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https://www.readbyqxmd.com/read/28636405/conventional-polysomnography-is-not-necessary-for-the-management-of-most-patients-with-suspected-obstructive-sleep-apnea
#1
Jaime Corral, Maria-Ángeles Sánchez-Quiroga, Carmen Carmona-Bernal, Ángeles Sánchez-Armengol, Alicia Sánchez-de-la-Torre, Joaquín Durán-Cantolla, Carlos J Egea, Neus Salord, Carmen Monasterio, Joaquín Terán, M Luz Alonso-Alvarez, Jesús Muñoz-Méndez, Eva M Arias, Marta Cabello, Josep M Montserrat, Mónica De la Peña, José C Serrano, Ferran Barbe, Juan F Masa
RATIONALE: Home respiratory polygraphy may be a simpler alternative to in-laboratory polysomnography for the management of more symptomatic obstructive sleep apnea patients, but its effectiveness has not been evaluated across a broad clinical spectrum. OBJECTIVE: To compare the long-term effectiveness (6 months) of home respiratory polygraphy and polysomnography management protocols in patients with intermediate to high sleep apnea suspicion (most patients requiring a sleep study)...
June 21, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28633722/characterization-of-patients-who-present-with-insomnia-is-there-room-for-asymptom-cluster-based-approach
#2
Megan R Crawford, Diana A Chirinos, Toni Iurcotta, Jack D Edinger, James K Wyatt, Rachel Manber, Jason C Ong
STUDY OBJECTIVES: This study examined empirically derived symptom cluster profiles among patients who present with insomnia using clinical data andpolysomnography. METHODS: Latent profile analysis was used to identify symptom cluster profiles of 175 individuals (63% female) with insomnia disorder based on total scoreson validated self-report instruments of daytime and nighttime symptoms (Insomnia Severity Index, Glasgow Sleep Effort Scale, Fatigue Severity Scale,Beliefs and Attitudes about Sleep, Epworth Sleepiness Scale, Pre-Sleep Arousal Scale), mean values from a 7-day sleep diary (sleep onset latency, wakeafter sleep onset, and sleep efficiency), and total sleep time derived from an in-laboratory PSG...
June 16, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28633720/evaluation-of-continuous-negative-external-pressure-cnep-for-the-treatment-of-obstructive-sleep-apnea-a-pilot-study
#3
Jerrold A Kram, Robyn V Woidtke, Kenneth B Klein, Richard M Rose
STUDY OBJECTIVES: To determine if the application of continuous negative external pressure (cNEP) is effective and safe in individuals with obstructive sleep apnea (OSA) during an overnight in-laboratory sleep study. METHODS: A prospective, open-label pilot study in subjects with documented OSA recruited from the patient population at one sleep clinic. The intervention was application and titration of cNEP during overnight polysomnography. RESULTS: Of the 15 subjects studied (mean apnea-hypopnea index [AHI] at baseline, 43...
June 16, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28633091/cyclic-alternating-pattern-and-interictal-epileptiform-discharges-during-morning-sleep-after-sleep-deprivation-in-temporal-lobe-epilepsy
#4
Filippo Sean Giorgi, Michelangelo Maestri, Melania Guida, Luca Carnicelli, Lorenzo Caciagli, Raffaele Ferri, Ubaldo Bonuccelli, Enrica Bonanni
PURPOSE: Sleep deprivation (SD) increases the occurrence of interictal epileptiform discharges (IED) compared to basal EEG in temporal lobe epilepsy (TLE). In adults, EEG after SD is usually performed in the morning after SD. We aimed to evaluate whether morning sleep after SD bears additional IED-inducing effects compared with nocturnal physiological sleep, and whether changes in sleep stability (described by the cyclic alternating pattern-CAP) play a significant role. METHODS: Adult patients with TLE underwent in-lab night polysomnography (n-PSG) and, within 7days from n-PSG, they underwent also a morning EEG after night SD (SD-EEG)...
June 17, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28630378/randomised-controlled-trial-of-the-efficacy-of-a-blue-enriched-light-intervention-to-improve-alertness-and-performance-in-night-shift-workers
#5
Tracey L Sletten, Suzanne Ftouni, Christian L Nicholas, Michelle Magee, Ronald R Grunstein, Sally Ferguson, David J Kennaway, Darren O'Brien, Steven W Lockley, Shantha M W Rajaratnam
OBJECTIVES: Night workers often experience high levels of sleepiness due to misalignment of the sleep-wake cycle from the circadian pacemaker, in addition to acute and chronic sleep loss. Exposure to light, in particular short wavelength light, can improve alertness and neurobehavioural performance. This randomised controlled trial examined the efficacy of blue-enriched polychromatic light to improve alertness and neurobehavioural performance in night workers. DESIGN: Participants were 71 night shift workers (42 males; 32...
