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Vitreo-retinal interface

A Barthel, D Trematerra, M A Nasseri, D Zapp, C P Lohmann, A Knoll, M Maier
Vitreo-retinal surgery is challenging, as delicate structures have to be manipulated. Eliminating tremor caused by human motions when doing micromanipulation can therefore improve the outcome of such an intervention. An eye surgery robot has been built to overcome this problem. The contribution of this paper is the design of a telemanipulation setup for the robotic system. A telemanipulation setup using a haptic device featuring force feedback as a user interface for controlling a hybrid parallel-serial micromanipulator is designed and developed...
August 2015: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
E Denion, S Coffin-Pichonnet, A Degoumois, M-G Barcatali, T Beuste, A-L Lux
PURPOSE: To report beyond-the-edge proliferation (BTEP) after relaxing retinectomies (RR) i.e. fibrous sheets stretched between the RR edge and the far periphery; to evaluate the tractional potential and report the long-term course of BTEP. METHODS: Retrospective review of the medical records of 83 patients having undergone a RR between January 2009 and December 2014 to identify patients with BTEP. RESULTS: Six patients aged 31 to 76 were identified...
January 2016: Journal Français D'ophtalmologie
Padmamalini Mahendradas, Sumukh Madhu, Ankush Kawali, Indu Govindaraj, Poornachandra B Gowda, Anand Vinekar, Naren Shetty, Rohit Shetty, Bhujang K Shetty
BACKGROUND: Understanding the changes that occur in the choroid is of paramount importance in various uveitis entities. B-scan ultrasonography and indocyanine green angiography can be used to study choroid. Currently, spectral-domain optical coherence tomography is used as the standard noninvasive technique to study the choroid by enhanced depth imaging. Our aim was to study the structural visibility of the choroid using spectral-domain optical coherence tomography in the same area of interest in patients with uveitis with posterior segment manifestations using conventional, enhanced depth imaging (EDI), and combined depth imaging (CDI) techniques...
December 2014: Journal of Ophthalmic Inflammation and Infection
Yoshihiro Yonekawa, Benjamin J Thomas, Kimberly A Drenser, Michael T Trese, Antonio Capone
PURPOSE: The in vivo microstructural features of familial exudative vitreoretinopathy (FEVR) have not been well described. We present new anatomic features of FEVR with functional and genetic correlations. DESIGN: Consecutive, retrospective, observational case series. PARTICIPANTS: Patients with FEVR treated from 2009 to 2014. METHODS: We identified 346 patients with FEVR. Those imaged with spectral-domain optical coherence tomography (SD OCT) with or without enhanced depth imaging (EDI) were included, and images were correlated with best-corrected visual acuity (BCVA), widefield angiography, fundus autofluorescence (AF), and wnt signaling pathway mutations...
November 2015: Ophthalmology
K Gekeler, S Priglinger, F Gekeler, C Priglinger
BACKGROUND: The vitreoretinal interface is not merely the space between the vitreous body and the retina but it is also a site for highly complex pathologies with the vitreous body exerting an influence on all the neighbouring structures. METHODS: A literature search was performed in Pubmed and current book articles RESULTS: This review article highlights the role of the vitreous body in vitreomacular adhesion and traction, in the development of macular holes and epiretinal membranes as well as its role in age-related macular degeneration...
July 2015: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
Yuji Oshima, Rajendra S Apte, Shintaro Nakao, Shigeo Yoshida, Tatsuro Ishibashi
BACKGROUND: The pathogenesis of macular hole formation is widely accepted as a tractional force at the vitreo-retinal interface in fovea. We report a case of macular hole after intravitreous aflibercept injection for age-related macular degeneration (AMD) associated with contraction of the retinal pigment epithelium (RPE) at the edge of a fibrovascular pigment epithelial detachment (PED). CASE PRESENTATION: A 94-year old man with neovascular AMD affecting his left eye accompanied by a fibrovascular PED was examined for severe vision loss...
2015: BMC Ophthalmology
Li-Li Wu, Tzyy-Chang Ho, Chang-Hao Yang, Chung-May Yang
PURPOSE: To investigate the vitreoretinal relationship in eyes with full-thickness macular hole (FTMH) without retinal schisis or detachment. Eyes with and without high myopia were compared using slit-lamp biomicroscopy, optical coherence tomography (OCT), and intraoperative observations. METHODS: Clinical records of 34 consecutive cases of FTMH without schisis or detachment in highly myopic eyes (refractive error larger than -6.0 diopters or axial length >26 mm) were retrospectively reviewed...
