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https://www.readbyqxmd.com/read/28644573/characteristics-of-integrons-and-associated-gene-cassettes-in-antibiotic-resistant-escherichia-coli-isolated-from-free-ranging-food-animals-in-china
#1
Mujeeb Ur Rehman, Hui Zhang, Shucheng Huang, Muhammad Kashif Iqbal, Khalid Mehmood, Houqiang Luo, Jiakui Li
We investigated the occurrence of integrons in antibiotic-resistant Escherichia coli strains isolated from free-ranging food animals, including yaks, piglets, and chickens, in China, and characterized the gene cassettes harbored within the integrons. We examined 432 E. coli strains that exhibited resistance to at least one class of antibiotics. Integrase genes and associated gene cassettes were characterized by polymerase chain reaction (PCR) analysis, restriction fragment-length polymorphism, DNA sequencing, conjugation experiments, and plasmid analysis...
June 23, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28634813/long-term-excessive-selenium-supplementation-induces-hypertension-in-rats
#2
Denise Grotto, Maria Fernanda Hornos Carneiro, Michele Mazzaron de Castro, Solange Cristina Garcia, Fernando Barbosa Junior
Selenium (Se) is an essential trace element involved in several biological pathways, naturally found in rocks, soils, and food. Even though the daily requirement of Se is achieved through a balanced diet, the use of Se supplements has been frequent. Due to the risk of toxic effects of having Se in excess, supplementation is still under debate. The aim was to evaluate the effects of long-term Se supplementation upon systolic blood pressure (SBP) and redox status of rats exposed to sodium selenite. Male Wistar rats were exposed to 2 and 6 mg/L of sodium selenite in drinking water for 85 days...
June 20, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28622847/historic-scale-and-persistence-of-drill-cuttings-impacts-on-north-sea-benthos
#3
Lea-Anne Henry, Dan Harries, Paul Kingston, J Murray Roberts
Despite its long history of hydrocarbon exploitation, the United Kingdom lacks scientific protocols to monitor ecological impacts of drill cuttings (mixtures between rocky material excavated from wells and drilling mud). The present study used the UK Benthos industry database to apply standardised variance partitioning and measure the scale and persistence of these effects at 19 sites across the UK sector of the North Sea. Generally, effects were limited to within 1 km from the platform, but two platforms historically drilled with oil-based mud were impacted up to 1...
May 31, 2017: Marine Environmental Research
https://www.readbyqxmd.com/read/28618659/projected-impact-of-climate-change-and-chemical-emissions-on-the-water-quality-of-the-european-rivers-rhine-and-meuse-a-drinking-water-perspective
#4
Rosa M A Sjerps, Thomas L Ter Laak, Gertjan J J G Zwolsman
Low river discharges of the rivers Rhine and Meuse are expected to occur more often and more prolonged in a changing climate. During these dry periods the dilution of point sources such as sewage effluents is reduced leading to a decline in chemical water quality. This study projects chemical water quality of the rivers Rhine and Meuse in the year 2050, based on projections of chemical emissions and two climate scenarios: moderate and fast climate change. It focuses on specific compounds known to be relevant to drinking water production, i...
June 10, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28612260/utility-of-spherical-human-liver-microtissues-for-prediction-of-clinical-drug-induced-liver-injury
#5
William R Proctor, Alison J Foster, Jennifer Vogt, Claire Summers, Brian Middleton, Mark A Pilling, Daniel Shienson, Monika Kijanska, Simon Ströbel, Jens M Kelm, Paul Morgan, Simon Messner, Dominic Williams
Drug-induced liver injury (DILI) continues to be a major source of clinical attrition, precautionary warnings, and post-market withdrawal of drugs. Accordingly, there is a need for more predictive tools to assess hepatotoxicity risk in drug discovery. Three-dimensional (3D) spheroid hepatic cultures have emerged as promising tools to assess mechanisms of hepatotoxicity, as they demonstrate enhanced liver phenotype, metabolic activity, and stability in culture not attainable with conventional two-dimensional hepatic models...
June 13, 2017: Archives of Toxicology
https://www.readbyqxmd.com/read/28611466/satellite-tagging-of-mediterranean-fin-whales-working-towards-the-identification-of-critical-habitats-and-the-focussing-of-mitigation-measures
#6
Simone Panigada, Gregory P Donovan, Jean-Noël Druon, Giancarlo Lauriano, Nino Pierantonio, Enrico Pirotta, Margherita Zanardelli, Alexandre N Zerbini, Giuseppe Notarbartolo di Sciara
Mediterranean fin whales comprise a genetically distinct population, listed as Vulnerable (VU) in the IUCN Red List. Collisions with vessels are believed to represent the main cause of human-induced mortality. The identification of critical habitats (including migration routes) incorporating satellite telemetry data is therefore crucial to develop focussed conservation efforts. Between 2012 and 2015 thirteen fin whales were equipped with satellite transmitters, 8 in the Pelagos Sanctuary (although two ceased within two days) and 5 in the Strait of Sicily, to evaluate movements and habitat use...
