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https://www.readbyqxmd.com/read/29136552/development-and-validation-of-modified-quechers-method-coupled-with-lc-ms-ms-for-simultaneous-determination-of-cymiazole-fipronil-coumaphos-fluvalinate-amitraz-and-its-metabolite-in-various-types-of-honey-and-royal-jelly
#1
Weijia Zheng, Jin-A Park, A M Abd El-Aty, Seong-Kwan Kim, Sang-Hyun Cho, Jeong-Min Choi, Hee Yi, Soo-Min Cho, Amer Ramadan, Ji Hoon Jeong, Jae-Han Shim, Ho-Chul Shin
Over the past few decades, honey products have been polluted by different contaminants, such as pesticides, which are widely applied in agriculture. In this work, a modified EN - quick, easy, cheap, effective, rugged, and safe (QuEChERS) extraction method was developed for the simultaneous quantification of pesticide residues, including cymiazole, fipronil, coumaphos, fluvalinate, amitraz, and its metabolite 2,4-dimethylaniline (2,4-DMA), in four types of honey (acacia, wild, chestnut, and manuka) and royal jelly...
November 8, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29077554/antifungal-properties-of-essential-oils-for-improvement-of-indoor-air-quality-a-review
#2
REVIEW
Harriet Whiley, Sharyn Gaskin, Tiffany Schroder, Kirstin Ross
Concerns regarding indoor air quality, particularly the presence of fungi and moulds, are increasing. The potential for essential oils to reduce, control or remove fungi, is gaining interest as they are seen as a "natural" alternative to synthetic chemical fungicides. This review examines published research on essential oils as a method of fungal control in indoor environments. It was difficult to compare the relative performances of essential oils due to differences in research methods and reporting languages...
October 27, 2017: Reviews on Environmental Health
https://www.readbyqxmd.com/read/29048804/-determination-of-characteristic-compound-in-manuka-honey-by-automatic-on-line-solid-phase-extraction-liquid-chromatography-high-resolution-mass-spectrometry
#3
Chongyu Shen, Siyan Guo, Tao Ding, Yun Liu, Lei Chen, Xiaoqing Fei, Rui Zhang, Bin Wu, Weijian Shen, Lei Chen, Feng Zhang, Feng Feng, Xiaojun Deng, Xionghai Yi, Gongjun Yang, Guoqiang Chen
A method for the determination of characteristic compound 3,5-dimethoxybenzoate-4-diglucoside (leptosperin) in manuka honey was developed by automatic on-line solid phase extraction-liquid chromatography-high resolution mass spectrometry (SPE-LC-HRMS). The samples were separated on a Dikma Diamonsil Plus C18 column (150 mm×4.6 mm, 5 μm) using the mobile phases of 0.1% (v/v) formic acid aqueous solution and acetonitrile with gradient elution. The compound was detected with negative electrospray ionization (ESI(-)) in Target-MS(2) mode...
October 8, 2017: Se Pu, Chinese Journal of Chromatography
https://www.readbyqxmd.com/read/29032921/treatment-of-contact-lens-related-dry-eye-with-antibacterial-honey
#4
Daniel Wong, Julie M Albietz, Huan Tran, Cimonette Du Toit, Anita Hui Li, Tina Yun, Jee Han, Katrina L Schmid
AIM: Contact lens induced dry eye affects approximately 50% of contact lens wearers. The aim was to assess the effects of Manuka (Leptospermum sp.) honey eye drops (Optimel, Melcare, Australia) on dry eye in contact lens wearers. The safety of the honey eye drops in contact lens wear and contact lens wearers' compliance were also evaluated. DESIGN: Prospective, randomised, cross over study, examiner masked, pilot treatment trial. METHODS: Twenty-four participants aged 20 to 55 years with contact lens related dry eye were recruited and randomised to two treatment groups; 20 completed the study...
October 9, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29029151/combined-toxicity-of-three-essential-oils-against-aedes-aegypti-diptera-culicidae-larvae
#5
Ephantus J Muturi, Jose L Ramirez, Kenneth M Doll, Michael J Bowman
Essential oils are potential alternatives to synthetic insecticides because they have low mammalian toxicity, degrade rapidly in the environment, and possess complex mixtures of bioactive constituents with multi-modal activity against the target insect populations. Twenty-one essential oils were initially screened for their toxicity against Aedes aegypti (L.) larvae and three out of the seven most toxic essential oils (Manuka, oregano, and clove bud essential oils) were examined for their chemical composition and combined toxicity against Ae...
