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https://www.readbyqxmd.com/read/29318498/collection-and-preservation-of-urinary-proteins-using-a-fluff-pulp-diaper
#1
Weiwei Qin, Zhenhuan Du, Youhe Gao
Change is the most fundamental property of a biomarker. In contrast to the blood, which is under homeostatic controls, urine reflects changes in the body earlier and is more sensitive, thus making it a better biomarker source. Moreover, drawing blood from infants and toddlers is difficult and not tolerated well. For patients limited by language, communicating their chief complaint is difficult. Thus, monitoring biomarkers in urine can provide valuable clues for the diagnosis of diseases, especially pediatric diseases...
January 4, 2018: Science China. Life Sciences
https://www.readbyqxmd.com/read/29283178/implementation-of-an-evidenced-based-parenting-program-in-a-community-mental-health-setting
#2
Monica Roosa Ordway, Thomas J Mcmahon, Lourdes De Las Heras Kuhn, Nancy E Suchman
The process of mental health intervention implementation with vulnerable populations is not well-described in the literature. The authors worked as a community-partnered team to adapt and pilot an empirically supported intervention program for mothers of infants and toddlers in an outpatient mental health clinic that primarily serves a low-income community. We used qualitative ethnographic methods to document the adaption of an evidence-based intervention, Mothering from the Inside Out, and the pilot implementation in a community mental health clinic...
December 28, 2017: Infant Mental Health Journal
https://www.readbyqxmd.com/read/29279889/association-of-folic-acid-supplementation-during-pregnancy-with-the-risk-of-autistic-traits-in-children-exposed-to-antiepileptic-drugs-in-utero
#3
Marte Bjørk, Bettina Riedel, Olav Spigset, Gyri Veiby, Eivind Kolstad, Anne Kjersti Daltveit, Nils Erik Gilhus
Importance: Strategies to prevent autism in children exposed to antiepileptic drugs (AEDs) during pregnancy are important. Objective: To explore whether folic acid supplementation and folate status in pregnancy are associated with reduced risk of autistic traits owing to in utero AED exposure. Design, Setting, and Participants: The population-based, prospective Norwegian Mother and Child Cohort Study approached Norwegian-speaking women attending routine ultrasonographic examinations from June 1999 through December 31, 2008 (163 844 of 277 702 women refused)...
December 26, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29262472/-structural-change-of-the-corpus-callosum-fibers-in-toddlers-with-autism-spectrum-disorder-two-year-follow-up
#4
C Chang, N N Qiu, T Xiao, X Xiao, K K Chu, Y Li, Q R Wu, H Fang, X Y Ke
Objective: To conduct a follow-up investigation of structural changes of the corpus callosum fibers of toddlers (2 to 5 years of age) with autism spectrum disorder(ASD) and to explore the associations with clinical symptoms. Method: In this prospective randomized controlled study, ASD children who were diagnosed in the Child Mental Health Research Center, Nanjing Brain Hospital Affiliated to Nanjing Medical University from May 2011 to November 2012 were included in the ASD group, and developmentally delayed children were included in the control group (DD group)...
December 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29218767/maternal-communicative-behaviours-and-interaction-quality-as-predictors-of-language-development-findings-from-a-community-based-study-of-slow-to-talk-toddlers
#5
Laura J Conway, Penny A Levickis, Jodie Smith, Fiona Mensah, Melissa Wake, Sheena Reilly
BACKGROUND: Identifying risk and protective factors for language development informs interventions for children with developmental language disorder (DLD). Maternal responsive and intrusive communicative behaviours are associated with language development. Mother-child interaction quality may influence how children use these behaviours in language learning. AIMS: To identify (1) communicative behaviours and interaction quality associated with language outcomes; (2) whether the association between a maternal intrusive behaviour (directive) and child language scores changed alongside a maternal responsive behaviour (expansion); and (3) whether interaction quality modified these associations...
