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Separation Anxiety

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https://www.readbyqxmd.com/read/28213818/acceptability-of-an-internet-cognitive-behavioural-therapy-program-for-people-with-early-stage-cancer-and-cancer-survivors-with-depression-and-or-anxiety-thematic-findings-from-focus-groups
#1
A Karageorge, M J Murphy, J M Newby, L Kirsten, G Andrews, K Allison, S Loughnan, M Price, J Shaw, H Shepherd, J Smith, P Butow
PURPOSE: We developed an eight-lesson internet-delivered CBT (iCBT) program targeting anxiety and depression in early-stage cancer and cancer survivors. To explore the acceptability of the program, we showed volunteers the first two lessons and asked for their views. METHODS: Focus groups (n = 3) and individual interviews (n = 5) were undertaken with 15 participants (11 survivors) with mainly breast (11 of the 15) cancer, who had reviewed intervention materials...
February 18, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28212910/-to-see-with-my-own-eyes-experiences-of-family-visits-during-phase-1-recovery
#2
M Cecilia Wendler, Katherine Smith, Wanda Ellenburg, Rita Gill, Lea Anderson, Kim Spiegel-Thayer
PURPOSE: Long separations are a characteristic of the day of surgery, keeping patients and their family members waiting and apart. At a time of high vulnerability, these separations can cause anxiety and worry. The purpose of this study was to identify the outcomes and experiences of patients and family members who engaged in a 5- to 10-minute supervised family visit during phase I postanesthesia recovery. DESIGN: This was a descriptive, single-group, mixed-methods study...
February 2017: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/28202350/chronic-social-instability-increases-anxiety-like-behavior-and-ethanol-preference-in-male-long-evans-rats
#3
Alyssa R Roeckner, Alexandra Bowling, Tracy R Butler
Chronic stress during adolescence is related to increased prevalence of anxiety disorders and alcohol use disorders in humans. This phenotype has been consistently recapitulated in animal models with male subjects, but models using female subjects are fewer. The aim of these studies was to test the hypothesis that chronic social instability (CSI) during adolescence engenders increased anxiety-like behavior, increased corticosterone, and greater ethanol intake and/or preference than control groups in male and female rats...
February 13, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28195139/altered-insula-connectivity-under-mdma
#4
Ishan C Walpola, Timothy Nest, Leor Roseman, David Erritzoe, Amanda Feilding, David J Nutt, Robin L Carhart-Harris
Recent work with noninvasive human brain imaging has started to investigate the effects of 3, 4-methylenedioxymethamphetamine (MDMA) on large-scale patterns of brain activity. MDMA, a potent monoamine-releaser with particularly pronounced serotonin- releasing properties, has unique subjective effects that include: marked positive mood, pleasant/unusual bodily sensations and pro-social, empathic feelings. However, the neurobiological basis for these effects is not properly understood, and the present analysis sought to address this knowledge gap...
February 14, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28194191/prediction-of-clinical-peanut-allergy-status-among-children-in-hamilton-ontario-using-chart-review-data-collected-during-2012-2015
#5
Elizabeth Simms, Gary Foster, Katherine Arias, Mark Larché, Tosha Freitag, Tina Walker, Susanna Goncharova, Andrea Marrin, Andreas Freitag, Manel Jordana, Susan Waserman
BACKGROUND: Peanut sensitization does not necessarily indicate clinical peanut allergy, and uncertainty as to whether or not there is true peanut allergy can lead to increased anxiety and decreased quality of life for patients and their families. The gold standard for diagnosing clinical peanut allergy is the oral food challenge, but this method is time-consuming and can cause severe allergic reactions. It would therefore be beneficial to develop a tool for predicting clinical peanut allergy in peanut-sensitized individuals whose peanut allergy status is unknown so as to better determine who requires an oral food challenge for diagnosis...
