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pleomorphic adenoma

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https://www.readbyqxmd.com/read/29771093/-pharyngeal-space-carcinoma-ex-pleomorphic-adenoma%C3%AF-a-case-report
#1
Y L Jiang, H S Peng, S H Wu, X H Xie, X H Zhu, Y H Liu
Carcinoma ex pleomorphic adenoma is an epithelial malignant tumor of pleomorphic adenoma. This may be due to the accumulation of genetic instability caused by long-term pleomorphic adenomas. There are few reports of parapharyngeal space carcinoma ex pleomorphic adenoma in the literature study both at home and abroad. This article retrospectively summarized the clinical data of 1 case of pharyngeal space carcinoma ex pleomorphic adenoma and reviewed the literature. We strengthened the understanding of parapharyngeal space carcinoma ex pleomorphic adenoma, improve the accuracy of diagnosis and reduce misdiagnosis and mistreatment...
May 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29765822/minimally-invasive-surgery-for-resection-of-parapharyngeal-space-tumors
#2
Irit Duek, Gill E Sviri, Salem Billan, Ziv Gil
Background  Surgical removal of parapharyngeal space tumors (PPST) poses challenges due to the complex anatomy of the region. PPSTs are routinely resected by a transcervical approach using blind finger dissection. Large PPSTs or those located high at the skull base, often require transmandibular or infratemporal fossa approaches, associated with considerable morbidity. Objective  Here, we describe an approach for PPST removal that comprises transcervical endoscopic, with or without transoral robotic technique...
June 2018: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/29764037/-the-value-of-high-resolution-diffusion-weighted-imaging-in-differentiating-benign-and-malignant-epithelial-tumors-of-parotid-gland
#3
B H Wen, J L Cheng, H X Zhang, Z X Zhang, F F Wang, K K Xue
Objective: To investigate the diagnostic value of RESOLVE DWI in the evaluation of benign and malignant epithelial tumors of parotid gland. Methods: A total of 106 patients in the First Affiliated Hospital of Zhengzhou University with epithelial tumors of parotid gland confirmed by pathology from July 2015 to October 2017 were retrospectively analyzed. All patients underwent preoperative routine MRI and RESOLVE DWI, the ADC average values were calculated, t test were used to compare the ADC values of benign and malignant epithelial tumors of parotid gland...
May 8, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29763370/novel-interleukin-33-and-its-soluble-st2-receptor-as-potential-serum-biomarkers-in-parotid-gland-tumors
#4
Sowa Pawel, Misiolek Maciej, Zielinski Maciej, Mazur Bogdan, Adamczyk-Sowa Monika
An increasing number of patients with parotid gland tumors have been observed in recent years. The relationship between the immune system and tumor formation is thoroughly investigated. However, newly discovered molecules offer a new insight into the pathophysiology of malignancies. It would be ideal to find an easily determinable biomarker of tumor existence, its malignant potential or a biomarker suggesting the probability of disease recurrence. Our study is the first to examine serum concentrations of IL-33 and its sST2 receptor in patients with various types of parotid gland tumors...
May 2018: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/29756618/intraparotid-facial-nerve-schwannoma-two-case-reports-and-a-review-of-the-literature
#5
M Simone, E Vesperini, C Viti, A Camaioni, L Lepanto, F Raso
Schwannomas are rare benign tumours that arise from Schwann cells. The most known and studied is the intracranial vestibular schwannoma, even if it is not the most frequent. More often schwannomas arise from peripheral sensitive nerves, and the vagous is most involved among the cranial nerves. Intraparotid schwannomas account for just 10% of all facial involvement, so they are an extremely rare localisation. At present, there are less than 100 cases described in the literature. We performed a retrospective analysis of parotidectomy in two Italian hospitals and present two cases of intraparotid schwannoma and a review of the literature...