June 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28611320/prevalence-of-low-back-pain-and-carpal-tunnel-syndrome-among-dental-practitioners-in-dakshina-kannada-and-coorg-district
#7
D Anupama Prasad, Drithi Appachu, Vinayak Kamath, D Krishna Prasad
CONTEXT: Dental practitioners who usually have to work for long durations in a particular fixed posture are more prone to musculoskeletal disorders (MSDs), particularly those involving the hand and wrist and also of the lower back. AIMS: To study the prevalence of carpal tunnel syndrome (CTS) and low back pain (LBP) among dental practitioners and to correlate the symptoms with the duration of practice. SUBJECTS AND METHODS: A closed-end questionnaire was distributed to 100 dental practitioners from Dakshina Kannada and Coorg districts of Karnataka, India...
March 2017: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/28606448/platelet-transfusion-in-thrombocytopenic-cancer-patients-sometimes-justified-but-likely-insidious
#8
REVIEW
Thierry Burnouf, Mohamed Elemary, Julia Radosevic, Jerard Seghatchian, Hadi Goubran
The transfusion of platelet concentrates prepared from allogeneic single or pooled donations is a standard procedure in transfusion medicine to stop or prevent bleeding in cancer patients with thrombocytopenia undergoing surgery, chemotherapy and/or radiotherapy. While platelet transfusion may appear reasonable in many instances, greater scientific and medical attention should however be given to the possibly insidious impact of transfused platelets on the outcome of cancers. Indeed platelets and the microvesicles they release possess all the biological ingredients capable of supporting tumor growth, protecting circulating tumor cells, and to contributing to metastatic invasion...
May 26, 2017: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/28601370/impact-of-periodontal-treatment-on-hospitalization-for-adverse-respiratory-events-in-asthmatic-adults-a-propensity-matched-cohort-study
#9
Te-Chun Shen, Pei-Ying Chang, Cheng-Li Lin, Chang-Ching Wei, Chih-Yen Tu, Te-Chun Hsia, Chuen-Ming Shih, Wu-Huei Hsu, Fung-Chang Sung, Chia-Hung Kao
BACKGROUND: Periodontal disease is prevalent in asthmatics, but it is unclear whether periodontal treatment plays a role in adverse respiratory events in these patients. We evaluated risk of hospitalization for adverse respiratory events (acute exacerbation, pneumonia, and acute respiratory failure) and mortality in asthmatic adults with and without periodontal treatment. METHODS: We used National Health Insurance (NHI) claims data of Taiwan to identify 4771 asthmatic adults with periodontal disease who underwent periodontal treatment during 2000-2006...
June 7, 2017: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/28601041/results-of-domestic-migration-on-juvenile-delinquency-in-adana-turkey
#10
Sunay Firat, Yigit Iltas, Mete K Gulmen
OBJECTIVE: The aim of this study is to determine the effect of migration on children in the juvenile justice system. The study takes into account whether these children arrived in the city via migration or not, the types of crimes against property and persons committed by the children brought before the Juvenile Courts, and the types, frequency, and durations of punishments and precautionary decisions they received. In addition, the study examines the children's ability to realize the meaning and consequences of their crimes and to lead their future behaviors effectively...
July 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28597223/the-irrelevance-of-the-risk-uncertainty-distinction
#11
Dominic Roser
Precautionary Principles are often said to be appropriate for decision-making in contexts of uncertainty such as climate policy. Contexts of uncertainty are contrasted to contexts of risk depending on whether we have probabilities or not. Against this view, I argue that the risk-uncertainty distinction is practically irrelevant. I start by noting that the history of the distinction between risk and uncertainty is more varied than is sometimes assumed. In order to examine the distinction, I unpack the idea of having probabilities, in particular by distinguishing three interpretations of probability: objective, epistemic, and subjective probability...
June 8, 2017: Science and Engineering Ethics
https://www.readbyqxmd.com/read/28583817/wood-stove-pollution-in-the-developed-world-a-case-to-raise-awareness-among-pediatricians
#12
Lisa B Rokoff, Petros Koutrakis, Eric Garshick, Margaret R Karagas, Emily Oken, Diane R Gold, Abby F Fleisch
Use of wood for residential heating is regaining popularity in developed countries. Currently, over 11 million US homes are heated with a wood stove. Although wood stoves reduce heating costs, wood smoke may adversely impact child health through the emission of gaseous and particulate air pollutants. Our purpose is to raise awareness of this environmental health issue among pediatricians. To summarize the state of the science, we performed a narrative review of articles published in PubMed and Web of Science...
