keyword
MENU ▼
Read by QxMD icon Read
search

toxic hair

keyword
https://www.readbyqxmd.com/read/27913787/safety-assessment-of-polyquaternium-22-and-polyquarternium-39-as-used-in-cosmetics
#1
Wilbur Johnson, Bart Heldreth, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler, James G Marks, Ronald C Shank, Thomas J Slaga, Paul W Snyder, F Alan Andersen
Polyquaternium-22 and polyquaternium-39 are polymers that function as antistatic agents, film formers, and hair fixatives in cosmetic products. These ingredients are being used at concentrations up to 2% (polyquaternium-22, in a rinse-off product) and up to 3% (polyquaternium-39, in rinse-off and leave-on products). The unreacted monomer content of these ingredients was considered low and of no toxicological concern. Limited data showed no skin irritation/sensitization. Although these ingredients were nongenotoxic in bacterial assays, mammalian genotoxicity, carcinogenicity, and reproductive and developmental toxicity data were not available...
November 2016: International Journal of Toxicology
https://www.readbyqxmd.com/read/27908426/environmental-exposures-of-trace-elements-assessed-using-keratinized-matrices-from-patients-with-chronic-kidney-diseases-of-uncertain-etiology-ckdu-in-sri-lanka
#2
Saranga Diyabalanage, Sanjeewani Fonseka, D M S N B Dasanayake, Rohana Chandrajith
An alarming increase in chronic kidney disease with unknown etiology (CKDu) has recently been reported in several provinces in Sri Lanka and chronic exposures to toxic trace elements were blamed for the etiology of this disease. Keratinized matrices such as hair and nails were investigated to determine the possible link between CKDu and toxic element exposures. Elements Li, B, Al, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Sr, Mo, Cd, Ba, Hg and Pb of hair and nails of patients and age that matched healthy controls were determined with Inductively Coupled Plasma Mass Spectrometry (ICP-MS)...
January 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/27908406/trace-element-biomonitoring-in-hair-of-school-children-from-a-polluted-area-by-sector-field-inductively-coupled-plasma-mass-spectrometry
#3
Evgenii J Drobyshev, Nikolay D Solovyev, Natalya B Ivanenko, Maria Yu Kombarova, Alexander A Ganeev
In the current study, a biomonitoring of 18 hair trace elements (Al, As, Cd, Co, Cr, Cu, Fe, Hg, Mg, Mn, Ni, Pb, Se, V, Zn, Ca, Na and P) in school children from Leningradskaya Oblast' is reported. A case group, residing in a proximity to the toxic waste disposal grounds (Krasniy Bor), has been assessed vs. controls from a non-urban settlement Seltso. In total, 166 hair samples were analysed using double focusing sector field inductively coupled plasma mass spectrometry after microwave-assisted sample digestion with nitric acid...
January 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/27886267/in-vivo-characterization-of-hair-and-skin-derived-carbon-quantum-dots-with-high-quantum-yield-as-long-term-bioprobes-in-zebrafish
#4
Jing-Hui Zhang, Aping Niu, Jing Li, Jian-Wei Fu, Qun Xu, De-Sheng Pei
Carbon quantum dots (CDs) were widely investigated because of their tunable fluorescence properties and low toxicity. However, so far there have been no reports on in vivo functional studies of hair and skin derived CDs. Here, hair derived CDs (HCDs) and skin derived CDs (SCDs) were produced by using human hair and pig skin as precursors. The quantum yields (QYs) of HCDs and SCDs were quite high, compared to citric acid derived CDs (CCDs). HCDs and SCDs possess optimal photostability, hypotoxicity and biocompatibility in zebrafish, indicating that HCDs and SCDs possess the capacity of being used as fluorescence probes for in vivo biological imaging...
