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https://www.readbyqxmd.com/read/27923069/characterization-in-helicobacter-pylori-of-a-nickel-transporter-essential-for-colonization-that-was-acquired-during-evolution-by-gastric-helicobacter-species
#1
Frédéric Fischer, Marie Robbe-Saule, Evelyne Turlin, Francesco Mancuso, Valérie Michel, Pierre Richaud, Frédéric J Veyrier, Hilde De Reuse, Daniel Vinella
Metal acquisition is crucial for all cells and for the virulence of many bacterial pathogens. In particular, nickel is a virulence determinant for the human gastric pathogen Helicobacter pylori as it is the cofactor of two enzymes essential for in vivo colonization, urease and a [NiFe] hydrogenase. To import nickel despite its scarcity in the human body, H. pylori requires efficient uptake mechanisms that are only partially defined. Indeed, alternative ways of nickel entry were predicted to exist in addition to the well-described NixA permease...
December 2016: PLoS Pathogens
https://www.readbyqxmd.com/read/27922829/a-methodology-to-split-the-total-cumulative-hp-10-dose-into-the-hp-10-i-doses-received-during-various-procedures-performed-by-interventional-cardiologist
#2
Joanna Domienik
The methodology describing how to split the cumulative Hp(10) dose of interventional cardiologists into Hp(10) i doses received during procedures of various types based on procedure-specific ELDO coefficients and Hp(3) doses per procedure is presented. The appropriate equations for Hp(10) i (Hp(10) for procedure type i), depending on the number of various procedure types (i  =  1 … 4) performed by a particular physician, are derived. The methodology can be applied to whole-body doses measured on the lead apron and therefore can be used for optimisation of work practices in those catheterisation labs where routine dosimeter is worn above the apron...
December 6, 2016: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/27922660/combined-vision-and-wearable-sensors-based-system-for-movement-analysis-in-rehabilitation
#3
Sofija Spasojević, Tihomir V Ilić, Slađan Milanović, Veljko Potkonjak, Aleksandar Rodić, José Santos-Victor
BACKGROUND: Traditional rehabilitation sessions are often a slow, tedious, disempowering and non-motivational process, supported by clinical assessment tools, i.e. evaluation scales that are prone to subjective rating and imprecise interpretation of patient's performance. Poor patient motivation and insufficient accuracy are thus critical factors that can be improved by new sensing / processing technologies. OBJECTIVES: We aim to develop a portable and affordable system, suitable for home rehabilitation, which combines vision-based and wearable sensors...
December 6, 2016: Methods of Information in Medicine
https://www.readbyqxmd.com/read/27921424/-mind-as-an-immunomodulator
#4
Cyril Höschl, Jiří Horáček
Review paper highlights the connection between psyche and the bodys immune defense mechanisms and summarizes new findings on the relations between nervous and immune systems. The article also briefly describes the outcome of authors own original works on the relationship between infections and schizophrenia, and their notice about possible immunomodulatory effects of antipsychoticsKey words: antipsychotics - immunity - infection - inflammation - mind - pain - schizophrenia.
2016: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/27920880/conditional-electrical-stimulation-in-animal-and-human-models-for-neurogenic-bladder-working-toward-a-neuroprosthesis
#5
C R Powell
Sacral neuromodulation has had a tremendous impact on the treatment of urinary incontinence and lower urinary tract symptoms for patients with neurologic conditions. This stimulation does not use real-time data from the body or input from the patient. Incorporating this is the goal of those pursuing a neuroprosthesis to enhance bladder function for these patients. Investigators have demonstrated the effectiveness of conditional (also called closed-loop) feedback in animal models as well as limited human studies...
December 2016: Current Bladder Dysfunction Reports
https://www.readbyqxmd.com/read/27920358/factors-affecting-counseling-services-in-social-service-structures-providing-support-to-women-who-are-victims-of-violence-a-qualitative-research-in-greece
#6
Katerina Flora, Anthi Argyroudi
This qualitative study examines the factors that affect counseling services in structures aimed to provide support to women who are victims of violence. What has created the need to investigate the above issues is the increase in events of violence against women in Greece, and the subsequent development of relevant support and accommodation structures. Despite the clinical experience accumulated, research data from Greece are incomplete. The main research question concerns the factors that affect counseling in violence counseling structures...
December 4, 2016: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/27919840/development-fabrication-and-evaluation-of-a-novel-biomimetic-human-breast-tissue-derived-breast-implant-surface
#7
S Barr, E W Hill, A Bayat
: Breast implant use has tripled in the last decade with over 320,000 breast implant based reconstructions and augmentations performed in the US per annum. Unfortunately a considerable number of women will experience capsular contracture, the irrepressible and disfiguring, tightening and hardening of the fibrous capsule that envelops the implant. Functionalising implant surfaces with biocompatible tissue-specific textures may improve in-vivo performance. A novel biomimetic breast implant is presented here with anti-inflammatory in-vitro abilities...