December 7, 2017: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/29198963/prenatal-phthalate-exposure-and-language-development-in-toddlers-from-the-odense-child-cohort
#6
Trine Staak Olesen, Dorthe Bleses, Helle Raun Andersen, Philippe Grandjean, Hanne Frederiksen, Fabio Trecca, Niels Bilenberg, Henriette Boye Kyhl, Louise Dalsager, Inge Kjær Jensen, Anna-Maria Andersson, Tina Kold Jensen
BACKGROUND: Phthalates are a group of chemicals found in a variety of consumer products. They have anti-androgenic properties and human studies have reported associations between prenatal phthalate exposure and neuropsychological development in the offspring despite different cognitive tests, different ages and varying timing of exposure. OBJECTIVES: To investigate the association between prenatal phthalate exposure and language development in children aged 20-36months...
November 30, 2017: Neurotoxicology and Teratology
https://www.readbyqxmd.com/read/29181689/do-parents-and-clinicians-agree-on-ratings-of-autism-related-behaviors-at-12-months-of-age-a-study-of-infants-at-high-and-low-risk-for-asd
#7
Suzanne L Macari, Grace C Wu, Kelly K Powell, Scuddy Fontenelle, Deanna M Macris, Katarzyna Chawarska
Given the emphasis on early screening for ASD, it is crucial to examine the concordance between parent report and clinician observation of autism-related behaviors. Similar items were compared from the First Year Inventory (Baranek et al. First-Year Inventory (FYI) 2.0. University of North Carolina, Chapel Hill, 2003), a parent screener for ASD, and the ADOS-2 Toddler Module (Lord et al. 2013), a standardized ASD diagnostic tool. Measures were administered concurrently to 12-month-olds at high and low risk for ASD...
November 27, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29173715/interprofessional-collaborative-practice-in-early-intervention
#8
REVIEW
Kathy L Coufal, Juliann J Woods
Professionals in pediatric practice encounter infants and toddlers with developmental delays, disabilities, or complex chronic health conditions eligible for Part C early intervention (EI) services. The most frequently identified concern by families is communication emphasizing the importance of the role of the speech language pathologist (SLP). This article provides a conceptual framework for SLP services in early intervention, based on the principles of interprofessional collaboration. The history of collaboration, EI, and the role of SLPs as members of the EI team are summarized...
February 2018: Pediatric Clinics of North America
https://www.readbyqxmd.com/read/29168087/mediating-parent-learning-to-promote-social-communication-for-toddlers-with-autism-effects-from-a-randomized-controlled-trial
#9
Hannah H Schertz, Samuel L Odom, Kathleen M Baggett, John H Sideris
A randomized controlled trial was conducted to evaluate effects of the Joint Attention Mediated Learning (JAML) intervention. Toddlers with autism spectrum disorders (ASD) aged 16-30 months (n = 144) were randomized to intervention and community control conditions. Parents, who participated in 32 weekly home-based sessions, followed a mediated learning process to target preverbal social communication outcomes (social visual synchrony, reciprocity, and responding and initiating forms of joint attention) throughout daily interactions...
November 22, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29162136/no-long-term-effect-of-a-2-days-intervention-on-how-to-prepare-homemade-food-on-toddlers-skepticism-for-new-food-and-intake-of-fruits-and-vegetables-and-sweet-beverages-a-randomized-controlled-trial
#10
C Beinert, S Hernes, M Haugen, N C Øverby
OBJECTIVE: Optimal nutrition from early age reduces the risk of developing non-communicable diseases later in life. The aim of this study was to examine the long-term effect on toddlers' fruit and vegetable intake and sweet beverages, and skepticism for new food, of a 2-days' intervention on how to prepare homemade food for toddlers. RESULTS: The effect of the cooking intervention was evaluated by a randomized, controlled trial where 110 parents of 4-6 months old infants were included...
