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https://www.readbyqxmd.com/read/29453636/assessment-of-oximetry-based-statistical-classifiers-as-simplified-screening-tools-in-the-management-of-childhood-obstructive-sleep-apnea
#1
Andrea Crespo, Daniel Álvarez, Leila Kheirandish-Gozal, Gonzalo C Gutiérrez-Tobal, Ana Cerezo-Hernández, David Gozal, Roberto Hornero, Félix Del Campo
PURPOSE: A variety of statistical models based on overnight oximetry has been proposed to simplify the detection of children with suspected obstructive sleep apnea syndrome (OSAS). Despite the usefulness reported, additional thorough comparative analyses are required. This study was aimed at assessing common binary classification models from oximetry for the detection of childhood OSAS. METHODS: Overnight oximetry recordings from 176 children referred for clinical suspicion of OSAS were acquired during in-lab polysomnography...
February 16, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29449609/kinesthetic-stimulation-for-obstructive-sleep-apnea-syndrome-an-on-off-proof-of-concept-trial
#2
Alfredo I Hernández, Diego Pérez, Delphine Feuerstein, Corinne Loiodice, Laurence Graindorge, Gustavo Guerrero, Nadège Limousin, Frédéric Gagnadoux, Yves Dauvilliers, Renaud Tamisier, Arnaud Prigent, Philippe Mabo, Amel Amblard, Lotfi Senhadji, Jean-Louis Pépin
Obstructive sleep apnea (OSA) occurs when the upper airway narrows or collapses due to the loss of upper airway muscle activation at sleep onset. This study investigated the effectiveness of triggered kinesthetic stimulation in patients with OSA. This proof-of-concept, open-label, multicenter prospective study was conducted on 24 patients with severe OSA. During a one night evaluation, kinesthetic stimulation was intermittently delivered in 30 minute periods. The duration of apneas and hypopneas during Stim on and Stim off periods were compared...
February 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29447889/correlations-between-pediatric-obstructive-sleep-apnea-and-longitudinal-growth
#3
Do-Yang Park, Ji Ho Choi, So Young Kang, Jinjoo Han, Hun Yi Park, Jin Soon Hwang, Jae Ho Cho, Min Hyuk Cho, Hyun Jun Kim
OBJECTIVES: Pediatric obstructive sleep apnea has a relatively high prevalence and has various negative health and behavioral consequences. Among the various complications of pediatric obstructive sleep apnea, growth disturbance is still controversial. METHOD: 745 pediatric subjects with obstructive sleep apnea diagnosed by in-lab polysomnography were enrolled, after excluding ineligible subjects with abnormal growth related factors. Height, weight, and BMI of enrolled patients were measured and statistically converted to z-scores, and the converted data were analyzed statistically with the polysomnographic results...
March 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29445538/peri-operative-treatment-of-sleep-disordered-breathing-and-outcomes-in-bariatric-patients
#4
Jacques-Henri Meurgey, Richard Brown, Asia Woroszyl-Chrusciel, Joerg Steier
Background: Obstructive sleep apnoea (OSA) is increasingly common in bariatric patients undergoing sedation during elective surgery. However, it has not been established how significant a contributor it is to peri-operative respiratory complications and mortality. We sought to pre-operatively identify OSA in bariatric patients and record peri-operative complications during and after bariatric surgery. Methods: Data were collected and analysed from June 2014 to March 2017 for 410 bariatric surgery patients referred to the sleep laboratory for pre-operative screening and treatment of OSA...
January 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29432885/repetitive-brain-injury-of-juvenile-mice-impairs-environmental-enrichment-induced-modulation-of-rem-sleep-in-adulthood
#5
Jeremy C Borniger, Kyra Ungerleider, Ning Zhang, Kate Karelina, Ulysses J Magalang, Zachary M Weil
Traumatic brain injuries (TBI) are a common and costly ongoing public health concern. Injuries that occur during childhood development can have particularly profound and long-lasting effects. One common consequence and potential mediator of negative outcomes of TBI is sleep disruption which occurs in a substantial proportion of TBI patients. These individuals report greater incidences of insomnia and sleep fragmentation combined with a greater overall sleep requirement meaning that many patients are chronically sleep-deprived...
