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Don poldermans

Don Poldermans
No abstract text is available yet for this article.
June 2013: European Heart Journal
Vineet Chopra, Kim A Eagle
Recent allegations of fraud committed by one of the most prolific researchers in perioperative medicine, Don Poldermans, have left many clinicians in a state of disbelief. With over 500 peer-reviewed publications, Poldermans heavily influenced the clinical practice of perioperative beta-blockers and statins in noncardiac surgery, shaping guidelines and national policies on the use of these treatments. The effects of fraud in perioperative medicine are particularly caustic owing to a profound domino effect. Many investigators devoted their academic careers to following the footsteps of investigators such as Poldermans...
October 2012: American Journal of Medicine
Chiara Pedone, Abdou Elhendy, Ron T van Domburg, Stefan P Nelwan, Elena Biagini, Giuseppe Di Pasquale, Jeroen J Bax, Don Poldermans
OBJECTIVE: The aim of this study was to determine whether resting ST-T wave abnormalities (ST-Ta) provide incremental prognostic information in patients with no history of coronary artery disease undergoing dobutamine stress echocardiography (DSE). METHODS: We evaluated 1308 consecutive patients without previous myocardial infarction (MI) or revascularization who underwent DSE. Ischemia was defined as new or worsening wall motion abnormalities. End points during follow-up were all-cause death and cardiac death/nonfatal MI...
December 2011: Coronary Artery Disease
Radosav Vidaković, Don Poldermans, Aleksandar N Nesković
Approximately 100 million people undergo noncardiac surgery annually worldwide. It is estimated that around 3% of patients undergoing noncardiac surgery experience a major adverse cardiac event. Although cardiac events, like myocardial infarction, are major cause of perioperative morbidity or mortality, its true incidence is difficult to assess. The risk of perioperative cardiac complications depends mainly on two conditions: (1) identified risk factors, and (2) the type of the surgical procedure. On that basis, different scoring systems have been developed in order to accurately assess the perioperative cardiac risk and to improve the patient management...
2011: Acta Chirurgica Iugoslavica
Michal Tendera, Victor Aboyans, Marie-Louise Bartelink, Iris Baumgartner, Denis Clément, Jean-Philippe Collet, Alberto Cremonesi, Marco De Carlo, Raimund Erbel, F Gerry R Fowkes, Magda Heras, Serge Kownator, Erich Minar, Jan Ostergren, Don Poldermans, Vincent Riambau, Marco Roffi, Joachim Röther, Horst Sievert, Marc van Sambeek, Thomas Zeller
No abstract text is available yet for this article.
November 2011: European Heart Journal
Felix van Lier, Patrick J van der Geest, Sanne E Hoeks, Yvette R B M van Gestel, Jaap W Hol, Don D Sin, Robert Jan Stolker, Don Poldermans
BACKGROUND: Patients with chronic obstructive pulmonary disease (COPD) have increased postoperative morbidity and mortality. Epidural analgesia (EDA) improves postoperative outcome but may worsen postoperative lung function. It is unknown whether patients with COPD benefit from EDA. The objective of this study was to determine whether patients with COPD undergoing major abdominal surgery benefit from EDA in addition to general anesthesia. METHODS: This cohort study included 541 consecutive patients with COPD who underwent major abdominal surgery between 1995 and 2007 at a university medical center...
August 2011: Anesthesiology
Sanne E Hoeks, Elise Bouw, Don Poldermans
Nowadays more and more clinical guidelines are developed. Clinical guidelines aim to assist practitioner and patient decision making about appropriate care for specific clinical conditions. Furthermore, guidelines can play a crucial role in the quality cycle form guidelines to clinical practice. However, this does not necessarily mean that these guidelines are actually implemented and the ultimately goal, improved patient outcome, is achieved. Care gaps exist between guidelines and daily clinical practice in perioperative care...
June 2011: Best Practice & Research. Clinical Gastroenterology
Erik J Bakker, Niels J C Ravensbergen, Don Poldermans
PURPOSE OF REVIEW: Cardiac complications after noncardiac surgery cause significant morbidity and mortality. This review will discuss recent developments in risk stratification, monitoring, and risk reduction strategies. RECENT FINDINGS: The addition of biomarkers for ischemia, left ventricular function, and atherosclerosis to classic cardiac risk factors improves the prediction of both short-term and long-term outcome after noncardiac surgery. Intraoperative monitoring, using continuous 12-lead ECG assessment and transesophageal echocardiography, may timely identify treatable myocardial ischemia and arrhythmias...
