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https://www.readbyqxmd.com/read/28219597/combined-heart-and-kidney-transplantation-a-23-year-experience
#1
M Awad, L S C Czer, F Esmailian, S Jordan, M A De Robertis, J Mirocha, J Patel, D H Chang, M Kittleson, D Ramzy, F Arabia, J S Chung, J L Cohen, A Trento, J A Kobashigawa
BACKGROUND: We report clinical experience with combined heart and kidney transplantation (HKTx) over a 23-year time period. METHODS: From June 1992 to August 2015, we performed 83 combined HKTx procedures at our institution. We compared the more recent cohort of 53 HKTx recipients (group 2, March 2009 to August 2015) with the initial 30 previously reported HKTx recipients (group 1, June 1992 to February 2009). Pre-operative patient characteristics, peri-operative factors, and post-operative outcomes including survival were examined...
March 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28219580/use-of-anti-thymocyte-globulin-for-induction-therapy-in-cardiac-transplantation-a-review
#2
V Ruan, L S C Czer, M Awad, M Kittleson, J Patel, F Arabia, F Esmailian, D Ramzy, J Chung, M De Robertis, A Trento, J A Kobashigawa
The most common causes of death after heart transplantation (HTx) include acute rejection and multi-organ failure in the early period and malignancy and cardiac allograft vasculopathy (CAV) in the late period. Polyclonal antibody preparations such as rabbit anti-thymocyte globulin (ATG) may reduce early acute rejection and the later occurrence of CAV after HTx. ATG therapy depletes T cells, modulates adhesion and cell-signaling molecules, interferes with dendritic cell function, and induces B-cell apoptosis and regulatory and natural killer T-cell expansion...
March 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28213797/long-term-outcomes-of-tot-and-tvt-procedures-for-the-treatment-of-female-stress-urinary-incontinence-a-systematic-review-and-meta-analysis
#3
REVIEW
Umberto Leone Roberti Maggiore, Enrico Finazzi Agrò, Marco Soligo, Vincenzo Li Marzi, Alex Digesu, Maurizio Serati
INTRODUCTION AND HYPOTHESES: One of the most relevant topics in the field of pelvic floor dysfunction treatment is the long-term efficacy of surgical procedures, in particular, the use of prosthesis. Hence, a systematic review and meta-analysis was conducted to evaluate the long-term effectiveness and safety of midurethral sling (MUS) procedures for stress urinary incontinence (SUI), as reported in randomised controlled trials (RCTs) and non-randomised studies. METHODS: This systematic review is based on material searched and obtained via PubMed/Medline, Scopus, and the Cochrane Library between January 2000 and October 2016...
February 17, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28203546/complex-robotic-correction-for-complex-degenerative-mitral-valve-disease
#4
REVIEW
Danny Ramzy, Joshua Chung, Wen Cheng, Michele A De Robertis, James Mirocha, Alfredo Trento
No abstract text is available yet for this article.
January 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28183132/-i-aphis-i-species-hemiptera-aphididae-living-on-i-mulinum-i-apiaceae-in-south-america-with-a-description-of-a-new-species
#5
Sandra González Rodríguez, Paul A Brown, Jaime Ortego, Sara I López Ciruelos, Juan M Nieto Nafría
Aphis species living on the South American native genus Mulinum are studied. Aphis vurilocensis Nieto Nafría, Brown and López Ciruelos, sp. n. is described from apterous viviparous females. Alate viviparous females, oviparous females and winged males of Aphis roberti are described. Knowledge of intraspecific variability of apterous viviparous females of A. martinezi, A. paravanoi and A. roberti is developed. An identification key of apterous viviparous females of Aphis species living on Mulinum is presented...
January 3, 2017: Zootaxa
https://www.readbyqxmd.com/read/28178576/the-association-of-pre-treatment-hpv-subtypes-with-recurrence-of-vin
#6
Giorgio Bogani, Fabio Martinelli, Antonino Ditto, Mauro Signorelli, Francesca Taverna, Claudia Lombardo, Valentina Chiappa, Umberto Leone Roberti Maggiore, Dario Recalcati, Cono Scaffa, Stefania Perotto, Ilaria Sabatucci, Alice Indini, Domenica Lorusso, Francesco Raspagliesi
OBJECTIVE: To assess whether pre-treatment HPV types are associated with recurrence of high-grade vulvar intraepithelial neoplasia (VIN2+). STUDY DESIGN: Data of consecutive patients with pretreatment HPV DNA test undergoing treatment for VIN2+ were retrospectively collected. Risk factors promoting the risk of VIN2+ persistence and recurrence were analyzed using Kaplan-Meier and Cox hazard proportional models. RESULTS: 64 patients had pretreatment vulvar-vaginal HPV DNA test...
