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https://www.readbyqxmd.com/read/28340491/comparison-of-skillful-vs-less-skilled-young-soccer-players-on-anthropometric-maturation-physical-fitness-and-time-of-practice
#1
Márcio André de Gouvêa, Edilson Serpeloni Cyrino, João Valente-Dos-Santos, Alex Silva Ribeiro, Danilo Rodrigues Pereira da Silva, David Ohara, Manuel J Coelho-E-Silva, Enio Ricardo Vaz Ronque
This study compared maturation, body composition and physical fitness between youth soccer athletes with different technical skills levels. Sixty-two young athletes (11-17 years) were categorized dichotomously in more skilled (n=31) and less skilled (n=31) groups based on 3 specific technical tests (Dribbling Speed Test [DST], Shuttle Dribble Test [SDT] and Slalom Dribble Test [SLDT]). Chronological and skeletal age, time of practice, body composition and 4 physical fitness tests were performed for comparisons...
March 24, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/28340278/path-analysis-and-canonical-correlations-for-indirect-selection-of-jatropha-genotypes-with-higher-oil-yield
#2
L A Silva, L A Peixoto, P E Teodoro, E V Rodrigues, B G Laviola, L L Bhering
Jatropha is a species with great potential for biodiesel production, and the knowledge on how the main agronomic traits are correlated will contribute to its improvement. Therefore, the objectives of this study were to estimate the genetic parameters of the traits: plant height at 12 and 40 months, canopy projection on the row at 12 and 40 months, canopy projection between the row at 12 and 40 months, number of branches at 40 months, grain yield, and oil yield; to verify the existence of phenotypic correlation between these traits; to verify the influence of the morphological traits on oil yield by means of path analysis; and to evaluate the relationship between the productive traits in Jatropha and the morphological traits measured at different ages...
March 22, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28340276/multivariate-diallel-analysis-allows-multiple-gains-in-segregating-populations-for-agronomic-traits-in-jatropha
#3
P E Teodoro, E V Rodrigues, L A Peixoto, L A Silva, B G Laviola, L L Bhering
Jatropha is research target worldwide aimed at large-scale oil production for biodiesel and bio-kerosene. Its production potential is among 1200 and 1500 kg/ha of oil after the 4th year. This study aimed to estimate combining ability of Jatropha genotypes by multivariate diallel analysis to select parents and crosses that allow gains in important agronomic traits. We performed crosses in diallel complete genetic design (3 x 3) arranged in blocks with five replications and three plants per plot. The following traits were evaluated: plant height, stem diameter, canopy projection between rows, canopy projection on the line, number of branches, mass of hundred grains, and grain yield...
March 22, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28340056/neutrophil-derived-mitochondrial-dna-promotes-receptor-activator-of-nuclear-factor-%C3%AE%C2%BAb-and-its-ligand-signalling-in-rheumatoid-arthritis
#4
Anne Contis, Stéphane Mitrovic, Julie Lavie, Isabelle Douchet, Estibaliz Lazaro, Marie-Elise Truchetet, Cyril Goizet, Cécile Contin-Bordes, Thierry Schaeverbeke, Patrick Blanco, Rodrigue Rossignol, Benjamin Faustin, Christophe Richez, Pierre Duffau
Objectives.: Mitochondrial DNA (mtDNA) contains sequestered damage-associated molecular patterns that might be involved in osteoimmunological pathogenesis of RA. Here, we aimed to investigate the cellular source of mtDNA and its role in RANK ligand (RANKL) expression by RA SF neutrophils. Methods.: The gene expression signature of SF neutrophils was examined by proteomic quantitative analysis. Levels of mtDNA in circulating and SF neutrophils from RA patients and OA control subjects were assessed by real-time PCR...
