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Sarcopenia

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https://www.readbyqxmd.com/read/29667295/2017-annual-meeting-of-the-australian-and-new-zealand-society-for-sarcopenia-and-frailty-research-anzssfr-24-25-november-2017-university-of-adelaide-south-australia
#1
(no author information available yet)
No abstract text is available yet for this article.
April 2018: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/29665258/health-related-quality-of-life-and-fall-risk-associated-with-age-related-body-composition-changes-sarcopenia-obesity-and-sarcopenic-obesity
#2
Zeynel Abidin Öztürk, İbrahim Halil Türkbeyler, Azer Abiyev, Seval Kul, Bahadır Edizer, Funda Datli Yakaryılmaz, Gülçimen Soylu
BACKGROUND: Sarcopenia, obesity, and sarcopenic obesity are various features of the aging process that can cause important health issues. The present study was undertaken to investigate the interrelationship between those body composition changes including their clinical components and the quality of life variables. METHODS: 423 individuals aged 65 years or more were included in this cross-sectional study. Sarcopenia was diagnosed according to The European Working Group on Sarcopenia in Older People criteria...
April 17, 2018: Internal Medicine Journal
https://www.readbyqxmd.com/read/29663263/concise-commentary-visceral-obesity-sarcopenia-and-cancer-surgery-increasing-fitness-decreases-risk
#3
EDITORIAL
Oliver A Varban
No abstract text is available yet for this article.
April 16, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29662881/the-continuum-of-aging-and-age-related-diseases-common-mechanisms-but-different-rates
#4
REVIEW
Claudio Franceschi, Paolo Garagnani, Cristina Morsiani, Maria Conte, Aurelia Santoro, Andrea Grignolio, Daniela Monti, Miriam Capri, Stefano Salvioli
Geroscience, the new interdisciplinary field that aims to understand the relationship between aging and chronic age-related diseases (ARDs) and geriatric syndromes (GSs), is based on epidemiological evidence and experimental data that aging is the major risk factor for such pathologies and assumes that aging and ARDs/GSs share a common set of basic biological mechanisms. A consequence is that the primary target of medicine is to combat aging instead of any single ARD/GSs one by one, as favored by the fragmentation into hundreds of specialties and sub-specialties...
2018: Frontiers in Medicine
https://www.readbyqxmd.com/read/29662836/association-between-loss-of-skeletal-muscle-mass-and-mortality-and-tumor-recurrence-in-hepatocellular-carcinoma-a-systematic-review-and-meta-analysis
#5
REVIEW
Ke-Vin Chang, Jin-De Chen, Wei-Ting Wu, Kuo-Chin Huang, Chia-Tzu Hsu, Der-Sheng Han
Background: Hepatocellular carcinoma (HCC) has multiple prognostic factors, and there is an increase in knowledge about the body composition and physical status of patients with HCC. The present meta-analysis aimed to explore whether loss of skeletal muscle mass is associated with mortality and tumor recurrence in patients with HCC. Method: A systematic search was conducted for published literature using PubMed, Embase, and Scopus. We included cohort or case-control studies investigating patients with HCC...
March 2018: Liver Cancer
https://www.readbyqxmd.com/read/29662835/preoperative-low-muscle-mass-and-low-muscle-quality-negatively-impact-on-pulmonary-function-in-patients-undergoing-hepatectomy-for-hepatocellular-carcinoma
#6
Hisaya Shirai, Toshimi Kaido, Yuhei Hamaguchi, Atsushi Kobayashi, Shinya Okumura, Siyuan Yao, Shintaro Yagi, Naoko Kamo, Kojiro Taura, Hideaki Okajima, Shinji Uemoto
Background: Sarcopenia is a prognostic factor for mortality in digestive surgery. However, the correlation between preoperative cardiopulmonary function and sarcopenia in patients undergoing hepatectomy for hepatocellular carcinoma (HCC) remains unclear. Methods: The present study investigated the impact of preoperative sarcopenia on cardiopulmonary function in 402 patients who underwent first hepatectomy for HCC between April 2005 and April 2015. The quantity and quality of skeletal muscle were evaluated using psoas muscle index (PMI) and intramuscular adipose tissue content (IMAC), respectively, as determined from preoperative computed tomography imaging...
March 2018: Liver Cancer
https://www.readbyqxmd.com/read/29660782/sglt2-inhibitor-induced-changes-in-body-composition-and-simultaneous-changes-in-metabolic-profile-52-week-prospective-light-study-with-luseogliflozin
#7
Takashi Sasaki, Masahiro Sugawara, Masahiro Fukuda
AIMS: It is unclear how changes in body composition induced by sodium-glucose cotransporter 2 (SGLT2) inhibitor treatment correlate with metabolic profile changes. We aimed to clarify how metabolic profile changes correlate with body component changes, and if SGLT2 inhibitor treatment causes sarcopenia and bone mineral content (BMC) loss. MATERIALS AND METHODS: Moderately obese Japanese type 2 diabetes (T2D) patients, treated with luseogliflozin for a year, were observed prospectively and evaluated for body composition changes...
