J A Ajani, P F Mansfield, C H Crane, T T Wu, S Lunagomez, P M Lynch, N Janjan, B Feig, J Faust, J C Yao, R Nivers, J Morris, P W Pisters
PURPOSE: Preoperative chemoradiotherapy may increase the R0 (curative) resection rate, overall survival (OS) duration, and disease-free survival (DFS) duration. We evaluated paclitaxel-based induction chemotherapy and chemoradiotherapy in patients with localized gastric or gastroesophageal adenocarcinoma to determine its feasibility, impact on the R0 resection rate, type of pathologic response, OS, and DFS. PATIENTS AND METHODS: Patients with operable, localized gastric, or gastroesophageal adenocarcinoma were eligible...
February 20, 2005: Journal of Clinical Oncology