keyword
https://read.qxmd.com/read/38388305/respiratory-dysfunction-in-persistent-somatic-symptoms-a-systematic-review-of-observational-studies
#21
JOURNAL ARTICLE
Saya Niwa, Karolina Fila-Pawłowska, Omer Van den Bergh, Joanna Rymaszewska
OBJECTIVE: This systematic review aims to analyze the existing literature investigating respiratory functioning in people with Persistent Somatic Symptoms (PSS) compared to healthy controls, to identify patterns of respiratory disturbances by symptom or syndrome, and describe any respiratory outcomes consistent across diagnoses. METHODS: A systematic review following PRISMA guidelines was conducted. A comprehensive search was carried out across five databases (PubMed (NCBI), PsycArticles (Ovid), Web of Science (Core Collection), Embase, and Scopus) using two customised search strings for persistent somatic symptoms and objective respiratory parameters...
February 12, 2024: Journal of Psychosomatic Research
https://read.qxmd.com/read/38385182/assessing-the-pulmonary-vascular-responsiveness-to-oxygen-with-proton-mri
#22
JOURNAL ARTICLE
Abhilash S Kizhakke Puliyakote, Vincent Tedjasaputra, Gregory M Petersen, Rui Carlos Sá, Susan R Hopkins
Ventilation-perfusion matching occurs passively and is also actively regulated through hypoxic pulmonary vasoconstriction (HPV). The extent of HPV activity in humans, particularly normal subjects is uncertain. Current evaluation of HPV assesses changes in ventilation-perfusion relationships/pulmonary vascular resistance with hypoxia and are invasive, or unsuitable for patients because of safety concerns. We used a non-invasive imaging-based approach to quantify the pulmonary vascular response to oxygen as a metric of HPV by measuring perfusion changes between breathing 21% and 30%O2 using arterial spin labeling (ASL) MRI...
February 22, 2024: Journal of Applied Physiology
https://read.qxmd.com/read/38383357/comparison-of-high-flow-nasal-cannula-oxygenation-and-non-invasive-ventilation-for-postoperative-pediatric-cardiac-surgery-a-meta-analysis
#23
JOURNAL ARTICLE
Si-Jia Zhou, Xiu-Hua Chen, Ying-Ying Liu, Qiang Chen, Yi-Rong Zheng, Qi-Liang Zhang
OBJECTIVE: To evaluate the efficacy of high-flow nasal cannula oxygenation (HFNC) versus non-invasive ventilation (NIV) in pediatric patients post-congenital heart surgery (CHS) through a meta-analysis. METHODS: A comprehensive literature search was conducted across the Chinese biomedical literature database, Vip database, CNKI, Wanfang, PubMed, Embase, Cochrane Library, and Web of Science until December 20, 2022. We selected RCTs or cohort studies that met inclusion criteria for a meta-analysis using RevMan 5...
February 21, 2024: BMC Pulmonary Medicine
https://read.qxmd.com/read/38381730/lung-impedance-changes-during-awake-prone-positioning-in-covid-19-a-non-randomized-cross-over-study
#24
JOURNAL ARTICLE
Jacob Rosén, Peter Frykholm, Malin Jonsson Fagerlund, Mariangela Pellegrini, Francesca Campoccia Jalde, Erik von Oelreich, Diddi Fors
BACKGROUND: The effects of awake prone positioning (APP) on respiratory mechanics in patients with COVID-19 are not well characterized. The aim of this study was to investigate changes of global and regional lung volumes during APP compared with the supine position using electrical lung impedance tomography (EIT) in patients with hypoxemic respiratory failure due to COVID-19. MATERIALS AND METHODS: This exploratory non-randomized cross-over study was conducted at two university hospitals in Sweden between January and May 2021...