November 25, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27877128/safety-profiles-of-tripterygium-wilfordii-hook-f-a-systematic-review-and-meta-analysis
#5
Chi Zhang, Ping-Ping Sun, Hong-Tao Guo, Yan Liu, Jian Li, Xiao-Juan He, Ai-Ping Lu
Objective:Tripterygium wilfordii Hook F (TwHF) is a widely used and effective treatment for inflammatory diseases. There have been concerns about its toxicity but no adequate synthesis of the evidence for adverse events (AEs). We aimed to undertake a clinically informative, systematic safety profile of TwHF. Methods: We undertook a systematic review and meta-analysis of experimental studies and observational studies. We searched electronic databases and conference abstracts. Safety outcomes were rates of common AEs...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27873085/quantitative-analysis-of-supporting-cell-subtype-labeling-among-creer-lines-in-the-neonatal-mouse-cochlea
#6
Melissa M McGovern, Joseph Brancheck, Auston C Grant, Kaley A Graves, Brandon C Cox
Four CreER lines that are commonly used in the auditory field to label cochlear supporting cells (SCs) are expressed in multiple SC subtypes, with some lines also showing reporter expression in hair cells (HCs). We hypothesized that altering the tamoxifen dose would modify CreER expression and target subsets of SCs. We also used two different reporter lines, ROSA26 (tdTomato) and CAG-eGFP, to achieve the same goal. Our results confirm previous reports that Sox2 (CreERT2) and Fgfr3-iCreER (T2) are not only expressed in neonatal SCs but also in HCs...
November 21, 2016: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/27858271/pilot-study-on-the-internal-exposure-to-heavy-metals-of-informal-level-electronic-waste-workers-in-agbogbloshie-accra-ghana
#7
Jürgen Wittsiepe, Torsten Feldt, Holger Till, Gerd Burchard, Michael Wilhelm, Julius N Fobil
Informal-level electronic waste (e-waste)-processing activities are performed at hotspots in developing countries such as India, China, and Ghana. These activities increase the ambient burden of heavy metals and contribute to the toxic exposure of the general population. However, few data exist on the internal exposure of populations involved in these informal activities and in close contact with fumes from the direct combustion of electronic waste products in these countries. Therefore, in a cross-sectional study design, we analyzed blood, urine, and hair samples from 75 e-waste workers residing in and/or working on a large e-waste recycling site in Agbogbloshie, Accra, Ghana, and compared the results against those of 40 individuals living in a suburb of Accra without direct exposure to e-waste recycling activities...
November 17, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27847309/an-optimized-method-to-assess-ototoxic-effects-in-the-lateral-line-of-zebrafish-danio-rerio-embryos
#8
Daniel Stengel, Florian Zindler, Thomas Braunbeck
In order to clarify the suitability of the lateral line of zebrafish (Danio rerio) embryos as a model for the screening of ototoxic (neurotoxic) effects, existing neuromast assays were adapted, improved and validated with a series of chemicals known or unknown for their ototoxic potential (caffeine copper sulfate, dichlorvos, 2.4-dinitrotoluene, neomycin, 4-nonylphenol, perfluorooctanesulfonic acid). Present methods were improved by (1) the introduction of a 4-step scoring system, (2) the selection of neuromasts from both the anterior and posterior lateral line systems, (3) a combined DASPEI/DAPI staining applied after both a continuous and pulse exposure scenario, and (4) an additional screening for nuclear fragmentation...
November 12, 2016: Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP
https://www.readbyqxmd.com/read/27845215/formulation-and-comparative-in-vitro-evaluation-of-various-dexamethasone-loaded-ph-sensitive-polymeric-nanoparticles-intended-for-dermal-applications
#9
Fitsum Feleke Sahle, Christian Gerecke, Burkhard Kleuser, Roland Bodmeier
pH-sensitive nanoparticles have a great potential for dermal and transfollicular drug delivery. In this study, pH-sensitive, dexamethasone-loaded Eudragit(®) L 100, Eudragit(®) L 100-55, Eudragit(®) S 100, HPMCP-50, HPMCP-55 and cellulose acetate phthalate nanoparticles were prepared by nanoprecipitation and characterized. The pH-dependent swelling, erosion, dissolution and drug release kinetics were investigated in vitro using dynamic light scattering and Franz diffusion cells, respectively. Their toxicity potential was assessed by the ROS and MTT assays...
November 11, 2016: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/27828841/the-histocompatibility-research-of-hair-follicle-stem-cells-with-bladder-acellular-matrix
#10
Jia Li, Wenguang Wang, Jiuzhi Li, Mulati Rexiati, Henqing An, Feng Wang, Yujie Wang
BACKGROUND: Hair follicle stem cells (HFSCs) were reported to have multidirectional differentiation ability and could be differentiated into melanocytes, keratin cells, smooth muscle cells, and neurons. However, the functionality of HFSCs in bladder tissue regeneration is unknown. METHODS: This study was conducted to build HFSCs vs bladder acellular matrix (BAM) complexes (HFSCs-BAM complexes) in vitro and evaluated whether HFSCs have well biocompatibility with BAM...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27826822/an-updated-systematic-review-on-the-possible-effect-of-nonylphenol-on-male-fertility
#11
Zahra Noorimotlagh, Neemat Jaafarzadeh Haghighi, Mehdi Ahmadimoghadam, Fakher Rahim
Diverse industries like detergents, resins and polymers, hair dyes, intravaginal spermicides, and pesticides produce endocrine disruptor (ED)-containing wastewaters that have hazardous effects on the environment and public health. Nonylphenol (NP) is a chemical substance that consists of a phenolic group and an attached lipophilic linear nonyl chain. NP has weak estrogenic activity and affects estrogen receptor (ER), as well as induces male infertility via a negative impact on spermatogenesis and sperm quality...