March 13, 2017: Rheumatology
https://www.readbyqxmd.com/read/28339618/telomere-length-oxidative-stress-inflammation-and-bdnf-levels-in-siblings-of-patients-with-bipolar-disorder-implications-for-accelerated-cellular-aging
#5
Mirela Paiva Vasconcelos-Moreno, Gabriel Rodrigo Fries, Carolina Gubert, Bárbara Tietböhl Martins Quadros Dos Santos, Adam Fijtman, Juliana Sartori, Pamela Ferrari, Lucas Kich Grun, Mariana Migliorini Parisi, Fátima Theresinha Costa Rodrigues Guma, Florencia Maria Barbé-Tuana, Flávio Kapczinski, Adriane Ribeiro Rosa, Lakshmi N Yatham, Marcia Kauer-Sant'Anna
Background: Growing evidence supports the existence of neurobiological trait abnormalities in individuals at genetic risk for bipolar disorder. The aim of this study was to examine potential differences in brain-derived neurotrophic factor, cytokines, oxidative stress, and telomere length markers between patients with bipolar disorder, their siblings, and healthy controls. Methods: Thirty-six patients with bipolar disorder type I, 39 siblings, and 44 healthy controls were assessed...
January 30, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28338948/comparing-measured-and-calculated-doses-in-interventional-cardiology-procedures
#6
M W Oliveira da Silva, L V Canevaro, J Hunt, B B D Rodrigues
Interventional cardiology requires complex procedures and can result in high doses and dose rates to the patient and medical staff. The many variables that influence the dose to the patient and staff include the beam position and angle, beam size, kVp, filtration, kerma-area product and focus-skin distance. A number of studies using the Monte Carlo method have been undertaken to obtain prospective dose assessments. In this paper, detailed irradiation scenarios were simulated mathematically and the resulting dose estimates were compared with real measurements made previously under very similar irradiation conditions and geometries...
March 16, 2017: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/28337841/yeast-aquaporin-regulation-by-4-hydroxynonenal-is-implicated-in-oxidative-stress-response
#7
Claudia Rodrigues, Ivana Tartaro Bujak, Branka Mihaljević, Graça Soveral, Ana Cipak Gasparovic
Reactive oxygen species, especially hydrogen peroxide (H2 O2 ), contribute to functional molecular impairment and cellular damage, but also are necessary in normal cellular metabolism, and in low doses play stimulatory role in cell proliferation and stress resistance. In parallel, reactive aldehydes such as 4-hydroxynonenal (HNE), are lipid peroxidation breakdown products which also contribute to regulation of numerous cellular processes. Recently, channeling of H2 O2 by some mammalian aquaporin isoforms has been reported and suggested to contribute to aquaporin involvement in cancer malignancies, although the mechanism by which these membrane water channels are implicated in oxidative stress is not clear...
March 24, 2017: IUBMB Life
https://www.readbyqxmd.com/read/28336818/increased-exposure-to-sodium-during-pregnancy-and-lactation-changes-basal-and-induced-behavioral-and-neuroendocrine-responses-in-adult-male-offspring
#8
Marcia S Silva, Fabiana Lúcio-Oliveira, Andre Souza Mecawi, Lucas F Almeida, Silvia G Ruginsk, Michael P Greenwood, Mingkwan Greenwood, Laura Vivas, Lucila L K Elias, David Murphy, José Antunes-Rodrigues
Excessive sodium (Na(+)) intake in modern society has been associated with several chronic disorders such as hypertension. Several studies suggest that early life events can program physiological systems and lead to functional changes in adulthood. Therefore, we investigated behavioral and neuroendocrine responses under basal conditions and after 48 h of water deprivation in adult (60-day-old Wistar rats) male, Wistar rats originating from dams were offered only water or 0.15 mol/L NaCl during pregnancy and lactation...