2017: Allergy, Asthma, and Clinical Immunology
https://www.readbyqxmd.com/read/28192622/the-safety-and-efficacy-of-baclofen-to-reduce-alcohol-use-in-veterans-with-chronic-hepatitis-c-a-randomized-clinical-trial
#6
Peter Hauser, Bret Fuller, Samuel B Ho, Paul Thuras, Shira Kern, Eric Dieperink
BACKGROUND AND AIMS: Alcohol use disorders (AUDs) are common among people with chronic hepatitis C (HCV) and accelerate the development of fibrosis and cirrhosis caused by HCV. Baclofen, a gamma-aminobutyric acid (GABA) beta-receptor agonist, differs from medications for AUDs currently approved by the United States (US) Federal Drug Administration (FDA) as it is metabolized primarily through the kidneys. The primary outcome of this study was to compare baclofen with a placebo in the percentage of days abstinent from alcohol...
February 13, 2017: Addiction
https://www.readbyqxmd.com/read/28189098/telmisartan-attenuates-diabetes-induced-depression-in-rats
#7
Urmila Aswar, Shilpa Chepurwar, Sumit Shintre, Manoj Aswar
BACKGROUND: Role of brain renin angiotensin system (RAS) is well understood and various clinical studies have proposed neuroprotective effects of ARB's. It is also assumed that diabetic depression is associated with activation of brain RAS, HPA axis dysregulation and brain inflammatory events. Therefore, the present study was designed to investigate the antidepressant effect of low dose telmisartan (TMS) in diabetes induced depression (DID) in rats. METHODS: Diabetes was induced by injecting streptozotocin...
December 9, 2016: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/28189078/prevalence-and-associated-factors-of-anxiety-and-depression-among-patients-with-chronic-respiratory-diseases-in-eight-general-hospitals-in-jiangsu-province-of-china-a-cross-sectional-study
#8
Xianmei Zhou, Jiashu Li, Wei Gu, Jian Wang, Yimin Zhu, Guicai Zhang, Yuanhua Ding, Yanfen Tang
Anxiety and depression are two common psychological disorders with high morbidity worldwide. Understanding of their prevalence of patients with chronic respiratory diseases is becoming more and more important for clinicians. The current study aims at investigation of the prevalence and potential risk factors of anxiety and depression among patients with chronic respiratory diseases. The psychological status, anxiety and depression, and the relevant risk factors of 1713 patients with chronic respiratory diseases from 8 general hospitals in Jiangsu Province of China were evaluated...
January 25, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28188857/sensitivity-to-carbon-dioxide-and-translational-studies-of-anxiety-disorders
#9
Marco Battaglia
Heightened concentrations of CO2 in inhaled air provoke temporary acidification of the brain, followed by compensatory hyperventilation and increased arousal/anxiety. These responses are likely to map a basic, latent general alarm/avoidance system that is largely shared across mammals, and are sources of individual differences. By showing paroxysmal respiratory and emotional responses to CO2 challenges, humans with panic and separation anxiety disorders lie at one extreme of the distribution for CO2 sensitivity...
February 7, 2017: Neuroscience
https://www.readbyqxmd.com/read/28188472/the-effect-of-postpartum-depression-and-current-mental-health-problems-of-the-mother-on-child-behaviour-at-eight-years
#10
R Closa-Monasterolo, M Gispert-Llaurado, J Canals, V Luque, M Zaragoza-Jordana, B Koletzko, V Grote, M Weber, D Gruszfeld, K Szott, E Verduci, A ReDionigi, J Hoyos, G Brasselle, J Escribano Subías
Background Maternal postpartum depression (PPD) could affect children's emotional development, increasing later risk of child psychological problems. The aim of our study was to assess the association between child's emotional and behavioural problems and mother's PPD, considering maternal current mental health problems (CMP). Methods This is a secondary analysis from the EU-Childhood Obesity Project (NCT00338689). Women completed the Edinburgh Postnatal Depression Scale (EPDS) at, 2, 3 and 6 months after delivery and the General Health Questionnaire (GHQ-12) to assess CMP once the children reached the age of 8 years...