April 16, 2018: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/29659725/bone-morphogenetic-proteins-bmps-satellite-cells-and-sarcopenia-perspective-in-translational-medicine
#8
Umberto Tarantino, Manuel Scimeca
No abstract text is available yet for this article.
April 12, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29658780/inter-and-intraobserver-variability-of-an-anatomical-landmark-based-manual-segmentation-method-by-mri-for-the-assessment-of-skeletal-muscle-fat-content-and-area-in-subjects-from-the-general-population
#9
Lena Sophie Kiefer, Jana Fabian, Roberto Lorbeer, Jürgen Machann, Corinna Storz, Mareen Sarah Kraus, Elke Wintermeyer, Christopher L Schlett, Frank Roemer, Konstantin Nikolaou, Annette Peters, Fabian Bamberg
OBJECTIVES: Changes in skeletal muscle composition, such as fat content and mass, may exert unique metabolic and musculoskeletal risks; however, the reproducibility of their assessment is unknown. We determined the variability of the assessment of skeletal muscle fat content and area by magnetic resonance imaging (MRI) in a population-based sample. METHODS: A random sample from a prospective, community-based cohort study (KORA-FF4) was included. Skeletal muscle fat content was quantified as proton-density fat-fraction (PDFF) and area as cross-sectional area (CSA) in multi-echo Dixon sequences (TR 8...
April 16, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29656887/sarcopenia-and-adiposity-linked-to-overall-survival
#10
Elizabeth Gourd
No abstract text is available yet for this article.
April 12, 2018: Lancet Oncology
https://www.readbyqxmd.com/read/29656012/muscle-strength-and-size-are-associated-with-motor-unit-connectivity-in-aged-mice
#11
Kajri A Sheth, Chitra C Iyer, Christopher G Wier, Alexander E Crum, Anna Bratasz, Stephen J Kolb, Brian C Clark, Arthur H M Burghes, W David Arnold
In older adults, the loss of muscle strength (dynapenia) and the loss of muscle mass (sarcopenia) are important contributors to the loss of physical function. We sought to investigate dynapenia, sarcopenia, and the loss of motor unit function in aging mice. C57BL/6J mice were analyzed with cross-sectional (males: 3 vs. 27 months; males and females: 8 vs. 12 vs. 20 months) and longitudinal studies (males: 10-25 months) using in vivo electrophysiological measures of motor unit connectivity (triceps surae compound muscle action potential and motor unit number estimation), in vivo measures of plantar flexion torque, magnetic resonance imaging of hind limb muscle volume, and grip strength...
March 23, 2018: Neurobiology of Aging
https://www.readbyqxmd.com/read/29655775/relationship-between-water-intake-and-skeletal-muscle-mass-in-elderly-koreans-a-nationwide-population-based-study
#12
Jun-Il Yoo, Hana Choi M D, Sang-Yoon Song, Ki-Soo Park, Dong-Hoon Lee, Yong-Chan Ha
OBJECTIVES: The purposes of this study were to evaluate the correlation between sarcopenia and water intake and investigate lack of daily water intake in the presence of sarcopenia in an elderly population. METHODS: Data from 3656 participants (1582 men and 2074 women) were analyzed using the Korea National Health and Nutrition Examination Survey. Sarcopenia was defined in accordance with the criteria of the Asia Working Group for Sarcopenia. Water intake was assessed using the dietary water adequacy ratio and was calculated by dividing the daily water intake from fluid by the recommended daily amount of 1000 mL in men and 900 mL in women...
February 12, 2018: Nutrition
https://www.readbyqxmd.com/read/29650344/non-invasive-testing-for-sarcopenia-predicts-future-cardiovascular-events-in-patients-with-chronic-kidney-disease
#13
Shinsuke Hanatani, Yasuhiro Izumiya, Yoshiro Onoue, Tomoko Tanaka, Masahiro Yamamoto, Toshifumi Ishida, Satoru Yamamura, Yuichi Kimura, Satoshi Araki, Yuichiro Arima, Taishi Nakamura, Koichiro Fujisue, Seiji Takashio, Daisuke Sueta, Kenji Sakamoto, Eiichiro Yamamoto, Sunao Kojima, Koichi Kaikita, Kenichi Tsujita
BACKGROUND: Sarcopenia is frequently observed and associated with poor outcomes in patients with chronic kidney disease (CKD). A simple screening test for sarcopenia using age, grip strength, and calf circumference was recently developed. However, the clinical utility of this sarcopenia score in patients with CKD remains unclear. METHODS AND RESULTS: We calculated the sarcopenia score of 265 patients with CKD and followed the patients for cardiovascular events. The endpoint of this study was the composite of cardiovascular hospitalization and total mortality...
April 5, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29649572/associations-of-sarcopenic-obesity-with-the-metabolic-syndrome-and-insulin-resistance-over-five-years-in-older-men-the-concord-health-and-ageing-in-men-project
#14
David Scott, Robert Cumming, Vasi Naganathan, Fiona Blyth, David G Le Couteur, David J Handelsman, Markus Seibel, Louise M Waite, Vasant Hirani
PURPOSE: Previous cross-sectional studies investigating associations of sarcopenic obesity with metabolic syndrome (MetS) and insulin resistance have not utilised consensus definitions of sarcopenia. We aimed to determine associations of sarcopenic obesity with MetS and insulin resistance over five years in community-dwelling older men. METHODS: 1231 men aged ≥70 years had appendicular lean mass (ALM) and body fat percentage assessed by dual-energy X-ray absorptiometry and hand grip strength and gait speed tests...