November 21, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29158913/an-implementation-effectiveness-hybrid-trial-of-video-based-family-therapy-for-peripartum-depression-in-home-visited-mothers-a-protocol-for-a-pilot-trial
#11
Fallon Cluxton-Keller, Craig L Donnelly, Melony Williams, Jennifer Buteau, Patricia Stolte, Maggie Monroe-Cassel, Martha L Bruce
Background: The Federal Maternal, Infant, and Early Childhood Home Visiting (HV) Program serves over 100,000 vulnerable families at risk for child abuse in the USA and aims to improve many outcomes, including maternal mental health (HRSA's Federal Home Visiting Program: partnering with parents to help children succeed, 2017). Most clients are insured by Medicaid, and about 40% are adolescent mothers (pregnant and post-delivery) (The mother and infant home visiting program evaluation: early findings on the Maternal, Infant, and Early Childhood Home Visiting Program, 2015)...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29158765/usefulness-of-the-korean-developmental-screening-test-for-infants-and-children-for-the-evaluation-of-developmental-delay-in-korean-infants-and-children-a-single-center-study
#12
Chung-Hyuk Yim, Gun-Ha Kim, Baik-Lin Eun
Purpose: To evaluate the usefulness of the Korean Developmental Screening Test (K-DST) for infants and children for developmental delay assessment. Methods: This study was based on retrospective studies of the results of the K-DST, Preschool Receptive-Expressive Language Scale (PRES), Sequenced Language Scale for Infants (SELSI), Childhood Autism Rating Scale (CARS), Modified Checklist for Autism in Toddlers (M-CHAT), electroencephalography, magnetic resonance imaging, and extensive tests conducted in 209 of 1,403 patients, of whom 758 underwent the K-DST at the Korea University Guro Hospital between January 2015 and December 2016 and 645 were referred from local clinics between January 2015 and June 2016...
October 2017: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/29151556/-an-integrative-review-of-home-care-service-for-pregnant-women-mothers-infants-and-toddlers-in-vulnerable-group
#13
REVIEW
Dasom Kim, Insook Lee
PURPOSE: This study was intended to integrate the evidence of home care service intervention for mothers and children in vulnerable groups through an integrative literature review. METHODS: We searched the MEDLINE (PubMED), EMBASE, Cochrane Central Register of Controlled Trials, CINAHL, DBpia databases. The quality of the articles was assessed by one doctoral researcher and verified by one professor of community health nursing who had participated in the systematic review of literature...
October 2017: Journal of Korean Academy of Nursing
https://www.readbyqxmd.com/read/29148287/does-the-brief-observation-of-social-communication-change-help-moving-forward-in-measuring-change-in-early-autism-intervention-studies
#14
Mirjam Kj Pijl, Nanda Nj Rommelse, Monica Hendriks, Manon Wp De Korte, Jan K Buitelaar, Iris J Oosterling
The field of early autism research is in dire need of outcome measures that adequately reflect subtle changes in core autistic behaviors. This article compares the ability of a newly developed measure, the Brief Observation of Social Communication Change (BOSCC), and the Autism Diagnostic Observation Schedule (ADOS) to detect changes in core symptoms of autism in 44 toddlers. The results provide encouraging evidence for the Brief Observation of Social Communication Change as a candidate outcome measure, as reflected in sufficient inter- and intra-rater reliability, independency from other child characteristics, and sensitivity to capture change...
December 1, 2016: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/29056402/do-fathers-home-reading-practices-at-age-2-predict-child-language-and-literacy-at-age-4
#15
Jon Quach, Anna Sarkadi, Natasha Napiza, Melissa Wake, Amy Loughman, Sharon Goldfeld
BACKGROUND: Maternal shared reading practices predict emergent literacy, but fathers' contributions are less certain. We examined whether fathers' shared home reading activities at 2 years (1) predict language and emergent literacy at age 4 years, when controlling for maternal contributions; and (2) differentially benefit these outcomes in disadvantaged children. METHODS: Design: Two-parent families recruited from 5 relatively disadvantaged communities for the universal Let's Read literacy promotion population-based trial (ISRCTN 04602902) in Melbourne, Australia...