February 11, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28185885/behavioral-effects-in-adolescence-and-early-adulthood-in-two-length-models-of-maternal-separation-in-male-rats
#11
María Banqueri, Marta Méndez, Jorge L Arias
Maternal separation (MS) is an extensively used early life stress model. There is some variability in the MS lengths used. Maternal separation leads to emotional and behavioral alterations such as anxiety, despair, or memory problems. We performed MS in Wistar rats with two length models from postnatal day 1 until day 10 and from postnatal day 1 until day 21 during 4hours per day in both groups. We performed a test battery of a wide range of behaviors to measure anxiety, despair, prepulse inhibition, recognition memory, and associative memory both in adolescent and adult subjects...
February 6, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28184167/heat-pain-detection-threshold-is-associated-with-the-area-of-secondary-hyperalgesia-following-brief-thermal-sensitization-a-study-of-healthy-male-volunteers
#12
Morten Sejer Hansen, Jørn Wetterslev, Christian Bressen Pipper, Mohammad Sohail Asghar, Jørgen Berg Dahl
INTRODUCTION: The area of secondary hyperalgesia following brief thermal sensitization (BTS) of the skin and heat pain detection thresholds (HPDT) may both have predictive abilities in regards to pain sensitivity and clinical pain states. The association between HPDT and secondary hyperalgesia, however, remains unsettled, and the dissimilarities in physiologic properties suggest that they may represent 2 distinctively different pain entities. The aim of this study was to investigate the association between HPDT and BTS-induced secondary hyperalgesia...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28178272/psychobiological-factors-affecting-cortisol-variability-in-human-dog-dyads
#13
Iris Schöberl, Manuela Wedl, Andrea Beetz, Kurt Kotrschal
Stress responses within dyads are modulated by interactions such as mutual emotional support and conflict. We investigated dyadic psychobiological factors influencing intra-individual cortisol variability in response to different challenging situations by testing 132 owners and their dogs in a laboratory setting. Salivary cortisol was measured and questionnaires were used to assess owner and dog personality as well as owners' social attitudes towards the dog and towards other humans. We calculated the individual coefficient of variance of cortisol (iCV = sd/mean*100) over the different test situations as a parameter representing individual variability of cortisol concentration...
2017: PloS One
https://www.readbyqxmd.com/read/28168894/effect-of-combined-opioid-receptor-and-%C3%AE-2-adrenoceptor-blockade-on-anxiety-and-electrically-evoked-startle-responses
#14
Lechi Vo, Peter D Drummond
The R3 component of the electrically evoked blink reflex may form part of a startle reaction. Acoustic startle responses are augmented by yohimbine, an α2-adrenoceptor antagonist that blocks α2-autoreceptors, and are potentiated by opioid receptor blockade. To investigate these influences on electrically evoked startle responses, 16 mg yohimbine, with (16 participants) or without 50 mg naltrexone (23 participants), was administered in separate double-blind placebo-controlled cross-over experiments. In each experiment, R3 (a probable component of the startle response) was examined before and after high-frequency electrical stimulation of the forearm, a procedure that initiates inhibitory pain controls...
January 1, 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28165762/extended-release-guanfacine-in-pediatric-anxiety-disorders-a-pilot-randomized-placebo-controlled-trial
#15
Jeffrey R Strawn, Scott N Compton, Brigitte Robertson, Anne Marie Albano, Mohamed Hamdani, Moira A Rynn
OBJECTIVE: This is a feasibility study evaluating the safety, tolerability, and potential anxiolytic efficacy of the α2 agonist guanfacine extended-release (GXR) in children and adolescents with generalized anxiety disorder (GAD), separation anxiety disorder (SAD), or social phobia/social anxiety disorder. METHODS: Youth aged 6-17 years with a primary diagnosis of GAD, SAD, and/or social anxiety disorder were treated with flexibly dosed GXR (1-6 mg daily, n = 62) or placebo (n = 21) for 12 weeks...
