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https://www.readbyqxmd.com/read/29417229/endoscopic-submucosal-dissection-for-early-gastric-cancer-on-the-lesser-curvature-in-upper-third-of-the-stomach-is-a-risk-factor-for-postoperative-delayed-gastric-emptying
#1
Tetsuya Yoshizaki, Daisuke Obata, Yasuhiro Aoki, Norihiro Okamoto, Hiroki Hashimura, Chise Kano, Megumi Matsushita, Atsushi Kanamori, Kei Matsumoto, Masahiro Tsujimae, Kenji Momose, Takaaki Eguchi, Shunsuke Okuyama, Hiroshi Yamashita, Mikio Fujita, Akihiko Okada
BACKGROUND: Advances in Endoscopic submucosal dissection (ESD) technology have established ESD for early gastric cancer as a safe and stable technique. However, ESD may induce delayed gastric emptying and the cause of food residue retention in the stomach after ESD is not clear. This study aimed to clarify risk factors for delayed gastric emptying with food retention after gastric ESD. METHODS: We retrospectively examined for food residue in the stomach 1 week after ESD was performed for early gastric carcinoma at Osaka Saiseikai Nakatsu Hospital from February 2008 to November 2016...
February 7, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29408916/investigation-of-single-and-synergic-effects-of-nlrc5-and-pd-l1-variants-on-the-risk-of-colorectal-cancer
#2
Calogerina Catalano, Miguel Inacio da Silva Filho, Christoph Frank, Katerina Jiraskova, Veronika Vymetalkova, Miroslav Levy, Vaclav Liska, Ondrej Vycital, Alessio Naccarati, Ludmila Vodickova, Kari Hemminki, Pavel Vodicka, Alexander N R Weber, Asta Försti
Constitutive activation of interferon signaling pathways has been reported in colorectal cancer (CRC), leading to a strong CD8+ T cell response through stimulation of NLRC5 expression. Primed CD8+ T cell expansion, however, may be negatively regulated by PD-L1 expression. Additionally, aberrant PD-L1 expression enables cancer cells to escape the immune attack. Our study aimed to select potential regulatory variants in the NLRC5 and PD-L1 genes by using several online in silico tools, such as UCSC browser, HaploReg, Regulome DB, Gtex Portal, microRNA and transcription factor binding site prediction tools and to investigate their influence on CRC risk in a Czech cohort of 1424 CRC patients and 1114 healthy controls...
2018: PloS One
https://www.readbyqxmd.com/read/29385044/the-influence-of-supportive-and-ethical-work-environments-on-work-related-accidents-injuries-and-serious-psychological-distress-among-hospital-nurses
#3
Maki Tei-Tominaga, Miharu Nakanishi
The healthcare industry in Japan has experienced many cases of work-related injuries, accidents, and workers' compensation claims because of mental illness. This study examined the influence of supportive and ethical work environments on work-related accidents, injuries, and serious psychological distress among hospital nurses. Self-reported questionnaires were distributed to nurses (n = 1114) from 11 hospitals. Valid responses (n = 822, 93% women, mean age = 38.49 ± 10.09 years) were used for analyses. The questionnaire included items addressing basic attributes, work and organizational characteristics, social capital and ethical climate at the workplace, psychological distress, and experience of work-related accidents or injuries in the last half year...
January 31, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29357921/relating-process-evaluation-measures-to-complex-intervention-outcomes-findings-from-the-pace-up-primary-care-pedometer-based-walking-trial
#4
Cheryl Furness, Emma Howard, Elizabeth Limb, Derek G Cook, Sally Kerry, Charlotte Wahlich, Christina Victor, Ulf Ekelund, Steve Iliffe, Michael Ussher, Peter Whincup, Julia Fox-Rushby, Judith Ibison, Stephen DeWilde, Tess Harris
BACKGROUND: The PACE-UP trial demonstrated positive effects of a pedometer-based walking intervention on objective physical activity (PA) outcomes at three and 12 months in 45-75-year-old primary care patients, in postal and nurse-supported trial arms compared with controls. We explored associations between process evaluation measures and change in PA outcomes. METHODS: The MRC framework guided process evaluation. Three quantitative measures (nurse session attendance [dose delivered], PA diary completion [fidelity] and pedometer use [fidelity]) were selected as independent variables in multi-level models estimating intervention effectiveness on PA outcomes (changes in step-counts and time in moderate-to-vigorous PA [MVPA] levels in ≥ 10-min bouts)...
