqxmd.com/read/29240742/paediatric-testicular-tumours-in-a-new-zealand-centre
#12
Timothy Little, Shareena Lala, Vipul Upadhyay
AIM: This is a 12-year, single-centre retrospective review of paediatric testicular tumours and review of the world literature on paediatric testicular tumours. The aim was to identify presenting features, the range of pathology and management of such tumours in comparison with other published series. METHODS: The hospital's pathology database was searched for all testicular and paratesticular tissue submitted for patients younger than 16 years of age during the 12-year study period January 2000 to December 2011, and patients with testicular tumours identified...
December 15, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29240740/characteristics-of-and-differences-between-pasifika-women-and-new-zealand-european-women-diagnosed-with-breast-cancer-in-new-zealand
#13
Charis Brown, Chunhuan Lao, Ross Lawrenson, Sandar Tin Tin, Michelle Schaaf, Jacquie Kidd, Anne Allan-Moetaua, Josephine Herman, Reena Raamsroop, Ian Campbell, Mark Elwood
AIM: Breast cancer in New Zealand-based Pasifika women is a significant issue. Although Pasifika women have a lower incidence of breast cancer compared to New Zealand European women, they have higher breast cancer mortality and lower five-year survival. The aim of this study was to describe the characteristics and tumour biology of Pasifika women and to compare New Zealand European women to identify what factors impact on early (Stage 1 and 2) vs advanced stage (Stage 3 and 4) at diagnosis...
December 15, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29240646/genetic-and-environmental-contributions-to-sleep-quality-and-low-back-pain-a-population-based-twin-study
#14
Marina B Pinheiro, Jose J Morosoli, Manuela L Ferreira, Juan J Madrid-Valero, Kathryn Refshauge, Paulo H Ferreira, Juan R Ordoñana
OBJECTIVE: To estimate the extent to which the co-occurrence of poor sleep quality and low back pain is due to the same genetic and/or environmental risk factors or due to a causal association. METHODS: Cross-sectional data on sleep quality (Pittsburgh Sleep Quality index) and low back pain were collected in a population-based sample of adult twins (n=2,134) registered with the Murcia Twin Registry. Bivariate analysis and structural equation modelling were used...
December 13, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/29240627/extracorporeal-membrane-oxygenation-bridges-inoperable-patients-to-definitive-cardiac-operation
#15
Nikola Dobrilovic, Omar Lateef, Lauren Michalak, Maja Delibasic, Jaishankar Raman
Extracorporeal membrane oxygenation (ECMO) offers an opportunity for patient recovery through complete cardiopulmonary support but is associated with complications that limit duration and overall utility. We examine the role of ECMO as a potential bridge to high-risk cardiac surgery in otherwise inoperable cases. This study reports a retrospective, multi-institution experience examining all patients for whom ECMO was used preoperatively as a bridge to definitive cardiac surgery without exception. A consecutive patient database (December 2011 through August 2017) was utilized...
December 11, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29240613/assessing-the-knowledge-skills-and-abilities-of-public-health-professionals-in-big-city-governmental-health-departments
#16
Meghan D McGinty, Brian C Castrucci, Debra M Rios
OBJECTIVE: To identify essential knowledge, skills, and abilities (KSAs) for and characterize gaps in KSAs of professionals working in large, urban health departments. DESIGN: A survey was disseminated to potentially eligible supervisors within 26 of 28 health departments in the largest, most urban jurisdictions in the country. A supervisor was eligible to participate if he or she supervised at least 1 staff member whose highest level of education was a master's degree...
December 13, 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/29240602/unclassified-variants-of-brca1-and-brca2-in-korean-patients-with-ovarian-cancer
#17
Min Chul Choi, Ja-Hyun Jang, Sang Geun Jung, Hyun Park, Won Duk Joo, Seung Hun Song, Chan Lee, Je Ho Lee
OBJECTIVE: The aim of the present study was to investigate unclassified variants (UVs) in BRCA1 and 2 of Korean patients with ovarian cancer. METHODS: We retrospectively analyzed 138 patients diagnosed with ovarian/fallopian tubal/peritoneal cancer between January 2013 and January 2016, whose BRCA genetic test results and clinical characteristics were available for review. Patient peripheral blood lymphocyte specimens were assessed for BRCA mutations and variations by direct sequencing...
December 13, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29240598/intraluminal-deposits-found-in-glaucoma-tube-shunts-via-anterior-segment-ocular-coherence-tomography
#18
Jorge A Alvarado, Vinita Srivastava, Yang Sun
PURPOSE: To describe and characterize a novel observation of intraluminal deposits of glaucoma tube shunts (TS) using spectral domain (SD) ocular coherence topography (OCT). PATIENTS AND METHODS: Fifteen TS in 11 patients diagnosed with primary open angle, neovascular, aphakic, and uveitic glaucomas. Both Ahmed (n=11) and Baerveldt (n=4) TS were examined with 5-line raster anterior segment SD-OCT imaging. RESULTS: The exposed tubes of two patients had highly reflective intraluminal deposits in the corresponding exposed areas...
December 13, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29240565/platelets-to-lymphocyte-ratio-is-a-good-predictor-of-liver-fibrosis-and-insulin-resistance-in-hepatitis-c-virus-related-liver-disease
#19
Ayman Alsebaey, Mostafa Elhelbawy, Imam Waked
BACKGROUND: Hepatitis C virus (HCV) is a global health problem that is complicated by liver fibrosis and insulin resistance (IR). AIM: The aim of this study was to validate neutrophils-to-lymphocytes ratio (NLR) and platelets-to-lymphocytes ratio (PLR) as indirect biomarkers of liver fibrosis and IR in HCV patients. PATIENTS AND METHODS: One hundred and fifty patients were enrolled. Physical examination, BMI, liver function tests, serum creatinine, complete blood count, serum HCV RNA count by PCR, and abdominal ultrasonography were performed...
December 13, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29240268/assessment-of-procoagulant-potential-in-patients-with-reactive-thrombocytosis-and-its-association-with-platelet-count
#20
Amihai Rottenstreich, Ela Shai, Geffen Kleinstern, Galia Spectre, David Varon, Yosef Kalish
OBJECTIVE: We aimed to determine hemostatic changes and characterize the procoagulant potential among reactive thrombocytosis (RT) patients. METHODS: Sixty RT patients (median platelet count 718X109 /L) and 20 healthy persons were tested for complete blood count, C-reactive protein, von Willebrand factor (VWF), factor VIII and fibrinogen, and thrombin generation. Platelet studies, including light transmission aggregometry and Cone and Plate(let) Analyzer, were also conducted...
December 14, 2017: European Journal of Haematology
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