keyword
MENU ▼
Read by QxMD icon Read
search

roberta

keyword
https://www.readbyqxmd.com/read/28449403/effects-of-malnutrition-on-treatment-related-morbidity-and-survival-of-children-with-cancer-in-nicaragua
#1
Allison K Pribnow, Roberta Ortiz, Luis Fulgencio Báez, Luvy Mendieta, Sandra Luna-Fineman
BACKGROUND: Most children with cancer live in resource-limited countries where malnutrition is often prevalent. We identified the relationship between malnutrition and treatment-related morbidity (TRM), abandonment of therapy, and survival of children with cancer in Nicaragua to better inform targeted nutritional interventions. PROCEDURE: We conducted a retrospective review of patients aged 6 months to 18 years with newly diagnosed acute lymphoblastic leukemia, acute myeloid leukemia (AML), Wilms tumor, Hodgkin lymphoma, or Burkitt lymphoma (BL) who were treated between January 1, 2004, and December 31, 2007 at Children's Hospital Manuel de Jesus Rivera in Managua, Nicaragua...
April 27, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28449126/results-of-the-answer-trial-using-the-pulserider-for-the-treatment-of-broad-necked-bifurcation-aneurysms
#2
Alejandro M Spiotta, Colin P Derdeyn, Satoshi Tateshima, Jay Mocco, R Webster Crowley, Kenneth C Liu, Lee Jensen, Koji Ebersole, Alan Reeves, Demetrius K Lopes, Ricardo A Hanel, Eric Sauvageau, Gary Duckwiler, Adnan Siddiqui, Elad Levy, Ajit Puri, Lee Pride, Roberta Novakovic, M Imran Chaudry, Raymond D Turner, Aquilla S Turk
BACKGROUND: The safety and probable benefit of the PulseRider (Pulsar Vascular, Los Gatos, California) for the treatment of broad-necked, bifurcation aneurysms was studied in the context of the prospective, nonrandomized, single arm clinical trial-the Adjunctive Neurovascular Support of Wide-neck aneurysm Embolization and Reconstruction (ANSWER) Trial. OBJECTIVE: To present the results of the United States cases employing the PulseRider device as part of the ANSWER clinical trial...
April 25, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28448448/in-vitro-ex-vivo-and-in-vivo-techniques-to-study-neuronal-migration-in-the-developing-cerebral-cortex
#3
REVIEW
Roberta Azzarelli, Roberto Oleari, Antonella Lettieri, Valentina Andre', Anna Cariboni
Neuronal migration is a fundamental biological process that underlies proper brain development and neuronal circuit formation. In the developing cerebral cortex, distinct neuronal populations, producing excitatory, inhibitory and modulatory neurotransmitters, are generated in different germinative areas and migrate along various routes to reach their final positions within the cortex. Different technical approaches and experimental models have been adopted to study the mechanisms regulating neuronal migration in the cortex...
April 27, 2017: Brain Sciences
https://www.readbyqxmd.com/read/28447241/abbreviated-breast-dynamic-contrast-enhanced-mr-imaging-for-lesion-detection-and-characterization-the-experience-of-an-italian-oncologic-center
#4
Antonella Petrillo, Roberta Fusco, Mario Sansone, Marilena Cerbone, Salvatore Filice, Annamaria Porto, Maria Rosaria Rubulotta, Massimiliano D'Aiuto, Franca Avino, Maurizio Di Bonito, Gerardo Botti
BACKGROUND: To evaluate the performance of an abbreviated dynamic contrast-enhanced MR imaging (MRI) protocol for breast cancer detection; a comparison with the complete diagnostic protocol has been conducted. METHODS: A retrospective analysis on 508 patients was performed. Abbreviated protocol (AP) included one pre-contrast and the first post-contrast T1-weighted series. Complete protocol (CP) consisted of four post-contrast and one pre-contrast T1-weighted series...