March 2017: Physiological Reports
https://www.readbyqxmd.com/read/28336399/synthetic-matrix-of-polyether-polyurethane-as-a-biological-platform-for-pancreatic-regeneration
#9
Luciana Xavier Pereira, Celso Tarso Rodrigues Viana, Laura Alejandra Ariza Orellano, Simone Aparecida de Almeida, Anilton Cesar Vasconcelos, Alfredo de Miranda Goes, Alexander Birbrair, Silvia Passos Andrade, Paula Peixoto Campos
AIMS: Several alternative cellular approaches using biomaterials to host insulin-producing cells derived from stem cells have been developed to overcome the limitations of type 1 diabetes treatment (exogenous insulin injection). However, none seem to fulfill all requirements needed to induce pancreatic cells successful colonization of the scaffolds. Here, we report a polymeric platform adherent to the native mice pancreas filled with human adipose stem cells (hASCs) that was able to induce growth of pancreatic parenchyma...
March 20, 2017: Life Sciences
https://www.readbyqxmd.com/read/28336174/the-exposure-to-formaldehyde-causes-renal-dysfunction-inflammation-and-redox-imbalance-in-rats
#10
Camila de Oliveira Ramos, Clarissa Rodrigues Nardeli, Keila Karine Duarte Campos, Karina Braga Pena, Dafne Fernandes Machado, Ana Carla Balthar Bandeira, Guilherme de Paula Costa, André Talvani, Frank Silva Bezerra
Twenty-eight Fischer male rats were divided into four groups: control group (CG), exposed to the ambient air, and groups exposed to formaldehyde (FA) at concentrations of 1% (FA1%), 5% (FA5%) and 10% (FA10%). Kidney function was assessed by dosage of uric acid, creatinine and urea. Morphometry was performed on the thickness of the lumen of Bowman's capsule and diameter of the lumen of the renal tubules. We evaluated the redox imbalance through the catalase and superoxide dismutase activity as well as oxidative damage by lipid peroxidation...
March 20, 2017: Experimental and Toxicologic Pathology: Official Journal of the Gesellschaft Für Toxikologische Pathologie
https://www.readbyqxmd.com/read/28334957/quechers-based-method-for-pesticides-analysis-in-adipose-tissue-associated-with-rat-ovaries
#11
Nathalie Zamariola, Pedro Toledo Netto, Carla Adriene da Silva Franchi, João Lauro Viana de Camargo, Mary Rosa Rodrigues de Marchi
The concomitant exposure to low doses of various pesticides is one of the most relevant issues in human toxicology today. An experimental toxicology study was developed to evaluate the effects of this type of exposure on the reproductive capacity of females of three species of rats that were exposed to mixtures of dicofol, dieldrin, endosulfan and permethrin at low doses (LOAEL and NOAEL). In this context, we have developed a method for determining pesticides in adipose tissue (0.5 g, 49% lipid) associated with the ovaries, based on the QuEChERS (quick, easy, cheap, effective, rugged and safe) strategy...
March 14, 2017: Journal of Analytical Toxicology
https://www.readbyqxmd.com/read/28334938/clinical-and-genetic-characterization-of-leukoencephalopathies-in-adults
#12
David S Lynch, Anderson Rodrigues Brandão de Paiva, Wei Jia Zhang, Enrico Bugiardini, Fernando Freua, Leandro Tavares Lucato, Lucia Inês Macedo-Souza, Rahul Lakshmanan, Justin A Kinsella, Aine Merwick, Alexander M Rossor, Nin Bajaj, Brian Herron, Paul McMonagle, Patrick J Morrison, Deborah Hughes, Alan Pittman, Matilde Laurà, Mary M Reilly, Jason D Warren, Catherine J Mummery, Jonathan M Schott, Matthew Adams, Nick C Fox, Elaine Murphy, Indran Davagnanam, Fernando Kok, Jeremy Chataway, Henry Houlden
Leukodystrophies and genetic leukoencephalopathies are a rare group of disorders leading to progressive degeneration of cerebral white matter. They are associated with a spectrum of clinical phenotypes dominated by dementia, psychiatric changes, movement disorders and upper motor neuron signs. Mutations in at least 60 genes can lead to leukoencephalopathy with often overlapping clinical and radiological presentations. For these reasons, patients with genetic leukoencephalopathies often endure a long diagnostic odyssey before receiving a definitive diagnosis or may receive no diagnosis at all...
