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https://www.readbyqxmd.com/read/29660923/haemochromatosis-pathophysiology-and-the-red-blood-cell1
#1
Kieran J Richardson, Antony P McNamee, Michael J Simmonds
Haemochromatosis remains the most prevalent genetic disorder of Caucasian populations in Australia and the United States, occurring in ∼1 of 200 individuals and having a carrier frequency of 10-14%. Hereditary haemochromatosis is an autosomal recessive condition, that is phenotypically characterised by a gradual accumulation of iron, above and beyond that required for biological function. Once the binding capacity of iron carriers reaches saturation, the highly reactive free iron generates radicals that may lead to widespread cellular dysfunction...
April 7, 2018: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/29657501/evaluation-of-bloodletting-cupping-therapy-in-the-management-of-hypertension
#2
Moawia M Al-Tabakha, Farah Tariq Sameer, Mai Hafiz Saeed, Rahaf Montaser Batran, Nada Tarek Abouhegazy, Alaa A Farajallah
Background: Bloodletting cupping therapy (Hijama) is a traditional alternative medicine practiced in different cultures. Claims about the therapeutic efficacy of Hijama in hypertension are contradictory. The aim of this project was to determine if Hijama therapy is beneficial in the treatment of patients with hypertension. Materials and Methods: In this retrospective study, 60 files for patients treated for hypertension, aged 40-60 years and whose systolic blood pressure (SBP) is at least 140mm Hg, were used...
January 2018: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29602653/the-use-of-medicinal-leeches-for-the-treatment-of-venous-congestion-in-replanted-or-revascularized-digits
#3
Amir Arami, Shelly Gurevitz, Ram Palti, Shay Menachem, Mina Berelowitz, Batia Yaffe
PURPOSE: A noteworthy cause of failure in digital replantation is venous insufficiency. External bloodletting with medicinal leeches is a common treatment for venous insufficiency after distal digital replantations. The objective of this study was to evaluate the salvage rate of digits replanted proximal to the distal interphalangeal (DIP) joint that were treated with medicinal leeches for venous congestion. METHODS: We retrospectively reviewed the charts of patients with complete or incomplete digit amputation admitted between January, 2008 and April, 2014...
March 27, 2018: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29593463/young-blood-rejuvenates-old-bodies-a-call-for-reflection-when-moving-from-mice-to-men
#4
Bjørn Hofmann
Connecting the circulatory system of old and young mice (parabiosis) is documented to have rejuvenating effects on cells, tissues, organs, and functions. A wide range of benefits are envisioned. Blood-based rejuvenation can come to totally change population health and aging. The first blood rejuvenation studies on humans with Alzheimer's disease have started. It puts blood at the center of therapy and revitalizes the historical line of humoral pathology from Hippocrates and Harvey, creating a new type of 'bloodletting...
January 2018: Transfusion Medicine and Hemotherapy
https://www.readbyqxmd.com/read/29519276/-effects-of-acute-respiratory-distress-syndrome-induced-by-endotoxin-on-the-right-ventricular-function-in-rats
#5
Shaolei Ma, Yujie Wang, Xiangrong Zuo, Jing Yao, Quan Cao
OBJECTIVE: To explore the effect of acute respiratory distress syndrome (ARDS) induced by endotoxin on the right ventricular function in rats. METHODS: Sixty male Sprague-Dawley (SD) rats were randomly divided into normal saline (NS) control group and lipopolysaccharide (LPS) model group with 30 rats in each group. The rat model of ARDS was reproduced by intratracheal instillation of LPS 10 mg/kg after tracheotomy, and the rats in NS control group was intratracheally given the same volume of NS instead of LPS...
March 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29518637/-blood-letting-self-phlebotomy-in-injecting-anabolic-androgenic-steroids-within-performance-and-image-enhancing-drug-pied-culture
#6
Rebekah Brennan, John Wells, Marie Claire Van Hout
BACKGROUND: New evidence with regard to a previously undocumented practice - self phlebotomy, known as 'bloodletting' - incontemporary injecting performance and image enhancing drug (PIED) culture is the subject of this paper. While self phlebotomy has been evidenced in psychiatric patients previously, it was performed here in people who inject AAS as a self directed health care procedure. METHODS: Data was collected from five publicly accessible internet discussion forums and coded using NVivo software...