April 26, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28447221/deleterious-abca7-mutations-and-transcript-rescue-mechanisms-in-early-onset-alzheimer-s-disease
#5
Arne De Roeck, Tobi Van den Bossche, Julie van der Zee, Jan Verheijen, Wouter De Coster, Jasper Van Dongen, Lubina Dillen, Yalda Baradaran-Heravi, Bavo Heeman, Raquel Sanchez-Valle, Albert Lladó, Benedetta Nacmias, Sandro Sorbi, Ellen Gelpi, Oriol Grau-Rivera, Estrella Gómez-Tortosa, Pau Pastor, Sara Ortega-Cubero, Maria A Pastor, Caroline Graff, Håkan Thonberg, Luisa Benussi, Roberta Ghidoni, Giuliano Binetti, Alexandre de Mendonça, Madalena Martins, Barbara Borroni, Alessandro Padovani, Maria Rosário Almeida, Isabel Santana, Janine Diehl-Schmid, Panagiotis Alexopoulos, Jordi Clarimon, Alberto Lleó, Juan Fortea, Magda Tsolaki, Maria Koutroumani, Radoslav Matěj, Zdenek Rohan, Peter De Deyn, Sebastiaan Engelborghs, Patrick Cras, Christine Van Broeckhoven, Kristel Sleegers
Premature termination codon (PTC) mutations in the ATP-Binding Cassette, Sub-Family A, Member 7 gene (ABCA7) have recently been identified as intermediate-to-high penetrant risk factor for late-onset Alzheimer's disease (LOAD). High variability, however, is observed in downstream ABCA7 mRNA and protein expression, disease penetrance, and onset age, indicative of unknown modifying factors. Here, we investigated the prevalence and disease penetrance of ABCA7 PTC mutations in a large early onset AD (EOAD)-control cohort, and examined the effect on transcript level with comprehensive third-generation long-read sequencing...
April 27, 2017: Acta Neuropathologica
https://www.readbyqxmd.com/read/28446908/association-of-ctla-4-gene-variants-with-response-to-therapy-and-long-term-survival-in-metastatic-melanoma-patients-treated-with-ipilimumab-an-italian-melanoma-intergroup-study
#6
Paola Queirolo, Beatrice Dozin, Anna Morabito, Barbara Banelli, Patrizia Piccioli, Cristiana Fava, Claudio Leo, Roberta Carosio, Stefania Laurent, Vincenzo Fontana, Pier Francesco Ferrucci, Chiara Martinoli, Emilia Cocorocchio, Angelo Battaglia, Paolo A Ascierto, Mariaelena Capone, Ester Simeone, Federica De Galitiis, Elena Pagani, Gian Carlo Antonini Cappellini, Paolo Marchetti, Michele Guida, Stefania Tommasi, Mario Mandalà, Barbara Merelli, Pietro Quaglino, Paolo Fava, Massimo Guidoboni, Massimo Romani, Francesco Spagnolo, Maria Pia Pistillo
Ipilimumab (IPI) blocks CTLA-4 immune checkpoint resulting in T cell activation and enhanced antitumor immunity. IPI improves overall survival (OS) in 22% of patients with metastatic melanoma (MM). We investigated the association of CTLA-4 single nucleotide variants (SNVs) with best overall response (BOR) to IPI and OS in a cohort of 173 MM patients. Patients were genotyped for six CTLA-4 SNVs (-1661A>G, -1577G>A, -658C>T, -319C>T, +49A>G, and CT60G>A). We assessed the association between SNVs and BOR through multinomial logistic regression (MLR) and the prognostic effect of SNVs on OS through Kaplan-Meier method...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28446736/violating-organizational-and-social-norms-in-the-workplace-a-correlational-study-in-the-nursing-context
#7
Francesco Zaghini, Valentina Biagioli, Rosario Caruso, Sondra Badolamenti, Roberta Fida, Alessandro Sili
OBJECTIVES: The aim of this study was to examine, in a sample of nurses, the relationships between the organizational context variables (i.e., workload, interpersonal conflicts, organizational constraints), the burnout, the moral disengagement, and the counterproductive work behaviors (CWB), within their clinical work settings. METHODS: A descriptive, correlational study was conducted in a sample of 347 nurses working in different clinical settings in a big university hospital in Central Italy...