February 1, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28176617/progressive-multifocal-leukoencephalopathy-in-a-kidney-transplant-recipient
#7
Federico Cicora, Javier Roberti
Progressive multifocal leukoencephalopathy (PML) is a debilitating and often fatal viral disease of the central nervous system. A 39-year-old male kidney transplant recipient presented to our hospital with weakness of the left arm and leg, his immunosuppressive regimen consisted of tacrolimus, mycophenolate sodium, and meprednisone. Magnetic resonance imaging of the brain revealed hypercellularity in neural tissue and a lesion affecting the right ventral and lateral areas of the thalamus and the posterior limb of the internal capsule...
February 7, 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/28158530/usefulness-of-3d-echocardiographic-parameters-of-tricuspid-valve-morphology-to-predict-residual-tricuspid-regurgitation-after-tricuspid-annuloplasty
#8
Hiroto Utsunomiya, Yuji Itabashi, Hirotsugu Mihara, Sayuki Kobayashi, Michele A De Robertis, Alfredo Trento, Takahiro Shiota
No abstract text is available yet for this article.
January 30, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28130803/mitral-annular-motion-in-patients-after-transcatheter-mitraclip-and-mitral-valve-surgery
#9
Kentaro Toyama, Florian Rader, Kengo Ayabe, Saibal Kar, Alfredo Trento, Toshihiko Nishioka, Michele A De Robertis, Robert J Siegel
BACKGROUND: Longitudinal motion of the mitral annulus is an index that reflects left ventricular (LV) function. The aim of this study was to evaluate and compare the effects of transcatheter mitral valve (MV) repair and open heart surgery for mitral regurgitation (MR) on mitral annular motion (MAM). METHODS: We retrospectively analyzed in total 115 patients who underwent isolated transcatheter MV repair using MitraClip (n=50) or surgical MV interventions (n=65, 50 repairs and 15 replacements) for MR...
January 28, 2017: Echocardiography
https://www.readbyqxmd.com/read/28129238/impact-of-blood-transfusions-on-survival-of-locally-advanced-cervical-cancer-patients-undergoing-neoadjuvant-chemotherapy-plus-radical-surgery
#10
Giorgio Bogani, Antonino Ditto, Fabio Martinelli, Mauro Signorelli, Valentina Chiappa, Carlos Lopez, Alice Indini, Umberto Leone Roberti Maggiore, Ilaria Sabatucci, Domenica Lorusso, Francesco Raspagliesi
OBJECTIVE: Transfusions represent one of the main progresses of modern medicine. However, accumulating evidence supports that transfusions correlate with worse survival outcomes in patients affected by solid cancers. In the present study, we aimed to investigate the effects of perioperative blood transfusion in locally advanced cervical cancer. METHODS: Data of consecutive patients affected by locally advanced cervical cancer scheduled to undergo neoadjuvant chemotherapy plus radical surgery were retrospectively searched to test the impact of perioperative transfusions on survival outcomes...
March 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28127201/pancreatic-neuroendocrine-neoplasms-magnetic-resonance-imaging-features-according-to-grade-and-stage
#11
Riccardo De Robertis, Sara Cingarlini, Paolo Tinazzi Martini, Silvia Ortolani, Giovanni Butturini, Luca Landoni, Paolo Regi, Roberto Girelli, Paola Capelli, Stefano Gobbo, Giampaolo Tortora, Aldo Scarpa, Paolo Pederzoli, Mirko D'Onofrio
AIM: To describe magnetic resonance (MR) imaging features of pancreatic neuroendocrine neoplasms (PanNENs) according to their grade and tumor-nodes-metastases stage by comparing them to histopathology and to determine the accuracy of MR imaging features in predicting their biological behavior. METHODS: This study was approved by our institutional review board; requirement for informed patient consent was waived due to the retrospective nature of the study. Preoperative MR examinations of 55 PanNEN patients (29 men, 26 women; mean age of 57...
