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Ronnie Ramadan, William E Boden, Scott Kinlay
No abstract text is available yet for this article.
March 31, 2018: Journal of the American Heart Association
Kathleen M Scott, John Williams, Cody M B Porter, Sydney Russel, Tara L Harmer, John H Paul, Kirsten M Antonen, Megan K Bridges, Gary J Camper, Christie K Campla, Leila G Casella, Eva Chase, James W Conrad, Mercedez C Cruz, Darren S Dunlap, Laura Duran, Elizabeth M Fahsbender, Dawn B Goldsmith, Ryan F Keeley, Matthew R Kondoff, Breanna I Kussy, Marannda K Lane, Stephanie Lawler, Brittany A Leigh, Courtney Lewis, Lygia M Lostal, Devon Marking, Paola A Mancera, Evan C McClenthan, Emily A McIntyre, Jessica A Mine, Swapnil Modi, Brittney D Moore, William A Morgan, Kaleigh M Nelson, Kimmy N Nguyen, Nicholas Ogburn, David G Parrino, Anangamanjari D Pedapudi, Rebecca P Pelham, Amanda M Preece, Elizabeth A Rampersad, Jason C Richardson, Christina M Rodgers, Brent L Schaffer, Nancy E Sheridan, Michael R Solone, Zachery R Staley, Maki Tabuchi, Ramond J Waide, Pauline W Wanjugi, Suzanne Young, Alicia Clum, Chris Daum, Marcel Huntemann, Natalia Ivanova, Nikos Kyrpides, Natalia Mikhailova, Krishnaveni Palaniappan, Manoj Pillay, T B K Reddy, Nicole Shapiro, Dimitrios Stamatis, Neha Varghese, Tanja Woyke, Rich Boden, Sharyn K Freyermuth, Cheryl A Kerfeld
Chemolithoautotrophic bacteria from the genera Hydrogenovibrio, Thiomicrorhabdus and Thiomicrospira are common, sometimes dominant, isolates from sulfidic habitats including hydrothermal vents, soda and salt lakes and marine sediments. Their genome sequences confirm their membership in a deeply branching clade of the Gammaproteobacteria. Several adaptations to heterogeneous habitats are apparent. Their genomes include large numbers of genes for sensing and responding to their environment (EAL- and GGDEF-domain proteins and methyl-accepting chemotaxis proteins) despite their small sizes (2...
March 9, 2018: Environmental Microbiology
Ajay Premkumar, William Godfrey, Michael B Gottschalk, Scott D Boden
BACKGROUND: Low back pain has a high prevalence and morbidity, and is a source of substantial health-care spending. Numerous published guidelines support the use of so-called red flag questions to screen for serious pathology in patients with low back pain. This paper examines the effectiveness of red flag questions as a screening tool for patients presenting with low back pain to a multidisciplinary academic spine center. METHODS: We conducted a retrospective review of the cases of 9,940 patients with a chief complaint of low back pain...
March 7, 2018: Journal of Bone and Joint Surgery. American Volume
Rich Boden, Kathleen M Scott, Alexander W Rae, Lee P Hutt
No abstract text is available yet for this article.
March 2018: International Journal of Systematic and Evolutionary Microbiology
Laura E Dixon, Julian R Greenwood, Stefano Bencivenga, Peng Zhang, James Cockram, Gregory Mellers, Kerrie Ramm, Colin Cavanagh, Steve M Swain, Scott A Boden
The flowers of major cereals are arranged on reproductive branches known as spikelets, which group together to form an inflorescence. Diversity for inflorescence architecture has been exploited during domestication to increase crop yields, and genetic variation for this trait has potential to further boost grain production. Multiple genes that regulate inflorescence architecture have been identified by studying alleles that modify gene activity or dosage; however, little is known in wheat. Here, we show TEOSINTE BRANCHED1 ( TB1 ) regulates inflorescence architecture in bread wheat ( Triticum aestivum ) by investigating lines that display a form of inflorescence branching known as "paired spikelets...
