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Sarcopenia

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https://www.readbyqxmd.com/read/28731551/sarcopenia-and-hospitalisation-costs-in-older-adults-a-cross-sectional-study
#1
Ana C Antunes, Daniela A Araújo, Manuel T Veríssimo, Teresa F Amaral
AIM: The impact of sarcopenia on hospitalisation has been under intense investigation; however, little is known about the association between sarcopenia and their costs among hospitalised patients. The aim of the present study was to quantify the association between sarcopenia and hospitalisation costs among older adults. METHODS: A cross-sectional study was conducted in 201 hospitalised older adults in a general hospital. Sarcopenia was identified according to the European Working Group on Sarcopenia in Older People (EWGSOP) criteria...
February 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28728198/-nutrition-of-polymorbid-patients-data-or-opinions
#2
Mathias Plauth
Polymorbidity and old age are rather the rule than the exception in hospitalised patients. Malnutrition is common in such patients and should be identified by appropriate screening and assessment measures in order to devise a nutrition plan and act accordingly. Unlike in the UK or The Netherlands, malnutrition screening and nutrition teams are not mandatory for German hospitals. Malnutrition and, in particular, sarcopenia are indicators of a nutrition associated risk or increased morbidity and mortality. Malnutrition can affect patients of any medical discipline and, therefore, is managed most efficiently by the interdisciplinary and multiprofessional nutrition team...
July 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28726081/psoas-muscle-volume-as-a-predictor-of-peripheral-neurotoxicity-induced-by-primary-chemotherapy-in-ovarian-cancers
#3
Tomoyuki Yoshikawa, Masashi Takano, Morikazu Miyamoto, Isao Yajima, Yukihiro Shimizu, Yusuke Aizawa, Yuki Suguchi, Miki Moriiwa, Tadashi Aoyama, Hiroaki Soyama, Tomoko Goto, Junko Hirata, Ayako Suzuki, Hidenori Sasa, Isao Nagaoka, Hitoshi Tsuda, Kenichi Furuya
PURPOSE: Low skeletal muscle mass (sarcopenia) has been reported to have an influence on survival and toxicities of chemotherapy in several solid tumors. The impact of sarcopenia on the treatment of ovarian cancers has not been determined. The present study aimed to evaluate correlation between sarcopenia and toxicities of chemotherapy in ovarian cancers. METHODS: Medical charts of the ovarian cancer patients that received chemotherapy with paclitaxel and carboplatin at our hospital between 2010 and 2015 were retrospectively reviewed...
July 19, 2017: Cancer Chemotherapy and Pharmacology
https://www.readbyqxmd.com/read/28726035/evaluation-of-physical-activity-in-sarcopenic-conditions-of-kidney-transplantation-recipients
#4
Masaaki Yanishi, Hiroyasu Tsukaguchi, Yutaka Kimura, Yuya Koito, Kenji Yoshida, Maiko Seo, Eri Jino, Motohiko Sugi, Hidefumi Kinoshita, Tadashi Matsuda
INTRODUCTION: Sarcopenia is an involuntary decline in skeletal muscle mass, strength, and function that normally proceed with aging but may develop faster under some chronic disease conditions. In this study, we compared the physical activity between sarcopenia and non-sarcopenia subgroups in kidney transplant recipients. METHODS: Fifty-eight recipients (42 males and 16 females) were enrolled in this study. Mean age of the recipients was 46.6 ± 12.7 years. Mean duration of dialysis was 2...
July 19, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28721834/the-interaction-between-nutrition-and-exercise-for-promoting-health-and-performance
#5
Oliver C Witard, Derek Ball
The theme of The Nutrition Society Spring Conference 2017 was on the interaction between nutrition and exercise for promoting healthy ageing, maintaining cognitive function and improving the metabolic health of the population. The importance of this theme is highlighted by the public health issues surrounding obesity, diabetes and the age-related loss of skeletal muscle mass (sarcopenia). The opening symposium provided a historical perspective of both invasive and non-invasive methodologies for measuring exercise energetics and energy balance...