November 7, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/28960886/a-preliminary-in-vitro-evaluation-of-the-bioactive-potential-of-cryogel-scaffolds-incorporated-with-manuka-honey-for-the-treatment-of-chronic-bone-infections
#6
Katherine R Hixon, Tracy Lu, Marissa N Carletta, Sarah H McBride-Gagyi, Blythe E Janowiak, Scott A Sell
Previous studies have identified honey as an agent in bacterial inhibition and a mediator in lowering the pH at the wound site. Manuka honey (MH), indigenous to New Zealand, contains a Unique Manuka Factor that provides an additional antibacterial agent. While there are many potential benefits to incorporating MH into wounds, there is currently no ideal way to deliver the material to the site of injury. Cryogels are a type of scaffold that possess high porosity, mechanical stability, and a sponge-like consistency...
September 27, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28958512/physicochemical-and-viscoelastic-properties-of-honey-from-medicinal-plants
#7
Huong Thi Lan Nguyen, Naksit Panyoyai, Vilia Darma Paramita, Nitin Mantri, Stefan Kasapis
The present work investigated the physicochemical and structural properties of Tulsi, Alfalfa and two varieties of Manuka honey derived from medicinal plants. Chemical analysis yielded data on the content of reducing sugars (glucose and fructose) that dominate the honey matrix, and of the minor constituents of protein, phenols and flavonoids. Standard chemical assays were used to develop a database of water content, electrical conductivity, pH, ash content, visual appearance and colour intensity. Physicochemical characteristics were related to structural behaviour of the four honey types, as recorded by small-deformation dynamic oscillation in shear, micro- and modulated differential scanning calorimetry, wide angle X-ray diffraction and infrared spectroscopy...
February 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/28901255/health-benefits-of-manuka-honey-as-an-essential-constituent-for-tissue-regeneration
#8
Kamal Niaz, Faheem Maqbool, Haji Bahadar, Mohammad Abdollahi
Honey is known for its therapeutic properties from ancient civilizations but only since last few decades its mechanism has been studied on how it causes epithelial regeneration leading to wound and ulcer healing.. In the present review the health perspectives of honey, its chemical composition with special reference to flavonoids, polyphenol composition and other bioactive trace compounds used in tissue regeneration have been highlighted. Honey can inhibit carcinogenesis by moderating with molecular processes of initiation, advancement and progression stage of cancer cells, therefore it is considered a promising anti-cancer agent...
September 11, 2017: Current Drug Metabolism
https://www.readbyqxmd.com/read/28873061/comprehensive-in-situ-killing-of-six-common-wound-pathogens-with-manuka-honey-dressings-using-a-modified-aatcc-tm100
#9
Denis Watson, Stephen Bergquist, Julie Nicholson, David H Norrie
OBJECTIVE: While Manuka honey in vitro is strongly antimicrobial, there have been, to the best of the authors' knowledge, no studies showing that dressings impregnated with Manuka honey can kill organisms in the dressing itself. MATERIALS AND METHODS: The investigators used the American Association of Textile Chemists and Colorists' 100 test methodology to compare honey-impregnated dressings with control dressings (without honey) on the ability to kill common wound pathogens...
