Andre M Paschoal, Joseph G Woods, Joana Pinto, Esther E Bron, Jan Petr, Flora A Kennedy McConnell, Laura Bell, Maria-Eleni Dounavi, Cassandra Gould van Praag, Henk J M M Mutsaerts, Aaron Oliver Taylor, Moss Y Zhao, Irène Brumer, Wei Siang Marcus Chan, Jack Toner, Jian Hu, Logan X Zhang, Catarina Domingos, Sara P Monteiro, Patrícia Figueiredo, Alexander G J Harms, Beatriz E Padrela, Channelle Tham, Ahmed Abdalle, Paula L Croal, Udunna Anazodo
PURPOSE: Arterial spin labeling (ASL) is a widely used contrast-free MRI method for assessing cerebral blood flow (CBF). Despite the generally adopted ASL acquisition guidelines, there is still wide variability in ASL analysis. We explored this variability through the ISMRM-OSIPI ASL-MRI Challenge, aiming to establish best practices for more reproducible ASL analysis. METHODS: Eight teams analyzed the challenge data, which included a high-resolution T1-weighted anatomical image and 10 pseudo-continuous ASL datasets simulated using a digital reference object to generate ground-truth CBF values in normal and pathological states...
March 19, 2024: Magnetic Resonance in Medicine