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Immobilisation

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https://www.readbyqxmd.com/read/28526902/retroclival-epidural-haematoma-a-diagnosis-to-suspect-report-of-three-cases-and-review-of-the-literature
#1
Gorka Zabalo, Rodrigo Ortega, Jorge Díaz, Alfonso Vázquez, Daniel de Frutos, Juan Carlos García, Idoya Zazpe
Retroclival epidural haematoma (REDH) has been reported infrequently. It is a rare entity which is probably underdiagnosed. It is most commonly seen in the paediatric population and is generally associated with high-velocity injuries. We report three cases of paediatric patients diagnosed with REDHs: two of them secondary to high-energy trauma related to a motor-vehicle accident and the other a low-energy trauma after a slip while playing football. All three patients were managed conservatively by cervical immobilisation with favourable outcome...
May 20, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28521643/a-magnetic-nanoparticle-labeled-immunoassay-with-europium-and-samarium-for-simultaneous-quantification-of-serum-pepsinogen-i-and-ii
#2
J Fan, H Xiao, J Zhang, B Zhou, L Deng, Y Zhang, B Huang
OBJECTIVE: To develop a novel immunoassay for the simultaneous determination of serum pepsinogen I (PG I) and pepsinogen II (PG II) by combining established methods of time-resolved fluoroimmunoassay (TRFIA) and magnetic nanoparticles separation. MATERIALS AND METHODS: This new immunoassay method was characterised by immobilising primary antibodies on the surface of magnetic particles and labelled with stable fluorescent chelates of europium and samarium. RESULTS: Using magnetic nanoparticles, the TRFIA immunoassay exhibited broad dynamic assay ranges for PG I with detection limit of 0...
May 19, 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28515522/comparison-of-airtraq%C3%A2-mccoy%C3%A2-and-macintosh-laryngoscopes-for-endotracheal-intubation-in-patients-with-cervical-spine-immobilisation-a-randomised-clinical-trial
#3
Vinod Hosalli, B K Arjun, Uday Ambi, Shivanand Hulakund
BACKGROUND AND AIMS: The study aimed at comparing the performance of the novel optical Airtraq™ laryngoscope with the McCoy™ and conventional Macintosh laryngoscopes for ease of endotracheal intubation in patients with neck immobilisation using manual inline axial cervical spine stabilisation (MIAS) technique. METHODS: Ninety consenting American Society of Anaesthesiologist's physical status I-II patients, aged 18-60 years, scheduled for various surgeries requiring tracheal intubation were randomly assigned into three groups of thirty each to undergo intubation with Macintosh, Airtraq™, or McCoy™ laryngoscope with neck immobilisation by MIAS technique...
April 2017: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/28513356/familyplug
#4
(no author information available yet)
This is the first communication app for patients with severe physical disabilities who are in an immobilised and semiconscious state. It allows the user's voice to reach the patient to help reduce feelings of isolation.
May 17, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28511813/conservative-management-of-mallet-injuries-a-national-survey-of-current-practice-in-the-uk
#5
Z Tolkien, S Potter, N Burr, M D Gardiner, J M Blazeby, A Jain, J Henderson
INTRODUCTION: Mallet injuries are common and usually treated conservatively. Various systematic reviews have found a lack of evidence regarding the best management, and it is unclear whether this uncertainty is reflected in current UK practice. METHODS: An online survey was developed to determine the current practice for the conservative treatment of mallet injury among specialist hand clinicians in the UK, including physiotherapists, occupational therapists and surgeons...
April 23, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28508918/-local-anaesthesia-in-ruminants
#6
Karl Nuss, Andrea Schwarz, Simone Ringer
The use of local anaesthesia in ruminants allows many surgical procedures to be conducted free of pain, efficiently and inexpensively in the field. Local anaesthesia combined with sedation and immobilisation of the animal can replace general anaesthesia for many procedures (e. g. castration, claw amputation). The level of difficulty differs among various local anaesthetic techniques: local infiltration of tissue or anaesthesia of the cornual nerve are easily performed, whereas local anaesthesia of the eye, regional anaesthesia in limbs or anaesthesia for umbilical surgery are more difficult to carry out...
May 16, 2017: Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere
https://www.readbyqxmd.com/read/28508763/radiological-outcomes-of-overhead-traction-therapy-for-developmental-dysplasia-of-the-hip-in-non-ambulatory-children
#7
Marcin K Waśko, Szymon Pietrzak, Anna Szarejko, Waldemar Przybysz, Tomasz Parol, Jarosław Czubak
BACKGROUND: Infants with a dislocated and unstable hip that does not lend itself to stabilisation may be treated using overhead traction to achieve gradual reduction of the hip joint. The aim of this paper was to analyse the radiological outcomes of overhead traction therapy and the effect of duration of traction on the occurrence of complications and final treatment outcomes. Material and methodd. A retrospective analysis of medical records of 26 children (34 affected hips) involved three independent observers assessing radiological parameters before the surgery and at follow-up visits at least two years after the therapy...