July 26, 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/28856117/the-il-6-stat3-signaling-pathway-is-an-early-target-of-manuka-honey-induced-suppression-of-human-breast-cancer-cells
#10
Priyanka Aryappalli, Sarah S Al-Qubaisi, Samir Attoub, Junu A George, Kholoud Arafat, Khalil B Ramadi, Yassir A Mohamed, Mezoon M Al-Dhaheri, Ashraf Al-Sbiei, Maria J Fernandez-Cabezudo, Basel K Al-Ramadi
There is renewed interest in the potential use of natural compounds in cancer therapy. Previously, we demonstrated the anti-tumor properties of manuka honey (MH) against several cancers. However, the underlying mechanism and molecular targets of this activity remain unknown. For this study, the early targets of MH and its modulatory effects on proliferation, invasiveness, and angiogenic potential were investigated using two human breast cancer cell lines, the triple-negative MDA-MB-231 cells and estrogen receptor-positive MCF-7 cells, and the non-neoplastic breast epithelial MCF-10A cell line...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28855819/antimicrobial-effect-of-different-types-of-honey-on-staphylococcus-aureus
#11
Saad B Almasaudi, Alaa A M Al-Nahari, El Sayed M Abd El-Ghany, Elie Barbour, Saad M Al Muhayawi, Soad Al-Jaouni, Esam Azhar, Mohamad Qari, Yousef A Qari, Steve Harakeh
Honey exhibits antimicrobial activities against a wide range of bacteria in different milieu. This study aims to compare the effects of five types of honey (both imported and local Saudi honey) against Staphylococcus aureus. The five types of honey (Manuka Honey UMF +20, Manuka Honey UMF +16, Active +10 Manuka Honey, Sidr honey and Nigella sativa honey) were evaluated for their bactericidal/bacteriostatic activities against both methicillin resistant and sensitive S. aureus. The inhibitory effect of honey on bacterial growth was evident at concentrations of 20% and 10% (v/v)...
September 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28830809/hydrogel-film-loaded-with-new-formula-from-manuka-honey-for-treatment-of-chronic-wound-infections
#12
Fady F Abd El-Malek, Amany S Yousef, Samy A El-Assar
OBJECTIVES: Chronic wound infections can be effectively treated using hydrogel loaded with an extract from manuka honey. METHODS: This study was performed on bacterial isolates from patients with infected wounds at Alexandria Main University Hospital (Alexandria, Egypt). Isolates were exposed to hydrogel sheets composed of chitosan and gelatin and loaded with a new formula from manuka honey. RESULTS: The results illustrate the antibacterial activity of the formula extracted from manuka honey against Staphylococcus aureus, Streptococcus pyogenes, Acinetobacter baumannii, Pseudomonas aeruginosa and Proteus mirabilis...
August 19, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28813014/antibacterial-properties-of-nonwoven-wound-dressings-coated-with-manuka-honey-or-methylglyoxal
#13
Sophie E L Bulman, Giuseppe Tronci, Parikshit Goswami, Chris Carr, Stephen J Russell
Manuka honey (MH) is used as an antibacterial agent in bioactive wound dressings via direct impregnation onto a suitable substrate. MH provides unique antibacterial activity when compared with conventional honeys, owing partly to one of its constituents, methylglyoxal (MGO). Aiming to investigate an antibiotic-free antimicrobial strategy, we studied the antibacterial activity of both MH and MGO (at equivalent MGO concentrations) when applied as a physical coating to a nonwoven fabric wound dressing. When physically coated on to a cellulosic hydroentangled nonwoven fabric, it was found that concentrations of 0...
August 16, 2017: Materials
https://www.readbyqxmd.com/read/28714567/comparison-of-the-effects-of-topical-application-of-umf20-and-umf5-manuka-honey-with-a-generic-multifloral-honey-on-wound-healing-variables-in-an-uncontaminated-surgical-equine-distal-limb-wound-model
#14
A S Tsang, A J Dart, A Sole-Guitart, C M Dart, N R Perkins, L B Jeffcott
OBJECTIVE: To compare the effect of application of manuka honey with unique manuka factor (UMF) 5 or 20 with a generic multifloral honey on equine wound healing variables. METHODS: Two full-thickness skin wounds (2.5 × 2.5 cm) were created on the metatarsus of both hindlimbs of eight Standardbred horses. The wounds on each horse were assigned to 1 of 4 treatments: UMF20 (UMF20) and UMF5 (UMF5) manuka honey; generic multifloral honey (GH); and a saline control...
July 17, 2017: Australian Veterinary Journal
https://www.readbyqxmd.com/read/28678730/comprehensive-in-situ-killing-of-six-common-wound-pathogens-with-manuka-honey-dressings-using-a-modified-aatcc-tm100
#15
Denis Watson, Stephen Bergquist, Julie Nicholson, David H Norrie
OBJECTIVE: While Manuka honey in vitro is strongly antimicrobial, there have been, to the best of the authors' knowledge, no studies showing that dressings impregnated with Manuka honey can kill organisms in the dressing itself. MATERIALS AND METHODS: The investigators used the American Association of Textile Chemists and Colorists' 100 test methodology to compare honey-impregnated dressings with control dressings (without honey) on the ability to kill common wound pathogens...