March 5, 2018: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29381990/a-case-study-of-ramsay-hunt-syndrome-in-conjunction-with-cranial-polyneuritis
#7
Ru-Wen Zheng, Di Liu, Tay E Eric, Yan-Zhe Ning, Lu-Lu Chen, Hui Hu, Yi Ren
RATIONALE: Ramsay Hunt syndrome in conjunction with cranial polyneuritis is not extensively documented, and is very easily misdiagnosed. PATIENT CONCERNS: A case of a 53-year-old male with Ramsay Hunt syndrome in conjunction with cranial polyneuritis is presented with early symptoms of vertigo, cephalalgia, and facial palsy, followed by zoster oticus 10 days later. DIAGNOSES: Diagnosis was challenging as this condition presents with multiple neuropathies, and attempting to diagnose based on clinical symptoms was often misleading...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29354940/-ji-laixi-s-experience-of-acupuncture-and-moxibustion-for-knee-osteoarthritis
#8
Shangqing Li, Aiai Dong, Zhijun Hu, Xinzhi Zhu
In theory of TCM, the root cause of knee osteoarthritis ( xibi ) is the deficiency of liver and kidney, while the symptoms are involved with multiple damages of muscles, tendons and joints. The exogenous evil of wind, coldness, dampness and heat as well as the blood stasis usually block the meridians and collaterals, which cause the knee osteoarthritis. Professor JI Laixi selects acupoints based on syndrome differentiation, and treats both root cause and symptoms. He attaches importance to the ashi points, and takes pain as acupoints...
January 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29332103/proteomic-effects-of-wet-cupping-al-hijamah
#9
Amer A Almaiman
Wet cupping (Al-hijamah) is a therapeutic technique practiced worldwide as a part of the Unani system of medicine. It involves bloodletting from acupoints on a patient's skin to produce a therapeutic outcome. A thorough review of research articles on wet cupping with relevance to proteomics field that are indexed by Google Scholar, PubMed, and/or Science Direct databases was performed. Eight original research articles were summarized in this paper. Overall, wet cupping did not have a significant effect on C-reactive protein, Hsp-27, sister chromatid exchanges, and cell replication index...
January 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29235301/-advantages-and-problems-of-traditional-chinese-medicine-in-treatment-of-acute-pharyngitis
#10
Xia Zhang, Yan-Ming Xie, Guang-Xi Li, Yang Gao, Yuan-Chen Zhao, Jing-Jing Tang, Xiao-Yan Yao, Meng Li
This paper systematically studies relevant literatures at home and abroad in recent years. China National Knowledge Internet (CNKI) was used to collect the literatures for acute pharyngitis treated with traditional Chinese medicine from January 1, 2006, to December 31, 2016, and the bibliometric method was employed for statistical analysis. A total of 493 papers were preliminarily selected. According to the inclusion criteria and exclusion criteria, 182 eligible articles were selected. According to the evaluation and analysis of the literatures, the Guidelines for Clinical Research of New Drugs is currently used as the common standards for the diagnosis and treatment of acute pharyngitis; Chinese patent medicines are the main traditional Chinese medicine for treating this disease; Decoctions for treatment of this disease include Lonicerae Japonicae Flos, Scutellariae Radix, Platycodonis Radix, Forsythiae Fructus, Glycyrrhizae Radix et Rhizoma, Scrophdlariae Radix, Isatidis Radix, and Ophiopogonis Radix; The bloodletting puncture is the common external therapy...