March 2018: Plant Cell
Lauren M Boden, Stephanie A Boden, Ajay Premkumar, Michael B Gottschalk, Scott D Boden
STUDY DESIGN: Retrospective analysis of prospectively collected data. OBJECTIVE: To create a data-driven triage system stratifying patients by likelihood of undergoing spinal surgery within one year of presentation. SUMMARY OF BACKGROUND DATA: Low back pain (LBP) and radicular lower extremity (LE) symptoms are common musculoskeletal problems. There is currently no standard data-derived triage process based on information that can be obtained prior to the initial physician-patient encounter to direct patients to the optimal physician type...
February 9, 2018: Spine
E Jean Finnegan, Brett Ford, Xiaomei Wallace, Filomena Pettolino, Patrick T Griffin, Robert J Schmitz, Peng Zhang, Jose M Barrero, Matthew J Hayden, Scott A Boden, Colin A Cavanagh, Steve M Swain, Ben Trevaskis
The number of rachis nodes (spikelets) on a wheat spike is a component of grain yield that correlates with flowering time. The genetic basis regulating flowering in cereals is well understood, but there are reports that flowering time can be modified at a high frequency by selective breeding, suggesting that it may be regulated by both epigenetic and genetic mechanisms. We investigated the role of DNA methylation in regulating spikelet number and flowering time by treating a semi-spring wheat with the demethylating agent, Zebularine...
February 10, 2018: Plant, Cell & Environment
Laura E Dixon, Stefano Bencivenga, Scott A Boden
No abstract text is available yet for this article.
January 23, 2018: Journal of Experimental Botany
Laura E Dixon, Alba Farré, E Jean Finnegan, Simon Orford, Simon Griffiths, Scott A Boden
FLOWERING LOCUS T (FT) is a central integrator of environmental signals that regulates the timing of vegetative to reproductive transition in flowering plants. In model plants, these environmental signals have been shown to include photoperiod, vernalization, and ambient temperature pathways, and in crop species, the integration of the ambient temperature pathway remains less well understood. In hexaploid wheat, at least 5 FT-like genes have been identified, each with a copy on the A, B, and D genomes. Here, we report the characterization of FT-B1 through analysis of FT-B1 null and overexpression genotypes under different ambient temperature conditions...
January 4, 2018: Plant, Cell & Environment
Rich Boden, Kathleen M Scott, Alexander W Rae, Lee P Hutt
The genus Thiomicrorhabdus (Tmr) in the Piskirickettsiaceae in the Thiotrichales of the Gammaproteobacteria contains four species of sulfur-oxidising obligate chemolithoautotroph with validly published names, all previously classified as Thiomicrospira (Tms) species. Here we demonstrate that Thiomicrospira hydrogeniphila, a recently published hydrogen-utilising chemolithoautotroph closely related to Thiomicrorhabdus frisia (type species of Thiomicrorhabdus) should be classified as a member of the genus Thiomicrorhabdus and not Thiomicrospira, as Thiomicrorhabdus hydrogeniphila comb...
October 2017: International Journal of Systematic and Evolutionary Microbiology
Antonio Serrano-Mislata, Stefano Bencivenga, Max Bush, Katharina Schiessl, Scott Boden, Robert Sablowski
DELLA proteins associate with transcription factors to control plant growth in response to gibberellin1 . Semi-dwarf DELLA mutants with improved harvest index and decreased lodging greatly improved global food security during the 'green revolution' in the 1960-1970s2 . However, DELLA mutants are pleiotropic and the developmental basis for their effects on plant architecture remains poorly understood. Here, we show that DELLA proteins have genetically separable roles in controlling stem growth and the size of the inflorescence meristem, where flowers initiate...
September 2017: Nature Plants
Rich Boden, Kathleen M Scott, John Williams, Sydney Russel, Kirsten Antonen, Alex W Rae, Lee P Hutt
Thiomicrospira(Tms) species are small sulfur-oxidizing chemolithoautotrophic members of the Gammaproteobacteria. Whilst the type species Tms. pelophila and closely related Tms. thyasirae exhibit canonical spiral morphology under sub-optimal growth conditions, most species are vibrios or rods. The 16S rRNA gene diversity is vast, with identities as low as 91.6 % for Tms. pelophila versus Tms. frisia, for example. Thiomicrospira was examined with closely related genera Hydrogenovibrio and Thioalkalimicrobium and, to rationalize organisms on the basis of the 16S rRNA gene phylogeny, physiology and morphology, we reclassify Tms...