April 12, 2017: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28501686/immobilisation-on-mesoporous-silica-and-solvent-rinsing-improve-the-transesterification-abilities-of-feruloyl-esterases-from-myceliophthora-thermophila
#8
Silvia Hüttner, Milene Zezzi Do Valle Gomes, Laura Iancu, Anders Palmqvist, Lisbeth Olsson
The immobilisation of four feruloyl esterases (FAEs) (FaeA1, FaeA2, FaeB1, FaeB2) from the thermophilic fungus Myceliophthora thermophila C1 was studied and optimised via physical adsorption onto various mesoporous silica particles with pore diameters varying from 6.6nm to 10.9nm. Using crude enzyme preparations, enrichment of immobilised FAEs was observed, depending on pore diameter and protein size. The immobilised enzymes were successfully used for the synthesis of butyl ferulate through transesterification of methyl ferulate with 1-butanol...
April 29, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28501199/developing-a-sensor-layer-for-the-optical-detection-of-amines-during-food-spoilage
#9
Cindy Schaude, Claudia Meindl, Eleonore Fröhlich, Jennifer Attard, Gerhard J Mohr
A colourimetric sensor layer has been developed for ammonia and biogenic amines. Amine exposure induces a traffic light colour change from green to red. Recognition is performed by a pH indicator dye, covalently immobilised onto cellulose microparticles. The sensor microparticles are embedded into food-grade silicone. Selectivity of the pH indicator dye towards gaseous amine is obtained by complete embedding of the sensor particles within the ion-impermeable silicone. A response time of 1.5h has been achieved, with a reverse response occurring after 20h...
August 1, 2017: Talanta
https://www.readbyqxmd.com/read/28497711/production-and-covalent-immobilisation-of-the-recombinant-bacterial-carbonic-anhydrase-sspca-onto-magnetic-nanoparticles
#10
Rosa Perfetto, Sonia Del Prete, Daniela Vullo, Giovanni Sansone, Carmela M A Barone, Mosè Rossi, Claudiu T Supuran, Clemente Capasso
Carbonic anhydrases (CAs; EC 4.2.1.1) are metalloenzymes with a pivotal potential role in the biomimetic CO2 capture process (CCP) because these biocatalysts catalyse the simple but physiologically crucial reaction of carbon dioxide hydration to bicarbonate and protons in all life kingdoms. The CAs are among the fastest known enzymes, with kcat values of up to 10(6) s(-1) for some members of the superfamily, providing thus advantages when compared with other CCP methods, as they are specific for CO2. Thermostable CAs might be used in CCP technology because of their ability to perform catalysis in operatively hard conditions, typical of the industrial processes...
December 2017: Journal of Enzyme Inhibition and Medicinal Chemistry
https://www.readbyqxmd.com/read/28493103/cellulose-derivatives-enhanced-stability-of-alginate-based-beads-loaded-with-lactobacillus-plantarum-lab12-against-low-ph-high-temperature-and-prolonged-storage
#11
Ismail M Fareez, Siong Meng Lim, Nurul Aida Ashyqin Zulkefli, Rakesh K Mishra, Kalavathy Ramasamy
The susceptibility of probiotics to low pH and high temperature has limited their use as nutraceuticals. In this study, enhanced protection of probiotics via microencapsulation was achieved. Lactobacillus plantarum LAB12 were immobilised within polymeric matrix comprised of alginate (Alg) with supplementation of cellulose derivatives (methylcellulose (MC), sodium carboxymethyl cellulose (NaCMC) or hydroxypropyl methylcellulose (HPMC)). L. plantarum LAB12 encapsulated in Alg-HPMC(1.0) and Alg-MC(1.0) elicited improved survivability (91%) in simulated gastric conditions and facilitated maximal release (∼100%) in simulated intestinal condition...
May 10, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/28490076/lipase-mediated-synthesis-of-rutin-fatty-ester-study-of-its-process-parameters-and-solvent-polarity
#12
C Vaisali, Prasanna D Belur, Iyyaswami Regupathi
Lipophilization of antioxidants is recognized as an effective strategy to enhance solubility and thus effectiveness in lipid based food. In this study, an effort was made to optimize rutin fatty ester synthesis in two different solvent systems to understand the influence of reaction system hydrophobicity on the optimum conditions using immobilised Candida antartica lipase. Under unoptimized conditions, 52.14% and 13.02% conversion was achieved in acetone and tert-butanol solvent systems, respectively. Among all the process parameters, water activity of the system was found to show highest influence on the conversion in each reaction system...
October 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28482617/electrically-wired-enzyme-tio2-composite-for-glucose-detection
#13
Joao Henrique Lopes, Francois-Xavier Colson, Jake E Barralet, Geraldine Merle
TiO2, glucose oxidase and carbon nanotube microparticles were ultrasonically formed to provide a large surface area for enzyme immobilisation and a favorable microenvironment for direct electron transfer. This simple architecture nanostructure was used to construct a glucose oxidase biosensor, which demonstrated good analytical performance with high reproducibility, and good detection for pathological glucose level.