October 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29231878/greek-medicine-practice-at-ancient-rome-the-physician-molecularist-asclepiades
#11
Luigi Santacroce, Lucrezia Bottalico, Ioannis Alexandros Charitos
Background: In the pre-Hellenistic period, the concept of medicine was not well-defined. Usually, a disease was considered as a divine punishment and its treatment was devolved to the priests who asked for healing from the divinities. The only job that could be compared to medical practice was a kind of itinerant medicine, derived from the Egyptian therapeutic tradition based only on practical experience and performed by people that knew a number of remedies, mostly vegetable, but without any theoretical bases about the possible mechanisms of action...
December 12, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/29231598/-analysis-on-the-laws-of-acupoint-selection-and-therapeutic-operations-with-acupuncture-based-on-the-characteristics-of-postherpetic-neuralgia
#12
Lei Wang, Qingchen Zhou, Hongfang Tian, Jiping Zhao
Postherpetic neuralgia is manifested as drastic lingering pain, which seriously impacts the survival quality of patient. In the paper, focusing on the time of postherpetic neuralgia and in association with the characteristics of symptoms such as the location and nature of pain and skin lesion, the etiology, location of sickness, nature of sickness and pathogenesis were differentiated, and the laws of acupoint selection and therapeutic operations were explored in the treatment with acupuncture. Regarding the apparent pain at night, especially during 23:00 to 3:00, Ashi points (Extra) and Jiaji (EX-B 2) were selected in terms of location differentiation...
April 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29115659/application-of-pulsed-arterial-resuscitation-in-a-rabbit-model-of-hemorrhagic-shock
#13
Wendong Sun, Zhihui Shao, Haisong Xu, Wusi Qiu, Jiahua Sun
BACKGROUND: Hemorrhagic shock is characterized by tissue hypoperfusion caused by a sharp reduction in the effective circulating volume of blood. The key to successful resuscitation lies in eliminating the shock as soon as possible while simultaneously restoring blood perfusion to vital organs. We present the applicability of pulsed arterial blood reinfusion for resuscitation of hemorrhagic shock. METHODS: Sixty rabbits were randomly assigned to resuscitation and control groups...
November 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/29101207/ferroportin-disease-pathogenesis-diagnosis-and-treatment
#14
REVIEW
Antonello Pietrangelo
Ferroportin Disease (FD) is an autosomal dominant hereditary iron loading disorder associated with heterozygote mutations of the ferroportin-1 ( FPN ) gene. It represents one of the commonest causes of genetic hyperferritinemia, regardless of ethnicity. FPN1 transfers iron from the intestine, macrophages and placenta into the bloodstream. In FD, loss-of-function mutations of FPN1 limit but do not impair iron export in enterocytes, but they do severely affect iron transfer in macrophages. This leads to progressive and preferential iron trapping in tissue macrophages, reduced iron release to serum transferrin (i...
December 2017: Haematologica
https://www.readbyqxmd.com/read/29072006/-rule-of-clinical-application-of-auricular-acupuncture-based-on-data-mining
#15
REVIEW
Na Bao, Qiong Wang, Yan-Hui Sun, Jing Shi, Xiao-Feng Li, Jing Xu, Hai-Jiao Xing, Xuan-Ping Zhang, Xin Zhang, Yu-Zhu Du, Jun-Lei Li, Qing-Qing Yang, Xin-Xin Feng, Chun-Sheng Jia, Jian-Ling Wang
OBJECTIVE: To explore the rule of clinical application of auricular acupuncture therapy by data mining in order to guide clinical practice. METHODS: The data base about single auricular acupuncture therapy for different clinical diseases was established by collection, sorting, screening, recording, collation, data extraction, statistic analysis on data samples from journals, academic theses dissertations published in near 60 years. The application rules of auricular therapy including its predominant diseases, stimulus modality, therapeutic effect, and angle of needling were summarized by data mining technique...