June 2, 2017: Current Problems in Pediatric and Adolescent Health Care
https://www.readbyqxmd.com/read/28578104/assessing-food-allergy-risks-from-residual-peanut-protein-in-highly-refined-vegetable-oil
#13
W Marty Blom, Astrid G Kruizinga, Carina M Rubingh, Ben C Remington, René W R Crevel, Geert F Houben
Refined vegetable oils including refined peanut oil are widely used in foods. Due to shared production processes, refined non-peanut vegetable oils can contain residual peanut proteins. We estimated the predicted number of allergic reactions to residual peanut proteins using probabilistic risk assessment applied to several scenarios involving food products made with vegetable oils. Variables considered were: a) the estimated production scale of refined peanut oil, b) estimated cross-contact between refined vegetable oils during production, c) the proportion of fat in representative food products and d) the peanut protein concentration in refined peanut oil...
May 31, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28568977/reproductive-performance-and-expression-of-imprinted-genes-in-somatic-cell-cloned-boars
#14
Tatsuo Kawarasaki, Satoko Enya, Masayoshi Otake, Masatoshi Shibata, Satoshi Mikawa
To assess the performance of boars derived by somatic cell cloning, we analyzed various aspects of their reproductive characteristics and the expression of two imprinted genes. Cloned boars (cloned Duroc × Jinhua) were analyzed for birth weight, growth rate, age at first ejaculation, semen characteristics and fertility, in comparison with naturally bred control boars of the same strain. The expression of imprinted genes was analyzed using the microsatellite marker SWC9 for the paternally expressed gene insulin-like growth factor -2 (IGF2) and with single nucleotide polymorphisms (SNPs) for the gene maternally expressed 3 (MEG3)...
June 1, 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/28558484/confidence-of-irb-rec-members-in-their-assessments-of-human-research-risk-a-study-of-irb-rec-decision-making-in-action
#15
Frederick Grinnell, John Z Sadler, Victoria McNamara, Kristen Senetar, Joan Reisch
Understanding how institutional review boards/research ethics committees (IRBs/RECs) perform risk/benefit assessment is important to help improve their function. In environmental ethics, uncertainty about potential outcomes and the precautionary principle play important roles in regulatory oversight but have received little attention in the context of human research ethics. We carried out an empirical study to gain insight into uncertainty by asking IRB/REC members about confidence in their risk assessments immediately after discussion of new protocols under review...
May 1, 2017: Journal of Empirical Research on Human Research Ethics: JERHRE
https://www.readbyqxmd.com/read/28557638/essentials-in-return-to-work-issues-a-tale-of-two-shoulders
#16
Candace L Sandal
Musculoskeletal disorders are common in the workplace and often respond to first-aid treatment. Worker education combined with precise management of precautionary restrictions by occupational health nurses can decrease employees' recovery time and lower risk of complications.
June 2017: Workplace Health & Safety
https://www.readbyqxmd.com/read/28557582/surgeon-performance-predicts-early-continence-after-robotic-assisted-radical-prostatectomy
#17
Mitchell G Goldenberg, S Larry Goldenberg, Teodor P Grantcharov
INTRODUCTION: There is limited, yet compelling evidence supporting the role of surgeon technical skill in influencing patient outcomes. To date, this concept has been underexplored in urologic surgery. We hypothesized that a surgeon's technical performance plays a role in predicting an early return to continence after robotic-assisted radical prostatectomy (RARP). METHODS: We conducted a retrospective, matched case-control analysis of prospectively collected unedited RARP endoscopic videos performed by a single surgeon...
May 30, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28549138/precautionary-bias
#18
Vasiliy V Vlassov
No abstract text is available yet for this article.
June 1, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/28544745/fs-laser-ablation-of-teeth-is-temperature-limited-and-provides-information-about-the-ablated-components
#19
Rebeca Ferraz de Menezes, Catherine Malinda Harvey, Marleny Elizabeth Márquez de Martínez Gerbi, Zachary J Smith, Dan Smith, Juan C Ivaldi, Alton Phillips, James W Chan, Sebastian Wachsmann-Hogiu
The goal of this work is to investigate the thermal effects of femtosecond laser (fs-laser) ablation for the removal of carious dental tissue. Additional studies identify different tooth tissues through femtosecond laser induced breakdown spectroscopy (fsLIBS) for the development of a feedback loop that could be utilized during ablation in a clinical setting. Scanning Election Microscope (SEM) images reveal that minimal morphological damages are incurred at repetition rates below the carbonization threshold of each tooth tissue...
May 24, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/28540396/-anaphylactic-reactions-to-vaccines-chicken-egg-allergy-and-the-influenza-h1n1-vaccination
#20
L Klimek, S Wicht-Langhammer, L von Bernus, C Thorn, D Cazan, O Pfaar, K Hörmann
BACKGROUND: Allergic reactions to influenza vaccinations are a well-known phenomenon; however, only a few published statistics give information on the risks. Patients with a chicken egg allergy must be particularly carefully handled during an influenza epidemic where vaccines produced using embryonated chicken eggs are primarily employed. METHODS: A selective literature review and analysis of the problem of allergic reactions to vaccinations was performed. RESULTS: The two most common relative contraindications among patients to be vaccinated are the presence of an egg allergy and a previous anaphylactic reaction to vaccination...
May 24, 2017: HNO
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