July 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28474529/restoring-of-glucose-metabolism-of-an-engineered-yarrowia-lipolytica-for-succinic-acid-production-via-a-simple-and-efficient-adaptive-evolution-strategy
#14
Xiaofeng Yang, Huaimin Wang, Chong Li, Carol Sze Ki Lin
Succinate dehydrogenase inactivation in Yarrowia lipolytica has been demonstrated for robust succinic acid production, whereas the inefficient glucose metabolism has hindered its practical application. In this study, a simple and efficient adaptive evolution strategy via cell immobilisation was conducted in shake flasks, aiming to restore the glucose metabolism of Y. lipolytica mutant PGC01003. After 21 days with 14 generations evolution, the glucose consumption rate increased to 0.30 g/L/h in YPD medium with 150 g/L initial glucose, while poor yeast growth was observed in such medium intially...
May 5, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28466444/a-pilot-study-on-geometrical-uncertainties-for-intra-ocular-cancers-in-radiotherapy
#15
Rachitha Antony, Alan Herschtal, Stephen Todd, Claire Phillips, Annette Haworth
A system for stabilising and monitoring eye movements for linac-based stereotactic radiotherapy associated with the mobile eye, the Eye Tracker, was developed. Whilst the Eye Tracker design is based on a previously reported system, the purpose of this study was to confirm that the modified version can be used with clinically acceptable treatment margins. We report the estimates of the margin required to account for inter- and intra-fraction eye motion based on data from 12 consecutive patients treated with the Eye Tracker system in place...
May 2, 2017: Australasian Physical & Engineering Sciences in Medicine
https://www.readbyqxmd.com/read/28463474/the-height-of-the-cricothyroid-membrane-on-computed-tomography-scans-in-trauma-patients
#16
T Nutbeam, R Clarke, T Luff, D Enki, D Gay
Emergency cricothyrotomy is a common feature in all difficult airway algorithms. It is the final step following a 'can't intubate, can't oxygenate' scenario. It is rarely performed and has a significant failure rate. There is variation in the reported size of the cricothyroid membrane, especially across population groups. Procedural failure may result from attempting to pass a device with too large an external diameter through the cricothyroid membrane. We aimed to determine the maximum height of the cricothyroid membrane in a UK trauma population...
May 2, 2017: Anaesthesia
https://www.readbyqxmd.com/read/28462972/solid-phase-synthesis-of-peptide-selenoesters-via-a-side-chain-anchoring-strategy
#17
Cameron C Hanna, Sameer S Kulkarni, Emma E Watson, Bhavesh Premdjee, Richard J Payne
Peptide selenoesters have recently emerged as key building blocks for the ligation-based assembly of large polypeptides and proteins. Herein, we report an efficient solid-phase method for the high yielding and epimerisation-free synthesis of peptide selenoesters using a side-chain immobilisation strategy.
May 11, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28461966/management-of-the-first-episode-of-traumatic-shoulder-dislocation
#18
REVIEW
Michele Boffano, Stefano Mortera, Raimondo Piana
Shoulder joint dislocation is the most common joint dislocation seen in the emergency department.Traumatic dislocation may cause damage to the soft-tissues surrounding the shoulder joint and sometimes to the bone. The treatment, which aims at restoration of a fully functioning, pain-free and stable shoulder, includes either conservative or surgical management preceded by closed reduction of the acute dislocation.Conservative management usually requires a period of rest, generally involving immobilisation of the arm in a sling, even though it is still debated whether to immobilise the shoulder in internal or external rotation...
February 2017: EFORT Open Rev
https://www.readbyqxmd.com/read/28454185/patella-dislocation-in-children-and-adolescents
#19
Sven Höhne, Kristina Gerlach, Lars Irlenbusch, Mathias Schulz, Christian Kunze, Rainer Finke
Introduction Patellar dislocation is one of the commonest knee injuries in adolescents. Although treatment usually leads to good results, the influence of anatomical and functional factors on therapeutic strategy has been underestimated, especially in cases of recurrence. Patients and Methods The course of treatment has been analysed in 88 patients with 136 patellar dislocations. The importance of anatomical conditions was studied using X-ray and MRI findings. The treatment results were critically evaluated in comparison with current recommendations...
April 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/28453537/an-efficient-and-robust-mri-guided-radiotherapy-planning-approach-for-targeting-abdominal-organs-and-tumours-in-the-mouse
#20
Veerle Kersemans, John S Beech, Stuart Gilchrist, Paul Kinchesh, Philip D Allen, James Thompson, Ana L Gomes, Zenobia D'Costa, Luke Bird, Iain D C Tullis, Robert G Newman, Aurelien Corroyer-Dulmont, Nadia Falzone, Abul Azad, Katherine A Vallis, Owen J Sansom, Ruth J Muschel, Borivoj Vojnovic, Mark A Hill, Emmanouil Fokas, Sean C Smart
INTRODUCTION: Preclinical CT-guided radiotherapy platforms are increasingly used but the CT images are characterized by poor soft tissue contrast. The aim of this study was to develop a robust and accurate method of MRI-guided radiotherapy (MR-IGRT) delivery to abdominal targets in the mouse. METHODS: A multimodality cradle was developed for providing subject immobilisation and its performance was evaluated. Whilst CT was still used for dose calculations, target identification was based on MRI...
2017: PloS One
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