November 8, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27794445/heavy-metals-in-the-volcanic-environment-and-thyroid-cancer
#12
R Vigneri, P Malandrino, F Gianì, M Russo, P Vigneri
In the last two decades thyroid cancer incidence has increased worldwide more than any other cancer. Overdiagnosis of subclinical microcarcinomas has certainly contributed to this increase but many evidences indicate that a true increase, possibly due to environmental factors, has also occurred. Thyroid cancer incidence is markedly increased in volcanic areas. Thus, the volcanic environment is a good model to investigate the possible factors favoring thyroid cancer. In the volcanic area of Mt. Etna in Sicily, as well as in other volcanic areas, a non-anthropogenic pollution with heavy metals has been documented, a consequence of gas, ash and lava emission...
October 26, 2016: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/27792983/feather-keratin-hydrogel-for-wound-repair-preparation-healing-effect-and-biocompatibility-evaluation
#13
Ju Wang, Shilei Hao, Tiantian Luo, Zhongjun Cheng, Wenfeng Li, Feiyan Gao, Tingwang Guo, Yuhua Gong, Bochu Wang
Keratins are highly attractive for wound healing due to their inherent bioactivity, biocompatibility and physical properties. However, nearly all wound healing studies have focused on human hair keratins, and the wound-repair effects and in vivo biocompatibilities of feather keratins are not clear. Feather keratins are derived from chicken feathers, which are considered to be the major waste in the poultry industry, and the quality of feather keratin is easier to control than that of human hair keratin due to human hair perming and colouring-dyeing...
October 22, 2016: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/27787949/pasireotide-prevents-nuclear-factor-of-activated-t-cells-nuclear-translocation-and-acts-as-a-protective-agent-in-aminoglycoside-induced-auditory-hair-cell-loss
#14
Daniel Bodmer, Adrijana Perkovic, Marijana Sekulic-Jablanovic, Matthew B Wright, Vesna Petkovic
Hearing impairment is a global health problem with a high socioeconomic impact. Damage to auditory hair cells (HCs) in the inner ear as a result of aging, disease, trauma, or toxicity, underlies the majority of cases of sensorineural hearing loss. Previously we demonstrated that the Ca(2+) -sensitive neuropeptide, somatostatin (SST), and an analog, octreotide, protect HCs from gentamicin-induced cell death in vitro. Aminoglycosides such as gentamicin trigger a calcium ion influx (Ca(2+) ) that activates pro-apoptotic signaling cascades in HCs...
October 27, 2016: Journal of Neurochemistry
https://www.readbyqxmd.com/read/27785740/analysis-of-hair-trace-elements-in-children-with-autism-spectrum-disorders-and-communication-disorders
#15
Anatoly V Skalny, Natalia V Simashkova, Tatiana P Klyushnik, Andrei R Grabeklis, Ivan V Radysh, Margarita G Skalnaya, Alexey A Tinkov
The primary objective of the present study is analysis of hair trace elements content in children with communication disorder (CD) and autism spectrum disorder (ASD). A total of 99 children from control, CD, and ASD groups (n = 33) were examined. All children were additionally divided into two subgroups according to age. Hair levels of trace elements were assessed using inductively coupled plasma mass spectrometry. The difference was considered significant at p < 0.01. The obtained data demonstrate that children with CD are characterized by significantly increased hair lithium (Li) (96 %; p = 0...