April 21, 2017: La Medicina del Lavoro
https://www.readbyqxmd.com/read/28444624/targeting-ntrk-fusion-in-non-small-cell-lung-cancer-rationale-and-clinical-evidence
#8
REVIEW
Biagio Ricciuti, Marta Brambilla, Giulio Metro, Sara Baglivo, Roberta Matocci, Matteo Pirro, Rita Chiari
In the era of personalized medicine, the identification of targetable genetic alterations represented a major step forward in anticancer therapy. NTRK rearrangements represent the molecular driver of a subset of solid tumors, including 3% of non-small-cell lung cancers (NSCLCs). Preliminary data indicate that molecularly selected NSCLC patients harboring NTRK fusions derive an unprecedented clinical benefit from Trk-directed targeted therapies. The aim of this review is to describe the molecular biology of NTRK signaling pathway and to summarize the preclinical data on novel Trk inhibitors, touching upon the clinical development of these inhibitors for the treatment of advanced NSCLC, which have already shown encouraging anticancer activity and acceptable safety profile in early phase I clinical trials...
June 2017: Medical Oncology
https://www.readbyqxmd.com/read/28443038/mother-infant-and-extra-dyadic-interactions-with-a-new-social-partner-developmental-trajectories-of-early-social-abilities-during-play
#9
Roberta Fadda, Loredana Lucarelli
Mother-infant interactions during feeding and play are pivotal experiences in the development of infants' early social abilities (Stern, 1985, 1995; Biringen, 2000). Stern indicated distinctive characteristics of mother-infant interactions, respectively, during feeding and play, suggesting to evaluate both to better describe the complexity of such early affective and social experiences (Stern, 1996). Moreover, during the first years of life, infants acquire cognitive and social skills that allow them to interact with new social partners in extra-dyadic interactions...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28442708/the-complete-12%C3%A2-mb-genome-and-transcriptome-of-nonomuraea-gerenzanensis-with-new-insights-into-its-duplicated-magic-rna-polymerase
#10
Valeria D'Argenio, Mauro Petrillo, Daniela Pasanisi, Caterina Pagliarulo, Roberta Colicchio, Adelfia Talà, Maria Stella de Biase, Mario Zanfardino, Emanuela Scolamiero, Chiara Pagliuca, Antonio Gaballo, Annunziata Gaetana Cicatiello, Piergiuseppe Cantiello, Irene Postiglione, Barbara Naso, Angelo Boccia, Miriana Durante, Luca Cozzuto, Paola Salvatore, Giovanni Paolella, Francesco Salvatore, Pietro Alifano
In contrast to the widely accepted consensus of the existence of a single RNA polymerase in bacteria, several actinomycetes have been recently shown to possess two forms of RNA polymerases due the to co-existence of two rpoB paralogs in their genome. However, the biological significance of the rpoB duplication is obscure. In this study we have determined the genome sequence of the lipoglycopeptide antibiotic A40926 producer Nonomuraea gerenzanensis ATCC 39727, an actinomycete with a large genome and two rpoB genes, i...
December 21, 2016: Scientific Reports
https://www.readbyqxmd.com/read/28442332/the-individual-preferred-velocity-of-stroking-touch-as-a-stable-measurement
#11
Amanda Luong, Johanna Bendas, Roberta Etzi, Håkan Olausson, Ilona Croy
Affective touch is of fundamental importance in human social interactions and there is an increasing interest in using touch as a probe for general affective perception. To this end, we developed a test of preferred velocity (ToP-V) of touch and tested whether the individually preferred stroking velocity is a stable and valid measurement. In study one, thirty healthy participants (18-30years, 17 women) were examined with the ToP-V. Therefore, pairs of different slow stroking stimuli were presented by the Rotary Tactile Stimulator - a robotic device - on the forearm and the participants chose the velocity they preferred in a forced choice paradigm...
