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https://www.readbyqxmd.com/read/29341236/induced-earthquakes-from-long-term-gas-extraction-in-groningen-the-netherlands-statistical-analysis-and-prognosis-for-acceptable-risk-regulation
#1
Charles Vlek
Recently, growing earthquake activity in the northeastern Netherlands has aroused considerable concern among the 600,000 provincial inhabitants. There, at 3 km deep, the rich Groningen gas field extends over 900 km2 and still contains about 600 of the original 2,800 billion cubic meters (bcm). Particularly after 2001, earthquakes have increased in number, magnitude (M, on the logarithmic Richter scale), and damage to numerous buildings. The man-made nature of extraction-induced earthquakes challenges static notions of risk, complicates formal risk assessment, and questions familiar conceptions of acceptable risk...
January 16, 2018: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/29336950/daratumumab-therapeutic-asset-biological-trap
#2
V Deneys, C Thiry, A Frelik, C Debry, B Martin, C Doyen
OBJECTIVES: Recently, daratumumab has been included in the therapeutic strategies for myeloma patients. This molecule is an antibody directed against CD38, strongly expressed on plasma cells. Nevertheless, as CD38 is also present on erythrocyte membrane, daratumumab interferes with immunohaematological tests, complicating the selection of compatible blood. METHODS: A total of 14 patients treated by daratumumab have been followed in our transfusion laboratory. Among them, 11 have been transfused...
January 11, 2018: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
https://www.readbyqxmd.com/read/29334942/poor-response-to-artesunate-treatment-in-two-patients-with-severe-malaria-on-the-thai-myanmar-border
#3
Aung Pyae Phyo, Kyaw Kyaw Win, Aung Myint Thu, Lei Lei Swe, Htike Htike, Candy Beau, Kanlaya Sriprawat, Markus Winterberg, Stephane Proux, Mallika Imwong, Elizabeth A Ashley, Francois Nosten
BACKGROUND: Malaria has declined dramatically along the Thai-Myanmar border in recent years due to malaria control and elimination programmes. However, at the same time, artemisinin resistance has spread, raising concerns about the efficacy of parenteral artesunate for the treatment of severe malaria. CASE PRESENTATION: In November 2015 and April 2017, two patients were treated for severe malaria with parenteral artesunate. Quinine was added within 24 h due to an initial poor response to treatment...
January 15, 2018: Malaria Journal
https://www.readbyqxmd.com/read/29333409/human-parvovirus-b19-and-parvovirus-4-among-iranian-patients-with-hemophilia
#4
Davod Javanmard, Masood Ziaee, Hadi Ghaffari, Mohammad Hasan Namaei, Ahmad Tavakoli, Hamidreza Mollaei, Mohsen Moghoofei, Helya Sadat Mortazavi, Seyed Hamidreza Monavari
Background: Human parvovirus B19 (B19V) is one of the smallest DNA viruses and shows great resistance to most disinfectants. Therefore, it is one of the common contaminant pathogens present in blood and plasma products. Parvovirus 4 (PARV4) is a newly identified parvovirus, which is also prevalent in parenteral transmission. In this study, we aimed to evaluate the prevalence of B19V and PARV4 DNA among patients with hemophilia in Birjand County in eastern Iran. Methods: This was a cross-sectional epidemiological study comprising nearly all people with hemophilia in this region...
December 2017: Blood Research
https://www.readbyqxmd.com/read/29323610/the-debate-about-electronic-cigarettes-harm-minimization-or-the-precautionary-principle
#5
Lawrence W Green, Jonathan E Fielding, Ross C Brownson
Two contrasting reviews (authored by Abrams et al. and Glanz & Bareham) in this volume have reached opposing conclusions on the effects of electronic cigarettes in a debate that is dividing the scientific and professional communities that have devoted careers to controlling the manufacture, advertising, sale, and use of combustible cigarettes. The research on the types, degree, and extent of harm from e-cigarettes is far from complete and, together with trends in teenage smoking and vaping, has raised new questions and prospects about the potential benefits that the new electronic products offer smokers of combustible cigarettes in quitting or at least cutting back on the known risks associated with the traditional forms of smoking...