July 19, 2017: Proceedings of the Nutrition Society
https://www.readbyqxmd.com/read/28721555/the-value-of-physical-performance-measurements-alongside-assessment-of-sarcopenia-in-predicting-receipt-and-completion-of-planned-treatment-in-non-small-cell-lung-cancer-an-observational-exploratory-study
#6
Jemima T Collins, Simon Noble, John Chester, Helen E Davies, William D Evans, Daniel Farewell, Jason F Lester, Diane Parry, Rebecca Pettit, Anthony Byrne
INTRODUCTION: The presence of muscle mass depletion is associated with poor outcomes and survival in cancer. Alongside muscle mass, assessment of muscle strength or physical performance is essential for the diagnosis of sarcopenia. Non-small cell lung cancer (NSCLC) is a prevalent form of cancer with high mortality, and Eastern Cooperative Oncology Group (ECOG) Performance Status (PS) is commonly used to assess patients' suitability for treatment. However, a significant proportion of patients with good PS are unable to complete multidisciplinary team (MDT)-planned treatment...
July 18, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28721434/muscle-measures-and-nutritional-status-at-hospital-admission-predict-survival-and-independent-living-of-older-patients-the-empower-study
#7
S Verlaan, J M Van Ancum, V D Pierik, J P Svan Wijngaarden, K Scheerman, C G M Meskers, A B Maier
OBJECTIVES: Older adults with sarcopenia and malnutrition are at risk for co-morbidities, hospitalization, institutionalization, and mortality. In case of hospitalization, risks may be further increased, especially in case of suboptimal dietary intake. The aim of our study was to assess whether muscle mass, muscle strength, functional performance, and nutritional status at hospital admission were associated with survival and independent living among older patients three months after discharge...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/28721028/frailty-in-community-dwelling-older-adults-association-with-adverse-outcomes
#8
Sergio Sánchez-García, Carmen García-Peña, Antoni Salvà, Rosalinda Sánchez-Arenas, Víctor Granados-García, Juan Cuadros-Moreno, Laura Bárbara Velázquez-Olmedo, Ángel Cárdenas-Bahena
BACKGROUND: The study of frailty is important to identify the additional needs of medical long-term care and prevent adverse outcomes in community dwelling older adults. This study aimed to determine the prevalence of frailty and its association with adverse outcomes in community dwelling older adults. METHODS: A cross-sectional study was carried out from April to September 2014. The population sample was 1,252 older adults (≥60 years) who were beneficiaries of the Mexican Institute of Social Security (IMSS) in Mexico City...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28718587/-drugs-induced-osteopathies
#9
Bérengère Aubry-Rozier
Drug induced bone diseases concerns : induced osteoporosis, induced osteomalacia (by loss of calcium, phosphate or vitamin D) and induced sarcopenia. Some of these drugs are well known, such as anti-hormones, corticotherapy (which could induce all of osteoporosis, osteomalacia and sarcopenia). In the present article, we will focus on 3 others less known but frequently used drugs : iron replacement, proton pump inhibitors therapy, and serotonin reuptake inhibitor antidepressants treatment. For each of them we will discuss the pathophysiological mechanism leading to bone fragility as well as the recommendations of prevention / management to be proposed in case of absolute necessity of the treatment...
March 8, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28717813/cut-off-points-for-muscle-mass-not-grip-strength-or-gait-speed-determine-variations-in-sarcopenia-prevalence
#10
F Masanés, X Rojano I Luque, A Salvà, J A Serra-Rexach, I Artaza, F Formiga, F Cuesta, A López Soto, D Ruiz, A J Cruz-Jentoft
OBJECTIVES: The European Working Group on Sarcopenia in Older People (EWGSOP) has proposed different methods and cut-off points for the three parameters that define sarcopenia: muscle mass, muscle strength and physical performance. Although this facilitates clinical practice, it limits comparability between studies and leads to wide differences in published prevalence rates. The aim of this study was to assess how changes in cut-off points for muscle mass, gait speed and grip strength affected sarcopenia prevalence according to EWGSOP criteria...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28712907/skeletal-muscle-as-a-factor-contributing-to-better-stratification-of-older-patients-with-traumatic-brain-injury-a-retrospective-cohort-study
#11
Keita Shibahashi, Kazuhiro Sugiyama, Hidenori Hoda, Yuichi Hamabe
BACKGROUND: Traumatic brain injury (TBI) in older patients is becoming an increasing problem, and methods that help predict outcomes in this population are needed. The objective of this study was to evaluate skeletal muscle mass as a predictive marker for TBI outcome in older patients. METHODS: Older patients (≥60 years) with TBI were included in this study and clinical outcome was assessed using the Glasgow Outcome Scale (GOS) at six months post-injury. Patients were classified according to their GOS score as having good outcome (GOS 3-5) or poor outcome (GOS 1 and 2)...