2024: PloS One
https://read.qxmd.com/read/38380460/-indocyanine-green-fluorescence-in-thoracoscopic-segmentectomy-indications-and-benefits
#25
JOURNAL ARTICLE
V G Pischik, A I Kovalenko, A V Molkova, E Yu Yuryev, E I Zinchenko, O A Maslak
OBJECTIVE: To determine the role of ICG fluorescence in segmentectomies. MATERIAL AND METHODS: One surgical team performed 178 thoracoscopic anatomical segmentectomies in two hospitals between 2017 and 2023. Of these, 93 (52.2%) patients underwent ICG fluorescence perfusion tests. This study was retrospective and consecutive. Intraoperative and early postoperative results were analyzed. Patients were divided into 3 equal periods. Ventilation and perfusion methods were used to navigate the intersegmental planes in the first period...
2024: Khirurgiia
https://read.qxmd.com/read/38380108/anaesthesia-management-for-neurosurgery-in-a-patient-with-congenital-lung-agenesis
#26
Sangeetha Selvaraj, Yingmao Gn, Theodore G Wong, Shariq Ali Khan
Congenital lung agenesis is a rare congenital abnormality associated with an absence or under-development of either one or both lungs, and its presentation in adulthood is even rarer. We describe a 40-year-old female patient with a history of congenital agenesis of the right lung and a high-grade glioma in the frontal region of the brain presenting for craniotomy and excision of the tumor in an MRI suite. Lung protective strategies of ventilation were utilized intraoperatively. The remote location of the MRI suite made access to extra manpower support challenging...
February 2024: Curēus
https://read.qxmd.com/read/38378325/phase-resolved-functional-lung-preful-mri-to-quantify-ventilation-feasibility-and-physiological-relevance-in-severe-asthma
#27
JOURNAL ARTICLE
Yonni Friedlander, Samal Munidasa, Ashutosh Thakar, Nandhitha Ragunayakam, Carmen Venegas, Melanie Kjarsgaard, Brandon Zanette, Dante P I Capaldi, Giles Santyr, Parameswaran Nair, Sarah Svenningsen
RATIONALE AND OBJECTIVES: Emergent evidence in several respiratory diseases supports translational potential for Phase-Resolved Functional Lung (PREFUL) MRI to spatially quantify ventilation but its feasibility and physiological relevance have not been demonstrated in patients with asthma. This study compares PREFUL-derived ventilation defect percent (VDP) in severe asthma patients to healthy controls and measures its responsiveness to bronchodilator therapy and relation to established measures of airways disease...
February 19, 2024: Academic Radiology
https://read.qxmd.com/read/38374167/coexistence-of-a-fluid-responsive-state-and-venous-congestion-signals-in-critically-ill-patients-a-multicenter-observational-proof-of-concept-study
#28
MULTICENTER STUDY
Felipe Muñoz, Pablo Born, Mario Bruna, Rodrigo Ulloa, Cecilia González, Valerie Philp, Roberto Mondaca, Juan Pablo Blanco, Emilio Daniel Valenzuela, Jaime Retamal, Francisco Miralles, Pedro D Wendel-Garcia, Gustavo A Ospina-Tascón, Ricardo Castro, Philippe Rola, Jan Bakker, Glenn Hernández, Eduardo Kattan
BACKGROUND: Current recommendations support guiding fluid resuscitation through the assessment of fluid responsiveness. Recently, the concept of fluid tolerance and the prevention of venous congestion (VC) have emerged as relevant aspects to be considered to avoid potentially deleterious side effects of fluid resuscitation. However, there is paucity of data on the relationship of fluid responsiveness and VC. This study aims to compare the prevalence of venous congestion in fluid responsive and fluid unresponsive critically ill patients after intensive care (ICU) admission...