January 11, 2018: Annual Review of Public Health
https://www.readbyqxmd.com/read/29310764/reducing-environmental-allergic-triggers-policy-issues
#6
Stuart L Abramson
The implementation of policies to reduce environmental allergic triggers can be an important adjunct to optimal patient care for allergic rhinitis and allergic asthma. Policies at the local level in schools and other public as well as private buildings can make an impact on disease morbidity. Occupational exposures for allergens have not yet been met with the same rigorous policy standards applied for exposures to toxicants by Occupational Safety and Health Administration. Further benefit may be obtained through policies by local, county, state, and national governments, and possibly through international cooperative agreements...
January 2018: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29310508/comments-on-climate-change-and-public-health-a-small-frame-obscures-the-picture
#7
Francesco Chirico
Energy strategies to reduce elevated CO2 levels have costs and benefit both known and unknown, and available scientific evidence will not be effective if we ignore relevant information about the costs. Indeed, some economists have attempted to place the analysis of global climate change in the context of cost-benefit analysis, by weighing the consequences of the projected increase in carbon emissions versus the cost of current policy actions to stabilize or even reduce CO2 emissions. However, an immediate policy action is required to reduce CO2 and other human-induced greenhouse gas emissions in the coming decades, accordingly with the "precautionary principle...
January 1, 2018: New Solutions: a Journal of Environmental and Occupational Health Policy: NS
https://www.readbyqxmd.com/read/29289281/mesoporous-carbon-nanomaterials-induced-pulmonary-surfactant-inhibition-cytotoxicity-inflammation-and-lung-fibrosis
#8
Yunan Chen, Yi Yang, Bolong Xu, Shunhao Wang, Bin Li, Juan Ma, Jie Gao, Yi Y Zuo, Sijin Liu
Environmental exposure and health risk upon engineered nanomaterials are increasingly concerned. The family of mesoporous carbon nanomaterials (MCNs) is a rising star in nanotechnology for multidisciplinary research with versatile applications in electronics, energy and gas storage, and biomedicine. Meanwhile, there is mounting concern on their environmental health risks due to the growing production and usage of MCNs. The lung is the primary site for particle invasion under environmental exposure to nanomaterials...
December 2017: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/29288073/fish-viruses-stored-in-rnalater-can-remain-infectious-and-even-be-temporarily-protected-from-inactivation-by-heat-or-by-tissue-homogenates
#9
Phuc H Pham, Bibi S H Sokeechand, Kyle A Garver, Ginny Jones, John S Lumsden, Niels C Bols
RNAlater is a commonly used transport and storage solution for samples collected for fish health investigations, particularly those potentially involving viruses. However, the infectivity of fish viruses after storage in RNAlater have not been determined. Nevertheless, knowledge of pathogen infectivity of preserved samples is crucial for ensuring safe transport and storage protocols. Therefore, the infectivity of three fish RNA viruses in RNAlater was examined at four temperatures: -80 °C, 4 °C, room temperature (RT, approximately 22 °C) and 37 °C...
December 26, 2017: Journal of Virological Methods
https://www.readbyqxmd.com/read/29284346/safe-handling-of-monoclonal-antibodies-too-large-to-be-hazardous
#10
Mário L de Lemos, Nadine Badry, Victoria Kletas, Joan Fabbro, Amber Tew
It has been argued that the larger molecular weight of hazardous monoclonal antibodies may prevent their dermal absorption via occupational exposure. However, this assertion does not seem to be supported by direct evidence. Although the larger molecular weight may render monoclonal antibodies less probable to achieve therapeutic systemic level through dermal absorption, the concern in occupational health is whether these drugs can possibly attain a detectable level through repeated dermal exposure. Currently, there is no direct evidence to support a particular molecular weight above which a drug cannot achieve a detectable level following repeated occupational exposure...