February 9, 2018: Neuroscience
https://www.readbyqxmd.com/read/29432570/insomnia-perchance-a-dream-results-from-a-nrem-rem-sleep-awakening-study-in-good-sleepers-and-patients-with-insomnia
#6
Bernd Feige, Svetoslava Nanovska, Chiara Baglioni, Benedict Bier, Laura Cabrera, Sarah Diemers, Maximilian Quellmalz, Markus Siegel, Ireni Xeni, Andras Szentkiralyi, John-Peter Doerr, Dieter Riemann
Study Objectives: Insomnia disorder (ID) is a frequent sleep disorder coupled with increased risks for somatic and mental illness. While subjective complaints are severe, polysomnography (PSG) parameters show only modest differences between groups. REM sleep as the most aroused sleep state may be especially vulnerable to be perceived as wake. To directly assess possible differences, we determined auditory waking thresholds and sleep perception in ID patients and healthy control subjects (GSC) in N2 and REM sleep...
February 8, 2018: Sleep
https://www.readbyqxmd.com/read/29425574/sleep-in-ambulatory-patients-with-stable-cirrhosis-of-the-liver
#7
Khaled Saleh, Shahrokh Javaheri
BACKGROUND: Questionnaires indicate that patients with liver disease have disturbed sleep. However, polysomnographic studies to quantify sleep architecture and sleep disorders in this population are lacking. The current study compared polysomnographic findings of two groups of patients with clinically stable but severe end-stage pathology of the liver and heart. METHODS: This was a prospective study of consecutive patients with end-stage liver disease or severe heart failure (HF)...
January 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29411691/prospective-memory-in-idiopathic-rem-sleep-behavior-disorder-with-or-without-mild-cognitive-impairment-a-preliminary-study
#8
Sonia Marcone, Jean-François Gagnon, Catherine Desjardins, Annie-Claude David, Ronald B Postuma, Jacques Montplaisir, Sven Joubert, Isabelle Rouleau
OBJECTIVE: The ability to execute delayed intentions, known as prospective memory (PM), is crucial to everyday living. PM failures are reported in mild cognitive impairment (MCI) and Parkinson's disease, however, no study to date has investigated PM functioning in individuals at high risk of developing these conditions, precisely those diagnosed with idiopathic REM sleep behavior disorder (iRBD). We aimed to assess PM in iRBD according to patients' cognitive status and to determine the underlying nature of their difficulties...
February 7, 2018: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/29411336/central-sleep-apnea-with-cheyne-stokes-breathing-in-heart-failure-from-research-to-clinical-practice-and-beyond
#9
K Terziyski, A Draganova
Characterized by periodic crescendo-decrescendo pattern of breathing alternating with central apneas, Central sleep apnea (CSA) with Cheyne-Stokes Breathing represents a highly prevalent, yet underdiagnosed comorbidity in chronic heart failure (CHF). A diverse body of evidence demonstrates increased morbidity and mortality in the presence of CSB. CSB has been described in both CHF patients with preserved and reduced ejection fraction, regardless of drug treatment. Risk factors for CSB are older age, male gender, high BMI, atrial fibrillation and hypocapnia...
February 7, 2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29411238/hospital-level-care-at-home-for-acutely-ill-adults-a-pilot-randomized-controlled-trial
#10
David M Levine, Kei Ouchi, Bonnie Blanchfield, Keren Diamond, Adam Licurse, Charles T Pu, Jeffrey L Schnipper
BACKGROUND: Hospitals are standard of care for acute illness, but hospitals can be unsafe, uncomfortable, and expensive. Providing substitutive hospital-level care in a patient's home potentially reduces cost while maintaining or improving quality, safety, and patient experience, although evidence from randomized controlled trials in the US is lacking. OBJECTIVE: Determine if home hospital care reduces cost while maintaining quality, safety, and patient experience...