February 2018: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/29755265/pleomorphic-adenoma-of-the-lacrimal-gland-a-review-with-updates-on-malignant-transformation-and-molecular-genetics
#6
REVIEW
William Harrison, Patricia Pittman, Thomas Cummings
Pleomorphic adenoma (benign mixed tumor) is the most common epithelial neoplasm of the lacrimal gland. It is usually a slow growing, well-circumscribed, mass that is identical to its salivary gland counterpart. Patients generally have an excellent prognosis for vision and long-term survival after complete surgical excision. There is a tendency to reoccur, especially if there is an incomplete excision, and rarely, malignant transformation to carcinoma ex pleomorphic adenoma can occur, which has a much poorer prognosis...
January 2018: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/29745753/does-acoustic-radiation-force-elastography-improve-the-diagnostic-capability-of-ultrasound-in-the-preoperative-characterization-of-masses-of-the-parotid-gland
#7
Pamela Zengel, Florian Notter, Dirk Andre Clevert
OBJECTIVES: Ultrasound is the method of choice for preoperative evaluation of tumors of the parotid glands. However, existing methods do not allow for clear differentiation between the most common benign tumors and malignant tumors. The aim of our study was to evaluate if acoustic radiation force, Virtual Touch Quantification (VTQ) elastography helps to improve the preoperative evaluation of parotid masses. METHODS: We investigated the parenchyma of 102 parotid glands, fourteen lymph nodes of healthy volunteers and 51 tumors of the parotid gland via ultrasound, color Doppler ultrasound and VTQ...
May 10, 2018: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/29725854/metastasising-pleomorphic-salivary-adenoma-a-rare-case-report-of-a-massive-untreated-minor-salivary-gland-pleomorphic-adenoma-with-concurrent-ipsilateral-cervical-node-metastases
#8
Melanie Watson, Peter McAllister, Brendan Conn, Morna MacNeill, Thomas P B Handley
Salivary gland tumours constitute approximately 1-5% of all human neoplasms. Pleomorphic adenoma (PA) is the commonest benign neoplasm affecting the parotid gland most often (> 75%), followed by the submandibular gland (13%), then the palate (9%). Metastasising pleomorphic adenoma (MPA) is extremely rare. The effects can be severe and a reported 40% of MPA patients die with disease. This case represents the first known case in English literature of an untreated minor salivary gland PSA of the palate metastasising to an ipsilateral cervical node...
May 3, 2018: Head and Neck Pathology
https://www.readbyqxmd.com/read/29723867/preoperative-diagnosis-of-neoplastic-or-malignant-h%C3%A3-rthle-cell-lesions-a-chimera
#9
Cristina Díaz Del Arco, M Jesús Fernández Aceñero
OBJECTIVE: We aimed to review all cytological specimens with Hürthle cells (HC) diagnosed in our institution, identify cytological features related to neoplastic (adenoma or carcinoma) and malignant histology, and discuss the role of clinicopathological findings and clinical management in these cases. STUDY DESIGN: We included 359 thyroid fine-needle aspiration cytology cases in our study. We reviewed the clinical and cytological features of surgical cases and correlated them with histological diagnosis...
May 3, 2018: Acta Cytologica
https://www.readbyqxmd.com/read/29723435/impact-on-clinical-follow-up-of-the-milan-system-for-salivary-gland-cytology-a-comparison-with-a-traditional-diagnostic-classification
#10
Lester J Layfield, Zubair Baloch, Sharon L Hirschowitz, Esther D Rossi
OBJECTIVE: No universally accepted classification exists for salivary gland fine-needle aspiration (FNA). The proposed Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) offers a uniform classification with management recommendations. We compared FNA diagnoses from a prior study with specific diagnoses with corresponding MSRSGC diagnoses. METHODS: One-hundred and sixty-four cases from a prior cytologic study with histologic follow-up were re-reviewed by one of the authors and assigned to one of the MSRSGC categories...