May 2017: International Journal of Systematic and Evolutionary Microbiology
Scott D Boden, Brian T Smith, Matthew Handley
The next phase of health-care reform will accelerate the formation of integrated delivery systems and the creation of value and savings through population health management. Accomplishing this goal requires 3 key factors, including (1) enabling groups of physicians and hospitals to legally work together to cover a broad geographic area, (2) the formation of integrated delivery systems that cover the low to high-acuity and post-acute care spectrums, and (3) identifying mechanisms through which a subspecialty can impact the health of a population of patients...
May 3, 2017: Journal of Bone and Joint Surgery. American Volume
Scott A Boden
A defining characteristic of grasses, including major cereal crops, is the way in which flowers are arranged on an inflorescence. A new study finds that regulation of hormone levels during development is crucial for determining the arrangement of flowers on a barley inflorescence, opening new doors for increasing grain yield.
December 28, 2016: Nature Genetics
Brett Ford, Weiwei Deng, Jenni Clausen, Sandra Oliver, Scott Boden, Megan Hemming, Ben Trevaskis
An increase in global temperatures will impact future crop yields. In the cereal crops wheat and barley, high temperatures accelerate reproductive development, reducing the number of grains per plant and final grain yield. Despite this relationship between temperature and cereal yield, it is not clear what genes and molecular pathways mediate the developmental response to increased temperatures. The plant circadian clock can respond to changes in temperature and is important for photoperiod-dependent flowering, and so is a potential mechanism controlling temperature responses in cereal crops...
October 2016: Journal of Experimental Botany
Charles S Day, Scott D Boden, Patrick T Knott, Nancy C O'Rourke, Brian W Yang
Growth estimates and demographic shifts of the population of the United States foreshadow a future heightened demand for musculoskeletal care. Although many articles have discussed this growing demand on the musculoskeletal workforce, few address the inevitable need for more musculoskeletal care providers. As we are unable to increase the number of orthopaedic surgeons because of restrictions on graduate medical education slots, physician assistants (PAs) and nurse practitioners (NPs) represent one potential solution to the impending musculoskeletal care supply shortage...
June 1, 2016: Journal of Bone and Joint Surgery. American Volume
Weiwei Deng, Jenni Clausen, Scott Boden, Sandra N Oliver, M Cristina Casao, Brett Ford, Robert S Anderssen, Ben Trevaskis
No abstract text is available yet for this article.
2015: PloS One
Keith H Bridwell, Paul A Anderson, Scott D Boden, Han Jo Kim, Alexander Vaccaro, Jeffrey C Wang
No abstract text is available yet for this article.
June 17, 2015: Journal of Bone and Joint Surgery. American Volume
Michael B Gottschalk, Ajay Premkumar, Kyle Sweeney, Scott D Boden, John Heller, S Tim Yoon, John M Rhee, Steven K Leckie, Brett Braly, Andrew K Simpson, Eric Lenehan
STUDY DESIGN: Independent retrospective review of prospectively collected data, comparative cohort study. OBJECTIVE: The objective of this study was to compare the clinical, radiographical, and cost/value of the addition of an interbody arthrodesis (IBA) to a posterolateral arthrodesis (PLA) in the surgical treatment of L4-L5 degenerative spondylolisthesis (DS). The authors hypothesized that the addition of IBA to PLA would produce added value while incurring minimal additional costs...
June 15, 2015: Spine
Weiwei Deng, Jenni Clausen, Scott Boden, Sandra N Oliver, M Cristina Casao, Brett Ford, Robert S Anderssen, Ben Trevaskis
The plant circadian clock is an internal timekeeper that coordinates biological processes with daily changes in the external environment. The transcript levels of clock genes, which oscillate to control circadian outputs, were examined during early seedling development in barley (Hordeum vulgare), a model for temperate cereal crops. Oscillations of clock gene transcript levels do not occur in barley seedlings grown in darkness or constant light but were observed with day-night cycles. A dark-to-light transition influenced transcript levels of some clock genes but triggered only weak oscillations of gene expression, whereas a light-to-dark transition triggered robust oscillations...
2015: PloS One
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