October 19, 2017: Academic Pediatrics
https://www.readbyqxmd.com/read/29052014/predictive-validity-of-a-service-setting-based-measure-to-identify-infancy-mental-health-problems-a-population-based-cohort-study
#16
Janni Ammitzbøll, Lau Caspar Thygesen, Bjørn E Holstein, Anette Andersen, Anne Mette Skovgaard
Measures to identify infancy mental health problems are essential to guide interventions and reduce the risk of developmental psychopathology in early years. We investigated a new service-setting-based measure the Copenhagen Infant Mental Health Screening (CIMHS) within the general child health surveillance by community health nurses (CHN). The study population of 2973 infants was assessed by CIMHS at age 9-10 months. A subsample of 416 children was examined at age 1½ years, using parent interviews including the Child Behavior Checklist (CBCL 1½-5), Check List of Autism and Toddlers (CHAT), Infant-Toddler Symptom Checklist (ITSCL), and the Bayley Scales of Infant and Toddler Development (BSID) and observations of behavior, communication, and interaction...
October 20, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29040615/exploring-cascading-effects-of-multimodal-communication-skills-in-infants-with-hearing-loss
#17
Megan Y Roberts, Lauren H Hampton
Infants and toddlers with hearing loss (HL) are at risk for developing communicative delays that can have a substantial lasting effect. Understanding child characteristics that may be targeted in early intervention is essential to maximizing communicative outcomes in children with HL. Among the most malleable predictors of communication skills include maternal responsivity, gestures, and vocalizations. The purpose of this study was to examine the relationship among maternal responsivity, prelinguistic communication skills and expressive vocabulary in children with HL...
October 13, 2017: Journal of Deaf Studies and Deaf Education
https://www.readbyqxmd.com/read/28992611/co-viewing-supports-toddlers-word-learning-from-contingent-and-noncontingent-video
#18
Gabrielle A Strouse, Georgene L Troseth, Katherine D O'Doherty, Megan M Saylor
Social cues are one way young children determine that a situation is pedagogical in nature-containing information to be learned and generalized. However, some social cues (e.g., contingent gaze and responsiveness) are missing from prerecorded video, a potential reason why toddlers' language learning from video can be inefficient compared with their learning directly from a person. This study explored two methods for supporting children's word learning from video by adding social-communicative cues. A sample of 88 30-month-olds began their participation with a video training phase...
February 2018: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/28964316/speech-processor-data-logging-helps-in-predicting-early-linguistic-outcomes-in-implanted-children
#19
Letizia Guerzoni, Domenico Cuda
OBJECTIVE: To analyse the value of listening-data logged in the speech processor on the prediction of the early auditory and linguistic skills in children who received a cochlear implant in their first 2 years of life. STUDY DESIGN: Prospective observational non-randomized study. METHODS: Ten children with profound congenital sensorineural hearing loss were included in the study. The mean age at CI activation was 16.9 months (SD ± 7.2; range 10-24)...
October 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28939027/simulating-interaction-using-gaze-contingent-eye-tracking-to-measure-the-reward-value-of-social-signals-in-toddlers-with-and-without-autism
#20
Angelina Vernetti, Atsushi Senju, Tony Charman, Mark H Johnson, Teodora Gliga
Several accounts have been proposed to explain difficulties with social interaction in autism spectrum disorder (ASD), amongst which atypical social orienting, decreased social motivation or difficulties with understanding the regularities driving social interaction. This study uses gaze-contingent eye-tracking to tease apart these accounts by measuring reward related behaviours in response to different social videos. Toddlers at high or low familial risk for ASD took part in this study at age 2 and were categorised at age 3 as low risk controls (LR), high-risk with no ASD diagnosis (HR-no ASD), or with a diagnosis of ASD (HR-ASD)...
August 12, 2017: Developmental Cognitive Neuroscience
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