July 13, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28712265/jaeumganghwa-tang-a-traditional-herbal-formula-improves-muscle-function-and-attenuates-muscle-loss-in-aged-mice
#12
Yun Mi Lee, Ohn Soon Kim
PURPOSE: Jaeumganghwa-Tang (JGT), a traditional herbal formula composed of 12 medicinal herbs, is used for the treatment of age-related diseases. In the present study, we investigated the effects of JGT on muscle mass and function in aged mice. METHODS: Young (5-month-old) and old (19-month-old) male C57BL/6 mice were divided into two groups each; one group received JGT (75 mg/d) and the other group received the vehicle for 6 weeks. At the end of the experimental period, muscle strength was examined using the wire hang test, and the tibialis anterior and gastrocnemius muscles were weighed...
March 31, 2017: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/28711604/an-animal-model-of-co-existing-sarcopenia-and-osteoporotic-fracture-in-senescence-accelerated-mouse-prone-8-samp8
#13
Ning Zhang, Simon Kwoon Ho Chow, Kwok Sui Leung, Ho Hin Lee, Wing Hoi Cheung
Sarcopenia and osteoporotic fracture are common aging-related musculoskeletal problems. Recent evidences report that osteoporotic fracture patients showed high prevalence of sarcopenia; however, current clinical practice basically does not consider sarcopenia in the treatment or rehabilitation of osteoporotic fracture. There is almost no report studying the relationship of the co-existing of sarcopenia and osteoporotic fracture healing. In this study, we validated aged senescence accelerated mouse prone 8 (SAMP8) and senescence accelerated mouse resistant 1 (SAMR1) as animal models of senile osteoporosis with/without sarcopenia...
July 12, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28711425/minerals-and-sarcopenia-the-role-of-calcium-iron-magnesium-phosphorus-potassium-selenium-sodium-and-zinc-on-muscle-mass-muscle-strength-and-physical-performance-in-older-adults-a%C3%A2-systematic-review
#14
REVIEW
Carliene van Dronkelaar, Aafke van Velzen, Maya Abdelrazek, Anouk van der Steen, Peter J M Weijs, Michael Tieland
INTRODUCTION: Minerals may contribute to prevent and treat sarcopenia, the age-related loss of muscle mass, muscle strength, and physical performance. So far, there is no comprehensive review on the impact of minerals on sarcopenia outcomes. The aim of this systematic review is to evaluate the role of calcium, iron, magnesium, phosphorus, potassium, selenium, sodium, and zinc on muscle mass, muscle strength, and physical performance in older adults. METHODS: A systematic search was conducted between March 2016 and July 2016, in the PubMed database using predefined search terms...
July 12, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28709946/frailty-and-sarcopenia-do-not-predict-adverse-events-in-an-elderly-population-undergoing-non-complex-primary-elective-surgery-for-degenerative-conditions-of-the-lumbar-spine
#15
Raphaële Charest-Morin, John Street, Honglin Zhang, Taren Roughead, Tamir Ailon, Michael Boyd, Marcel Dvorak, Brian Kwon, Scott Paquette, Nicolas Dea, Charles G Fisher, Alana M Flexman
BACKGROUND CONTEXT: Sarcopenia measured by normalized total psoas area (NTPA) has been shown to predict mortality and adverse events (AE) in numerous surgical populations. The relationship between sarcopenia and postoperative outcomes after surgery for degenerative spine disease (DSD) has not been investigated. PURPOSE: This study aimed to determine the relationships between sarcopenia, frailty and postoperative adverse events in the elderly DSD population. Secondary objectives were to describe the distribution and predictors of NTPA and to determine the relationship between sarcopenia, frailty and length of stay, discharge to a facility and in-hospital mortality...