January 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
Tomohiro Okamoto, Hajime Shinoda, Toshihide Kurihara, Norihiro Nagai, Kazuo Tsubota, Yoko Ozawa
BACKGROUND: Macular hole results from a tractional force at the vitreo-retinal interface which is developed by modification and subsequent degeneration of the posterior precortical vitreous and the internal limiting membrane (ILM). Meanwhile, the wet type of age-related macular degeneration (AMD) is caused by the submacular formation of choroidal neovascularization (CNV). Although exudative changes derived from CNV may cause epiretinal membrane (ERM) formation, which can also cause tractional force at the vitreo-retinal interface, there have been few reports of AMD-associated macular hole development in which the full thickness of the retinal tissue is completely torn by the tractional force...
2014: BMC Ophthalmology
Matthias Bolz, Jan Lammer, Gabor Deak, Andreas Pollreisz, Christoph Mitsch, Christoph Scholda, Michael Kundi, Ursula Schmidt-Erfurth
AIM: To analyse a new grading protocol for clinically significant diabetic macular oedema (CSME) based on spectral domain optical coherence tomography (SD-OCT) and fluorescein angiography (FA). METHODS: 56 eyes of 40 patients with CSME were examined by Cirrus OCT (Carl Zeiss Meditec), Spectralis HRA and OCT (Heidelberg Engineering) on the same day. Three graders analysed images based on a newly developed grading protocol integrating all relevant information from OCT and FA...
December 2014: British Journal of Ophthalmology
Sivakami A Pai, Nazimul Hussain, Sudhira P Hebri, Afra M Lootah, Moza A Dekhain
In this article we herein report an interesting vitreo-macular interface abnormality associated with chronic diabetic cystoid macular edema. It is an observational case study of three diabetic patients examined in the diabetic clinic. All the patients had proliferative diabetic retinopathy with chronic macular edema. A serial cross sectional OCT examination and tracking of both the longitudinal progression of macular thickening and vitreo-macular interface revealed cystoid macular edema with a characteristic hyperreflective vitreous shadow emerging from the vitreofoveal interface...
April 2014: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
Ajit Babu Majji, Jay Kumar Chhablani, Bupesh Bagga
AIM: To study the vitreo-retinal interface and macular changes on optical coherence tomography (OCT) in the fellow eyes of patients with macular hole. METHODS: Patients with idiopathic macular hole in one or both eyes presented to our institute between January 2003 and December 2009 were evaluated retrospectively. Demographic details, best-corrected visual acuity and vitreo-retinal interface, and macular changes of the fellow eye on OCT were studied. RESULTS: Seventy patients underwent OCT of both eyes during the study period...
2013: International Journal of Ophthalmology
Magdalena Grzymowicz-Leciak, Piotr Jurowski
The aim of the article is to present the role of SOCT in monitoring the treatment of Birdshot chorioretinopathy based on a clinical case. A 78 years old woman with Birdshot retinopathy was referred to the Department of Ophthalmology for visual deterioration since 2 months. The patient complained about blurred vision and floaters. Eye examination revealed changes on the fundus typical for birdshot chorioretinopathy. Two years of regular checking and SOCT scans allowed for better monitoring and modification of treatment both with steroids and with non steroid immunosuppressive agents...
2012: Klinika Oczna
Leo H N Sheck, Callum J Wilson, Andrea L Vincent
Fundal opacities have been reported in patients with Gaucher disease, a rare autosomal recessive lysosomal storage disease, prior to the advent of optical coherent tomography. This report provides a detailed analysis of the fundal opacities in a 14-year-old girl with genetically proven Gaucher disease using spectral domain optical coherent tomography. It illustrates clearly that these opacities were pre-retinal opacities located at the vitreo-retinal interface associated with localized posterior vitreous detachments, rather than vitreous opacities as previously suggested in the literature...