May 3, 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29715449/superficial-parotidectomy-versus-partial-superficial-parotidectomy-a-comparison-of-complication-rates-operative-time-and-hospital-stay
#11
Ahmet Erdem Kilavuz, Murat Songu, Ercan Pinar, Yilmaz Ozkul, Sedat Ozturkcan, Ibrahim Aladag
PURPOSE: The type and extent of surgery for benign parotid tumors are a subject of debate. We aimed to measure and compare hospital stay, operative time, and complication rates associated with superficial parotidectomy (SP) and partial superficial parotidectomy (PSP). MATERIALS AND METHODS: This retrospective cohort study included all patients who underwent surgery for benign parotid gland tumors in our tertiary center between January 2006 and March 2014 and were followed up for at least 3 years...
April 7, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29691554/-retrospective-analysis-of-896-cases-of-parotid-gland-tumor
#12
Zhi-Guo Zhao, Dan Gao, Jin Wang, Li-Ping Zhang
PURPOSE: To review the clinical data of patients undergoing operation, in order to summarize the incidence, proportion, clinical examination and diagnostic methods of parotid tumors. METHODS: Eight hundred and ninty-six cases of parotid gland tumors were collected from 2008 January to 2015 July from department of oral and maxillofacial surgery in Shengjing Hospital of China Medical University. A retrospective study of the clinical data was carried out, including age, gender, tumor location, diagnostic methods and pathological results...
December 2017: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/29689463/submandibular-gland-pleomorphic-adenoma-histopathological-capsular-characteristics-and-correlation-with-the-surgical-outcome
#13
Konstantinos Mantsopoulos, Miguel Goncalves, Michael Koch, Heinrich Iro, Abbas Agaimy
Pleomorphic adenoma (PA) of the submandibular gland is known to have a very low recurrence rate. The aim of this study was to investigate the histopathological and capsular characteristics of submandibular gland PA, looking for any differences between submandibular PA and the reported data for PA of the parotid gland as possible explanation for its low recurrence rate. We reviewed 72 submandibular gland PAs resected at our center between 2000 and 2016. Patient age ranged from 14 to 77 years (mean, 47.2). At least follow (range, 12 to 170 months; mean, 82), none of the 72 patients developed a local recurrence...
April 18, 2018: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/29680804/lacrimal-gland-pleomorphic-adenoma-and-malignant-epithelial-tumours-clinical-and-imaging-differences
#14
Stephanie Ming Young, Yoon-Duck Kim, Hyun Jin Shin, Yukihiro Imagawa, Stephanie S Lang, Kyung In Woo
AIMS: To investigate the clinical and imaging features of primary and recurrent lacrimal gland pleomorphic adenoma (LGPA), as well as lacrimal gland malignant epithelial tumours (LGMET). METHODS: Retrospective comparative case series from September 2000 to September 2016 in a single tertiary institution. Medical records of cases with histopathologically proven primary LGPA (PLGPA), recurrent LGPA (RLGPA) and LGMET were reviewed. RESULTS: Sixty-four patients with LGPA (55 primary and nine recurrent) and 36 patients with LGMET underwent surgical excision in the study period...
April 21, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29671211/characterisation-of-dog-1-expression-in-salivary-gland-tumours-and-comparison-with-myoepithelial-markers
#15
Syed A Khurram, Paul M Speight
DOG1 is an established diagnostic marker for gastrointestinal stromal tumours (GIST), but has been reported in salivary gland tumours (SGT) as an acinar and intercalated duct marker. However, its specificity and distribution is not well established. The aim of this study was to evaluate the diagnostic utility of DOG-1 expression in SGT in addition to comparing it with myoepithelial markers. Normal salivary tissue and SGT (n = 184) were examined for expression of DOG1 and a range of myoepithelial markers...