June 19, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28625231/you-ll-feel-better-in-the-morning-slow-wave-activity-and-overnight-mood-regulation-in-interepisode-bipolar-disorder
#6
A M Soehner, K A Kaplan, J M Saletin, L S Talbot, I S Hairston, J Gruber, P Eidelman, M P Walker, A G Harvey
BACKGROUND: Sleep disturbances are prominent correlates of acute mood episodes and inadequate recovery in bipolar disorder (BD), yet the mechanistic relationship between sleep physiology and mood remains poorly understood. Using a series of pre-sleep mood inductions and overnight sleep recording, this study examined the relationship between overnight mood regulation and a marker of sleep intensity (non-rapid eye movement sleep slow wave activity; NREM SWA) during the interepisode phase of BD...
June 19, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28620158/clinical-features-and-sleep-analysis-of-chinese-patients-with-fatal-familial-insomnia
#7
Liyong Wu, Hui Lu, Xianling Wang, Jia Liu, Chaoyang Huang, Jing Ye, Cuijiang Li, Jun Lu, Yuping Wang, Jianping Jia, Shuqin Zhan
This study aimed to examine clinical features, sleep, abnormal sleep-wake transition and non-sleep disturbances as well as lab tests in Chinese fatal familial insomnia (FFI) subjects. Patients with confirmed clinical and laboratory diagnosis of FFI have been retrospectively reviewed. The clinical features and the results of the complementary tests, including polysomnography (PSG), brain imaging and genetic analysis, were used. Two male and three female patients were recruited in this study. Three of the five patients had more comprehensive family medical records...
June 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28613222/laboratory-evaluation-of-hypercoagulable-states-in-patients-with-central-retinal-vein-occlusion-who-are-less-than-56-years-of-age
#8
Qingyun Liu, J Michael Lahey, Rachel Karlen, Jay M Stewart
PURPOSE: To investigate whether the results of early tests for hypercoagulability are correlated with the development of central retinal vein occlusion risk factors later in life and to evaluate the necessity of these tests in younger patients. METHODS: This was a retrospective, observational case series. From January 1995 to December 2014, 55 patients aged below 56 years with central retinal vein occlusion (CRVO) were enrolled in the study. Laboratory evaluations for homocysteine, activated protein C resistance, protein C activity, protein S activity, antithrombin III activity, antiphospholipid antibodies, and anticardiolipin antibodies were obtained at the onset of CRVO...
April 24, 2017: Retina
https://www.readbyqxmd.com/read/28599531/physiological-effects-of-railway-vibration-and-noise-on-sleep
#9
Michael G Smith, Ilona Croy, Mikael Ögren, Oscar Hammar, Eva Lindberg, Kerstin Persson Waye
This paper evaluates the relative contribution of vibration and noise from railway on physiological sleep outcomes. Vibration from railway freight often accompanies airborne noise, yet is almost totally absent in the existing literature. In an experimental investigation, 23 participants, each sleeping for six nights in the laboratory, were exposed to 36 simulated railway freight pass-bys per night with vibration alone (aWd,max = 0.0204 ms(-2)), noise alone (LAF,max = 49.8 dB), or both vibration and noise simultaneously...
May 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28598799/clinical-outcomes-of-an-inpatient-pediatric-obesity-treatment-program-in-the-usa
#10
Sharonda J Alston Taylor, Kimberly Rennie, Cindy Jon
Background When treating recalcitrant and severe childhood obesity, pharmaceutical options are limited and few patients qualify for bariatric surgery. A prolonged inpatient program serves as an alternative treatment. The purpose of this project was to describe the development of a medically supervised inpatient weight management program and evaluate its effectiveness. Methods This is a retrospective chart review of 18 patients [4-18 years, mean body mass index (BMI) 50.2 kg/m2] admitted to an inpatient pediatric weight management program from October 2011 through December 31, 2012 to evaluate the biometric, laboratory, sleep and behavioral changes that occurred from admission to discharge from the program...
June 9, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28596012/effects-of-positive-airway-pressure-therapy-on-cardiovascular-and-metabolic-markers-in-males-with-obstructive-sleep-apnea
#11
A Feliciano, M J Oliveira, A Cysneiros, C Martinho, R P Reis, D Penque, P Pinto, C Bárbara
INTRODUCTION: Obstructive sleep apnea syndrome (OSAS) is associated with cardiovascular/metabolic complications. Some analytical parameters (homocysteine, glycemic and lipidic profiles) are recognized markers of these consequences. Limited data is available on the association of these markers and OSAS's severity/response to positive airway pressure therapy (PAP). MATERIAL AND METHODS: In this prospective study we analyzed polysomnographic and analytical data of male patients admitted to sleep laboratory...