April 22, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28442211/leigh-like-neuroimaging-features-associated-with-new-biallelic-mutations-in-opa1
#12
Anna Rubegni, Tiziana Pisano, Giacomo Bacci, Alessandra Tessa, Roberta Battini, Elena Procopio, Sabrina Giglio, Rosa Pasquariello, Filippo Maria Santorelli, Renzo Guerrini, Claudia Nesti
Behr syndrome is characterized by the association of early onset optic atrophy, cerebellar ataxia, pyramidal signs, peripheral neuropathy and mental retardation. Recently, some cases were reported to be caused by biallelic mutations in OPA1. We describe an 11-year-old girl (Pt1) and a 7-year-old boy (Pt2) with cognitive delay, ataxic gait and clinical signs suggestive of a peripheral neuropathy, with onset in early infancy. In Pt1 ocular fundus examination revealed optic disk pallor whereas Pt2 exhibited severe optic atrophy...
April 15, 2017: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/28442058/nuclear-transfer-alters-placental-gene-expression-and-associated-histone-modifications-of-the-placental-specific-imprinted-gene-pleckstrin-homology-like-domain-family-a-member-2-phlda2-in-cattle
#13
Daniel R Arnold, Roberta C Gaspar, Carlos V da Rocha, Juliano R Sangalli, Tiago H C de Bem, Carolina A P Corrêa, João C T Penteado, Flavio V Meirelles, Flavia L Lopes
Abnormal placental development is frequent in nuclear transfer (NT) pregnancies and is likely to be associated with altered epigenetic reprogramming. In the present study, fetal and placental measurements were taken on Day 60 of gestation in cows with pregnancies produced by AI, IVF and NT. Placentas were collected and subjected to histological evaluation, the expression of genes important in trophoblast differentiation and expression of the placental imprinted gene pleckstrin homology-like domain, family A, member 2 (PHLDA2), as well as chromatin immunoprecipitation (ChIP) for histone marks within the promoter of PHLDA2...
March 2017: Reproduction, Fertility, and Development
https://www.readbyqxmd.com/read/28441638/health-risk-assessment-for-the-consumption-of-fresh-and-preserved-fish-alosa-agone-from-lago-di-como-northern-italy
#14
Silvia Quadroni, Roberta Bettinetti
BACKGROUND: Although banned in many countries for decades, DDTs and PCBs still represent a global threat to food safety. As these contaminants are still present in aquatic ecosystems, fish can be an important contributor to their total dietary intake. OBJECTIVES: Alosa agone specimens were sampled over a period of 10 years (from 2006 to 2015) to provide a representative overview of the DDT and PCB levels of Lago di Como, a deep Italian lake where a DDT input due to secondary sources was observed in recent years...
April 22, 2017: Environmental Research
https://www.readbyqxmd.com/read/28441382/hedgehog-signalling-pathway-orchestrates-angiogenesis-in-triple-negative-breast-cancers
#15
Concetta Di Mauro, Roberta Rosa, Valentina D'Amato, Paola Ciciola, Alberto Servetto, Roberta Marciano, Roberta Clara Orsini, Luigi Formisano, Sandro De Falco, Valeria Cicatiello, Maurizio Di Bonito, Monica Cantile, Francesca Collina, Angela Chambery, Bianca Maria Veneziani, Sabino De Placido, Roberto Bianco
BACKGROUND: Several evidences suggest a marked angiogenic dependency in triple-negative breast cancer (TNBC) tumorigenesis and a potential sensitivity to anti-angiogenic agents. Herein, the putative role of Hedgehog (Hh) pathway in regulating TNBC-dependent angiogenesis was investigated. METHODS: Expression and regulation of the Hh pathway transcription factor glioma-associated oncogene homolog1 protein (GLI1) were studied on the endothelial compartment and on TNBC-initiated angiogenesis...