February 6, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29410741/validation-of-midsagittal-jaw-movements-to-measure-sleep-in-healthy-adults-by-comparison-with-actigraphy-and-polysomnography
#11
Bassam Chakar, Frédéric Senny, Anne-Lise Poirrier, Laurent Cambron, Julien Fanielle, Robert Poirrier
OBJECTIVE: In a device based on midsagittal jaw movements analysis, we assessed a sleep-wake automatic detector as an objective method to measure sleep in healthy adults by comparison with wrist actigraphy against polysomnography (PSG). METHODS: Simultaneous and synchronized in-lab PSG, wrist actigraphy and jaw movements were carried out in 38 healthy participants. Epoch by epoch analysis was realized to assess the ability to sleep-wake distinction. Sleep parameters as measured by the three devices were compared...
July 2017: Sleep Science
https://www.readbyqxmd.com/read/29402400/how-much-is-left-in-your-sleep-tank-proof-of-concept-for-a-simple-model-for-sleep-history-feedback
#12
Jillian Dorrian, Steven Hursh, Lauren Waggoner, Crystal Grant, Maja Pajcin, Charlotte Gupta, Alison Coates, David Kennaway, Gary Wittert, Leonie Heilbronn, Chris Della Vedova, Siobhan Banks
Technology-supported methods for sleep recording are becoming increasingly affordable. Sleep history feedback may help with fatigue-related decision making - Should I drive? Am I fit for work? This study examines a "sleep tank" model (SleepTank™), which is analogous to the fuel tank in a car, refilled by sleep, and depleted during wake. Required inputs are sleep period time and sleep efficiency (provided by many consumer-grade actigraphs). Outputs include suggested hours remaining to "get sleep" and percentage remaining in tank (Tank%)...
February 2, 2018: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29398582/revisiting-the-alerting-effect-of-light-a-systematic-review
#13
REVIEW
Qunyan Xu, Cathryne P Lang
Light plays an essential role in maintaining alertness levels. Like other non-image-forming responses, the alerting effect of light is influenced by its spectral wavelength, duration and intensity. Alertness levels are also dependent on circadian rhythm (process C) and homeostatic sleep pressure (process S), consistent with the classic two-process model of sleep regulation. Over the last decade, there has been increasing recognition of an additional process (referred to as the third process) in sleep regulation...
December 7, 2017: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/29392572/the-influence-of-gender-on-symptoms-associated-with-obstructive-sleep-apnea
#14
Carlos Alberto Nigro, Eduardo Dibur, Eduardo Borsini, Silvana Malnis, Glenda Ernst, Ignacio Bledel, Sergio González, Anabella Arce, Facundo Nogueira
BACKGROUND: It has been reported that the clinical expression of obstructive sleep apnea (OSA) may differ in women and men. OBJECTIVE: The objective of this study was to evaluate the influence of gender on reported OSA-related symptoms in a large clinical population of patients. METHODS: The database from the sleep laboratory of a tertiary care center was examined. Adult patients who had undergone a diagnostic polysomnography and completed the Berlin questionnaire, a sleep questionnaire, and the Epworth sleepiness scale were selected...
February 1, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29387256/the-effects-of-diurnal-intermittent-fasting-on-the-wake-promoting-neurotransmitter-orexin-a
#15
Aljohara S Almeneessier, Mohammed Alzoghaibi, Abdulrahman A BaHammam, Mahmoud G Ibrahim, Awad H Olaish, Samar Z Nashwan, Ahmed S BaHammam
BACKGROUND: Food restriction has been demonstrated to increase the alertness in different species and to increase the levels of the wake-promoting neurotransmitter orexin. We hypothesized that diurnal intermittent fasting (DIF) increases orexin-A levels during fasting. Therefore, we conducted this study to assess the effects of DIF, during the month of Ramadan, on orexin, while controlling for lifestyle changes that may accompany Ramadan such as sleep duration, bedtime and wake time, energy expenditure, light exposure, and food...