February 19, 2024: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38372517/-not-available
#29
JOURNAL ARTICLE
Pikabalo Tchetike, Damessane Lamboni, Sarakawabalo Assenouwe, Magnoudewa Poko, Ernest Ahounou, Amouki Serge Tresor Anate, Tarek Alassani, H Kolme Dissoba, Hamza Doles Sama, EssohanamTabana Mouzou
INTRODUCTION: Thoracic surgery is a specialty with specific anesthetic management requirements. This is a recent specialty in Togo, with a multi-skilled anesthetic team. AIM: To describe the anesthetic management and morbidity of thoracic surgery. METHODS: A descriptive, prospective and observational study was conducted on a cohort of patients who underwent a thoracic surgery between June 1 and August 31, 2022, at the national referral hospital in Lomé...
May 5, 2023: La Tunisie Médicale
https://read.qxmd.com/read/38371066/characteristics-and-outcomes-of-children-with-severe-acute-respiratory-syndrome-coronavirus-2-sars-cov-2-infection-admitted-to-a-quaternary-hospital-a-single-center-experience
#30
JOURNAL ARTICLE
Saleh S Alshehri, Bushra I Minhaji, Mohsina R Pasha, Dina Fouda, Jency Joseph, Nehad Ahmed
Objectives In the setting of the recent global pandemic, children infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus causing the coronavirus disease 2019 (COVID-19) presented to our hospital with a variety of symptoms ranging from mild to severe disease including multiorgan dysfunction. Our objective was to study the clinical profile, risk factors, complications, and outcomes in pediatric patients admitted to our center with SARS-CoV-2 infection. Methods This retrospective observational study was conducted at a large quaternary center in Riyadh between May 2020 and September 2021...
January 2024: Curēus
https://read.qxmd.com/read/38369849/pain-trajectories-after-bilateral-orthotopic-lung-transplantation-surgery-performed-via-a-clamshell-incision
#31
JOURNAL ARTICLE
Negmeldeen Mamoun, Morgan A Rosser, Michael Manning, Karthik Raghunathan, Sharon McCartney, Sachin Mehta, Krista Ingle, Brandi Bottiger
INTRODUCTION: The nature, intensity, and progression of acute pain after bilateral orthotopic lung transplantation (BOLT) performed via a clamshell incision has not been well investigated. We aimed to describe acute pain after clamshell incisions using pain trajectories for the study cohort, in addition to stratifying patients into separate pain trajectory groups and investigating their association with donor and recipient perioperative variables. METHODS: After obtaining IRB approval, we retrospectively included all patients ≥18 years old who underwent primary BOLT via clamshell incision at a single center between January 1, 2017, and June 30, 2022...
February 2024: Clinical Transplantation
https://read.qxmd.com/read/38368302/ultrasound-guided-versus-conventional-lung-recruitment-manoeuvres-in-thoracic-surgery-a-randomised-controlled-study
#32
JOURNAL ARTICLE
Lei Wu, Li Yang, Yanyan Yang, Xin Wu, Jun Zhang
Lung recruitment manoeuvres (RMs) during mechanical ventilation may reduce atelectasis, however, the optimal recruitment strategy for patients undergoing thoracic surgery remains unknown. Our study was designed to investigate whether ultrasound-guided lung RMs is superior to conventional RMs in reducing perioperative atelectasis during thoracic surgery with one-lung ventilation. We conducted a randomised controlled clinical trial from August 2022 to September 2022. Sixty patients scheduled for video-assisted thoracoscopic surgery (VATS) under general anaesthesia were enrolled...
February 17, 2024: Journal of Clinical Monitoring and Computing
https://read.qxmd.com/read/38364876/-technical-aspects-and-innovations-in-non-invasive-and-invasive-ventilation
#33
JOURNAL ARTICLE
Dominic Dellweg, Philipp M Lepper
Non-invasive and invasive ventilation have become essential for therapy in acute and chronic respiratory failure. More than one-third of patients in intensive care units receive invasive ventilation, and the number of ventilated patients in out-of-hospital care is also steadily increasing. While normalization of blood gases was considered the most significant goal in past decades, and the idea that mechanical ventilation also poses dangers played little role, the dominant thought at present is the application of ventilation from the most protective point of view possible...