January 22, 2018: Trials
https://www.readbyqxmd.com/read/29334549/cost-effectiveness-of-alternative-strategies-for-provision-of-hiv-pre-exposure-prophylaxis-for-people-who-inject-drugs
#5
Rui Fu, Douglas K Owens, Margaret L Brandeau
BACKGROUND: Oral HIV pre-exposure prophylaxis (PrEP) has been recommended as a means of HIV prevention among people who inject drugs (PWID) but, at current prices, is unlikely to be cost-effective for all PWID. OBJECTIVE: To determine the cost-effectiveness of alternative strategies for enrolling PWID in PrEP. DESIGN: Dynamic network model that captures HIV transmission and progression among PWID in a representative US urban center. OUTCOME MEASURES: HIV infections averted, discounted costs and quality-adjusted life-years (QALYs), and incremental cost-effectiveness ratios (ICERs)...
January 13, 2018: AIDS
https://www.readbyqxmd.com/read/29329029/corrigendum-to-pharmacological-profile-of-dexketoprofen-in-orofacial-pain-pharmacol-rep-68-6-2016-1111-1114
#6
Hugo F Miranda, Fernando Sierralta, Nicolás Aranda, Viviana Noriega, Juan Carlos Prieto
No abstract text is available yet for this article.
January 9, 2018: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/29322794/integrated-analysis-of-the-rna-seq-data-of-liver-hepatocellular-carcinoma
#7
H Xue, L Luo, Y T Yao, L L Wei, S P Deng, X L Huang
The present study aimed to explore the genetic changes involved in the liver hepatocellular carcinoma (HCC) development. The RNA-Seq data of 212 HCC tissue samples and 50 normal tissue samples were downloaded using TCGA-Assembler. A total of 4 subgroups were obtained, and 4167, 6279, 5379, and 2548 DEGs were screened in group 1, group 2, group 3, and group 4, respectively. Enrichment analysis found that cell cycle, metabolism, and translation related terms were the most significantly changed functions and pathways...
2018: Neoplasma
https://www.readbyqxmd.com/read/29250480/cultural-competence-in-working-with-the-arab-australian-community-a-conceptual-review-and-the-experience-of-the-arab-council-australia-aca-gambling-help-counselling-service
#8
Randa Mazbouh-Moussa, Keis Ohtsuka
Although Culturally And Linguistically Diverse (CALD) communities participate less in gambling than the general population, those who gamble are more likely to show signs of disordered gambling (Moore and Ohtsuka International Gambling Studies, 1, 87-101, 2001; Raylu and Oei Clinical Psychology Review, 23, 1087-1114, 2004; Yamine and Thomas The impact of gaming on specific cultural groups, Victorian Casino and Gaming Authority, Melbourne, 2000). Research data on gambling problems and interventions in the Arab Australian community are extremely scarce...
2017: Asian Journal of Gambling Issues and Public Health
https://www.readbyqxmd.com/read/29240922/prevalence-magnitude-and-correlates-of-hiv-1-genital-shedding-in-women-on-antiretroviral-therapy
#9
Caroline C King, Sascha R Ellington, Nicole L Davis, Robert W Coombs, Maria Pyra, Ting Hong, Nelly Mugo, Rena C Patel, Jairam R Lingappa, Jared M Baeten, Athena P Kourtis
Background: Genital human immunodeficiency virus (HIV) RNA shedding can continue despite HIV being undetectable in blood, and can be associated with transmission. Methods: We included African women on antiretroviral therapy (ART). Linear and generalized linear mixed models were used to compare the magnitude and prevalence of genital shedding, respectively, by time since ART initiation. Multivariable logistic regression with generalized estimating equations was used to assess predictors of genital shedding among women with undetectable plasma viral load (VL)...
December 12, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29239711/interval-breast-cancer-rates-and-histopathologic-tumor-characteristics-after-false-positive-findings-at-mammography-in-a-population-based-screening-program
#10
Solveig Hofvind, Silje Sagstad, Sofie Sebuødegård, Ying Chen, Marta Roman, Christoph I Lee
Purpose To compare rates and tumor characteristics of interval breast cancers (IBCs) detected after a negative versus false-positive screening among women participating in the Norwegian Breast Cancer Screening Program. Materials and Methods The Cancer Registry Regulation approved this retrospective study. Information about 423 445 women aged 49-71 years who underwent 789 481 full-field digital mammographic screening examinations during 2004-2012 was extracted from the Cancer Registry of Norway. Rates and odds ratios of IBC among women with a negative (the reference group) versus a false-positive screening were estimated by using logistic regression models adjusted for age at diagnosis and county of residence...