April 25, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28441085/noun-and-verb-knowledge-in-monolingual-preschool-children-across-17-languages-data-from-cross-linguistic-lexical-tasks-litmus-clt
#16
Ewa Haman, Magdalena Łuniewska, Pernille Hansen, Hanne Gram Simonsen, Shula Chiat, Jovana Bjekić, Agnė Blažienė, Katarzyna Chyl, Ineta Dabašinskienė, Pascale Engel de Abreu, Natalia Gagarina, Anna Gavarró, Gisela Håkansson, Efrat Harel, Elisabeth Holm, Svetlana Kapalková, Sari Kunnari, Chiara Levorato, Josefin Lindgren, Karolina Mieszkowska, Laia Montes Salarich, Anneke Potgieter, Ingeborg Ribu, Natalia Ringblom, Tanja Rinker, Maja Roch, Daniela Slančová, Frenette Southwood, Roberta Tedeschi, Aylin Müge Tuncer, Özlem Ünal-Logacev, Jasmina Vuksanović, Sharon Armon-Lotem
This article investigates the cross-linguistic comparability of the newly developed lexical assessment tool Cross-linguistic Lexical Tasks (LITMUS-CLT). LITMUS-CLT is a part the Language Impairment Testing in Multilingual Settings (LITMUS) battery (Armon-Lotem, de Jong & Meir, 2015). Here we analyse results on receptive and expressive word knowledge tasks for nouns and verbs across 17 languages from eight different language families: Baltic (Lithuanian), Bantu (isiXhosa), Finnic (Finnish), Germanic (Afrikaans, British English, South African English, German, Luxembourgish, Norwegian, Swedish), Romance (Catalan, Italian), Semitic (Hebrew), Slavic (Polish, Serbian, Slovak) and Turkic (Turkish)...
April 25, 2017: Clinical Linguistics & Phonetics
https://www.readbyqxmd.com/read/28440959/qualitative-research-in-teen-experiences-living-with-food-induced-anaphylaxis-a-meta-aggregation
#17
REVIEW
Sara F Johnson, Roberta L Woodgate
AIM: To describe the central experiences of teens living with Food-Induced Anaphylaxis as a first step in responding to health care needs in this population. BACKGROUND: As prevalence of allergy increases and commonly-outgrown allergies persist longer, chronic management for teens becomes increasingly important. This review seeks to understand how teens experience living with Food-Induced Anaphylaxis. DESIGN: Meta-aggregation for qualitative systematic review, to create synthesis for clinical improvement; guided by Joanna Briggs Institute methods and their Qualitative Assessment and Review Instrument...
April 25, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28439827/droplet-microfluidic-device-fabrication-and-use-for-isothermal-amplification-and-detection-of-microrna
#18
Maria Chiara Giuffrida, Roberta D'Agata, Giuseppe Spoto
Droplet microfluidics combined with the isothermal circular strand displacement polymerization (ICSDP) represents a powerful new technique to detect both single-stranded DNA and microRNA sequences. The method here described helps in overcoming some drawbacks of the lately introduced droplet polymerase chain reaction (PCR) amplification when implemented in microfluidic devices. The method also allows the detection of nanoliter droplets of nucleic acids sequences solutions, with a particular attention to microRNA sequences that are detected at the picomolar level...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28439727/barriers-to-information-provision-regarding-breast-cancer-and-its-treatment
#19
Heather J Campbell-Enns, Roberta L Woodgate, Harvey M Chochinov
PURPOSE: Women with breast cancer require information about their cancer and its treatment during the process of treatment decision-making, yet it is unclear if there are barriers to information support. This study explores the experience of making treatment decisions in breast cancer, paying particular attention to the barriers experienced to the provision of information. METHODS: Using a grounded theory methodology, semi-structured interviews were conducted with 22 women with invasive breast cancer exploring the experience of treatment decision-making...
April 24, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28438070/creation-of-a-novel-simulator-for-minimally-invasive-neurosurgery-fusion-of-3d-printing-and-special-effects
#20
Peter Weinstock, Roberta Rehder, Sanjay P Prabhu, Peter W Forbes, Christopher J Roussin, Alan R Cohen
OBJECTIVE Recent advances in optics and miniaturization have enabled the development of a growing number of minimally invasive procedures, yet innovative training methods for the use of these techniques remain lacking. Conventional teaching models, including cadavers and physical trainers as well as virtual reality platforms, are often expensive and ineffective. Newly developed 3D printing technologies can recreate patient-specific anatomy, but the stiffness of the materials limits fidelity to real-life surgical situations...
April 25, 2017: Journal of Neurosurgery. Pediatrics
keyword
keyword
63320
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"