February 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/28164996/personality-and-augmenting-reducing-a-r-in-auditory-event-related-potentials-erps-during-emotional-visual-stimulation
#16
Vilfredo De Pascalis, Francesca Fracasso, Philip J Corr
An auditory augmenting/reducing ERP paradigm recorded for 5 intensity tones with emotional visual stimulation was used, for the first time, to test predictions derived from the revised Reinforcement Sensitivity Theory (rRST) of personality with respect to two major factors: behavioral inhibition system (BIS), fight/flight/freeze system (FFFS). Higher BIS and FFFS scores were negatively correlated with N1/P2 slopes at central sites (C3, Cz, C4). Conditional process analysis revealed that the BIS was a mediator of the association between the N1/P2 slope and the FFFS scores...
February 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28164167/neonatal-maternal-separation-increases-susceptibility-to-experimental-colitis-and-acute-stress-exposure-in-male-mice
#17
Isabella M Fuentes, Natalie K Walker, Angela N Pierce, Briana R Holt, Elizabeth R Di Silvestro, Julie A Christianson
Experiencing early life stress can result in maladjusted stress response via dysregulation of the hypothalamic-pituitary-adrenal axis and serves as a risk factor for developing chronic pelvic pain disorders. We investigated whether neonatal maternal separation (NMS) would increase susceptibility to experimental colitis or exposure to acute or chronic stress. Male mice underwent NMS from postnatal day 1-21 and as adults were assessed for open field behavior, hindpaw sensitivity, and visceromotor response (VMR) to colorectal distension (CRD)...
December 2016: IBRO Rep
https://www.readbyqxmd.com/read/28161874/mindfulness-and-pharmacological-prophylaxis-after-withdrawal-from-medication-overuse-in-patients-with-chronic-migraine-an-effectiveness-trial-with-a-one-year-follow-up
#18
Licia Grazzi, Emanuela Sansone, Alberto Raggi, Domenico D'Amico, Andrea De Giorgio, Matilde Leonardi, Laura De Torres, Francisco Salgado-García, Frank Andrasik
BACKGROUND: Chronic Migraine (CM) is a disabling condition, worsened when associated with Medication Overuse (MO). Mindfulness is an emerging technique, effective in different pain conditions, but it has yet to be explored for CM-MO. We report the results of a study assessing a one-year course of patients' status, with the hypothesis that the effectiveness of a mindfulness-based approach would be similar to that of conventional prophylactic treatments. METHODS: Patients with CM-MO (code 1...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28161446/drunk-bugs-chronic-vapour-alcohol-exposure-induces-marked-changes-in-the-gut-microbiome-in-mice
#19
Veronica L Peterson, Nicholas J Jury, Raúl Cabrera-Rubio, Lorraine A Draper, Fiona Crispie, Paul D Cotter, Timothy G Dinan, Andrew Holmes, John F Cryan
The gut microbiota includes a community of bacteria that play an integral part in host health and biological processes. Pronounced and repeated findings have linked gut microbiome to stress, anxiety, and depression. Currently, however, there remains only a limited set of studies focusing on microbiota change in substance abuse, including alcohol use disorder. To date, no studies have investigated the impact of vapour alcohol administration on the gut microbiome. For research on gut microbiota and addiction to proceed, an understanding of how route of drug administration affects gut microbiota must first be established...
February 1, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28154542/the-modified-abbreviated-math-anxiety-scale-a-valid-and-reliable-instrument-for-use-with-children
#20
Emma Carey, Francesca Hill, Amy Devine, Dénes Szűcs
Mathematics anxiety (MA) can be observed in children from primary school age into the teenage years and adulthood, but many MA rating scales are only suitable for use with adults or older adolescents. We have adapted one such rating scale, the Abbreviated Math Anxiety Scale (AMAS), to be used with British children aged 8-13. In this study, we assess the scale's reliability, factor structure, and divergent validity. The modified AMAS (mAMAS) was administered to a very large (n = 1746) cohort of British children and adolescents...
2017: Frontiers in Psychology
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