February 2024: Pneumologie
https://read.qxmd.com/read/38363783/development-of-the-terminal-air-spaces-in-the-gray-short-tailed-opossum-monodelphis-domestica-3d-reconstruction-by-microcomputed-tomography
#34
JOURNAL ARTICLE
Kirsten Ferner
Marsupials are born with structurally immature lungs when compared to eutherian mammals. The gray short-tailed opossum (Monodelphis domestica) is born at the late canalicular stage of lung development. Despite the high degree of immaturity, the lung is functioning as respiratory organ, however supported by the skin for gas exchange during the first postnatal days. Consequently, the majority of lung development takes place in ventilated functioning state during the postnatal period. Microcomputed tomography (μCT) was used to three-dimensionally reconstruct the terminal air spaces in order to reveal the timeline of lung morphogenesis...
2024: PloS One
https://read.qxmd.com/read/38362833/short-term-effects-of-positive-expiratory-pressure-mask-on-ventilation-inhomogeneity-in-children-with-cystic-fibrosis-a-randomized-sham-controlled-crossover-study
#35
JOURNAL ARTICLE
Simone Gambazza, Alessandra Mariani, Riccardo Guarise, Beatrice Ferrari, Federica Carta, Anna Brivio, Sofia Bizzarri, Chiara Castellani, Carla Colombo, Dario Laquintana
BACKGROUND: Can physiotherapy with a positive expiratory pressure (PEP) mask improve peripheral ventilation inhomogeneity, a typical feature of children with cystic fibrosis (cwCF)? To answer this question, we used the nitrogen multiple-breath washout (N2 MBW) test to measure diffusion-convection-dependent inhomogeneity arising within the intracinar compartment (Sacin *VT). METHODS: For this randomized, sham-controlled crossover trial, two N2 MBW tests were performed near the hospital discharge date: one before and the other after PEP mask therapy (1 min of breathing through a flow-dependent PEP device attached to a face mask, followed by three huffs and one cough repeated 10 times) by either a standard (10-15 cmH2 0) or a sham (<5 cmH2 0) procedure on two consecutive mornings...
February 16, 2024: Pediatric Pulmonology
https://read.qxmd.com/read/38360855/cyclosporine-a-in-hospitalized-covid-19-pneumonia-patients-to-prevent-the-development-of-interstitial-lung-disease-a-pilot-randomized-clinical-trial
#36
JOURNAL ARTICLE
Tatiana Cobo-Ibáñez, Gemma Mora Ortega, Carlos Sánchez-Piedra, Gonzalo Serralta-San Martín, Israel J Thuissard-Vasallo, Vanesa Lores Gutiérrez, Llanos Soler Rangel, Cristina García Yubero, Ana Esteban-Vázquez, Elena López-Aspiroz, Cristina Andreu Vázquez, Inmaculada Toboso, Blanca María Martínez Alonso de Armiño, Rocío Alejandra Olivares Alviso, Rocío Calderón Nieto, Cecilia Yañez, Marlín Alejandra Zakhour González, Tatiana Sainz Sánchez, Silvia Arroyo de la Torre, Nazaret Del Amo Del Arco, Jorge Francisco Gómez-Cerezo, Teresa Ramírez Prieto, Alicia Martínez Hernández, Santiago Muñoz-Fernández
Post-COVID-19 interstitial lung disease (ILD) is a new entity that frequently causes pulmonary fibrosis and can become chronic. We performed a single-center parallel-group open-label pilot randomized clinical trial to investigate the efficacy and safety of cyclosporine A (CsA) in the development of ILD in the medium term among patients hospitalized with COVID-19 pneumonia. Patients were randomized 1:1 to receive CsA plus standard of care or standard of care alone. The primary composite outcome was the percentage of patients without ILD 3 months after diagnosis of pneumonia and not requiring invasive mechanical ventilation (IMV) (response without requiring IMV)...