June 5, 2017: Revista Portuguesa de Pneumologia
https://www.readbyqxmd.com/read/28592453/diagnosis-and-management-of-dementia-with-lewy-bodies-fourth-consensus-report-of-the-dlb-consortium
#12
REVIEW
Ian G McKeith, Bradley F Boeve, Dennis W Dickson, Glenda Halliday, John-Paul Taylor, Daniel Weintraub, Dag Aarsland, James Galvin, Johannes Attems, Clive G Ballard, Ashley Bayston, Thomas G Beach, Frédéric Blanc, Nicolaas Bohnen, Laura Bonanni, Jose Bras, Patrick Brundin, David Burn, Alice Chen-Plotkin, John E Duda, Omar El-Agnaf, Howard Feldman, Tanis J Ferman, Dominic Ffytche, Hiroshige Fujishiro, Douglas Galasko, Jennifer G Goldman, Stephen N Gomperts, Neill R Graff-Radford, Lawrence S Honig, Alex Iranzo, Kejal Kantarci, Daniel Kaufer, Walter Kukull, Virginia M Y Lee, James B Leverenz, Simon Lewis, Carol Lippa, Angela Lunde, Mario Masellis, Eliezer Masliah, Pamela McLean, Brit Mollenhauer, Thomas J Montine, Emilio Moreno, Etsuro Mori, Melissa Murray, John T O'Brien, Sotoshi Orimo, Ronald B Postuma, Shankar Ramaswamy, Owen A Ross, David P Salmon, Andrew Singleton, Angela Taylor, Alan Thomas, Pietro Tiraboschi, Jon B Toledo, John Q Trojanowski, Debby Tsuang, Zuzana Walker, Masahito Yamada, Kenji Kosaka
The Dementia with Lewy Bodies (DLB) Consortium has refined its recommendations about the clinical and pathologic diagnosis of DLB, updating the previous report, which has been in widespread use for the last decade. The revised DLB consensus criteria now distinguish clearly between clinical features and diagnostic biomarkers, and give guidance about optimal methods to establish and interpret these. Substantial new information has been incorporated about previously reported aspects of DLB, with increased diagnostic weighting given to REM sleep behavior disorder and (123)iodine-metaiodobenzylguanidine (MIBG) myocardial scintigraphy...
June 7, 2017: Neurology
https://www.readbyqxmd.com/read/28590499/can-statistical-machine-learning-algorithms-help-for-classification-of-obstructive-sleep-apnea-severity-to-optimal-utilization-of-polysomnography-resources
#13
Selen Bozkurt, Asli Bostanci, Murat Turhan
OBJECTIVES: The goal of this study is to evaluate the results of machine learning methods for the classification of OSA severity of patients with suspected sleep disorder breathing as normal, mild, moderate and severe based on non-polysomnographic variables: 1) clinical data, 2) symptoms and 3) physical examination. METHODS: In order to produce classification models for OSA severity, five different machine learning methods (Bayesian network, Decision Tree, Random Forest, Neural Networks and Logistic Regression) were trained while relevant variables and their relationships were derived empirically from observed data...
June 7, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28586093/agreement-between-jaw-muscle-activity-measurement-with-portable-single-channel-electromyography-and-polysomnography-in-children
#14
Claudia Restrepo, Frank Lobbezoo, Eduardo Castrillon, Peter Svensson, Adriana Santamaria, Claudia Alvarez, Ruben Manrique, Daniele Manfredini
BACKGROUND: Polysomnography (PSG) is the gold standard for sleep bruxism (SB) assessment. High economical costs, complex technical equipment, and unfamiliar laboratory setting limit its use in children. AIM: To determine the night-to-night variability of electromyography (EMG) episodes during a five-night recording with the GrindCare Measure (GCM), and the agreement in the assessment of masticatory muscle activity (MMA) between GCM and PSG in children. DESIGN: Forty-seven children from clinics of Universidad CES participated...
June 6, 2017: International Journal of Paediatric Dentistry
https://www.readbyqxmd.com/read/28585737/a-new-measure-of-hallucinatory-states-and-a-discussion-of-rem-sleep-dreaming-as-a-virtual-laboratory-for-the-rehearsal-of-embodied-cognition
#15
Clemens Speth, Jana Speth
Hallucinatory states are experienced not only in connection with drugs and psychopathologies but occur naturally and spontaneously across the human circadian cycle: Our nightly dreams bring multimodal experiences in the absence of adequate external stimuli. The current study proposes a new, tighter measure of these hallucinatory states: Sleep onset, REM sleep, and non-REM sleep are shown to differ with regard to (a) motor imagery indicating interactions with a rich imaginative world, and (b) cognitive agency that could enable sleepers to recognize their hallucinatory state...