January 2018: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29381658/cardiovascular-stress-reactivity-and-carotid-intima-media-thickness-the-buffering-role-of-slow-wave-sleep
#16
Ryan C Brindle, Katherine A Duggan, Matthew R Cribbet, Christopher E Kline, Robert T Krafty, Julian F Thayer, Suresh R Mulukutla, Martica H Hall
OBJECTIVE: Exaggerated cardiovascular reactivity to acute psychological stress has been associated with increased carotid intima-media thickness (IMT). However, inter-study variability in this relationship suggests the presence of moderating factors. The current study aimed to test the hypothesis that poor nocturnal sleep, defined as short total sleep time or low slow-wave sleep (SWS), would moderate the relationship between cardiovascular reactivity and IMT. METHODS: Participants (N=99, 65...
January 29, 2018: Psychosomatic Medicine
https://www.readbyqxmd.com/read/29377925/individual-differences-in-compliance-and-agreement-for-sleep-logs-and-wrist-actigraphy-a-longitudinal-study-of-naturalistic-sleep-in-healthy-adults
#17
Steven M Thurman, Nick Wasylyshyn, Heather Roy, Gregory Lieberman, Javier O Garcia, Alex Asturias, Gold N Okafor, James C Elliott, Barry Giesbrecht, Scott T Grafton, Sara C Mednick, Jean M Vettel
There is extensive laboratory research studying the effects of acute sleep deprivation on biological and cognitive functions, yet much less is known about naturalistic patterns of sleep loss and the potential impact on daily or weekly functioning of an individual. Longitudinal studies are needed to advance our understanding of relationships between naturalistic sleep and fluctuations in human health and performance, but it is first necessary to understand the efficacy of current tools for long-term sleep monitoring...
2018: PloS One
https://www.readbyqxmd.com/read/29366374/poststroke-depressive-symptoms-are-associated-with-increased-oxidative-deoxyribonucleic-acid-damage
#18
Chung-Yao Chen, Chia-Ling Chen, Yao-Hung Yang, Chien-Hui Ho, Wen-Chun Tseng
Poststroke depression is independently associated with poor health outcomes, such as increased mortality, disability, anxiety, and lower quality of life. Identifying the potential biomarkers and detailed mechanisms of poststroke depression may improve the effectiveness of therapeutic intervention. In this cross-sectional study, the authors recruited patients with subacute ischemic stroke who were consecutively admitted for neurorehabilitation. Depression was assessed with the Patient Health Questionnaire-9 (PHQ-9), with a cutoff based on a summed-items score of 10...
January 25, 2018: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/29356591/gender-specific-differences-in-access-to-polysomnography-and-prevalence-of-sleep-disorders
#19
Michael Auer, Birgit Frauscher, Margarethe Hochleitner, Birgit Högl
BACKGROUND: Previous studies have shown that women have less access or longer waiting times to high-tech medicine compared with men. This study aimed to detect possible gender differences in access to the diagnostic high-tech method of polysomnography (PSG). Furthermore, the study explored gender differences in prevalence of specific sleep diseases. MATERIALS AND METHODS: Source data of n = 1000 patients, who underwent PSG at the Medical University of Innsbruck, were reviewed...
January 22, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29353391/detection-of-sleep-disordered-breathing-with-ambulatory-holter-monitoring
#20
Ian Grasso, Mark Haigney, David Mortara, Jacob F Collen, Jordanna Hostler, Aimee Moores, Karen Sheikh, William Kelly
PURPOSE: Obstructive sleep apnea (OSA) syndrome is a common condition that can impact clinical outcomes among patients with cardiovascular disease. Screening all subjects with heart disease via polysomnography (PSG) is costly and resource-limited. We sought to compare a Holter monitor-based algorithm to detect OSA to in-laboratory polysomnography (PSG). METHODS: Prospective cohort study of patients undergoing in-laboratory attended PSG for the evaluation of OSA...
January 20, 2018: Sleep & Breathing, Schlaf & Atmung
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