March 2, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28334779/targeted-gene-knock-in-by-homology-directed-genome-editing-using-cas9-ribonucleoprotein-and-aav-donor-delivery
#13
Thomas Gaj, Brett T Staahl, Gonçalo M C Rodrigues, Prajit Limsirichai, Freja K Ekman, Jennifer A Doudna, David V Schaffer
Realizing the full potential of genome editing requires the development of efficient and broadly applicable methods for delivering programmable nucleases and donor templates for homology-directed repair (HDR). The RNA-guided Cas9 endonuclease can be introduced into cells as a purified protein in complex with a single guide RNA (sgRNA). Such ribonucleoproteins (RNPs) can facilitate the high-fidelity introduction of single-base substitutions via HDR following co-delivery with a single-stranded DNA oligonucleotide...
March 2, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28334069/standardized-sampling-plan-for-the-thrips-frankliniella-schultzei-thysanoptera-thripidae-on-watermelon-crops
#14
Cleovan Barbosa Pinto, Renato Almeida Sarmento, Tarcísio Visintin da Silva Galdino, Poliana Silvestre Pereira, Breno Gomes Barbosa, Carlos Henrique Oliveira Lima, Nilson Rodrigues da Silva, Marcelo Coutinho Picanço
Sampling plans are essential components of integrated pest management programs. The thrips Frankliniella schultzei (Trybom) (Thysanoptera: Thripidae) is an important pest of watermelon crops. Despite the importance of sampling plans and of F. schultzei as a pest of watermelon crops, no research has been previously conducted on this subject for this crop. The objective of this work was to create a standardized sampling plan for F. schultzei in watermelon crops. Over two consecutive years, weekly samplings were performed in commercial watermelon crops...
February 11, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/28334068/the-dyslexia-susceptibility-protein-kiaa0319-inhibits-axon-growth-through-smad2-signaling
#15
Filipa Franquinho, Joana Nogueira-Rodrigues, Joana M Duarte, Sofia S Esteves, Christin Carter-Su, Anthony P Monaco, Zoltán Molnár, Antonio Velayos-Baeza, Pedro Brites, Mónica M Sousa
KIAA0319 is a transmembrane protein associated with dyslexia with a presumed role in neuronal migration. Here we show that KIAA0319 expression is not restricted to the brain but also occurs in sensory and spinal cord neurons, increasing from early postnatal stages to adulthood and being downregulated by injury. This suggested that KIAA0319 participates in functions unrelated to neuronal migration. Supporting this hypothesis, overexpression of KIAA0319 repressed axon growth in hippocampal and dorsal root ganglia neurons; the intracellular domain of KIAA0319 was sufficient to elicit this effect...
February 17, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28333989/street-trees-reduce-the-negative-effects-of-urbanization-on-birds
#16
João Carlos de Castro Pena, Felipe Martello, Milton Cezar Ribeiro, Richard A Armitage, Robert J Young, Marcos Rodrigues
The effects of streets on biodiversity is an important aspect of urban ecology, but it has been neglected worldwide. Several vegetation attributes (e.g. street tree density and diversity) have important effects on biodiversity and ecological processes. In this study, we evaluated the influences of urban vegetation-represented by characteristics of street trees (canopy size, proportion of native tree species and tree species richness)-and characteristics of the landscape (distance to parks and vegetation quantity), and human impacts (human population size and exposure to noise) on taxonomic data and functional diversity indices of the bird community inhabiting streets...