June 6, 2017: Cognitive Science
https://www.readbyqxmd.com/read/28583511/blood-count-values-and-ratios-for-predicting-sleep-apnea-in-obese-children
#16
Ibrahim Erdim, Omer Erdur, Fatih Oghan, Fatih Mete, Mustafa Celik
OBJECTIVES: To detect whether the mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) are contributing factors in the diagnosis and severity of sleep apnea in obese children. INTRODUCTION: Obesity is a public health problem, and its prevalence increases daily. Although PSG is the gold standard test in the investigation of sleep apnea, the application of this test requires equipment, personnel, time, and cost. There is no simple laboratory test for diagnosing and determining the severity of sleep apnea...
July 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28578930/meal-timing-regulates-the-human-circadian-system
#17
Sophie M T Wehrens, Skevoulla Christou, Cheryl Isherwood, Benita Middleton, Michelle A Gibbs, Simon N Archer, Debra J Skene, Jonathan D Johnston
Circadian rhythms, metabolism, and nutrition are intimately linked [1, 2], although effects of meal timing on the human circadian system are poorly understood. We investigated the effect of a 5-hr delay in meals on markers of the human master clock and multiple peripheral circadian rhythms. Ten healthy young men undertook a 13-day laboratory protocol. Three meals (breakfast, lunch, dinner) were given at 5-hr intervals, beginning either 0.5 (early) or 5.5 (late) hr after wake. Participants were acclimated to early meals and then switched to late meals for 6 days...
June 19, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28575467/arousability-and-fall-risk-during-forced-awakenings-from-nocturnal-sleep-among-healthy-males-following-administration-of-zolpidem-10-mg-and-doxepin-6-mg-a-randomized-placebo-controlled-four-way-crossover-trial
#18
Christopher L Drake, Heith Durrence, Philip Cheng, Thomas Roth, Vivek Pillai, Edward L Peterson, Meeta Singh, Kieulinh Michelle Tran
Study Objectives: To examine and compare the arousability threshold and fall risk upon awakening of doxepin (6 mg) versus zolpidem (10 mg). Methods: A total of 52 healthy adult males were included in a double-blind, placebo-controlled, 4-way crossover study. The experimental procedure included four nights with polysomnography in the lab (zolpidem, doxepin, and their respective placebo conditions). Arousability was measured using an auditory awakening threshold delivered at the peak-plasma concentration for the active hypnotics and at matched times for the respective placebo conditions...
June 1, 2017: Sleep
https://www.readbyqxmd.com/read/28572891/factors-positively-influencing-health-are-associated-with-a-lower-risk-of-development-of-metabolic-syndrome-in-korean-men-the-2007-2009-korean-national-health-and-nutrition-examination-survey
#19
Shinhye Kim, Mi-Ra Cho, Taejong Kim, Hyoung-Ji Lim, Jae Woo Lee, Hee-Taik Kang
BACKGROUND: The prevalence of metabolic syndrome (MetS) has risen rapidly worldwide, including in South Korea. Factors related to lifestyle are closely associated with the development of MetS. The aim of this study was to investigate the association between MetS and a number of factors positively influencing health, namely non-smoking, low-risk drinking, sufficient sleep, regular exercise, and the habit of reading food labels, among Korean men. METHODS: This cross-sectional study included 3,869 men from the 2007-2009 Korean National Health and Nutrition Examination Survey...
May 2017: Korean Journal of Family Medicine
https://www.readbyqxmd.com/read/28568911/dream-emotions-a-comparison-of-home-dream-reports-with-laboratory-early-and-late-rem-dream-reports
#20
Pilleriin Sikka, Antti Revonsuo, Nils Sandman, Jarno Tuominen, Katja Valli
The aim of this study was to compare the emotional content of dream reports collected at home upon morning awakenings with those collected in the laboratory upon early and late rapid eye movement (REM) sleep awakenings. Eighteen adults (11 women, seven men; mean age = 25.89 ± 4.85) wrote down their home dreams every morning immediately upon awakening during a 7-day period. Participants also spent two non-consecutive nights in the sleep laboratory where they were awoken 5 min into each continuous REM sleep stage, upon which they gave a verbal dream report...
June 1, 2017: Journal of Sleep Research
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