December 2, 2016: Acta Biomaterialia
https://www.readbyqxmd.com/read/27919517/centrifugal-partition-chromatography-a-preparative-tool-for-isolation-and-purification-of-xylindein-from-chlorociboria-aeruginosa
#8
Anukul Boonloed, Genevieve L Weber, Kelly M Ramzy, Veronica R Dias, Vincent T Remcho
A centrifugal partition chromatography (CPC) method was developed for the preparative-scale isolation and purification of xylindein from the wood-staining fungi, Chlorociboria aeruginosa. Xylindein, a blue-green pigment naturally secreted from the hyphae and fruiting bodies of the fungus, has great value in the decorative wood industry and textile coloration. Xylindein has great potential for use as a fluorescent labeling agent as well as in organic semiconductor applications. However, a primary limitation of xylindein is its poor solubility in most common HPLC solvents...
November 18, 2016: Journal of Chromatography. A
https://www.readbyqxmd.com/read/27917781/visualizing-a-natural-antibiotic-nanofactory
#9
T Martin Schmeing
Environmental samples are excellent sources of natural products that possess numerous kinds of therapeutic activities. One important family of natural products is the nonribosomal peptides, which includes penicillin, cyclosporin, viomycin and daptomycin (Cubicin). These peptides are made in bacteria or fungi by large enzymes called nonribosomal peptide synthetases (NRPS). NRPSs are true macromolecular machines or nanofactories, with modular assembly-line logic, a complex catalytic cycle, moving parts and many active sites...
December 1, 2016: Clinical and Investigative Medicine. Médecine Clinique et Experimentale
https://www.readbyqxmd.com/read/27917635/-raynaud-s-phenomenon
#10
Michal Tomčík
Raynaud's phenomenon (RP) is a very common sign which can usually be seen across all medical specialties. It is characterized by episodic color changes of acral parts of the body (palor, cyanosis, rubor) lasting from a few minutes to hours, which are usually triggered by cold temperature and/or stress. The primary RP occurs alone, without concomitant diseases, is usually benign and has favorable prognosis. Secondary RP occurs in a variety of diseases with a very variable progression and prognosis, mostly unfavorable one due to the development of ischemic tissue necrosis and gangrene...
2016: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/27917103/motor-imagery-during-action-observation-a-brief-review-of-evidence-theory-and-future-research-opportunities
#11
REVIEW
Daniel L Eaves, Martin Riach, Paul S Holmes, David J Wright
Motor imagery (MI) and action observation (AO) have traditionally been viewed as two separate techniques, which can both be used alongside physical practice to enhance motor learning and rehabilitation. Their independent use has largely been shown to be effective, and there is clear evidence that the two processes can elicit similar activity in the motor system. Building on these well-established findings, research has now turned to investigate the effects of their combined use. In this article, we first review the available neurophysiological and behavioral evidence for the effects of combined action observation and motor imagery (AO+MI) on motor processes...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27916763/demographic-and-occupational-determinants-of-the-work-ability-of-firemen
#12
Marjan Firoozeh, Mahnaz Saremi, Amir Kavousi, Azam Maleki
OBJECTIVES: Firefighters tackle various stressors that affect their health and job performance; therefore, assessment of their work ability is necessary. This study aimed to investigate the demographic and occupational determinants of the work ability of firemen. METHODS: In this cross-sectional study, 375 firemen working in Tehran Fire Department were randomly selected. Demographic, occupational, and work ability index (WAI) questionnaires were applied as research tools...
December 2, 2016: Journal of Occupational Health
https://www.readbyqxmd.com/read/27915403/a-simple-approach-for-the-development-of-urban-climatic-maps-based-on-the-urban-characteristics-in-tainan-taiwan
#13
Yu-Cheng Chen, Tzu-Ping Lin, Chien-Ting Lin
Motivated by the increasing thermal load in urban environment, this work established Urban Climatic map (UCmap) focusing on thermal environment issues based on urban development factors, e.g., land cover and building characteristics, representing thermal load of human body and ventilation path in the urban structures. In the established process of UCmap in this work, Tainan city, which is a highly developed city in southern Taiwan, is selected as the research area. A 50-m resolution grid is used to capture urban development factors and the climate data based on 1 year of mobile and fix-point measurements, from which the thermal load and the wind environment map are constructed...
December 3, 2016: International Journal of Biometeorology
https://www.readbyqxmd.com/read/27915303/candida-species-isolated-from-different-body-sites-and-their-antifungal-susceptibility-pattern-cross-analysis-of-candida-albicans-and-candida-glabrata-biofilms
#14
Valentina Cataldi, Emanuela Di Campli, Paolo Fazii, Tonino Traini, Luigina Cellini, Mara Di Giulio
Candida species are regular commensal in humans, but-especially in immunocompromised patients-they represent opportunistic pathogens giving rise to systemic infection. The aim of the present work was to isolate and characterize for their antifungal profile Candida species from different body sites and to analyze the biofilms produced by C. albicans and C. glabrata isolates. Eighty-one strains of Candida species from 77 patients were identified. Epidemiological study showed that the most isolated species were C...
