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sleep lab

Do Hyeon Yoo, Jaekook Lee, Chul Hee Min
The aim of this study is to develop the Effective Dose Calculation Program (EDCP) for the usage of Naturally Occurring Radioactive Material (NORM) added consumer products. The EDCP was developed based on a database of effective dose conversion coefficient and the Matrix Laboratory (MATLAB) program to incorporate a Graphic User Interface (GUI) for ease of use. To validate EDCP, the effective dose calculated with EDCP by manually determining the source region by using the GUI and that by using the reference mathematical algorithm were compared for pillow, waist supporter, eye-patch and sleeping mattress...
April 9, 2018: Applied Radiation and Isotopes
Aliza Rizwan, Abdulghani Sankari, Amy T Bascom, Sarah Vaughan, M Safwan Badr
Respiratory complications are potential causes of death in patients with spinal cord injury (SCI). Nocturnal swallowing could be related to transient arousals, and lead to fragmented sleep in SCI patients. However, the impact of nocturnal swallowing on breathing and sleep physiology in SCI is unknown. The objectives of this study were (1) to determine whether nocturnal swallowing is more common in SCI than in able-bodied subjects, (2) to determine the role of nocturnal swallowing on arousal threshold in SCI individuals with sleep-disordered breathing (SDB), (3) to determine the effect of CPAP treatment on nocturnal swallowing...
April 19, 2018: Journal of Applied Physiology
Lisa M Hernández, Rachel R Markwald, Shiloah A Kviatkovsky, Lori N Perry, Marcus K Taylor
Introduction: Accumulating evidence suggests that trends in salivary cortisol after awakening may be reliable biological predictors of morbidity and mortality. In a sample of elite military men, our lab recently established summary parameters of morning cortisol as well as their stability across 2 d of repeated sampling. Materials and Methods: In this follow-on study, we evaluated summary parameters and their relationships to theoretically relevant demographic (i...
April 6, 2018: Military Medicine
Margaret Haney, Ziva D Cooper, Gillinder Bedi, Evan Herrmann, Sandra D Comer, Stephanie Collins Reed, Richard W Foltin, Frances R Levin
The α2a-adrenergic agonist, lofexidine, reduced cannabis withdrawal-related sleep disruption in the laboratory, but side effects (e.g. fatigue, hypotension) limit its utility as a treatment for cannabis use disorder. This study tested the potential efficacy and tolerability of a daily bedtime administration of the FDA-approved α2a-adrenergic agonist, guanfacine, in a human laboratory model of cannabis use disorder. Daily, nontreatment-seeking cannabis smokers (13M, 2F) completed a within-subject study comprising two 9-day inpatient study phases...
April 16, 2018: Addiction Biology
Thomas Kröber, Konstantinos Koussis, Martine Bourquin, Panagiota Tsitoura, Maria Konstantopoulou, Taiwo Sam Awolola, Francesca R Dani, Huili Qiao, Paolo Pelosi, Kostas Iatrou, Patrick M Guerin
There is increasing interest in the development of effective mosquito repellents of natural origin to reduce transmission of diseases such as malaria and yellow fever. To achieve this we have employed an in vitro competition assay involving odorant-binding proteins (OBPs) of the malaria mosquito, Anopheles gambiae, with a predominantly female expression bias to identify plant essential oils (EOs) containing bioactive compounds that target mosquito olfactory function. EOs and their fractions capable of binding to such OBPs displayed repellence against female mosquitoes in a laboratory repellence assay...
April 12, 2018: Insect Biochemistry and Molecular Biology
Sarah Kölling, Rob Duffield, Daniel Erlacher, Ranel Venter, Shona L Halson
The body of research that reports the relevance of sleep in high-performance sports is growing steadily. While the identification of sleep cycles and diagnosis of sleep disorders is limited to lab-based assessment via polysomnography, the development of activity-based devices estimating sleep patterns provides greater insight into the sleep behaviour of athletes in ecological settings. Overall, small sleep quantity and/or poor quality appears to exist in many athletic populations, though this may be related to training and competition context...