July 11, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28705573/the-effects-of-neoadjuvant-axitinib-on-anthropometric-parameters-in-patients-with-locally-advanced-non-metastatic-renal-cell-carcinoma
#16
Lisly Chéry, Leonardo D Borregales, Bryan Fellman, Diana L Urbauer, Naveen Garg, Nathan Parker, Matthew H G Katz, Christopher G Wood, Jose A Karam
OBJECTIVE: To examine the effect that neoadjuvant axitinib for the treatment of localized renal cell carcinoma has on body compartment composition. PATIENTS AND METHODS: The study was based on a single-institution, single-arm clinical trial that enrolled 24 patients with locally advanced non-metastatic biopsy-proven clear cell renal cell carcinoma. Patients received axitinib orally for up to 12 weeks. Computed tomography scans were completed before the start of treatment, after 7 weeks of treatment and at the completion of 12 weeks of treatment...
July 10, 2017: Urology
https://www.readbyqxmd.com/read/28704095/sarcopenia-an-endocrine-disorder
#17
Alexis McKee, John E Morley, Alvin M Matsumoto, Aaron Vinik
Sarcopenia is defined as low muscle function (walking speed or grip strength) in the presence of low muscle mass. A simple screening test - the SARC-F - is available to identify persons with sarcopenia. The major endocrine causes of sarcopenia are diabetes mellitus and male hypogonadism. Other causes are decreased physical activity, loss of motor neuron units, weight loss, inflammatory cytokines, reduced blood flow to muscles, very low 25(OH) vitamin D levels and decreased growth hormone and IGF-1. Treatment for sarcopenia includes resistance and aerobic exercise, leucine enriched essential amino acids, and vitamin D...
July 13, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28702888/cushing-s-syndrome-a-model-for-sarcopenic-obesity
#18
Michael Drey, Christina M Berr, Martin Reincke, Julia Fazel, Jochen Seissler, Jochen Schopohl, Martin Bidlingmaier, Stefanie Zopp, Nicole Reisch, Felix Beuschlein, Andrea Osswald, Ralf Schmidmaier
PURPOSE: Obesity and its metabolic impairments are discussed as major risk factors for sarcopenia leading to sarcopenic obesity. Cushing's syndrome is known to be associated with obesity and muscle atrophy. We compared Cushing's syndrome with matched obese controls regarding body composition, physical performance, and biochemical markers to test the hypothesis that Cushing's syndrome could be a model for sarcopenic obesity. METHODS: By propensity score matching, 47 controls were selected by body mass index and gender as obese controls...
July 12, 2017: Endocrine
https://www.readbyqxmd.com/read/28701179/a-study-on-relationship-between-elderly-sarcopenia-and-inflammatory-factors-il-6-and-tnf-%C3%AE
#19
Ai-Lin Bian, Hui-Ying Hu, Yu-Dong Rong, Jian Wang, Jun-Xiong Wang, Xin-Zi Zhou
BACKGROUND: This report aims to study the relationship between sarcopenia of elderly in community and inflammatory factors IL-6 and TNF-α. METHODS: A total of 441 elders who undertook physical examinations were included into this study. The age of these subjects were >60, in which 235 subjects were male and 206 subjects were female. According to the diagnostic standards of sarcopenia set by EWGSOP and AWGS, these subjects were divided into two groups: sarcopenia, and non-sarcopenia groups...
July 12, 2017: European Journal of Medical Research
https://www.readbyqxmd.com/read/28701132/sarcopenia-a-potential-cause-and-consequence-of-type-2-diabetes-in-australia-s-ageing-population
#20
David Scott, Barbora de Courten, Peter R Ebeling
No abstract text is available yet for this article.
July 17, 2017: Medical Journal of Australia
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