December 14, 2017: Radiology
https://www.readbyqxmd.com/read/29227273/-poisoning-by-psychopharmacological-drugs-in-azerbaijan-the-results-of-8-year-prospective-observation
#11
I Afandiyev, V Azizov
Acute poisoning of chemical etiology is a significant global public health problem. The aim of this study was the analysis of the toxicoepidemiological structure of psychopharmacological drugs poisoning in Azerbaijan. We collected and analyzed the data on all cases of acute poisoning by psychopharmacological drugs (codes of categories T42/T43 ICD-10) undergoing inpatient treatment at the Center of Clinical Toxicology in Baku, Azerbaijan in 2009-2016. The total number of patients with acute intoxication by psychopharmacological drugs was 3,413, which was 48...
November 2017: Georgian Medical News
https://www.readbyqxmd.com/read/29208861/etiology-of-early-renal-allograft-dysfunction-and-comparison-between-dysfunction-and-function-group-a-single-center-study
#12
K M Hadiuzzaman, S F Islam, M O Faroque, R M Hossain, M Munirunnessa, S I Selim, M Morshed
Over a period of two years thirty five renal allograft recipients & donors were evaluated to find out the aetiology of early renal allograft dysfunction, in the Department of Nephrology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh from March 2010 to February 2012. A comparison was made between dysfunction & functioning graft group. Mean age of recipients were (36.4±9.4) years, mean age of donors were (41.7±8.3) years, with a male and female ratio of 3:1. Fifty percent recipients showed one heliotype match, ninety percent recipients were anti CMV antibody IgG positive, few were anti CMV antibody IgM positive...
October 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29148842/erratum
#13
(no author information available yet)
Yao H, Lu H, Zhao H, et al. Open reduction assisted with an external fixator and internal fixation with calcaneal locking plate for intra-articular calcaneal fractures. Foot Ankle Int. 2017;38(10):1107-1114. (Original DOI: 10.1177/1071100717715908) The above article appeared with the incorrect corresponding author. The correct corresponding author is Huading Lu, PhD. The corrected corresponding author information is below: Corresponding Author: Huading Lu, PhD, Department of Orthopaedics, The Fifth Affiliated Hospital of Sun Yat-sen University, NO...
November 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/29134925/effects-of-ssri-exposure-on-hemorrhagic-complications-and-outcome-following-thrombolysis-in-ischemic-stroke
#14
Christoph Schellen, Julia Ferrari, Wilfried Lang, Marek Sykora
Background Selective serotonin reuptake inhibitors (SSRI) may interfere with platelet function, and pre-stroke SSRI treatment has been associated with increased hematoma volumes and mortality in hemorrhagic stroke patients. The effects of SSRI on the risk of hemorrhagic complications after thrombolysis in ischemic stroke patients are unclear. Aims To examine the effects of pre-stroke SSRI exposure on bleeding complications, functional outcome, and mortality following thrombolysis in ischemic stroke. Methods Data including standard demographic and clinical variables as well as baseline and follow-up stroke severity (measured by National Institutes of Health Stroke Score), functional outcome (measured by modified Rankin Scale) at 3 months, and mortality at 7 and 90 days were extracted from the Virtual International Stroke Trials Archive...
January 1, 2017: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/29107379/engineered-designer-biochar-for-the-removal-of-phosphate-in-water-and-wastewater
#15
Kumar Vikrant, Ki-Hyun Kim, Yong Sik Ok, Daniel C W Tsang, Yiu Fai Tsang, Balendu Shekhar Giri, Ram Sharan Singh
During the past decade, biochar has attracted immense scientific interest for agricultural and environmental applications. A broad range of biochars with advantageous properties (e.g., high surface area, flexible architecture, and high porosity) has been developed for pollution abatement. Nevertheless, biochar suffers from certain drawbacks (e.g., limited sorption capacity for anions and poor mechanical properties) that limit their practical applicability. This review focuses on recent advancements in biochar technology, especially with respect to its technical aspects, the variables associated with removing phosphates from water, and the challenges for such abatement...