January 14, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28124130/mechanisms-and-situations-of-anterior-cruciate-ligament-injuries-in-professional-male-soccer-players-a-youtube-based-video-analysis
#12
Alberto Grassi, Stephen Paul Smiley, Tommaso Roberti di Sarsina, Cecilia Signorelli, Giulio Maria Marcheggiani Muccioli, Alice Bondi, Matteo Romagnoli, Alessandra Agostini, Stefano Zaffagnini
BACKGROUND: Soccer is considered the most popular sport in the world concerning both audience and athlete participation, and the incidence of ACL injury in this sport is high. The understanding of injury situations and mechanisms could be useful as substratum for preventive actions. PURPOSE: To conduct a video analysis evaluating the situations and mechanisms of ACL injury in a homogeneous population of professional male soccer players, through a search entirely performed on the YouTube...
January 25, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28124103/surgical-treatment-of-infected-shoulder-arthroplasty-a-systematic-review
#13
REVIEW
Giulio Maria Marcheggiani Muccioli, Gazi Huri, Alberto Grassi, Tommaso Roberti di Sarsina, Giuseppe Carbone, Enrico Guerra, Edward G McFarland, Mahmut N Doral, Maurilio Marcacci, Stefano Zaffagnini
PURPOSE: To investigate the best surgical management of infected shoulder arthroplasty. METHODS: A literature review from 1996 to 2016 identified 15 level IV studies that met inclusion criteria. Persistent infection (PI) was considered as treatment failure. Success was regarded as the absence of symptomatic PI without necessity for further treatment. Surgical outcomes were reported according to the mean weighted Constant and Murley score (CMS) for each treatment group...
January 26, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28106352/a-year-in-review-in-minerva-anestesiologica-2016-critical-care-experimental-and-clinical-studies
#14
Franco Cavaliere, Guillermo M Albaiceta, Gianni Biancofiore, Elena Bignami, Edoardo DE Robertis, Alberto Giannini, Salvatore Grasso, Sabino Scolletta, Peter Spieth, Fabio S Taccone, Pierpaolo Terragni
No abstract text is available yet for this article.
January 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/28101307/review-and-recommendations-on-management-of-adult-female-thalassemia-patients-with-hypogonadism-based-on-literature-review-and-experience-of-icet-a-network-specialists
#15
REVIEW
Vincenzo De Sanctis, Ashraf T Soliman, Heba Elsedfy, Alice Albu, Soad Al Jaouni, Salvatore Anastasi, Maria Grazia Bisconte, Duran Canatan, Soteroula Christou, Shahina Daar, Salvatore Di Maio, Mohamed El Kholy, Doaa Khater, Mohamed Elshinawy, Yurdanur Kilinc, Roberto Mattei, Hala H Mosli, Alessandra Quota, Maria Grazia Roberti, Praveen Sobti, Saif Al Yaarubi, Saveria Canpisi, Christos Kattamis
BACKGROUND: Multi-transfused thalassemia major (TM) patients frequently develop severe endocrine complications, mainly due to iron overload, anemia, and chronic liver disease, which require prompt diagnosis, treatment and follow-up by specialists. The most common endocrine complication documented is hypogonadotropic hypogonadism which increases with age and associated comorbidities. It is thus important for physicians to have a clear understanding of the pathophysiology and management of this disorder...
2017: Mediterranean Journal of Hematology and Infectious Diseases
https://www.readbyqxmd.com/read/28077504/influence-of-history-of-cannabis-smoking-in-selected-donors-on-the-outcomes-of-lung-transplantation
#16
Prashant N Mohite, Mohamed Zeriouh, Diana G Sáez, Aron-Frederik Popov, Anton Sabashnikov, Bartlomiej Zych, Ashok Padukone, Levente Fazekas, Olga Ananiadou, Fabio De Robertis, Simona Soresi, Anna Reed, Martin Carby, André R Simon
OBJECTIVES: Cannabis is the most commonly abused illicit drug and the smokers are at the risk of lung infections, bullous emphysema and lung cancer. However, no evidence about the outcomes of lung transplantation (LTx) utilizing the lungs from such donors is available in the literature. METHODS: We retrospectively analysed lung 'organ offers' and LTx at our centre between January 2007 and November 2013. The outcomes of LTx utilizing lungs from donors with a history of cannabis smoking were compared with the outcomes of those with no such history using unadjusted model as well as propensity score matching...