October 2011: Current Opinion in Critical Care
Simon J Howell, Sanne E Hoeks, Don Poldermans, Robert M West, Stephen B Wheatcroft
No abstract text is available yet for this article.
June 2011: European Journal of Anaesthesiology
Michiel T Voûte, Johanna M Hendriks, Jorinde H H van Laanen, Peter M T Pattynama, Bart E Muhs, Don Poldermans, Hence J M Verhagen
PURPOSE: To assess the differences in radial force of carotid stents and whether the length of the lesion influences the measurements. MATERIALS AND METHODS: Different models of tapered stents of similar size (length, 30 mm) were used. The tapered nitinol Acculink, Protégé, and Cristallo Ideale carotid artery stents and the straight, braided Elgiloy carotid Wallstent were compared. A measurement device consisting of three film loops along the stent body connected to aluminium rods with copper strain gauges was developed...
May 2011: Journal of Vascular and Interventional Radiology: JVIR
Inge I de Liefde, Hence J M Verhagen, Robert Jan Stolker, Ron T van Domburg, Don Poldermans
BACKGROUND: Exercise test parameters (exercise ankle brachial index (ABI), walking distance and blood pressure response) separately are associated with long-term outcome in patients with known or suspected peripheral arterial disease (PAD). However, the clinical value of the combination of these parameters together is unknown. METHODS: 2165 patients performed a treadmill exercise test to diagnose or to evaluate their PAD. Resting ABI, exercise ABI, abnormal blood pressure response (hypotensive and hypertensive) and walking distance (impairment <150 m) were measured...
April 2012: European Journal of Preventive Cardiology
Arnold C T Ng, Victoria Delgado, Matteo Bertini, Marie Louisa Antoni, Rutger J van Bommel, Eva P M van Rijnsoever, Frank van der Kley, See Hooi Ewe, Tomasz Witkowski, Dominique Auger, Gaetano Nucifora, Joanne D Schuijf, Don Poldermans, Dominic Y Leung, Martin J Schalij, Jeroen J Bax
AIMS: To identify changes in multidirectional strain and strain rate (SR) in patients with aortic stenosis (AS). METHODS AND RESULTS: A total of 420 patients (age 66.1 ± 14.5 years, 60.7% men) with aortic sclerosis, mild, moderate, and severe AS with preserved left ventricular (LV) ejection fraction [(EF), ≥50%] were included. Multidirectional strain and SR imaging were performed by two-dimensional speckle tracking. Patients were more likely to be older (P < 0...
June 2011: European Heart Journal
Daniel G Hackam, Kaveh G Shojania, J David Spence, David A Alter, Rob S Beanlands, George K Dresser, Aashish Goela, Alun H Davies, Luigi P Badano, Don Poldermans, Eric Boersma, Valentine Y Njike
BACKGROUND: Despite extensive use in practice, the impact of noninvasive cardiovascular imaging in primary prevention remains unclear. METHODS: We searched for randomized trials that compared imaging with usual care and reported any of the following outcomes in a primary prevention setting: medication prescribing, lifestyle modification (including diet, exercise, or smoking cessation), angiography, or revascularization. RESULTS: Seven trials were included...
June 13, 2011: Archives of Internal Medicine
Inge I de Liefde, Jan Klein, Jeroen J Bax, Hence J M Verhagen, Ron T van Domburg, Don Poldermans
BACKGROUND: The clinical value of exercise ankle brachial index (ABI) is still unclear, especially in patients with normal resting ABI. METHOD: 2164 patients performed a single-stage treadmill exercise test to diagnose or evaluate PAD. The population was divided into two groups: a normal resting ABI (resting ABI≥0.90) and PAD (resting ABI<0.90). Patients with a normal resting ABI were divided into 4 exercise ABI groups: exercise ABI<0.90, 0.90-0.99, 1.00-1...