April 18, 2018: Head and Neck Pathology
https://www.readbyqxmd.com/read/29669190/analysis-of-histologic-follow-up-and-risk-of-malignancy-for-salivary-gland-neoplasm-of-uncertain-malignant-potential-proposed-by-the-milan-system-for-reporting-salivary-gland-cytopathology
#16
Haiyan Liu, Clarissa Ljungren, Fan Lin, Matthew A Zarka, Longwen Chen
BACKGROUND: The Milan System for Reporting Salivary Gland Cytopathology is a tiered classification scheme that includes 6 diagnostic categories. Neoplasm, which is 1 of the 6 proposed categories, consists of benign neoplasm and neoplasm of uncertain malignant potential (NUMP). NUMP is reserved for a salivary gland neoplasm without clear distinction between benign and malignant. The objective of this study was to assess the risk of malignancy (ROM) of NUMP. METHODS: A retrospective analysis was conducted on 656 salivary gland fine-needle aspiration specimens from 2010 to 2016...
April 18, 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/29667889/journal-club-the-warthin-tumor-score-a-simple-and-reliable-method-to-distinguish-warthin-tumors-from-pleomorphic-adenomas-and-carcinomas
#17
Chih-Wei Wang, Yueng-Hsiang Chu, Deng-Yiv Chiu, Nieh Shin, Hsian-He Hsu, Jih-Chin Lee, Chun-Jung Juan
OBJECTIVE: The objective of this article is to propose a Warthin tumor (WT) score to distinguish WTs from other parotid tumors. MATERIALS AND METHODS: The study included 78 patients with 92 histologically proven parotid tumors, including 42 WTs, 30 pleomorphic adenomas (PMAs), and 20 carcinomas. Echo-planar DW images were acquired. The WT score, which comprised the mean apparent diffusion coefficient (ADCM ) and the SD of the ADC (ADCSD ) of tumors, patient age, and patient sex, was used to predict WTs...
April 18, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29656683/clinicopathologic-analysis-of-2736-salivary-gland-cases-over-a-11-year-period-in-southwest-china
#18
S Y Shen, W H Wang, R Liang, G Q Pan, Y M Qian
OBJECTIVE: To investigate the epidemiological and clinicopathological characteristics of salivary gland tumors in southwest China in order to provide data for clinical diagnosis and other similar research. METHODS: Between March 2007 and December 2017, 2736 patients with salivary gland tumors were recruited, the clinical and pathological data were retrospectively analyzed. RESULTS: A total of 2736 patients had a ratio of males to females of about 1...
April 14, 2018: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29651432/oxidative-stress-markers-patients-with-parotid-gland-tumors-a-pilot-study
#19
Pawel Sowa, Maciej Misiolek, Bartlomiej Pasinski, Grzegorz Bartosz, Miroslaw Soszynski, Monika Adamczyk-Sowa, Izabela Sadowska-Bartosz
Salivary gland tumors account for 3-6% of tumors of the head and neck. About 80% of salivary gland tumors occur in parotid glands. Oxidative stress (OS) is implicated in the origin, development, and whole-body effects of various tumors. There are no data on the occurrence of OS in the parotid gland tumors. The aim of this study was to ascertain if whole-body OS accompanies parotid gland tumors, based first of all on oxidative modifications of blood serum proteins and other markers of OS in the serum of the patients...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29623392/clinical-utility-of-dynamic-enhanced-mri-in-salivary-gland-tumors-retrospective-study-and-literature-review
#20
Takenori Ogawa, Ikuho Kojima, Ryo Ishii, Maya Sakamoto, Takaki Murata, Takahiro Suzuki, Kengo Kato, Ayako Nakanome, Akira Ohkoshi, Eiichi Ishida, Seiji Kakehata, Kiyoto Shiga, Yukio Katori
PURPOSE: To improve the diagnoses of the salivary gland tumors, a dynamic-enhanced MRI (dMRI) was investigated. METHODS: We conducted a retrospective chart review of 93 cases of salivary gland tumors. The histological diagnoses were obtained from all patients using a surgical specimen and/or an open biopsy specimen. The dMRI as well as fine-needle aspiration cytology (FNAC) and intraoperative frozen section (IFS) were analyzed. This study focused on the time-intensity curve (TIC) after injection, peak time (Tpeak), washout ratio (WR) as well as the gradient of enhancement and washout profile...
April 6, 2018: European Archives of Oto-rhino-laryngology
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