January 1, 2017: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29276412/association-between-coffee-or-caffeine-consumption-and-fecundity-and-fertility-a-systematic-review-and-dose-response-meta-analysis
#11
REVIEW
Julie Lyngsø, Cecilia Høst Ramlau-Hansen, Bjørn Bay, Hans Jakob Ingerslev, Adam Hulman, Ulrik Schiøler Kesmodel
Objective: The aim was to investigate whether coffee or caffeine consumption is associated with reproductive endpoints among women with natural fertility (ie, time to pregnancy [TTP] and spontaneous abortion [SAB]) and among women in fertility treatment (ie, clinical pregnancy rate or live birth rate). Design: This study was a systematic review and dose-response meta-analysis including data from case-control and cohort studies. Methods: An extensive literature search was conducted in MEDLINE and Embase, with no time and language restrictions...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/29236757/high-genetic-structure-and-low-mitochondrial-diversity-in-bottlenose-dolphins-of-the-archipelago-of-bocas-del-toro-panama-a-population-at-risk
#12
Dalia C Barragán-Barrera, Laura J May-Collado, Gabriela Tezanos-Pinto, Valentina Islas-Villanueva, Camilo A Correa-Cárdenas, Susana Caballero
The current conservation status of the bottlenose dolphin (Tursiops truncatus) under the IUCN is 'least concern'. However, in the Caribbean, small and localized populations of the 'inshore form' may be at higher risk of extinction than the 'worldwide distributed form' due to a combination of factors including small population size, high site fidelity, genetic isolation, and range overlap with human activities. Here, we study the population genetic structure of bottlenose dolphins from the Archipelago of Bocas del Toro in Panama...
2017: PloS One
https://www.readbyqxmd.com/read/29230648/risk-perception-of-aquatic-pollution-originated-from-chemical-industry-clusters-in-the-coastal-area-of-jiangsu-province-china
#13
Hong Yao, Bo Liu, Zhen You, Li Zhao
According to "the Layout Scheme of the Chemical Industry in Jiangsu Province From 2016 to 2030" and "the Development Planning in the Coastal Area of Jiangsu Province, China," several chemical industry clusters will be located in the coastal area of Jiangsu province, China, and the risk of surface water pollution will be inevitably higher in the densely populated region. To get to know the risk acceptance level of the residents near the clusters, public perception was analyzed from the five risk factors: the basic knowledge about the pollution, the negative effects on aquatic environment imposed by the clusters, the positive effects brought by the clusters, the trust of controlling aquatic pollution, and the acceptance of the clusters...
December 11, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29225809/venous-air-embolism-related-to-the-use-of-central-catheters-revisited-with-emphasis-on-dialysis-catheters
#14
REVIEW
Steve Siu-Man Wong, Hau C Kwaan, Todd S Ing
Venous air embolism is a dreaded condition particularly relevant to the field of nephrology. In the face of a favourable, air-to-blood pressure gradient and an abnormal communication between the atmosphere and the veins, air entrance into the circulation is common and can bring about venous air embolism. These air emboli can migrate to different areas through three major routes: pulmonary circulation, paradoxical embolism and retrograde ascension to the cerebral venous system. The frequent undesirable outcome of this disease entity, despite timely and aggressive treatment, signifies the importance of understanding the underlying pathophysiological mechanism and of the implementation of various preventive measures...
December 2017: Clinical Kidney Journal
https://www.readbyqxmd.com/read/29214499/microbial-degradation-of-forensic-samples-of-biological-origin-potential-threat-to-human-dna-typing
#15
REVIEW
Hirak Ranjan Dash, Surajit Das
Forensic biology is a sub-discipline of biological science with an amalgam of other branches of science used in the criminal justice system. Any nucleated cell/tissue harbouring DNA, either live or dead, can be used as forensic exhibits, a source of investigation through DNA typing. These biological materials of human origin are rich source of proteins, carbohydrates, lipids, trace elements as well as water and, thus, provide a virtuous milieu for the growth of microbes. The obstinate microbial growth augments the degradation process and is amplified with the passage of time and improper storage of the biological materials...