February 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/28954368/-textual-research-on-p-t-1061-a-tibetan-veterinary-medical-scroll-fragment-of-dunhuang-literature-preserved-in-france
#16
Y H Liu, G Yang, X D Hu
P. t.1061 preserved at the Manuscripts Department of the Bibiothèque Nationle de France, is a Dunhuang Tibetan veterinary medical manuscript that focuses on the surgical therapy of equine rhinopathy. The method of blowing a small quantity of ammonium chloride through a bamboo tube to treat horse nasal sinus diseases was described in the original scroll; if not effective, burn with a proper cauterization apparatus; if still ineffective, prick with a fine bloodletting needle; if still not effective, operate frontal trephination...
July 28, 2017: Zhonghua Yi Shi za Zhi, Chinese Journal of Medical History
https://www.readbyqxmd.com/read/28950851/the-ameliorative-effect-of-bloodletting-puncture-at-hand-twelve-jing-well-points-on-cerebral-edema-induced-by-permanent-middle-cerebral-ischemia-via-protecting-the-tight-junctions-of-the-blood-brain-barrier
#17
RANDOMIZED CONTROLLED TRIAL
Nannan Yu, Zhenguo Wang, Yucen Chen, Juntao Yang, Xuan Lu, Yi Guo, Zelin Chen, Zhifang Xu
BACKGROUND: Cerebral edema, erupting simultaneously with severe ischemic stroke, might lead to increased intracranial pressure, cerebral herniation, and ultimately death. Studies conducted previously by our team have demonstrated the fact that bloodletting puncture at hand twelve Jing-well points (HTWP) could alleviate cerebral edema, which mainly results from the disruption of blood-brain barrier (BBB). The study, therefore, was first designed to demonstrate whether BBB-protection serves an important role in the edema-relief effect of HTWP bloodletting, based on which to research the molecular mechanism underlying...
September 26, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28741249/ambroise-par%C3%A3-1510-1590-on-the-diagnosis-and-treatment-of-shoulder-dislocations
#18
REVIEW
Konstantinos Markatos, Marianna Karamanou, Gerasimos Tsourouflis, Georgios Androutsos, Andreas F Mavrogenis
AIM OF STUDY: This article aims to summarize the treatment methods for shoulder dislocations supported by Ambroise Paré, and his clinical and academic contribution to this subject. INTRODUCTION: Ambroise Paré (1510-1590) was one of the most prominent surgeons of his time, and one of the most significant innovators of the Renaissance in the fields of military operation, bandages, wound healing, bloodletting, close blood vessels techniques and cesarean section. For many, he is considered "the Father of Modern Surgery"...
January 2018: International Orthopaedics
https://www.readbyqxmd.com/read/28675198/the-bloody-moloch-osler-and-van-helmont-on-bloodletting
#19
I M Donaldson
In a passage on the treatment of pneumonia, Osler quoted van Helmont's remark that 'a bloody Moloch presides in the chairs of medicine'. This paper explores Helmont's use of 'Moloch' as a term of abuse against the bloodletting of traditional Galenist physicians and his vigorous opposition to the use of bleeding in treating diseases. The possible reasons for Helmont's opposition to the practice of bloodletting are discussed, leading to the conclusion that it arose from his theories of the origin of diseases, reinforced by some observations of its malign effects on a patient who had been bled excessively...
June 2017: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/28513500/rescue-vitrectomy-with-blocked-artery-massage-and-bloodletting-for-branch-retinal-artery-occlusion
#20
Chun-Ju Lin, Cheng-Wen Su, Huan-Sheng Chen, Wen-Lu Chen, Jane-Ming Lin, Yi-Yu Tsai
A 61-year-old male suffered from sudden blurred vision and superior visual field defect oculus dexter. His vision was counting fingers at 20 cm. Fundoscopy demonstrated inferior pale retina and a large embolus located at the proximal inferior retinal artery. Branch retinal artery occlusion (BRAO) was diagnosed. Initial paracentesis, topical brimonidine tartrate, oral pentoxifylline, and hyperbaric oxygen therapy were performed but showed limited improvement. Hence, he received 25-gauge vitrectomy, artificial posterior vitreous detachment, blocked retinal artery massage, and bloodletting 5 days after onset...
April 2017: Indian Journal of Ophthalmology
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