December 2, 2016: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/27915220/stability-maneuverability-trade-offs-during-lateral-steps
#15
Julian Acasio, Mengnan/Mary Wu, Nicholas P Fey, Keith E Gordon
Selecting a specific foot placement strategy to perform walking maneuvers requires the management of several competing factors, including: maintaining stability, positioning oneself to actively generate impulses, and minimizing mechanical energy requirements. These requirements are unlikely to be independent. Our purpose was to determine the impact of lateral foot placement on stability, maneuverability, and energetics during walking maneuvers. Ten able-bodied adults performed laterally-directed walking maneuvers...
November 23, 2016: Gait & Posture
https://www.readbyqxmd.com/read/27914627/comparison-of-in-vivo-measured-loads-in-knee-hip-and-spinal-implants-during-level-walking
#16
Philipp Damm, Ines Kutzner, Georg Bergmann, Antonius Rohlmann, Hendrik Schmidt
Walking is a task that we seek to understand because it is the most relevant human locomotion. Walking causes complex loading patterns and high load magnitudes within the human body. This work summarizes partially published load data collected in earlier in vivo measurement studies on 9 patients with telemeterized knee endoprostheses, 10 with hip endoprostheses and 5 with vertebral body replacements. Moreover, for the 19 endoprosthesis patients, additional simultaneously measured and previously unreported ground reaction forces are presented...
November 28, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/27914539/the-effects-of-alpha-cypermethrin-exposure-on-biochemical-and-redox-parameters-in-pregnant-rats-and-their-newborns
#17
Leila Hocine, Hafida Merzouk, Sid Ahmed Merzouk, Hafeda Ghorzi, Meriem Youbi, Michel Narce
Pyrethroid insecticides are extensively used in agriculture and in household activities. During pregnancy, they might affect maternal metabolic status and there after fetal development. In this work, we studied metabolic and redox effects of low dose alpha-cypermethrin exposure in pregnant rats and their offspring. The diet containing alpha cypermethrin at 0.02mg/kg/day was consumed during the entire gestation. Plasma biochemical parameters as well as liver lipid and oxidative stress markers were determined...
November 2016: Pesticide Biochemistry and Physiology
https://www.readbyqxmd.com/read/27914115/molecular-phylogeny-and-taxonomy-of-a-new-freshwater-hymenostomatid-from-northeastern-china-with-the-establishment-of-a-new-genus-anteglaucoma-gen-n-protista-ciliophora-oligohymenophorea
#18
Xuming Pan, Zihan Shi, Chundi Wang, William A Bourland, Ying Chen, Weibo Song
The morphology, infraciliature and SSU rDNA sequence of a new freshwater hymenostomatid ciliate, Anteglaucoma harbinensis gen. nov., spec. nov., collected from a farmland pond in Harbin, China, were investigated. The new genus Anteglaucoma is characterized as follows: small to medium-sized Glaucomidae with oral apparatus in anterior one-third of cell; paroral membrane composed of almost longitudinally arranged dikinetids; three adoral membranelles nearly equal in length and arranged almost longitudinally in parallel; silverline pattern tetrahymenid...
November 7, 2016: Journal of Eukaryotic Microbiology
https://www.readbyqxmd.com/read/27913821/theobromine-upregulates-osteogenesis-by-human-mesenchymal-stem-cells-in-vitro-and-accelerates-bone-development-in-rats
#19
Bret H Clough, Joni Ylostalo, Elizabeth Browder, Eoin P McNeill, Thomas J Bartosh, H Ralph Rawls, Tetsuo Nakamoto, Carl A Gregory
Theobromine (THB) is one of the major xanthine-like alkaloids found in cacao plant and a variety of other foodstuffs such as tea leaves, guarana and cola nuts. Historically, THB and its derivatives have been utilized to treat cardiac and circulatory disorders, drug-induced nephrotoxicity, proteinuria and as an immune-modulator. Our previous work demonstrated that THB has the capacity to improve the formation of hydroxyl-apatite during tooth development, suggesting that it may also enhance skeletal development...
December 2, 2016: Calcified Tissue International
https://www.readbyqxmd.com/read/27913671/l-rrk-de-triomphe-a-solution-for-lrrk2-gtpase-activity
#20
REVIEW
Jonathon Nixon-Abell, Daniel C Berwick, Kirsten Harvey
Leucine-rich repeat kinase 2 (LRRK2) is a central protein in the pathogenesis of Parkinson's disease (PD), yet its normal function has proved stubbornly hard to elucidate. Even though it remains unclear how pathogenic mutations affect LRRK2 to cause PD, recent findings provide increasing cause for optimism. We summarise here the developing consensus over the effect of pathogenic mutations in the Ras of complex proteins and C-terminal of Roc domains on LRRK2 GTPase activity. This body of work has been greatly reinforced by our own study of the protective R1398H variant contained within the LRRK2 GTPase domain...
December 15, 2016: Biochemical Society Transactions
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