June 2011: Atherosclerosis
Inge I de Liefde, Gijs M J M Welten, Hence J M Verhagen, Ron T van Domburg, Robert Jan Stolker, Don Poldermans
OBJECTIVE: Earlier studies have shown that hypertensive or hypotensive blood pressure (BP) response during a preoperative treadmill exercise test in patients with peripheral arterial disease is associated with a two-fold increased risk of cardiovascular events and mortality. However, it is unknown if these patients also experience an increased perioperative complication risk at major vascular surgery. METHODS: In total 665 consecutive patients with peripheral arterial disease underwent elective major vascular surgery (carotid endarterectomy, abdominal aorta repair, or lower extremity revascularization)...
June 2011: Coronary Artery Disease
Miriam Shanks, Victoria Delgado, Arnold C T Ng, Dominique Auger, Eline A Q Mooyaart, Matteo Bertini, Nina Ajmone Marsan, Rutger J van Bommel, Eduard R Holman, Don Poldermans, Martin J Schalij, Jeroen J Bax
BACKGROUND: Lack of response to cardiac resynchronization therapy (CRT) ranges between 30% to 40% of heart failure (HF) patients. The present study aimed to evaluate the clinical and echocardiographic determinants of nonresponse to CRT. METHODS: A total of 581 patients (66.4 ± 10.0 years, 77.9% male) with advanced HF scheduled for CRT implantation were included. Clinical and echocardiographic evaluations were performed at baseline and 6 months of follow-up. Nonresponse was defined as no improvement in the New York Heart Association functional class, death from worsening HF or heart transplantation, and <15% reduction in left ventricular (LV) end-systolic volume...
March 2011: American Heart Journal
Jan-Peter van Kuijk, Willem-Jan Flu, Tabita M Valentijn, Michel Chonchol, Michiel T Voûte, Ruud J Kuiper, Hence J M Verhagen, Jeroen J Bax, Don Poldermans
BACKGROUND: Both preoperative left ventricular dysfunction (LVD) and acute kidney injury (AKI) in the postoperative period are independently associated with mortality. We evaluated the prevalence and prognostic implications of AKI in a cohort of vascular surgery patients. METHODS: Before vascular surgery, 1,158 patients were screened for LVD. Development of AKI, defined by RIFLE classification, was detected by serial serum creatinine measurements at days 1 to 3 after surgery...
November 2011: Journal of Nephrology
Patrice P Cacoub, Uwe Zeymer, Tobias Limbourg, Iris Baumgartner, Don Poldermans, Joachim Röther, Deepak L Bhatt, Philippe Gabriel Steg et al.
OBJECTIVES: To examine the impact of cardiovascular risk factor control on 3-year cardiovascular event rates in patients with stable symptomatic atherothrombotic disease in Europe. METHODS: The REduction of Atherothrombosis for Continued Health (REACH) Registry recruited patients aged ≥45 years with established atherothrombotic disease or three or more risk factors, of whom 20 588 symptomatic patients from 18 European countries were analysed in this study at baseline and 12, 24 and 36 months...
April 2011: Heart: Official Journal of the British Cardiac Society
Michael Levy, Diane Heels-Ansdell, Rajesh Hiralal, Mohit Bhandari, Gordon Guyatt, Salim Yusuf, Deborah Cook, Juan Carlos Villar, Matthew McQueen, Edward McFalls, Miodrag Filipovic, Holger Schünemann, John Sear, Pierre Foex, Wendy Lim, Giora Landesberg, Gilles Godet, Don Poldermans, Francesca Bursi, Miklos D Kertai, Neera Bhatnagar, P J Devereaux
BACKGROUND: There is uncertainty regarding the prognostic value of troponin and creatine kinase muscle and brain isoenzyme measurements after noncardiac surgery. METHODS: The current study undertook a systematic review and meta-analysis. The study used six search strategies and included noncardiac surgery studies that provided data from a multivariable analysis assessing whether a postoperative troponin or creatine kinase muscle and brain isoenzyme measurement was an independent predictor of mortality or a major cardiovascular event...
April 2011: Anesthesiology
Niels J C Ravensbergen, Michiel T Voute, Don Poldermans
INTRODUCTION: In the perioperative setting, there is still a high incidence of adverse cardiac events due to sudden coronary plaque rupture or oxygen supply-demand imbalance. β-Blockers play an important role in preventing these cardiac events. Discussion, however, remains on the side effects accompanying this therapy. AREAS COVERED: The evidence for perioperative use of β-blockers is summarized in this review in terms of risk reduction, perioperative safety and current clinical use...
July 2011: Expert Opinion on Drug Safety
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