2017: PloS One
https://www.readbyqxmd.com/read/28333926/performance-of-tci-tcvi-tcii-chagas-flow-ate-igg2a-for-universal-and-genotype-specific-serodiagnosis-of-trypanosoma-cruzi-infection
#17
Glaucia Diniz Alessio, Fernanda Fortes de Araújo, Denise Fonseca Côrtes, Policarpo Ademar Sales Júnior, Daniela Cristina Lima, Matheus de Souza Gomes, Laurence Rodrigues do Amaral, Marcelo Antônio Pascoal Xavier, Andréa Teixeira-Carvalho, Olindo Assis Martins-Filho, Marta de Lana
Distinct Trypanosoma cruzi genotypes have been considered relevant for patient management and therapeutic response Chagas disease. However, typing strategies for genotype-specific serodiagnosis of Chagas disease are still unavailable and requires standardization for practical application. In this study, an innovative TcI/TcVI/TcII Chagas Flow ATE-IgG2a technique was developed with applicability for universal and genotype-specific diagnosis of T. cruzi infection. For this purpose, the reactivity of serum samples (percentage of positive fluorescent parasites-PPFP) obtained from mice chronically infected with TcI/Colombiana, TcVI/CL or TcII/Y strain as well as non-infected controls were determined using amastigote-AMA, trypomastigote-TRYPO and epimastigote-EPI in parallel batches of TcI, TcVI and TcII target antigens...
March 23, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28333173/functional-and-volumetric-analysis-of-the-pectoralis-major-muscle-after-submuscular-breast-augmentation
#18
Ana Claudia Roxo, Fabio Xerfan Nahas, Nadia Cristina Pinheiro Rodrigues, José Inácio Salles, Victor Rodrigues Amaral Cossich, Claudio Cardoso de Castro, Jose Horacio Aboudib, Ruy Garcia Marques
Background: Dual plane breast augmentation is a technical variation of the submuscular plane described as a technique that reduces contour deformities due to contraction of the pectoralis major muscle and lower risk of double-bubble deformity associated with breast ptosis. Despite improvement in the aesthetic aspect, there is still no consensus whether this technique affects the function of the pectoralis major muscle. Objectives: The aim of this study was to correlate functional with volumetric changes associated with dissection of the muscle origin in submuscular breast augmentation...
January 20, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28332902/caloric-restriction-minimizes-aging-effects-on-the-femoral-medial-condyle
#19
Renata Gabriel Fontinele, Walter Krause Neto, Eliane Florencio Gama, Renata de Brito Mari, Romeu Rodrigues de Souza, André Conrado, Luis Mochizuki, José Roberto Kfoury Junior
This study aimed to analyze the effects of caloric restriction on aged femoral articular cartilage of Wistar rats. Three groups of eight animals each were considered: young (YC) and old (OC) control groups fed with a normal diet and old caloric restriction group (OCR) composed of 18-month-old animals fed with a 31% less caloric diet from 6-months of age. Articular cartilage was studied through morphometry and immunohistochemistry. Body mass was 12% less in the OCR group than in the OC group. The articular cartilage from OC rats show thinner medial condyles, fewer chondrocytes, smaller chondrocytes nuclear volume and, in both condyles, a predominance of collagen type II and less collagen density compared to both YC and OCR groups (p < ...
March 23, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28332703/predictors-of-meaningful-improvement-in-quality-of-life-after-temporal-lobe-epilepsy-surgery-a-prospective-study
#20
Carla Pauli, Marcelo Liborio Schwarzbold, Alexandre Paim Diaz, Maria Emilia Rodrigues de Oliveira Thais, Charles Kondageski, Marcelo Neves Linhares, Ricardo Guarnieri, Bianca de Lemos Zingano, Juliana Ben, Jean Costa Nunes, Hans Joachim Markowitsch, Peter Wolf, Samuel Wiebe, Katia Lin, Roger Walz
OBJECTIVES: To investigate prospectively the independent predictors of a minimum clinically important change (MCIC) in quality of life (QOL) after anterior temporal lobectomy (ATL) for drug-resistant mesial temporal lobe epilepsy related to hippocampal sclerosis (MTLE-HS) in Brazilian patients. METHODS: Multiple binary logistic regression analysis was performed to identify the clinical, demographic, radiologic, and electrophysiologic variables independently associated with MCIC in the Quality of Life in Epilepsy-31 Inventory (QOLIE-31) overall score 1 year after ATL in 77 consecutive patients with unilateral MTLE-HS...
March 23, 2017: Epilepsia
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