October 26, 2016: Biological Trace Element Research
https://www.readbyqxmd.com/read/27769745/determination-of-mercury-in-hair-comparison-between-gold-amalgamation-atomic-absorption-spectrometry-and-mass-spectrometry
#16
Francesco Domanico, Giovanni Forte, Costanza Majorani, Oreste Senofonte, Francesco Petrucci, Vincenzo Pezzi, Alessandro Alimonti
Mercury is a heavy metal that causes serious health problems in exposed subjects. The most toxic form, i.e., methylmercury (MeHg), is mostly excreted through human hair. Numerous analytical methods are available for total Hg analysis in human hair, including cold vapour atomic fluorescence spectrometry (CV-AFS), inductively coupled plasma mass spectrometry (ICP-MS) and thermal decomposition amalgamation atomic absorption spectrometry (TDA-AAS). The aim of the study was to compare the TDA-AAS with the ICP-MS in the Hg quantification in human hair...
September 29, 2016: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/27761855/whole-blood-and-hair-trace-elements-and-minerals-in-children-living-in-metal-polluted-area-near-copper-smelter-in-karabash-chelyabinsk-region-russia
#17
Anatoly V Skalny, Elena V Zhukovskaya, Galina N Kireeva, Margarita G Skalnaya, Andrey R Grabeklis, Ivan V Radysh, Rosa A Shakieva, Alexandr A Nikonorov, Alexey A Tinkov
The primary aim of the study is assessment of hair and whole blood trace element and mineral levels in children living in a polluted area near a copper smelter (Karabash) and two control locations (Varna, Tomino) using inductively coupled plasma mass spectrometry. The obtained data indicates that both blood and hair As, Pb, and Fe levels in children living in Karabash significantly exceeded the control values. Whole blood levels of copper in children living in Varna exceeded that in Tomino (p = 0.155) and Karabash (p < 0...
October 19, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27744484/beta-cyanoalanine-synthase-pathway-as-a-homeostatic-mechanism-for-cyanide-detoxification-as-well-as-growth-and-development-in-higher-plants
#18
Hafiz Mamoon Rehman, Zahid Hussain Shah, Muhammad Amjad Nawaz, Muhammad Qadir Ahmad, Seung Hwan Yang, Kang Hee Kho, Gyuhwa Chung
This review provides an insight into the beta-cyanoalanine synthase pathway in higher plants for cyanide (CN) detoxification and describes how it contributes to various physiological activities, such as plant growth and development. In higher plants, CN is produced as a natural toxin through the biosynthesis of ethylene and camalexin, the degradation of glucosinolates and cyanogenic glycosides, the oxidation of amino acids, and the metabolism of glyoxylate and hydroxylamine. To maintain cellular homeostasis by maintaining CN at non-toxic levels, plants have evolved four different biochemical pathways: the β-cyanoalanine synthase pathway (beta-CASP), the thiocyanate pathway, the formamide hydrolase pathway, and the natural release of CN through volatilization...
October 15, 2016: Planta
https://www.readbyqxmd.com/read/27736697/tradescantia-as-a-biomonitor-for-pesticide-genotoxicity-evaluation-of-iprodione-carbaryl-dimethoate-and-4-4-dde
#19
Ximena Fadic, Fabián Placencia, Ana María Domínguez, Francisco Cereceda-Balic
There is a current tendency to develop and apply environmentally friendly techniques that meet the requirements of green analytical chemistry as an alternative to conventional analytical methods. For toxicity evaluation, these alternatives may be found in bioassays such as Tradescantia. This technique, developed in the 1980s, is highly sensitive to evaluate environmental mutagens, simple and cheap. In this paper, the sensibility of both the Tradescantia micronucleus bioassay (Trad-MCN) and the Tradescantia stamen hair bioassay (Trad-SH) were studied for carbaryl, dimethoate and iprodione, common agricultural and domestic pesticides that are currently used in Chile, which have never been tested with such bioassays...
October 10, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27729914/reactive-oxygen-species-ros-beneficial-companions-of-plants-developmental-processes
#20
Rachana Singh, Samiksha Singh, Parul Parihar, Rohit K Mishra, Durgesh K Tripathi, Vijay P Singh, Devendra K Chauhan, Sheo M Prasad
Reactive oxygen species (ROS) are generated inevitably in the redox reactions of plants, including respiration and photosynthesis. In earlier studies, ROS were considered as toxic by-products of aerobic pathways of the metabolism. But in recent years, concept about ROS has changed because they also participate in developmental processes of plants by acting as signaling molecules. In plants, ROS regulate many developmental processes such as cell proliferation and differentiation, programmed cell death, seed germination, gravitropism, root hair growth and pollen tube development, senescence, etc...
2016: Frontiers in Plant Science
keyword
keyword
63459
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"