February 15, 2024: Scientific Reports
https://read.qxmd.com/read/38360346/impact-of-early-tracheostomy-following-lung-transplantation-a-national-analysis
#37
JOURNAL ARTICLE
Nicole Charland, Nikhil Chervu, Saad Mallick, Nguyen Le, Joanna Curry, Amulya Vadlakonda, Peyman Benharash
BACKGROUND: Prolonged mechanical ventilation is common among lung transplant recipients, affecting nearly one-third of patients. Tracheostomy has been shown as a beneficial alternative to endotracheal intubation, but delays in tracheostomy tube placement persist. To date, no large-scale study has investigated the effect of tracheostomy timing on posttransplant outcomes. METHODS: All adults receiving tracheostomy following primary, isolated lung transplantation were identified in the 2016-2020 Nationwide Readmissions Database...
February 13, 2024: Annals of Thoracic Surgery
https://read.qxmd.com/read/38360161/extended-ischemic-time-15-hours-using-controlled-hypothermic-storage-in-lung-transplantation-a-multicenter-experience
#38
JOURNAL ARTICLE
Rene Novysedlak, An-Lies Provoost, Nathaniel B Langer, Jan Van Slambrouck, Annalisa Barbarossa, Ismail Cenik, Dirk Van Raemdonck, Robin Vos, Bart M Vanaudenaerde, Seyed Alireza Rabi, Brian C Keller, Monika Svorcova, Zuzana Ozaniak Strizova, Jiri Vachtenheim, Robert Lischke, Laurens J Ceulemans
Static ice storage has long been the standard-of-care for lung preservation, although freezing injury limits ischemic time (IT). Controlled hypothermic storage (CHS) at elevated temperature could safely extend IT. This retrospective analysis assesses feasibility and safety of CHS with IT>15h. Three lung transplant (LuTx) centers (April-October 2023) included demographics, storage details, IT and short-term outcome from 13 LuTx recipients (8 male, 59 years old). Donor lungs were preserved in a portable CHS-device at 7(5-9...
February 13, 2024: Journal of Heart and Lung Transplantation
https://read.qxmd.com/read/38347503/successful-application-of-airway-pressure-release-ventilation-in-a-child-with-severe-acute-respiratory-distress-syndrome-induced-by-trauma-a-case-report
#39
JOURNAL ARTICLE
Jing Su, Xin Tie, Yao Chen, Tongjuan Zou, Wanhong Yin
BACKGROUND: Trauma has been identified as one of the risk factors for acute respiratory distress syndrome. Respiratory support can be further complicated by comorbidities of trauma such as primary or secondary lung injury. Conventional ventilation strategies may not be suitable for all trauma-related acute respiratory distress syndrome. Airway pressure release ventilation has emerged as a potential rescue method for patients with acute respiratory distress syndrome and hypoxemia refractory to conventional mechanical ventilation...
February 12, 2024: BMC Pulmonary Medicine
https://read.qxmd.com/read/38337565/ventilation-management-in-a-patient-with-ventilation-perfusion-mismatch-in-the-early-phase-of-lung-injury-and-during-the-recovery
#40
Ana Cicvarić, Josipa Glavaš Tahtler, Tajana Turk, Sanda Škrinjarić-Cincar, Despoina Koulenti, Nenad Nešković, Mia Edl, Slavica Kvolik
Chest trauma is one of the most serious and difficult injuries, with various complications that can lead to ventilation-perfusion (V/Q) mismatch and systemic hypoxia. We are presenting a case of a 53-year-old male with no chronic therapy who was admitted to the Intensive Care Unit due to severe respiratory failure after chest trauma. He developed a right-sided pneumothorax, and then a thoracic drain was placed. On admission, the patient was hemodynamically unstable and tachypneic. He was intubated and mechanically ventilated, febrile (38...
February 2, 2024: Journal of Clinical Medicine
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