January 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28068360/exploring-serum-levels-of-brain-derived-neurotrophic-factor-and-nerve-growth-factor-across-glaucoma-stages
#17
Francesco Oddone, Gloria Roberti, Alessandra Micera, Anna Busanello, Stefano Bonini, Luciano Quaranta, Luca Agnifili, Gianluca Manni
PURPOSE: To investigate the serum levels of Brain Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF) in patients affected by primary open angle glaucoma with a wide spectrum of disease severity compared to healthy controls and to explore their relationship with morphological and functional glaucoma parameters. MATERIALS AND METHODS: 45 patients affected by glaucoma at different stages and 15 age-matched healthy control subjects underwent visual field testing, peripapillary retinal nerve fibre layer thickness measurement using Spectral Domain Optical Coherence Tomography and blood collection for both neurotrophins detection by Enzyme-Linked Immunosorbent Assay...
2017: PloS One
https://www.readbyqxmd.com/read/28064079/tacrine-resveratrol-fused-hybrids-as-multi-target-directed-ligands-against-alzheimer-s-disease
#18
Jakub Jeřábek, Elisa Uliassi, Laura Guidotti, Jan Korábečný, Ondřej Soukup, Vendula Sepsova, Martina Hrabinova, Kamil Kuča, Manuela Bartolini, Luis Emiliano Peña-Altamira, Sabrina Petralla, Barbara Monti, Marinella Roberti, Maria Laura Bolognesi
Multi-target drug discovery is one of the most followed approaches in the active central nervous system (CNS) therapeutic area, especially in the search for new drugs against Alzheimer's disease (AD). This is because innovative multi-target-directed ligands (MTDLs) could more adequately address the complexity of this pathological condition. In a continuation of our efforts aimed at a new series of anti-AD MTDLs, we combined the structural features of the cholinesterase inhibitor drug tacrine with that of resveratrol, which is known for its purported antioxidant and anti-neuroinflammatory activities...
December 26, 2016: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28040358/bladder-endometriosis-a-systematic-review-of-pathogenesis-diagnosis-treatment-impact-on-fertility-and-risk-of-malignant-transformation
#19
REVIEW
Umberto Leone Roberti Maggiore, Simone Ferrero, Massimo Candiani, Edgardo Somigliana, Paola Viganò, Paolo Vercellini
CONTEXT: The bladder is the most common site affected in urinary tract endometriosis. There is controversy regarding the pathogenesis, clinical management (diagnosis and treatment), impact on fertility, and risk of malignant transformation of bladder endometriosis (BE). OBJECTIVE: To systematically evaluate evidence regarding the pathogenesis, diagnosis, medical and surgical treatment, impact on female fertility, and risk of malignant transformation of BE. EVIDENCE ACQUISITION: A systematic review of PubMed/Medline from inception until October 2016 was performed in accordance with the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) statement and was registered in the PROSPERO registry (www...
December 28, 2016: European Urology
https://www.readbyqxmd.com/read/28039759/human-papillomavirus-hpv-persistence-and-hpv-31-predict-the-risk-of-recurrence-in-high-grade-vaginal-intraepithelial-neoplasia
#20
Giorgio Bogani, Fabio Martinelli, Antonino Ditto, Francesca Taverna, Claudia Lombardo, Mauro Signorelli, Valentina Chiappa, Umberto Leone Roberti Maggiore, Caterina Fontanella, Ilaria Sabatucci, Chiara Borghi, Dario Recalcati, Alice Indini, Domenica Lorusso, Francesco Raspagliesi
OBJECTIVE: High-grade vaginal intraepithelial neoplasia (vaginal HSIL) represents an uncommon entity. Here, we sought to identify predictors for recurrence and risk factor for developing genital cancers after primary treatment for vaginal HSIL. METHODS: Data of consecutive 5104 women who had human papillomavirus (HPV) DNA test were searched for identify women with histological confirmed vaginal HSIL. Disease-free interval and the risk of developing HPV-related gynecological cancers were assessed using Kaplan-Meier and Cox proportional hazard models...
December 23, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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