October 26, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29092921/contrast-induced-acute-kidney-injury-and-mortality-in-st-elevation-myocardial-infarction-treated-with-primary-percutaneous-coronary-intervention
#16
Johanne Silvain, Lee S Nguyen, Vincent Spagnoli, Mathieu Kerneis, Paul Guedeney, Nicolas Vignolles, Kristel Cosker, Olivier Barthelemy, Claude Le Feuvre, Gérard Helft, Jean-Philippe Collet, Gilles Montalescot
OBJECTIVES: Contrast-induced acute kidney injury (CI-AKI) is a common and potentially severe complication in patients with ST elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI). There is no consensus on the best definition of CI-AKI to identify patients at risk of haemodialysis or death. The objective of this study was to assess the association of CI-AKI, using four definitions, on inhospital mortality, mortality or haemodialysis requirement over 1-year follow-up, in patients with STEMI treated with pPCI...
November 1, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29092898/patient-preference-and-choice-of-healthcare-providers-in-shanghai-china-a-cross-sectional-study
#17
Wenya Yu, Meina Li, Feng Ye, Chen Xue, Lulu Zhang
OBJECTIVES: This study aimed to assess patients' healthcare-seeking preferences in mild, chronic, and serious illness; identify influential factors; and examine the reasons underlying patients' healthcare-seeking preference. DESIGN: A retrospective study. SETTING: The study was conducted in 14 tertiary hospitals in Shanghai, China. PARTICIPANTS: Questionnaires were distributed to 1519 patients, and 1114 were completed and returned...
November 1, 2017: BMJ Open
https://www.readbyqxmd.com/read/29076974/on-the-role-of-illness-duration-and-nutrient-restriction-in-cholestatic-alterations-that-occur-during-critical-illness
#18
Marc Jenniskens, Fabian Güiza, Marlies Oorts, Sarah Vander Perre, Sarah Derde, Thomas Dufour, Steven Thiessen, Pieter Annaert, Greet Van den Berghe, Lies Langouche
BACKGROUND AND AIMS: Elevated markers of cholestasis are common in response to critical illness, and associated with adverse outcome. The role of illness duration and of nutrient restriction on underlying molecular pathways of such cholestatic responses have not been thoroughly investigated. METHODS: In a mouse model of surgery- and sepsis-induced critical illness, molecular pathways of cholestasis were investigated up to 7 days. To assess which changes are explained by illness-induced lack of feeding, nutrient-restricted healthy mice were studied and compared with ad libitum fed healthy mice...
October 25, 2017: Shock
https://www.readbyqxmd.com/read/29048369/effect-of-curcumin-on-the-diversity-of-gut-microbiota-in-ovariectomized-rats
#19
Zhiguo Zhang, Yanjing Chen, Lihua Xiang, Zhen Wang, Gary Guishan Xiao, Jingqing Hu
Curcumin has been proven to have a weight-loss effect in a menopausal rat model induced by ovariectomy. However, the effects of curcumin on gut microfloral communities of ovariectomized (OVX) rats remains unclear. Here, we used high-throughput 16S rDNA sequencing to explore the effects of curcumin on microbial diversity in the gut of OVX rats. Female Wistar rats were subjected to either ovariectomy or a sham operation (SHAM group). The OVX rats were treated with vehicle (OVX group) or curcumin (CUR group) by oral gavage...
October 19, 2017: Nutrients
https://www.readbyqxmd.com/read/28992258/risk-and-complications-of-venous-thromboembolism-in-dialysis-patients
#20
Amber O Molnar, Sarah E Bota, Eric McArthur, Ngan N Lam, Amit X Garg, Ron Wald, Deborah Zimmerman, Manish M Sood
Background: Contemporary data on venous thromboembolism (VTE) risk in dialysis patients are limited. Our objective was to determine the risk and complications of VTE among incident maintenance dialysis patients. Methods: We performed a retrospective cohort study using administrative databases. We included adult incident dialysis patients from 2004 to 2010 ( n  = 13 315). Dialysis patients were age- and sex-matched to individuals of the general population using a 1:4 ratio ( n  = 53 260)...
July 13, 2017: Nephrology, Dialysis, Transplantation
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