April 13, 2018: International Journal of Sports Physiology and Performance
T Makiguchi, S Yokoo, J Kurihara
The aim of this study was to investigate risk factors for postoperative delirium in patients undergoing free flap reconstruction for defects after oral cancer resection. This was a non-randomized, retrospective cohort study involving 102 patients who underwent oral cancer resection and free flap reconstruction. Data were collected from the medical records. Postoperative delirium occurred in 34 patients (33.3%), of whom 27 were male and seven were female. High preoperative total protein and albumin, diabetes mellitus, history of smoking, use of hypnotics or antipsychotics, time until getting out of bed after surgery, and postoperative insomnia were significantly related to delirium in the univariate analysis (P<0...
April 10, 2018: International Journal of Oral and Maxillofacial Surgery
Chi-Fu Jeffrey Yang, Kelli Aibel, Ryan Meyerhoff, Frances Wang, David Harpole, Amy P Abernethy, Thomas W LeBlanc
OBJECTIVES: Patients receiving induction chemotherapy for acute myeloid leukaemia (AML) anecdotally describe poor sleep, but sleep disturbances have not been well-characterised in this population. We aimed to test the feasibility of measuring sleep quality in AML inpatients using a wearable actigraphy device. METHODS: Using the Actigraph GT3X 'watch', we assessed the total sleep time, sleep onset latency, wake after sleep onset, number of awakenings after sleep onset and sleep efficiency for inpatients with AML receiving induction chemotherapy...
April 11, 2018: BMJ Supportive & Palliative Care
Kristine A Wilckens, Fabio Ferrarelli, Matthew P Walker, Daniel J Buysse
Slow-wave activity (SWA), and its coupling with other sleep features, reorganizes cortical circuitry, supporting cognition. This raises the question: can cognition be improved through SWA enhancement? SWA enhancement techniques range from behavioral interventions (such as exercise), which have high feasibility but low specificity, to laboratory-based techniques (such as transcranial stimulation), which have high specificity but are less feasible for widespread use. In this review we describe the pathways through which SWA is enhanced...
April 5, 2018: Trends in Neurosciences
Sabri Seyis, Adnan Kazım Usalan, Ibrahim Rencuzogullari, Özge Kurmuş, Adil Can Gungen
Background: We aimed to investigate the effects of continuous positive airway pressure (CPAP) treatment on electrocardiography (ECG), premature ventricular contraction load on 24-hour Holter recordings, and implantable cardioverter defibrillator (ICD) shocks in patients with obstructive sleep apnea syndrome (OSAS) and heart failure. Methods: Patients with heart failure and ICD and patients with newly diagnosed OSAS were divided into two groups according to CPAP treatment...
2018: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
Yi-Min Yu, Ke-Run Gao, Hao Yu, Yi-Feng Shen, Hua-Fang Li
PURPOSE: The purpose of this study is to investigate the efficacy, safety, and tolerability of agomelatine and paroxetine in Chinese Han patients with major depressive disorder (MDD). METHODS: A 8-week, double-blind, randomized, parallel study was conducted in 14 medical centers in mainland China from December 2011 to September 2012. A total of 264 subjects with a primary Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition diagnosis of MDD were randomly assigned to receive agomelatine 25-50 mg/d (n = 132) or paroxetine 20-40 mg/d (n = 132)...
April 3, 2018: Journal of Clinical Psychopharmacology
Seungyong Han, Jeonghyun Kim, Sang Min Won, Yinji Ma, Daeshik Kang, Zhaoqian Xie, Kyu-Tae Lee, Ha Uk Chung, Anthony Banks, Seunghwan Min, Seung Yun Heo, Charles R Davies, Jung Woo Lee, Chi-Hwan Lee, Bong Hoon Kim, Kan Li, Yadong Zhou, Chen Wei, Xue Feng, Yonggang Huang, John A Rogers
Thin, soft, skin-like sensors capable of precise, continuous measurements of physiological health have broad potential relevance to clinical health care. Use of sensors distributed over a wide area for full-body, spatiotemporal mapping of physiological processes would be a considerable advance for this field. We introduce materials, device designs, wireless power delivery and communication strategies, and overall system architectures for skin-like, battery-free sensors of temperature and pressure that can be used across the entire body...
April 4, 2018: Science Translational Medicine
Marion Cadart, Livio De Sanctis, Sonia Khirani, Alessandro Amaddeo, Lisa Ouss, Brigitte Fauroux
AIM: We evaluated the impact that having a child with sleep-disordered breathing had on their parents, including their own sleep quality. METHODS: Questionnaires were completed by 96 parents of 86 children referred for a sleep study or control of continuous positive airway pressure (CPAP) or noninvasive ventilation (NIV) at the sleep laboratory of the Necker Hospital, Paris, France, between October 2015 and January 2016. The questionnaires evaluated anxiety and depression, family functioning, the parents' quality of life, daytime sleepiness and sleep quality RESULTS: The children had a mean age of seven ±5 years and most of the responses (79%) came from their mothers...