April 9, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29642478/diagnostic-criteria-and-clinical-outcomes-in-sarcopenia-research-a-literature-review
#15
REVIEW
Alex Han, Steven L Bokshan, Stephen E Marcaccio, J Mason DePasse, Alan H Daniels
By the sixth decade of life, nearly one quarter of the population has substantial muscle atrophy, or sarcopenia. Despite the creation of a standardized definition of sarcopenia by the European Working Group on Sarcopenia in Older People, variability may exist in the diagnostic criteria utilized for clinical sarcopenia research. The primary objectives of this review were to characterize diagnostic criteria used for measurement of sarcopenia in original studies, and to describe associations between sarcopenia and important clinical outcomes...
April 8, 2018: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/29624982/clinical-interventions-in-osteosarcopenic-obesity-nutrition-physical-and-psychological-activity
#16
Ana Isabel García-González, Zoraida Axtle-Serrano, Miriam López-Teros, Claudia Szlejf, Adrián Martínez-Ruiz, Oscar Rosas-Carrasco
Osteosarcopenic obesity (OSO) is a condition associated with adverse outcomes in older adults. Since it is a condition which includes three tissues (obesity, sarcopenia and osteopenia/osteoporosis), it requires simultaneous and multidisciplinary clinical interventions to revert it. Until this moment, there have been published review articles only focused on nutrition or physical activity. However, we believe that assembling the existing evidence on potential treatments (nutritional intervention with micro- and macronutrients), physical activity, farmacological treatment for osteopenia/osteoporosis, possible farmacological treatment for sarcopenia, and, finally, psychological interventions focused on the treatment of psychiatric comorbidities (such as anxiety or depression) will help healthcare providers to improve the body composition of older adults...
2018: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/29624960/associated-factors-with-sarcopenia-among-mexican-elderly-2012-national-health-and-nutrition-survey
#17
(no author information available yet)
Background: Sarcopenia involves the loss of skeletal muscle mass and age-related functionality; it diminishes physical independence, health and quality of life. In 2016 it was added to the International Classification of Diseases (ICD-10). Information about the frequency of sarcopenia among Mexican older adults is scarce. The objective was to analyze associated factors with sarcopenia in Mexican older adults through the 2012 National Health and Nutrition Survey data. Methods: Cross-sectional study which included subjects of 60 years of age or more with simultaneous information on health and anthropometry questionnaires from the 2012 National Health and Nutrition Survey...
2018: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/29624617/reference-values-for-hand-grip-strength-in-the-south-korean-population
#18
Chung Reen Kim, Young-Jee Jeon, Moon Chan Kim, Taeheum Jeong, Woo Ram Koo
OBJECTIVE: To establish reference values for hand grip strength (HGS) in a healthy Korean population and to identify the dependent anthropometric variables that affect HGS. METHODS: Based on the sixth Korea National Health and Nutrition Examination Survey from 2014 to 2015, we analyzed the HGS data of 7,969 South Koreans. Individuals with specific chronic diseases and who reported poor subjective health status were excluded to ensure a healthy population sample...
2018: PloS One
https://www.readbyqxmd.com/read/29624343/oxidative-stress-in-the-elderly-with-diabetes-mellitus-or-hypertension
#19
Aleida Rodríguez-Castañeda, Katia Leticia Martínez-González, Rosalinda Sánchez-Arenas, Sergio Sánchez-García, Israel Grijalva, Lourdes Basurto-Acevedo, Juan Cuadros-Moreno, Eliseo Ramírez-García, Paola García-de la Torre
Background: Mexico City has the highest aging rate in the country, as well as a high prevalence of diabetes mellitus (DM) and hypertension (HT). It is known that each one of these conditions increase oxidative stress (OS) independently. Methods: With this study we described changes in OS of 18 patients without DM or HT (controls), 12 with DM, 23 with HT, and 18 with DM and HT, all of them members of the COSFAMM (Cohorte de Obesidad, Sarcopenia y Fragilidad en Adultos Mayores de México)...
2018: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/29623651/is-iron-accumulation-a-possible-risk-factor-for-sarcopenia
#20
Guoyang Zhao
Sarcopenia has a high incidence among the elderly, with significant negative effects on the quality of life. The pathogenesis of sarcopenia is complex, and many factors are involved in its development and progression. Sarcopenia might be associated with iron accumulation given that (1) age-related iron accumulation was found in the skeletal muscle, (2) excess iron could cause skeletal muscle damage or atrophy, and (3) patients with sarcopenia showed higher levels of serum ferritin. Understanding the etiology and pathogenesis of sarcopenia would help to develop new treatment and preventive methods, thereby improving the quality of life of the elderly patients...
April 5, 2018: Biological Trace Element Research
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