December 6, 2017: Molecular Biotechnology
https://www.readbyqxmd.com/read/29214149/measurements-of-radiofrequency-radiation-with-a-body-borne-exposimeter-in-swedish-schools-with-wi-fi
#16
Lena K Hedendahl, Michael Carlberg, Tarmo Koppel, Lennart Hardell
Introduction: Wireless access to the Internet is now commonly used in schools. Many schools give each student their own laptop and utilize the laptops and wireless fidelity (Wi-Fi) connection for educational purposes. Most children also bring their own mobile phones to school. Since children are obliged by law to attend school, a safe environment is important. Lately, it has been discussed if radiofrequency (RF) radiation can have long-term adverse effects on children's health. Method: This study conducted exposimetric measurements in schools to assess RF emissions in the classroom by measuring the teachers' RF exposure in order to approximate the children's exposure...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/29202914/integrating-allergen-analysis-within-a-risk-assessment-framework-approaches-to-development-of-targeted-mass-spectrometry-methods-for-allergen-detection-and-quantification-in-the-ifaam-project
#17
Chiara Nitride, Victoria Lee, Ivona Baricevic-Jones, Karine Adel-Patient, Sabine Baumgartner, E N Clare Mills
Allergen analysis is central to implementing and monitoring food allergen risk assessment and management processes by the food industry, but current methods for the determination of allergens in foods give highly variable results. The European Union-funded "Integrated Approaches to Food Allergen and Allergy Risk Management" (iFAAM) project has been working to address gaps in knowledge regarding food allergen management and analysis, including the development of novel MS and immuno-based allergen determination methods...
December 5, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/29202911/the-allergen-bureau-vital-program
#18
Simon Brooke Taylor, Georgina Christensen, Kirsten Grinter, Robin Sherlock, Lisa Warren
This paper sets out the role of the Allergen Bureau and the Voluntary Incidental Trace Allergen Labelling (VITAL) Program from its origin in 2007 to its current iteration, VITAL 2. Herewith are outlined the scientific principles that support the program; the program's application in the food chain; and the benefits of the program's use to the food industry, clinicians, and the allergic consumer. VITAL was developed by the Australian and New Zealand food industry in consultation with multiple stakeholders, including consumer organizations, industry bodies, regulators, and retailers, to provide a standardized, science-based risk assessment process for the investigation of the potential presence of food allergens due to cross-contact and to determine whether, for cases in which the allergen is unable to be removed or controlled consistently, precautionary statements are required...
December 5, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/29202907/challenges-and-path-forward-on-mandatory-allergen-labeling-and-voluntary-precautionary-allergen-labeling-for-a-global-company
#19
Jupiter Yeung, Marie-Claude Robert
For food manufacturers, the label on a food package is a tool meant to alert consumers to the presence of specific allergens, allowing consumers to make informed decisions and not unnecessarily limit their food choices. Mandatory allergen labeling is used when the allergen is an intentionally added ingredient, whereas voluntary allergen labeling is used when the presence of the allergen is unintentional and may be in the finished product as a result of cross-contact. In a globalized economy, ensuring food safety is a growing challenge for manufacturers...
December 5, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/29202906/managing-food-allergens-in-the-u-k-retail-supply-chain
#20
Michael J Walker, M Hazel Gowland, John Points
The U.K. food and grocery market is highly significant financially and dominated by 10 retailers within a regulated and extremely economically competitive environment. We summarize the approach of U.K. retailers to allergen risk assessment (RA) and risk management (RM) within the U.K. legal framework and explore public visibility of retailers' allergen policies. RA and RM of allergens appear effective in curtailing retail-triggered severe food allergy reactions. However, allergen recalls remain high, precautionary allergen labeling (PAL) remains an area of confusion, and there is no consistent Web-based provision of information for consumers who have allergies...
December 5, 2017: Journal of AOAC International
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