April 4, 2018: Acta Paediatrica
Jeremy E Orr, Pamela N DeYoung, Robert L Owens
No abstract text is available yet for this article.
March 30, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
Mirna Ayache, Kingman P Strohl
STUDY OBJECTIVES: To assess the interrater reliability and accuracy of overnight pulse oximetry (OPO) interpretations by pulmonary fellows using a comprehensive structured template and after a brief educational session. METHODS: Using the template, four pulmonary and critical care (PCC) fellows interpreted OPO saturation waveforms and parameters extracted from 50 adult consecutive in-laboratory sleep studies. The template included three saturation parameters (mean saturation, oxygen desaturation index [ODI], and cumulative desaturation time) and description of the saturation waveform...
March 30, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
Kyungmin Kim, Gun Woo Kang, Jungmin Woo
BACKGROUND: The quality of life (QoL) of patients with end-stage renal disease (ESRD) is very poor, plausibly due to both psychosocial and medical factors. This study aimed to determine the relationship among psychosocial factors, medical factors, and QoL in patients with ESRD undergoing hemodialysis (HD). METHODS: In total, 55 male and 47 female patients were evaluated (mean age, 57.1 ± 12.0 years). The QoL was evaluated using the Korean version of World Health Organization Quality of Life Scale-Abbreviated Version...
April 2, 2018: Journal of Korean Medical Science
Pontus Thorsson, Kerstin Persson Waye, Michael Smith, Mikael Ögren, Eja Pedersen, Jens Forssén
To increase the understanding of wind turbine noise on sleep, human physiological reactions need to be studied in a controlled laboratory setting. The paper presents an outdoor-indoor noise level difference as a function of frequency, applicable to creating wind turbine indoor sounds with the outdoor sounds as input. For this, a combination of measurement data and modeling results has been used. The suggested data are provided in a table.
March 2018: Journal of the Acoustical Society of America
Amiya Patanaik, Ju Lynn Ong, Joshua J Gooley, Sonia Ancoli-Israel, Michael W L Chee
Sleep staging is a fundamental but time consuming process in any sleep laboratory. To greatly speed up sleep staging without compromising accuracy, we developed a novel framework for performing real-time automatic sleep stage classification. The client-server architecture adopted here provides an end-to-end solution for anonymizing and efficiently transporting polysomnography data from the client to the server and for receiving sleep stages in an interoperable fashion. The framework intelligently partitions the sleep staging task between the client and server in a way that multiple low-end clients can work with one server, and can be deployed both locally as well as over the cloud...
March 26, 2018: Sleep
Crystal L Grant, Alison M Coates, Jillian Dorrian, Gemma M Paech, Maja Pajcin, Chris Della Vedova, Kayla Johnson, Gary H Kamimori, Justin Fidock, Eugene Aidman, Siobhan Banks
Caffeine is known for its capacity to mitigate performance decrements. The metabolic side-effects are less well understood. This study examined the impact of cumulative caffeine doses on glucose metabolism, self-reported hunger and mood state during 50 hr of wakefulness. In a double-blind laboratory study, participants were assigned to caffeine (n = 9, 6M, age 21.3 ± 2.1 years; body mass index 21.9 ± 1.6 kg/m2 ) or placebo conditions (n = 8, 4M, age 23.0 ± 2.8 years; body mass index 21.8 ± 1...
March 27, 2018: Journal of Sleep Research
Hyejin Kim, Gyeonghui Jeong, Yoo Kyoung Park, Seung Wan Kang
Background: Sleep disorders can negatively affect quality of life with reduced cognitive function. Since stress and eating behavior are considered crucial factors for sleep, this study's aim was to compare objective quality of sleep and nutrition between subjects with sleep issues and different stress levels. Methods: The investigation was performed in adults (≥18 years old) in the Sleep Laboratory between September 2015 and February 2016. Several measurement instruments were utilized, including the Pittsburgh Sleep Quality Index (PSQI), the Korean version of the Brief Encounter Psychosocial Instrument (BEPSI-K), polysomnography, and a food frequency questionnaire (FFQ)...
January 2018: Journal of Lifestyle Medicine
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