June 28, 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/28672824/myrtaceae-plant-essential-oils-and-their-%C3%AE-triketone-components-as-insecticides-against-drosophila-suzukii
#16
Chung Gyoo Park, Miyeon Jang, Eunsik Shin, Junheon Kim
Spotted wing drosophila (SWD, Drosophila suzukii (Matsumura), Diptera: Drosophilidae) is recognized as an economically important pest in North America and Europe as well as in Asia. Assessments were made for fumigant and contact toxicities of six Myrtaceae plant essential oils (EOs) and their components to find new alternative types of insecticides active against SWD. Among the EOs tested, Leptospermum citratum EO, consisting mainly of geranial and neral, exhibited effective fumigant activity. Median lethal dose (LD50; mg/L) values of L...
June 24, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28595460/sub-inhibitory-stress-with-essential-oil-affects-enterotoxins-production-and-essential-oil-susceptibility-in-staphylococcus-aureus
#17
Barbara Turchi, Simone Mancini, Luisa Pistelli, Basma Najar, Domenico Cerri, Filippo Fratini
Fourteen wild strains of Staphylococcus aureus positive for gene sea were tested for enterotoxins production and the minimum inhibitory concentration of Leptospermum scoparium, Origanum majorana, Origanum vulgare, Satureja montana and Thymus vulgaris essential oils (EOs) were determined. After this trial, bacteria stressed with sub-inhibitory concentration of each EO were tested for enterotoxins production by an immunoenzymatic assay and resistance to the same EO. Oregano oil exhibited the highest antibacterial activity followed by manuka and thyme oils...
June 8, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28585260/randomised-controlled-trial-of-topical-antibacterial-manuka-leptospermum-species-honey-for-evaporative-dry-eye-due-to-meibomian-gland-dysfunction
#18
Julie M Albietz, Katrina L Schmid
BACKGROUND: The aim was to evaluate the efficacy of standardised Manuka (Leptospermum species) antibacterial honey as adjunctive twice daily treatment to conventional therapy (warm compresses, lid massage and preservative-free lubricant), in participants with evaporative dry eye due to moderate to advanced meibomian gland dysfunction. METHODS: This prospective, open-label study involved 114 participants. After two weeks of conventional therapy participants were randomised to one of three treatment groups: Optimel Antibacterial Manuka Eye Gel (98 per cent Leptospermum species honey) plus conventional therapy (n = 37), Optimel Manuka plus Lubricant Eye Drops (16 per cent Leptospermum species honey) plus conventional therapy (n = 37) and a control (conventional therapy) (n = 40)...
June 6, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28511700/a-new-easy-to-make-pectin-honey-hydrogel-enhances-wound-healing-in-rats
#19
Gessica Giusto, Cristina Vercelli, Francesco Comino, Vittorio Caramello, Massimiliano Tursi, Marco Gandini
BACKGROUND: Honey, alone or in combination, has been used for wound healing since ancient times and has reemerged as a topic of interest in the last decade. Pectin has recently been investigated for its use in various biomedical applications such as drug delivery, skin protection, and scaffolding for cells. The aim of the present study was to develop and evaluate a pectin-honey hydrogel (PHH) as a wound healing membrane and to compare this dressing to liquid honey. METHODS: Thirty-six adult male Sprague-Dawley rats were anesthetized and a 2 × 2 cm excisional wound was created on the dorsum...
May 16, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28490123/kinetics-of-conversion-of-dihydroxyacetone-to-methylglyoxal-in-new-zealand-m%C3%A4-nuka-honey-part-iv-formation-of-hmf
#20
Megan N C Grainger, Adrian Owens, Merilyn Manley-Harris, Joseph R Lane, Richard J Field
During a study of the conversion of dihydroxyacetone (DHA) to methylglyoxal (MGO) in maturing New Zealand mānuka honey, the kinetics of formation of 5-(hydroxymethyl)furfural (HMF) was studied at temperatures from 4 to 37°C. Formation of HMF was first-order during an induction period and zero-order thereafter indicating that the mechanism includes the formation of certain critical intermediates and that these require time to build up; the duration of the induction period depended primarily upon temperature...
October 1, 2017: Food Chemistry
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