December 2012: Ophthalmic Genetics
M R Romano, J L Vallejo-Garcia, F I Camesasca, P Vinciguerra, C Costagliola
PURPOSE: To determine the incidence of vitreopapillary adhesion (VPA) and to investigate its value as a prognostic factor in the surgical outcome of pseudo- (PMH) and lamellar macular holes (LMH). METHODS: A total of 76 consecutive patients, diagnosed with PMH (41 eyes) or LMH (35 eyes) were included. Eyes with VPA were alternatively assigned to the surgical or control group. Surgery consisted of a 25G vitrectomy and internal limiting membrane peeling with blue dye staining...
June 2012: Eye
A Shrestha, N Maharjan, A Shrestha, R Thapa, G Poudyal
INTRODUCTION: The topographic mapping is useful for monitoring patients for the development of macular edema and following the resolution of edema after laser treatment. OBJECTIVES: To evaluate the usefulness of optical coherence tomography (OCT) for mapping of macula after laser therapy in clinically significant macular edema (CSME). MATERIALS AND METHODS: A prospective study was carried out enrolling 60 eyes of 35 patients with the diagnosis of CSME...
January 2012: Nepalese Journal of Ophthalmology
Masako Kuroda, Yasuhiko Hirami, Akihiro Nishida, Zi-Bing Jin, Chie Ishigami, Masayo Takahashi, Yasuo Kurimoto
BACKGROUND: Oguchi disease is a form of congenital stationary night-blindness characterized by a golden tapetal fundus reflex. This reflex is known to disappear in the dark-adapted state ("Mizuo-Nakamura phenomenon"). The origin of the reflex is not clear. We report a case of Oguchi disease with the disappearance of the golden tapetal reflex after vitreous resection. CASE: An 80-year-old man was referred for rhegmatogenous retinal detachment of the left eye. Golden tapetal reflex was observed in both eyes...
October 2011: Nippon Ganka Gakkai Zasshi
Amy E Green-Simms, Sophie J Bakri
The interaction between the vitreous and the internal limiting membrane of the retina is important in the pathoetiology of numerous ocular disease processes. Recent studies have focused on the vitreo-retinal interface in the context of age-related macular degeneration (AMD), linking vitreo-retinal adhesion to exudative AMD in particular. This review summarizes our knowledge of vitreous anatomy and recent investigations regarding vitreomacular adhesion and AMD.
May 2011: Seminars in Ophthalmology
Jacek Robaszkiewicz, Katarzyna Chmielewska, Małgorzata Figurska, Joanna Wierzbowska, Andrzej Stankiewicz
The key to identifying the type of diabetic maculopathy is determining the status of posterior vitreous adhesion. In the pathological state, the breakdown of the internal and external blood-retina barrier is evident, however the mechanism is usually complex. The common denominator for these disorders are Müller glial cells, which mediate in maintaining the blood-retina barrier by linking the vessels, neurons and the vitreous in anatomical network and into functional dependence. The breakdown of the blood-retina barrier results in proliferation of Müller cells...
2010: Klinika Oczna
Ahmed M Abu El-Asrar, Hani S Al-Mezain
Diabetic retinopathy remains a major cause of worldwide preventable blindness. The vitreo-retinal interface plays a critical role in the pathogenesis of diabetic retinopathy. The term pharmacologic vitreolysis refers to the use of enzymes to liquefy the vitreous gel, and to induce posterior vitreous detachment (PVD). Intravitreal ovine hyaluronidase injection was effective in clearing vitreous hemorrhage. Several human case series demonstrated that intravitreal injection of autologous plasmin enzyme was a safe and effective adjunct to vitreous surgery for the treatment of diabetic macular edema and proliferative diabetic retinopathy...
March 1, 2011: Current Pharmaceutical Biotechnology
Elaine de Paula Fiod Costa, Eduardo B Rodrigues, Michel E Farah, Jerry Sebag, Carsten H Meyer
Vitreous constitutes about 80% of the volume of the human eye. It is an extended extracellular matrix that is composed of collagen, hyaluronan, and other extracellular matrix molecules, but mostly water. In both health as well as disease, especially diabetic retinopathy (DR), special attention should be drawn to the posterior vitreous cortex and its relation to the retinal surface. The important role of vitreous in the pathogenesis of proliferative DR has already been demonstrated by several experimental and clinical studies...
March 1, 2011: Current Pharmaceutical Biotechnology
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